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Conserved domains on  [gi|2504469450|gb|WHE45012|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Brachaspis nivalis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-218 9.28e-60

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 190.42  E-value: 9.28e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   1 GVWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNNSMeweSEIIPSMMISSSLLLKIGAAP 80
Cdd:MTH00160   29 GAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLML---FNNISSMLINSSLLLKLGAAP 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  81 FHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQlSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMIS 160
Cdd:MTH00160  106 FHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLS 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2504469450 161 SLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00160  185 SMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLS 242
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-218 9.28e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 190.42  E-value: 9.28e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   1 GVWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNNSMeweSEIIPSMMISSSLLLKIGAAP 80
Cdd:MTH00160   29 GAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLML---FNNISSMLINSSLLLKLGAAP 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  81 FHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQlSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMIS 160
Cdd:MTH00160  106 FHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLS 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2504469450 161 SLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00160  185 SMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLS 242
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 3-176 2.98e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 86.21  E-value: 2.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   3 WMGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLFSILLI--------------QMNNSMEWESEIIPSMM 67
Cdd:pfam00361   8 YLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSGLLLLFLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  68 ISSSLLLKIGAAPFHFWFPEVMGASSWINCLTL-MTWQKIAPMMVL-------SYCIQLSTFMFFITIMSVFIGAMGGLN 139
Cdd:pfam00361  88 ILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLLGSLAALV 167

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2504469450 140 QTSLRQLLAYSSISHIGWMISSLIIGENIWELYFIIY 176
Cdd:pfam00361 168 QTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFH 204
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-165 1.76e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 74.38  E-value: 1.76e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   4 MGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLF----------SILLIQMNNSMEWESEIIPSMMISSSL 72
Cdd:COG1007   129 LGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLNLAGIAAALAAGGANSPLLLLGLVL 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  73 LL-----KIGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVL---------SYCIQLSTFMFFITIMSVFIGAMGGL 138
Cdd:COG1007   209 VLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGLAADWQLLLAVLAVLSMTVGNLAAL 288

                         170       180
                  ....*....|....*....|....*..
gi 2504469450 139 NQTSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:COG1007   289 AQTNVKRMLAYSSIAHAGYLLLGLAAG 315
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-165 1.19e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 66.12  E-value: 1.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   1 GVWMGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLFSI--------------LLIQMNNSMEWESEIIPS 65
Cdd:TIGR01770 126 SIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGIsliygftgslnfedLLLFLSNGMLNISLLLLG 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  66 M-MISSSLLLKIGAAPFHFWFPEVMGASSWINCLTLMTWQKIA---PMMVLSYCIQ------LSTFMFFITIMSVFIGAM 135
Cdd:TIGR01770 206 IvLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLAIIAFLSMLIGNF 285

                         170       180       190
                  ....*....|....*....|....*....|
gi 2504469450 136 GGLNQTSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:TIGR01770 286 GALAQKKVKRLLAYSSISHVGYILIGLLAG 315
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-218 9.28e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 190.42  E-value: 9.28e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   1 GVWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNNSMeweSEIIPSMMISSSLLLKIGAAP 80
Cdd:MTH00160   29 GAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLML---FNNISSMLINSSLLLKLGAAP 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  81 FHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQlSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMIS 160
Cdd:MTH00160  106 FHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLS 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2504469450 161 SLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00160  185 SMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLS 242
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 3-176 2.87e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 148.43  E-value: 2.87e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   3 WMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNNSmEWE----SEIIPSMMISSSLLLKIGA 78
Cdd:MTH00112   30 WTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTG-QWDitqlTNPTSCTLLTLALAMKLGL 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  79 APFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQL--STFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIG 156
Cdd:MTH00112  109 APFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlnPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSIAHLG 188

                         170       180
                  ....*....|....*....|
gi 2504469450 157 WMISSLIIGENIWELYFIIY 176
Cdd:MTH00112  189 WMIAIITYSPKLTLLTFYIY 208
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 2-218 2.97e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 143.15  E-value: 2.97e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILlIQMNNSMEW----ESEIIPSMMISSSLLLKIG 77
Cdd:MTH00041   29 IWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWLSGSWsingPLNTLSSIIITLALALKLG 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  78 AAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQLSTFMFFIT--IMSVFIGAMGGLNQTSLRQLLAYSSISHI 155
Cdd:MTH00041  108 LAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILcgILSVLVGGWGGLNQTQTRKILAFSSIAHL 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2504469450 156 GWMISSLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00041  188 GWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILS 250
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 2-218 3.32e-41

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 143.06  E-value: 3.32e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNN---SMEWESEIIPSMMISSSLLLKIGA 78
Cdd:MTH00105   29 AWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSgqwTITKLTNPTASTLMTIALAMKLGL 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  79 APFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLsYCIQLS---TFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHI 155
Cdd:MTH00105  109 APFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIL-YQISPSinpNLLLTLAILSILIGGWGGLNQTQLRKILAYSSIAHM 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2504469450 156 GWMISSLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00105  188 GWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLS 250
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 2-218 5.84e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 139.67  E-value: 5.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILliqMNNSMEWESEII------PSMMISSSLLLK 75
Cdd:MTH00070   29 AWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSST---INAWFTGEWTIMnmqtplPTIMLTIALMMK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  76 IGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLsycIQLS-----TFMFFITIMSVFIGAMGGLNQTSLRQLLAYS 150
Cdd:MTH00070  106 LGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALL---IQIShllnsNLLIIMGLLSTLIGGWGGLNQTQLRKIMAYS 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2504469450 151 SISHIGWMISSLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIySASNMKTEIKF-MMFLSLLS 218
Cdd:MTH00070  183 SIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKL-SSSWSKNPTLTsMMMLTLLS 250
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 3-159 2.33e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 138.01  E-value: 2.33e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   3 WMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSilliQMNN---SMEWE----SEIIPSMMISSSLLLK 75
Cdd:MTH00135   30 WMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFA----STTNawlTGQWDiqqmSHPLPTTMITLALALK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  76 IGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLsycIQL----STFMFFITIMSVFIGAMGGLNQTSLRQLLAYSS 151
Cdd:MTH00135  106 IGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALI---LQIaptnPTLLITLGLTSTLVGGWGGLNQTQLRKILAYSS 182


                  ....*...
gi 2504469450 152 ISHIGWMI 159
Cdd:MTH00135  183 IAHLGWMI 190
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 2-218 5.95e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 136.34  E-value: 5.95e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNNSMEWESeiipSMMISSSLLLKIGAAPF 81
Cdd:MTH00197   23 VWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLS----VVLVILGLLLKLGAFPF 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  82 HFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMISS 161
Cdd:MTH00197   99 HFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSNIRQLLAYSSIGHTGWMLMS 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2504469450 162 LIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00197  179 LVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLS 235
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-216 2.32e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 135.01  E-value: 2.32e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   1 GVWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILlIQMNNSMEWESeiipSMMISSSLLLKIGAAP 80
Cdd:MTH00144   28 GVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSL-IMYNLSFSWFS----MSLLLLGLCLKLGLFP 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  81 FHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCI---QLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGW 157
Cdd:MTH00144  103 FHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLdlyWLAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGW 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2504469450 158 MISSLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSL 216
Cdd:MTH00144  183 MLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLL 241
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 2-218 2.56e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 135.48  E-value: 2.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSiLLIQMNNSMEWE----SEIIPSMMISSSLLLKIG 77
Cdd:MTH00200   29 IWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFG-GLLNAWTSGQWGisemLGPLSETLILLALALKLG 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  78 AAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLS--YCIQLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHI 155
Cdd:MTH00200  108 LAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILAYSSIAHL 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2504469450 156 GWMISSLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00200  188 GWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLS 250
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 2-218 2.30e-36

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 129.90  E-value: 2.30e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNNSMeweSEIIPSMMISSSLLLKIGAAPF 81
Cdd:MTH00011   31 LWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSL---LKNITALMLLVSLMLKLGMAPC 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  82 HFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYC--IQLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMI 159
Cdd:MTH00011  108 HFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMT 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2504469450 160 SSLIIGENIWELYFIIYSLLSLILVLLFKQENLFFMNQIYSASNMKTEIKFMMFLSLLS 218
Cdd:MTH00011  188 MISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLS 246
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 3-176 2.98e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 86.21  E-value: 2.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   3 WMGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLFSILLI--------------QMNNSMEWESEIIPSMM 67
Cdd:pfam00361   8 YLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSGLLLLFLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  68 ISSSLLLKIGAAPFHFWFPEVMGASSWINCLTL-MTWQKIAPMMVL-------SYCIQLSTFMFFITIMSVFIGAMGGLN 139
Cdd:pfam00361  88 ILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLLGSLAALV 167

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2504469450 140 QTSLRQLLAYSSISHIGWMISSLIIGENIWELYFIIY 176
Cdd:pfam00361 168 QTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFH 204
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 2-176 3.95e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 81.99  E-value: 3.95e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTM-TNESSIKYFIVQAMASTMLLFSILL---------IQMNNSMEWESeiIPSMMISSS 71
Cdd:MTH00199  122 IYLAIELQTLTLFILVALKRDSAySTEAGLKYFVLGAVSSGLFLFGCALlygltgetsIQGINSILTGD--VGKILITIS 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  72 LLLKIGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSS 151
Cdd:MTH00199  200 LLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIGALNQTKIKRLLAYSG 279

                         170       180
                  ....*....|....*....|....*....
gi 2504469450 152 ISHIGWMISSLIIGEN----IWELYFIIY 176
Cdd:MTH00199  280 IGHMGFILFGVAIGSFesiqASLIYMIIY 308
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-165 3.95e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 79.09  E-value: 3.95e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   4 MGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLFSILLI--------------QMNNSMEWESEIIPSM-M 67
Cdd:PRK05777  130 LGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLygatgslsfagiakALADGSGNSLLLLFGLvF 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  68 ISSSLLLKIGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVL---------SYCIQLSTFMFFITIMSVFIGAMGGL 138
Cdd:PRK05777  210 LLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGLSEDWQQVLAIIAIASMLVGNLAAL 289

                         170       180
                  ....*....|....*....|....*..
gi 2504469450 139 NQTSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:PRK05777  290 SQTNIKRLLAYSSIAHAGYLLVGLAAG 316
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 2-165 4.01e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 78.53  E-value: 4.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   2 VWMGLEINLLSFIPLLANNKNTMTN-ESSIKYFIVQAMASTMLLFSILLI--------------QMNNSMEWESEIIP-- 64
Cdd:MTH00196   18 VYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFGCALLcgttgglhlsyinlVLNSGQSFSSVSVPig 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  65 SMMISSSLLLKIGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLSYCIQLSTFMFFITIMSVFIGAMGGLNQTSLR 144
Cdd:MTH00196   98 YLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSLFVGAIGALNQTKIK 177

                         170       180
                  ....*....|....*....|.
gi 2504469450 145 QLLAYSSISHIGWMISSLIIG 165
Cdd:MTH00196  178 RLLAYSGIGHMGFVLWGIEIG 198
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-165 1.76e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 74.38  E-value: 1.76e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   4 MGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLF----------SILLIQMNNSMEWESEIIPSMMISSSL 72
Cdd:COG1007   129 LGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLNLAGIAAALAAGGANSPLLLLGLVL 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  73 LL-----KIGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVL---------SYCIQLSTFMFFITIMSVFIGAMGGL 138
Cdd:COG1007   209 VLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGLAADWQLLLAVLAVLSMTVGNLAAL 288

                         170       180
                  ....*....|....*....|....*..
gi 2504469450 139 NQTSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:COG1007   289 AQTNVKRMLAYSSIAHAGYLLLGLAAG 315
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-165 1.19e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 66.12  E-value: 1.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   1 GVWMGLEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLFSI--------------LLIQMNNSMEWESEIIPS 65
Cdd:TIGR01770 126 SIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGIsliygftgslnfedLLLFLSNGMLNISLLLLG 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  66 M-MISSSLLLKIGAAPFHFWFPEVMGASSWINCLTLMTWQKIA---PMMVLSYCIQ------LSTFMFFITIMSVFIGAM 135
Cdd:TIGR01770 206 IvLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLAIIAFLSMLIGNF 285

                         170       180       190
                  ....*....|....*....|....*....|
gi 2504469450 136 GGLNQTSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:TIGR01770 286 GALAQKKVKRLLAYSSISHVGYILIGLLAG 315
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 27-159 4.58e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.49  E-value: 4.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  27 ESSIKYFIVQAMASTMLLF----------------SILLIQMNNS-MEWESEIIPSMMISSSLLLKIGAAPFHFWFPEVM 89
Cdd:MTH00198  247 ESGLKYWILGAMSSGFYLFgcalyfgftgnegmlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVY 326

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  90 GASSWINCLTLMTWQKIAPMMVLSYCIQLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMI 159
Cdd:MTH00198  327 EGAPTPTTALIAIIPKFTVYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-165 3.19e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 55.87  E-value: 3.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   6 LEINLLSFIPLLA-NNKNTMTNESSIKYFIVQAMASTMLLFSILL--------------IQMNNSMEWESEIIPSMMISS 70
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGIALlygqygtlnmaylaVKMSENPTVVAKIALALFIAG 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  71 sLLLKIGAAPFHFWFPEVMGAS-SWINCLTLMTWQ-KIAPMMVLSYCIQLSTF--------MFFITIMSVFIGAMGGLNQ 140
Cdd:PRK08376  230 -LAMKSGAVPVHMWLPDAYPAApSSISAMLLVIKQaGLYALARVLFSIYGPAInlatvgwvIIILGCLTMFVGVAMAVVQ 308

                         170       180
                  ....*....|....*....|....*
gi 2504469450 141 TSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:PRK08376  309 KDVKRLLAYHSVSQIGYMLLGLGVG 333
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 3-159 7.81e-09

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 54.77  E-value: 7.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   3 WMGLEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLI-QMNNSMEWE------SEIIPSMMISSSLLL- 74
Cdd:COG0651   133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLyGATGTLNMAdlaarlAELDPGLLLAAFALLl 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  75 -----KIGAAPFHFWFPEVMG-ASSWINCL--TLMTwqKIAPMMVL---------SYCIQLSTFMFFITIMSVFIGAMGG 137
Cdd:COG0651   213 vgfgiKAALFPLHFWLPDAYPaAPSPVSALlsGLLT--KVGVYAILrvltllfgaDPALFLGTLLLVLGLLTMLVGALGA 290

                         170       180
                  ....*....|....*....|..
gi 2504469450 138 LNQTSLRQLLAYSSISHIGWMI 159
Cdd:COG0651   291 LAQRDLKRLLAYSSVSQIGYIL 312
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-159 3.33e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 49.88  E-value: 3.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   6 LEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLIQMNN---SMEWESEIIPSM--------MISSSLLL 74
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTgtlNMADLAGALAENptvvtafgFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  75 KIGAAPFHFWFPEVM-GASSWINCLTLMTWQKIAPMMVLSYCIQLSTFMFF-----------ITIMSVFIGAMGGLNQTS 142
Cdd:PRK08375  215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYALIRIYFTVFGGDFRfalglgwllavLALLSMLVGSLAALGQDD 294

                         170
                  ....*....|....*..
gi 2504469450 143 LRQLLAYSSISHIGWMI 159
Cdd:PRK08375  295 VKRVLAYSTVSQMGYIL 311
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
25-165 3.32e-06

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 46.97  E-value: 3.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  25 TNESSIKYFIVQAMASTMLLFSI-LLIQMNNSMEWESEIIPSMMISSSLLL-------------KIGAAPFHFWFPEVMG 90
Cdd:PRK02504  159 SNEAALKYLLIGAASSAIFLYGSsLLYGLSGGSTQLSAIALALITSPSLGLalalvfviagiafKISAVPFHQWTPDVYE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  91 ASSWINCLTLMTWQKIA----PMMVLSYCIQLST----FMFFI-TIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMISS 161
Cdd:PRK02504  239 GSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDeqwkLLFTAlAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIG 318


