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Conserved domains on  [gi|2473904113|gb|WFD50037|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Nycticebus menagensis]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-228 2.40e-122

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00110:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 459  Bit Score: 354.97  E-value: 2.40e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINN-LNFTLMYFSDTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00110    1 MLKIIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNsLNFSLLFFSDSLSTPLLILTTWLLPLMLMAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  80 QHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00110   81 QHHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904113 160 LIIMLYTQNLAGSLNLSILPLYHRNmLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00110  161 LVALLYIQNNLGSLNFLLLQLWAQP-LPNSWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
 
Name Accession Description Interval E-value
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-228 2.40e-122

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 354.97  E-value: 2.40e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINN-LNFTLMYFSDTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00110    1 MLKIIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNsLNFSLLFFSDSLSTPLLILTTWLLPLMLMAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  80 QHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00110   81 QHHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904113 160 LIIMLYTQNLAGSLNLSILPLYHRNmLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00110  161 LVALLYIQNNLGSLNFLLLQLWAQP-LPNSWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 58-228 8.14e-32

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 120.96  E-value: 8.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKepliRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:COG1008    81 DGISLPLVLLTALLTPLAILASWNEIKK----RPKLYYALLLLLEAGMIGVFLALDLFLFYVFWELMLIPMYFLIGIWGG 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:COG1008   157 E-RRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTFDIAELAAAPL--PLTAQLLLFLAFFIAFAVKVPMFPFHTWLP 233

                         170
                  ....*....|.
gi 2473904113 218 KAHVEAPIAGS 228
Cdd:COG1008   234 DAHVEAPTAGS 244
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 58-228 8.80e-28

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 109.64  E-value: 8.80e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKepliRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:TIGR01972  76 DGISLLLVLLTALLTLLAILASWESIQK----RVKEFYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QTeRLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGsLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:TIGR01972 152 PN-RIYAAMKFFLYTLAGSLLMLLAILGLYFLGG-GTFDLLELLNLPL--PFGVQTWLFLAFFIAFAVKVPLFPLHTWLP 227

                         170
                  ....*....|.
gi 2473904113 218 KAHVEAPIAGS 228
Cdd:TIGR01972 228 DAHVEAPTAGS 238
Oxidored_q5_N pfam01059
NADH-ubiquinone oxidoreductase chain 4, amino terminus;
1-108 4.64e-23

NADH-ubiquinone oxidoreductase chain 4, amino terminus;


Pssm-ID: 366442 [Multi-domain]  Cd Length: 110  Bit Score: 89.51  E-value: 4.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNL--NFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:pfam01059   1 MLKILLPTLMLIPLTFLSKPKWLWTTSTLYSLLLALLSLLLLNNPSNFSwsNLSYFLGIDSLSYPLIILSCWLLPLMILA 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 2473904113  79 SQHHLRKEPLIRKKLYILTLITLQALLVMT 108
Cdd:pfam01059  81 SQKHLKSEPNNRQRTFIFLLILLQLFLILT 110
 
Name Accession Description Interval E-value
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-228 2.40e-122

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 354.97  E-value: 2.40e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINN-LNFTLMYFSDTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00110    1 MLKIIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNsLNFSLLFFSDSLSTPLLILTTWLLPLMLMAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  80 QHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00110   81 QHHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904113 160 LIIMLYTQNLAGSLNLSILPLYHRNmLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00110  161 LVALLYIQNNLGSLNFLLLQLWAQP-LPNSWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-228 7.40e-101

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 299.80  E-value: 7.40e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00124    1 MLKIILPTIMLIPTTLLSKPKFLWTNTTTYSLLIALLSLQWLKPPYYPTKNLTQWLGiDQISAPLLVLSCWLLPLMILAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  80 QHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00124   81 QNHLQHEPLQRKRTFLTTLILLQTFLILAFSATELTLFYIMFEATLIPTLILITRWGNQPERLSAGTYFLFYTLISSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904113 160 LIIMLYTQNLAGSLNLSILPLYHrNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00124  161 LIAILYLHNQTGTLSLPMLQLTH-PTLTNSWTNLLLWLACLMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-228 3.27e-93

