NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2267398408|gb|UTE81747|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Propithecus edwardsi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 1.30e-154

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 437.74  E-value: 1.30e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330
                  ....*....|....
gi 2267398408 321 KFTLFLSPLITLST 334
Cdd:MTH00105  321 KPMTLLPTLIILST 334
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 1.30e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 437.74  E-value: 1.30e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330
                  ....*....|....
gi 2267398408 321 KFTLFLSPLITLST 334
Cdd:MTH00105  321 KPMTLLPTLIILST 334
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-297 1.98e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 100.41  E-value: 1.98e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  13 IFTGTMLTMISSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHN 91
Cdd:TIGR01770 111 ALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLL 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  92 LLTTLT------------IIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSM-------NTN 152
Cdd:TIGR01770 191 FLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQI 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 153 ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLML----TITLFTML------NVN 222
Cdd:TIGR01770 271 FLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGVLsllrsyKDE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2267398408 223 TSTTTLTLSILWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:TIGR01770 351 WIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 3.81e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 99.81  E-value: 3.81e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  18 MLTMISS-HWLLIWMGLEMNMLAIIpILA--KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT 94
Cdd:COG1007   115 MMLMASAnDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALA 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  95 TLT------------IIIALTMKLGMTPFHFWIPEVTQG----VTL-------TAGMLLLtwqklapISIMLQIYPSMNT 151
Cdd:COG1007   194 AGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAAL-------LRLLVEAFPGLAA 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 152 NILLTFALLSAL---VGGWGGLNQTQLRKILAYSSITHMGWM-VAVLTFCP---SLTILNLLIYLMLTITLFTMLNVNTS 224
Cdd:COG1007   267 DWQLLLAVLAVLsmtVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPlgvSAALFYLLAYLFMNLGAFAVILLLSR 346

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2267398408 225 TTTLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIY 298
Cdd:COG1007   347 KGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 2.17e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 95.07  E-value: 2.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  23 SSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT------- 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  95 ----TLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLL-TWQKLAPISIMLQIYPSMN-----TNILLTFALLSALV 164
Cdd:pfam00361  81 llllFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 165 GGWGGLNQTQLRKILAYSSITHMGWMVAVL----TFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSI-----LWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIrdyggLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2267398408 236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 1.30e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 437.74  E-value: 1.30e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330
                  ....*....|....
gi 2267398408 321 KFTLFLSPLITLST 334
Cdd:MTH00105  321 KPMTLLPTLIILST 334
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-334 3.90e-114

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 334.85  E-value: 3.90e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSmNTNILLTFALL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330
                  ....*....|....
gi 2267398408 321 KFTLFLSPLITLST 334
Cdd:MTH00135  320 QLTLPLAISTTATL 333
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-334 1.73e-105

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 313.01  E-value: 1.73e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLqPT 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                         330
                  ....*....|....
gi 2267398408 321 KFTLFLSPLITLST 334
Cdd:MTH00070  320 KTNNLLSLTIILSL 333
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-334 1.01e-104

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 310.99  E-value: 1.01e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330
                  ....*....|....
gi 2267398408 321 KFTLfLSPLITLST 334
Cdd:MTH00112  321 KNTL-TATLTTLST 333
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-307 5.35e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 242.91  E-value: 5.35e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPT 307
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-327 1.39e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 241.80  E-value: 1.39e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320


                  ....*..
gi 2267398408 321 KFTLFLS 327
Cdd:MTH00200  321 SNLLVGL 327
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-333 1.58e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.85  E-value: 1.58e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  81 TgqwnvtNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIypsMNTNILLTFALL 160
Cdd:MTH00160   82 L------MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 161 SALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312

                         330
                  ....*....|...
gi 2267398408 321 KFTLFLSPLITLS 333
Cdd:MTH00160  313 LILNFLSFISLFG 325
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-315 1.82e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 168.53  E-value: 1.82e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  10 ITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTni 89
Cdd:MTH00144   10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM-- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  90 hnllttLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNT-NILLTFALLSALVGGWG 168
Cdd:MTH00144   88 ------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 169 GLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILwNKNPTITLMILTSL 248
Cdd:MTH00144  162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLL 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2267398408 249 LSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKW 315
Cdd:MTH00144  241 LSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 11-329 2.96e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 157.63  E-value: 2.96e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  11 TTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTnih 90
Cdd:MTH00011   13 STMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLKNI--- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  91 nllTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALLSALVGGWGGL 170
Cdd:MTH00011   90 ---TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGM 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 171 NQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTITLMILTSLLS 250
Cdd:MTH00011  167 NQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLS 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2267398408 251 LGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYStSLTMFPTSNNMKMKWQLQPTKFTLFLSPL 329
Cdd:MTH00011  247 LGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLKSAPYEPKTKILISMCTL 324
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-329 4.01e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 135.96  E-value: 4.01e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  12 TIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMytgqwnvTNIHN 91
Cdd:MTH00197    6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFS-------NLYLS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  92 LLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNtnILLTFALLSALVGGWGGLN 171
Cdd:MTH00197   79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFM--GLLICSVLSSLIGGIGGMN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 172 QTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTITLMILTSLLSL 251
Cdd:MTH00197  157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2267398408 252 GGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPTKFTLFLSPL 329
Cdd:MTH00197  237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMML 314
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-298 5.23e-27

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 110.88  E-value: 5.23e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   8 PIITTIFTGTMLTMISS-HWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWN 85
Cdd:MTH00199  100 PILILIVALGSLLLVSSiNWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETS 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  86 VTNIHNLLTT----LTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSmnTNILLTFALLS 161
Cdd:MTH00199  180 IQGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPV--TNVVLICAVLS 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 162 ALVGGWGGLNQTQLRKILAYSSITHMG---WMVAVLTFCP-SLTILNLLIYLMLTITLFT-MLNVNTSTTTLTLSI-LWN 235
Cdd:MTH00199  258 IIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSiILSLKLTKGLIVEVSgLSR 337

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2267398408 236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIY 298
Cdd:MTH00199  338 KNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-297 1.98e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 100.41  E-value: 1.98e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  13 IFTGTMLTMISSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHN 91
Cdd:TIGR01770 111 ALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLL 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  92 LLTTLT------------IIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSM-------NTN 152
Cdd:TIGR01770 191 FLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQI 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 153 ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLML----TITLFTML------NVN 222
Cdd:TIGR01770 271 FLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGVLsllrsyKDE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2267398408 223 TSTTTLTLSILWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:TIGR01770 351 WIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 3.81e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 99.81  E-value: 3.81e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  18 MLTMISS-HWLLIWMGLEMNMLAIIpILA--KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT 94
Cdd:COG1007   115 MMLMASAnDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALA 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  95 TLT------------IIIALTMKLGMTPFHFWIPEVTQG----VTL-------TAGMLLLtwqklapISIMLQIYPSMNT 151
Cdd:COG1007   194 AGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAAL-------LRLLVEAFPGLAA 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 152 NILLTFALLSAL---VGGWGGLNQTQLRKILAYSSITHMGWM-VAVLTFCP---SLTILNLLIYLMLTITLFTMLNVNTS 224
Cdd:COG1007   267 DWQLLLAVLAVLsmtVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPlgvSAALFYLLAYLFMNLGAFAVILLLSR 346

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2267398408 225 TTTLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIY 298
Cdd:COG1007   347 KGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-297 6.06e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 98.18  E-value: 6.06e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  16 GTMLTMISSHWLLIWMGLEMNMLAI-IPILAKKTNPRSTEAATKYFLTQATASMLLMMTIV-------------INAMYT 81
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  82 GQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPsmNTNILLTFALLS 161
Cdd:MTH00196   85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 162 ALVGGWGGLNQTQLRKILAYSSITHMG---WMVAVLTF-CPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSI--LWN 235
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFeSIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFsgLSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2267398408 236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 2.17e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 95.07  E-value: 2.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  23 SSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT------- 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  95 ----TLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLL-TWQKLAPISIMLQIYPSMN-----TNILLTFALLSALV 164
Cdd:pfam00361  81 llllFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 165 GGWGGLNQTQLRKILAYSSITHMGWMVAVL----TFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSI-----LWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIrdyggLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2267398408 236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-332 1.53e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 92.19  E-value: 1.53e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  15 TGTMLTMISS-HWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNL 92
Cdd:PRK05777  113 LLGMMVMVSAnDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  93 LTTLT------------IIIALTMKLGMTPFHFWIPEVTQG-----------VTLTAGM-LLLTWQKLAPISIMLQIYPs 148
Cdd:PRK05777  193 LADGSgnsllllfglvfLLVGLAFKLSAVPFHMWTPDVYEGaptpvtaflatAPKIAAFaVLLRLLVVAFGGLSEDWQQ- 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 149 mntnILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWM----VAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTS 224
Cdd:PRK05777  272 ----VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglAAGTAEGYSAVLFYLLAYLFMTLGAFGVISLLRR 347