                  ....
gi 2504469450 162 LIIG 165
Cdd:PRK02504  319 LVAG 322
PRK12650 PRK12650
DUF4040 family protein;
66-165 1.14e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 42.72  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  66 MMISSSLLLKIGAAPFHFWFPEVMGASSWINCLTLMTWQKIAPMMVLsycIQLSTFMFFITIMSVF----------IGAM 135
Cdd:PRK12650  212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLL---LRFSPVFHDVAVWNWLliivgmitalMGAV 288

                          90       100       110
                  ....*....|....*....|....*....|
gi 2504469450 136 GGLNQTSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:PRK12650  289 FAVQKTDLKKLTAYSTVSQLGWIVATIGVG 318
ndhB CHL00049
NADH dehydrogenase subunit 2
 21-166 2.00e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 41.53  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  21 KNTMTNESSIKYFIVQAMASTMLLF--------------------SILLIQMNNSMeweSEIIPSMMISSSLLLKIGAAP 80
Cdd:CHL00049  156 KDVRSNEATMKYLLMGGASSSILVYgfswlyglsggeielqeivnGLINTQMYNSP---GISIALIFITVGIGFKLSLAP 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  81 FHFWFPEVMGASSWINCLTLMTWQKIAPMM--------VLSYCIQLSTFMFFI-TIMSVFIGAMGGLNQTSLRQLLAYSS 151
Cdd:CHL00049  233 FHQWTPDVYEGSPTPVVAFLSVTSKVAASAlatrifdiPFYFSSNEWHLLLEIlAILSMILGNLIAITQTSMKRMLAYSS 312

                         170
                  ....*....|....*
gi 2504469450 152 ISHIGWMISSLIIGE 166
Cdd:CHL00049  313 IGQIGYVIIGIIVGD 327
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 28-159 3.02e-04

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 41.08  E-value: 3.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  28 SSIKYFIVQAMASTMLLFSILLIQMNNSMEWESEIIPSMMISSS----LLLKIGAA--------PFHFWFPEVMGASSWI 95
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGGGTFDLLELLNLPLPFGvqtwLFLAFFIAfavkvplfPLHTWLPDAHVEAPTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2504469450  96 NCLTLM-TWQKIAPMMVLSYCIQL--------STFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMI 159
Cdd:TIGR01972 237 GSVILAgVLLKMGTYGFLRFNLPLfpdaslyfAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 117-159 5.01e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 40.34  E-value: 5.01e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2504469450 117 QLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMI 159
Cdd:PRK12665  271 GLDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMV 313
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 6-165 1.49e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 38.98  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450   6 LEINLLSFIPLLANNKNTMTNESSIKYFIVQAMASTMLLFSILLI-------QMNNSMEWESEIIPSMMISSSLLLKIGA 78
Cdd:PRK08377  137 MEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSSFFLIGVALIygatgtlNMAHIAQLAGTIDPTVAQVGLALLIFGL 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2504469450  79 A------PFHFWFPEVMGA---------SSWINCLTLMTWQKIapMMVLSYCIQLSTFMFFITIM---SVFIGAMGGLNQ 140
Cdd:PRK08377  217 AveaelfPLNAWAPDAYQAaphpitvmfSAFVVKAGLYAMARI--LYLMQNANGWSSVLKLVIIMatlTVFFAELSALRQ 294

                         170       180
                  ....*....|....*....|....*
gi 2504469450 141 TSLRQLLAYSSISHIGWMISSLIIG 165
Cdd:PRK08377  295 KNVKRMIAYSSIGQVGMIALALALG 319
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 117-156 1.53e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 38.91  E-value: 1.53e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2504469450 117 QLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIG 156
Cdd:COG1008   273 YFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 117-159 7.63e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 36.72  E-value: 7.63e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2504469450 117 QLSTFMFFITIMSVFIGAMGGLNQTSLRQLLAYSSISHIGWMI 159
Cdd:PRK05846  275 EFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVT 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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