NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2473904119|gb|WFD50040|]
View 

NADH dehydrogenase subunit 4, partial (mitochondrion) [Nycticebus bengalensis]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-228 7.19e-124

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00110:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 459  Bit Score: 358.82  E-value: 7.19e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINN-LNFTLMYFSDTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00110    1 MLKIIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNsLNFSLLFFSDSLSTPLLILTTWLLPLMLMAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  80 QHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00110   81 QHHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904119 160 LIILLYTQNLAGSLNLSILPLYHRNmLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00110  161 LVALLYIQNNLGSLNFLLLQLWAQP-LPNSWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
 
Name Accession Description Interval E-value
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-228 7.19e-124

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 358.82  E-value: 7.19e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINN-LNFTLMYFSDTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00110    1 MLKIIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNsLNFSLLFFSDSLSTPLLILTTWLLPLMLMAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  80 QHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00110   81 QHHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904119 160 LIILLYTQNLAGSLNLSILPLYHRNmLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00110  161 LVALLYIQNNLGSLNFLLLQLWAQP-LPNSWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 58-228 5.77e-32

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 121.34  E-value: 5.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKEPlvrKKLYILMLItLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:COG1008    81 DGISLPLVLLTALLTPLAILASWNEIKKRP---KLYYALLLL-LEAGMIGVFLALDLFLFYVFWELMLIPMYFLIGIWGG 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:COG1008   157 E-RRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTFDIAELAAAPL--PLTAQLLLFLAFFIAFAVKVPMFPFHTWLP 233

                         170
                  ....*....|.
gi 2473904119 218 KAHVEAPIAGS 228
Cdd:COG1008   234 DAHVEAPTAGS 244
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 58-228 5.50e-28

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 110.03  E-value: 5.50e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKeplvRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:TIGR01972  76 DGISLLLVLLTALLTLLAILASWESIQK----RVKEFYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QTeRLNAGLYFLFYTLLGSLPLLIILLYTQNLAGsLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:TIGR01972 152 PN-RIYAAMKFFLYTLAGSLLMLLAILGLYFLGG-GTFDLLELLNLPL--PFGVQTWLFLAFFIAFAVKVPLFPLHTWLP 227

                         170
                  ....*....|.
gi 2473904119 218 KAHVEAPIAGS 228
Cdd:TIGR01972 228 DAHVEAPTAGS 238
Oxidored_q5_N pfam01059
NADH-ubiquinone oxidoreductase chain 4, amino terminus;
1-108 3.00e-23

NADH-ubiquinone oxidoreductase chain 4, amino terminus;


Pssm-ID: 366442 [Multi-domain]  Cd Length: 110  Bit Score: 89.89  E-value: 3.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNL--NFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:pfam01059   1 MLKILLPTLMLIPLTFLSKPKWLWTTSTLYSLLLALLSLLLLNNPSNFSwsNLSYFLGIDSLSYPLIILSCWLLPLMILA 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 2473904119  79 SQHHLRKEPLVRKKLYILMLITLQTLLVMT 108
Cdd:pfam01059  81 SQKHLKSEPNNRQRTFIFLLILLQLFLILT 110
 
Name Accession Description Interval E-value
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-228 7.19e-124

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 358.82  E-value: 7.19e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINN-LNFTLMYFSDTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00110    1 MLKIIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNsLNFSLLFFSDSLSTPLLILTTWLLPLMLMAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  80 QHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00110   81 QHHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904119 160 LIILLYTQNLAGSLNLSILPLYHRNmLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00110  161 LVALLYIQNNLGSLNFLLLQLWAQP-LPNSWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-228 1.00e-100

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 299.80  E-value: 1.00e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00124    1 MLKIILPTIMLIPTTLLSKPKFLWTNTTTYSLLIALLSLQWLKPPYYPTKNLTQWLGiDQISAPLLVLSCWLLPLMILAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  80 QHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00124   81 QNHLQHEPLQRKRTFLTTLILLQTFLILAFSATELTLFYIMFEATLIPTLILITRWGNQPERLSAGTYFLFYTLISSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904119 160 LIILLYTQNLAGSLNLSILPLYHrNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00124  161 LIAILYLHNQTGTLSLPMLQLTH-PTLTNSWTNLLLWLACLMAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-228 8.08e-94

