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Conserved domains on  [gi|2309225273|gb|UXK54892|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Amazona farinosa farinosa]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 super family cl33352
NADH dehydrogenase subunit 2; Provisional
 1-170 8.30e-81

NADH dehydrogenase subunit 2; Provisional


The actual alignment was detected with superfamily member MTH00112:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 242.81  E-value: 8.30e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00112  161 STLIGGWGGL 170
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-170 8.30e-81

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 242.81  E-value: 8.30e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00112  161 STLIGGWGGL 170
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-163 7.39e-13

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 65.14  E-value: 7.39e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  10 TLSILLGTTITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLMLF-SSMINAWhTGQWDIT 87
Cdd:COG1007   108 LLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLA 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  88 QL--------THPP----ACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKL----PPTTLLLITSHSLNP 151
Cdd:COG1007   187 GIaaalaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAA 266

                         170
                  ....*....|..
gi 2309225273 152 TLLTTMSIMSIA 163
Cdd:COG1007   267 DWQLLLAVLAVL 278
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 11-136 1.32e-08

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 53.03  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  11 LSILLGTTITITSNHWAMAWAGLEINTLSI-IPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITQL 89
Cdd:TIGR01770 109 LFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDL 188

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2309225273  90 TH--------PPAC----LLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKL 136
Cdd:TIGR01770 189 LLflsngmlnISLLllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKI 247
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-170 2.17e-08

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 51.93  E-value: 2.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  23 SNHWAMAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITQL--THPPAC---- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  96 -----LLLTTAIATKLGLAPLHFWFPEVLQGSSLT-TALLLSTIMKLPP-----TTLLLITSHSLNPTLLTTMSIMSIAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160


                  ....*.
gi 2309225273 165 GGWMGL 170
Cdd:pfam00361 161 GSLAAL 166
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-170 8.30e-81

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 242.81  E-value: 8.30e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00112  161 STLIGGWGGL 170
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-170 2.88e-64

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 200.53  E-value: 2.88e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00070  161 STLIGGWGGL 170
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-170 9.69e-63

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 196.56  E-value: 9.69e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSlNPTLLTTMSIM 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00135  160 STLVGGWGGL 169
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-170 7.51e-59

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 186.59  E-value: 7.51e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00105  161 SILIGGWGGL 170
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-170 1.24e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 157.82  E-value: 1.24e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00200  161 SVLVGGWGGL 170
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 11-170 1.88e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 154.70  E-value: 1.88e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  11 LSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITQLT 90
Cdd:MTH00041   11 TSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  91 HPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIMSIALGGWMGL 170
Cdd:MTH00041   91 NTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGL 170
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-170 1.22e-28

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 107.99  E-value: 1.22e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWh 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 tgqwdITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLlitSHSLNPTLLTTMSIM 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILL---SYLINNNFIIIIIIL 152

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00160  153 SAIIGAIGGL 162
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-170 1.26e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 94.57  E-value: 1.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  13 ILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITqlthp 92
Cdd:MTH00144   13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM----- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  93 pacLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPttLLLITSHSLNPTLLTT---MSIMSIALGGWMG 169
Cdd:MTH00144   88 ---SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAP--LFLLSNFLDLYWLAYLlcvISVLSALVGSIGG 162


                  .
gi 2309225273 170 L 170
Cdd:MTH00144  163 L 163
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-170 4.09e-20

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 84.83  E-value: 4.09e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   1 MTPAAKLISTlSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSminawh 80
Cdd:MTH00011    4 TFPTMFLFSS-TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  81 TGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPTTLLLITSHSLNPTLLTTMSIM 160
Cdd:MTH00011   77 TMMWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAM 156

                         170
                  ....*....|
gi 2309225273 161 SIALGGWMGL 170
Cdd:MTH00011  157 SALAGGLGGM 166
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 11-170 1.12e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 78.18  E-value: 1.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  11 LSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTgqwditqLT 90
Cdd:MTH00197    5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  91 HPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLPPttLLLITSHSLNPTLLTTMSIMSIALGGWMGL 170
Cdd:MTH00197   78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGM 155
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-163 7.39e-13

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 65.14  E-value: 7.39e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  10 TLSILLGTTITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLMLF-SSMINAWhTGQWDIT 87
Cdd:COG1007   108 LLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLA 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  88 QL--------THPP----ACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKL----PPTTLLLITSHSLNP 151
Cdd:COG1007   187 GIaaalaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAA 266

                         170
                  ....*....|..
gi 2309225273 152 TLLTTMSIMSIA 163
Cdd:COG1007   267 DWQLLLAVLAVL 278
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-165 3.65e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 63.13  E-value: 3.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  13 ILLGTTITITSNHWAMAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQAAASTLMLFS-------------SMINA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  79 WHTGQWDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLppTTLLLITSHSLNPTLLTTMS 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKL--GIFSILVSIGLNVNILLIGG 159


                  ....*..
gi 2309225273 159 IMSIALG 165
Cdd:MTH00196  160 LFSLFVG 166
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-170 5.20e-10

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 57.14  E-value: 5.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  14 LLGTTITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLMLF-SSMINAWhTGQWDITQL-- 89
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgMSLLYGA-TGSLSFAGIak 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  90 ------THPP----ACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKL----PPTTLLLITSHSLNPT--- 152
Cdd:PRK05777  192 aladgsGNSLlllfGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqq 271

                         170
                  ....*....|....*...
gi 2309225273 153 LLTTMSIMSIALGGWMGL 170
Cdd:PRK05777  272 VLAIIAIASMLVGNLAAL 289
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 11-136 4.45e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 54.25  E-value: 4.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  11 LSILLGTTITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDI--- 86
Cdd:MTH00199  104 LIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqgi 183

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2309225273  87 -TQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKL 136
Cdd:MTH00199  184 nSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKI 234
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 11-136 1.32e-08

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 53.03  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  11 LSILLGTTITITSNHWAMAWAGLEINTLSI-IPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITQL 89
Cdd:TIGR01770 109 LFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDL 188

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2309225273  90 TH--------PPAC----LLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKL 136
Cdd:TIGR01770 189 LLflsngmlnISLLllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKI 247
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-170 2.17e-08

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 51.93  E-value: 2.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  23 SNHWAMAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITQL--THPPAC---- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  96 -----LLLTTAIATKLGLAPLHFWFPEVLQGSSLT-TALLLSTIMKLPP-----TTLLLITSHSLNPTLLTTMSIMSIAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160


                  ....*.
gi 2309225273 165 GGWMGL 170
Cdd:pfam00361 161 GSLAAL 166
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-170 3.97e-07

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 48.70  E-value: 3.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273   3 PAAKLISTLSILLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAI---------EAATKYFLVQAAASTLMLFS 73
Cdd:MTH00198  187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  74 SMINAWHTGQ--------------WDITQLTHPPACLLLTTAIATKLGLAPLHFWFPEVLQGSSLTTALLLSTIMKLppT 139
Cdd:MTH00198  267 CALYFGFTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--T 344

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2309225273 140 TLLLITSHSLNPTLLTTMSIMSIALGGWMGL 170
Cdd:MTH00198  345 VYILLTSLVITSKLLLSVAIISLVVGAFGAL 375
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 14-116 1.36e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 47.06  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  14 LLGTTITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQWDITQLTH-- 91
Cdd:COG0651   117 LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAArl 196

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2309225273  92 --------PPACLLLTTAIATKLGLAPLHFWFP 116
Cdd:COG0651   197 aeldpgllLAAFALLLVGFGIKAALFPLHFWLP 229
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-144 9.03e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 41.84  E-value: 9.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  20 TITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYF---------------LVQAAASTL-------MLFSSMIN 77
Cdd:PRK06458  124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIiicsvgvafalfgtiLVYANAATVmgdgemaILWTELLK 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  78 awHTGQWDITQLTHPPACLLLttAIATKLGLAPLHFWFPE-----------VLQGSSLTTAL---------LLSTIMKLP 137
Cdd:PRK06458  204 --HASLLDPTLMKLAFVFLLI--GFGTKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALyavlryyilIDAAIGSDF 279


                  ....*..
gi 2309225273 138 PTTLLLI 144
Cdd:PRK06458  280 PGRLLLI 286
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-134 1.20e-04

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 41.22  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  38 LSIIPM---ISKSHHPRAIEAATKYFLVQAAASTLMLFSSMINAWHTGQW--DITQLTHPP--------ACLLLTTAIAT 104
Cdd:COG1008   142 LMLIPMyflIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPlpltaqllLFLAFFIAFAV 221

                          90       100       110
                  ....*....|....*....|....*....|
gi 2309225273 105 KLGLAPLHFWFPEVLQGSSLTTALLLSTIM 134
Cdd:COG1008   222 KVPMFPFHTWLPDAHVEAPTAGSVLLAGVL 251
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-165 1.51e-03

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 38.11  E-value: 1.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  50 PRAIEAATKYFLVQAAASTLMLF-SSMINAWHTGQwdiTQLT----------HPPACLLLTTAIAT---KLGLAPLHFWF 115
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLSaialalitspSLGLALALVFVIAGiafKISAVPFHQWT 233

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2309225273 116 PEVLQGSSLTTALLLSTIMKLPPTTL---LLITSHSLNPT----LLTTMSIMSIALG 165
Cdd:PRK02504  234 PDVYEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLG 290
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-135 1.88e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 37.68  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2309225273  51 RAIEAATKYFLVQAAASTLML--FSSM--INAWHTGQWDI------TQLTHPPACLL----LTTAIATKLGLAPLHFWFP 116
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVygFSWLygLSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                          90
                  ....*....|....*....
gi 2309225273 117 EVLQGSSLTTALLLSTIMK 135
Cdd:CHL00049  239 DVYEGSPTPVVAFLSVTSK 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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