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Conserved domains on  [gi|966427224|ref|WP_058469720|]
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spermidine/putrescine ABC transporter permease [Legionella jordanis]

Protein Classification

ABC transporter permease( domain architecture ID 10003093)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 8-267 4.99e-88

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


:

Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 263.55  E-value: 4.99e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   8 LTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSLPFTLANYSALLS-PVFLKIFVRSLVIALLTTLSCLILAYPFSYLL 86
Cdd:COG1176   15 LLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICLLLGYPIAYFL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  87 VKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLLPFMVLPIF 164
Cdd:COG1176   95 ARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTEFAVVIGLVYVYLPFMVLPLY 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 165 TNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQFLVLANW 244
Cdd:COG1176  175 AALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSALNW 254

                        250       260
                 ....*....|....*....|...
gi 966427224 245 PQGSATSIILTALLLLLLFIFRR 267
Cdd:COG1176  255 PLAAALAVVLLLIVLLVLLLYLR 277
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 8-267 4.99e-88

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 263.55  E-value: 4.99e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   8 LTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSLPFTLANYSALLS-PVFLKIFVRSLVIALLTTLSCLILAYPFSYLL 86
Cdd:COG1176   15 LLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICLLLGYPIAYFL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  87 VKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLLPFMVLPIF 164
Cdd:COG1176   95 ARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTEFAVVIGLVYVYLPFMVLPLY 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 165 TNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQFLVLANW 244
Cdd:COG1176  175 AALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSALNW 254

                        250       260
                 ....*....|....*....|...
gi 966427224 245 PQGSATSIILTALLLLLLFIFRR 267
Cdd:COG1176  255 PLAAALAVVLLLIVLLVLLLYLR 277
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 4-270 1.67e-79

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 241.52  E-value: 1.67e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   4 KSISLTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSLPFTLANYSALLSPVFLKIFVRSLVIALLTTLSCLILAYPFS 83
Cdd:PRK09497   8 QNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDANFVKMVFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  84 YLLVK--SKQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLLPFMVL 161
Cdd:PRK09497  88 WFLAKlpHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTESAVIIGLVYILLPFMVL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 162 PIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQFLVL 241
Cdd:PRK09497 168 PLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNI 247

                        250       260
                 ....*....|....*....|....*....
gi 966427224 242 ANWPQGSATSIILTALLLLLLFIFRRQNK 270
Cdd:PRK09497 248 RDWPFGAATSITLTIVMGLMLLVYYRASK 276
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 8-254 1.44e-19

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 87.81  E-value: 1.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224    8 LTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLvslpfTLANYSALL-SPVFLKIFVRSLVIALLTTLSCLILAYPFSYLL 86
Cdd:TIGR03262   7 LAGMILALLLFLLLPLLALLTKSVYDSDGDFI-----GLANFAEYFaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   87 VKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVidaplsllYSNFAVITGLIYNLLPFMVLPIF 164
Cdd:TIGR03262  82 TRSriPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSI--------YGFWGIVIGEVFYTFPHALMILV 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  165 TNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQdQFLVLANW 244
Cdd:TIGR03262 154 TALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNVLATDIYK-QVIGQQNF 232

                         250
                  ....*....|
gi 966427224  245 PQGSATSIIL 254
Cdd:TIGR03262 233 PMGAVVGVLL 242
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-254 1.30e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 44.96  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  61 FVRSLVIALLTTLSCLILAYPFSYLLVKSKqqsllilliiipFWTSSLVRTY-SLIAILKAKGVINSILLKFHVIDAPLS 139
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKR------------GKLDRLLRRIiDLLLSLPSLVLGLLLVLLFGVLLGWGI 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 140 LLYSNFAVITGLIYNLLPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIP 219
Cdd:cd06261   69 LPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV 148

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 966427224 220 NVLGGARSILLGNLIQDQFLVLANWPQGSATSIIL 254
Cdd:cd06261  149 SFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVAL 183
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 8-267 4.99e-88

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 263.55  E-value: 4.99e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   8 LTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSLPFTLANYSALLS-PVFLKIFVRSLVIALLTTLSCLILAYPFSYLL 86
Cdd:COG1176   15 LLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICLLLGYPIAYFL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  87 VKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLLPFMVLPIF 164
Cdd:COG1176   95 ARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTEFAVVIGLVYVYLPFMVLPLY 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 165 TNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQFLVLANW 244
Cdd:COG1176  175 AALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSALNW 254

                        250       260
                 ....*....|....*....|...
gi 966427224 245 PQGSATSIILTALLLLLLFIFRR 267
Cdd:COG1176  255 PLAAALAVVLLLIVLLVLLLYLR 277
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 4-270 1.67e-79

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 241.52  E-value: 1.67e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   4 KSISLTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSLPFTLANYSALLSPVFLKIFVRSLVIALLTTLSCLILAYPFS 83
Cdd:PRK09497   8 QNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDANFVKMVFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  84 YLLVK--SKQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLLPFMVL 161
Cdd:PRK09497  88 WFLAKlpHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTESAVIIGLVYILLPFMVL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 162 PIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQFLVL 241
Cdd:PRK09497 168 PLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNI 247

                        250       260
                 ....*....|....*....|....*....
gi 966427224 242 ANWPQGSATSIILTALLLLLLFIFRRQNK 270
Cdd:PRK09497 248 RDWPFGAATSITLTIVMGLMLLVYYRASK 276
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 12-271 2.55e-51

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 170.66  E-value: 2.55e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  12 YAWLMLFCVLPLTLVLLASF------------LSSNNNQLVSLPFTLANYSALLS-PVFLKIFVRSLVIALLTTLSCLIL 78
Cdd:PRK10683  37 YLWLILLFLLPFLIVFKISLaemaraippytdLMEWADGQLSITLNLGNFLQLTDdPLYFDAYLQSLQVAAISTLCCLLI 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  79 AYPFSYLLVKSK--QQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLL 156
Cdd:PRK10683 117 GYPLAWAVAHSKpsTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYL 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 157 PFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQD 236
Cdd:PRK10683 197 PFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ 276

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 966427224 237 QFLVLANWPQGSATSII-LTALLLLLLFIFRRQNKE 271
Cdd:PRK10683 277 EFFNNRDWPVASAVAIImLLLLIVPIMWFHKHQQKS 312
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 1-267 5.16e-23

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 94.79  E-value: 5.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   1 MRNKSISLTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSLPFTLANYSALLS-PVFLKIFVRSLVIALLTTLSCLILA 79
Cdd:COG1177    2 SRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWFLTFPPEGFTLRWYAELFSdPRLLDALLNSLLIALLSTLLATVLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  80 YPFSYLLVKSKqqsllilliiipFWTSSLVRTYSLIAILkAKGVIN--SILLKFHVIDAPLSLlysnFAVITGLIYNLLP 157
Cdd:COG1177   82 TPAALALARYR------------FRGRRLLLALLLLPLV-VPGIVLgvALLLLFSALGLSGGL----WGLILAHVVFTLP 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 158 FMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQ 237
Cdd:COG1177  145 FVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYIYSM 224

                        250       260       270
                 ....*....|....*....|....*....|
gi 966427224 238 fLVLANWPQGSATSIILTALLLLLLFIFRR 267
Cdd:COG1177  225 -IRRGISPEINALSTLLILLSLLLLLLAER 253
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-224 6.14e-20

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 89.06  E-value: 6.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   2 RNKSISLTIIYAWLMLFCVLPLTLVLLASFLSSnnnqlvslpftLANYSALLS-PVFLKIFVRSLVIALLTTLSCLILAY 80
Cdd:COG1178    7 RRPRLLLLLLALLLALLVLLPLLALLLRAFTDG-----------LANFWALLSdPYLWRALGNTLLLALLVTLLSLLLGV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  81 PFSYLLVKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVIDAPLslLYSNFAVITGLIYNLLPF 158
Cdd:COG1178   76 PLAWLLARTdfPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGLEPPD--IYGLGGIILVLVLFNYPY 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966427224 159 MVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGG 224
Cdd:COG1178  154 VYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGG 219
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 8-254 1.44e-19

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 87.81  E-value: 1.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224    8 LTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLvslpfTLANYSALL-SPVFLKIFVRSLVIALLTTLSCLILAYPFSYLL 86
Cdd:TIGR03262   7 LAGMILALLLFLLLPLLALLTKSVYDSDGDFI-----GLANFAEYFaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   87 VKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHVidaplsllYSNFAVITGLIYNLLPFMVLPIF 164
Cdd:TIGR03262  82 TRSriPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSI--------YGFWGIVIGEVFYTFPHALMILV 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  165 TNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQdQFLVLANW 244
Cdd:TIGR03262 154 TALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNVLATDIYK-QVIGQQNF 232

                         250
                  ....*....|
gi 966427224  245 PQGSATSIIL 254
Cdd:TIGR03262 233 PMGAVVGVLL 242
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 15-269 2.86e-18

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 82.36  E-value: 2.86e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  15 LMLFCVLPLTLVLLASFLSSNNnqlvslpFTLANYSALL-SPVFLKIFVRSLVIALLTTLSCLILAYPFSYLLVkskqqs 93
Cdd:PRK15050  35 LAPLVVYPLVRVVLQSLTGEHG-------LGLATYRAVLgSPDFRGALLTTLQIAFASTAGCLVLGVLLALVLA------ 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  94 llilliIIPFWTSSLVR--------------TYSLIAILKAKGVINSILLK-FHVIDAPLSLLYSNFAVITGLIYNLLPF 158
Cdd:PRK15050 102 ------FVPFPGASLVGrfidtfvafpsfliTLAFTFLYGSAGSVNIALQRlFGLEAPPLDFLYSPGGVILAEITFYTPF 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 159 MVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQDQF 238
Cdd:PRK15050 176 VVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVTLPVLIYSKA 255

                        250       260       270
                 ....*....|....*....|....*....|.
gi 966427224 239 LVLANWPQGSATSIILTALLLLLLFIFRRQN 269
Cdd:PRK15050 256 IVDFDYPTACAIAVVNLALSLGLYALYRRVN 286
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 53-207 1.23e-15

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 73.93  E-value: 1.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  53 LSPVFLKIFVRSLVIALLTTLSCLILAYPFSYLLVKSKqqsllilliiipFWTSSLVRT--------------YSLIAIL 118
Cdd:COG4149    1 LSPEDWSALWLSLKVALIATLLLLLLGIPLAWWLARTR------------FRGKGLLEAlvtlplvlpptvlgFYLLLLF 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 119 KAKGVINSILLKFHVIDAPLSllysnF--AVITGLIYNLlPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPN 196
Cdd:COG4149   69 GRNGPLGQLLEELFGISLVFT-----WtgAVLASVVVSL-PLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPL 142

                        170
                 ....*....|.
gi 966427224 197 TASGVIAGCLL 207
Cdd:COG4149  143 AKPGILAGAVL 153
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-270 3.98e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 71.73  E-value: 3.98e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   6 ISLTIIYAWLMLFCVLPLTLVLLASFLSSNNNQlvslpFTLANYSA-LLSPVFLKIFVRSLVIALLTTLSCLILAYPFSY 84
Cdd:COG1178  289 LALALCLLLVLLGLLLPLLALLLWSLTKALDDN-----LTLDNYRFvLLDPSLLRALLNSLLLALLAALLAVLLALLLAY 363

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  85 LLVKSKQ--QSLLILLIIIPFWTSSLVrtyslIAIlkakgvinSILLKFHVIdAPLSLLYSNFAVITGLIYNLLPFMVLP 162
Cdd:COG1178  364 LVRRRRGrlARLLDRLAMLPYAVPGIV-----LGL--------GLLLLFNRP-LPLLLYGTLAILVLAYVVRFLPFALRS 429

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 163 IFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGARSILLGNLIQdQFLVLA 242
Cdd:COG1178  430 LEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIY-QLASSG 508

                        250       260
                 ....*....|....*....|....*...
gi 966427224 243 NWPQGSATSIILTALLLLLLFIFRRQNK 270
Cdd:COG1178  509 RYGEAAALALLLVLVSLLPVLLLERLLG 536
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 5-207 7.19e-12

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 64.00  E-value: 7.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   5 SISLTIIYAWLMLFCVLPLTLVLLASFLSSnnnqlvslpftLANY-SALLSPVFLKIFVRSLVIALLTTLSCLILAYPFS 83
Cdd:COG0555   10 GLTLGLTLLYLSLIVLLPLAALVLKAAGLG-----------WAEFwAVLTSPRVLAALKLSLGTALIAALINLVFGLPLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  84 YLLVKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHvidapLSLLYSNFAVITGLIYNLLPFMVL 161
Cdd:COG0555   79 WVLVRYrfPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLG-----IKVAFTPLGIVLAQTFVSLPFVVR 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 966427224 162 PIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLL 207
Cdd:COG0555  154 TVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFAL 199
COG4132 COG4132
ABC-type uncharacterized transport system, permease component [General function prediction ...
 13-232 2.27e-09

ABC-type uncharacterized transport system, permease component [General function prediction only];


Pssm-ID: 443307 [Multi-domain]  Cd Length: 286  Bit Score: 56.74  E-value: 2.27e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  13 AWLMLFCVLPLTLVLLASFLSSNNNqlvslpFTLANYSALLSPVFLKIFVRSLVIALLTTLSCLILAYPFSYLLVKSKqq 92
Cdd:COG4132   23 LFVLLFLLLPTVWVVIGAFQDDDGG------FTLANYAELTSPFYLQAFWNSIWLSLASALIGAVIGLLLAYALRRGG-- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  93 sllilliiiPFWTSSLVRTYS--------------LIAILKAKGVINSILLKFHVIDAPLSLLYSNFAVITGLIYNLLPF 158
Cdd:COG4132   95 ---------PGWLRRAVLAFSgvasnfagvplafaFIATLGRNGLVTLLLKQLGIDLYDGFNLYSFWGLILVYLYFQIPL 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966427224 159 MVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPntasgviagcllVLLPSmtlfyipnvLGGARSILLGN 232
Cdd:COG4132  166 MVLLLYPALDGLRREWREAAALLGASRWQYWRRVALP------------VLAPS---------LLGTFLLLFAN 218
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
13-272 6.65e-09

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 55.53  E-value: 6.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  13 AWLMLFCVLPLTLVLLASFLSSNnnqLVSLPFT---LANYSALLS-PVFLKIFVRSLVIALLTTLSCLILAYPFSYLLV- 87
Cdd:COG1175   29 LLLLVFVLYPLLYTLYLSFTDWN---LLGPPPEfvgLDNYARLFTdPRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNr 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  88 KSKQQSLLILLIIIPFWTSSLVRTYSLIAIL-KAKGVINSILLKFHVidAPLSLL----YSNFAVITGLIYNLLPFMVLP 162
Cdd:COG1175  106 KLRGRGFFRTLFFLPWVISPVVVALIWKWLFnPDYGLLNALLGALGL--EPINWLgdpsLALPAVIIVTVWKGTGFNMLI 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 163 IFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVLGGA----RSILLGNLIQDQF 238
Cdd:COG1175  184 FLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGgpgnSTTTLVLYIYQTA 263

                        250       260       270
                 ....*....|....*....|....*....|....
gi 966427224 239 LVLANWPQGSATSIILTALLLLLLFIFRRQNKEG 272
Cdd:COG1175  264 FQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 4-273 1.43e-08

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 54.33  E-value: 1.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   4 KSISLTIIYAWLMLFCVLPLTLVLLASF-----LSSNNNQLVSLPFTLANYSALLSPV-FLKIFVRSLVIALLTTLSCLI 77
Cdd:COG0395   13 GRILLYLLLILLALLFLFPLYWMVVTSFkppaeIFSGPPSLLPSEFTLENYRAAFTDGpFGRYLLNSLIVAVVSTVLSLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  78 LAYPFSYLLVKSKqqsllilliiipFWTSSLVRTYSLIailkakgvinSILLKFHVIDAPLSLLYSNF-------AVITG 150
Cdd:COG0395   93 LSSLAAYALARFR------------FRGRKLLFLLILA----------TLMIPGQVLLIPLYLLFRQLgllntywGLILP 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 151 LIYNLLPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIPNVL---GGARS 227
Cdd:COG0395  151 YLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILltsPDLRT 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 966427224 228 ILLG-NLIQDQFLVlaNWPQGSATSIILTALLLLLLFIFRRQNKEGL 273
Cdd:COG0395  231 LPVGlASFQGQYGT--DWGLLMAAAVIATLPVLILFLFLQRYFVRGL 275
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 156-213 1.67e-08

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 53.83  E-value: 1.67e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 966427224 156 LPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSM 213
Cdd:PRK09500 139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSL 196
modB PRK09421
molybdate ABC transporter permease subunit;
156-228 3.24e-07

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 49.92  E-value: 3.24e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966427224 156 LPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSM-----TLFYIPNVLGGARSI 228
Cdd:PRK09421 104 FPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLgefgaTITFVSNIPGETQTI 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-254 1.30e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 44.96  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  61 FVRSLVIALLTTLSCLILAYPFSYLLVKSKqqsllilliiipFWTSSLVRTY-SLIAILKAKGVINSILLKFHVIDAPLS 139
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKR------------GKLDRLLRRIiDLLLSLPSLVLGLLLVLLFGVLLGWGI 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 140 LLYSNFAVITGLIYNLLPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLFYIP 219
Cdd:cd06261   69 LPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV 148

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 966427224 220 NVLGGARSILLGNLIQDQFLVLANWPQGSATSIIL 254
Cdd:cd06261  149 SFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVAL 183
cysT CHL00187
sulfate transport protein; Provisional
 1-207 3.82e-05

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 43.85  E-value: 3.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   1 MRNKSISLTIIYAWLMLFCVLPLTLVLLAsFLSSNNNQLVSLPFTLAnysalLSPVFLKIFVRSLVIALLTTLSCLILAY 80
Cdd:CHL00187   3 DFNFSLKFSSIYIISLSYIIFLLVLPILA-LLIKASQQPWSDFLQKA-----TEPIALSAYSLTLSMALIAALINGFFGL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  81 PFSYLLVKS--KQQSLLILLIIIPFWTSSLVRTYSLIAILKAKGVINSILLKFHvidapLSLLYSNFAVITGLIYNLLPF 158
Cdd:CHL00187  77 LIAWVLVRYnfPGKRLLDAAVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLG-----IQIVFTKLGVLLAMIFVSFPF 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 966427224 159 MVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLPNTASGVIAGCLL 207
Cdd:CHL00187 152 VVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLAL 200
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 2-195 1.07e-04

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 42.83  E-value: 1.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224   2 RNKSISLTIIYAWLMLFCVLPLTLVLLASFLSSNNNQLVSL---PFTLANYSALLSPV-FLKIFVRSLVIALLTTLSCLI 77
Cdd:COG3833   12 RLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLipeNFTLENYKKLFTETpFLRWFLNSLIVAVVTAIISVF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224  78 L----AYPFSYLLVKSKQQSLLILLIIIPFWTsslvrTYSLIAILkakgvinSILLKFHVIDAPLSLLysnfavitgLIY 153
Cdd:COG3833   92 LaalaAYAFSRFRFKGRKAGLLALLLLQMFPA-----FLALVALY-------LLLSALGLLNTLLGLI---------LVY 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 966427224 154 --NLLPFMVLPIFTNMERFDFRLIEAARDLGASKWAIFFRVFLP 195
Cdd:COG3833  151 lgGAIPFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFFRIILP 194
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
102-216 7.06e-03

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 37.04  E-value: 7.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966427224 102 PFWTSSLVRTYSLIAILKAKGVINSILLKFHVidaplSLLYSNFAVITGLIYNLLPFMVLPIFTNMERFDFRLIEAARDL 181
Cdd:PRK10971 103 PFALPTAVAGLTLASLFSVNGWYGEWLAKFDI-----KVTYTWLGIAVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETL 177

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 966427224 182 GASKWAIFFRVFLPNTASGVIAGCLLVLLPSMTLF 216
Cdd:PRK10971 178 GATRWQSFRKVVLPELSPALLAGVALSFTRSLGEF 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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