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Conserved domains on  [gi|654070509|ref|WP_027709574|]
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hemopexin repeat-containing protein [Zooshikella ganghwensis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TcA_TcB_BD pfam18276
Tc toxin complex TcA C-terminal TcB-binding domain; This domain is found in the C-terminal ...
 3274-3565 2.07e-123

Tc toxin complex TcA C-terminal TcB-binding domain; This domain is found in the C-terminal region of the Tc toxin TcA, present in Photorhabdus luminescens. Tc Toxin complexes bind to the cell surface, are endocytosed and perforate the host endosomal membrane by forming channels that translocate toxic enzymes into the host. This domain is responsible for binding to toxin TcB. Binding of TcA to TcB/TcC opens the beta-propeller gate.


:

Pssm-ID: 465693  Cd Length: 287  Bit Score: 391.53  E-value: 2.07e-123
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3274 QIEGAKWSIKSAEQELVVHDKEVEHTKSMNTFMKEKFSNEQLYQWMTSKLSKLFFQTYQMAYDLAKGAEKAYIYENGLPA 3353
Cdd:pfam18276    2 QILAAEIRIAIAEKELENQQQQIENAAEVEDFLRTKFTNEELYSWMEGQLRALYYQAYDLALDLARQAERAFQFELGDTA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3354 SevNFIGSTYWDSLHKGLMSGDQLAYDLDRLEKYAIDNNSRGFEITKTISLAELDPIAFLKLKDKKECEFAFTEELFDYD 3433
Cdd:pfam18276   82 T--SFIQPGYWDSSRDGLLAGERLYLDLKRMEAAYLERNKREYEITKTVSLRQLDPLALLKLRATGKCEFSLPEWLFDLD 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3434 FPGHYNRQIKTVAIKF--VAGEGKVVNATLTQLSNKIVMKPDIKAVKYLinLNEEQPLSIRSDWRPTQQIAASQPDpyse 3511
Cdd:pfam18276  160 YPGHYMRRIKSVSVTIpcVAGPYTGVNATLTLLSSKYRISPDISGVDYL--EDGGDDPRFVTDLIPIQSIATSSGQ---- 233

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  3512 NSSGLFEVNFGDDRYLPFEGTGAVSRWRLELGGKKGSYELGEISDVQIEIQYTA 3565
Cdd:pfam18276  234 NDSGVFELNFRDERYLPFEGAGAISSWRLELPTEIRQFDYDTISDVILHLRYTA 287
ABC_toxin_N pfam20220
ABC toxin N-terminal region; This entry represents the region found N-terminal to the ...
 1371-1501 4.24e-52

ABC toxin N-terminal region; This entry represents the region found N-terminal to the neuraminidase domain in the pore forming ABC toxins.


:

Pssm-ID: 466371  Cd Length: 124  Bit Score: 180.15  E-value: 4.24e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1371 NKLNLMKRDALLEYSIhYCKNHQDEQYEDARDVYEDLLIDVKMGEIAETSRVKEAISALQLYFHRFFINLEEGNLKNTTD 1450
Cdd:pfam20220    1 DPLRESQRDALVAYLL-LSKAAAKQGIRDADDLYEYFLIDVQMSACVLTSRIKQAISSVQLYVQRCLLGLEPGVDLSSLD 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654070509  1451 PVsereslKEHWEWMKNYRVWEANRKVFLYPENYIRPELRDSKTPEFKTLE 1501
Cdd:pfam20220   80 RD------LTEWEWMKRYRVWEANRKIFLYPENWIDPELRDDKTPLFKELE 124
Neuraminidase pfam18413
Neuraminidase-like domain; This is a neuraminidase-like domain, which is structurally ...
 1531-1697 9.79e-32

Neuraminidase-like domain; This is a neuraminidase-like domain, which is structurally homologous to neuraminidases. It can be found in TcA subunit in tripartite Tc toxin complexes of bacterial pathogens. Functional analysis suggest that the neuraminidase-like domain acts as an electrostatic lock that opens at high or low pH values.


:

Pssm-ID: 465758  Cd Length: 170  Bit Score: 123.75  E-value: 9.79e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1531 LKIAGGYAYDKEANKEVL-LFGKTKEEPKKYYYRKATFIDGKSDNIQWKPWQEVQIQIGSDKVYPVYALNRFYVFWAEIE 1609
Cdd:pfam18413    1 LEVVSGYHDGTDPAEGTLhFFGRTRTAPYQYYYRTLDNSKGVLSANAWSPWEKIDLDIEGDYVRPVVFNGRLYLFWPEFE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1610 KKGNVRSDTnvsvSTDDDNTDIKSDAVIESVLQIYFSYqKSSGGWSAPQKLNYEIT-----SNDFITDYYLSFSGQDKAK 1684
Cdd:pfam18413   81 KKASSAKKT----GDDLGDQTVGSAVEKYWEIKLAWSE-YLDGSWSPPQVSSDSLTlsttgSEPDDSDLSDKLVALFASA 155

                          170
                   ....*....|...
gi 654070509  1685 SHGRESIIVSCYY 1697
Cdd:pfam18413  156 LYSADNLLLAVYK 168
HX super family cl02471
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-412 1.37e-20

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


The actual alignment was detected with superfamily member cd00094:

Pssm-ID: 413329 [Multi-domain]  Cd Length: 194  Bit Score: 92.37  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  205 IDATLSgLDGRTYIFSGEQYYRYSGkdyfQADPGYPRSVAEDWAGL-NTVEAAFTW--NGATYIFgednaKNKKYVRYst 281
Cdd:cd00094     9 FDAVTT-LRGELYFFKGRYFWRLSP----GKPPGSPFLISSFWPSLpSPVDAAFERpdTGKIYFF-----KGDKYWVY-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  282 nNYKEVDKGFPKPqeekktylwnlPTSFKKKTKGKGVDA-IFNAPDGKTYLFSGSDFIYYDETNRWWSEC--QLINENWK 358
Cdd:cd00094    77 -TGKNLEPGYPKP-----------ISDLGFPPTVKQIDAaLRWPDNGKTYFFKGDKYWRYDEKTQKMDPGypKLIETDFP 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  359 ALGDssSVKAAFTGKDQKTYIFvknsDGLQYYRFSDADYcKPDIGYPRPVGSFW 412
Cdd:cd00094   145 GVPD--KVDAAFRWLDGYYYFF----KGDQYWRFDPRSK-EVRVGYPLKISSDW 191
HX super family cl02471
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 12-247 2.65e-16

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


The actual alignment was detected with superfamily member cd00094:

Pssm-ID: 413329 [Multi-domain]  Cd Length: 194  Bit Score: 80.05  E-value: 2.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509   12 NIDAaVASDNGGTYFFKGDQFI---NSSNPDKICSIAEVWGK--EKIdvktlekaDAAY--AFEGKWYLFSGEHIFAYrd 84
Cdd:cd00094     8 SFDA-VTTLRGELYFFKGRYFWrlsPGKPPGSPFLISSFWPSlpSPV--------DAAFerPDTGKIYFFKGDKYWVY-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509   85 cienEGLEILEGYPKKISDYFGEKLPAKfhrdIDAALIIANSSnitKLYLFHDDEFVVGSLDRGNSEAGETGEIGEiget 164
Cdd:cd00094    77 ----TGKNLEPGYPKPISDLGFPPTVKQ----IDAALRWPDNG---KTYFFKGDKYWRYDEKTQKMDPGYPKLIET---- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  165 geaveasedgkdsvtklwtfndpqsvsIWGAITnlleqNGIDATLSGLDGRTYIFSGEQYYRYSGKDYfQADPGYPRSVA 244
Cdd:cd00094   142 ---------------------------DFPGVP-----DKVDAAFRWLDGYYYFFKGDQYWRFDPRSK-EVRVGYPLKIS 188


                  ...
gi 654070509  245 EDW 247
Cdd:cd00094   189 SDW 191
HX super family cl02471
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1152 1.23e-13

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


The actual alignment was detected with superfamily member cd00094:

Pssm-ID: 413329 [Multi-domain]  Cd Length: 194  Bit Score: 72.34  E-value: 1.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  997 IDAALLIPgntaKENKTYLFSGDQYFRYTGKGckkLEDGYPKRIglslagelSSTINPWFYKGIDAAVRCND-GSIYLFK 1075
Cdd:cd00094    53 VDAAFERP----DTGKIYFFKGDKYWVYTGKN---LEPGYPKPI--------SDLGFPPTVKQIDAALRWPDnGKTYFFK 117

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654070509 1076 NGKYQKQgdDLEdiSKTWGKRSNPFLKDQGYI--SQIDAAFIDADSGLIAIKGDQVVRYADTEQEyIEPGYPKALTDLF 1152
Cdd:cd00094   118 GDKYWRY--DEK--TQKMDPGYPKLIETDFPGvpDKVDAAFRWLDGYYYFFKGDQYWRFDPRSKE-VRVGYPLKISSDW 191
HX super family cl02471
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 311-537 1.51e-08

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


The actual alignment was detected with superfamily member cd00094:

Pssm-ID: 413329 [Multi-domain]  Cd Length: 194  Bit Score: 57.32  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  311 KKTKGKGVDAIFnAPDGKTYLFSGSDFIYYDETNRWWSECqLINENWKALgdSSSVKAAF-TGKDQKTYIFVknsdGLQY 389
Cdd:cd00094     2 DACDPLSFDAVT-TLRGELYFFKGRYFWRLSPGKPPGSPF-LISSFWPSL--PSPVDAAFeRPDTGKIYFFK----GDKY 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  390 YRFSDADyckPDIGYPRPVGSFWGniknqIADCNRVDAAVSLKSRElkekdngffdlketnHTYVFCRDQFYRYKSdtiq 469
Cdd:cd00094    74 WVYTGKN---LEPGYPKPISDLGF-----PPTVKQIDAALRWPDNG---------------KTYFFKGDKYWRYDE---- 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654070509  470 tkvrsETKKVETslsieaGYPKPIsqlmfEQRFQAlkhtpefmgdIADGIDAVM-SDERNVYLFKDSKV 537
Cdd:cd00094   127 -----KTQKMDP------GYPKLI-----ETDFPG----------VPDKVDAAFrWLDGYYYFFKGDQY 169
HX super family cl02471
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 770-908 8.32e-08

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


The actual alignment was detected with superfamily member cd00094:

Pssm-ID: 413329 [Multi-domain]  Cd Length: 194  Bit Score: 55.40  E-value: 8.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  770 HLVQQGWGHF----DTVFiENNHvsgEQTLIFIKDRKFLQYNvaGAHWFE--PKPLENL-WPKIPCHheifdkLETAFID 842
Cdd:cd00094    40 FLISSFWPSLpspvDAAF-ERPD---TGKIYFFKGDKYWVYT--GKNLEPgyPKPISDLgFPPTVKQ------IDAALRW 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654070509  843 PA-GKAHFFGNRCYVTYSKQSNALEEELAiSSKWGQLSAI-SKIDAAFVSLQGKTYLFSGEHYIRYSH 908
Cdd:cd00094   108 PDnGKTYFFKGDKYWRYDEKTQKMDPGYP-KLIETDFPGVpDKVDAAFRWLDGYYYFFKGDQYWRFDP 174
beta-trefoil_ABD_ABFB-like super family cl49624
Arabinose-binding domain (ABD), beta-trefoil fold, found in the ABFB family; The ABFB family ...
 1811-1909 1.35e-04

Arabinose-binding domain (ABD), beta-trefoil fold, found in the ABFB family; The ABFB family includes alpha-L-arabinofuranosidase B (ABF B)-like proteins and otogelin-like proteins. Alpha-L-arabinofuranosidase (EC 3.2.1.55), also called ABF, or non-reducing end alpha-L-arabinofuranosidase, or arabinofuranosidase, or arabinosidase, is involved in the degradation of arabinoxylan, a major component of plant hemicellulose. It can hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan. ABF belongs to the glycosyl hydrolase 54 family. Hungateiclostridium thermocellum anti-sigma-I factor RsgI5 shows high sequence similarity with ABF B. It negatively regulates SigI5 activity through direct interaction. The OTOG subfamily includes otogelin (OTOG) and otogelin-like protein (OTOGL). OTOG is a glycoprotein specific to acellular membranes of the inner ear. It may be required for the anchoring of otoconial membranes and cupula to the underlying neuroepithelia in the vestibule. OTOG may be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. OTOGL is a mucin glycoprotein that is a component of the tectorial membrane. It acts as a gel-forming mucin that forms high-molecular-weight complexes and is glycosylated through mucin-type O-glycosylation. Mutations in OTOG or OTOGL genes may cause hearing loss. Members of the ABFB family contain an ABD with a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. The ABD binds two arabinose molecules in the beta and gamma subdomains.


The actual alignment was detected with superfamily member cd23265:

Pssm-ID: 483964  Cd Length: 135  Bit Score: 44.58  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509 1811 NKNYVSFKSIENEKesYYMRHHADRIVLHRPDegDSreDVYNADTSFSVQKGLIGDGYTIYSIVNDGSvrvlYFDR--NG 1888
Cdd:cd23265    48 GEGTVSFESVDKPG--YYLRHRGGELRLEKND--GS--AAFREDATFRPRPGLADPGGVSFESVNYPG----YYLRhrNN 117

                          90       100
                  ....*....|....*....|.
gi 654070509 1889 CLWirlLSEINSLQEKRNATF 1909
Cdd:cd23265   118 RLV---LGKVDSTAFKEDATF 135
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 884-934 1.57e-04

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


:

Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 41.78  E-value: 1.57e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654070509   884 IDAAFVSLQGKTYLFSGEHYIRYSHADychVDAGYPKRVAEHlrsePGFEN 934
Cdd:pfam00045    1 IDAAFEDRDGKTYFFKGRKYWRFDPQR---VEPGYPKLISDF----PGLPC 44
 
Name Accession Description Interval E-value
TcA_TcB_BD pfam18276
Tc toxin complex TcA C-terminal TcB-binding domain; This domain is found in the C-terminal ...
 3274-3565 2.07e-123

Tc toxin complex TcA C-terminal TcB-binding domain; This domain is found in the C-terminal region of the Tc toxin TcA, present in Photorhabdus luminescens. Tc Toxin complexes bind to the cell surface, are endocytosed and perforate the host endosomal membrane by forming channels that translocate toxic enzymes into the host. This domain is responsible for binding to toxin TcB. Binding of TcA to TcB/TcC opens the beta-propeller gate.


Pssm-ID: 465693  Cd Length: 287  Bit Score: 391.53  E-value: 2.07e-123
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3274 QIEGAKWSIKSAEQELVVHDKEVEHTKSMNTFMKEKFSNEQLYQWMTSKLSKLFFQTYQMAYDLAKGAEKAYIYENGLPA 3353
Cdd:pfam18276    2 QILAAEIRIAIAEKELENQQQQIENAAEVEDFLRTKFTNEELYSWMEGQLRALYYQAYDLALDLARQAERAFQFELGDTA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3354 SevNFIGSTYWDSLHKGLMSGDQLAYDLDRLEKYAIDNNSRGFEITKTISLAELDPIAFLKLKDKKECEFAFTEELFDYD 3433
Cdd:pfam18276   82 T--SFIQPGYWDSSRDGLLAGERLYLDLKRMEAAYLERNKREYEITKTVSLRQLDPLALLKLRATGKCEFSLPEWLFDLD 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3434 FPGHYNRQIKTVAIKF--VAGEGKVVNATLTQLSNKIVMKPDIKAVKYLinLNEEQPLSIRSDWRPTQQIAASQPDpyse 3511
Cdd:pfam18276  160 YPGHYMRRIKSVSVTIpcVAGPYTGVNATLTLLSSKYRISPDISGVDYL--EDGGDDPRFVTDLIPIQSIATSSGQ---- 233

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  3512 NSSGLFEVNFGDDRYLPFEGTGAVSRWRLELGGKKGSYELGEISDVQIEIQYTA 3565
Cdd:pfam18276  234 NDSGVFELNFRDERYLPFEGAGAISSWRLELPTEIRQFDYDTISDVILHLRYTA 287
ABC_toxin_N pfam20220
ABC toxin N-terminal region; This entry represents the region found N-terminal to the ...
 1371-1501 4.24e-52

ABC toxin N-terminal region; This entry represents the region found N-terminal to the neuraminidase domain in the pore forming ABC toxins.


Pssm-ID: 466371  Cd Length: 124  Bit Score: 180.15  E-value: 4.24e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1371 NKLNLMKRDALLEYSIhYCKNHQDEQYEDARDVYEDLLIDVKMGEIAETSRVKEAISALQLYFHRFFINLEEGNLKNTTD 1450
Cdd:pfam20220    1 DPLRESQRDALVAYLL-LSKAAAKQGIRDADDLYEYFLIDVQMSACVLTSRIKQAISSVQLYVQRCLLGLEPGVDLSSLD 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654070509  1451 PVsereslKEHWEWMKNYRVWEANRKVFLYPENYIRPELRDSKTPEFKTLE 1501
Cdd:pfam20220   80 RD------LTEWEWMKRYRVWEANRKIFLYPENWIDPELRDDKTPLFKELE 124
Neuraminidase pfam18413
Neuraminidase-like domain; This is a neuraminidase-like domain, which is structurally ...
 1531-1697 9.79e-32

Neuraminidase-like domain; This is a neuraminidase-like domain, which is structurally homologous to neuraminidases. It can be found in TcA subunit in tripartite Tc toxin complexes of bacterial pathogens. Functional analysis suggest that the neuraminidase-like domain acts as an electrostatic lock that opens at high or low pH values.


Pssm-ID: 465758  Cd Length: 170  Bit Score: 123.75  E-value: 9.79e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1531 LKIAGGYAYDKEANKEVL-LFGKTKEEPKKYYYRKATFIDGKSDNIQWKPWQEVQIQIGSDKVYPVYALNRFYVFWAEIE 1609
Cdd:pfam18413    1 LEVVSGYHDGTDPAEGTLhFFGRTRTAPYQYYYRTLDNSKGVLSANAWSPWEKIDLDIEGDYVRPVVFNGRLYLFWPEFE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1610 KKGNVRSDTnvsvSTDDDNTDIKSDAVIESVLQIYFSYqKSSGGWSAPQKLNYEIT-----SNDFITDYYLSFSGQDKAK 1684
Cdd:pfam18413   81 KKASSAKKT----GDDLGDQTVGSAVEKYWEIKLAWSE-YLDGSWSPPQVSSDSLTlsttgSEPDDSDLSDKLVALFASA 155

                          170
                   ....*....|...
gi 654070509  1685 SHGRESIIVSCYY 1697
Cdd:pfam18413  156 LYSADNLLLAVYK 168
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-412 1.37e-20

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 92.37  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  205 IDATLSgLDGRTYIFSGEQYYRYSGkdyfQADPGYPRSVAEDWAGL-NTVEAAFTW--NGATYIFgednaKNKKYVRYst 281
Cdd:cd00094     9 FDAVTT-LRGELYFFKGRYFWRLSP----GKPPGSPFLISSFWPSLpSPVDAAFERpdTGKIYFF-----KGDKYWVY-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  282 nNYKEVDKGFPKPqeekktylwnlPTSFKKKTKGKGVDA-IFNAPDGKTYLFSGSDFIYYDETNRWWSEC--QLINENWK 358
Cdd:cd00094    77 -TGKNLEPGYPKP-----------ISDLGFPPTVKQIDAaLRWPDNGKTYFFKGDKYWRYDEKTQKMDPGypKLIETDFP 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  359 ALGDssSVKAAFTGKDQKTYIFvknsDGLQYYRFSDADYcKPDIGYPRPVGSFW 412
Cdd:cd00094   145 GVPD--KVDAAFRWLDGYYYFF----KGDQYWRFDPRSK-EVRVGYPLKISSDW 191
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 12-247 2.65e-16

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 80.05  E-value: 2.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509   12 NIDAaVASDNGGTYFFKGDQFI---NSSNPDKICSIAEVWGK--EKIdvktlekaDAAY--AFEGKWYLFSGEHIFAYrd 84
Cdd:cd00094     8 SFDA-VTTLRGELYFFKGRYFWrlsPGKPPGSPFLISSFWPSlpSPV--------DAAFerPDTGKIYFFKGDKYWVY-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509   85 cienEGLEILEGYPKKISDYFGEKLPAKfhrdIDAALIIANSSnitKLYLFHDDEFVVGSLDRGNSEAGETGEIGEiget 164
Cdd:cd00094    77 ----TGKNLEPGYPKPISDLGFPPTVKQ----IDAALRWPDNG---KTYFFKGDKYWRYDEKTQKMDPGYPKLIET---- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  165 geaveasedgkdsvtklwtfndpqsvsIWGAITnlleqNGIDATLSGLDGRTYIFSGEQYYRYSGKDYfQADPGYPRSVA 244
Cdd:cd00094   142 ---------------------------DFPGVP-----DKVDAAFRWLDGYYYFFKGDQYWRFDPRSK-EVRVGYPLKIS 188


                  ...
gi 654070509  245 EDW 247
Cdd:cd00094   189 SDW 191
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1152 1.23e-13

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 72.34  E-value: 1.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  997 IDAALLIPgntaKENKTYLFSGDQYFRYTGKGckkLEDGYPKRIglslagelSSTINPWFYKGIDAAVRCND-GSIYLFK 1075
Cdd:cd00094    53 VDAAFERP----DTGKIYFFKGDKYWVYTGKN---LEPGYPKPI--------SDLGFPPTVKQIDAALRWPDnGKTYFFK 117

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654070509 1076 NGKYQKQgdDLEdiSKTWGKRSNPFLKDQGYI--SQIDAAFIDADSGLIAIKGDQVVRYADTEQEyIEPGYPKALTDLF 1152
Cdd:cd00094   118 GDKYWRY--DEK--TQKMDPGYPKLIETDFPGvpDKVDAAFRWLDGYYYFFKGDQYWRFDPRSKE-VRVGYPLKISSDW 191
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 311-537 1.51e-08

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 57.32  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  311 KKTKGKGVDAIFnAPDGKTYLFSGSDFIYYDETNRWWSECqLINENWKALgdSSSVKAAF-TGKDQKTYIFVknsdGLQY 389
Cdd:cd00094     2 DACDPLSFDAVT-TLRGELYFFKGRYFWRLSPGKPPGSPF-LISSFWPSL--PSPVDAAFeRPDTGKIYFFK----GDKY 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  390 YRFSDADyckPDIGYPRPVGSFWGniknqIADCNRVDAAVSLKSRElkekdngffdlketnHTYVFCRDQFYRYKSdtiq 469
Cdd:cd00094    74 WVYTGKN---LEPGYPKPISDLGF-----PPTVKQIDAALRWPDNG---------------KTYFFKGDKYWRYDE---- 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654070509  470 tkvrsETKKVETslsieaGYPKPIsqlmfEQRFQAlkhtpefmgdIADGIDAVM-SDERNVYLFKDSKV 537
Cdd:cd00094   127 -----KTQKMDP------GYPKLI-----ETDFPG----------VPDKVDAAFrWLDGYYYFFKGDQY 169
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 770-908 8.32e-08

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 55.40  E-value: 8.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  770 HLVQQGWGHF----DTVFiENNHvsgEQTLIFIKDRKFLQYNvaGAHWFE--PKPLENL-WPKIPCHheifdkLETAFID 842
Cdd:cd00094    40 FLISSFWPSLpspvDAAF-ERPD---TGKIYFFKGDKYWVYT--GKNLEPgyPKPISDLgFPPTVKQ------IDAALRW 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654070509  843 PA-GKAHFFGNRCYVTYSKQSNALEEELAiSSKWGQLSAI-SKIDAAFVSLQGKTYLFSGEHYIRYSH 908
Cdd:cd00094   108 PDnGKTYFFKGDKYWRYDEKTQKMDPGYP-KLIETDFPGVpDKVDAAFRWLDGYYYFFKGDQYWRFDP 174
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-251 1.33e-07

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 50.32  E-value: 1.33e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 654070509    205 IDATLSGLDGRTYIFSGEQYYRYsgkDYFQADPGYPRSVAEDWAGLN 251
Cdd:smart00120    1 IDAAFELRDGKTYFFKGDKYWRF---DPKRVDPGYPKLISSFFPGLP 44
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-247 2.06e-05

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 44.09  E-value: 2.06e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 654070509   205 IDATLSGLDGRTYIFSGEQYYRYsgkDYFQADPGYPRSVAEDW 247
Cdd:pfam00045    1 IDAAFEDRDGKTYFFKGRKYWRF---DPQRVEPGYPKLISDFP 40
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1040 5.19e-05

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 43.00  E-value: 5.19e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 654070509    997 IDAALLIPGNtakenKTYLFSGDQYFRYTGkgcKKLEDGYPKRI 1040
Cdd:smart00120    1 IDAAFELRDG-----KTYFFKGDKYWRFDP---KRVDPGYPKLI 36
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1040 7.60e-05

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 42.55  E-value: 7.60e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 654070509   997 IDAALlipgnTAKENKTYLFSGDQYFRYTGkgcKKLEDGYPKRI 1040
Cdd:pfam00045    1 IDAAF-----EDRDGKTYFFKGRKYWRFDP---QRVEPGYPKLI 36
beta-trefoil_ABD_ABFB-like cd23265
Arabinose-binding domain (ABD), beta-trefoil fold, found in the ABFB family; The ABFB family ...
 1811-1909 1.35e-04

Arabinose-binding domain (ABD), beta-trefoil fold, found in the ABFB family; The ABFB family includes alpha-L-arabinofuranosidase B (ABF B)-like proteins and otogelin-like proteins. Alpha-L-arabinofuranosidase (EC 3.2.1.55), also called ABF, or non-reducing end alpha-L-arabinofuranosidase, or arabinofuranosidase, or arabinosidase, is involved in the degradation of arabinoxylan, a major component of plant hemicellulose. It can hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan. ABF belongs to the glycosyl hydrolase 54 family. Hungateiclostridium thermocellum anti-sigma-I factor RsgI5 shows high sequence similarity with ABF B. It negatively regulates SigI5 activity through direct interaction. The OTOG subfamily includes otogelin (OTOG) and otogelin-like protein (OTOGL). OTOG is a glycoprotein specific to acellular membranes of the inner ear. It may be required for the anchoring of otoconial membranes and cupula to the underlying neuroepithelia in the vestibule. OTOG may be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. OTOGL is a mucin glycoprotein that is a component of the tectorial membrane. It acts as a gel-forming mucin that forms high-molecular-weight complexes and is glycosylated through mucin-type O-glycosylation. Mutations in OTOG or OTOGL genes may cause hearing loss. Members of the ABFB family contain an ABD with a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. The ABD binds two arabinose molecules in the beta and gamma subdomains.


Pssm-ID: 467807  Cd Length: 135  Bit Score: 44.58  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509 1811 NKNYVSFKSIENEKesYYMRHHADRIVLHRPDegDSreDVYNADTSFSVQKGLIGDGYTIYSIVNDGSvrvlYFDR--NG 1888
Cdd:cd23265    48 GEGTVSFESVDKPG--YYLRHRGGELRLEKND--GS--AAFREDATFRPRPGLADPGGVSFESVNYPG----YYLRhrNN 117

                          90       100
                  ....*....|....*....|.
gi 654070509 1889 CLWirlLSEINSLQEKRNATF 1909
Cdd:cd23265   118 RLV---LGKVDSTAFKEDATF 135
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 884-934 1.57e-04

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 41.78  E-value: 1.57e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654070509   884 IDAAFVSLQGKTYLFSGEHYIRYSHADychVDAGYPKRVAEHlrsePGFEN 934
Cdd:pfam00045    1 IDAAFEDRDGKTYFFKGRKYWRFDPQR---VEPGYPKLISDF----PGLPC 44
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 884-932 1.05e-03

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 39.15  E-value: 1.05e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*....
gi 654070509    884 IDAAFVSLQGKTYLFSGEHYIRYshaDYCHVDAGYPKRVAehlRSEPGF 932
Cdd:smart00120    1 IDAAFELRDGKTYFFKGDKYWRF---DPKRVDPGYPKLIS---SFFPGL 43
 
Name Accession Description Interval E-value
TcA_TcB_BD pfam18276
Tc toxin complex TcA C-terminal TcB-binding domain; This domain is found in the C-terminal ...
 3274-3565 2.07e-123

Tc toxin complex TcA C-terminal TcB-binding domain; This domain is found in the C-terminal region of the Tc toxin TcA, present in Photorhabdus luminescens. Tc Toxin complexes bind to the cell surface, are endocytosed and perforate the host endosomal membrane by forming channels that translocate toxic enzymes into the host. This domain is responsible for binding to toxin TcB. Binding of TcA to TcB/TcC opens the beta-propeller gate.


Pssm-ID: 465693  Cd Length: 287  Bit Score: 391.53  E-value: 2.07e-123
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3274 QIEGAKWSIKSAEQELVVHDKEVEHTKSMNTFMKEKFSNEQLYQWMTSKLSKLFFQTYQMAYDLAKGAEKAYIYENGLPA 3353
Cdd:pfam18276    2 QILAAEIRIAIAEKELENQQQQIENAAEVEDFLRTKFTNEELYSWMEGQLRALYYQAYDLALDLARQAERAFQFELGDTA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3354 SevNFIGSTYWDSLHKGLMSGDQLAYDLDRLEKYAIDNNSRGFEITKTISLAELDPIAFLKLKDKKECEFAFTEELFDYD 3433
Cdd:pfam18276   82 T--SFIQPGYWDSSRDGLLAGERLYLDLKRMEAAYLERNKREYEITKTVSLRQLDPLALLKLRATGKCEFSLPEWLFDLD 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  3434 FPGHYNRQIKTVAIKF--VAGEGKVVNATLTQLSNKIVMKPDIKAVKYLinLNEEQPLSIRSDWRPTQQIAASQPDpyse 3511
Cdd:pfam18276  160 YPGHYMRRIKSVSVTIpcVAGPYTGVNATLTLLSSKYRISPDISGVDYL--EDGGDDPRFVTDLIPIQSIATSSGQ---- 233

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  3512 NSSGLFEVNFGDDRYLPFEGTGAVSRWRLELGGKKGSYELGEISDVQIEIQYTA 3565
Cdd:pfam18276  234 NDSGVFELNFRDERYLPFEGAGAISSWRLELPTEIRQFDYDTISDVILHLRYTA 287
ABC_toxin_N pfam20220
ABC toxin N-terminal region; This entry represents the region found N-terminal to the ...
 1371-1501 4.24e-52

ABC toxin N-terminal region; This entry represents the region found N-terminal to the neuraminidase domain in the pore forming ABC toxins.


Pssm-ID: 466371  Cd Length: 124  Bit Score: 180.15  E-value: 4.24e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1371 NKLNLMKRDALLEYSIhYCKNHQDEQYEDARDVYEDLLIDVKMGEIAETSRVKEAISALQLYFHRFFINLEEGNLKNTTD 1450
Cdd:pfam20220    1 DPLRESQRDALVAYLL-LSKAAAKQGIRDADDLYEYFLIDVQMSACVLTSRIKQAISSVQLYVQRCLLGLEPGVDLSSLD 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654070509  1451 PVsereslKEHWEWMKNYRVWEANRKVFLYPENYIRPELRDSKTPEFKTLE 1501
Cdd:pfam20220   80 RD------LTEWEWMKRYRVWEANRKIFLYPENWIDPELRDDKTPLFKELE 124
Neuraminidase pfam18413
Neuraminidase-like domain; This is a neuraminidase-like domain, which is structurally ...
 1531-1697 9.79e-32

Neuraminidase-like domain; This is a neuraminidase-like domain, which is structurally homologous to neuraminidases. It can be found in TcA subunit in tripartite Tc toxin complexes of bacterial pathogens. Functional analysis suggest that the neuraminidase-like domain acts as an electrostatic lock that opens at high or low pH values.


Pssm-ID: 465758  Cd Length: 170  Bit Score: 123.75  E-value: 9.79e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1531 LKIAGGYAYDKEANKEVL-LFGKTKEEPKKYYYRKATFIDGKSDNIQWKPWQEVQIQIGSDKVYPVYALNRFYVFWAEIE 1609
Cdd:pfam18413    1 LEVVSGYHDGTDPAEGTLhFFGRTRTAPYQYYYRTLDNSKGVLSANAWSPWEKIDLDIEGDYVRPVVFNGRLYLFWPEFE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  1610 KKGNVRSDTnvsvSTDDDNTDIKSDAVIESVLQIYFSYqKSSGGWSAPQKLNYEIT-----SNDFITDYYLSFSGQDKAK 1684
Cdd:pfam18413   81 KKASSAKKT----GDDLGDQTVGSAVEKYWEIKLAWSE-YLDGSWSPPQVSSDSLTlsttgSEPDDSDLSDKLVALFASA 155

                          170
                   ....*....|...
gi 654070509  1685 SHGRESIIVSCYY 1697
Cdd:pfam18413  156 LYSADNLLLAVYK 168
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-412 1.37e-20

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 92.37  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  205 IDATLSgLDGRTYIFSGEQYYRYSGkdyfQADPGYPRSVAEDWAGL-NTVEAAFTW--NGATYIFgednaKNKKYVRYst 281
Cdd:cd00094     9 FDAVTT-LRGELYFFKGRYFWRLSP----GKPPGSPFLISSFWPSLpSPVDAAFERpdTGKIYFF-----KGDKYWVY-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  282 nNYKEVDKGFPKPqeekktylwnlPTSFKKKTKGKGVDA-IFNAPDGKTYLFSGSDFIYYDETNRWWSEC--QLINENWK 358
Cdd:cd00094    77 -TGKNLEPGYPKP-----------ISDLGFPPTVKQIDAaLRWPDNGKTYFFKGDKYWRYDEKTQKMDPGypKLIETDFP 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  359 ALGDssSVKAAFTGKDQKTYIFvknsDGLQYYRFSDADYcKPDIGYPRPVGSFW 412
Cdd:cd00094   145 GVPD--KVDAAFRWLDGYYYFF----KGDQYWRFDPRSK-EVRVGYPLKISSDW 191
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 12-247 2.65e-16

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 80.05  E-value: 2.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509   12 NIDAaVASDNGGTYFFKGDQFI---NSSNPDKICSIAEVWGK--EKIdvktlekaDAAY--AFEGKWYLFSGEHIFAYrd 84
Cdd:cd00094     8 SFDA-VTTLRGELYFFKGRYFWrlsPGKPPGSPFLISSFWPSlpSPV--------DAAFerPDTGKIYFFKGDKYWVY-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509   85 cienEGLEILEGYPKKISDYFGEKLPAKfhrdIDAALIIANSSnitKLYLFHDDEFVVGSLDRGNSEAGETGEIGEiget 164
Cdd:cd00094    77 ----TGKNLEPGYPKPISDLGFPPTVKQ----IDAALRWPDNG---KTYFFKGDKYWRYDEKTQKMDPGYPKLIET---- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  165 geaveasedgkdsvtklwtfndpqsvsIWGAITnlleqNGIDATLSGLDGRTYIFSGEQYYRYSGKDYfQADPGYPRSVA 244
Cdd:cd00094   142 ---------------------------DFPGVP-----DKVDAAFRWLDGYYYFFKGDQYWRFDPRSK-EVRVGYPLKIS 188


                  ...
gi 654070509  245 EDW 247
Cdd:cd00094   189 SDW 191
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1152 1.23e-13

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 72.34  E-value: 1.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  997 IDAALLIPgntaKENKTYLFSGDQYFRYTGKGckkLEDGYPKRIglslagelSSTINPWFYKGIDAAVRCND-GSIYLFK 1075
Cdd:cd00094    53 VDAAFERP----DTGKIYFFKGDKYWVYTGKN---LEPGYPKPI--------SDLGFPPTVKQIDAALRWPDnGKTYFFK 117

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654070509 1076 NGKYQKQgdDLEdiSKTWGKRSNPFLKDQGYI--SQIDAAFIDADSGLIAIKGDQVVRYADTEQEyIEPGYPKALTDLF 1152
Cdd:cd00094   118 GDKYWRY--DEK--TQKMDPGYPKLIETDFPGvpDKVDAAFRWLDGYYYFFKGDQYWRFDPRSKE-VRVGYPLKISSDW 191
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1192 4.36e-09

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 58.86  E-value: 4.36e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  997 IDAALLIPGntakenKTYLFSGDQYFRYTGkgckKLEDGYPKRIGlSLAGELSStinpwfykGIDAAV-RCNDGSIYLFK 1075
Cdd:cd00094     9 FDAVTTLRG------ELYFFKGRYFWRLSP----GKPPGSPFLIS-SFWPSLPS--------PVDAAFeRPDTGKIYFFK 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509 1076 NGKYQKQ-GDDLE-----DISKTwgkrsnPFLKDQGyisQIDAAFIDADSGLIAI-KGDQVVRYaDTEQEYIEPGYPKAL 1148
Cdd:cd00094    70 GDKYWVYtGKNLEpgypkPISDL------GFPPTVK---QIDAALRWPDNGKTYFfKGDKYWRY-DEKTQKMDPGYPKLI 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 654070509 1149 TDLFHQLPDNyqngVNSAFTY-AGRLYLLKKK------DKNKENQTTYIRY 1192
Cdd:cd00094   140 ETDFPGVPDK----VDAAFRWlDGYYYFFKGDqywrfdPRSKEVRVGYPLK 186
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 311-537 1.51e-08

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 57.32  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  311 KKTKGKGVDAIFnAPDGKTYLFSGSDFIYYDETNRWWSECqLINENWKALgdSSSVKAAF-TGKDQKTYIFVknsdGLQY 389
Cdd:cd00094     2 DACDPLSFDAVT-TLRGELYFFKGRYFWRLSPGKPPGSPF-LISSFWPSL--PSPVDAAFeRPDTGKIYFFK----GDKY 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  390 YRFSDADyckPDIGYPRPVGSFWGniknqIADCNRVDAAVSLKSRElkekdngffdlketnHTYVFCRDQFYRYKSdtiq 469
Cdd:cd00094    74 WVYTGKN---LEPGYPKPISDLGF-----PPTVKQIDAALRWPDNG---------------KTYFFKGDKYWRYDE---- 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654070509  470 tkvrsETKKVETslsieaGYPKPIsqlmfEQRFQAlkhtpefmgdIADGIDAVM-SDERNVYLFKDSKV 537
Cdd:cd00094   127 -----KTQKMDP------GYPKLI-----ETDFPG----------VPDKVDAAFrWLDGYYYFFKGDQY 169
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 770-908 8.32e-08

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 55.40  E-value: 8.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  770 HLVQQGWGHF----DTVFiENNHvsgEQTLIFIKDRKFLQYNvaGAHWFE--PKPLENL-WPKIPCHheifdkLETAFID 842
Cdd:cd00094    40 FLISSFWPSLpspvDAAF-ERPD---TGKIYFFKGDKYWVYT--GKNLEPgyPKPISDLgFPPTVKQ------IDAALRW 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654070509  843 PA-GKAHFFGNRCYVTYSKQSNALEEELAiSSKWGQLSAI-SKIDAAFVSLQGKTYLFSGEHYIRYSH 908
Cdd:cd00094   108 PDnGKTYFFKGDKYWRYDEKTQKMDPGYP-KLIETDFPGVpDKVDAAFRWLDGYYYFFKGDQYWRFDP 174
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-251 1.33e-07

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 50.32  E-value: 1.33e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 654070509    205 IDATLSGLDGRTYIFSGEQYYRYsgkDYFQADPGYPRSVAEDWAGLN 251
Cdd:smart00120    1 IDAAFELRDGKTYFFKGDKYWRF---DPKRVDPGYPKLISSFFPGLP 44
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 205-247 2.06e-05

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 44.09  E-value: 2.06e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 654070509   205 IDATLSGLDGRTYIFSGEQYYRYsgkDYFQADPGYPRSVAEDW 247
Cdd:pfam00045    1 IDAAFEDRDGKTYFFKGRKYWRF---DPQRVEPGYPKLISDFP 40
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 4-105 4.61e-05

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 47.31  E-value: 4.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509    4 GLPENFKgNIDAAVAS-DNGGTYFFKGDQFI------NSSNPDKICSIAEVW-GKEkidvktlEKADAAYAFE-GKWYLF 74
Cdd:cd00094    93 GFPPTVK-QIDAALRWpDNGKTYFFKGDKYWrydektQKMDPGYPKLIETDFpGVP-------DKVDAAFRWLdGYYYFF 164

                          90       100       110
                  ....*....|....*....|....*....|.
gi 654070509   75 SGEHIFAYrdciENEGLEILEGYPKKISDYF 105
Cdd:cd00094   165 KGDQYWRF----DPRSKEVRVGYPLKISSDW 191
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1040 5.19e-05

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 43.00  E-value: 5.19e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 654070509    997 IDAALLIPGNtakenKTYLFSGDQYFRYTGkgcKKLEDGYPKRI 1040
Cdd:smart00120    1 IDAAFELRDG-----KTYFFKGDKYWRFDP---KRVDPGYPKLI 36
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 362-646 5.20e-05

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 46.92  E-value: 5.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  362 DSSSVKAAFTGkDQKTYIFVKNsdglQYYRFSDAdycKPDiGYPRPVGSFWGNIKNqiadcnRVDAAvslksrelkekdn 441
Cdd:cd00094     5 DPLSFDAVTTL-RGELYFFKGR----YFWRLSPG---KPP-GSPFLISSFWPSLPS------PVDAA------------- 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  442 gfFDLKETNHTYVFCRDQFYRYKSDTIqtkvrsetkkvetslsiEAGYPKPISQLMFeqrfqalkhtpefmGDIADGIDA 521
Cdd:cd00094    57 --FERPDTGKIYFFKGDKYWVYTGKNL-----------------EPGYPKPISDLGF--------------PPTVKQIDA 103

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509  522 VMSDERN--VYLFKDSKVqilsdhchadiHHFNglEKAIVMENGEifgigsvgesgqtwrhisslegtggivLGQPGEMP 599
Cdd:cd00094   104 ALRWPDNgkTYFFKGDKY-----------WRYD--EKTQKMDPGY---------------------------PKLIETDF 143

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 654070509  600 AWLadikksENEIDAVLQGTDHNTYVFTGK-----NFLNKQLNREY--KIASYW 646
Cdd:cd00094   144 PGV------PDKVDAAFRWLDGYYYFFKGDqywrfDPRSKEVRVGYplKISSDW 191
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 997-1040 7.60e-05

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 42.55  E-value: 7.60e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 654070509   997 IDAALlipgnTAKENKTYLFSGDQYFRYTGkgcKKLEDGYPKRI 1040
Cdd:pfam00045    1 IDAAF-----EDRDGKTYFFKGRKYWRFDP---QRVEPGYPKLI 36
beta-trefoil_ABD_ABFB-like cd23265
Arabinose-binding domain (ABD), beta-trefoil fold, found in the ABFB family; The ABFB family ...
 1811-1909 1.35e-04

Arabinose-binding domain (ABD), beta-trefoil fold, found in the ABFB family; The ABFB family includes alpha-L-arabinofuranosidase B (ABF B)-like proteins and otogelin-like proteins. Alpha-L-arabinofuranosidase (EC 3.2.1.55), also called ABF, or non-reducing end alpha-L-arabinofuranosidase, or arabinofuranosidase, or arabinosidase, is involved in the degradation of arabinoxylan, a major component of plant hemicellulose. It can hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan. ABF belongs to the glycosyl hydrolase 54 family. Hungateiclostridium thermocellum anti-sigma-I factor RsgI5 shows high sequence similarity with ABF B. It negatively regulates SigI5 activity through direct interaction. The OTOG subfamily includes otogelin (OTOG) and otogelin-like protein (OTOGL). OTOG is a glycoprotein specific to acellular membranes of the inner ear. It may be required for the anchoring of otoconial membranes and cupula to the underlying neuroepithelia in the vestibule. OTOG may be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. OTOGL is a mucin glycoprotein that is a component of the tectorial membrane. It acts as a gel-forming mucin that forms high-molecular-weight complexes and is glycosylated through mucin-type O-glycosylation. Mutations in OTOG or OTOGL genes may cause hearing loss. Members of the ABFB family contain an ABD with a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. The ABD binds two arabinose molecules in the beta and gamma subdomains.


Pssm-ID: 467807  Cd Length: 135  Bit Score: 44.58  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654070509 1811 NKNYVSFKSIENEKesYYMRHHADRIVLHRPDegDSreDVYNADTSFSVQKGLIGDGYTIYSIVNDGSvrvlYFDR--NG 1888
Cdd:cd23265    48 GEGTVSFESVDKPG--YYLRHRGGELRLEKND--GS--AAFREDATFRPRPGLADPGGVSFESVNYPG----YYLRhrNN 117

                          90       100
                  ....*....|....*....|.
gi 654070509 1889 CLWirlLSEINSLQEKRNATF 1909
Cdd:cd23265   118 RLV---LGKVDSTAFKEDATF 135
Hemopexin pfam00045
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 884-934 1.57e-04

Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).


Pssm-ID: 395000 [Multi-domain]  Cd Length: 44  Bit Score: 41.78  E-value: 1.57e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654070509   884 IDAAFVSLQGKTYLFSGEHYIRYSHADychVDAGYPKRVAEHlrsePGFEN 934
Cdd:pfam00045    1 IDAAFEDRDGKTYFFKGRKYWRFDPQR---VEPGYPKLISDF----PGLPC 44
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 884-932 1.05e-03

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 39.15  E-value: 1.05e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*....
gi 654070509    884 IDAAFVSLQGKTYLFSGEHYIRYshaDYCHVDAGYPKRVAehlRSEPGF 932
Cdd:smart00120    1 IDAAFELRDGKTYFFKGDKYWRF---DPKRVDPGYPKLIS---SFFPGL 43
HX smart00120
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 368-415 8.91e-03

Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs).


Pssm-ID: 214524 [Multi-domain]  Cd Length: 45  Bit Score: 36.84  E-value: 8.91e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 654070509    368 AAFTGKDQKTYIFVKNsdglQYYRFSDAdycKPDIGYPRPVGSFWGNI 415
Cdd:smart00120    3 AAFELRDGKTYFFKGD----KYWRFDPK---RVDPGYPKLISSFFPGL 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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