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 282.19  E-value: 8.08e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILAS 79
Cdd:MTH00068    1 MLKIIIPTLMLLPTTWLSPKKWLWTLTTTNSLIIAFLSLMWFNLPSETMNFTNKYFGiDQISSPLLILTCWLLPLMILAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  80 QHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPL 159
Cdd:MTH00068   81 QNHLKNEPINRQRTYISMLIILQLTLILAFSATELILFYIFFEATLIPTLIIITRWGNQEERLNAGTYFLFYTLAGSLPL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2473904119 160 LIILLYTQNLAGSLNLSILPLYHrNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00068  161 LIALLILQNSLGSLSLILLELMS-PMQLMTYTNKIWWLACLLAFMVKMPLYGLHLWLPKAHVEAPIAGS 228
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-228 9.96e-76

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 235.62  E-value: 9.96e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYF--SDTLSTPLLILTTWLLPLMILA 78
Cdd:MTH00127    1 MLKILIPTLMLIPTTWLTPAKWLWTTTLAHSLLIALASLTWLKNLSETGWSSLNLYmaTDPLSTPLLVLTCWLLPLMILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  79 SQHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLP 158
Cdd:MTH00127   81 SQNHTAPEPINRQRMYITLLTSLQIFLILAFGATEIIMFYVMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLAGSLP 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 159 LLIILLYTQNLAGSLNLSILPlYHRNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00127  161 LLVALLLLQNSTGTLSMLTLQ-YSQPLQLSSWADKLWWAGCLLAFLVKMPLYGVHLWLPKAHVEAPIAGS 229
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 3-228 7.76e-68

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 215.19  E-value: 7.76e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   3 KIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISL--HLLHQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQ 80
Cdd:MTH00206    1 KILIPLIMLLLMTILSKKKWLWRSTTFFSFLIALLFLlwFKWSSEVGWSFSNLYLSYDPLSSPLVILSCWLLPLMFLASQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  81 HHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLL 160
Cdd:MTH00206   81 NHMKNEPINRQRIYITLLIVLQLFLILFFSSSNLLLFYILFEASLIPTLLLITRWGNQKERLNAGYYFLFYTLIGSLPLL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2473904119 161 IILLYTQNLAGSLNLSILPLYHrnmlTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00206  161 IALLFLQNSLGSLSLYILYFSK----LTTWNNNLWWLACILAFLVKLPLYGVHLWLPKAHVEAPVAGS 224
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-228 8.24e-62

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 199.82  E-value: 8.24e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLL--HQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:MTH00044    1 MITLILLSLGIAITSWIVPKNKLWPISISQSSLISLLSLFLLnnHWSSSWHNLSLSLATDSLSSPLIILSCWLAPLSLLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  79 SQHHLRKEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLP 158
Cdd:MTH00044   81 SINHLSNNSPNNQRTFISLIIIILTALIITFSSLELILFYIAFETTLIPTLILITRWGAQKERIQAGLYFLFYTLFGSLP 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 159 LLIILLYTQNLAGSLNLSILPLYHRNMLtPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00044  161 LLISLIAIYSSSSSLSIPLSELNWLTSL-SSNSSSIWWIFCILAFLVKMPIYGFHLWLPKAHVEAPVAGS 229
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-228 5.43e-47

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 160.70  E-value: 5.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLShhrTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQ 80
Cdd:MTH00163    1 MLKFLFMLLFLIPLCFLK---NSWWLVQSLLFLLSFLFMLLFSLSFYFSNISYFFGLDLLSFGLILLSFWICMLMILSSE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  81 HHLRKepLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLL 160
Cdd:MTH00163   78 SVYKK--NNYSNLFLFLILFLLIFLLLTFSSMNLLLFYIFFESSLIPTLFLILGWGYQPERLQAGIYLLFYTLFASLPLL 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2473904119 161 IILLYTQNLAGSLNLSILPLYhrnmltpSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00163  156 VGIFYLYNNSGSLSFFLLNFF-------GSLNFLWYLSMILAFLVKMPMFFVHLWLPKAHVEAPVSGS 216
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 37-228 4.63e-45

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 155.00  E-value: 4.63e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  37 ISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILASQHhlRKEPLVRKKLYILMLITLQTLLVMTFTASELI 115
Cdd:MTH00150    1 LSLLLLYSSFSSYESLSELFSvDSMSSLLISLSLWISGLMMLASQK--SVKLRNKSSSFSLLVLLLCLILVLAFSVSSLL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 116 LFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILplyhrNMLTPSWSSD-L 194
Cdd:MTH00150   79 MFYFFFEASLIPTLLLILGWGYQPERLQAGMYMMLYTVGASLPLLLVILWMSSSYGSSFMLLI-----SSLRKLLSSMgL 153

