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MULTISPECIES: PD-(D/E)XK nuclease family protein [Lactiplantibacillus]
Protein Classification
PD-(D/E)XK nuclease family protein ( domain architecture ID 11467507 )
PD-(D/E)XK nuclease family protein similar to ATP-dependent helicase/deoxyribonuclease subunit B (AddB), part of a heterodimer that acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease
List of domain hits
Name
Accession
Description
Interval
E-value
AddB
COG3857
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1180
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
:Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 820.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 4 Q F V LG P A KMDHRRTMVAQLVAT L ma K PQDQFFY LVP NHIK F DT E VDV L N RL aqafgqp D L YAQTQV QV F SF T RLAW YLMK 83
Cdd:COG3857 1 R F I LG R A GSGKTTYLLEEIKEE L -- K EGKPIIL LVP EQMT F QA E RAL L K RL ------- G L GGSIRA QV L SF S RLAW RVLQ 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 84 NEAAYQV P R LS A AG ID MLL YR IL QR H A DEL RL F GGEISQT GF VT QLA RE I N EL QTANLQ PED VVQL A AN aqagd L QA KL H 163
Cdd:COG3857 72 ETGGATR P L LS D AG KR MLL RK IL EE H K DEL KV F ARAADKP GF IE QLA EL I T EL KRYGIT PED LEEA A EL ----- L KE KL R 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 164 DLA IV Y KDFVAAT A DK Y LKPA D I L VQ L NAY L RRQD - L H G THV Y VE la GF AQLPA QE QGIVTTM L EQGAD VTI S L M LD hkv 242
Cdd:COG3857 147 DLA LI Y EAYEEKL A GR Y IDSE D L L RL L AEK L EKSE f L E G AEI Y ID -- GF TDFTP QE LELLEAL L KKAKE VTI T L T LD --- 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 243 vdra P ENGT LF YQS G RL Y Y RL YQY A RIRQIP V SQ diyaetp RVA P G L VA L DDFWRGQ P Q aatgy EE PNTNVHLFRTDS R Q 322
Cdd:COG3857 222 ---- P DELD LF SAT G ET Y E RL LEL A KENGVE V EF ------- KKS P E L AH L ERNLFAY P P ----- EE EPEGIEIIEAAN R R 285
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 323 T E LAQ V G R M IR AM V A kkhadp ADD Y H YRD FLIMT R H L D AY QTMLAPT F H E LE IPYF V D LQ R SMAD HPLVELI NA L FDIDA 402
Cdd:COG3857 286 A E VEA V A R E IR RL V R ------ EEG Y R YRD IAVVV R D L E AY APLIERV F A E YG IPYF I D EK R PLSH HPLVELI LS L LELVR 359
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 403 QQYQ Y R DV M R V LKT E LL mpningqpmd R QAY R QAV D LT EN FI L KS G YH G Q RW VQ R edwqyfql TEGDAGVE TD QNA E ISR 482
Cdd:COG3857 360 SNFR Y E DV F R L LKT G LL ---------- R PLS R EEI D RL EN YV L AY G IR G R RW LE R -------- YLEEEEEL TD EEE E DLE 421
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 483 QI N LIHHFVA E T L P P FFKKMRQ A PDGKAAVTL L VN FL TSQ GV TDQ L LA WR d Q A LDRQ D VRA A A E P EQ T W QTFCGM LDE Y V 562
Cdd:COG3857 422 RL N ELRDRLL E P L L P LRERLKK A KTVREWAEA L YE FL EEL GV PEK L EE WR - E A EEAG D LEE A R E H EQ A W NALIEL LDE L V 500
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 563 TI LG A E PFEITD FL AL L QA G F E GASYSQ IP ST LDQV LISESGMVQSQ D H K V VF MV G ATDL V M P D R IMTNN LLSD VDK E N L 642
Cdd:COG3857 501 EV LG D E KLSLEE FL RI L ES G L E ELTFGL IP PS LDQV QVGGLDRARGL D F K A VF VL G LNEG V F P A R PREDG LLSD EER E R L 580
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 643 Q ptlssl DGDHY L NDSAVVQ L GD E SC L N Y L A FLS A RRH L FF S A PL K D DQETD L NW S NYVR R IQRQ F NLR E HT ylgtpd PT 722
Cdd:COG3857 581 N ------ ELGLE L PPTSRER L LE E RF L F Y R A LTR A SER L YL S Y PL A D EEGKA L LP S PLID R LREL F PEL E ER ------ SL 648
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 723 NADARPFV GT KRRTI S HVIQVY R D vlttntdrnrvgap L QP AP V W vwlrqqltrdpqfgelarqlmaglsyrnqpvkltp 802
Cdd:COG3857 649 LEEELEYI GT PESAL S ELAAAL R Q -------------- L EL AP L W ----------------------------------- 679
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 803 asv EAL Y GYQIYT S I S K LE EFYRNQYAY FL K YGLKL R ER DVF EL S A AST G EF FHAVL DGLI K A L RSDQIPL A QA SD QQ L G 882
Cdd:COG3857 680 --- WDV Y KWLLKL S V S R LE TYAACPFQF FL R YGLKL K ER EEY EL D A PDR G TL FHAVL ERFY K E L KEEGLDW A DL SD EE L E 756
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 883 QY LE TVTRQILDQP Q FT IL T SS N R MA YL QRQ L INTVRQIAFAIRNQSKL S AA EP KQT E VL F gnv G K E H GL KA L DFQIDAT 962
Cdd:COG3857 757 EL LE EAVEELAPEL Q NG IL L SS A R YR YL LER L KRLLKRARRWLEEEARR S GF EP VAL E LS F --- G P E G GL PP L ELELPNG 833
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 963 HSVHV RG K IDR L D QIQV a D QS YL G I V DYKS SQH KFD FQEA YYGLA M Q MLT YLDA V L H N eqalvg SDQAAVKL AGALY M H I 1042
Cdd:COG3857 834 RKIRL RG R IDR I D RLES - D GR YL R I I DYKS GSK KFD LDDV YYGLA L Q LPL YLDA A L E N ------ LEGKEAEP AGALY F H L 906
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1043 Q NP T LK P K D iqggfeaa L LKK N K Y KG I LLDDP QL LE HLD selqqgngtskvypfa R KKDGS YSG gra ASLVTNDQL E R LL 1122
Cdd:COG3857 907 K NP K LK A K K -------- P LKK L K M KG L LLDDP EV LE IIP ---------------- L KKDGS FKN --- SKVLSEEEF E E LL 959
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*...
gi 696567187 1123 Q H NSQ L IIA A A E A I F AG EIQL NP I R LN D K t TA L QY S PY L SI MQ FD AM L AE N A YR D L PP 1180
Cdd:COG3857 960 D H VRE L LKE A G E E I L AG DFAI NP Y R TK D R - TA C QY C PY K SI CR FD ES L EG N E YR K L KK 1016
Name
Accession
Description
Interval
E-value
AddB
COG3857
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1180
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 820.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 4 Q F V LG P A KMDHRRTMVAQLVAT L ma K PQDQFFY LVP NHIK F DT E VDV L N RL aqafgqp D L YAQTQV QV F SF T RLAW YLMK 83
Cdd:COG3857 1 R F I LG R A GSGKTTYLLEEIKEE L -- K EGKPIIL LVP EQMT F QA E RAL L K RL ------- G L GGSIRA QV L SF S RLAW RVLQ 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 84 NEAAYQV P R LS A AG ID MLL YR IL QR H A DEL RL F GGEISQT GF VT QLA RE I N EL QTANLQ PED VVQL A AN aqagd L QA KL H 163
Cdd:COG3857 72 ETGGATR P L LS D AG KR MLL RK IL EE H K DEL KV F ARAADKP GF IE QLA EL I T EL KRYGIT PED LEEA A EL ----- L KE KL R 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 164 DLA IV Y KDFVAAT A DK Y LKPA D I L VQ L NAY L RRQD - L H G THV Y VE la GF AQLPA QE QGIVTTM L EQGAD VTI S L M LD hkv 242
Cdd:COG3857 147 DLA LI Y EAYEEKL A GR Y IDSE D L L RL L AEK L EKSE f L E G AEI Y ID -- GF TDFTP QE LELLEAL L KKAKE VTI T L T LD --- 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 243 vdra P ENGT LF YQS G RL Y Y RL YQY A RIRQIP V SQ diyaetp RVA P G L VA L DDFWRGQ P Q aatgy EE PNTNVHLFRTDS R Q 322
Cdd:COG3857 222 ---- P DELD LF SAT G ET Y E RL LEL A KENGVE V EF ------- KKS P E L AH L ERNLFAY P P ----- EE EPEGIEIIEAAN R R 285
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 323 T E LAQ V G R M IR AM V A kkhadp ADD Y H YRD FLIMT R H L D AY QTMLAPT F H E LE IPYF V D LQ R SMAD HPLVELI NA L FDIDA 402
Cdd:COG3857 286 A E VEA V A R E IR RL V R ------ EEG Y R YRD IAVVV R D L E AY APLIERV F A E YG IPYF I D EK R PLSH HPLVELI LS L LELVR 359
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 403 QQYQ Y R DV M R V LKT E LL mpningqpmd R QAY R QAV D LT EN FI L KS G YH G Q RW VQ R edwqyfql TEGDAGVE TD QNA E ISR 482
Cdd:COG3857 360 SNFR Y E DV F R L LKT G LL ---------- R PLS R EEI D RL EN YV L AY G IR G R RW LE R -------- YLEEEEEL TD EEE E DLE 421
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 483 QI N LIHHFVA E T L P P FFKKMRQ A PDGKAAVTL L VN FL TSQ GV TDQ L LA WR d Q A LDRQ D VRA A A E P EQ T W QTFCGM LDE Y V 562
Cdd:COG3857 422 RL N ELRDRLL E P L L P LRERLKK A KTVREWAEA L YE FL EEL GV PEK L EE WR - E A EEAG D LEE A R E H EQ A W NALIEL LDE L V 500
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 563 TI LG A E PFEITD FL AL L QA G F E GASYSQ IP ST LDQV LISESGMVQSQ D H K V VF MV G ATDL V M P D R IMTNN LLSD VDK E N L 642
Cdd:COG3857 501 EV LG D E KLSLEE FL RI L ES G L E ELTFGL IP PS LDQV QVGGLDRARGL D F K A VF VL G LNEG V F P A R PREDG LLSD EER E R L 580
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 643 Q ptlssl DGDHY L NDSAVVQ L GD E SC L N Y L A FLS A RRH L FF S A PL K D DQETD L NW S NYVR R IQRQ F NLR E HT ylgtpd PT 722
Cdd:COG3857 581 N ------ ELGLE L PPTSRER L LE E RF L F Y R A LTR A SER L YL S Y PL A D EEGKA L LP S PLID R LREL F PEL E ER ------ SL 648
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 723 NADARPFV GT KRRTI S HVIQVY R D vlttntdrnrvgap L QP AP V W vwlrqqltrdpqfgelarqlmaglsyrnqpvkltp 802
Cdd:COG3857 649 LEEELEYI GT PESAL S ELAAAL R Q -------------- L EL AP L W ----------------------------------- 679
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 803 asv EAL Y GYQIYT S I S K LE EFYRNQYAY FL K YGLKL R ER DVF EL S A AST G EF FHAVL DGLI K A L RSDQIPL A QA SD QQ L G 882
Cdd:COG3857 680 --- WDV Y KWLLKL S V S R LE TYAACPFQF FL R YGLKL K ER EEY EL D A PDR G TL FHAVL ERFY K E L KEEGLDW A DL SD EE L E 756
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 883 QY LE TVTRQILDQP Q FT IL T SS N R MA YL QRQ L INTVRQIAFAIRNQSKL S AA EP KQT E VL F gnv G K E H GL KA L DFQIDAT 962
Cdd:COG3857 757 EL LE EAVEELAPEL Q NG IL L SS A R YR YL LER L KRLLKRARRWLEEEARR S GF EP VAL E LS F --- G P E G GL PP L ELELPNG 833
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 963 HSVHV RG K IDR L D QIQV a D QS YL G I V DYKS SQH KFD FQEA YYGLA M Q MLT YLDA V L H N eqalvg SDQAAVKL AGALY M H I 1042
Cdd:COG3857 834 RKIRL RG R IDR I D RLES - D GR YL R I I DYKS GSK KFD LDDV YYGLA L Q LPL YLDA A L E N ------ LEGKEAEP AGALY F H L 906
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1043 Q NP T LK P K D iqggfeaa L LKK N K Y KG I LLDDP QL LE HLD selqqgngtskvypfa R KKDGS YSG gra ASLVTNDQL E R LL 1122
Cdd:COG3857 907 K NP K LK A K K -------- P LKK L K M KG L LLDDP EV LE IIP ---------------- L KKDGS FKN --- SKVLSEEEF E E LL 959
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*...
gi 696567187 1123 Q H NSQ L IIA A A E A I F AG EIQL NP I R LN D K t TA L QY S PY L SI MQ FD AM L AE N A YR D L PP 1180
Cdd:COG3857 960 D H VRE L LKE A G E E I L AG DFAI NP Y R TK D R - TA C QY C PY K SI CR FD ES L EG N E YR K L KK 1016
addB_Gpos
TIGR02773
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1197
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 715.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1 M S L Q F VL G PAKMDHRRTMVAQLVATLMAK P Q - DQFFY LVP NHIK F DT E VDV LN rlaqafg QPD L YAQTQV QV F SF T RLAW 79
Cdd:TIGR02773 1 M G L R F IY G RSGTGKTTFIINEIKQKIKRN P F g KPIIL LVP DQMT F QM E YAL LN ------- DIE L NGMLRA QV L SF S RLAW 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 80 YLMKNEAAYQVPR L SAA G ID ML LYRILQR H A DEL RLFGGEISQT GF VT QL ARE I N E LQTANLQ PED VVQL A ANAQA - GD L 158
Cdd:TIGR02773 74 RVLQETGGLTRTF L TST G KQ ML IRKLIEE H K DEL KVYQKASRKK GF TA QL SEM I T E FKRYEVT PED LRRM A ESITD s EY L 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 159 QA KL H DL A I V Y KD F VAAT AD K YL KPA D I L VQ L NAYLRR - Q D LH G THV Y VE la GF AQLPA QE QGIVTTMLEQGAD VT I SL M 237
Cdd:TIGR02773 154 KE KL E DL S I I Y QQ F EERL AD Q YL DSE D Y L TL L AEKIPQ s E D IK G AEI Y ID -- GF HSFTP QE YSVIEALMKKAKK VT V SL T 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 238 LD h K VVD R A P ENGT LF YQSGRL YYRL Y Q Y A RIRQ I P V SQD I YAE T -- P RVAPG L VA L DDFWRGQ P qa A TG Y E E PNTNVHL 315
Cdd:TIGR02773 232 LD - K PSK R E P DELS LF RATSKT YYRL K Q L A KELG I D V EEP I FLN T er P TKNKE L AH L EKQFDAR P -- A IA Y A E KQESLSI 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 316 F RTDS R QT E LAQ V G R M I RAM V AK K H adpadd Y H Y R D FL I M TR HLDA Y QTMLAPT F HEL EIPYF V D LQ RSM AD HPL V E L I N 395
Cdd:TIGR02773 309 F QANN R RA E VEG V A R E I LRL V RD K G ------ Y R Y K D IA I L TR DPED Y KDLVKAV F SDY EIPYF I D KK RSM LN HPL I E F I R 382
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 396 ALF D IDAQQYQ Y RD V M R V LKT E LL m PNI N GQPM D R qay R QAV D LT EN FI L KS G YH G Q - RW VQREDW QY FQLT - EG D AGVE 473
Cdd:TIGR02773 383 SSL D VIQGNWR Y EA V F R Y LKT G LL - FPL N EPFI D V --- R ELI D QL EN YV L AY G IK G K k RW WKEDWF QY RRFR g LD D DFAQ 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 474 TD QNA E ISRQI N LIHHFVAET L PP F F K K M RQ A PDG K AAVTL L VN FL TSQGVT D Q L LAW R DQ A L D RQDVRA A A E P EQ T W QT 553
Cdd:TIGR02773 459 TD EEI E MQEML N DTRDWIVPP L FT F E K R M KK A KTV K EFAEA L YE FL EELDLP D K L EKE R QR A E D DGRIEE A R E H EQ A W DA 538
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 554 FCGM LDE Y V TI LG A E PFEITD F LALLQA G F E GASY S Q IP ST LDQV LISESGMVQSQDH K VV F MV GA T D L V M P D R IMT N NL 633
Cdd:TIGR02773 539 VIQL LDE F V EV LG N E EMDLNL F QEVIDI G L E QLEF S L IP PA LDQV FVGTMDRSKMYNT K CI F LL GA N D G V L P A R PKE N GI 618
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 634 LSD V D K E N L QPTLSS L D gdhyln DSAVVQ L G DE SC L N Y L AF L SA RRH L FF S A PL K D DQETD L NW S NYVR R IQRQ F N - L R E 712
Cdd:TIGR02773 619 LSD E D R E L L EQIGVE L S ------ STSREK L L DE QF L V Y T AF T SA SDR L KV S Y PL A D AEGKS L RP S IIIH R LEEL F P k L K E 692
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 713 HTY L GT P DPTN a D ARPF vgtkr RTI S HVIQV y RDV LT TNTDRNRV G A P L qp AP VW VWLRQQLTRDPQFGELARQLMA GL S 792
Cdd:TIGR02773 693 SLL L NE P EQVS - D EEQL ----- SYV S NKLPT - LSE LT SQLRKWKR G Y P I -- SD VW WDVYNWYREEDKWKQGLEYVLS GL F 763
