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Conserved domains on  [gi|2161959099|gb|UGC41818|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Heleioporus psammophilus]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-232 4.45e-106

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00068:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 458  Bit Score: 313.39  E-value: 4.45e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00068  224 PIAGSMILAAVLLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALI 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00068  304 QTPWSFSGAIILMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMV 383

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00068  384 SLFNWSNWTILITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELIS 455
 
Name Accession Description Interval E-value
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-232 4.45e-106

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 313.39  E-value: 4.45e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00068  224 PIAGSMILAAVLLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALI 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00068  304 QTPWSFSGAIILMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMV 383

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00068  384 SLFNWSNWTILITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELIS 455
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 29-232 5.85e-40

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 142.91  E-value: 5.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  29 ESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLAN 108
Cdd:COG1008   269 EASAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVSHGLITAALFLLVG 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 109 TAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILLAGLSIMFATSYSLYLF 188
Cdd:COG1008   349 VLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAALGLILTAAYLLWMY 428

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2161959099 189 wssQREY---LPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:COG1008   429 ---QRVFfgpLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLL 472
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-232 1.11e-33

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 125.82  E-value: 1.11e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTS-SMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:TIGR01972 234 PTAGSVILAGVLLKMGTYGFLRFNlPLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIF 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:TIGR01972 314 SFNELGISGAVFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLIL 393

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFAtsySLYLFWSSQREYL----PSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:TIGR01972 394 LGSFKVNPVVAFLAALGIVLA---AAYMLTLYKRVFFgelsNPEVAEFPDLNGREIAVLAPLVVLILFLGLYPNPLL 467
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-175 9.89e-28

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 106.63  E-value: 9.89e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:pfam00361 113 PTPVSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGA 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLA-NTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:pfam00361 193 GTIYGIQAAIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLIL 272

                         170
                  ....*....|....*.
gi 2161959099 160 LSVFKWAPYSILLAGL 175
Cdd:pfam00361 273 AAAVAASWIFLVLAGV 288
 
Name Accession Description Interval E-value
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-232 4.45e-106

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 313.39  E-value: 4.45e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00068  224 PIAGSMILAAVLLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALI 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00068  304 QTPWSFSGAIILMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMV 383

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00068  384 SLFNWSNWTILITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELIS 455
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-231 3.38e-91

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 275.54  E-value: 3.38e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00124  224 PIAGSMVLAAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMI 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00124  304 QTPWSLSGAMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMT 383

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELI 231
Cdd:MTH00124  384 SLFNWSPTTIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELI 454
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-231 1.55e-79

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 245.57  E-value: 1.55e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00110  224 PIAGSMVLAAILLKLGGYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILI 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00110  304 QTPWSFMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIM 383

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELI 231
Cdd:MTH00110  384 SSFSWSNITIILMGLNMLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKII 454
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-231 5.27e-73

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 229.07  E-value: 5.27e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00127  225 PIAGSMVLAAVLLKLGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILI 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00127  305 QTPWGFTGALILMIAHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIIT 384

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELI 231
Cdd:MTH00127  385 SLFNWSPWTLALTGLGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELI 455
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-231 8.63e-69

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 217.88  E-value: 8.63e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00206  220 PVAGSMVLAGVLLKLGGYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILS 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00206  300 GSPWGFKGALLLMIAHGLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIIT 379

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELI 231
Cdd:MTH00206  380 SLFSWSNFTLPLLGLGFLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-232 2.51e-61

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 198.66  E-value: 2.51e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHE-SFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:MTH00044  225 PVAGSMILAAILLKLGGYGLIRLINLFSLpSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIF 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:MTH00044  305 SGTNWGINGALILMIAHGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLII 384

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00044  385 SSIISWSILSFPIIGLATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNIIL 457
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-232 6.40e-52

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 173.80  E-value: 6.40e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00163  212 PVSGSMILAGVLLKLGGYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMT 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00163  292 FSYWGLMGSLLMMIGHGLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLIN 371

