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Conserved domains on  [gi|1722905968|gb|TXD32272|]
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efflux RND transporter permease subunit, partial [Lujinxingia vulgaris]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AcrB super family cl34050
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-174 4.30e-45

Multidrug efflux pump subunit AcrB [Defense mechanisms];


The actual alignment was detected with superfamily member COG0841:

Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 158.34  E-value: 4.30e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:COG0841    435 IASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRG 514

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:COG0841    515 YGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVES 594

                          170
                   ....*....|....
gi 1722905968  161 YTTLAGYDIIASSQ 174
Cdd:COG0841    595 VFSVVGFSGGGSGS 608
 
Name Accession Description Interval E-value
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-174 4.30e-45

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 158.34  E-value: 4.30e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:COG0841    435 IASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRG 514

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:COG0841    515 YGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVES 594

                          170
                   ....*....|....
gi 1722905968  161 YTTLAGYDIIASSQ 174
Cdd:COG0841    595 VFSVVGFSGGGSGS 608
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 1-179 3.91e-34

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 127.03  E-value: 3.91e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:pfam00873  436 VAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRG 515

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:pfam00873  516 YAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVES 595

                          170
                   ....*....|....*....
gi 1722905968  161 YTTLAGYDIIASSQRTSAG 179
Cdd:pfam00873  596 VFAVTGFAFSGDNNGPNSG 614
2A0602 TIGR00915
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ...
 1-174 2.31e-32

The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 273335 [Multi-domain]  Cd Length: 1044  Bit Score: 121.76  E-value: 2.31e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLA----PALSALLLGKEDSGKESWFFRYFNSGFQK 76
Cdd:TIGR00915  443 VGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTpalcATMLKPIEKGEHHEKKGGFFGWFNRMFDS 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   77 ISNGYANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSME 156
Cdd:TIGR00915  523 STHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKE 602

                          170       180
                   ....*....|....*....|
gi 1722905968  157 --EIEDYTTLAGYDIIASSQ 174
Cdd:TIGR00915  603 kaNVESVFTVNGFSFAGRGQ 622
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
1-174 4.57e-28

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 109.72  E-value: 4.57e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDsgKESWFFRYFNSGFQKISNG 80
Cdd:NF033617   434 IAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLKANE--KPGRFARAVDRFFDGLTAR 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:NF033617   512 YGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQS 591

                          170
                   ....*....|....
gi 1722905968  161 YTTLAGYDIIASSQ 174
Cdd:NF033617   592 LTSFNGVGGNPGDN 605
PRK15127 PRK15127
multidrug efflux RND transporter permease subunit AcrB;
1-176 4.80e-25

multidrug efflux RND transporter permease subunit AcrB;


Pssm-ID: 185081 [Multi-domain]  Cd Length: 1049  Bit Score: 100.75  E-value: 4.80e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALL---LGKEDSGK-ESWFFRYFNSGFQK 76
Cdd:PRK15127   443 VGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMlkpIAKGDHGEgKKGFFGWFNRMFEK 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   77 ISNGYANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSME 156
Cdd:PRK15127   523 STHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKE 602

                          170       180
                   ....*....|....*....|..
gi 1722905968  157 E--IEDYTTLAGYDIIASSQRT 176
Cdd:PRK15127   603 KnnVESVFAVNGFGFAGRGQNT 624
 
Name Accession Description Interval E-value
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-174 4.30e-45

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 158.34  E-value: 4.30e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:COG0841    435 IASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRG 514

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:COG0841    515 YGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVES 594

                          170
                   ....*....|....
gi 1722905968  161 YTTLAGYDIIASSQ 174
Cdd:COG0841    595 VFSVVGFSGGGSGS 608
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 1-179 3.91e-34

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 127.03  E-value: 3.91e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:pfam00873  436 VAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRG 515

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:pfam00873  516 YAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVES 595

                          170
                   ....*....|....*....
gi 1722905968  161 YTTLAGYDIIASSQRTSAG 179
Cdd:pfam00873  596 VFAVTGFAFSGDNNGPNSG 614
2A0602 TIGR00915
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ...
 1-174 2.31e-32

The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 273335 [Multi-domain]  Cd Length: 1044  Bit Score: 121.76  E-value: 2.31e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLA----PALSALLLGKEDSGKESWFFRYFNSGFQK 76
Cdd:TIGR00915  443 VGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTpalcATMLKPIEKGEHHEKKGGFFGWFNRMFDS 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   77 ISNGYANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSME 156
Cdd:TIGR00915  523 STHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKE 602

                          170       180
                   ....*....|....*....|
gi 1722905968  157 --EIEDYTTLAGYDIIASSQ 174
Cdd:TIGR00915  603 kaNVESVFTVNGFSFAGRGQ 622
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
1-174 4.57e-28

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 109.72  E-value: 4.57e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDsgKESWFFRYFNSGFQKISNG 80
Cdd:NF033617   434 IAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLKANE--KPGRFARAVDRFFDGLTAR 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIED 160
Cdd:NF033617   512 YGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQS 591

                          170
                   ....*....|....
gi 1722905968  161 YTTLAGYDIIASSQ 174
Cdd:NF033617   592 LTSFNGVGGNPGDN 605
PRK15127 PRK15127
multidrug efflux RND transporter permease subunit AcrB;
1-176 4.80e-25

multidrug efflux RND transporter permease subunit AcrB;


