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Conserved domains on  [gi|1921167327|gb|QOU09548|]
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replication protein [Duck circovirus]

Protein Classification

replication-associated family protein( domain architecture ID 10261052)

replication-associated family protein similar to replication-associated protein and Para-Rep C1/7/9, both of which are ATP-dependent helicases

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 163-247 4.15e-19

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 80.34  E-value: 4.15e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327 163 IVLIGPPGTGKSRYA----------FEFPAENKYYK-PRGKWWDGYSGNDVVVMDDFYGW---LPYDDLLRITDRYPLRV 228
Cdd:pfam00910   1 IWLYGPPGCGKSTLAkylarallkkLGLPKDSVYSRnPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPP 80

                          90       100
                  ....*....|....*....|..
gi 1921167327 229 EFKGGM---TQFVAKTLIITSN 247
Cdd:pfam00910  81 PMAALEekgTPFTSKFVIVTSN 102
Viral_Rep super family cl03577
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 11-95 9.72e-17

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


The actual alignment was detected with superfamily member pfam02407:

Pssm-ID: 280553  Cd Length: 82  Bit Score: 73.37  E-value: 9.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327  11 RWVFTINNPTfedyvhvlEFCTL---DNCKFAIVGEEKGANGTPHLQGFLNLRSNARAAALEESLGGRAWLSRARGSDED 87
Cdd:pfam02407   3 CWCFTLNNPT--------EFLSLfsqDELKYFVYQDERGTTGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEE 74


                  ....*...
gi 1921167327  88 NEEYCSKE 95
Cdd:pfam02407  75 ARDYCMKE 82
CDC6 super family cl34277
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
139-179 9.23e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


The actual alignment was detected with superfamily member COG1474:

Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 37.13  E-value: 9.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1921167327 139 IFGRD--LERLRHLIVDTQRDWKTEVIVLIGPPGTGKS---RYAFE 179
Cdd:COG1474    28 LPHREeeIEELASALRPALRGERPSNVLIYGPTGTGKTavaKYVLE 73
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 163-247 4.15e-19

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 80.34  E-value: 4.15e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327 163 IVLIGPPGTGKSRYA----------FEFPAENKYYK-PRGKWWDGYSGNDVVVMDDFYGW---LPYDDLLRITDRYPLRV 228
Cdd:pfam00910   1 IWLYGPPGCGKSTLAkylarallkkLGLPKDSVYSRnPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPP 80

                          90       100
                  ....*....|....*....|..
gi 1921167327 229 EFKGGM---TQFVAKTLIITSN 247
Cdd:pfam00910  81 PMAALEekgTPFTSKFVIVTSN 102
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 11-95 9.72e-17

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 73.37  E-value: 9.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327  11 RWVFTINNPTfedyvhvlEFCTL---DNCKFAIVGEEKGANGTPHLQGFLNLRSNARAAALEESLGGRAWLSRARGSDED 87
Cdd:pfam02407   3 CWCFTLNNPT--------EFLSLfsqDELKYFVYQDERGTTGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEE 74


                  ....*...
gi 1921167327  88 NEEYCSKE 95
Cdd:pfam02407  75 ARDYCMKE 82
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
139-179 9.23e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 37.13  E-value: 9.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1921167327 139 IFGRD--LERLRHLIVDTQRDWKTEVIVLIGPPGTGKS---RYAFE 179
Cdd:COG1474    28 LPHREeeIEELASALRPALRGERPSNVLIYGPTGTGKTavaKYVLE 73
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 163-247 4.15e-19

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 80.34  E-value: 4.15e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327 163 IVLIGPPGTGKSRYA----------FEFPAENKYYK-PRGKWWDGYSGNDVVVMDDFYGW---LPYDDLLRITDRYPLRV 228
Cdd:pfam00910   1 IWLYGPPGCGKSTLAkylarallkkLGLPKDSVYSRnPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPP 80

                          90       100
                  ....*....|....*....|..
gi 1921167327 229 EFKGGM---TQFVAKTLIITSN 247
Cdd:pfam00910  81 PMAALEekgTPFTSKFVIVTSN 102
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 11-95 9.72e-17

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 73.37  E-value: 9.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327  11 RWVFTINNPTfedyvhvlEFCTL---DNCKFAIVGEEKGANGTPHLQGFLNLRSNARAAALEESLGGRAWLSRARGSDED 87
Cdd:pfam02407   3 CWCFTLNNPT--------EFLSLfsqDELKYFVYQDERGTTGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEE 74


                  ....*...
gi 1921167327  88 NEEYCSKE 95
Cdd:pfam02407  75 ARDYCMKE 82
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 140-226 2.25e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 37.87  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1921167327 140 FGRD--LERLRHLIvDTQRDWKTEVIVLIGPPGTGKS---RYAFEFPAENKYYKPRGKWwdgysgndvvvmDDFygwLPY 214
Cdd:pfam13191   3 VGREeeLEQLLDAL-DRVRSGRPPSVLLTGEAGTGKTtllRELLRALERDGGYFLRGKC------------DEN---LPY 66

                          90
                  ....*....|..
gi 1921167327 215 DDLLRITDRYPL 226
Cdd:pfam13191  67 SPLLEALTREGL 78
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
139-179 9.23e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 37.13  E-value: 9.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1921167327 139 IFGRD--LERLRHLIVDTQRDWKTEVIVLIGPPGTGKS---RYAFE 179
Cdd:COG1474    28 LPHREeeIEELASALRPALRGERPSNVLIYGPTGTGKTavaKYVLE 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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