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00163  372 SLISWSKLSMIFLMLLSFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLFM 443
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-232 6.28e-50

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 168.09  E-value: 6.28e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLR---TSSMIHESFHPLappLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAA 77
Cdd:MTH00150  183 PVAGSMILAGILLKLGGYGILRmmmVFSLSSSSFSIF---LISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAG 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  78 TMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELL 157
Cdd:MTH00150  260 VLSNTSWGWVGALIMMVSHGFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIM 339

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2161959099 158 ILLSVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00150  340 IFPSLISYSPWFFVPLGLMVFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLLF 414
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-232 3.86e-47

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 161.45  E-value: 3.86e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00014  218 PVAGSMILAGILLKLGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMS 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00014  298 NTSWGWQGALAMMIAHGLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLT 377

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00014  378 SILSSSLSTAILLAITSFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLIT 449
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-232 4.69e-44

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 153.21  E-value: 4.69e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:MTH00205  216 PVSGSMILAGVLLKLGGYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFS 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILL 160
Cdd:MTH00205  296 NTSWGMNGAIIMMVAHGLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIM 375

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 161 SVFKWAPYSILLAGLSIMFATSYSLYLFWSSQREYLPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:MTH00205  376 SLLSSSKISGIPLSLISFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIFI 447
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 29-232 5.85e-40

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 142.91  E-value: 5.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  29 ESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLAN 108
Cdd:COG1008   269 EASAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVSHGLITAALFLLVG 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 109 TAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILLAGLSIMFATSYSLYLF 188
Cdd:COG1008   349 VLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAALGLILTAAYLLWMY 428

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2161959099 189 wssQREY---LPSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:COG1008   429 ---QRVFfgpLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLL 472
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-232 8.77e-35

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 129.17  E-value: 8.77e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTS-SMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:PRK05846  242 PTAGSVLLAGILLKMGAYGLLRFSlPLFPDASHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIF 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:PRK05846  322 AGNQLGIQGAIFQMISHGLSSAALFLLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLIL 401

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFATSYSLYLFwssQREYL------PSHMKSLSPtmtREHILLALHITPIIMLTLKPELIF 232
Cdd:PRK05846  402 LGSFQVNPVIAFIATTGLILAAVYSLWLY---QRVMFgpvkneVAKLKDLNG---RELLILLPLVALLLLLGVYPKPLL 474
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-232 1.11e-33

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 125.82  E-value: 1.11e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTS-SMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:TIGR01972 234 PTAGSVILAGVLLKMGTYGFLRFNlPLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIF 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:TIGR01972 314 SFNELGISGAVFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLIL 393

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFAtsySLYLFWSSQREYL----PSHMKSLSPTMTREHILLALHITPIIMLTLKPELIF 232
Cdd:TIGR01972 394 LGSFKVNPVVAFLAALGIVLA---AAYMLTLYKRVFFgelsNPEVAEFPDLNGREIAVLAPLVVLILFLGLYPNPLL 467
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-188 1.97e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 114.38  E-value: 1.97e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTS-SMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:MTH00217  237 PVAGSVILAGVLLKLGGYGFIRFSwPLLPEASEYFSPLIQTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIF 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:MTH00217  317 SHTIQGLVAAIFLMLAHGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSL 396

                         170       180
                  ....*....|....*....|....*....
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFATSYSLYLF 188
Cdd:MTH00217  397 LAAFEYSYIVGVLASLGMVLSAGYSIYLY 425
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-188 6.27e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 112.85  E-value: 6.27e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTS-SMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:MTH00204  240 PVAGSVILAGILLKLGGYGFLRFSwPLFPAASEYFAPLIVMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLF 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:MTH00204  320 THTIEGLVAAVFLMLAHGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSL 399

                         170       180
                  ....*....|....*....|....*....
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFATSYSLYLF 188
Cdd:MTH00204  400 LAAFEYSLGLGVLVTSGMVWSAAYSLYLY 428
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-175 9.89e-28