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 280.65  E-value: 3.27e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00068    1 MLKIIIPTLMLLPTTWLSPKKWLWTLTTTNSLIIAFLSLMWFNLPSETMNFTNKYFGiDQISSPLLILTCWLLPLMILAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  80 QHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00068   81 QNHLKNEPINRQRTYISMLIILQLTLILAFSATELILFYIFFEATLIPTLIIITRWGNQEERLNAGTYFLFYTLAGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904113 160 LIIMLYTQNLAGSLNLSILPLYHrNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00068  161 LIALLILQNSLGSLSLILLELMS-PMQLMTYTNKIWWLACLLAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-228 3.22e-75

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 234.46  E-value: 3.22e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYF--SDTLSTPLLILTTWLLPLMILA 78
Cdd:MTH00127    1 MLKILIPTLMLIPTTWLTPAKWLWTTTLAHSLLIALASLTWLKNLSETGWSSLNLYmaTDPLSTPLLVLTCWLLPLMILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  79 SQHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLP 158
Cdd:MTH00127   81 SQNHTAPEPINRQRMYITLLTSLQIFLILAFGATEIIMFYVMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLAGSLP 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 159 LLIIMLYTQNLAGSLNLSILPlYHRNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00127  161 LLVALLLLQNSTGTLSMLTLQ-YSQPLQLSSWADKLWWAGCLLAFLVKMPLYGVHLWLPKAHVEAPIAGS 229
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 3-228 1.17e-67

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 214.80  E-value: 1.17e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   3 KIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISL--HLLHQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQ 80
Cdd:MTH00206    1 KILIPLIMLLLMTILSKKKWLWRSTTFFSFLIALLFLlwFKWSSEVGWSFSNLYLSYDPLSSPLVILSCWLLPLMFLASQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  81 HHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLL 160
Cdd:MTH00206   81 NHMKNEPINRQRIYITLLIVLQLFLILFFSSSNLLLFYILFEASLIPTLLLITRWGNQKERLNAGYYFLFYTLIGSLPLL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2473904113 161 IIMLYTQNLAGSLNLSILPLYHrnmlTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00206  161 IALLFLQNSLGSLSLYILYFSK----LTTWNNNLWWLACILAFLVKLPLYGVHLWLPKAHVEAPVAGS 224
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-228 3.77e-60

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 195.58  E-value: 3.77e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLL--HQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:MTH00044    1 MITLILLSLGIAITSWIVPKNKLWPISISQSSLISLLSLFLLnnHWSSSWHNLSLSLATDSLSSPLIILSCWLAPLSLLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  79 SQHHLRKEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLP 158
Cdd:MTH00044   81 SINHLSNNSPNNQRTFISLIIIILTALIITFSSLELILFYIAFETTLIPTLILITRWGAQKERIQAGLYFLFYTLFGSLP 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 159 LLIIMLYTQNLAGSLNLSILPLYHRNMLtPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00044  161 LLISLIAIYSSSSSLSIPLSELNWLTSL-SSNSSSIWWIFCILAFLVKMPIYGFHLWLPKAHVEAPVAGS 229
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-228 7.14e-47

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 160.32  E-value: 7.14e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLShhrTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQ 80
Cdd:MTH00163    1 MLKFLFMLLFLIPLCFLK---NSWWLVQSLLFLLSFLFMLLFSLSFYFSNISYFFGLDLLSFGLILLSFWICMLMILSSE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  81 HHLRKEPLirKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLL 160
Cdd:MTH00163   78 SVYKKNNY--SNLFLFLILFLLIFLLLTFSSMNLLLFYIFFESSLIPTLFLILGWGYQPERLQAGIYLLFYTLFASLPLL 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2473904113 161 IIMLYTQNLAGSLNLSILPLYhrnmltpSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00163  156 VGIFYLYNNSGSLSFFLLNFF-------GSLNFLWYLSMILAFLVKMPMFFVHLWLPKAHVEAPVSGS 216
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 37-228 1.10e-44