Pssm-ID: 185081 [Multi-domain]  Cd Length: 1049  Bit Score: 100.75  E-value: 4.80e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALL---LGKEDSGK-ESWFFRYFNSGFQK 76
Cdd:PRK15127   443 VGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMlkpIAKGDHGEgKKGFFGWFNRMFEK 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   77 ISNGYANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSME 156
Cdd:PRK15127   523 STHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKE 602

                          170       180
                   ....*....|....*....|..
gi 1722905968  157 E--IEDYTTLAGYDIIASSQRT 176
Cdd:PRK15127   603 KnnVESVFAVNGFGFAGRGQNT 624
PRK10555 PRK10555
multidrug efflux RND transporter permease AcrD;
1-157 6.80e-25

multidrug efflux RND transporter permease AcrD;


Pssm-ID: 182544 [Multi-domain]  Cd Length: 1037  Bit Score: 100.29  E-value: 6.80e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALL---LGKEDSGKESWFFRYFNSGFQKI 77
Cdd:PRK10555   443 VGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAMILTPALCATLlkpLKKGEHHGQKGFFGWFNRMFNRN 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   78 SNGYANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEE 157
Cdd:PRK10555   523 AERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEK 602
PRK09577 PRK09577
multidrug efflux RND transporter permease subunit;
1-169 3.04e-22

multidrug efflux RND transporter permease subunit;


Pssm-ID: 169981 [Multi-domain]  Cd Length: 1032  Bit Score: 92.99  E-value: 3.04e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKES--WFFRYFNSGFQKIS 78
Cdd:PRK09577   442 VGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAFLALSLTPALCATLLKPVDGDHHEkrGFFGWFNRFVARST 521

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   79 NGYANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEI 158
Cdd:PRK09577   522 QRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPV 601

                          170
                   ....*....|.
gi 1722905968  159 EDYTTLAGYDI 169
Cdd:PRK09577   602 AYTFALGGFNL 612
PRK10614 PRK10614
multidrug efflux system subunit MdtC; Provisional
 1-127 9.85e-13

multidrug efflux system subunit MdtC; Provisional


Pssm-ID: 182589 [Multi-domain]  Cd Length: 1025  Bit Score: 65.52  E-value: 9.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLgKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:PRK10614   436 LSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMCAWLL-KSSKPREQKRLRGFGRMLVALQQG 514

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVAL 127
Cdd:PRK10614   515 YGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLM 561
PRK09579 PRK09579
multidrug efflux RND transporter permease subunit;
1-172 4.08e-11

multidrug efflux RND transporter permease subunit;


Pssm-ID: 169983 [Multi-domain]  Cd Length: 1017  Bit Score: 60.62  E-value: 4.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKED--SGKESWFFRYFNS---GFQ 75
Cdd:PRK09579   435 VSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLLRHEEnpSGLAHRLDRLFERlkqRYQ 514

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   76 KISNGYANTvqwflRHAVlgiLVF-VVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLS 154
Cdd:PRK09579   515 RALHGTLNT-----RPVV---LVFaVIVLALIPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKS 586

                          170
                   ....*....|....*...
gi 1722905968  155 MEEIEDYTTLAGYDIIAS 172
Cdd:PRK09579   587 FPEYYSSFQINGFNGVQS 604
PRK10503 PRK10503
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
1-168 9.52e-11

MdtB/MuxB family multidrug efflux RND transporter permease subunit;


Pssm-ID: 182501 [Multi-domain]  Cd Length: 1040  Bit Score: 59.74  E-value: 9.52e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYFNSGFQKISNG 80
Cdd:PRK10503   445 ISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASERMFDRVIAA 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   81 YANTVQWFLRH--AVLGILVFVVVIGSVAFLInrLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEI 158
Cdd:PRK10503   525 YGRGLAKVLNHpwLTLSVALSTLLLTVLLWIF--IPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAV 602

                          170
                   ....*....|
gi 1722905968  159 EDYTTLAGYD 168
Cdd:PRK10503   603 QSLTSFVGVD 612
CusA COG3696
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
1-159 2.93e-07

Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];


Pssm-ID: 442911 [Multi-domain]  Cd Length: 1031  Bit Score: 49.26  E-value: 2.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    1 VAATLTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRyfnsgfqKISNG 80
Cdd:COG3696    445 FFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVR-------WLKRL 517

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1722905968   81 YANTVQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQGVALVAYQLPPVSALGRTEAVRDKVSKMLLSMEEIE 159
Cdd:COG3696    518 YRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVE 596
2A0601 TIGR00914
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ...
 5-172 4.82e-03

heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 129992 [Multi-domain]  Cd Length: 1051  Bit Score: 37.05  E-value: 4.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968    5 LTLISVFAPVAFLGGMTGELYRQFAVTIAVSVMFSGIVALTLAPALSALLLGKEDSGKESWFFRYfnsgfqkISNGYANT 84
Cdd:TIGR00914  457 LIITLVFLPIFTLTGVEGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRV-------LKRRYEPL 529

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1722905968   85 VQWFLRHAVLGILVFVVVIGSVAFLINRLPPGLVPQEDQG-VALVAYQLPPVSaLGRTEAVRDKVSKMLLSMEEIEDYTT 163
Cdd:TIGR00914  530 LERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGdLAYQALRIPGTS-LAQSVAMQQTLEKLIKSFPEVARVFA 608


                   ....*....
gi 1722905968  164 LAGYDIIAS 172
Cdd:TIGR00914  609 KTGTAEIAT 617
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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