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2473904119 195 AWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00150  154 WGLLVFLAFLVKLPMYPFHLWLPKAHVEAPVAGS 187
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 26-228 1.59e-42

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 148.97  E-value: 1.59e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  26 NVTVHSLMISSISLHLLHQPINNL--NFTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEplVRKKLYILMLITLQT 103
Cdd:MTH00205   22 SFFSNLLLIGLFFSSFFFSNSFLMtsFISSSFSFDSLSLPLIMLSFWISLLMVLASYKVFKSN--KNSKLFTVSVIMLLL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 104 LLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLsilplyhr 183
Cdd:MTH00205  100 ILILSFSVDNLLLFYITFEASLIPTLILILGWGYQPERLQASMYMMMYTLCASLPLLIGLFFLNSLNFSLSM-------- 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2473904119 184 NMLTPSWSSD----LAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00205  172 FFNFPLNFSDfylfLYWIFLMLAFLVKLPMYFVHLWLPKAHVEAPVSGS 220
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-228 2.80e-42

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 148.35  E-value: 2.80e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTlwINVTVHSLMISSISLHLLHQPIN--NLNFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:MTH00014    1 MLKLIMPLISLLLLPLIKYPWS--WALTFSTLLLLSLFTLLNLYPMSapYSMFTESLSSDMLSAPLITLTLWITALMILA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  79 SQH--HLRKEPlvrkKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGS 156
Cdd:MTH00014   79 SFKifQNNKAP----KTFMTNILILNLILLLTFSASNLLMFYIFFEASLIPTLFLILGWGYQPERLQASFYLMIYTVTAS 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2473904119 157 LPLL--IILLYTQNLAgslnlsiLPLYHRNMLTPSW-SSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00014  155 LPLLmsILLIFYTNNS-------LSMLMSSMEPPSIyLMNLWWLITILAFMVKMPLYTVHLWLPKAHVEAPVAGS 222
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 58-228 5.77e-32

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 121.34  E-value: 5.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKEPlvrKKLYILMLItLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:COG1008    81 DGISLPLVLLTALLTPLAILASWNEIKKRP---KLYYALLLL-LEAGMIGVFLALDLFLFYVFWELMLIPMYFLIGIWGG 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:COG1008   157 E-RRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTFDIAELAAAPL--PLTAQLLLFLAFFIAFAVKVPMFPFHTWLP 233

                         170
                  ....*....|.
gi 2473904119 218 KAHVEAPIAGS 228
Cdd:COG1008   234 DAHVEAPTAGS 244
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 58-228 9.94e-32

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 120.69  E-value: 9.94e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKeplvRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGn 137
Cdd:PRK05846   81 DGISLLLVVLTALLTPLAVLASWEEIKK----RVKFYMAALLWLEGGVIGVFAALDLLLFYVFFEAMLIPMYFLIGVWG- 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QTERLNAGLYFLFYTLLGSLPLL--IILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLW 215
Cdd:PRK05846  156 GKNRIYAATKFFLYTLLGSLLMLvaIIYLVVVYYNATGTFDIADLLNLPL--PPGVQYWLFLAFFIAFAVKMPMFPLHTW 233

                         170
                  ....*....|...
gi 2473904119 216 LPKAHVEAPIAGS 228
Cdd:PRK05846  234 LPDAHVQAPTAGS 246
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 58-228 5.50e-28

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 110.03  E-value: 5.50e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKeplvRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:TIGR01972  76 DGISLLLVLLTALLTLLAILASWESIQK----RVKEFYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QTeRLNAGLYFLFYTLLGSLPLLIILLYTQNLAGsLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:TIGR01972 152 PN-RIYAAMKFFLYTLAGSLLMLLAILGLYFLGG-GTFDLLELLNLPL--PFGVQTWLFLAFFIAFAVKVPLFPLHTWLP 227

                         170
                  ....*....|.
gi 2473904119 218 KAHVEAPIAGS 228
Cdd:TIGR01972 228 DAHVEAPTAGS 238
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 23-228 2.67e-27