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 793 Y R N QPVK L TPASVEA LYG YQ I YT S I S K LE EFYRNQY A Y F LK YGLKL R ER DVFE L S A AST G EF FH AV L DGLIKA L RSDQIP 872
Cdd:TIGR02773 764 Y D N ETKQ L QESKAKQ LYG ER I QA S V S R LE TYNACPF A H F AQ YGLKL K ER KIYK L E A PDL G QL FH EA L KEISDE L KEEKLD 843
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 873 LAQASDQ Q LGQYLETVTRQILDQP Q FT IL T SSNR MA Y L Q RQ L INT V RQIAFAIRN Q S K L S AAE P KQT E VL FG NVGKE hg L 952
Cdd:TIGR02773 844 WSDLTKE Q CRLFANDAVENLAPKL Q HE IL L SSNR YR Y V Q KK L KRI V TRAVGVLSE Q A K R S GFV P VGL E LG FG FGKNP -- L 921
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 953 KA L DF Q IDATHSVHV RG K IDR L D QIQVA D QS YL G I V DYKSS QHKF D FQ E A YYGLA M QMLTYLD A VL H N EQALV G sdq AAV 1032
Cdd:TIGR02773 922 PP L KL Q LKNGEELEL RG R IDR V D KAEKE D ET YL R I I DYKSS SKGL D LT E V YYGLA L QMLTYLD I VL T N SAKWL G --- NQA 998
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1033 KL AG A LY M HI QN P TLKP K D -- IQGGF E AALL K KN K Y KG I LL D D PQLLEHL D SE L QQ gn G T S KVY P FAR KKDGS Y sg G RAA 1110
Cdd:TIGR02773 999 TP AG V LY F HI HD P MIQA K G dl TEEEI E QEIF K EY K M KG L LL S D QEVVRLM D TT L EE -- G S S NII P ASL KKDGS L -- G SRS 1074
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1111 SLV T NDQL E R L LQ H NSQLIIA A A E A I FA G EIQLN P IRLNDK t T AL QY SPYL S IM QFD AM L A EN A YR D L PPLSAKQV L DLL 1190
Cdd:TIGR02773 1075 KAA T EEEF E L L RK H VRRKFQE A G E N I TD G RVSIE P YKMKKQ - T PC QY CNFS S VC QFD TS L E EN E YR H L EAEKDETI L EWI 1153
....*..
gi 696567187 1191 KTQK GG E 1197
Cdd:TIGR02773 1154 NEEV GG N 1160
PDDEXK_1
pfam12705
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
816-1048
1.51e-19
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 89.52
E-value: 1.51e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 816 S I S K LE EFYRNQYAY FL K Y G L K LRE R dv F EL S A AST G EFF HA V L DGLIKAL R sdqi PLAQASDQQ L GQY LE TVTRQILD Q 895
Cdd:pfam12705 3 S P S R LE TYLTCPLRF FL R Y L L G LRE D -- E EL D A PDL G TLV HA A L ERFYRWG R ---- LPEEDLEEL L QAL LE ELWPELGL Q 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 896 PQFT iltss N R MAY L QRQ L INTVRQIAFAIRNQSKLSAA - E P KQT E VL FG N vgkehglkaldfqidat HS V HVR G K IDR L 974
Cdd:pfam12705 77 SEIL ----- P R LPW L AGR L RRRLERMLRRLAEWLRARRG f R P VAV E LG FG G ----------------- TT V RLV G R IDR V 134
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 696567187 975 D Q iqv ADQS YL G I V DYK SSQHKFDFQ -- EA Y Y GL am Q M L T YL D A VLHN E Q AL V G S dqaavkl AGALY MHIQN P TL K 1048
Cdd:pfam12705 135 D L --- DGEG YL R I I DYK TGSAPPQSE dl DL Y E GL -- Q L L L YL L A LAAG E K AL G G P ------- AGALY LRLDD P LK K 198
Name
Accession
Description
Interval
E-value
AddB
COG3857
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1180
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 820.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 4 Q F V LG P A KMDHRRTMVAQLVAT L ma K PQDQFFY LVP NHIK F DT E VDV L N RL aqafgqp D L YAQTQV QV F SF T RLAW YLMK 83
Cdd:COG3857 1 R F I LG R A GSGKTTYLLEEIKEE L -- K EGKPIIL LVP EQMT F QA E RAL L K RL ------- G L GGSIRA QV L SF S RLAW RVLQ 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 84 NEAAYQV P R LS A AG ID MLL YR IL QR H A DEL RL F GGEISQT GF VT QLA RE I N EL QTANLQ PED VVQL A AN aqagd L QA KL H 163
Cdd:COG3857 72 ETGGATR P L LS D AG KR MLL RK IL EE H K DEL KV F ARAADKP GF IE QLA EL I T EL KRYGIT PED LEEA A EL ----- L KE KL R 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 164 DLA IV Y KDFVAAT A DK Y LKPA D I L VQ L NAY L RRQD - L H G THV Y VE la GF AQLPA QE QGIVTTM L EQGAD VTI S L M LD hkv 242
Cdd:COG3857 147 DLA LI Y EAYEEKL A GR Y IDSE D L L RL L AEK L EKSE f L E G AEI Y ID -- GF TDFTP QE LELLEAL L KKAKE VTI T L T LD --- 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 243 vdra P ENGT LF YQS G RL Y Y RL YQY A RIRQIP V SQ diyaetp RVA P G L VA L DDFWRGQ P Q aatgy EE PNTNVHLFRTDS R Q 322
Cdd:COG3857 222 ---- P DELD LF SAT G ET Y E RL LEL A KENGVE V EF ------- KKS P E L AH L ERNLFAY P P ----- EE EPEGIEIIEAAN R R 285
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 323 T E LAQ V G R M IR AM V A kkhadp ADD Y H YRD FLIMT R H L D AY QTMLAPT F H E LE IPYF V D LQ R SMAD HPLVELI NA L FDIDA 402
Cdd:COG3857 286 A E VEA V A R E IR RL V R ------ EEG Y R YRD IAVVV R D L E AY APLIERV F A E YG IPYF I D EK R PLSH HPLVELI LS L LELVR 359
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 403 QQYQ Y R DV M R V LKT E LL mpningqpmd R QAY R QAV D LT EN FI L KS G YH G Q RW VQ R edwqyfql TEGDAGVE TD QNA E ISR 482
Cdd:COG3857 360 SNFR Y E DV F R L LKT G LL ---------- R PLS R EEI D RL EN YV L AY G IR G R RW LE R -------- YLEEEEEL TD EEE E DLE 421
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 483 QI N LIHHFVA E T L P P FFKKMRQ A PDGKAAVTL L VN FL TSQ GV TDQ L LA WR d Q A LDRQ D VRA A A E P EQ T W QTFCGM LDE Y V 562
Cdd:COG3857 422 RL N ELRDRLL E P L L P LRERLKK A KTVREWAEA L YE FL EEL GV PEK L EE WR - E A EEAG D LEE A R E H EQ A W NALIEL LDE L V 500
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 563 TI LG A E PFEITD FL AL L QA G F E GASYSQ IP ST LDQV LISESGMVQSQ D H K V VF MV G ATDL V M P D R IMTNN LLSD VDK E N L 642
Cdd:COG3857 501 EV LG D E KLSLEE FL RI L ES G L E ELTFGL IP PS LDQV QVGGLDRARGL D F K A VF VL G LNEG V F P A R PREDG LLSD EER E R L 580
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 643 Q ptlssl DGDHY L NDSAVVQ L GD E SC L N Y L A FLS A RRH L FF S A PL K D DQETD L NW S NYVR R IQRQ F NLR E HT ylgtpd PT 722
Cdd:COG3857 581 N ------ ELGLE L PPTSRER L LE E RF L F Y R A LTR A SER L YL S Y PL A D EEGKA L LP S PLID R LREL F PEL E ER ------ SL 648
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 723 NADARPFV GT KRRTI S HVIQVY R D vlttntdrnrvgap L QP AP V W vwlrqqltrdpqfgelarqlmaglsyrnqpvkltp 802
Cdd:COG3857 649 LEEELEYI GT PESAL S ELAAAL R Q -------------- L EL AP L W ----------------------------------- 679
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 803 asv EAL Y GYQIYT S I S K LE EFYRNQYAY FL K YGLKL R ER DVF EL S A AST G EF FHAVL DGLI K A L RSDQIPL A QA SD QQ L G 882
Cdd:COG3857 680 --- WDV Y KWLLKL S V S R LE TYAACPFQF FL R YGLKL K ER EEY EL D A PDR G TL FHAVL ERFY K E L KEEGLDW A DL SD EE L E 756
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 883 QY LE TVTRQILDQP Q FT IL T SS N R MA YL QRQ L INTVRQIAFAIRNQSKL S AA EP KQT E VL F gnv G K E H GL KA L DFQIDAT 962
Cdd:COG3857 757 EL LE EAVEELAPEL Q NG IL L SS A R YR YL LER L KRLLKRARRWLEEEARR S GF EP VAL E LS F --- G P E G GL PP L ELELPNG 833
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 963 HSVHV RG K IDR L D QIQV a D QS YL G I V DYKS SQH KFD FQEA YYGLA M Q MLT YLDA V L H N eqalvg SDQAAVKL AGALY M H I 1042
Cdd:COG3857 834 RKIRL RG R IDR I D RLES - D GR YL R I I DYKS GSK KFD LDDV YYGLA L Q LPL YLDA A L E N ------ LEGKEAEP AGALY F H L 906
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1043 Q NP T LK P K D iqggfeaa L LKK N K Y KG I LLDDP QL LE HLD selqqgngtskvypfa R KKDGS YSG gra ASLVTNDQL E R LL 1122
Cdd:COG3857 907 K NP K LK A K K -------- P LKK L K M KG L LLDDP EV LE IIP ---------------- L KKDGS FKN --- SKVLSEEEF E E LL 959
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*...
gi 696567187 1123 Q H NSQ L IIA A A E A I F AG EIQL NP I R LN D K t TA L QY S PY L SI MQ FD AM L AE N A YR D L PP 1180
Cdd:COG3857 960 D H VRE L LKE A G E E I L AG DFAI NP Y R TK D R - TA C QY C PY K SI CR FD ES L EG N E YR K L KK 1016
addB_Gpos
TIGR02773
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1197
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 715.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1 M S L Q F VL G PAKMDHRRTMVAQLVATLMAK P Q - DQFFY LVP NHIK F DT E VDV LN rlaqafg QPD L YAQTQV QV F SF T RLAW 79
Cdd:TIGR02773 1 M G L R F IY G RSGTGKTTFIINEIKQKIKRN P F g KPIIL LVP DQMT F QM E YAL LN ------- DIE L NGMLRA QV L SF S RLAW 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 80 YLMKNEAAYQVPR L SAA G ID ML LYRILQR H A DEL RLFGGEISQT GF VT QL ARE I N E LQTANLQ PED VVQL A ANAQA - GD L 158
Cdd:TIGR02773 74 RVLQETGGLTRTF L TST G KQ ML IRKLIEE H K DEL KVYQKASRKK GF TA QL SEM I T E FKRYEVT PED LRRM A ESITD s EY L 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 159 QA KL H DL A I V Y KD F VAAT AD K YL KPA D I L VQ L NAYLRR - Q D LH G THV Y VE la GF AQLPA QE QGIVTTMLEQGAD VT I SL M 237
Cdd:TIGR02773 154 KE KL E DL S I I Y QQ F EERL AD Q YL DSE D Y L TL L AEKIPQ s E D IK G AEI Y ID -- GF HSFTP QE YSVIEALMKKAKK VT V SL T 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 238 LD h K VVD R A P ENGT LF YQSGRL YYRL Y Q Y A RIRQ I P V SQD I YAE T -- P RVAPG L VA L DDFWRGQ P qa A TG Y E E PNTNVHL 315
Cdd:TIGR02773 232 LD - K PSK R E P DELS LF RATSKT YYRL K Q L A KELG I D V EEP I FLN T er P TKNKE L AH L EKQFDAR P -- A IA Y A E KQESLSI 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 316 F RTDS R QT E LAQ V G R M I RAM V AK K H adpadd Y H Y R D FL I M TR HLDA Y QTMLAPT F HEL EIPYF V D LQ RSM AD HPL V E L I N 395
Cdd:TIGR02773 309 F QANN R RA E VEG V A R E I LRL V RD K G ------ Y R Y K D IA I L TR DPED Y KDLVKAV F SDY EIPYF I D KK RSM LN HPL I E F I R 382
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 396 ALF D IDAQQYQ Y RD V M R V LKT E LL m PNI N GQPM D R qay R QAV D LT EN FI L KS G YH G Q - RW VQREDW QY FQLT - EG D AGVE 473
Cdd:TIGR02773 383 SSL D VIQGNWR Y EA V F R Y LKT G LL - FPL N EPFI D V --- R ELI D QL EN YV L AY G IK G K k RW WKEDWF QY RRFR g LD D DFAQ 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 474 TD QNA E ISRQI N LIHHFVAET L PP F F K K M RQ A PDG K AAVTL L VN FL TSQGVT D Q L LAW R DQ A L D RQDVRA A A E P EQ T W QT 553
Cdd:TIGR02773 459 TD EEI E MQEML N DTRDWIVPP L FT F E K R M KK A KTV K EFAEA L YE FL EELDLP D K L EKE R QR A E D DGRIEE A R E H EQ A W DA 538
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 554 FCGM LDE Y V TI LG A E PFEITD F LALLQA G F E GASY S Q IP ST LDQV LISESGMVQSQDH K VV F MV GA T D L V M P D R IMT N NL 633
Cdd:TIGR02773 539 VIQL LDE F V EV LG N E EMDLNL F QEVIDI G L E QLEF S L IP PA LDQV FVGTMDRSKMYNT K CI F LL GA N D G V L P A R PKE N GI 618
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 634 LSD V D K E N L QPTLSS L D gdhyln DSAVVQ L G DE SC L N Y L AF L SA RRH L FF S A PL K D DQETD L NW S NYVR R IQRQ F N - L R E 712
Cdd:TIGR02773 619 LSD E D R E L L EQIGVE L S ------ STSREK L L DE QF L V Y T AF T SA SDR L KV S Y PL A D AEGKS L RP S IIIH R LEEL F P k L K E 692
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 713 HTY L GT P DPTN a D ARPF vgtkr RTI S HVIQV y RDV LT TNTDRNRV G A P L qp AP VW VWLRQQLTRDPQFGELARQLMA GL S 792
Cdd:TIGR02773 693 SLL L NE P EQVS - D EEQL ----- SYV S NKLPT - LSE LT SQLRKWKR G Y P I -- SD VW WDVYNWYREEDKWKQGLEYVLS GL F 763
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 793 Y R N QPVK L TPASVEA LYG YQ I YT S I S K LE EFYRNQY A Y F LK YGLKL R ER DVFE L S A AST G EF FH AV L DGLIKA L RSDQIP 872
Cdd:TIGR02773 764 Y D N ETKQ L QESKAKQ LYG ER I QA S V S R LE TYNACPF A H F AQ YGLKL K ER KIYK L E A PDL G QL FH EA L KEISDE L KEEKLD 843
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 873 LAQASDQ Q LGQYLETVTRQILDQP Q FT IL T SSNR MA Y L Q RQ L INT V RQIAFAIRN Q S K L S AAE P KQT E VL FG NVGKE hg L 952
Cdd:TIGR02773 844 WSDLTKE Q CRLFANDAVENLAPKL Q HE IL L SSNR YR Y V Q KK L KRI V TRAVGVLSE Q A K R S GFV P VGL E LG FG FGKNP -- L 921
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 953 KA L DF Q IDATHSVHV RG K IDR L D QIQVA D QS YL G I V DYKSS QHKF D FQ E A YYGLA M QMLTYLD A VL H N EQALV G sdq AAV 1032
Cdd:TIGR02773 922 PP L KL Q LKNGEELEL RG R IDR V D KAEKE D ET YL R I I DYKSS SKGL D LT E V YYGLA L QMLTYLD I VL T N SAKWL G --- NQA 998
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1033 KL AG A LY M HI QN P TLKP K D -- IQGGF E AALL K KN K Y KG I LL D D PQLLEHL D SE L QQ gn G T S KVY P FAR KKDGS Y sg G RAA 1110
Cdd:TIGR02773 999 TP AG V LY F HI HD P MIQA K G dl TEEEI E QEIF K EY K M KG L LL S D QEVVRLM D TT L EE -- G S S NII P ASL KKDGS L -- G SRS 1074
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1111 SLV T NDQL E R L LQ H NSQLIIA A A E A I FA G EIQLN P IRLNDK t T AL QY SPYL S IM QFD AM L A EN A YR D L PPLSAKQV L DLL 1190
Cdd:TIGR02773 1075 KAA T EEEF E L L RK H VRRKFQE A G E N I TD G RVSIE P YKMKKQ - T PC QY CNFS S VC QFD TS L E EN E YR H L EAEKDETI L EWI 1153
....*..