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 106.63  E-value: 9.89e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMI 80
Cdd:pfam00361 113 PTPVSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGA 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  81 KSPWSVSGAMLLMISHGLVSSALFCLA-NTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:pfam00361 193 GTIYGIQAAIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLIL 272

                         170
                  ....*....|....*.
gi 2161959099 160 LSVFKWAPYSILLAGL 175
Cdd:pfam00361 273 AAAVAASWIFLVLAGV 288
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-187 1.22e-24

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 101.15  E-value: 1.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTS-SMIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATM 79
Cdd:MTH00226  261 PVAGSVLLAGILLKLGGYGLVRLSwPILPLGAQNLAPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLV 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  80 IKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLIL 159
Cdd:MTH00226  341 THDIIGLTGSIFIMLAHGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSI 420

                         170       180
                  ....*....|....*....|....*...
gi 2161959099 160 LSVFKWAPYSILLAGLSIMFATSYSLYL 187
Cdd:MTH00226  421 LSSFNWNPIIGVFVCSGVILSAVYSFYF 448
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 34-230 1.04e-22

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 95.48  E-value: 1.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  34 LAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYER 113
Cdd:PRK12561  250 FAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISGAMLQMISHGLIAAALFFLTGVTYER 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 114 TNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYS-------ILLAGLSIMFATSYSL- 185
Cdd:PRK12561  330 THTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVFLGITSSDVYSstfrtitILLAAVGLILTPIYLLs 409

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2161959099 186 ---YLFWSSQREYLPSHmKSLSPTMTREHILLALHITPIIMLTLKPEL 230
Cdd:PRK12561  410 mlrRVFYGPRSELLPAL-AVVEDAKPRELFIALSLLVPIIGIGFYPKL 456
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 28-190 3.95e-20

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 87.90  E-value: 3.95e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  28 HESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLA 107
Cdd:COG0651   265 ADPALFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKALLFLAA 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 108 NTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILLAGLSIMFATSYSLYL 187
Cdd:COG0651   345 GAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVR 424


                  ...
gi 2161959099 188 FWS 190
Cdd:COG0651   425 IFG 427
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 32-180 1.11e-18

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 84.21  E-value: 1.11e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  32 HPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAY 111
Cdd:PRK06458  278 DFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASGNVL 357

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 112 ERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFK---WAPYSILLAGLSIMFA 180
Cdd:PRK06458  358 QKYGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLArgpLLIAILLLLLLTLAFA 429
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 35-231 1.70e-17

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 80.52  E-value: 1.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  35 APPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERT 114
Cdd:PRK02546  279 APLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGAMLQMISHGLIGASLFFLVGATYDRT 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 115 NSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYS-------ILLAGLSIMFATSYSLYL 187
Cdd:PRK02546  359 HTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMSGFVAELMVFVGFATSDAYTlpfrvvvVFLAAVGVILTPIYLLSM 438

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2161959099 188 ----FWSSQREYLPSHMKsLSPTMTREHILLALHITPIIMLTLKPELI 231
Cdd:PRK02546  439 lreiFFGPENKELVSHEK-LVDAEPREVFIIACLLVPIIGIGLYPKLV 485
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
34-172 4.96e-17

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 79.36  E-value: 4.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  34 LAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYER 113
Cdd:PRK06473  270 LAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAAVFQMISHGLISALLFLLVGVVYKK 349

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 114 TNSRTMIVLQG---SQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILL 172
Cdd:PRK06473  350 TGSRDVDVLRGllnPERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPIFPVQTLL 411
ndhD CHL00011
NADH dehydrogenase subunit 4
 35-171 1.31e-15

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 74.98  E-value: 1.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  35 APPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERT 114
Cdd:CHL00011  277 SPWLVIVGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQIISHGFIGAALFFLAGTSYDRI 356

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2161959099 115 NSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSIL 171
Cdd:CHL00011  357 RLVYLDEMGGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIVFFGIITSQKYLLM 413
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 39-191 1.78e-14