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 108.23  E-value: 2.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  23 LWINVTVHSLMISSISLHLLHQPINNLNFTLMYFS-DTLSTPLLILTTWLLPLMILASQHHLRkeplVRKKLYILMLITL 101
Cdd:MTH00204   46 LWGAFDGEGQFQFINLIEWIISPTLNFQWGPLVFAvDGVSLFFILLTTLLIPICILISWKSIK----FLFKEFLLCLLFL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 102 QTLLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILply 181
Cdd:MTH00204  122 EVLLIGVFSVLDLLLFYILFEGILIPMFLLIGIWGSREEKVRASYYFFFYTFAGSVFMLLGIFQLYSITGTTDYQIL--- 198

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2473904119 182 hRNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00204  199 -LNIKLPLSIQKWLLVGFFLSLAVKIPQIPFHIWLPQAHVEAPVAGS 244
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 53-228 1.67e-25

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 103.46  E-value: 1.67e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  53 LMYFSDTLSTPLLILTTWLLPLMILASQHHLRkepLVRKKLYILMLItLQTLLVMTFTASELILFYILFEATLIPTLVII 132
Cdd:MTH00226   96 LVFAVDGISIYFIILTGFIVPCSILISWHSVK---YLTKSFLICMLI-LEFLLYAVFSVLDIFMFYILFEGVLIPMYLIL 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 133 TRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLsiLPLYHRNMLTPSWSSDLAWIACMMAFMVKMPLYGT 212
Cdd:MTH00226  172 GIWGSREEKMQAAYYFFFYTLIGSVLMLLCLFSLYNIHGTTDY--LTLASCSHVVSEQTQKWIFLGIFLAMAVKIPIFPF 249

                         170
                  ....*....|....*.
gi 2473904119 213 HLWLPKAHVEAPIAGS 228
Cdd:MTH00226  250 HIWLPKAHVEAPVAGS 265
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 58-228 5.96e-24

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 98.97  E-value: 5.96e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKepLVRKklYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:MTH00217   79 DGISIFFLILTALLTPICILISWNSIKF--LIKE--FLLCLLVIEILLMGVFTILDLVGFYILFEGILIPMFLIIGIWGS 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QTERLNAGLYFLFYTLLGSLPLL--IILLYTQnlAGSLNLSILPLYHRNMLTPSWssdlAWIACMMAFMVKMPLYGTHLW 215
Cdd:MTH00217  155 REEKVQASYYFFFYTFIGSVFMLlgIFTLYSY--AGTTDYQALCCLKIEKELQYF----IFLGFFLSLAIKIPKIPFHIW 228

                         170
                  ....*....|...
gi 2473904119 216 LPKAHVEAPIAGS 228
Cdd:MTH00217  229 LPQAHVEAPVAGS 241
Oxidored_q5_N pfam01059
NADH-ubiquinone oxidoreductase chain 4, amino terminus;
1-108 3.00e-23

NADH-ubiquinone oxidoreductase chain 4, amino terminus;


Pssm-ID: 366442 [Multi-domain]  Cd Length: 110  Bit Score: 89.89  E-value: 3.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   1 MLKIIIPTIMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNL--NFTLMYFSDTLSTPLLILTTWLLPLMILA 78
Cdd:pfam01059   1 MLKILLPTLMLIPLTFLSKPKWLWTTSTLYSLLLALLSLLLLNNPSNFSwsNLSYFLGIDSLSYPLIILSCWLLPLMILA 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 2473904119  79 SQHHLRKEPLVRKKLYILMLITLQTLLVMT 108
Cdd:pfam01059  81 SQKHLKSEPNNRQRTFIFLLILLQLFLILT 110
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 111-228 1.91e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 89.68  E-value: 1.91e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 111 ASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMLTpSW 190
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLN-SS 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2473904119 191 SSDLAWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:pfam00361  80 GLLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVS 117
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 104-228 1.51e-16

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 77.64  E-value: 1.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 104 LLVMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYtqnlagslNLSILPLYHr 183
Cdd:MTH00094   74 ICLLFFVSSNMLMLYMFFELSMFPILIMILGYGSQIEKINSSYYLLFYAAFFSFPFLFVYLK--------NFFFFSLCY- 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2473904119 184 NMLTPSWSSdlaWIACMMAFMVKMPLYGTHLWLPKAHVEAPIAGS 228
Cdd:MTH00094  145 FDFFLSWEM---FFILSLSFMMKFPVYFLHLWLPKAHVEAPTTAS 186
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 58-223 3.27e-15

