|
Name |
Accession |
Description |
Interval |
E-value |
| PFKA_PPi_Ttgales |
NF041103 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
5-404 |
2.21e-119 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 469029 Cd Length: 406 Bit Score: 353.01 E-value: 2.21e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFIPEP-RTVDIDYRMADSIFNQGGSFLQMSRFKP--KDS 81
Cdd:NF041103 1 LAILVGGGPAPGINSVISAVTIEAINHGWEVLGIYDGFKHLAKGDTsKVIPLTIDDVSRIHFRGGSILGTSRANPtkSEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 82 DFENNfnLKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKkypIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAVIA 161
Cdd:NF041103 81 DLENV--VDTLKELGVTHLVTIGGDDTAFSASKVAKYAGGR---IRVVHVPKTIDNDLPLPEGIPTFGFETARHVGVELV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 162 RAVYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYGAAVISE 241
Cdd:NF041103 156 KNLMEDARTTNRWYFVVAMGRKAGHLALGIGKAAGATLTIIPEEFREEKITLQTVVDILVGSIIKRLAMGRNYGVAVLAE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 242 GVFHALSDEEIRKSGiHFTYDDHGHPELGKVSKAHIFNEMIEKRVKELGLKVKSRPVELGYEIRCQTPIAYDLTYCSELG 321
Cdd:NF041103 236 GLIEKIDPEDLEALG-GVERDEHGHIRLAEINFGEILKKAVKKRLKELGIKITIVDKNIGYELRCADPIPFDIEYTRDLG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 322 IGVHKLFTEGKTGCMVYVDsEGNVSPLYLKDLQDPASGKIPPRLVDIHSDKftsvvenilnaitpadYEEARKYVPNPEE 401
Cdd:NF041103 315 YGAVRFLLEGGTGAMISIQ-NGRFVPIPFEDMLDPKTGRTRVRMVDVESES----------------YRIARRYMIRLEK 377
|
...
gi 2253285072 402 FDF 404
Cdd:NF041103 378 EDF 380
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
5-378 |
5.76e-91 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 278.11 E-value: 5.76e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKPKDSDFE 84
Cdd:COG0205 4 IGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLL--EGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNLKFFTDNNIKLLVTVGGDDTASTANRIAKFleskkYPIANIHVPKTIDNDLPlpkGT-PTFGYESAKDKGAVIARA 163
Cdd:COG0205 82 REKALENLKKLGIDALVVIGGDGSLDGAAKLAEE-----YGIPVVGIPKTIDNDLP---GTdYTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 164 VYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMfnktEITVEKIvnmvISSIIKRKIMGMDYGAAVISEGV 243
Cdd:COG0205 154 LRDTAASHERVFVVEVMGRHAGWLALAAGLAGGADLILIPEV----PFDLDKL----LEKLKERRKRGKGYSIIVVAEGA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 244 FHALSDEEIRKsgihfTYDDHGHPELGkvSKAHIFNEMIEKRvkelgLKVKSRPVELGYEIRCQTPIAYDLTYCSELGIG 323
Cdd:COG0205 226 GDEDGEAVLEA-----DTDAFGHVRLG--GIGEYLAKEIEER-----TGIETRVTVLGHLQRGGSPSAFDRVLASRLGAA 293
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2253285072 324 VHKLFTEGKTGCMVYVdSEGNVSPLylkDLQDPASGKippRLVDIHSDKFTSVVE 378
Cdd:COG0205 294 AVELLLEGKTGVMVGI-RRGEIVLV---PLEEVANKE---KPVDPDSPLIQLARE 341
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-337 |
1.16e-48 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 168.25 E-value: 1.16e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 4 AIAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKpkdsDF 83
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLV--EGDIKELDWESVSDIINRGGTIIGSARCK----EF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 84 ENN-------FNLKfftDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLplpKGTP-TFGYESAKD 155
Cdd:cd00363 76 RTEegrakaaENLK---KHGIDALVVIGGDGSYTGADLLTEEWPSKYQGFNVIGLPGTIDNDI---KGTDyTIGFDTALK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 156 KGAVIARAVYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEmfnktEITVEKIVNMVISSIIKRKIMGMDYG 235
Cdd:cd00363 150 TIVEAIDRIRDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPE-----EPAADEWEEEMVDVIKKRRERGKRHG 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 236 AAVISEGVFhalsdeeirksgihftyddhghPELGKVSKAHIFNEMIEKRvkelgLKVKSRPVELGYEIRCQTPIAYDLT 315
Cdd:cd00363 225 IVIVAEGAI----------------------DFIPKPITEKLLAKLVEER-----LGFDTRATVLGHVQRGGTPTAFDRI 277
|
330 340
....*....|....*....|..
gi 2253285072 316 YCSELGIGVHKLFTEGKTGCMV 337
Cdd:cd00363 278 LASRLGAEAVELLLEGTGGTPV 299
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
5-322 |
4.62e-41 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 146.33 E-value: 4.62e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKPkdsdFE 84
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLV--EGDIDELTWRDVSGILNRGGTILGTSRSKP----FK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNLK----FFTDNNIKLLVTVGGDDTASTANRIAkflESKKYPIanIHVPKTIDNDLPlpkGTP-TFGYESAKDkgaV 159
Cdd:pfam00365 76 TEEGREkiaeNLKKLGIDALVVIGGDGSLTGANKLS---EERGIPV--VGIPKTIDNDIP---GTDyTIGFDTALN---T 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 160 IARAV---YVDARTSGNWFVLAAMGRSAGHLAF--GIGEACHYpmIVIPEMfnktEITVEKIVNmvissIIKRKIMGMDY 234
Cdd:pfam00365 145 IVEAIdriRDTASSHNRVFVVEVMGRHCGWLALmaGLAGGADA--ILIPEI----PFDIEELCE-----KIKELRKGKRF 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 235 GAAVISEGVFHAlsdeeirksgihftyddhghpelgkvskahifnEMIEKRVKElGLKVKSRPVELGYEIRCQTPIAYDL 314
Cdd:pfam00365 214 SIIVVAEGASDG---------------------------------EFLAKLIEE-GTGIETRVTVLGHVQRGGTPSAFDR 259
|
....*...
gi 2253285072 315 TYCSELGI 322
Cdd:pfam00365 260 ILATRLGV 267
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
5-337 |
1.40e-40 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 146.68 E-value: 1.40e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLH-HGYRVIGLHEGYTGLFipEPRTV-DIDYRMADSIFNQGGSFLQMSRFKPKDSD 82
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAIAeYGWEVIGIRDGWRGLL--EGDTVpLLDLEDVRGILPRGGTILGSSRTNPFKYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 83 FENNFNLKF-FTDNNIKLLVTVGGDDTASTANRIAKflesKKYPIanIHVPKTIDNDLplpKGTP-TFGYESAKDKGAVI 160
Cdd:TIGR02483 80 EDGDDKIVAnLKELGLDALIAIGGDGTLGIARRLAD----KGLPV--VGVPKTIDNDL---EATDyTFGFDTAVEIATEA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 161 ARAVYVDARTSGNWFVLAAMGRSAGHLAF--GIGEACHYpmIVIPEmfnkteitVEKIVNMVISSIIKRKIMGMDYGAAV 238
Cdd:TIGR02483 151 LDRLHTTAESHHRVMVVEVMGRHAGWIALhsGIAGGADV--ILIPE--------IPFDIDSVCEKVRERFARGKRFAIVV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 239 ISEGVFHALSDEEIRKSGIhftyDDHGHPELGKVSKAhiFNEMIEKRvkelgLKVKSRPVELGYEIRCQTPIAYDLTYCS 318
Cdd:TIGR02483 221 VAEGAKPKGGEMVVQEGVK----DAFGHVRLGGIGNW--LAEEIERR-----TGIETRATVLGHLQRGGSPSAFDRVLAT 289
|
330
....*....|....*....
gi 2253285072 319 ELGIGVHKLFTEGKTGCMV 337
Cdd:TIGR02483 290 RFGVAAVDLVHEGQFGHMV 308
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
5-337 |
2.41e-38 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 140.60 E-value: 2.41e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKP-KDSDF 83
Cdd:PRK03202 4 IGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLL--EGDIVKLDLKSVSDIINRGGTILGSARFPEfKDEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 84 -----ENnfnLKfftDNNIKLLVTVGGDDTASTANRIAKFleskKYPIanIHVPKTIDNDLPlpkGTP-TFGYESAKDkg 157
Cdd:PRK03202 82 rakaiEN---LK---KLGIDALVVIGGDGSYMGAKRLTEH----GIPV--IGLPGTIDNDIA---GTDyTIGFDTALN-- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 158 avIAravyVDA------------RTsgnwFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMfnktEITVEKIVNMvissII 225
Cdd:PRK03202 145 --TA----VEAidrlrdtassheRV----FIVEVMGRHAGDLALHAGIAGGAEVILIPEV----PFDIEELCAK----IK 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 226 KRKIMGMDYGAAVISEGVFHAlsdeeirksgihftyddhghPELGKvskahifneMIEKRvkelgLKVKSRPVELGYEIR 305
Cdd:PRK03202 207 KGRERGKKHAIIVVAEGVMPA--------------------EELAK---------EIEER-----TGLETRVTVLGHIQR 252
|
330 340 350
....*....|....*....|....*....|..
gi 2253285072 306 CQTPIAYDLTYCSELGIGVHKLFTEGKTGCMV 337
Cdd:PRK03202 253 GGSPTAFDRVLASRMGAHAVELLLEGKGGRMV 284
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PFKA_PPi_Ttgales |
NF041103 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
5-404 |
2.21e-119 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 469029 Cd Length: 406 Bit Score: 353.01 E-value: 2.21e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFIPEP-RTVDIDYRMADSIFNQGGSFLQMSRFKP--KDS 81
Cdd:NF041103 1 LAILVGGGPAPGINSVISAVTIEAINHGWEVLGIYDGFKHLAKGDTsKVIPLTIDDVSRIHFRGGSILGTSRANPtkSEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 82 DFENNfnLKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKkypIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAVIA 161
Cdd:NF041103 81 DLENV--VDTLKELGVTHLVTIGGDDTAFSASKVAKYAGGR---IRVVHVPKTIDNDLPLPEGIPTFGFETARHVGVELV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 162 RAVYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYGAAVISE 241
Cdd:NF041103 156 KNLMEDARTTNRWYFVVAMGRKAGHLALGIGKAAGATLTIIPEEFREEKITLQTVVDILVGSIIKRLAMGRNYGVAVLAE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 242 GVFHALSDEEIRKSGiHFTYDDHGHPELGKVSKAHIFNEMIEKRVKELGLKVKSRPVELGYEIRCQTPIAYDLTYCSELG 321
Cdd:NF041103 236 GLIEKIDPEDLEALG-GVERDEHGHIRLAEINFGEILKKAVKKRLKELGIKITIVDKNIGYELRCADPIPFDIEYTRDLG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 322 IGVHKLFTEGKTGCMVYVDsEGNVSPLYLKDLQDPASGKIPPRLVDIHSDKftsvvenilnaitpadYEEARKYVPNPEE 401
Cdd:NF041103 315 YGAVRFLLEGGTGAMISIQ-NGRFVPIPFEDMLDPKTGRTRVRMVDVESES----------------YRIARRYMIRLEK 377
|
...