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 71.48  E-value: 1.78e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  39 IIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRT 118
Cdd:MTH00094  217 IIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLMMMLAHGYTSTLMFYLIGEFYHISKSRL 296

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2161959099 119 MIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILLAGLSIMFATSYSLYLFWSS 191
Cdd:MTH00094  297 IYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFFFIFFYFLVSFYYSLFLIVSS 369
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
26-172 5.43e-14

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 70.51  E-value: 5.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  26 MIHESFHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFC 105
Cdd:PRK07363  262 LFPQTWSLVAPGLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLGAVAQMISHGLILALLFH 341

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 106 LANTAYERTNSRTMIVLQG--SQII-LPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILL 172
Cdd:PRK07363  342 LVGIVERKVGTRDLDVLNGlmNPIRgLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFSTFPIPTLL 411
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-216 2.75e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 68.46  E-value: 2.75e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  34 LAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYER 113
Cdd:PRK12667  294 LSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASGVFIHA 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 114 TNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYS----ILLAGLSIMFATSYSLYLFW 189
Cdd:PRK12667  374 AGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLpalvLLIASAISLVGYFRAWYSLF 453

                         170       180
                  ....*....|....*....|....*..
gi 2161959099 190 SSQREYLPSHMKSLSPTMTREHILLAL 216
Cdd:PRK12667  454 FGKPKSGEEVEHKESPSMSVVILVLAL 480
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 38-177 2.16e-12

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 65.71  E-value: 2.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSR 117
Cdd:PRK12647  262 LPLFGGLTMLTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHETGTR 341

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 118 TMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILLAGLSI 177
Cdd:PRK12647  342 DITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELIYEALLEAPLWSLILTVAAV 401
PRK12650 PRK12650
DUF4040 family protein;
38-185 2.80e-10

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 59.67  E-value: 2.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSR 117
Cdd:PRK12650  275 LIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTR 354

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2161959099 118 TMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFI---GELLILLSVFKWAPYSILL---AGLSIMFATSYSL 185
Cdd:PRK12650  355 DIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGFVskeGMLTAFLEAPGGNAGVVLLlvgAALGAVFTFAYSA 428
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 38-226 6.14e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 58.29  E-value: 6.14e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSR 117
Cdd:PRK06589  283 LIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKED 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 118 TMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVF--KWAPYSILLAGLSIMFATSYSLYLFWSSQREY 195
Cdd:PRK06589  363 QVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASeqNQPWLSIIVMLVVIASSILSALYLLKILSSIY 442

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2161959099 196 LPSHMKSLSPTMTREHILLALHITPIIMLTL 226
Cdd:PRK06589  443 KPSLSENSFITKSLPYLMQISVITCCCALTL 473
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-216 1.17e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 57.58  E-value: 1.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  33 PLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYE 112
Cdd:PRK08375  269 GLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMKGALFLAAGAIEV 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 113 RTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVF---KWAPYSILLAG--LSIMFATSYSLYL 187
Cdd:PRK08375  349 TYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVeagQWLVLAVLLASslLALLYFLRIWYRA 428

                         170       180
                  ....*....|....*....|....*....
gi 2161959099 188 FWSSQREYLPSHMKSLSPTMTREHILLAL 216
Cdd:PRK08375  429 FFGPPPPGSEAPKQEAPLGMLAPSLALAL 457
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-182 6.20e-09

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 55.53  E-value: 6.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099   1 PVAGSMILAGTLLKLGGYGLLRTSSMIHES--FHPLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAAT 78
Cdd:PRK08676  237 PSVVSALLSGTVLNIGIYGILRLSALLRQSgaAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  79 MIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLI 158
Cdd:PRK08676  317 GIGTPLALFWMLFHMLAHSLVKSGLFFSAGILHRQYRSDRFDRIFDVFRLQPVAAWGVILGSAAIIGMPPFPLFLSKFFI 396

