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Conserved domains on  [gi|1654797638|gb|TLD30795|]
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hypothetical protein PspLS_03052 [Pyricularia sp. CBS 133598]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AVR-Pik_HID cd23000
HMA interaction domain found in Pyricularia oryzae AVR-Pik and similar proteins; Microbial ...
 145-242 1.65e-32

HMA interaction domain found in Pyricularia oryzae AVR-Pik and similar proteins; Microbial plant pathogens secrete effector proteins that can be recognized by plant intracellular nucleotide-binding leucine-rich repeat (NLR) receptors, initiating an immune response. AVR-Pik protein is an effector from the rice blast fungus Pyricularia oryzae (also known as Magnaporthe oryzae). It binds and stabilizes rice heavy metal-associated (HMA)-domain containing NLR proteins to co-opt their function to suppress immunity. AVR-Pik adopts a six-stranded beta-sandwich structure. There are four AVR-Pik alleles, AVR-PikA, AVR-PikC, AVR-PikD, AVR-PikE.


:

Pssm-ID: 439386  Cd Length: 74  Bit Score: 113.30  E-value: 1.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1654797638 145 HYDDPDVIDHAGQAPSDCFYFLFEYAhptrtvkggwfkkdtkepmgpkkwILRDRGSQQSGNSLSYQLFPLDAIFKTDDD 224
Cdd:cd23000     1 RERDPNFIDHPGIPPPDCFWFMFKNA------------------------VRQDAGTCYSDWSFDMKVGPNWVIIKSDEN 56

                          90
                  ....*....|....*...
gi 1654797638 225 CNVKANLPSNWWVVGRKR 242
Cdd:cd23000    57 CNLSGDFPPGWIVLGKKR 74
 
Name Accession Description Interval E-value
AVR-Pik_HID cd23000
HMA interaction domain found in Pyricularia oryzae AVR-Pik and similar proteins; Microbial ...
 145-242 1.65e-32

HMA interaction domain found in Pyricularia oryzae AVR-Pik and similar proteins; Microbial plant pathogens secrete effector proteins that can be recognized by plant intracellular nucleotide-binding leucine-rich repeat (NLR) receptors, initiating an immune response. AVR-Pik protein is an effector from the rice blast fungus Pyricularia oryzae (also known as Magnaporthe oryzae). It binds and stabilizes rice heavy metal-associated (HMA)-domain containing NLR proteins to co-opt their function to suppress immunity. AVR-Pik adopts a six-stranded beta-sandwich structure. There are four AVR-Pik alleles, AVR-PikA, AVR-PikC, AVR-PikD, AVR-PikE.


Pssm-ID: 439386  Cd Length: 74  Bit Score: 113.30  E-value: 1.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1654797638 145 HYDDPDVIDHAGQAPSDCFYFLFEYAhptrtvkggwfkkdtkepmgpkkwILRDRGSQQSGNSLSYQLFPLDAIFKTDDD 224
Cdd:cd23000     1 RERDPNFIDHPGIPPPDCFWFMFKNA------------------------VRQDAGTCYSDWSFDMKVGPNWVIIKSDEN 56

                          90
                  ....*....|....*...
gi 1654797638 225 CNVKANLPSNWWVVGRKR 242
Cdd:cd23000    57 CNLSGDFPPGWIVLGKKR 74
 
Name Accession Description Interval E-value
AVR-Pik_HID cd23000
HMA interaction domain found in Pyricularia oryzae AVR-Pik and similar proteins; Microbial ...
 145-242 1.65e-32

HMA interaction domain found in Pyricularia oryzae AVR-Pik and similar proteins; Microbial plant pathogens secrete effector proteins that can be recognized by plant intracellular nucleotide-binding leucine-rich repeat (NLR) receptors, initiating an immune response. AVR-Pik protein is an effector from the rice blast fungus Pyricularia oryzae (also known as Magnaporthe oryzae). It binds and stabilizes rice heavy metal-associated (HMA)-domain containing NLR proteins to co-opt their function to suppress immunity. AVR-Pik adopts a six-stranded beta-sandwich structure. There are four AVR-Pik alleles, AVR-PikA, AVR-PikC, AVR-PikD, AVR-PikE.


Pssm-ID: 439386  Cd Length: 74  Bit Score: 113.30  E-value: 1.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1654797638 145 HYDDPDVIDHAGQAPSDCFYFLFEYAhptrtvkggwfkkdtkepmgpkkwILRDRGSQQSGNSLSYQLFPLDAIFKTDDD 224
Cdd:cd23000     1 RERDPNFIDHPGIPPPDCFWFMFKNA------------------------VRQDAGTCYSDWSFDMKVGPNWVIIKSDEN 56

                          90
                  ....*....|....*...
gi 1654797638 225 CNVKANLPSNWWVVGRKR 242
Cdd:cd23000    57 CNLSGDFPPGWIVLGKKR 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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