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 225 TTTLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYs 299
Cdd:PRK05777  348 KGGEAESIsdfagLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIK- 426

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 2267398408 300 tslTMF--PTSNNMKMKWQLQPTKFTLFLSPLITL 332
Cdd:PRK05777  427 ---LMYfdEPPRDAPVNWPLSAGGAVLSVSALLVL 458
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-301 3.51e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 72.87  E-value: 3.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  15 TGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT 94
Cdd:COG0651   118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLA 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  95 TLT----------IIIALTMKLGMTPFHFWIPE-----------VTQGVTLTAGMLLLtwqklapISIMLQIYPSMNTN- 152
Cdd:COG0651   198 ELDpglllaafalLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVYAI-------LRVLTLLFGADPALf 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 153 ---ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYL---MLTITLFTMLNVNTSTT 226
Cdd:COG0651   271 lgtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhALAKALLFLAAGAIERA 350

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 227 TLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTS 301
Cdd:COG0651   351 TGTRDLdklggLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-219 1.44e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 68.35  E-value: 1.44e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  16 GTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRST---------EAATKYFLTQATASMLLMMTIVINAMYTGQ--- 83
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  84 --------WNVTNI---HNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYpsMNTN 152
Cdd:MTH00198  280 lgtilsatLETTNIelrQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLV--ITSK 357

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2267398408 153 ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILN----LLIYLMLTITLFTML 219
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQAswtyAVTYLVSALASFTVI 428
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 2.70e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 58.17  E-value: 2.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  55 AATKYFLTQATASMLLMMTIVINAMYTGQWNvTNIHNLLTT-----------LTIIIALTMKLGMTPFHFWIPEV----- 118
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALT-FDIAELAAAplpltaqlllfLAFFIAFAVKVPMFPFHTWLPDAhveap 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 119 TQGVTLTAGMLLltwqKLAP---ISIMLQIYP---SMNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVA 192
Cdd:COG1008   241 TAGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-297 4.23e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 54.67  E-value: 4.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   9 IITTIFTGTMLTMISSHWLLIWMGLEMnmLAIIPILAK---KTNPRSTEAATKYFLTQATAS-MLLMMTIVINAMYTGQW 84
Cdd:PRK02504  115 ILLTATLGGMFLSGATELVMIFISLET--LSIASYLLTgymKRDPRSNEAALKYLLIGAASSaIFLYGSSLLYGLSGGST 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  85 NVTNIHNLLT---TLTIIIALTM-------KLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLA----PISIMLQIYPSMN 150
Cdd:PRK02504  193 QLSAIALALItspSLGLALALVFviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFD 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 151 TNILLTF---ALLSALVGGWGGLNQTQLRKILAYSSITHMGW----MVAVLTFCPSLTILNLLIYLMLT------ITLFT 217
Cdd:PRK02504  273 EQWKLLFtalAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvmigLVAGTEAGYASMVFYLLAYLFMNlgafacVILFS 352

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 218 MLNVNTSTTTLTLsiLWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:PRK02504  353 LRTGTDQISDYAG--LYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVI 430
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-334 4.52e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 48.79  E-value: 4.52e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2267398408 291 YFYMRLIYSTSLTMFPTSNNMKMKWQLQPTKFTLFLSPLITLST 334
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSI 44
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 48-194 2.70e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 52.08  E-value: 2.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  48 TNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNI---------HNLLTTLTIII---ALTmKLGMTPFHFWI 115
Cdd:COG1009   156 EKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELlaaaptilsSPLLTLILLLLllgAFG-KSAQFPLHFWL 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 116 PEVTQGVT-----------LTAGMLLLTwqKLAPISIMLQIYpsmnTNILLTFALLSALVGGWGGLNQTQLRKILAYSSI 184
Cdd:COG1009   235 PDAMEGPTpvsallhaatmVKAGVYLLA--RLSPLFALSPVW----LTVVAIIGAITALFAALIALAQTDIKRVLAYSTV 308

                         170
                  ....*....|
gi 2267398408 185 THMGWMVAVL 194
Cdd:COG1009   309 SQLGYMFLAL 318
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-191 2.80e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 51.86  E-value: 2.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  55 AATKYFLTQATASMLLMMTIVINAMYTG---------QWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEV-TQGVTL 124
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGGgtfdllellNLPLPFGVQTWLFLAFFIAFAVKVPLFPLHTWLPDAhVEAPTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2267398408 125 TAGMLLLTWQKLAPISIM---LQIYPS---MNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMV 191
Cdd:TIGR01972 237 GSVILAGVLLKMGTYGFLrfnLPLFPDaslYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 7.62e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 50.59  E-value: 7.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  55 AATKYFLTQATASmlLMMTIVINAMYTGQWNVT---NIHNLLTT-----------LTIIIALTMKLGMTPFHFWIPEV-- 118
Cdd:PRK05846  162 AATKFFLYTLLGS--LLMLVAIIYLVVVYYNATgtfDIADLLNLplppgvqywlfLAFFIAFAVKMPMFPLHTWLPDAhv 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 119 ---TQGVTLTAGMLLltwqKLAP---ISIMLQIYPSMNTN---ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGW 189
Cdd:PRK05846  240 qapTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGF 315


                  ..
gi 2267398408 190 MV 191
Cdd:PRK05846  316 VT 317
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-210 1.24e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 49.88  E-value: 1.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  33 LEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLL--------TTLTIIIALTM 104
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALaenptvvtAFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 105 KLGMTPFHFWIPEvTQGVTLTAGMLLL--TWQKlAPISIMLQIYPSMNT----------NILLTFALLSALVGGWGGLNQ 172
Cdd:PRK08375  215 KAAVFPLHTWLPR-AYPAAPPVVTALLsgLVTK-VAVYALIRIYFTVFGgdfrfalglgWLLAVLALLSMLVGSLAALGQ 292

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2267398408 173 TQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLM 210
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLL 330
PRK12650 PRK12650
DUF4040 family protein;
9-194 2.02e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 49.66  E-value: 2.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408   9 IITTIFTGTMLTMI-SSHWLLIWMGLEMNMLAIIPILAKkTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGqwnVT 87
Cdd:PRK12650  114 LLMTAFMAAMLLLVlADDVVVLFVAWELVSLASFFLIAR-SGSGGEAGSIRTLILTFFGGLTLLAAVAIAATQTG---TT 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  88 NIHNLL--------TTLTIIIALTM------KLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTN- 152
Cdd:PRK12650  190 SLSGILhsdvwaekPGLTTVVAVLIavaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVa 269

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2267398408 153 ----ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVAVL 194
Cdd:PRK12650  270 vwnwLLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-188 7.36e-06

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 47.72  E-value: 7.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  55 AATKYFLTQATASMLLMMTIVINAMYTGQ--WNVTNIHN--------LLTTLTIIIALTMKLGMTPFHFWIP----EVTQ 120
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAksyplaleLLLYAGFLIAFGVKLPIFPLHTWLPdahgEASA 217

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2267398408 121 GVTLTAGMLLLTWQKLAPISIMLQIYPsmntNILLTFALLSALVGG----WGGLN---QTQLRKILAYSSITHMG 188
Cdd:PRK12561  218 PVSMILAGVLLKMGGYALIRFNVQMLP----DAHVYFAPALAILGVvniiYGALNafaQDNVKRRLAYSSVSHMG 288
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 54-190 1.95e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 46.24  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  54 EAATKYFLTQATASMLLMMTIvinAMYTGQWNVTNI----HNLLTTLTI---------IIALTMKLGMTPFHFWIPEVTQ 120
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMaylaVKMSENPTVvakialalfIAGLAMKSGAVPVHMWLPDAYP 248

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2267398408 121 GV--TLTAGMLLLTWQKLAPIS-IMLQIY-PSMNTN----ILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWM 190
Cdd:PRK08376  249 AApsSISAMLLVIKQAGLYALArVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYM 326
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
27-190 3.99e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 45.08  E-value: 3.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  27 LLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTG----QWNVTNIHNL------LTTL 96
Cdd:PRK06473  130 LLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGassfDYEPLRSHTLplstqlLLLA 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  97 TIIIALTMKLGMTPFHFWIPEV-----TQGVTLTAGMLLltwqKLAPISIM---LQIYPSMNTNI---LLTFALLSALVG 165
Cdd:PRK06473  210 PILVGFGIKIPLVPFHTWLPDAhveasTPVSVLLAGVLL----KLGTYGLLrfgVGLFPEAWVYLapwLATWAVVSVLYG 285

                         170       180
                  ....*....|....*....|....*
gi 2267398408 166 GWGGLNQTQLRKILAYSSITHMGWM 190
Cdd:PRK06473  286 ASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
51-325 4.31e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 45.02  E-value: 4.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  51 RSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLTT-----------LTIIIALTMKLGMTPFHFWIPEVT 119
Cdd:PRK06277  147 EAYKAALKYMILGNVAGSILLLGIGFLLASTGTLNITDIHNALLVnptspviygglLLLIFGLLYGSGLPPFHTIKSDIY 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 120 QGVTLTAGMLLLTWQKLAPISIMLQIY---------PSMNTnILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWM 190
Cdd:PRK06277  227 AKAKPFGSALLQTFSKFVLVALMLVIFklfgglsyfPSAQG-VLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYV 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 191 VAVLTFCPSLTI-------LNLLIYL-MLTITLFTMLNVNTSTTTLTLSILWNKNPTITLMILTSLLSLGGLPPLTGFLP 262
Cdd:PRK06277  306 AAGLALGTPLGIvagifhaINHVIYKsALFLGAGIVSYRTKTSNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQS 385

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2267398408 263 KWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPTKFTLF 325
Cdd:PRK06277  386 KLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYLIYLKPKPEELEYKNKKVPKYAVFSLA 448
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-210 1.90e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 43.20  E-value: 1.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  17 TMLTMISSHWLLIWMGLEMNML---AIIPILAKKTNprsTEAATKYFLTQATA------SMLLMMTIVINAMYTGQWNVT 87
Cdd:PRK08676  115 ITFAFFSDNLALFWIFAELTTVfsaMLIAILSAREN---IDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWT 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  88 NIHNL----------LTTLTIIIALTMKLGMTPFHFWIPE-----------VTQGVTLTAGMLLLTwqKLAPISIMLQIY 146
Cdd:PRK08676  192 ELAAHasllspsvlgASFLFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGIYGIL--RLSALLRQSGAA 269

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2267398408 147 PSMnTNILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYLM 210
Cdd:PRK08676  270 EQF-SNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 99-299 8.58e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 41.11  E-value: 8.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  99 IIALTMKLGMTPFHFWIPE-----------------VTQGVTLTAGMLLLTWQklapISIMLQIYPSMNTNILLTFALLS 161
Cdd:PRK12667  230 LWAFTIKAAIFPNHFWLPDahpaapspvsamlsglvVNVGAYAIIRFLYTIFG----ISPSLIDFRAALSPILIILGAVS 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 162 ALVGGWGGLNQTQLRKILAYSSITHMGWMVAVLTFCPSLTILNLLIYL--------MLTITLFTMLNVNTSTTTLTLSIL 233
Cdd:PRK12667  306 AIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGL 385

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2267398408 234 WNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYS 299
Cdd:PRK12667  386 GRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 96-211 1.77e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 40.04  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  96 LTIIIALTMKLGMTPFHFWIPEV-----TQGVTLTAGMLLltwqKLAP---ISIMLQIYPSMN---TNILLTFALLSALV 164
Cdd:MTH00217  210 LGFFLSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGygfIRFSWPLLPEASeyfSPLIQTLSLLAIIY 285