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 73.91  E-value: 3.27e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKeplvrKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:PRK12561   58 DGLSMPLVLLSGLITTLSIFASWKVTRK-----PRLFYFLMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGG 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNmlTPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:PRK12561  133 Q-KRLYAATKFILYTALASIFILVAGLALALSGDTFTFDLAELGAKS--YPLALELLLYAGFLIAFGVKLPIFPLHTWLP 209


                  ....*.
gi 2473904119 218 KAHVEA 223
Cdd:PRK12561  210 DAHGEA 215
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
58-223 2.23e-14

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 71.27  E-value: 2.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQhhlrkEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:PRK06473   78 DGLSLPLLVLNSLLTLIAIYSSD-----ESIQRPRFYYSLLLLLNAGVSGAFLAQDLLLFFLFYELELIPLYLLIAIWGG 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:PRK06473  153 Q-RRGYAATKFLLYTAISGILILVSFLGLVWLSGASSFDYEPLRSHTL--PLSTQLLLLAPILVGFGIKIPLVPFHTWLP 229


                  ....*.
gi 2473904119 218 KAHVEA 223
Cdd:PRK06473  230 DAHVEA 235
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 51-224 1.52e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 65.94  E-value: 1.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  51 FTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEPLVRKkLYILMLITLQTLLvMTFTASELILFYILFEATLIPTLV 130
Cdd:COG0651    68 FGIVLVADRLSALFLLLTALVALAVLLYSIGYMRHERRGRR-FYPLFLLLLAGMN-GAFLTGDLFNLFVFFEVMLLASYG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 131 IITRWGNQtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLY 210
Cdd:COG0651   146 LVALGGTK-EALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAEL--DPGLLLAAFALLLVGFGIKAALF 222

                         170
                  ....*....|....
gi 2473904119 211 GTHLWLPKAHVEAP 224
Cdd:COG0651   223 PLHFWLPDAYPAAP 236
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 57-223 2.54e-11

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 62.42  E-value: 2.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  57 SDTLSTPLLILTTWLLPLMILASQhhlrkePLVRK-KLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRW 135
Cdd:PRK02546   85 ADGLSMPLILLTGFITTLAVLAAW------PVTFKpKLFYFLMLAMYGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIW 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 136 GNQtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLW 215
Cdd:PRK02546  159 GGK-KRQYAATKFILYTAGSSLFILLAALAMAFYGDTPTFDMTALAAKDF--GLGFQLLCYAGLLIAYGVKLPIVPLHTW 235


                  ....*...
gi 2473904119 216 LPKAHVEA 223
Cdd:PRK02546  236 LPDAHGEA 243
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
58-223 4.70e-10

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 58.57  E-value: 4.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQhhlrkEPLVRKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLVIITRWGN 137
Cdd:PRK07363   78 DGLSLPLLVLNSLLTWIAIYSIG-----ENTERPRLYYSLILLINGGIAGALLAQNLLLFFLFYELELIPFYLLIAIWGG 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNMltPSWSSDLAWIACMMAFMVKMPLYGTHLWLP 217
Cdd:PRK07363  153 E-KRGYASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFDYDAISTQNL--SLNTQLILLTGLLLGFGIKIPLVPLHTWLP 229


                  ....*.
gi 2473904119 218 KAHVEA 223
Cdd:PRK07363  230 DAYTEA 235
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 106-223 6.51e-10

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 58.01  E-value: 6.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 106 VMTFTASELILFYILFEATLIPTLVIITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSilplyhrnm 185
Cdd:MTH00062   85 ILCFCVNNSLLFWFFYELSIIPLLYLLFSESPYSERYLASWYFLGYLLLTSLPLLLCLLYLSLVNGSFNFS--------- 155

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2473904119 186 ltpSWSSDLA------WIACMMaFMVKMPLYGTHLWLPKAHVEA 223
Cdd:MTH00062  156 ---DWGSDDSvslivyYVLSFM-FITKVPLFPFHTWLPIVHAEA 195
ndhD CHL00011
NADH dehydrogenase subunit 4
 46-223 3.84e-09

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 56.11  E-value: 3.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  46 INNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQhhlrkePLVR--KKLYILMLItLQTLLVMTFTASELILFYILFEA 123
Cdd:CHL00011   71 INFFDFHWRLGIDGLSIGPILLTGFITTLATLAAW------PVTRnsRLFYFLMLA-MYSGQIGLFSSRDLLLFFIMWEL 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 124 TLIPTLVIITRWGNQtERLNAGLYFLFYTLLGSLPLLIILLyTQNLAGS----LNLSILPlyhrNMLTPSWSSDLAWIAC 199
Cdd:CHL00011  144 ELIPVYLLLSMWGGK-KRLYSATKFILYTAGGSIFLLIGVL-GMGLYGSneptLNFETLA----NQSYPVALEILFYIGF 217

                         170       180
                  ....*....|....*....|....
gi 2473904119 200 MMAFMVKMPLYGTHLWLPKAHVEA 223
Cdd:CHL00011  218 LIAYAVKLPIIPLHTWLPDTHGEA 241
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-224 1.17e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 48.34  E-value: 1.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  55 YFSDTLSTPLLILTTWLLPLMILASQ----HHLRKEplvrkklYILMLITLQTLLVMTFTAsELILFYILFEATLIPTLV 130
Cdd:PRK08375   73 LRADSLSALFLLVTSILAIAALLYAIgygeHRQTRF-------YALFLLLLAGLLGALLTA-DLFNLFVFLEIMSLSSYA 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 131 IITRWGNQtERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPlyhrNMLTPSWSSDLAWIACMMAFMVKMPLY 210
Cdd:PRK08375  145 LVAMGGDR-RALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLA----GALAENPTVVTAFGFVLLALALKAAVF 219

                         170
                  ....*....|....
gi 2473904119 211 GTHLWLPKAHVEAP 224
Cdd:PRK08375  220 PLHTWLPRAYPAAP 233
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 51-224 1.55e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 42.27  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  51 FTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEPLvrKKLYILMLITLQTLLVMTFTASELILFYILFEATLIPTLV 130
Cdd:PRK12667   74 IGIVYEVDLLGALLGLLTALVMFLILIYSYWYLEHESG--PEWYYTLLLGLEAGMLGILLTGDAFNLFVMLEVLSISAYG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 131 IITRWGNQTERLNAGLYFLFYTLLGSLPLLIILLYTQNLAGSLNLSILPLYHRNM---------LTPSWSSDLAWIACMM 201
Cdd:PRK12667  152 LVAYYRDRGDAVEAAIKYALIGAVGTTLYFLALAFLYATFGTLNMADLSAKIRGLsfpltgglaGNPPLALGVALALALW 231

                         170       180
                  ....*....|....*....|...
gi 2473904119 202 AFMVKMPLYGTHLWLPKAHVEAP 224
Cdd:PRK12667  232 AFTIKAAIFPNHFWLPDAHPAAP 254
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 58-224 8.55e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 40.08  E-value: 8.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  58 DTLSTPLLILTTWLLPLMILASQHHLRKEPLVRKKLYILMLITLQTLLVMTftASELILFYILFEATLIPTLVIITRWGN 137
Cdd:PRK08376   89 DLFGAFMALIATIVSFLAVLYSISYMKHDTGLDKYYTLILLLELGMLGMAI--TGDLFNFFVFLEIMSIASYALVAFRND 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119 138 QTERLNAGLYFLFYTLLGSLPLL--IILLYTQnlAGSLNLSILPlyHRNMLTPSWSSDLAWIACMMAFMVKMPLYGTHLW 215
Cdd:PRK08376  167 TWEAIEAGIKYMFVGSLASSMVLlgIALLYGQ--YGTLNMAYLA--VKMSENPTVVAKIALALFIAGLAMKSGAVPVHMW 242


                  ....*....
gi 2473904119 216 LPKAHVEAP 224
Cdd:PRK08376  243 LPDAYPAAP 251
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-176 6.99e-03

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 37.02  E-value: 6.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119   9 IMLVPVTWLSHHRTLWINVTVHSLMISSISLHLLHQPINNLNFTLMYFSDTLSTPLLILTTWLLPLMILASQHHLRKEPL 88
Cdd:COG1007    20 LLLLDLFLPRRSRRLLAGLALLGLLLALALLLLALGGGTGTAFGGMFVVDGFALFFKLLILLAALLVLLLSRDYLERRGL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2473904119  89 VRKKLYILMLITLQTLLVMTFtASELILFYILFEATLIPTLVIITRWGNQTERLNAGL-YFLFYTLLGSLPLL-IILLYT 166
Cdd:COG1007   100 LRGEFYALLLFATLGMMLMAS-ANDLLTLFLGLELLSLSLYVLVAFRRDDRRSSEAALkYFLLGALSSGFLLYgISLLYG 178

                         170
                  ....*....|
gi 2473904119 167 qnLAGSLNLS 176
Cdd:COG1007   179 --ATGSLNLA 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH