|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05632 |
PRK05632 |
phosphate acetyltransferase; Reviewed |
1-714 |
0e+00 |
|
phosphate acetyltransferase; Reviewed
Pssm-ID: 235537 [Multi-domain] Cd Length: 684 Bit Score: 1250.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 1 MARTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQPrpgetgterstaviraaaninppePFALSYAENMITS 80
Cdd:PRK05632 1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLAS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 81 SNTDILLEEIVARFEEHvkTSGAEVVVIEGLVPTDKQPFANKLNYDVAKALDADMVFVTHPGNDSSQKLKERIELACSNF 160
Cdd:PRK05632 57 GQLDELLEEIVARYHAL--AKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSF 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 161 GGVNNPRIVGCVINKVGAPVDEHGVTRPDLTEMFEAHHHgadtgHNLEVLQVFGKSPLRILGCIPWNTQLIAPRAKDLAK 240
Cdd:PRK05632 135 GGAKNANILGVIINKLNAPVDEQGRTRPDLSEIFDDSSK-----ANVDPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAK 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 241 HLAAKIINKGELESRRLQTVTFCARSIHNMIEHFRPGSLLVTSGDRSDVIVSACLSAMNGVKLGALLLTGNYHPEPQVMA 320
Cdd:PRK05632 210 HLGATVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAK 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 321 LCQQAMATGLPIMITGTNTWQTAVSLQNFNVDIPEDDRERIELVQDYVAGHIDKH-WIESLSAKSTRSRRLSPPAFRYQL 399
Cdd:PRK05632 290 LCEGAFETGLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQL 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 400 TELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDRVEIIDPVAVRERYVARLVELR 479
Cdd:PRK05632 370 TERARAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELR 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 480 KNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLVYGDCA 559
Cdd:PRK05632 450 KHKGMTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCA 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 560 INPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAIMENVA 639
Cdd:PRK05632 530 VNPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVA 609
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 752543140 640 KSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQAA 714
Cdd:PRK05632 610 RSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
|
|
| PtaN |
COG0857 |
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; |
1-717 |
0e+00 |
|
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
Pssm-ID: 440618 [Multi-domain] Cd Length: 697 Bit Score: 823.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 1 MARTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQPRPGETGTERSTAVIRAAANI----NPPEPFALSYAEN 76
Cdd:COG0857 1 MMKSIYIASTEPGSGKTSVALGLARALQRKGLRVGYFKPIGQSLVGGGERDEDVELIREHLGLdlpyEDASPVTLDEVET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 77 MITSSNTDILLEEIVARFEEHvkTSGAEVVVIEGLVPTDKQ-PFANKLNYDVAKALDADMVFVTHPGNDSSQKLKERIEL 155
Cdd:COG0857 81 LLAEGDPDELLERIVERYEAL--AAECDVVLVEGSDPTGVGsPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 156 ACSNFGGvNNPRIVGCVINKVGAPVDEHGVTrpdltemfeahhhgadtghnlEVLQVFGKSPLRILGCIPWNTQLIAPRA 235
Cdd:COG0857 159 AADEFRG-EGARVLGVIINRVPPEKLEEVRE---------------------ALRPFLEGSGIPVLGVIPENPELAAPTV 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 236 KDLAKHLAAKIINKGELESRRLQTVTFCARSIHNMIEHFRPGSLLVTSGDRSDVIVSACLSAMNGV-KLGALLLTGNYHP 314
Cdd:COG0857 217 RDLAEALGAEVLNGGELLDRRVESVVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGTpSIAGLILTGGLPP 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 315 EPQVMALCQQAMATgLPIMITGTNTWQTAVSLQNFNVDIPEDDRERIELVQDYVAGHIDKHWIESLSakSTRSRRLSPPA 394
Cdd:COG0857 297 DPAVLRLAEGLGQT-LPILSVELDTYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSRL--GLPRSRLSPPA 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 395 FRYQLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDRVEIIDPVAVRERYVAR 474
Cdd:COG0857 374 FFYYLLERAARAAKRIVLPEGGEDRRILAAAICLLRRIAACVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAA 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 475 LVELRKNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLV 554
Cdd:COG0857 454 EVYLRRRKKKGVTVAAAQLEDDVVLYTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVV 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 555 YGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAI 634
Cdd:COG0857 534 VGDCACAPNPPPEELALAAIISSSSAAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAA 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 635 MENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQAA 714
Cdd:COG0857 614 AADVVVAKAKPSPVAGAAAAFVFPFLDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQ 693
|
...
gi 752543140 715 QAE 717
Cdd:COG0857 694 QQA 696
|
|
| pta |
TIGR00651 |
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ... |
410-709 |
2.92e-169 |
|
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]
Pssm-ID: 273196 [Multi-domain] Cd Length: 303 Bit Score: 487.33 E-value: 2.92e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 410 VVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTdRVEIIDPV--AVRERYVARLVELRKNKGMTEV 487
Cdd:TIGR00651 1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKAAGCNLDLG-HVVIIDPDvsPDRESYAERYVELRKHKGMTEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 488 VAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLVYGDCAINPDPTAE 567
Cdd:TIGR00651 80 QARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 568 QLAEIAIQSADSAAAFG-IEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAIMENVAKSKAPNS 646
Cdd:TIGR00651 160 QLAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPNS 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 752543140 647 PVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALT 709
Cdd:TIGR00651 240 PVAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAIT 302
|
|
| PTA_PTB |
pfam01515 |
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ... |
395-709 |
5.51e-156 |
|
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.
Pssm-ID: 396207 [Multi-domain] Cd Length: 318 Bit Score: 454.08 E-value: 5.51e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 395 FRYQLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLtDRVEIIDPVAVR--ERYV 472
Cdd:pfam01515 1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDL-DGIEIVDPETSPrlEEYA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 473 ARLVELRKNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQV 552
Cdd:pfam01515 80 DFYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 553 LVYGDCAINPDPTAEQLAEIAIQSADSAAAFG-IEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYD 631
Cdd:pfam01515 160 LFFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFD 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 752543140 632 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALT 709
Cdd:pfam01515 240 AALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAIT 317
|
|
| DTBS |
cd03109 |
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ... |
3-193 |
4.45e-26 |
|
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.
Pssm-ID: 349763 [Multi-domain] Cd Length: 189 Bit Score: 105.73 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 3 RTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQprpGETGTERSTAV-IRAAANINPP----EPFALSYAenm 77
Cdd:cd03109 1 KTLFVTGTDTDVGKTVVSAGLARALRKKGIKVGYLKPVQT---GCPGLEDSDAElLRKLAGLLLDleliNPYRFEAP--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 78 iTS-------SNTDILLEEIVARFEEHVKTSgaEVVVIEGLVPTDKQPFANKLNYDVAKALDADMVFVTHPGNDSSQKLK 150
Cdd:cd03109 75 -LSphlaaelEGRDIDLEEIVRALEELAKSY--DVVLVEGAGGLLVPLTEGYLNADLARALGLPVILVARGGLGTINHTL 151
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 752543140 151 ERIELACSnfggvNNPRIVGCVINKVGAPVDEHGVTRPDLTEM 193
Cdd:cd03109 152 LTLEALKS-----RGLDVAGVVLNGIPPEPEAEADNAETLKEL 189
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05632 |
PRK05632 |
phosphate acetyltransferase; Reviewed |
1-714 |
0e+00 |
|
phosphate acetyltransferase; Reviewed
Pssm-ID: 235537 [Multi-domain] Cd Length: 684 Bit Score: 1250.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 1 MARTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQPrpgetgterstaviraaaninppePFALSYAENMITS 80
Cdd:PRK05632 1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLAS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 81 SNTDILLEEIVARFEEHvkTSGAEVVVIEGLVPTDKQPFANKLNYDVAKALDADMVFVTHPGNDSSQKLKERIELACSNF 160
Cdd:PRK05632 57 GQLDELLEEIVARYHAL--AKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSF 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 161 GGVNNPRIVGCVINKVGAPVDEHGVTRPDLTEMFEAHHHgadtgHNLEVLQVFGKSPLRILGCIPWNTQLIAPRAKDLAK 240
Cdd:PRK05632 135 GGAKNANILGVIINKLNAPVDEQGRTRPDLSEIFDDSSK-----ANVDPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAK 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 241 HLAAKIINKGELESRRLQTVTFCARSIHNMIEHFRPGSLLVTSGDRSDVIVSACLSAMNGVKLGALLLTGNYHPEPQVMA 320
Cdd:PRK05632 210 HLGATVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAK 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 321 LCQQAMATGLPIMITGTNTWQTAVSLQNFNVDIPEDDRERIELVQDYVAGHIDKH-WIESLSAKSTRSRRLSPPAFRYQL 399
Cdd:PRK05632 290 LCEGAFETGLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQL 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 400 TELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDRVEIIDPVAVRERYVARLVELR 479
Cdd:PRK05632 370 TERARAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELR 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 480 KNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLVYGDCA 559
Cdd:PRK05632 450 KHKGMTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCA 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 560 INPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAIMENVA 639
Cdd:PRK05632 530 VNPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVA 609
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 752543140 640 KSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQAA 714
Cdd:PRK05632 610 RSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
|
|
| PtaN |
COG0857 |
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; |
1-717 |
0e+00 |
|
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
Pssm-ID: 440618 [Multi-domain] Cd Length: 697 Bit Score: 823.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 1 MARTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQPRPGETGTERSTAVIRAAANI----NPPEPFALSYAEN 76
Cdd:COG0857 1 MMKSIYIASTEPGSGKTSVALGLARALQRKGLRVGYFKPIGQSLVGGGERDEDVELIREHLGLdlpyEDASPVTLDEVET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 77 MITSSNTDILLEEIVARFEEHvkTSGAEVVVIEGLVPTDKQ-PFANKLNYDVAKALDADMVFVTHPGNDSSQKLKERIEL 155
Cdd:COG0857 81 LLAEGDPDELLERIVERYEAL--AAECDVVLVEGSDPTGVGsPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 156 ACSNFGGvNNPRIVGCVINKVGAPVDEHGVTrpdltemfeahhhgadtghnlEVLQVFGKSPLRILGCIPWNTQLIAPRA 235
Cdd:COG0857 159 AADEFRG-EGARVLGVIINRVPPEKLEEVRE---------------------ALRPFLEGSGIPVLGVIPENPELAAPTV 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 236 KDLAKHLAAKIINKGELESRRLQTVTFCARSIHNMIEHFRPGSLLVTSGDRSDVIVSACLSAMNGV-KLGALLLTGNYHP 314
Cdd:COG0857 217 RDLAEALGAEVLNGGELLDRRVESVVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGTpSIAGLILTGGLPP 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 315 EPQVMALCQQAMATgLPIMITGTNTWQTAVSLQNFNVDIPEDDRERIELVQDYVAGHIDKHWIESLSakSTRSRRLSPPA 394
Cdd:COG0857 297 DPAVLRLAEGLGQT-LPILSVELDTYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSRL--GLPRSRLSPPA 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 395 FRYQLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDRVEIIDPVAVRERYVAR 474
Cdd:COG0857 374 FFYYLLERAARAAKRIVLPEGGEDRRILAAAICLLRRIAACVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAA 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 475 LVELRKNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLV 554
Cdd:COG0857 454 EVYLRRRKKKGVTVAAAQLEDDVVLYTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVV 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 555 YGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAI 634
Cdd:COG0857 534 VGDCACAPNPPPEELALAAIISSSSAAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAA 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 635 MENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQAA 714
Cdd:COG0857 614 AADVVVAKAKPSPVAGAAAAFVFPFLDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQ 693
|
...
gi 752543140 715 QAE 717
Cdd:COG0857 694 QQA 696
|
|
| Pta |
COG0280 |
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production ... |
394-712 |
5.73e-172 |
|
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production and conversion];
Pssm-ID: 440049 [Multi-domain] Cd Length: 320 Bit Score: 494.97 E-value: 5.73e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 394 AFRYQLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDrVEIIDPV--AVRERY 471
Cdd:COG0280 1 KFFRPLIERAKAAPKRIVFAEGEDERVLRAAQEALDEGLAEPILVGRPEKIEARAEELGLDLSG-FEIIDPEdsPRYEEY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 472 VARLVELRKNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQ 551
Cdd:COG0280 80 AEAYYELRKRKGVTPEEARELVRDAAYFAAMMVRLGEADGLVKGAVGTTADLLRPVLQIIGLRPGVKRVSHVFLMELPDR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 552 VLVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYD 631
Cdd:COG0280 160 LLFITDTAVNIDPTAEQLADIAINAADTARAFGIEPKVALLSASEFGSPKGPSTDKVREATKMARGQIPDLEVDGELQFD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 632 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGI 711
Cdd:COG0280 240 AALSPEAAKRKGPDSPVAGDANVLVFPDLEAGNILYKLLQRLAGAEAIGPILLGLAKPVHLLSRGDSVRDIVNSIALAAV 319
|
.
gi 752543140 712 Q 712
Cdd:COG0280 320 Q 320
|
|
| pta |
TIGR00651 |
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ... |
410-709 |
2.92e-169 |
|
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]
Pssm-ID: 273196 [Multi-domain] Cd Length: 303 Bit Score: 487.33 E-value: 2.92e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 410 VVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTdRVEIIDPV--AVRERYVARLVELRKNKGMTEV 487
Cdd:TIGR00651 1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKAAGCNLDLG-HVVIIDPDvsPDRESYAERYVELRKHKGMTEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 488 VAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLVYGDCAINPDPTAE 567
Cdd:TIGR00651 80 QARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 568 QLAEIAIQSADSAAAFG-IEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAIMENVAKSKAPNS 646
Cdd:TIGR00651 160 QLAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPNS 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 752543140 647 PVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALT 709
Cdd:TIGR00651 240 PVAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAIT 302
|
|
| PTA_PTB |
pfam01515 |
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ... |
395-709 |
5.51e-156 |
|
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.
Pssm-ID: 396207 [Multi-domain] Cd Length: 318 Bit Score: 454.08 E-value: 5.51e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 395 FRYQLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLtDRVEIIDPVAVR--ERYV 472
Cdd:pfam01515 1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDL-DGIEIVDPETSPrlEEYA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 473 ARLVELRKNKGMTEVVAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQV 552
Cdd:pfam01515 80 DFYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 553 LVYGDCAINPDPTAEQLAEIAIQSADSAAAFG-IEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYD 631
Cdd:pfam01515 160 LFFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFD 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 752543140 632 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALT 709
Cdd:pfam01515 240 AALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAIT 317
|
|
| eutD |
PRK09653 |
phosphotransacetylase; |
398-713 |
7.80e-156 |
|
phosphotransacetylase;
Pssm-ID: 236609 [Multi-domain] Cd Length: 324 Bit Score: 453.92 E-value: 7.80e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 398 QLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLtDRVEIIDPV--AVRERYVARL 475
Cdd:PRK09653 6 SLKEKAKGKKKKIVLPEGEDERVLKAAKRLQKEGLVEPILLGNPEEIRAKAKELGLDL-DGVEIIDPEtyPLLEEFAEAF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 476 VELRKNKGMTEVvAREQLEDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLVY 555
Cdd:PRK09653 85 VELRKGKGTEED-AAELLKDPNYFGTMLVKLGKADGMVSGAIHSTADTLRPALQIIKTKPGVKTVSSVFIMVKGDERYIF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 556 GDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAIM 635
Cdd:PRK09653 164 ADCAVNPNPTAEQLAEIAINSAETAKAFGIDPKVAMLSFSTKGSAKGPEVDKVQEATEIAKELAPDLKIDGELQFDAAFV 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 752543140 636 ENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQA 713
Cdd:PRK09653 244 PEVAAKKAPGSPVAGKANVFVFPSLEAGNIGYKIAQRLGGFEAVGPILQGLNKPVNDLSRGCSVEDIYNLALITAAQA 321
|
|
| PRK07232 |
PRK07232 |
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed |
398-715 |
8.14e-93 |
|
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
Pssm-ID: 235976 [Multi-domain] Cd Length: 752 Bit Score: 305.10 E-value: 8.14e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 398 QLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDR--VEIIDPV--AVRERYVA 473
Cdd:PRK07232 430 PIFAKAKKDPKRVVFAEGEEERVLRAAQEVVDEGLAKPILIGRPEVIEARIKKLGLDLKAGvdFEIVNPEddPRYEEYWQ 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 474 RLVELRKNKGMTEVVAREQLE-DNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQV 552
Cdd:PRK07232 510 YYYELLQRKGVTPEDARRLVRrDRTVIGAMMVARGDADAMICGLTGRYHEHLRPVRQVIGLRPGVHTAAAMNALLLKGGN 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 553 LVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDA 632
Cdd:PRK07232 590 LFIADTYVNEDPTAEELAEIALMAAEEVRRFGIEPRVALLSHSNFGSSDSPSARKMREAVELLRERAPDLEVDGEMHGDA 669
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 633 AIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQ 712
Cdd:PRK07232 670 ALNEEIRKDLYPFSRLKGPANVLVMPNLEAANISYNLLKELGGGVTIGPILLGMAKPVHILTPSATVRRIVNMTALAVVD 749
|
...
gi 752543140 713 AAQ 715
Cdd:PRK07232 750 AQT 752
|
|
| PRK12862 |
PRK12862 |
malic enzyme; Reviewed |
376-716 |
6.38e-71 |
|
malic enzyme; Reviewed
Pssm-ID: 183799 [Multi-domain] Cd Length: 763 Bit Score: 245.95 E-value: 6.38e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 376 WIESLSAKSTRSRRLSPPAFryqltELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVL 455
Cdd:PRK12862 421 YREQLNQFVYHSGLIMKPVF-----AAAKAAPKRVVFAEGEDERVLRAAQVVVDEGLAKPILIGRPAVIEARIERAGLRL 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 456 TDR--VEIIDPvAVRER---YVARLVELRKNKGMTEVVAREQL-EDNVVLGTMMLERNEVDGLVSGAVHTTANTIRPPMQ 529
Cdd:PRK12862 496 RPGvdFEIVNP-EDDPRyrdYWDTYHALMGRKGVTPEMARREVrRRTTLIGAMMVKRGEADAMICGTEGRYERHLEFVLQ 574
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 530 IIKTAPGSSLISSIFFMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVR 609
Cdd:PRK12862 575 VIGKRPGVRVYAAMSLLILPGRTLFLADTHVNEDPTAEELAEITILAAEEVRRFGIEPKVALLSHSNFGSSDSPSARKMR 654
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 610 EATELAKAKRPDLIIDGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSA-ELVSIGPMLQGMRK 688
Cdd:PRK12862 655 EALEILRERAPDLEVDGEMHGDAALDEELRDRIFPDSRLEGEANLLVFPNLDAANIAYNLLKTAAgNGLAVGPILLGAAK 734
|
330 340
....*....|....*....|....*...
gi 752543140 689 PVNDLSRGALVDDIVYTIALTGIQAAQA 716
Cdd:PRK12862 735 PVHILTPSATVRRIVNMTALAVADANAY 762
|
|
| PRK12861 |
PRK12861 |
malic enzyme; Reviewed |
394-713 |
2.75e-50 |
|
malic enzyme; Reviewed
Pssm-ID: 183798 [Multi-domain] Cd Length: 764 Bit Score: 188.17 E-value: 2.75e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 394 AFRYQLTELARQ-----ANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQG--VVLTDRVEIIDPvA 466
Cdd:PRK12861 430 AFMKPLFAAARQlvrdgGKARIVFTEGEDERVLRAVQVIVDEKLARPILVGRPEVLLARIERFGlrLRLGQDVEVTNP-E 508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 467 VRER---YVARLVELRKNKGMTEVVAREQLEDNVVL-GTMMLERNEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISS 542
Cdd:PRK12861 509 YDERfpqYWTTYWELRCRDGISKEMARVEMRRRLTLiGAMMVRLGDADGMICGTVGEYHNHLRFVDEVIGRKPGASTYAA 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 543 IFFMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDL 622
Cdd:PRK12861 589 MNILLLDQRTVALVDTHVNDNPDAEQIAEFTIAAARQMEWLNLTPKVALLSRSNFGSGSAASGVKMRRALEIVREQAPDL 668
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 623 IIDGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSA-ELVSIGPMLQGMRKPVNDLSRGALVDD 701
Cdd:PRK12861 669 EADGEMHGDCALDEGLRARLLPMSPLKGAANLLVCPNVDAGNIAYNLLKTEAgSNVAVGPFLLGVNAPVNILTSSATVRR 748
|
330
....*....|..
gi 752543140 702 IVYTIALTGIQA 713
Cdd:PRK12861 749 IVNMAALTVIEA 760
|
|
| AAA_26 |
pfam13500 |
AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis ... |
3-234 |
1.29e-40 |
|
AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.
Pssm-ID: 433259 [Multi-domain] Cd Length: 198 Bit Score: 147.41 E-value: 1.29e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 3 RTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQPRPGETGTERSTAVIRAAANINPPEPFALSYAENMITSS- 81
Cdd:pfam13500 1 RTLFVTGTDTGVGKTVVSLGLARALKRRGVKVGYWKPVQTGLVEDGDSELVKRLLGLDQSYEDPEPFRLSAPLSPHLAAr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 82 --NTDILLEEIVARFEEhvktsGAEVVVIEGLVPTDKQPFANKLNYDVAKALDADMVFVTHPGNDSSQKLKERIELACSn 159
Cdd:pfam13500 81 qeGVTIDLEKIIYELPA-----DADPVVVEGAGGLLVPINEDLLNADIAANLGLPVILVARGGLGTINHTLLTLEALRQ- 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 752543140 160 fggvNNPRIVGCVINKVGAPVDEHgvtrpdltemfeahhhgadtghnlevlQVFGKSPLRILGCIPWNTQLIAPR 234
Cdd:pfam13500 155 ----RGIPVLGVILNGVPNPENVR---------------------------TIFAFGGVPVLGAVPYLPDLTAPT 198
|
|
| DRTGG |
pfam07085 |
DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated ... |
237-349 |
9.65e-31 |
|
DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated with CBS domains pfam00571, as well as the CbiA domain pfam01656. The function of this domain is unknown. It is named the DRTGG domain after some of the most conserved residues. This domain may be very distantly related to a pair of CBS domains. There are no significant sequence similarities, but its length and association with CBS domains supports this idea (Bateman A, pers. obs.).
Pssm-ID: 429285 [Multi-domain] Cd Length: 105 Bit Score: 116.06 E-value: 9.65e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 237 DLAKHLAAKIINKGELESRRLQTVTFCARSIHNMIEHFRPGSLLVTSGDRSDVIVSACLSamngvKLGALLLTGNYHPEP 316
Cdd:pfam07085 1 DIARILGAEVLNGGDGLLRRVGKVVVGAMSVENMLKYLRPGDLVITPGDREDIQLAALEA-----GIAGLILTGGFEPSP 75
|
90 100 110
....*....|....*....|....*....|...
gi 752543140 317 QVMALCQQAmatGLPIMITGTNTWQTAVSLQNF 349
Cdd:pfam07085 76 EVLKLAEEL---GLPVLSTPYDTFTTASRINRA 105
|
|
| DTBS |
cd03109 |
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ... |
3-193 |
4.45e-26 |
|
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.
Pssm-ID: 349763 [Multi-domain] Cd Length: 189 Bit Score: 105.73 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 3 RTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQprpGETGTERSTAV-IRAAANINPP----EPFALSYAenm 77
Cdd:cd03109 1 KTLFVTGTDTDVGKTVVSAGLARALRKKGIKVGYLKPVQT---GCPGLEDSDAElLRKLAGLLLDleliNPYRFEAP--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 78 iTS-------SNTDILLEEIVARFEEHVKTSgaEVVVIEGLVPTDKQPFANKLNYDVAKALDADMVFVTHPGNDSSQKLK 150
Cdd:cd03109 75 -LSphlaaelEGRDIDLEEIVRALEELAKSY--DVVLVEGAGGLLVPLTEGYLNADLARALGLPVILVARGGLGTINHTL 151
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 752543140 151 ERIELACSnfggvNNPRIVGCVINKVGAPVDEHGVTRPDLTEM 193
Cdd:cd03109 152 LTLEALKS-----RGLDVAGVVLNGIPPEPEAEADNAETLKEL 189
|
|
| PRK05805 |
PRK05805 |
phosphate butyryltransferase; Validated |
429-716 |
1.08e-21 |
|
phosphate butyryltransferase; Validated
Pssm-ID: 180267 Cd Length: 301 Bit Score: 96.32 E-value: 1.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 429 ERGIARPVLLGNPDEIRRVAEQQGVVLTDrVEIIDPVAVRE--RYVARLVelrkNKGMTEVVAREQLEDNVVLGTMMler 506
Cdd:PRK05805 39 ELGIANAILVGDKEKIKEIAKEIDMDLED-FEIIDEKDNRKaaLKAVELV----SSGKADMVMKGLVDTANFLRAVL--- 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 507 NEVDGLVSGavhttantirppmqiiktapgsSLISSIFFMLLP--DQVLVYGDCAINPDPTAEQLAEIAIQSADSAAAFG 584
Cdd:PRK05805 111 NKEIGLRTG----------------------KTMSHVAVFEVPkyDRLLFLTDAAFNIAPDLKEKIDIINNAVTVAHAIG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 585 IE-PRVAMISystgtsgagaDVEKVR-------EATELAKAKR----PDLIIDGPLQYDAAIMENVAKSKAPNSPVAGKA 652
Cdd:PRK05805 169 IEnPKVAPIC----------AVEVVNpkmpatlDAALLSKMSDrgqiKGCIVDGPLALDNALSEEAAKHKGIDGPVAGNA 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 752543140 653 TVFVFPDLNTGNTTYKAVQRSAElVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQAAQA 716
Cdd:PRK05805 239 DILLVPNIEAGNVMYKTLTYFAD-CKNGGLLVGTSAPVVLTSRADSHETKLNSIALAALVAAKL 301
|
|
| PRK07742 |
PRK07742 |
phosphate butyryltransferase; Validated |
395-708 |
7.96e-20 |
|
phosphate butyryltransferase; Validated
Pssm-ID: 236086 Cd Length: 299 Bit Score: 90.54 E-value: 7.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 395 FRYQLTELARQANKRVVLPEGEEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDRVEIIDPVAVREryVAR 474
Cdd:PRK07742 3 LEHLIDQAAGQPKKTVAVAVAEDEEVIEAVAKAIELQLARFRLYGNQEKIMGMLQEHGLQTSEHIEIIHAQSSAE--AAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 475 LVELRKNKGMTEVVAREQLEDNVVLGTMMlerNEVDGLVSGAVhttantirppmqiiktapgsslISSIFFMLLP--DQV 552
Cdd:PRK07742 81 LAVKAVRNGEADVLMKGNVPTANILKAVL---NKEWGLRKGSV----------------------LSHVAVFEVPnyDRL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 553 LVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIE-PRVAMIsystgtsgagADVEKVR---EATELAKA-----KR---P 620
Cdd:PRK07742 136 IFVTDAAMNIAPDLEQKAAIIQNAVEVARAIGIDlPKVAPL----------AAVEVVNpamQATIDAAAltqmnRRgqiK 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 621 DLIIDGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSAElVSIGPMLQGMRKPVNDLSRGALVD 700
Cdd:PRK07742 206 NCVVDGPLALDNAVSQIAAEHKGIVSDVAGKADILLVPTIEAGNVLYKSLVYFAD-AKVGAMIAGAKAPIVLTSRADSAE 284
|
....*...
gi 752543140 701 DIVYTIAL 708
Cdd:PRK07742 285 TKLYSLAL 292
|
|
| PRK08190 |
PRK08190 |
bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated |
410-668 |
2.77e-19 |
|
bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated
Pssm-ID: 236180 [Multi-domain] Cd Length: 466 Bit Score: 91.48 E-value: 2.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 410 VVLPEgeEPRTIKAAAICAERGIARPVLLGNPDEIRRVAEQQGVVLtDRVEIIDpVAVRERYVARLVELrknkgmtevvA 489
Cdd:PRK08190 181 VVHPC--DAESLRGALEAAEAGLIEPVLVGPEAKIRAAAEEAGLDL-SGVRIVD-VPHSHAAAARAVAL----------A 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 490 ReqlednvvlgtmmleRNEVDGLVSGAVHT---------TANTIRppmqiiktapGSSLISSIFFMLLP--DQVLVYGDC 558
Cdd:PRK08190 247 R---------------AGEVEALMKGSLHTdellsavvaRDSGLR----------TERRISHVFAMDVPtyPRPLLITDA 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 559 AINPDPTAEQLAEIaIQSA-DSAAAFGIE-PRVAMISYstgtsgagadVEKVR-------EATELAK-AKRPDL---IID 625
Cdd:PRK08190 302 AINIAPTLEDKRDI-VQNAiDLAHALGVEePKVAILSA----------VETVNpkmpstlDAAALCKmADRGQItggIVD 370
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 752543140 626 GPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYK 668
Cdd:PRK08190 371 GPLAFDNAISAEAARTKGIVSPVAGQADILVVPDLEAGNMLAK 413
|
|
| PRK11890 |
PRK11890 |
phosphate acetyltransferase; Provisional |
423-695 |
3.58e-16 |
|
phosphate acetyltransferase; Provisional
Pssm-ID: 183361 Cd Length: 312 Bit Score: 80.03 E-value: 3.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 423 AAAICAERGIARPVLLGNPDEIRRVAEQQGVVLTDRvEIIDpVAVRERYVARLVELrknkgmtevvAREqlednvvlgtm 502
Cdd:PRK11890 38 GAVEAAQLGLITPILVGPRARIEAVAAECGLDLSGY-EIVD-APHSHAAAAKAVEL----------VRE----------- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 503 mlerNEVDGLVSGAVHTTAntirpPMQIIkTAPGSSL-----ISSIFFMLLP--DQVLVYGDCAINPDPTAEQLAEIAIQ 575
Cdd:PRK11890 95 ----GEAEALMKGSLHTDE-----LMSAV-VARDTGLrterrISHVFVMDVPgyPKPLIITDAAVNIAPTLEDKADIVQN 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 576 SADSAAAFGI-EPRVAMISystgtsgagaDVEKVR-------EATELAK-AKRPDL---IIDGPLQYDAAIMENVAKSKA 643
Cdd:PRK11890 165 AIDLAHALGFdEPRVAILS----------AVETVNpkipstlDAAALCKmADRGQItgaILDGPLAFDNAISPEAARIKG 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 752543140 644 PNSPVAGKATVFVFPDLNTGNTTYKAVQRSAELVSIGPMLqGMRKPVNDLSR 695
Cdd:PRK11890 235 IVSPVAGDADILVVPDLEAGNMLAKQLTFLAGADAAGIVL-GARVPIILTSR 285
|
|
| BioD |
COG0132 |
Dethiobiotin synthetase [Coenzyme transport and metabolism]; Dethiobiotin synthetase is part ... |
11-242 |
8.84e-12 |
|
Dethiobiotin synthetase [Coenzyme transport and metabolism]; Dethiobiotin synthetase is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 439902 [Multi-domain] Cd Length: 222 Bit Score: 65.18 E-value: 8.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 11 GTGVGVTSVSLGVVRAMERHGVNVSFFKPVAqprpgeTGTERS--------TAVIRAAANINPP----EPFALSYAenmi 78
Cdd:COG0132 10 DTDVGKTVVTAALAAALRAAGLRVGYYKPVQ------TGCEETdgglrngdAELLRRLSGLPLSyelvNPYRFEEP---- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 79 TS-------SNTDILLEEIVARFEEHVKTsgAEVVVIEG----LVP-TDKQPFAnklnyDVAKALDADMVFVTHPG---- 142
Cdd:COG0132 80 LSphlaarlEGVPIDLDKILAALRALAAR--YDLVLVEGagglLVPlTEDLTLA-----DLAKALGLPVILVVRARlgti 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752543140 143 ND---SSQKLKERielacsnfgGVNnprIVGCVINkvgapvdehGVTRPDLTEMfeahhhgadtgHNLEVLQVFGKSPLr 219
Cdd:COG0132 153 NHtllTVEALRAR---------GLP---LAGIVLN---------GVPPPDLAER-----------DNLETLERLTGAPV- 199
|
250 260
....*....|....*....|...
gi 752543140 220 iLGCIPWNTQliaPRAKDLAKHL 242
Cdd:COG0132 200 -LGVLPYLAD---LDPEALAAYL 218
|
|
| |
