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Conserved domains on  [gi|501167513|ref|WP_012211512|]
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glycosyltransferase family 32 protein [Lactobacillus helveticus]

Protein Classification

glycosyltransferase family 32 protein( domain architecture ID 11467330)

glycosyltransferase family 32 protein similar to initiation-specific alpha-1,6-mannosyltransferase that is involved in outer chain elongation of asparagine-linked oligosaccharides of the type Man(9)GlcNAc(2)

CAZY:  GT32
EC:  2.4.-.-
PubMed:  11231017

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OCH1 COG3774
Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];
1-128 7.23e-50

Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442988 [Multi-domain]  Cd Length: 136  Bit Score: 159.28  E-value: 7.23e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501167513   1 MIPKIIHYVWVGHNPKSKIIRECIAIWKKNLPDYQFIEWNEDNFD----MHENKYIEQAYQAKKWAFVSDYVRARAIYEQ 76
Cdd:COG3774    2 MIPKIIHQTWFGDKELPELVQRCIASWKKLNPDWEYRLWDDENFDdfikEHGPEYLEAYYKLKKGAARADLFRLLLLYKY 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501167513  77 GGIYLDTDVRVIDDLTPLLK-DRAFIGFE--NKDYLSAAIFGAEKKHPFMQDILD 128
Cdd:COG3774   82 GGIYLDIDVECLKPLDPLLDgDDLFLGYEdpPPGIISNGFIAAEPGHPFLKKALE 136
 
Name Accession Description Interval E-value
OCH1 COG3774
Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];
1-128 7.23e-50

Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442988 [Multi-domain]  Cd Length: 136  Bit Score: 159.28  E-value: 7.23e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501167513   1 MIPKIIHYVWVGHNPKSKIIRECIAIWKKNLPDYQFIEWNEDNFD----MHENKYIEQAYQAKKWAFVSDYVRARAIYEQ 76
Cdd:COG3774    2 MIPKIIHQTWFGDKELPELVQRCIASWKKLNPDWEYRLWDDENFDdfikEHGPEYLEAYYKLKKGAARADLFRLLLLYKY 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501167513  77 GGIYLDTDVRVIDDLTPLLK-DRAFIGFE--NKDYLSAAIFGAEKKHPFMQDILD 128
Cdd:COG3774   82 GGIYLDIDVECLKPLDPLLDgDDLFLGYEdpPPGIISNGFIAAEPGHPFLKKALE 136
Gly_transf_sug pfam04488
Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short ...
 27-95 1.24e-09

Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases.


Pssm-ID: 398274 [Multi-domain]  Cd Length: 93  Bit Score: 53.49  E-value: 1.24e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501167513   27 WKKNLPDYQFIEWNEDNFDMHENKYIEQAY------QAKKWAFV--SDYVRARAIYEQGGIYLDTDVRVIDDLTPLL 95
Cdd:pfam04488  11 LIKLHPDYCYVVLSDDLDFALDINFLKSDTpwfleaYSLLPLFIakSDLLRYAILYKYGGIYLDTDVIPLKSLNSIG 87
 
Name Accession Description Interval E-value
OCH1 COG3774
Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];
1-128 7.23e-50

Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442988 [Multi-domain]  Cd Length: 136  Bit Score: 159.28  E-value: 7.23e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501167513   1 MIPKIIHYVWVGHNPKSKIIRECIAIWKKNLPDYQFIEWNEDNFD----MHENKYIEQAYQAKKWAFVSDYVRARAIYEQ 76
Cdd:COG3774    2 MIPKIIHQTWFGDKELPELVQRCIASWKKLNPDWEYRLWDDENFDdfikEHGPEYLEAYYKLKKGAARADLFRLLLLYKY 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501167513  77 GGIYLDTDVRVIDDLTPLLK-DRAFIGFE--NKDYLSAAIFGAEKKHPFMQDILD 128
Cdd:COG3774   82 GGIYLDIDVECLKPLDPLLDgDDLFLGYEdpPPGIISNGFIAAEPGHPFLKKALE 136
Gly_transf_sug pfam04488
Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short ...
 27-95 1.24e-09

Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases.


Pssm-ID: 398274 [Multi-domain]  Cd Length: 93  Bit Score: 53.49  E-value: 1.24e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501167513   27 WKKNLPDYQFIEWNEDNFDMHENKYIEQAY------QAKKWAFV--SDYVRARAIYEQGGIYLDTDVRVIDDLTPLL 95
Cdd:pfam04488  11 LIKLHPDYCYVVLSDDLDFALDINFLKSDTpwfleaYSLLPLFIakSDLLRYAILYKYGGIYLDTDVIPLKSLNSIG 87
Caps_synth pfam05704
Capsular polysaccharide synthesis protein; This family consists of several capsular ...
 18-138 1.65e-07

Capsular polysaccharide synthesis protein; This family consists of several capsular polysaccharide proteins. Capsular polysaccharide (CPS) is a major virulence factor in Streptococcus pneumoniae.


Pssm-ID: 368570  Cd Length: 278  Bit Score: 50.74  E-value: 1.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501167513   18 KIIRECIAIWKKNLPDYQFIEWNEDNF----DMHENkyIEQAYQAKKW--AFVSDYVRARAIYEQGGIYLDTDVRVIDDL 91
Cdd:pfam05704  63 EIVKKCIDSVKKNAPDYEVVLLTKDNIseyvDIPDF--IIEKFEKGKIsrAHFSDILRLNLLAKYGGVWIDATIYCTGDL 140

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 501167513   92 TPLLKDRAFIGFENKDYLSAAI---------FGAEKKHPFMQDILD----YYQDRSFEFD 138
Cdd:pfam05704 141 PNELLDSDFFTFSSSELDSNKIsisrwtgffLAAKKNNPLLSTLRDllleYWKKYNSLID 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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