NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2508213545|gb|WHP53183|]
View 

PR domain-containing 9, partial [Mus musculus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
74-223 1.02e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.94  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545  74 KPYVCRECGRGFTQKSHLIKHQRT--HTGE--KPYVCRE--CGRGFTAKSNLIQHQRTHTGEKPYVCRECGRGFTTKSDL 147
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545 148 IK-------HQRTHTGEKPYVC--RECGRGFTQKSHLIKHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPY 216
Cdd:COG5048   368 NNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPL 447


                  ....*..
gi 2508213545 217 VCRECGR 223
Cdd:COG5048   448 LCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-139 1.00e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 1.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545   1 FSDKSNVNEHQKT--HTGE--KPYVCRE--CGRGFTAKSSLIQHQRTHTGEKPYVCRECGRGFTAKSSL-------IQHQ 67
Cdd:COG5048   299 FSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLnneppqsLQQY 378

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508213545  68 RTHTGEKPYVC--RECGRGFTQKSHLIKHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPYVCRECGR 139
Cdd:COG5048   379 KDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
226-295 7.92e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.92  E-value: 7.92e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508213545 226 TTKSDLIKHQRTHTGE----KPYVCRECGRGFTQKSHLIKHQRTHTGEKPYVCRECGRGFTQK--SDLIQHQTTHT 295
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHH 87
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
74-223 1.02e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.94  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545  74 KPYVCRECGRGFTQKSHLIKHQRT--HTGE--KPYVCRE--CGRGFTAKSNLIQHQRTHTGEKPYVCRECGRGFTTKSDL 147
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545 148 IK-------HQRTHTGEKPYVC--RECGRGFTQKSHLIKHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPY 216
Cdd:COG5048   368 NNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPL 447


                  ....*..
gi 2508213545 217 VCRECGR 223
Cdd:COG5048   448 LCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-139 1.00e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 1.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545   1 FSDKSNVNEHQKT--HTGE--KPYVCRE--CGRGFTAKSSLIQHQRTHTGEKPYVCRECGRGFTAKSSL-------IQHQ 67
Cdd:COG5048   299 FSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLnneppqsLQQY 378

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508213545  68 RTHTGEKPYVC--RECGRGFTQKSHLIKHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPYVCRECGR 139
Cdd:COG5048   379 KDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
226-295 7.92e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.92  E-value: 7.92e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508213545 226 TTKSDLIKHQRTHTGE----KPYVCRECGRGFTQKSHLIKHQRTHTGEKPYVCRECGRGFTQK--SDLIQHQTTHT 295
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHH 87
PHA00733 PHA00733
hypothetical protein
 19-66 4.14e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 4.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2508213545  19 PYVCRECGRGFTAKSSLIQHQRTHTGEKpyVCRECGRGFTAKSSLIQH 66
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
zf-H2C2_2 pfam13465
Zinc-finger double domain;
118-143 4.47e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 4.47e-03
                          10        20
                  ....*....|....*....|....*.
gi 2508213545 118 NLIQHQRTHTGEKPYVCRECGRGFTT 143
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
258-283 6.62e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.50  E-value: 6.62e-03
                          10        20
                  ....*....|....*....|....*.
gi 2508213545 258 HLIKHQRTHTGEKPYVCRECGRGFTQ 283
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
74-223 1.02e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.94  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545  74 KPYVCRECGRGFTQKSHLIKHQRT--HTGE--KPYVCRE--CGRGFTAKSNLIQHQRTHTGEKPYVCRECGRGFTTKSDL 147
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545 148 IK-------HQRTHTGEKPYVC--RECGRGFTQKSHLIKHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPY 216
Cdd:COG5048   368 NNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPL 447


                  ....*..
gi 2508213545 217 VCRECGR 223
Cdd:COG5048   448 LCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-139 1.00e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 1.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545   1 FSDKSNVNEHQKT--HTGE--KPYVCRE--CGRGFTAKSSLIQHQRTHTGEKPYVCRECGRGFTAKSSL-------IQHQ 67
Cdd:COG5048   299 FSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLnneppqsLQQY 378

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508213545  68 RTHTGEKPYVC--RECGRGFTQKSHLIKHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPYVCRECGR 139
Cdd:COG5048   379 KDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-295 1.09e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 1.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545   1 FSDKSNVNEHQKTHTGEKPYVCRECGRG--FTAKSSLIQHQRTHTGEKPYvcRECGRGFTAKSSLIQHQRTHTGEKP-YV 77
Cdd:COG5048    43 FSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSSLSSSSSNSnDN 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545  78 CRECGRGFTQKSHLIKHQ--RTHTGEKPYVCRECGRGF--TAKSNLIQHQRTHTgekpyvcRECGRGFTTKSDLIKHQRT 153
Cdd:COG5048   121 NLLSSHSLPPSSRDPQLPdlLSISNLRNNPLPGNNSSSvnTPQSNSLHPPLPAN-------SLSKDPSSNLSLLISSNVS 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545 154 HTGEKPYVCRECGRgFTQKSHLIKHQRTHTGEKPYVCRECGRGFTAKSNLIQHQRTHTGEKPYVCRECGRGFTTKSDLIK 233
Cdd:COG5048   194 TSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQS 272

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508213545 234 HQRTHTGE-------KPYVCRECGRGFTQKSHLIKHQRT--HTGE--KPYVCRE--CGRGFTQKSDLIQHQTTHT 295
Cdd:COG5048   273 SSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
142-215 7.43e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.00  E-value: 7.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508213545 142 TTKSDLIKHQRTHTGE----KPYVCRECGRGFTQKSHLIKHQRTHTGEKPYVCRECGRG--FTAKSNLIQHQRTHTGEKP 215
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPS 91
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
60-131 7.98e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.00  E-value: 7.98e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2508213545  60 KSSLIQHQRTHTGE----KPYVCRECGRGFTQKSHLIKHQRTHTGEKPYVCRECGRG--FTAKSNLIQHQRTHTGEKP 131
Cdd:COG5048    14 SVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPS 91
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
226-295 7.92e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.92  E-value: 7.92e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508213545 226 TTKSDLIKHQRTHTGE----KPYVCRECGRGFTQKSHLIKHQRTHTGEKPYVCRECGRGFTQK--SDLIQHQTTHT 295
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHH 87
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
91-159 2.51e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.29  E-value: 2.51e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508213545  91 LIKHQRTHTGE----KPYVCRECGRGFTAKSNLIQHQRTHTGEKPYVCRECGRG--FTTKSDLIKHQRTHTGEKP 159
Cdd:COG5048    17 SSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPS 91
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
175-243 2.51e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.29  E-value: 2.51e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508213545 175 LIKHQRTHTGE----KPYVCRECGRGFTAKSNLIQHQRTHTGEKPYVCRECGRG--FTTKSDLIKHQRTHTGEKP 243
Cdd:COG5048    17 SSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPS 91
PHA00733 PHA00733
hypothetical protein
 19-66 4.14e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 4.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2508213545  19 PYVCRECGRGFTAKSSLIQHQRTHTGEKpyVCRECGRGFTAKSSLIQH 66
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
zf-H2C2_2 pfam13465
Zinc-finger double domain;
118-143 4.47e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 4.47e-03
                          10        20
                  ....*....|....*....|....*.
gi 2508213545 118 NLIQHQRTHTGEKPYVCRECGRGFTT 143
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
202-227 4.47e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 4.47e-03
                          10        20
                  ....*....|....*....|....*.
gi 2508213545 202 NLIQHQRTHTGEKPYVCRECGRGFTT 227
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
258-283 6.62e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.50  E-value: 6.62e-03
                          10        20
                  ....*....|....*....|....*.
gi 2508213545 258 HLIKHQRTHTGEKPYVCRECGRGFTQ 283
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
62-87 8.30e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.11  E-value: 8.30e-03
                          10        20
                  ....*....|....*....|....*.
gi 2508213545  62 SLIQHQRTHTGEKPYVCRECGRGFTQ 87
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH