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Conserved domains on  [gi|1468626409|ref|WP_117502518|]
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MULTISPECIES: carbohydrate ABC transporter permease [Bifidobacterium]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-294 1.50e-83

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 252.71  E-value: 1.50e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  18 AKPDKIRRDHKVNWWLTAVVTVLSLTVLVPLYFAVVTALKTPGEAGTFS---LPTTWEWHNFADAWNKVNYPKAALNSAI 94
Cdd:COG0395     2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpslLPSEFTLENYRAAFTDGPFGRYLLNSLI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  95 ITVCAVVLTLLTNTFVAYAVARnMDKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHL-DNQLGLIILYTILGIGTNL 173
Cdd:COG0395    82 VAVVSTVLSLLLSSLAAYALAR-FRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLlNTYWGLILPYLAFGLPFGI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 174 FIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTIPLAQYVFQS 253
Cdd:COG0395   161 FLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQG 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1468626409 254 QFTSNYPMAFASYLMAMAPVLIVYIFAQKWVVGGVMRGAVK 294
Cdd:COG0395   241 QYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-294 1.50e-83

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 252.71  E-value: 1.50e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  18 AKPDKIRRDHKVNWWLTAVVTVLSLTVLVPLYFAVVTALKTPGEAGTFS---LPTTWEWHNFADAWNKVNYPKAALNSAI 94
Cdd:COG0395     2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpslLPSEFTLENYRAAFTDGPFGRYLLNSLI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  95 ITVCAVVLTLLTNTFVAYAVARnMDKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHL-DNQLGLIILYTILGIGTNL 173
Cdd:COG0395    82 VAVVSTVLSLLLSSLAAYALAR-FRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLlNTYWGLILPYLAFGLPFGI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 174 FIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTIPLAQYVFQS 253
Cdd:COG0395   161 FLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQG 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1468626409 254 QFTSNYPMAFASYLMAMAPVLIVYIFAQKWVVGGVMRGAVK 294
Cdd:COG0395   241 QYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
ABC_arch_GlcU NF040932
glucose ABC transporter permease GlcU;
36-289 1.65e-30

glucose ABC transporter permease GlcU;


Pssm-ID: 468865  Cd Length: 272  Bit Score: 115.49  E-value: 1.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  36 VVTVLSLTVLVPLYFAVVTALKTPGEAGT---FSLPTTWEWHNFADAWNKVNYPkaALNSAIITVCAVVLTLLTNTFVAY 112
Cdd:NF040932    8 VLVILVIIWLIPLYAMVINGLKSNFEVLStpvLVPPSKPTLSAYYTVWSGLAPP--LINSLIVVIPVALISTFLGAMGAY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 113 AVARNMDKRFFRFLYYFFLAMM--FVPFTVIMLPIAKEMGTLHLDNQL-GLIILYTILGIGTNLFIAIGFIRSIPISLEE 189
Cdd:NF040932   86 FFYRLSERHSILSDFLFSLIALatFIPYQATLVPLTRLEVSLGLFNTYwGLIFALLIFYIPTAALLMSIFIPVLPKYLIE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 190 AARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTIPLAQYVFQSQFTSNYPMAFASYLMA 269
Cdd:NF040932  166 AARIDGASDWTIFWKVVLPLTVPGFISTLIFIFIESWNNFFIPLVLTTTPSMRLIPVAVRSYTGGYGTLYNESFAAAVIA 245

                         250       260
                  ....*....|....*....|
gi 1468626409 270 MAPVLIVYIFAQKWVVGGVM 289
Cdd:NF040932  246 SIVPLLIFIFLGRYFIRGLA 265
malG PRK10998
maltose ABC transporter permease MalG;
91-294 2.98e-16

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 77.06  E-value: 2.98e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  91 NSAIITVCAVVLTLLTNTFVAYAVARNMDKRFFRFLYYFFLAMMF------VPFTVIMLPIAKEMGTLHLDNQLGLIILY 164
Cdd:PRK10998   87 NSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFpavlslVALYALFDRLGQYIPFIGLNTHGGVIFAY 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 165 tILGIGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTi 244
Cdd:PRK10998  167 -LGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYT- 244

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1468626409 245 pLAQYVFQSQFTSNY---PMAFASYLMAMaPVLIVYIFAQKWVVGGVMRGAVK 294
Cdd:PRK10998  245 -LAVGMQQYLNPQNYlwgDFAAAAVLSAI-PITVVFLLAQRWLVGGLTAGGVK 295
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 89-274 1.51e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.69  E-value: 1.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  89 ALNSAIITVCAVVLTLLTNTFVAYAVARNMdKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHLDNQLGLIILYTILG 168
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKR-GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALIL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 169 -----IGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQT 243
Cdd:cd06261    80 allliAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1468626409 244 IPLAQYVFQSQFTSNYPMAFASYLMAMAPVL 274
Cdd:cd06261   160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-290 1.52e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 64.63  E-value: 1.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 108 TFVAYAVARNMDKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHL-DNQLGLIILYTILGIGTNLFIAIGFIRSIPIS 186
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILgHGILPAIILALLGWAGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 187 LEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQsnqtiPLAQYVFQSQFTSNYPMAFASY 266
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPEIQGPV 156

                         170       180
                  ....*....|....*....|....*..
gi 1468626409 267 LM---AMAPVLIVYIFAQKWVVGGVMR 290
Cdd:pfam00528 157 LAaalILLLLNLLVDILQRLLDPRVRK 183
permease_CysT TIGR02139
sulfate ABC transporter, permease protein CysT; This model represents CysT, one of two ...
 158-212 3.21e-03

sulfate ABC transporter, permease protein CysT; This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions]


Pssm-ID: 131194  Cd Length: 265  Bit Score: 38.46  E-value: 3.21e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468626409 158 LGLIILYTILGIGTNL-FIAIGFI--------RSIPISLEEAARIDGASTWRIFWTIIFPLMGP 212
Cdd:TIGR02139 124 LGIKIAFTPLGIVIALvFVSLPFVvrtvqpvlEEIEKELEEAAASLGASRWQTFWRVILPALLP 187
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-294 1.50e-83

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 252.71  E-value: 1.50e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  18 AKPDKIRRDHKVNWWLTAVVTVLSLTVLVPLYFAVVTALKTPGEAGTFS---LPTTWEWHNFADAWNKVNYPKAALNSAI 94
Cdd:COG0395     2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpslLPSEFTLENYRAAFTDGPFGRYLLNSLI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  95 ITVCAVVLTLLTNTFVAYAVARnMDKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHL-DNQLGLIILYTILGIGTNL 173
Cdd:COG0395    82 VAVVSTVLSLLLSSLAAYALAR-FRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLlNTYWGLILPYLAFGLPFGI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 174 FIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTIPLAQYVFQS 253
Cdd:COG0395   161 FLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQG 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1468626409 254 QFTSNYPMAFASYLMAMAPVLIVYIFAQKWVVGGVMRGAVK 294
Cdd:COG0395   241 QYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 30-294 1.38e-55

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 181.12  E-value: 1.38e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  30 NWWLTAVVTVLSLTVLVPLYFAVVTAL-KTPGEAGTFSLPTTWEWHNFADAWNKVNYPKAALNSAIITVCAVVLTLLTNT 108
Cdd:COG3833    15 LGLRHLVLIILAIIALFPILWVVSASFnPGGSLYSSSLIPENFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 109 FVAYAVARNMDKRFFRFLYYFFLAMMFvPFTVIMLPIAKEMGTLH-LDNQLGLIILYTILGIGTNLFIAIGFIRSIPISL 187
Cdd:COG3833    95 LAAYAFSRFRFKGRKAGLLALLLLQMF-PAFLALVALYLLLSALGlLNTLLGLILVYLGGAIPFNTWLMKGYFDTIPKEL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 188 EEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTIPLAQYVFQS-QFTSNYPMAFASY 266
Cdd:COG3833   174 DEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSdQRNTNWGVFAAGA 253

                         250       260
                  ....*....|....*....|....*...
gi 1468626409 267 LMAMAPVLIVYIFAQKWVVGGVMRGAVK 294
Cdd:COG3833   254 VLVAIPIVILFLFLQRYLVSGLTAGGVK 281
ABC_arch_GlcU NF040932
glucose ABC transporter permease GlcU;
36-289 1.65e-30

glucose ABC transporter permease GlcU;


Pssm-ID: 468865  Cd Length: 272  Bit Score: 115.49  E-value: 1.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  36 VVTVLSLTVLVPLYFAVVTALKTPGEAGT---FSLPTTWEWHNFADAWNKVNYPkaALNSAIITVCAVVLTLLTNTFVAY 112
Cdd:NF040932    8 VLVILVIIWLIPLYAMVINGLKSNFEVLStpvLVPPSKPTLSAYYTVWSGLAPP--LINSLIVVIPVALISTFLGAMGAY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 113 AVARNMDKRFFRFLYYFFLAMM--FVPFTVIMLPIAKEMGTLHLDNQL-GLIILYTILGIGTNLFIAIGFIRSIPISLEE 189
Cdd:NF040932   86 FFYRLSERHSILSDFLFSLIALatFIPYQATLVPLTRLEVSLGLFNTYwGLIFALLIFYIPTAALLMSIFIPVLPKYLIE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 190 AARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTIPLAQYVFQSQFTSNYPMAFASYLMA 269
Cdd:NF040932  166 AARIDGASDWTIFWKVVLPLTVPGFISTLIFIFIESWNNFFIPLVLTTTPSMRLIPVAVRSYTGGYGTLYNESFAAAVIA 245

                         250       260
                  ....*....|....*....|
gi 1468626409 270 MAPVLIVYIFAQKWVVGGVM 289
Cdd:NF040932  246 SIVPLLIFIFLGRYFIRGLA 265
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
12-280 1.21e-18

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 84.03  E-value: 1.21e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  12 TGVQAQAKPDKIRRDHKVNWWLTA-VVTVLSLTVLVPLYFAVVTALKtpgEAGTFSLPTTW-EWHNFADAWNKVNYPKAA 89
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLpALLLLLVFVLYPLLYTLYLSFT---DWNLLGPPPEFvGLDNYARLFTDPRFWNAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  90 LNSAIITVCAVVLTLLTNTFVAYAVARNMdkrffrFLYYFFLAMMFVPFTVIML---------------PIAKEMGTLHL 154
Cdd:COG1175    79 GNTLLFTVVSVPLQLVLGLLLALLLNRKL------RGRGFFRTLFFLPWVISPVvvaliwkwlfnpdygLLNALLGALGL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 155 DNQ----------LGLIILYTILGIGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALW 224
Cdd:COG1175   153 EPInwlgdpslalPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIG 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1468626409 225 AWNDFLLPLItLTDQ--SNQTIPLAQYVFQSQFTSNYpMAFASylmAMAPVLIVYIFA 280
Cdd:COG1175   233 ALQVFDLVYV-LTGGgpGNSTTTLVLYIYQTAFQQFD-FGYAS---AIAVVLFLIILV 285
malG PRK10998
maltose ABC transporter permease MalG;
91-294 2.98e-16

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 77.06  E-value: 2.98e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  91 NSAIITVCAVVLTLLTNTFVAYAVARNMDKRFFRFLYYFFLAMMF------VPFTVIMLPIAKEMGTLHLDNQLGLIILY 164
Cdd:PRK10998   87 NSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFpavlslVALYALFDRLGQYIPFIGLNTHGGVIFAY 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 165 tILGIGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQTi 244
Cdd:PRK10998  167 -LGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYT- 244

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1468626409 245 pLAQYVFQSQFTSNY---PMAFASYLMAMaPVLIVYIFAQKWVVGGVMRGAVK 294
Cdd:PRK10998  245 -LAVGMQQYLNPQNYlwgDFAAAAVLSAI-PITVVFLLAQRWLVGGLTAGGVK 295
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 25-284 5.53e-16

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 75.92  E-value: 5.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  25 RDHKVNWWLTAVVTVLSLTVLVPLYFAVVTALkTPGEAGTFsLPTTWEWHNFADAWNKVNYPKAALNSAIITVCAVVLTL 104
Cdd:COG1177     1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSF-NDSWFLTF-PPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLAT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 105 LTNTFVAYAVARnMDKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHLDNQLGLIIL-YTILGIGTNLFIAIGFIRSI 183
Cdd:COG1177    79 VLGTPAALALAR-YRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILaHVVFTLPFVVLVVLARLQGF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 184 PISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLItLTDQSNQTIPLaqYVFQSQFTSNYPMAF 263
Cdd:COG1177   158 DPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLF-LAGPGVTTLPV--YIYSMIRRGISPEIN 234

                         250       260
                  ....*....|....*....|.
gi 1468626409 264 ASYLMAMAPVLIVYIFAQKWV 284
Cdd:COG1177   235 ALSTLLILLSLLLLLLAERLR 255
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
35-289 1.28e-14

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 72.46  E-value: 1.28e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  35 AVVTVLSLTVLVPLYFAVVTAlkTPGEAGTFS-----LPTTWEWHNFADAW------NKVNYPKAALNSAIITVCAVVLT 103
Cdd:PRK10973   14 TMLILGIAVILFPLYVAFVAA--TLDKQAVFAvpmtlIPGTHLLENIANIWvngvgnNSAPFGRMLLNSFVMAFSITVGK 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 104 LLTNTFVAYAVARNMDKRFFRFLYYFFLAMMfVPFTVIMLPIAKEMGTLHLDNQLGLIILyTILGIGTNLFIAIGFIRSI 183
Cdd:PRK10973   92 ITVSMLSAFAIVWFRFPLRNLFFWMIFITLM-LPVEVRIFPTVEVIANLKMLDSYAGLTL-PLMASATATFLFRQFFMTL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 184 PISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQT--IPLAQYVFQSQFTSNYPM 261
Cdd:PRK10973  170 PDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTavAGIKGMIATGEGTTEWNQ 249

                         250       260
                  ....*....|....*....|....*...
gi 1468626409 262 AFASYLMAMAPVLIVYIFAQKWVVGGVM 289
Cdd:PRK10973  250 VMAAMLLTLIPPVVIVLAMQRAFVRGLV 277
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-283 1.29e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 70.58  E-value: 1.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  12 TGVQAQAKPDKIRRDHKVNWWLTAVV-TVLSLTVLVPLYFAVVTALKTpgeagtfSLPTTWEWHNFADAWNKVNYPKAAL 90
Cdd:COG1178   269 ATVGGRARRPRRVKLGRWRWLALALClLLVLLGLLLPLLALLLWSLTK-------ALDDNLTLDNYRFVLLDPSLLRALL 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  91 NSAIITVCAVVLTLLTNTFVAYAVARNMDKRFFRFLYYFFLAMMfVPFTVI----MLPIAKEMGTLHLDNQLGLIILYTI 166
Cdd:COG1178   342 NSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYA-VPGIVLglglLLLFNRPLPLLLYGTLAILVLAYVV 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 167 LGIGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLItLTDQSNQTIPL 246
Cdd:COG1178   421 RFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLL-LRPPGFETLAV 499

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1468626409 247 AQYVFQSQFTSNYPMAFASYLMAM--APVLIVYIFAQKW 283
Cdd:COG1178   500 LIYQLASSGRYGEAAALALLLVLVslLPVLLLERLLGRR 538
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 89-274 1.51e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.69  E-value: 1.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  89 ALNSAIITVCAVVLTLLTNTFVAYAVARNMdKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHLDNQLGLIILYTILG 168
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKR-GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALIL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 169 -----IGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQSNQT 243
Cdd:cd06261    80 allliAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1468626409 244 IPLAQYVFQSQFTSNYPMAFASYLMAMAPVL 274
Cdd:cd06261   160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-290 1.52e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 64.63  E-value: 1.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 108 TFVAYAVARNMDKRFFRFLYYFFLAMMFVPFTVIMLPIAKEMGTLHL-DNQLGLIILYTILGIGTNLFIAIGFIRSIPIS 186
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILgHGILPAIILALLGWAGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 187 LEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITLTDQsnqtiPLAQYVFQSQFTSNYPMAFASY 266
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPEIQGPV 156

                         170       180
                  ....*....|....*....|....*..
gi 1468626409 267 LM---AMAPVLIVYIFAQKWVVGGVMR 290
Cdd:pfam00528 157 LAaalILLLLNLLVDILQRLLDPRVRK 183
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 21-284 2.50e-12

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 65.94  E-value: 2.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  21 DKIRRDHKVNWWLTAVVTVLSLTVLVPLYFAVVTALKTPGEAGTFSLPTTWEwhNFADAWNKVNYPKAALNSAIITVCAV 100
Cdd:COG1176     3 AALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGFTLE--NYARLFTDPLYLKVLLRTLWIALLTT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 101 VLTLLTNTFVAYAVARnMDKRFFRFLYYFFLAMMFVPFTVIM---LPIAKEMGTL-HLDNQLGLI-----ILYTILGIG- 170
Cdd:COG1176    81 LICLLLGYPIAYFLAR-APPRWRNLLLLLVILPFWTSFLVRTyawIVLLGRNGLLnSLLLALGLIdeplrLLYTEFAVVi 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 171 ----TNLFIAI----GFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLITltdQSNQ 242
Cdd:COG1176   160 glvyVYLPFMVlplyAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALL---GGGK 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1468626409 243 TIPLAQYVFQSQFTS-NYPMAFASYLMAMAPVLIVYIFAQKWV 284
Cdd:COG1176   237 VLMIGNLIYQQFLSAlNWPLAAALAVVLLLIVLLVLLLYLRLL 279
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
30-287 6.90e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 62.49  E-value: 6.90e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409  30 NWWLTAVVTVLSLTVLVPLYFAVVTALktpgeagtfslptTWEWHNFADAWNKVNYPKAALNSAIITVCAVVLTLLTNTF 109
Cdd:COG1178    10 RLLLLLLALLLALLVLLPLLALLLRAF-------------TDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 110 VAYAVARnMDKRFFRFLYYFFLAMMFVP-----FTVIML-----PIAKEMGTL------HLDNQLGLIILYTILGIGTNL 173
Cdd:COG1178    77 LAWLLAR-TDFPGRRLLRWLLLLPLALPpyvvaLAWIALfgpngLLNTLLRALfgleppDIYGLGGIILVLVLFNYPYVY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 174 FIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFLLPLItlTDQSNQTIPLAQYVfQS 253
Cdd:COG1178   156 LLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLV--LGGGYTTLTTAIYQ-AW 232

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1468626409 254 QFTSNYPMAFASYLMAMAPVLIVyIFAQKWVVGG 287
Cdd:COG1178   233 LGDFDLGAAAALALVLLLLVLLL-LLLERRLRRR 265
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 158-223 3.28e-07

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 50.52  E-value: 3.28e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468626409 158 LGLIILYTILGIGTNL-FIAIGF--------IRSIPISLEEAARIDGASTWRIFWTIIFPLMGPinatiAILTAL 223
Cdd:COG0555   128 LGIKVAFTPLGIVLAQtFVSLPFvvrtvqpvLEELDPELEEAAATLGASRWQTFRRVILPLLLP-----ALLTGF 197
modB PRK09421
molybdate ABC transporter permease subunit;
180-251 7.61e-06

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 46.07  E-value: 7.61e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468626409 180 IRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWNDFllpLITLTDQSN-----QTIPLAQYVF 251
Cdd:PRK09421  115 LEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEF---GATITFVSNipgetQTIPSAMYTL 188
cysT CHL00187
sulfate transport protein; Provisional
 153-223 1.88e-05

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 45.01  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 153 HLDNQLGLIILYTILGIG-TNLFIAIGF--------IRSIPISLEEAARIDGASTWRIFWTIIFPLMGPinatiAILTAL 223
Cdd:CHL00187  124 HLLSHLGIQIVFTKLGVLlAMIFVSFPFvvrtiqpvLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIP-----ALLTGL 198
malF PRK10999
maltose ABC transporter permease MalF;
160-227 1.98e-04

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 42.64  E-value: 1.98e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468626409 160 LIILYTILGIGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMgpINATIAILTALWAWN 227
Cdd:PRK10999  378 ILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLL--IKPLTPLMIASFAFN 443
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 167-223 7.17e-04

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 40.46  E-value: 7.17e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1468626409 167 LGIGTNLFIAIgfIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPinaTIAILTAL 223
Cdd:COG4209   189 AGWGSIIYLAA--ITGIDPELYEAAAIDGAGRWQQIWHITLPGIRP---TIVILLIL 240
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 158-225 2.21e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 158 LGLIILYTILGIG-TNLFIAIGF---------IRSIPISLE-----EAARIDGASTWRIFWTIIFP-LMGPI--NATIAI 219
Cdd:COG1173   128 LLAIALVAVLGPGlLNVILALGLtgwpgyarlVRAQVLSLRereyvEAARALGASPLRIIFRHILPnVLPPLivQATLGI 207


                  ....*.
gi 1468626409 220 LTALWA 225
Cdd:COG1173   208 ASAILA 213
permease_CysT TIGR02139
sulfate ABC transporter, permease protein CysT; This model represents CysT, one of two ...
 158-212 3.21e-03

sulfate ABC transporter, permease protein CysT; This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions]


Pssm-ID: 131194  Cd Length: 265  Bit Score: 38.46  E-value: 3.21e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468626409 158 LGLIILYTILGIGTNL-FIAIGFI--------RSIPISLEEAARIDGASTWRIFWTIIFPLMGP 212
Cdd:TIGR02139 124 LGIKIAFTPLGIVIALvFVSLPFVvrtvqpvlEEIEKELEEAAASLGASRWQTFWRVILPALLP 187
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
169-228 8.21e-03

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 37.11  E-value: 8.21e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468626409 169 IGTNLFIAIGFIRSIPISLEEAARIDGASTWRIFWTIIFPLMGPINATIAILTALWAWND 228
Cdd:PRK10561  155 ISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFD 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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