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 154.23  E-value: 1.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  37 ISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILASQHhlRKEPLIRKKLYILTLITLQALLVMTFTASELI 115
Cdd:MTH00150    1 LSLLLLYSSFSSYESLSELFSvDSMSSLLISLSLWISGLMMLASQK--SVKLRNKSSSFSLLVLLLCLILVLAFSVSSLL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 116 LFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILplyhrNMLTPSWSSD-L 194
Cdd:MTH00150   79 MFYFFFEASLIPTLLLILGWGYQPERLQAGMYMMLYTVGASLPLLLVILWMSSSYGSSFMLLI-----SSLRKLLSSMgL 153

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2473904113 195 AWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00150  154 WGLLVFLAFLVKLPMYPFHLWLPKAHVEAPVAGS 187
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 26-228 1.59e-42

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 148.97  E-value: 1.59e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  26 NVTVHSLMISSISLHLLHQPINNL--NFTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEplIRKKLYILTLITLQA 103
Cdd:MTH00205   22 SFFSNLLLIGLFFSSFFFSNSFLMtsFISSSFSFDSLSLPLIMLSFWISLLMVLASYKVFKSN--KNSKLFTVSVIMLLL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 104 LLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLsilplyhr 183
Cdd:MTH00205  100 ILILSFSVDNLLLFYITFEASLIPTLILILGWGYQPERLQASMYMMMYTLCASLPLLIGLFFLNSLNFSLSM-------- 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2473904113 184 NMLTPSWSSD----LAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00205  172 FFNFPLNFSDfylfLYWIFLMLAFLVKLPMYFVHLWLPKAHVEAPVSGS 220
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-228 6.13e-42

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 147.58  E-value: 6.13e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTlwINVTVHSLMISSISLHLLHQPIN--NLNFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:MTH00014    1 MLKLIMPLISLLLLPLIKYPWS--WALTFSTLLLLSLFTLLNLYPMSapYSMFTESLSSDMLSAPLITLTLWITALMILA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  79 SQH--HLRKEPlirkKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGS 156
Cdd:MTH00014   79 SFKifQNNKAP----KTFMTNILILNLILLLTFSASNLLMFYIFFEASLIPTLFLILGWGYQPERLQASFYLMIYTVTAS 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2473904113 157 LPLL--IIMLYTQNLAgslnlsiLPLYHRNMLTPSW-SSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00014  155 LPLLmsILLIFYTNNS-------LSMLMSSMEPPSIyLMNLWWLITILAFMVKMPLYTVHLWLPKAHVEAPVAGS 222
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 58-228 3.74e-32

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 121.85  E-value: 3.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKepliRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGn 137
Cdd:PRK05846   81 DGISLLLVVLTALLTPLAVLASWEEIKK----RVKFYMAALLWLEGGVIGVFAALDLLLFYVFFEAMLIPMYFLIGVWG- 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QTERLNAGLYFLFYTLLGSLPLL--IIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLW 215
Cdd:PRK05846  156 GKNRIYAATKFFLYTLLGSLLMLvaIIYLVVVYYNATGTFDIADLLNLPL--PPGVQYWLFLAFFIAFAVKMPMFPLHTW 233

                         170
                  ....*....|...
gi 2473904113 216 LPKAHVEAPIAGS 228
Cdd:PRK05846  234 LPDAHVQAPTAGS 246
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 58-228 8.14e-32

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 120.96  E-value: 8.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKepliRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:COG1008    81 DGISLPLVLLTALLTPLAILASWNEIKK----RPKLYYALLLLLEAGMIGVFLALDLFLFYVFWELMLIPMYFLIGIWGG 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:COG1008   157 E-RRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTFDIAELAAAPL--PLTAQLLLFLAFFIAFAVKVPMFPFHTWLP 233

                         170
                  ....*....|.
gi 2473904113 218 KAHVEAPIAGS 228
Cdd:COG1008   234 DAHVEAPTAGS 244
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 58-228 8.80e-28

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 109.64  E-value: 8.80e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKepliRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:TIGR01972  76 DGISLLLVLLTALLTLLAILASWESIQK----RVKEFYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QTeRLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGsLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:TIGR01972 152 PN-RIYAAMKFFLYTLAGSLLMLLAILGLYFLGG-GTFDLLELLNLPL--PFGVQTWLFLAFFIAFAVKVPLFPLHTWLP 227

                         170
                  ....*....|.
gi 2473904113 218 KAHVEAPIAGS 228
Cdd:TIGR01972 228 DAHVEAPTAGS 238
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 23-228 1.17e-27

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 109.38  E-value: 1.17e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  23 LWINVTVHSLMISSISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILASQHHLRkeplIRKKLYILTLITL 101
Cdd:MTH00204   46 LWGAFDGEGQFQFINLIEWIISPTLNFQWGPLVFAvDGVSLFFILLTTLLIPICILISWKSIK----FLFKEFLLCLLFL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 102 QALLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILply 181
Cdd:MTH00204  122 EVLLIGVFSVLDLLLFYILFEGILIPMFLLIGIWGSREEKVRASYYFFFYTFAGSVFMLLGIFQLYSITGTTDYQIL--- 198

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2473904113 182 hRNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00204  199 -LNIKLPLSIQKWLLVGFFLSLAVKIPQIPFHIWLPQAHVEAPVAGS 244
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 53-228 4.09e-25

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 102.31  E-value: 4.09e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  53 LMYFSDTLSTPLLILTTWLLPLMILASQHHLRkeplIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIII 132
Cdd:MTH00226   96 LVFAVDGISIYFIILTGFIVPCSILISWHSVK----YLTKSFLICMLILEFLLYAVFSVLDIFMFYILFEGVLIPMYLIL 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 133 TRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLsiLPLYHRNMLTPSWSSDLAWIACMMAFMVKMPLYGT 212
Cdd:MTH00226  172 GIWGSREEKMQAAYYFFFYTLIGSVLMLLCLFSLYNIHGTTDY--LTLASCSHVVSEQTQKWIFLGIFLAMAVKIPIFPF 249

                         170
                  ....*....|....*.
gi 2473904113 213 HLWLPKAHVEAPIAGS 228
Cdd:MTH00226  250 HIWLPKAHVEAPVAGS 265
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 58-228 8.17e-25

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 101.28  E-value: 8.17e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKepLIRKklYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:MTH00217   79 DGISIFFLILTALLTPICILISWNSIKF--LIKE--FLLCLLVIEILLMGVFTILDLVGFYILFEGILIPMFLIIGIWGS 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QTERLNAGLYFLFYTLLGSLPLL--IIMLYTQnlAGSLNLSILPLYHRNMLTPSWssdlAWIACMMAFMVKMPLYGTHLW 215
Cdd:MTH00217  155 REEKVQASYYFFFYTFIGSVFMLlgIFTLYSY--AGTTDYQALCCLKIEKELQYF----IFLGFFLSLAIKIPKIPFHIW 228

                         170
                  ....*....|...
gi 2473904113 216 LPKAHVEAPIAGS 228
Cdd:MTH00217  229 LPQAHVEAPVAGS 241
Oxidored_q5_N pfam01059
NADH-ubiquinone oxidoreductase chain 4, amino terminus;
1-108 4.64e-23

NADH-ubiquinone oxidoreductase chain 4, amino terminus;


Pssm-ID: 366442 [Multi-domain]  Cd Length: 110  Bit Score: 89.51  E-value: 4.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNL--NFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:pfam01059   1 MLKILLPTLMLIPLTFLSKPKWLWTTSTLYSLLLALLSLLLLNNPSNFSwsNLSYFLGIDSLSYPLIILSCWLLPLMILA 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 2473904113  79 SQHHLRKEPLIRKKLYILTLITLQALLVMT 108
Cdd:pfam01059  81 SQKHLKSEPNNRQRTFIFLLILLQLFLILT 110
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 111-228 7.98e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.98e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 111 ASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMLTpSW 190
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLN-SS 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2473904113 191 SSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:pfam00361  80 GLLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVS 117
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 104-228 6.67e-17

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 78.41  E-value: 6.67e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 104 LLVMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYtqnlagslNLSILPLYHr 183
Cdd:MTH00094   74 ICLLFFVSSNMLMLYMFFELSMFPILIMILGYGSQIEKINSSYYLLFYAAFFSFPFLFVYLK--------NFFFFSLCY- 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2473904113 184 NMLTPSWSSdlaWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00094  145 FDFFLSWEM---FFILSLSFMMKFPVYFLHLWLPKAHVEAPTTAS 186
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 58-223 2.68e-15

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 74.30  E-value: 2.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQHHLRKeplirKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:PRK12561   58 DGLSMPLVLLSGLITTLSIFASWKVTRK-----PRLFYFLMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGG 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNmlTPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:PRK12561  133 Q-KRLYAATKFILYTALASIFILVAGLALALSGDTFTFDLAELGAKS--YPLALELLLYAGFLIAFGVKLPIFPLHTWLP 209


                  ....*.
gi 2473904113 218 KAHVEA 223
Cdd:PRK12561  210 DAHGEA 215
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
58-223 2.94e-14

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 70.88  E-value: 2.94e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQhhlrkEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:PRK06473   78 DGLSLPLLVLNSLLTLIAIYSSD-----ESIQRPRFYYSLLLLLNAGVSGAFLAQDLLLFFLFYELELIPLYLLIAIWGG 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:PRK06473  153 Q-RRGYAATKFLLYTAISGILILVSFLGLVWLSGASSFDYEPLRSHTL--PLSTQLLLLAPILVGFGIKIPLVPFHTWLP 229


                  ....*.
gi 2473904113 218 KAHVEA 223
Cdd:PRK06473  230 DAHVEA 235
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 51-224 4.55e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 64.40  E-value: 4.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  51 FTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEPLIRKkLYILTLITLqALLVMTFTASELILFYILFEATLIPTLI 130
Cdd:COG0651    68 FGIVLVADRLSALFLLLTALVALAVLLYSIGYMRHERRGRR-FYPLFLLLL-AGMNGAFLTGDLFNLFVFFEVMLLASYG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 131 IITRWGNQtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLY 210
Cdd:COG0651   146 LVALGGTK-EALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAEL--DPGLLLAAFALLLVGFGIKAALF 222

                         170
                  ....*....|....
gi 2473904113 211 GTHLWLPKAHVEAP 224
Cdd:COG0651   223 PLHFWLPDAYPAAP 236
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 57-223 2.64e-11

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 62.42  E-value: 2.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  57 SDTLSTPLLILTTWLLPLMILASQhhlrkePLIRK-KLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRW 135
Cdd:PRK02546   85 ADGLSMPLILLTGFITTLAVLAAW------PVTFKpKLFYFLMLAMYGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIW 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 136 GNQtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLW 215
Cdd:PRK02546  159 GGK-KRQYAATKFILYTAGSSLFILLAALAMAFYGDTPTFDMTALAAKDF--GLGFQLLCYAGLLIAYGVKLPIVPLHTW 235


                  ....*...
gi 2473904113 216 LPKAHVEA 223
Cdd:PRK02546  236 LPDAHGEA 243
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
58-223 1.00e-09

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 57.80  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  58 DTLSTPLLILTTWLLPLMILASQhhlrkEPLIRKKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLIIITRWGN 137
Cdd:PRK07363   78 DGLSLPLLVLNSLLTWIAIYSIG-----ENTERPRLYYSLILLINGGIAGALLAQNLLLFFLFYELELIPFYLLIAIWGG 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 138 QtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:PRK07363  153 E-KRGYASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFDYDAISTQNL--SLNTQLILLTGLLLGFGIKIPLVPLHTWLP 229


                  ....*.
gi 2473904113 218 KAHVEA 223
Cdd:PRK07363  230 DAYTEA 235
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 106-223 2.48e-09

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 56.47  E-value: 2.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 106 VMTFTASELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSilplyhrnm 185
Cdd:MTH00062   85 ILCFCVNNSLLFWFFYELSIIPLLYLLFSESPYSERYLASWYFLGYLLLTSLPLLLCLLYLSLVNGSFNFS--------- 155

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2473904113 186 ltpSWSSDLA------WIACMMaFMVKMPLYGTHLWLPKAHVEA 223
Cdd:MTH00062  156 ---DWGSDDSvslivyYVLSFM-FITKVPLFPFHTWLPIVHAEA 195
ndhD CHL00011
NADH dehydrogenase subunit 4
 46-223 2.61e-08

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 53.41  E-value: 2.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  46 INNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQhhlrkePLIRK-KLYILTLITLQALLVMTFTASELILFYILFEAT 124
Cdd:CHL00011   71 INFFDFHWRLGIDGLSIGPILLTGFITTLATLAAW------PVTRNsRLFYFLMLAMYSGQIGLFSSRDLLLFFIMWELE 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 125 LIPTLIIITRWGNQtERLNAGLYFLFYTLLGSLPLLI----IMLYTQNLAgSLNLSILPlyhrNMLTPSWSSDLAWIACM 200
Cdd:CHL00011  145 LIPVYLLLSMWGGK-KRLYSATKFILYTAGGSIFLLIgvlgMGLYGSNEP-TLNFETLA----NQSYPVALEILFYIGFL 218

                         170       180
                  ....*....|....*....|...
gi 2473904113 201 MAFMVKMPLYGTHLWLPKAHVEA 223
Cdd:CHL00011  219 IAYAVKLPIIPLHTWLPDTHGEA 241
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-224 2.99e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 50.26  E-value: 2.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  55 YFSDTLSTPLLILTTWLLPLMILASQ----HHLRKEplirkklYILTLITLQALLVMTFTAsELILFYILFEATLIPTLI 130
Cdd:PRK08375   73 LRADSLSALFLLVTSILAIAALLYAIgygeHRQTRF-------YALFLLLLAGLLGALLTA-DLFNLFVFLEIMSLSSYA 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 131 IITRWGNQtERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPlyhrNMLTPSWSSDLAWIACMMAFMVKMPLY 210
Cdd:PRK08375  145 LVAMGGDR-RALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLA----GALAENPTVVTAFGFVLLALALKAAVF 219

                         170
                  ....*....|....
gi 2473904113 211 GTHLWLPKAHVEAP 224
Cdd:PRK08375  220 PLHTWLPRAYPAAP 233
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 51-224 2.43e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 41.50  E-value: 2.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  51 FTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEPLIrkKLYILTLITLQALLVMTFTASELILFYILFEATLIPTLI 130
Cdd:PRK12667   74 IGIVYEVDLLGALLGLLTALVMFLILIYSYWYLEHESGP--EWYYTLLLGLEAGMLGILLTGDAFNLFVMLEVLSISAYG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113 131 IITRWGNQTERLNAGLYFLFYTLLGSLPLLIIMLYTQNLAGSLNLSILPLYHRNM---------LTPSWSSDLAWIACMM 201
Cdd:PRK12667  152 LVAYYRDRGDAVEAAIKYALIGAVGTTLYFLALAFLYATFGTLNMADLSAKIRGLsfpltgglaGNPPLALGVALALALW 231

                         170       180
                  ....*....|....*....|...
gi 2473904113 202 AFMVKMPLYGTHLWLPKAHVEAP 224
Cdd:PRK12667  232 AFTIKAAIFPNHFWLPDAHPAAP 254
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 92-224 1.50e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 39.31  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113  92 KLYILTLITLQALLVMTFTAsELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLLGSLPLL--IIMLYTQnl 169
Cdd:PRK08376  122 KYYTLILLLELGMLGMAITG-DLFNFFVFLEIMSIASYALVAFRNDTWEAIEAGIKYMFVGSLASSMVLlgIALLYGQ-- 198

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2473904113 170 AGSLNLSILPlyHRNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAP 224
Cdd:PRK08376  199 YGTLNMAYLA--VKMSENPTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPAAP 251
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-150 8.37e-03

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 36.63  E-value: 8.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904113   9 IMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEPL 88
Cdd:COG1007    20 LLLLDLFLPRRSRRLLAGLALLGLLLALALLLLALGGGTGTAFGGMFVVDGFALFFKLLILLAALLVLLLSRDYLERRGL 99

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2473904113  89 IRKKLYILTLITLQALLVMTFtASELILFYILFEATLIPTLIIITRWGNQTERLNAGL-YFLF 150
Cdd:COG1007   100 LRGEFYALLLFATLGMMLMAS-ANDLLTLFLGLELLSLSLYVLVAFRRDDRRSSEAALkYFLL 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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