gi 696567187 1191 KTQK GG E 1197
Cdd:TIGR02773 1154 NEEV GG N 1160
rexB_recomb
TIGR02774
ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in ...
13-1185
2.26e-79
ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RecAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. The partner may be designated AddB, as in Bacillus and in alphaproteobacteria, or RexB as in Streptococcus and Lactococcus. Note, however, that RexB proteins lack an N-terminal GxxGxGK[ST] ATP-binding motif found in Bacillus subtilis and related species, and this difference may be important; this model represents specifically RexB proteins as found in Streptococcus and Lactococcus. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274291 [Multi-domain]
Cd Length: 1076
Bit Score: 283.65
E-value: 2.26e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 13 D H R RTMVAQ LV -- A TLM A KPQDQF FY LV PN HIK F DT E VD VL NR L A Q A fgqpdly A QTQVQ V FS F TRL A W Y LMK N EAAYQV 90
Cdd:TIGR02774 6 D I R TSLTEI LV ne A EEA A AAGKRV FY IA PN SLS F EK E RA VL EY L P Q Q ------- A SFSIT V TR F AQM A R Y FVL N DLPAKT 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 91 P r L SAA G ID M LL YR I L QRHADE - L RLF G GEISQTG F VT QL AREIN ELQ TAN L QPE D VVQ L AANAQAG DL Q A KL hdl AI V Y 169
Cdd:TIGR02774 79 T - L DDI G LA M IF YR A L AQLEPG d L KVY G RLKQDPQ F IQ QL VELYK ELQ KSQ L SIL D LEN L TSPDKRE DL L A IF --- EK V T 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 170 KDFVAATADKYL K P A DILVQLNAYLRRQ DL HG T HVYVE la GF AQLP A Q E QGI V TTMLEQ G ADVT I SLMLDH K VVDRAPEN 249
Cdd:TIGR02774 155 AYLNQGQYAQQS K L A HFIEAIESGKLDS DL KN T VLVID -- GF TRFS A E E EAL V SLLHGK G VEII I GAYASQ K AYKSSFSE 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 250 G T L FYQ S GRLYYR L Y Q YARIR ----- QIPV S Q D IYAETP R V apg L V A LD DF WRGQPQAA tgy EEPNT N VHLFRTDSRQT E 324
Cdd:TIGR02774 233 G N L YQA S VKFLHD L A Q KYQTK aefis STHE S K D SFDKLS R L --- L E A SH DF SELALDLD --- DKDKD N LTIWSCLTQKE E 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 325 LAQ V G R M IR AMVA kkhadpa DD Y H Y R D F L IMTRHL D A YQ TM L APT F HELE IP YFVDLQRS MA D HPLV EL I NA L FD I da QQ 404
Cdd:TIGR02774 307 VEH V A R S IR QKLY ------- EG Y R Y K D I L VLLGDV D S YQ LQ L GKI F DQYD IP FYLGKAEP MA H HPLV QF I ES L ER I -- KR 377
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 405 Y QY R -- DV MRV LKT E L L m PNINGQPM D R - QA Y RQAV D L tenfilksgyhgqrwvqredwqyfqlt E G DAGVETDQNAEIS 481
Cdd:TIGR02774 378 Y RF R ae DV LNL LKT G L Y - GDFSQSDI D A f EQ Y IRYA D I --------------------------- K G LPKFQKTFTKNHH 429
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 482 RQIN L ----- IHHFVAET L PPF FK KMR Q ap D G KAAVTLLVN FL TSQGV T DQ L -- LA WRDQALDRQ dvraaa EP E QT W Q TF 554
Cdd:TIGR02774 430 GKFD L drlnv LRQRILAP L EEL FK SRK Q -- L G EKLLNKFSV FL KEIAL T KN L qd LA TTLSEVEQE ------ KQ E EV W K TF 501
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 555 CGM L DEYV TI L G A E PFEIT DFLALL QA G FEGAS Y SQI P S T L D Q V LISESGMVQSQDHKV V FMV G A T DLVM P DRIMTNN LL 634
Cdd:TIGR02774 502 TDI L EQFA TI F G Q E KLSLD DFLALL HS G MSLSQ Y RTV P A T V D V V TVKSYDLIEPHTAPF V YAI G L T QSNF P KISQNSS LL 581
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 635 S D VDKE NL QP tl SSLD G D H YLND S A vvqlg DESCL N YLAF LS ---- A RRH L FF SAP - L KDDQ E TDL nw S N Y V --- RRIQR 706
Cdd:TIGR02774 582 T D EERQ NL ND -- ATEE G G H FDIA S Q ----- ENLKK N HYTM LS lfns A TKE L VL SAP q L FNES E DKE -- S P Y L qel IDFGV 652
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 707 QFNLREHTY LG T pdp TNA D arpf V G TKRRTI S H V IQVYRDVLTTN T D rnrvgapl Q PAPV W V ---- W LR QQ L TR dpqfge 782
Cdd:TIGR02774 653 PLREKGMNS LG E --- DKE D ---- I G NYKALL S R V VAYNQQGEMEM T K -------- Q DLTF W S vlvr Y LR KK L DQ ------ 711
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 783 la RQ L - MAGLSYRNQPVK L TPASVE ALY -- GYQIYT S I S K L EE FY R NQY A YFL K Y G L K L R E RDVFELS A AST G EFF H AVL 859
Cdd:TIGR02774 712 -- QG L e IPTITDSLSTKT L SKDVLQ ALY pa DQPLKL S A S A L TT FY N NQY S YFL R Y V L G L E E EESIHPD A RHH G NYL H RIF 789
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 860 DG L I K alrsdqipla QASDQQLG Q Y L ETVTRQILDQPQ F TI L TSSNRM A - Y LQRQ L INTV R QI A FAI R NQ S KLSAA ep K Q 938
Cdd:TIGR02774 790 ER L M K ---------- LPGEESFD Q K L NQAINETSQERE F EA L YQEDAE A r Y TLEI L LDIA R ST A PIL R HN S AIQVI -- K E 857
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 939 T E VLF G NVGKE hglkald F QID ATH S VH VRG K IDR L D QI qv A D QSY LG I VDYKSS QHK FD FQEA Y Y GL AM Q ML TYL D A V l 1018
Cdd:TIGR02774 858 E E NFG G KDNFQ ------- L QID NGR S IF VRG I IDR I D RL -- S D GGS LG V VDYKSS ATQ FD IPHF Y N GL SP Q LP TYL A A L - 927
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1019 h NEQ A LVGSD Q aav KLA GA L Y M H I Q N P TLKPKDIQG -- GFEAALL K KN KY K G I llddpq LL E HLD S E L QQ G NGTS K vypf 1096
Cdd:TIGR02774 928 - KRI A PHEGE Q --- PIF GA M Y L H M Q E P VQDLMAVKN ld DAVVEAS K AL KY Q G L ------ FS E KEK S H L AE G YNKN K ---- 993
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 1097 arkkdgsysggra A S L VTNDQ L ER LL QH N SQ L IIA AAE A I FA G EIQL NP IRLNDKTTALQ ys PYLS I MQ F D A MLAENAY R 1176
Cdd:TIGR02774 994 ------------- A N L YSDEE L QL LL DY N KY L YKK AAE T I LS G RFAI NP YTEDGRSVQGD -- QLKA I TG F E A DRHMGQA R 1058
....*....
gi 696567187 1177 D L PP L S AK Q 1185
Cdd:TIGR02774 1059 R L EK L P AK E 1067
PDDEXK_1
pfam12705
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
816-1048
1.51e-19
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 89.52
E-value: 1.51e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 816 S I S K LE EFYRNQYAY FL K Y G L K LRE R dv F EL S A AST G EFF HA V L DGLIKAL R sdqi PLAQASDQQ L GQY LE TVTRQILD Q 895
Cdd:pfam12705 3 S P S R LE TYLTCPLRF FL R Y L L G LRE D -- E EL D A PDL G TLV HA A L ERFYRWG R ---- LPEEDLEEL L QAL LE ELWPELGL Q 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 896 PQFT iltss N R MAY L QRQ L INTVRQIAFAIRNQSKLSAA - E P KQT E VL FG N vgkehglkaldfqidat HS V HVR G K IDR L 974
Cdd:pfam12705 77 SEIL ----- P R LPW L AGR L RRRLERMLRRLAEWLRARRG f R P VAV E LG FG G ----------------- TT V RLV G R IDR V 134
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 696567187 975 D Q iqv ADQS YL G I V DYK SSQHKFDFQ -- EA Y Y GL am Q M L T YL D A VLHN E Q AL V G S dqaavkl AGALY MHIQN P TL K 1048
Cdd:pfam12705 135 D L --- DGEG YL R I I DYK TGSAPPQSE dl DL Y E GL -- Q L L L YL L A LAAG E K AL G G P ------- AGALY LRLDD P LK K 198
Slr0479
COG2887
RecB family exonuclease [Replication, recombination and repair];
816-1060
3.72e-14
RecB family exonuclease [Replication, recombination and repair];
Pssm-ID: 442133 [Multi-domain]
Cd Length: 248
Bit Score: 73.53
E-value: 3.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 816 S I S KL E EFY R NQYA Y FLK Y G L K LR ERDVFELS AA ST G EFF HAVL DGLI K A lrsdqi P LAQASDQQ L GQY LE TVTRQILDQ 895
Cdd:COG2887 4 S P S RI E TLL R CPLR Y YAR Y I L G LR DPLEPPPD AA DR G TLV HAVL ERFY K L ------ P ADELPAEE L LAL LE EAWAELGFE 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 896 PQFT iltssn RMAY L Q R qlint VRQIAF A - IRNQSKLSAA EP KQT EV lfgnvgkehglkal D F QIDATHS V HV RG K IDR L 974
Cdd:COG2887 78 DPWA ------ AALW L E R ----- AERLLE A f LEWERAPAGL EP VAV EV -------------- E F ELELPGG V RL RG R IDR I 132
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696567187 975 D qiq VADQSY L GI VDYK SSQHKFDFQ EA yy G LAM Q MLT Y ldavlhne QALV -- G SDQAAVKL A GAL Y MHIQNPTLKPKDI 1052
Cdd:COG2887 133 D --- RLPDGR L VV VDYK TGKAPSTKD EA -- G EDP Q LAL Y -------- ALAL er G FEGLVPAG A RLV Y LGDLGKKKVLDPL 199
....*...
gi 696567187 1053 QGGF E A A L 1060
Cdd:COG2887 200 EEEL E E A E 207
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01