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2267398408 165 GGWGGLNQTQLRKILAYSSITHMGwMVAVLTFCPSLTILNLLIYLML 211
Cdd:MTH00217  286 GSLTTCRQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
ndhB CHL00049
NADH dehydrogenase subunit 2
 47-297 3.27e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 39.22  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  47 KTNPRSTEAATKYFLTQATASMLL----------------MMTIVINAMYTGQWNVTNIhnLLTTLTIIIALTMKLGMTP 110
Cdd:CHL00049  155 KKDVRSNEATMKYLLMGGASSSILvygfswlyglsggeieLQEIVNGLINTQMYNSPGI--SIALIFITVGIGFKLSLAP 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 111 FHFWIPEVTQG----------VTLTAGMLLLTwqklapISIMLQIYPSMNT---NILLTFALLSALVGGWGGLNQTQLRK 177
Cdd:CHL00049  233 FHQWTPDVYEGsptpvvaflsVTSKVAASALA------TRIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKR 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 178 ILAYSSITHMGW-MVAVLTFCPSLTILNLLIYLMLTItlftMLNVNTSTTTLTLSI------------LWNKNPTITLMI 244
Cdd:CHL00049  307 MLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYI----FMNLGTFACIVLFGLrtgtdnirdyagLYTKDPFLALSL 382

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2267398408 245 LTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:CHL00049  383 ALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 13-191 3.58e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 39.14  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  13 IFTGTML-TMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFL------TQATASMLLMM----TIVINAMYT 81
Cdd:PRK06458  116 LFLFTMLlALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYanaaTVMGDGEMA 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  82 GQWNVTNIHN-----LLTTLTIIIALT---MKLGMTPFHFWIPE-----------VTQGVTLTAGMLLLTWQKlapISIM 142
Cdd:PRK06458  196 ILWTELLKHAslldpTLMKLAFVFLLIgfgTKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYY---ILID 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2267398408 143 LQIYPSMNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSITHMGWMV 191
Cdd:PRK06458  273 AAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIA 321
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
85-191 4.29e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 38.92  E-value: 4.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  85 NVTNIHNLLTTLTIIIALTMKLGMTPFHFWIP----EVTQGVTLTAGMLLLTWQKLAPISIMLQIYP---SMNTNILLTF 157
Cdd:PRK07363  198 NLSLNTQLILLTGLLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGLAII 277

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2267398408 158 ALLSALVGGWGGLNQTQLRKILAYSSITHMGWMV 191
Cdd:PRK07363  278 GTISVIYGALSAIAQKDIKRMVAYSSIGHMGYIL 311
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-194 6.04e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 38.40  E-value: 6.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 111 FHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYP-----SMNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSIT 185
Cdd:MTH00032  244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekaPLTLLIITIFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                  ....*....
gi 2267398408 186 HMGWMVAVL 194
Cdd:MTH00032  324 QLGYMVLII 332
PRK12668 PRK12668
Na(+)/H(+) antiporter subunit D;
50-192 7.10e-03

Na(+)/H(+) antiporter subunit D;


Pssm-ID: 237168 [Multi-domain]  Cd Length: 581  Bit Score: 38.34  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  50 PRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLTTLTIIIALTM--KLGMTPFHFWIPE------VTQG 121
Cdd:PRK12668  139 KAAVRAGFRYLLVHVLGGVLLLAGILLHYAETGSFAFGAIAGLGGTAAWLILIGFgvNAAFPPLHAWLPDaypeatVTGS 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 122 VTLTA---------------GMLLLTWqklapISIMLQIYPsmntnilLTFALLsalvggwgglnQTQLRKILAYSSITH 186
Cdd:PRK12668  219 VFLSAfttktavyalarafpGTELLIY-----IGAAMAVYG-------VFFALL-----------ENDLRRLLSYHIVSQ 275


                  ....*.
gi 2267398408 187 MGWMVA 192
Cdd:PRK12668  276 VGYMVA 281
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-315 8.38e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.54  E-value: 8.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408  98 IIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALLSALVggwgGLNQTQLRK 177
Cdd:MTH00091   63 QFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSYKN 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267398408 178 ILAYSSITHMGWMvaVLTFCPSLTILNLLIYLMLTITLFTMLNvntstttltlsilWNKNPTITLMILTSLLSLGGLPPL 257
Cdd:MTH00091  139 LLILSSTESFNWL--ILSFFFSFFNVFFLFFYYFLLMLFLIPK-------------FNNVNKLNFVSWETLLVFMNLPFS 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2267398408 258 TGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKW 315
Cdd:MTH00091  204 VTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH