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Conserved domains on  [gi|2260768966|gb|UST29344|]
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serine--glyoxylate aminotransferase, partial [Indurgia sp. HBG05121]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02409 super family cl30752
serine--glyoxylate aminotransaminase
 1-102 7.60e-73

serine--glyoxylate aminotransaminase


The actual alignment was detected with superfamily member PLN02409:

Pssm-ID: 178031 [Multi-domain]  Cd Length: 401  Bit Score: 221.17  E-value: 7.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVFFDWNDYLKFYKMGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNRL 80
Cdd:PLN02409  202 ALSLPTGLGIVCASPKALEASKTAKSPRVFFDWADYLKFYKLGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHARL 281

                          90       100
                  ....*....|....*....|..
gi 2260768966  81 GKATRLAVEAWGLKNCTQKEEW 102
Cdd:PLN02409  282 GEATRLAVEAWGLKLCTKKPEW 303
 
Name Accession Description Interval E-value
PLN02409 PLN02409
serine--glyoxylate aminotransaminase
 1-102 7.60e-73

serine--glyoxylate aminotransaminase


Pssm-ID: 178031 [Multi-domain]  Cd Length: 401  Bit Score: 221.17  E-value: 7.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVFFDWNDYLKFYKMGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNRL 80
Cdd:PLN02409  202 ALSLPTGLGIVCASPKALEASKTAKSPRVFFDWADYLKFYKLGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHARL 281

                          90       100
                  ....*....|....*....|..
gi 2260768966  81 GKATRLAVEAWGLKNCTQKEEW 102
Cdd:PLN02409  282 GEATRLAVEAWGLKLCTKKPEW 303
AGAT_like cd06451
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ...
 1-102 1.33e-43

Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.


Pssm-ID: 99744 [Multi-domain]  Cd Length: 356  Bit Score: 144.74  E-value: 1.33e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVF-FDWNDYLKFYKMGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNR 79
Cdd:cd06451   187 ALGAPPGLGPIAFSERALERIKKKTKPKGFyFDLLLLLKYWGEGYSYPHTPPVNLLYALREALDLILEEGLENRWARHRR 266

                          90       100
                  ....*....|....*....|...
gi 2260768966  80 LGKATRLAVEAWGLKNCTQKEEW 102
Cdd:cd06451   267 LAKALREGLEALGLKLLAKPELR 289
PucG COG0075
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ...
 1-94 7.25e-41

Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis


Pssm-ID: 439845 [Multi-domain]  Cd Length: 376  Bit Score: 137.91  E-value: 7.25e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVFFDWNDYLKFYKMGtYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNRL 80
Cdd:COG0075   188 CLMLPPGLAFVAVSERALEAIEARKLPSYYLDLKLWLKYWEKG-QTPYTPPVSLLYALREALDLILEEGLENRFARHRRL 266

                          90
                  ....*....|....
gi 2260768966  81 GKATRLAVEAWGLK 94
Cdd:COG0075   267 AEALRAGLEALGLE 280
Aminotran_5 pfam00266
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ...
 5-80 2.61e-04

Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.


Pssm-ID: 425567 [Multi-domain]  Cd Length: 368  Bit Score: 38.38  E-value: 2.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   5 PTGMGIVCASPKALEASKTA--NSVRVFFDWNDYLKFYkmGTYWPY---TPSIQLLYGLRAALDLIFEEGLENVIARHNR 79
Cdd:pfam00266 205 PTGIGVLYGRRDLLEKMPPLlgGGGMIETVSLQESTFA--DAPWKFeagTPNIAGIIGLGAALEYLSEIGLEAIEKHEHE 282


                  .
gi 2260768966  80 L 80
Cdd:pfam00266 283 L 283
 
Name Accession Description Interval E-value
PLN02409 PLN02409
serine--glyoxylate aminotransaminase
 1-102 7.60e-73

serine--glyoxylate aminotransaminase


Pssm-ID: 178031 [Multi-domain]  Cd Length: 401  Bit Score: 221.17  E-value: 7.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVFFDWNDYLKFYKMGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNRL 80
Cdd:PLN02409  202 ALSLPTGLGIVCASPKALEASKTAKSPRVFFDWADYLKFYKLGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHARL 281

                          90       100
                  ....*....|....*....|..
gi 2260768966  81 GKATRLAVEAWGLKNCTQKEEW 102
Cdd:PLN02409  282 GEATRLAVEAWGLKLCTKKPEW 303
AGAT_like cd06451
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ...
 1-102 1.33e-43

Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.


Pssm-ID: 99744 [Multi-domain]  Cd Length: 356  Bit Score: 144.74  E-value: 1.33e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVF-FDWNDYLKFYKMGTYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNR 79
Cdd:cd06451   187 ALGAPPGLGPIAFSERALERIKKKTKPKGFyFDLLLLLKYWGEGYSYPHTPPVNLLYALREALDLILEEGLENRWARHRR 266

                          90       100
                  ....*....|....*....|...
gi 2260768966  80 LGKATRLAVEAWGLKNCTQKEEW 102
Cdd:cd06451   267 LAKALREGLEALGLKLLAKPELR 289
PucG COG0075
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ...
 1-94 7.25e-41

Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis


Pssm-ID: 439845 [Multi-domain]  Cd Length: 376  Bit Score: 137.91  E-value: 7.25e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   1 ALSLPTGMGIVCASPKALEASKTANSVRVFFDWNDYLKFYKMGtYWPYTPSIQLLYGLRAALDLIFEEGLENVIARHNRL 80
Cdd:COG0075   188 CLMLPPGLAFVAVSERALEAIEARKLPSYYLDLKLWLKYWEKG-QTPYTPPVSLLYALREALDLILEEGLENRFARHRRL 266

                          90
                  ....*....|....
gi 2260768966  81 GKATRLAVEAWGLK 94
Cdd:COG0075   267 AEALRAGLEALGLE 280
PRK13479 PRK13479
2-aminoethylphosphonate--pyruvate transaminase; Provisional
 7-79 1.00e-04

2-aminoethylphosphonate--pyruvate transaminase; Provisional


Pssm-ID: 184076 [Multi-domain]  Cd Length: 368  Bit Score: 39.51  E-value: 1.00e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2260768966   7 GMGIVCASPKALEASKtANSVRVFFDWNDYLKFYKMGTYWPYTPSIQLLYGLRAALDLIFEEGleNVIARHNR 79
Cdd:PRK13479  200 GFGFVIARRSELEACK-GNSRSLSLDLYDQWAYMEKTGQWRFTPPTHVVAAFYQALLELEEEG--GVPARGAR 269
Aminotran_5 pfam00266
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ...
 5-80 2.61e-04

Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.


Pssm-ID: 425567 [Multi-domain]  Cd Length: 368  Bit Score: 38.38  E-value: 2.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2260768966   5 PTGMGIVCASPKALEASKTA--NSVRVFFDWNDYLKFYkmGTYWPY---TPSIQLLYGLRAALDLIFEEGLENVIARHNR 79
Cdd:pfam00266 205 PTGIGVLYGRRDLLEKMPPLlgGGGMIETVSLQESTFA--DAPWKFeagTPNIAGIIGLGAALEYLSEIGLEAIEKHEHE 282


                  .
gi 2260768966  80 L 80
Cdd:pfam00266 283 L 283
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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