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Conserved domains on  [gi|2289362908|gb|UVJ47958|]
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small phospoprotein [Vector p47832/Ins-Change]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HEV_ORF1 super family cl03597
Hepatitis E virus ORF-2 (Putative capsid protein); The Hepatitis E virus (HEV) genome is a ...
 13-122 2.84e-17

Hepatitis E virus ORF-2 (Putative capsid protein); The Hepatitis E virus (HEV) genome is a single-stranded, positive-sense RNA molecule of approximately 7.5 kb. Three open reading frames (ORF) were identified within the HEV genome: ORF1 encodes non-structural proteins, ORF2 encodes the putative structural protein(s), and ORF3 encodes a protein of unknown function. ORF2 contains a consensus signal peptide sequence at its amino terminus and a capsid-like region with a high content of basic amino acids similar to that seen with other virus capsid proteins.


The actual alignment was detected with superfamily member pfam02444:

Pssm-ID: 280583  Cd Length: 114  Bit Score: 71.70  E-value: 2.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289362908  13 PCALGLFCCCSSCFCLCCPRHRPASRLAAVVGGAAAVPAVVSGVTGLILSPSPSPIFIQPTPLPPMSYRNPGLELALDSH 92
Cdd:pfam02444   5 PCALGLFCCCSSCFCLCCPRHRPVSRLAAAVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRPGLDLVFANP 84

                          90       100       110
                  ....*....|....*....|....*....|
gi 2289362908  93 PAPSAPLGAISPSAPLLSHVVDLPQPGLRR 122
Cdd:pfam02444  85 PDHSAPLGVTRPSAPPLPHVVDLPQLGPRR 114
 
Name Accession Description Interval E-value
HEV_ORF1 pfam02444
Hepatitis E virus ORF-2 (Putative capsid protein); The Hepatitis E virus (HEV) genome is a ...
 13-122 2.84e-17

Hepatitis E virus ORF-2 (Putative capsid protein); The Hepatitis E virus (HEV) genome is a single-stranded, positive-sense RNA molecule of approximately 7.5 kb. Three open reading frames (ORF) were identified within the HEV genome: ORF1 encodes non-structural proteins, ORF2 encodes the putative structural protein(s), and ORF3 encodes a protein of unknown function. ORF2 contains a consensus signal peptide sequence at its amino terminus and a capsid-like region with a high content of basic amino acids similar to that seen with other virus capsid proteins.


Pssm-ID: 280583  Cd Length: 114  Bit Score: 71.70  E-value: 2.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289362908  13 PCALGLFCCCSSCFCLCCPRHRPASRLAAVVGGAAAVPAVVSGVTGLILSPSPSPIFIQPTPLPPMSYRNPGLELALDSH 92
Cdd:pfam02444   5 PCALGLFCCCSSCFCLCCPRHRPVSRLAAAVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRPGLDLVFANP 84

                          90       100       110
                  ....*....|....*....|....*....|
gi 2289362908  93 PAPSAPLGAISPSAPLLSHVVDLPQPGLRR 122
Cdd:pfam02444  85 PDHSAPLGVTRPSAPPLPHVVDLPQLGPRR 114
 
Name Accession Description Interval E-value
HEV_ORF1 pfam02444
Hepatitis E virus ORF-2 (Putative capsid protein); The Hepatitis E virus (HEV) genome is a ...
 13-122 2.84e-17

Hepatitis E virus ORF-2 (Putative capsid protein); The Hepatitis E virus (HEV) genome is a single-stranded, positive-sense RNA molecule of approximately 7.5 kb. Three open reading frames (ORF) were identified within the HEV genome: ORF1 encodes non-structural proteins, ORF2 encodes the putative structural protein(s), and ORF3 encodes a protein of unknown function. ORF2 contains a consensus signal peptide sequence at its amino terminus and a capsid-like region with a high content of basic amino acids similar to that seen with other virus capsid proteins.


Pssm-ID: 280583  Cd Length: 114  Bit Score: 71.70  E-value: 2.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289362908  13 PCALGLFCCCSSCFCLCCPRHRPASRLAAVVGGAAAVPAVVSGVTGLILSPSPSPIFIQPTPLPPMSYRNPGLELALDSH 92
Cdd:pfam02444   5 PCALGLFCCCSSCFCLCCPRHRPVSRLAAAVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRPGLDLVFANP 84

                          90       100       110
                  ....*....|....*....|....*....|
gi 2289362908  93 PAPSAPLGAISPSAPLLSHVVDLPQPGLRR 122
Cdd:pfam02444  85 PDHSAPLGVTRPSAPPLPHVVDLPQLGPRR 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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