                         170       180
                  ....*....|....*....|....
gi 2161959099 159 LLSVFKWAPYSILLAGLSIMFATS 182
Cdd:PRK08676  397 LLQLGGISVWLVLAVLLLLLLAAS 420
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-174 2.98e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 50.50  E-value: 2.98e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  33 PLAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYE 112
Cdd:PRK12662  277 PFNNVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSISY 356

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2161959099 113 RTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFK---WAPYSILLAG 174
Cdd:PRK12662  357 HFGTTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKsnaWIGLVVLLVG 421
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 38-190 5.13e-07

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 49.77  E-value: 5.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSR 117
Cdd:PRK08377  276 VIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVFHMINHAIVKALLFLAVGYVGITLGGT 355

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2161959099 118 TMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFigellillsvfkWAPYSILLAGLSIMFATSYSLYLFWS 190
Cdd:PRK08377  356 EIEKFEGLGKRMPLTALALTIGALSTVGIPLFNVF------------WSKFRIILAGLSAGYTWPVALVLGAS 416
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 56-206 5.15e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 46.50  E-value: 5.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  56 QTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAW 135
Cdd:PRK12665  294 QSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIYYVAHHITVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVL 373

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2161959099 136 WLLATMLNMALPPSTNFIGELLIL---LSVFKWAPYSILLAGLSIMFATSYSL-----YLFWSSQREYLPSHMKSLSPT 206
Cdd:PRK12665  374 FFVPALNLGGIPPFSGFIGKVALLeagAEDGTWLAWALVAGGVVTSLLTLYAVarvwtKAFWRAREDAPEGHLADARPA 452
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-114 6.15e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 46.48  E-value: 6.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  34 LAPPLIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIkspwsvsgAMLLMISHGLVSSALFCLANTAYER 113
Cdd:PRK07234  244 LDLIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLGFILAAPLV--------GGLYALAHGLVKSTLFLCAGALPSR 315


                  .
gi 2161959099 114 T 114
Cdd:PRK07234  316 N 316
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 38-216 1.07e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 45.91  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKspwSVSGAMLLMISHGLVSSALFCLANTAYERTNSR 117
Cdd:COG1009   278 VAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTR 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 118 TMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAPYSILLAGLSI---MFATSYSLYL----FWS 190
Cdd:COG1009   355 DIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLLAVALlgaFLTAFYSFRLfflvFFG 434

                         170       180
                  ....*....|....*....|....*.
gi 2161959099 191 SQREYLPSHMKSLSPTMTREHILLAL 216
Cdd:COG1009   435 KPRPKTPKHPHESPWLMTLPLVVLAV 460
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
38-158 1.61e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 45.02  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFAMFGVVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSR 117
Cdd:PRK06277  269 LIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTS 348

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2161959099 118 TMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLI 158
Cdd:PRK06277  349 NLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLML 389
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 55-189 1.77e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 45.30  E-value: 1.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  55 RQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAA 134
Cdd:PRK12644  287 RQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAMLLAHALFKAALFLVVGIIDHSTGTRDIRKLSGLGRRQPVLAV 366

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161959099 135 WWLLATMLNMALPPSTNFIG-----ELLILLSVFKWAPySILLAGLSI--MFATSYSLYLFW 189
Cdd:PRK12644  367 VAALAAASMAGLPPLLGFVAkeaalEAVLHDGALGPAG-PVVLAGIVLgsILTVAYSLRFLW 427
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 24-158 4.07e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 44.22  E-value: 4.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  24 SSMIHESFHPLapPLIIFAMFG---VVASALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVS 100
Cdd:PRK08668  260 SEFGTYRGVPL--FNYILAWLGnisIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFK 337

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2161959099 101 SALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLI 158
Cdd:PRK08668  338 GLFFLIFAAVIYRTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLI 395
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 23-218 1.31e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 42.24  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  23 TSSMIHESFHPLAPPLIIFAMFGVVAsallcsrQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSA 102
Cdd:PRK07691  270 DTSFTHYLILILALLTIIFGVIGAVA-------YFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGAIYYLIHDMIVKAA 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 103 LFCLANTAYERTNSrTMIVLQGSQIILPLAAAWWLLATMLNMA-LPPSTNFIGELLILLSVFKWAPYSILLAGLSIMFAT 181
Cdd:PRK07691  343 LFLLIGIMIKITGT-TDLKKMGGLIKRYPVLGWMFFIAALSLAgIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLV 421

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2161959099 182 SYS-----LYLFWSSQREYLPSHMKSLSPTMTREHILLALHI 218
Cdd:PRK07691  422 LYSvikifLKGFWGEPKGYDLNNKVPVKKLLLPAVVLVAITI 463
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 55-164 2.12e-04

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 41.64  E-value: 2.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  55 RQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALF-CLANTAYERTNSRTMIVLQG-SQIILPLA 132
Cdd:COG1007   289 AQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFaVILLLSRKGGEAEEIEDLAGlARRSPLLA 368

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2161959099 133 AAwwLLATMLNMA-LPPSTNFIGELLILLSVFK 164
Cdd:COG1007   369 LA--MTIFLLSLAgIPPTAGFFGKFYVFSAAVE 399
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 39-164 3.10e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 41.25  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  39 IIFAMFGVVASAllcsRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSG-----------AMLLMISHGLVSSALFCLA 107
Cdd:PRK08667  278 SISALLGVIYAL----KEHDLKGLLAYSSIENIGIILMGIGLYVIFGVYGldtlallalggALFHSLNHALFKSLLFLTA 353

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2161959099 108 NTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFK 164
Cdd:PRK08667  354 GSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELLLYESFFQ 410
PRK12648 PRK12648
putative monovalent cation/H+ antiporter subunit A; Reviewed
 56-185 3.74e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237157 [Multi-domain]  Cd Length: 948  Bit Score: 41.33  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  56 QTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAW 135
Cdd:PRK12648  292 QHDLKGLLAYSTISHLGLITLLLGLGSPLAAVAAIFHIINHATFKASLFMAAGIIDHETGTRDMRRLSGLRRLMPITATL 371

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099 136 WLLATmLNMALPPSTN-------FIGELL--ILLSVFKWA-PYSILLAGlsiMFATSYSL 185
Cdd:PRK12648  372 AMVAA-AAMAGVPLLNgflskemFFAETLdtHLLGSLDWLlPVAATLAG---AFSVAYSL 427
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
28-104 4.64e-04

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 40.57  E-value: 4.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  28 HESFHPLAPPLIIFAMFGVVAS----ALLCSRQTDLKSLIAFSSVSHMGLVVAATMIKSPWSVSGAMLLMISHGLVSSAL 103
Cdd:PRK05777  259 VVAFGGLSEDWQQVLAIIAIASmlvgNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMTLGA 338


                  .
gi 2161959099 104 F 104
Cdd:PRK05777  339 F 339
PRK08042 PRK08042
formate hydrogenlyase subunit 3; Reviewed
 88-164 4.25e-03

formate hydrogenlyase subunit 3; Reviewed


Pssm-ID: 181206 [Multi-domain]  Cd Length: 593  Bit Score: 37.88  E-value: 4.25e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2161959099  88 GAMLLMISHGLVSSALFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFK 164
Cdd:PRK08042  309 GGLYHLLNHSLFKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEWVIYQSFFK 385
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 38-167 5.20e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 37.38  E-value: 5.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161959099  38 LIIFA---MFGVVASALLcsrQTDLKSLIAFSSVSH-----MGLVVAATMIKSPWSVS-------GAMLLMISHGLVSSA 102
Cdd:PRK08376  290 IIILGcltMFVGVAMAVV---QKDVKRLLAYHSVSQigymlLGLGVGLAALGDPAMASygeialaGGIYHIVNHALYKAL 366

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2161959099 103 LFCLANTAYERTNSRTMIVLQGSQIILPLAAAWWLLATMLNMALPPSTNFIGELLILLSVFKWAP 167
Cdd:PRK08376  367 LFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFNP 431
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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