gi 2253285072 402 FDF 404
Cdd:NF041103 378 EDF 380
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
5-378 |
5.76e-91 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 278.11 E-value: 5.76e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKPKDSDFE 84
Cdd:COG0205 4 IGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLL--EGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNLKFFTDNNIKLLVTVGGDDTASTANRIAKFleskkYPIANIHVPKTIDNDLPlpkGT-PTFGYESAKDKGAVIARA 163
Cdd:COG0205 82 REKALENLKKLGIDALVVIGGDGSLDGAAKLAEE-----YGIPVVGIPKTIDNDLP---GTdYTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 164 VYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMfnktEITVEKIvnmvISSIIKRKIMGMDYGAAVISEGV 243
Cdd:COG0205 154 LRDTAASHERVFVVEVMGRHAGWLALAAGLAGGADLILIPEV----PFDLDKL----LEKLKERRKRGKGYSIIVVAEGA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 244 FHALSDEEIRKsgihfTYDDHGHPELGkvSKAHIFNEMIEKRvkelgLKVKSRPVELGYEIRCQTPIAYDLTYCSELGIG 323
Cdd:COG0205 226 GDEDGEAVLEA-----DTDAFGHVRLG--GIGEYLAKEIEER-----TGIETRVTVLGHLQRGGSPSAFDRVLASRLGAA 293
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2253285072 324 VHKLFTEGKTGCMVYVdSEGNVSPLylkDLQDPASGKippRLVDIHSDKFTSVVE 378
Cdd:COG0205 294 AVELLLEGKTGVMVGI-RRGEIVLV---PLEEVANKE---KPVDPDSPLIQLARE 341
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-337 |
1.16e-48 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 168.25 E-value: 1.16e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 4 AIAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKpkdsDF 83
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLV--EGDIKELDWESVSDIINRGGTIIGSARCK----EF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 84 ENN-------FNLKfftDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLplpKGTP-TFGYESAKD 155
Cdd:cd00363 76 RTEegrakaaENLK---KHGIDALVVIGGDGSYTGADLLTEEWPSKYQGFNVIGLPGTIDNDI---KGTDyTIGFDTALK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 156 KGAVIARAVYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEmfnktEITVEKIVNMVISSIIKRKIMGMDYG 235
Cdd:cd00363 150 TIVEAIDRIRDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPE-----EPAADEWEEEMVDVIKKRRERGKRHG 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 236 AAVISEGVFhalsdeeirksgihftyddhghPELGKVSKAHIFNEMIEKRvkelgLKVKSRPVELGYEIRCQTPIAYDLT 315
Cdd:cd00363 225 IVIVAEGAI----------------------DFIPKPITEKLLAKLVEER-----LGFDTRATVLGHVQRGGTPTAFDRI 277
|
330 340
....*....|....*....|..
gi 2253285072 316 YCSELGIGVHKLFTEGKTGCMV 337
Cdd:cd00363 278 LASRLGAEAVELLLEGTGGTPV 299
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
5-322 |
4.62e-41 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 146.33 E-value: 4.62e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKPkdsdFE 84
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLV--EGDIDELTWRDVSGILNRGGTILGTSRSKP----FK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNLK----FFTDNNIKLLVTVGGDDTASTANRIAkflESKKYPIanIHVPKTIDNDLPlpkGTP-TFGYESAKDkgaV 159
Cdd:pfam00365 76 TEEGREkiaeNLKKLGIDALVVIGGDGSLTGANKLS---EERGIPV--VGIPKTIDNDIP---GTDyTIGFDTALN---T 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 160 IARAV---YVDARTSGNWFVLAAMGRSAGHLAF--GIGEACHYpmIVIPEMfnktEITVEKIVNmvissIIKRKIMGMDY 234
Cdd:pfam00365 145 IVEAIdriRDTASSHNRVFVVEVMGRHCGWLALmaGLAGGADA--ILIPEI----PFDIEELCE-----KIKELRKGKRF 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 235 GAAVISEGVFHAlsdeeirksgihftyddhghpelgkvskahifnEMIEKRVKElGLKVKSRPVELGYEIRCQTPIAYDL 314
Cdd:pfam00365 214 SIIVVAEGASDG---------------------------------EFLAKLIEE-GTGIETRVTVLGHVQRGGTPSAFDR 259
|
....*...
gi 2253285072 315 TYCSELGI 322
Cdd:pfam00365 260 ILATRLGV 267
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
5-337 |
1.40e-40 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 146.68 E-value: 1.40e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLH-HGYRVIGLHEGYTGLFipEPRTV-DIDYRMADSIFNQGGSFLQMSRFKPKDSD 82
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAIAeYGWEVIGIRDGWRGLL--EGDTVpLLDLEDVRGILPRGGTILGSSRTNPFKYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 83 FENNFNLKF-FTDNNIKLLVTVGGDDTASTANRIAKflesKKYPIanIHVPKTIDNDLplpKGTP-TFGYESAKDKGAVI 160
Cdd:TIGR02483 80 EDGDDKIVAnLKELGLDALIAIGGDGTLGIARRLAD----KGLPV--VGVPKTIDNDL---EATDyTFGFDTAVEIATEA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 161 ARAVYVDARTSGNWFVLAAMGRSAGHLAF--GIGEACHYpmIVIPEmfnkteitVEKIVNMVISSIIKRKIMGMDYGAAV 238
Cdd:TIGR02483 151 LDRLHTTAESHHRVMVVEVMGRHAGWIALhsGIAGGADV--ILIPE--------IPFDIDSVCEKVRERFARGKRFAIVV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 239 ISEGVFHALSDEEIRKSGIhftyDDHGHPELGKVSKAhiFNEMIEKRvkelgLKVKSRPVELGYEIRCQTPIAYDLTYCS 318
Cdd:TIGR02483 221 VAEGAKPKGGEMVVQEGVK----DAFGHVRLGGIGNW--LAEEIERR-----TGIETRATVLGHLQRGGSPSAFDRVLAT 289
|
330
....*....|....*....
gi 2253285072 319 ELGIGVHKLFTEGKTGCMV 337
Cdd:TIGR02483 290 RFGVAAVDLVHEGQFGHMV 308
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
5-337 |
2.41e-38 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 140.60 E-value: 2.41e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKP-KDSDF 83
Cdd:PRK03202 4 IGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLL--EGDIVKLDLKSVSDIINRGGTILGSARFPEfKDEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 84 -----ENnfnLKfftDNNIKLLVTVGGDDTASTANRIAKFleskKYPIanIHVPKTIDNDLPlpkGTP-TFGYESAKDkg 157
Cdd:PRK03202 82 rakaiEN---LK---KLGIDALVVIGGDGSYMGAKRLTEH----GIPV--IGLPGTIDNDIA---GTDyTIGFDTALN-- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 158 avIAravyVDA------------RTsgnwFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMfnktEITVEKIVNMvissII 225
Cdd:PRK03202 145 --TA----VEAidrlrdtassheRV----FIVEVMGRHAGDLALHAGIAGGAEVILIPEV----PFDIEELCAK----IK 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 226 KRKIMGMDYGAAVISEGVFHAlsdeeirksgihftyddhghPELGKvskahifneMIEKRvkelgLKVKSRPVELGYEIR 305
Cdd:PRK03202 207 KGRERGKKHAIIVVAEGVMPA--------------------EELAK---------EIEER-----TGLETRVTVLGHIQR 252
|
330 340 350
....*....|....*....|....*....|..
gi 2253285072 306 CQTPIAYDLTYCSELGIGVHKLFTEGKTGCMV 337
Cdd:PRK03202 253 GGSPTAFDRVLASRMGAHAVELLLEGKGGRMV 284
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
5-337 |
4.00e-34 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 132.09 E-value: 4.00e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTfLHHGYRV---IGLHEGYTGlFIPEpRTVDIDYRMADSIFNQGGSFLQMSRfkpkdS 81
Cdd:PTZ00286 90 AGIVTCGGLCPGLNVVIRELVMN-LINNYGVktiYGAKYGYKG-LYKE-DWIKLDPKDVKTIHRLGGTILGSSR-----G 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 82 DFENNFNLKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGtpTFGYESAKDKGAVIA 161
Cdd:PTZ00286 162 GFDPKVMVDTLIRHGINILFTLGGDGTHRGALAIYKELRRRKLNISVVGIPKTIDNDIPIIDE--SFGFQTAVEEAQNAI 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 162 RAVYVDARTSGNWF-VLAAMGRSAGHLAFGIGEACHYPMIV-IPEMfnktEITVEKIVNMvissiIKRKIMGMDYGAAVI 239
Cdd:PTZ00286 240 RAAYVEAKSAKNGVgIVKLMGRDSGFIALHASVASADVNVClIPEF----DIPLEGVLEY-----IEQRLQKKGHCVIVV 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 240 SEGVFHALSDEEIRKSgihftYDDHGHPELGKVSKahIFNEMIEKRVKELGLKVKSRPVELGYEIRCQTPIAYDLTYCSE 319
Cdd:PTZ00286 311 AEGAGQSLKDADLDLG-----TDASGNKKLWDIGV--YLKDEITKYLKKKKPEHTVKYIDPSYMIRAVPANAADAKFCTQ 383
|
330
....*....|....*....
gi 2253285072 320 LG-IGVHKLFTeGKTGCMV 337
Cdd:PTZ00286 384 LAqNAVHGAMA-GFTGFII 401
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
5-405 |
4.45e-32 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 129.00 E-value: 4.45e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSV---AKTFlHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGG-SFLQMSRFKPKD 80
Cdd:PTZ00287 180 IGIILSGGPAPGGHNVISGIydyAKRY-NEQSQVIGFLGGIDGLY--SKNYVTITDSLMNRFRNLGGfNMLWSGRGKVRN 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 81 SD----FENnfnlkFFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKDK 156
Cdd:PTZ00287 257 KDdliaIEN-----IVAKLKLNGLVIIGGDGSNSNAALISEYFAERQIPISIIGIPKTIDGDLKSEAIEISFGFDTATKT 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 157 GAVIARAVYVDARTSGN-WFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYG 235
Cdd:PTZ00287 332 YSEVIGNLCTDVKTGHNvYHVVRVMGRSASHVVLECALQTRPNIVLIGEEVEKENLSLKDIVSNIVNTILKRRSLNKNYG 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 236 AAVISEGVFHALSDEEIRKSGIHFTYDD--------------------------------HGHPELGKVSKAHIFNEMIE 283
Cdd:PTZ00287 412 VILIPEGLIEFVPEMKILIGELNVILKEgpfdasklkhsrevwdflpsiirdqllmdresTGYIQVGKIATERLIIVLVE 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 284 KRVKEL---GLKVKSRPVELGYEIRCQTPIAYDLTYCSELGIGVHKLFTEGKTGCMVYV----DSEGNVSP-----LYLK 351
Cdd:PTZ00287 492 SELAKLndnNLNIQFMAHYLGYEGRCAIPSNFDCNYCYALGYNAALLIDHKKTGYMSIIqnleDSYANWIPaaipfLRIM 571
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 2253285072 352 DLQDPASGKIPPR----LVDIHSDKFtSVVENILNAITPADYEEArkyvPNPEEFDFH 405
Cdd:PTZ00287 572 HVNRDNTGKEFPAvkryLVDLNSPLF-NVLKEVRSLWSLYDLYRS----PGPIQFNGH 624
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
5-360 |
2.51e-29 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 115.97 E-value: 2.51e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFkPKDSDFE 84
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLI--AGDIVPLDRYSVSDIINRGGTFLGSARF-PEFKDEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNF----NLKFFtdnNIKLLVTVGGDDTAstanRIAKFLESKKYPIanIHVPKTIDNDLPlpkGTP-TFGYESAKDKgAV 159
Cdd:cd00763 80 GQAkaieQLKKH---GIDALVVIGGDGSY----MGAMRLTEHGFPC--VGLPGTIDNDIP---GTDyTIGFDTALNT-VV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 160 IARAVYVDARTSGN-WFVLAAMGRSAGHLAFGIGEACHYPMIVIPEmfnkTEITVEKIVNMVISSIIKRKimgmDYGAAV 238
Cdd:cd00763 147 EAIDRIRDTSSSHQrISVVEVMGRHCGDIALAAGIAGGAEFIVIPE----AEFDREEVANRIKAGIERGK----KHAIVV 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 239 ISEGVfhalsdeeirksgihftYDdhghpelgkvskAHIFNEMIEKRVkelglKVKSRPVELGYEIRCQTPIAYDLTYCS 318
Cdd:cd00763 219 VAEGV-----------------YD------------VDELAKEIEEAT-----GFETRATVLGHIQRGGSPTAFDRILAS 264
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2253285072 319 ELGIGVHKLFTEGKTGCMVYVDSEGNVSPLYLKDLQDPASGK 360
Cdd:cd00763 265 RMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMKPFK 306
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
5-346 |
3.76e-28 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 116.12 E-value: 3.76e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSV--AKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGsFLQMSRFKPKdSD 82
Cdd:cd00765 75 IGIVLSGGQAPGGHNVISGLfdYLKERAKGSTLYGFKGGPAGIL--KCDYIELNAEYIQPYRNTGG-FDMICSGRTK-IE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 83 FENNFNLKFFT--DNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAVI 160
Cdd:cd00765 151 TEDQFKQAEETakKLDLDALVVIGGDDSNTNAALLAENFRSKGLKTRVIGVPKTIDGDLKNKEIETSFGFDTATKIYSEL 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 161 ARAVYVDARTSGN-WFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYGAAVI 239
Cdd:cd00765 231 IGNVMRDARSTGKyWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITDYMVDVICKRAELGYNFGVVLV 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 240 SEGV------------------------FHALSDEEIRK----------SGIHFTY-------------DDHGHPELGKV 272
Cdd:cd00765 311 PEGLiefipevkeliaelneilanevveFNGLWKKKLTEqslklfdllpKGVYLPLfieaiqeqlmlerDPHGNVQVSRI 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 273 SKAHIFNEMIEKRV----KELGLKVKSRPVE--LGYEIRCQTPIAYDLTYCSELGIGVHKLFTEGKTGcmvYVDSEGNVS 346
Cdd:cd00765 391 ETEKLLIQMVETRLekmkQAGAYKGQFMGQShfFGYEGRCAFPSNFDADYCYALGYGAGVLLNSGKTG---YISSVGNLA 467
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
5-339 |
5.68e-28 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 115.79 E-value: 5.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSV--AKTFLHHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGG-SFLQMSRFKPKDs 81
Cdd:PRK07085 73 VGVILSGGQAPGGHNVIAGLfdGLKKLNPDSKLFGFIGGPLGLL--NGKYIEITEEVIDEYRNTGGfDMIGSGRTKIET- 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 82 dfENNFN--LKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLplpKGT---PTFGYESA-KD 155
Cdd:PRK07085 150 --EEQKEacLETVKKLKLDGLVIIGGDDSNTNAAILAEYFAKHGCKTQVIGVPKTIDGDL---KNEfieTSFGFDTAtKT 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 156 KGAVI---ARavyvDARTS-GNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMG 231
Cdd:PRK07085 225 YSEMIgniSR----DALSAkKYWHFIKLMGRSASHIALECALQTHPNICLISEEVAEKKMSLQDIVHYIASVIADRAAKG 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 232 MDYGAAVISEGV------------------------FHALSDEEIRKSGIHF-------TY---------------DDHG 265
Cdd:PRK07085 301 KNYGVILIPEGLiefipemkslikelnsllaeneseFKGLDTEAQREYIISKlspesakLFkslpediarqllldrDPHG 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 266 HPELGKVSKAHIFNEMIEKRVKEL----GLKVKSRPVE--LGYEIRCQTPIAYDLTYCSELGIGVHKLFTEGKTGCMVYV 339
Cdd:PRK07085 381 NVQVSKIETEKLLIEMVKKELEKLkpegKYKGPFSAIShfFGYEGRSAFPSNFDADYCYALGYTAALLILNGKTGYMSTI 460
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-311 |
3.99e-24 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 103.02 E-value: 3.99e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 1 MKEAIAILTGGGPAPGMN-TVVGSVAKTFLHHGY-RVIGLHEGYTGlfIPEPRTVDIDYRMADSIF---NQGGSFLQMSR 75
Cdd:PRK14072 2 MKGNALYAQSGGPTAVINaSAAGVIEEARKHKKIgKVYGARNGIIG--ILDEDLIDLSKESDEALAalaHTPSGALGSCR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 76 FKPKDsdFENNFN-----LKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGy 150
Cdd:PRK14072 80 YKLKS--LEEDRAeyerlLEVFKAHDIGYFFYNGGNDSMDTALKVSQLAKKMGYPIRCIGIPKTIDNDLPGTDHCPGFG- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 151 eSAKDKGAVIARAVYVDAR---TSGNWFVLAAMGRSAGHLAFGIGEACHYP-----MIVIPEM-FNkteitVEKIVNMVI 221
Cdd:PRK14072 157 -SAAKYIATSVLEAALDVAamaNTSKVFILEVMGRHAGWLAAAAALAKQNPddaphLIYLPERpFD-----EEKFLADVR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 222 SSIIKRKimgmdYGAAVISEGVfhalSDEE---IRKSGIHFtyDDHGHPELGKVSkahifnEMIEKRVKE-LGLKVKSrp 297
Cdd:PRK14072 231 AIVKRYG-----YCVVVVSEGI----RDADgkfIAEAGLAE--DAFGHAQLGGVA------PVLANLIKEkLGKKVHW-- 291
|
330
....*....|....
gi 2253285072 298 VELGYEIRCQTPIA 311
Cdd:PRK14072 292 AVLDYLQRAARHIA 305
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
5-346 |
5.17e-23 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 101.02 E-value: 5.17e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHH--GYRVIGLHEGYTGlfIPEPRTVDIDyrmADSIF---NQGGsFLQMSRFKPK 79
Cdd:PLN02251 99 IGVVLSGGQAPGGHNVISGIFDYLQEHakGSVLYGFKGGPAG--IMKCKYVELT---AEFIYpyrNQGG-FDMICSGRDK 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 80 dsdFENNFNLKFFTDNNIKL----LVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKD 155
Cdd:PLN02251 173 ---IETPEQFKQAEETATKLdldgLVVIGGDDSNTNACLLAEYFRAKNLKTRVIGCPKTIDGDLKSKEVPTSFGFDTACK 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 156 KGAVIARAVYVDARTSGNWF-VLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDY 234
Cdd:PLN02251 250 IYSEMIGNVMIDARSTGKYYhFVRLMGRAASHITLECALQTHPNITIIGEEVAAKKLTLKNVTDYIVDVICKRAELGYNY 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 235 GAAVISEG-------VFHALSD-EEIRKSGIhftYDDHGH---------------------PEL-------GKVSKAHIF 278
Cdd:PLN02251 330 GVILIPEGlidfipeVQHLIAElNEILAHDV---VDEEGHwkkklkpqslqlfdflphaiqEQLmlerdphGNVQVAKIE 406
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2253285072 279 NE-----MIE----KRVKELGLK--VKSRPVELGYEIRCQTPIAYDLTYCSELGIGVHKLFTEGKTGcmvYVDSEGNVS 346
Cdd:PLN02251 407 TEkmliqMVEteleKRKQEGSYKghFKGQSHFFGYEGRCGLPTNFDATYCYALGYGAGALLHSGKTG---LISSVGNLA 482
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
6-337 |
2.69e-21 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 95.32 E-value: 2.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 6 AILTGGGPAPGMNTVVGSVAKTfLHHGY---RVIGLHEGYTGlFIPEPR--TVDIDYRMADSIFNQGGSFLQMSRfKPKD 80
Cdd:PRK06830 84 AIVTCGGLCPGLNDVIRAIVLE-LHHHYgvrRILGIRYGYQG-LIPRYGhdPVELTPEVVADIHEFGGTILGSSR-GPQD 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 81 SDfEnnfNLKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPkgTPTFGYESAKDKGAVI 160
Cdd:PRK06830 161 PE-E---IVDTLERMNINILFVIGGDGTLRGASAIAEEIERRGLKISVIGIPKTIDNDINFI--QKSFGFETAVEKATEA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 161 ARAVYVDARTSGNWFVLAA-MGRSAGHLAFGIGEACHYPMIV-IPEMfnktEITVEKiVNMVISSIIKRKImgmDYGAAV 238
Cdd:PRK06830 235 IRCAHVEANGAPNGIGLVKlMGRHSGFIAAYAALASKDVNFVlIPEV----PFDLEG-PNGLLAALEKRLA---ERGHAV 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 239 I--SEGVFHALSDEEIRKsgihftyDDHGHPELGKVSkahifnEMIEKRVKELgLKVKSRPVEL-----GYEIRCQTPIA 311
Cdd:PRK06830 307 IvvAEGAGQELFDDTGET-------DASGNPKLGDIG------LFLKDRIKEY-FKARGIPINLkyidpSYIIRSVPANA 372
|
330 340
....*....|....*....|....*..
gi 2253285072 312 YDLTYCSELG-IGVHKLFTeGKTGCMV 337
Cdd:PRK06830 373 NDSVYCGFLGqNAVHAAMA-GKTGMVV 398
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
6-337 |
6.90e-20 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 90.64 E-value: 6.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 6 AILTGGGPAPGMNTVVGSVAKTFLHHGYR-VIGLHEGYTGLFIPEPRTVDIDYRMADSIFNQGGSFLQMSRFKPKDSDFE 84
Cdd:PLN02884 57 AIVTCGGLCPGLNDVIRQIVFTLEIYGVKnIVGIPFGYRGFFEKGLSEMPLSRKVVQNIHLSGGSLLGVSRGGAKTSDIV 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNLKfftdnNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKgtPTFGYESAKDKGAVIARAV 164
Cdd:PLN02884 137 DSIEAR-----GINMLFVLGGNGTHAGANAIHNECRKRKMKVSVVGVPKTIDNDILLMD--KTFGFDTAVEEAQRAINSA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 165 YVDARTSGNWF-VLAAMGRSAGHLAFGIGEAC-HYPMIVIPEMfnKTEITVEKIVNMVISSIIKRKimgmdyGAAVISeg 242
Cdd:PLN02884 210 YIEAHSAYHGIgLVKLMGRSSGFIAMHASLASgQVDICLIPEV--PFTLDGPNGVLRHLEHLIETK------GSAVVC-- 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 243 VFHALSDEEIRKSGihfTYDDHGHPELGKVSkAHIFNEmIEKRVKELGLKVKSRPVELGYEIRCQTPIAYDLTYCSELGI 322
Cdd:PLN02884 280 VAEGAGQDLLQKTN---ATDASGNPVLGDIG-VHLQQE-IKKHFKDIGVPADVKYIDPTYMIRACRANASDAILCTVLGQ 354
|
330
....*....|....*.
gi 2253285072 323 -GVHKLFTeGKTGCMV 337
Cdd:PLN02884 355 nAVHGAFA-GFSGITV 369
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
7-339 |
3.09e-19 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 90.42 E-value: 3.09e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 7 ILTGGGPAPGMNTVVGSVAKTFL-HHGYRVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSRFKPKDSDFEN 85
Cdd:PTZ00468 108 VLSGGQASGGHNVIAGLMSYIKLcNQSSQLFGFLGGPEGVY--SERYRELTEDDINGILNQGGFNIICSGRHKIETEEQM 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 86 NFNLKFFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAVIARAVY 165
Cdd:PTZ00468 186 RASLEICEKLKLHGLVVIGGDDSNTNAAVLAEYFKRNSSSTVVVGCPKTIDGDLKNEVIETSFGYDTAVKTYSEQIGSIM 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 166 VDARTSGN-WFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYGAAVISEGV- 243
Cdd:PTZ00468 266 DAIKTEGYgYYFVRLMGRSASHITLECGLQTRANMILIGEEIKEENRSLMSIVDEIVEMILKRDSLGKKHGIVLLPEGLi 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 244 -----FHALSDE--------------------EIR----------KSGIHFTYDDHGHPELGKVSKAHIFNEMIEKRVKE 288
Cdd:PTZ00468 346 efipeFETLIKElnlillktndrkqiidslsqEMKtlflelpsdvQNQLLLERDPHGNVQVAKIATEELLVHMAKEKLEE 425
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2253285072 289 LG---LKVKSRPVELGYEIRCQTPIAYDLTYCSELGIGVHKLFTEGKTGCMVYV 339
Cdd:PTZ00468 426 VKkdyILDNVKTHYFGYEGRCALPSNFDASYCFALGHTAAALIDNQRSGYMAVV 479
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
1-337 |
4.56e-17 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 82.04 E-value: 4.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 1 MKEA--IAILTGGGPAPGMNTVVGSVAKTFLHH-GYRVIGLHEGYTGLFIPEPRTVDIDYRMADSIFNQGGSFLQMSR-- 75
Cdd:PRK14071 1 MGEKkrIGILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARPPQYIELDLDQVDDLLRMGGTILGTTNkg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 76 -----------FKPKDSDFENNFNlkfftDNNIKLLVTVGGDDTASTANRIAkflesKKYPIANIHVPKTIDNDLPLPKg 144
Cdd:PRK14071 81 dpfafpmpdgsLRDRSQEIIDGYH-----SLGLDALIGIGGDGSLAILRRLA-----QQGGINLVGIPKTIDNDVGATE- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 145 tPTFGYESAKDKGAVIARAVYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVnmvissi 224
Cdd:PRK14071 150 -VSIGFDTAVNIATEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIR------- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 225 iKRKIMGMDYGAAVISEGVfHALSDEEIRKSgihftyDDHGHPELGKVSKaHIFNEMIEKRVKElglkvkSRPVELGYEI 304
Cdd:PRK14071 222 -ERQEEGKNFCLVVVSEAV-RTEEGEQVTKT------QALGEDRYGGIGQ-YLAEQIAERTGAE------TRVTVLGHIQ 286
|
330 340 350
....*....|....*....|....*....|...
gi 2253285072 305 RCQTPIAYDLTYCSELGIGVHKLFTEGKTGCMV 337
Cdd:PRK14071 287 RGGIPSPRDRLLASAFGVAAVDLIAQGKFDRMV 319
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-204 |
7.38e-17 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 82.56 E-value: 7.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 2 KEAIAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLFIPEPRTVDIDYRMADSIFNQGGSFLQMSR---FKP 78
Cdd:cd00764 3 GKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGGDYIKQAEWESVSNWLQEGGTIIGSARckeFRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 79 KDSDFENNFNLkffTDNNIKLLVTVGGDDTASTAN-----------------RIAKfLESKKYPIANI-HVPKTIDNDLp 140
Cdd:cd00764 83 REGRLQAAYNL---IQRGITNLCVIGGDGSLTGADlfrsewpslleelvkdgKITE-EEVAKYQHLNIvGMVGSIDNDF- 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2253285072 141 lpKGTP-TFGYESAKDKGAVIARAVYVDARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPE 204
Cdd:cd00764 158 --CGTDmTIGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPE 220
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-205 |
7.12e-16 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 79.69 E-value: 7.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 3 EAIAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGL-----FIPEPRTVDIdyrmaDSIFNQGGSFLQMSR-- 75
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLvdggdNIEEAQWEDV-----RGILSLGGTIIGTARck 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 76 -FKPKDSDFENNFNLkffTDNNIKLLVTVGGDDTASTANR--------IAKFLESKK--------YPIANI-HVPKTIDN 137
Cdd:TIGR02478 76 eFRERPGRLKAARNL---VSNGIDALVVIGGDGSLTGADLfreewpslLEELVDTGKitaeqaeeHRHLTIvGLVGSIDN 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2253285072 138 DLPlpkGTP-TFGYESAKDKgavIARAV-YVD--ARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPEM 205
Cdd:TIGR02478 153 DMC---GTDmTIGADSALHR---ICEAIdAISstAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPER 218
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
1-188 |
1.82e-14 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 74.27 E-value: 1.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 1 MKEAIAILTGGGPAPGMNTVVGSVAK--TFLHHGYRVIGLHEGYTGLFIPEPRTVDIDYRM-ADSIFNQGGSFLQMSRFK 77
Cdd:PRK06555 2 AVKKVALLTAGGLAPCLSSAVGGLIEryTEIAPEVEIIAYRSGYQGLLLGDSIEITPAVRAnAGLLHRYGGSPIGNSRVK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 78 ---PKD-------SDFENNfnLKF----FTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDL-PLP 142
Cdd:PRK06555 82 ltnVADcvkrglvKEGENP--LKVaaerLAADGVDILHTIGGDDTNTTAADLAAYLAENGYDLTVVGLPKTIDNDVvPIR 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2253285072 143 KgtpTFGYESAKDKGAVIARAVYVDARTSGNWFVL-AAMGRSAGHLA 188
Cdd:PRK06555 160 Q---SLGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLT 203
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
6-188 |
1.98e-14 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 74.78 E-value: 1.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 6 AILTGGGPAPGMNTVVGSVAKTfLHHGY---RVIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLQMSR-----FK 77
Cdd:PLN02564 91 CIVTCGGLCPGLNTVIREIVCG-LSYMYgvtRILGIDGGYRGFY--SRNTIPLTPKVVNDIHKRGGTILGTSRgghdtSK 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 78 PKDSdfennfnlkfFTDNNIKLLVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKgtPTFGYESAKDKG 157
Cdd:PLN02564 168 IVDS----------IQDRGINQVYIIGGDGTQKGASVIYEEIRRRGLKVAVAGIPKTIDNDIPVID--KSFGFDTAVEEA 235
|
170 180 190
....*....|....*....|....*....|..
gi 2253285072 158 AVIARAVYVDARTSGNWF-VLAAMGRSAGHLA 188
Cdd:PLN02564 236 QRAINAAHVEAESVENGIgLVKLMGRYSGFIA 267
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
5-188 |
4.26e-12 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 67.75 E-value: 4.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLF---IPEPRTVDIdyrmaDSIFNQGGSFLQMSRFKPkDS 81
Cdd:TIGR02478 392 IAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLArhdVRELTWSDV-----EGWVGEGGSELGTNRSLP-GD 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 82 DFEnnFNLKFFTDNNIKLLVTVGGDDTASTANRIAKflESKKYPIANIH---VPKTIDNDLPlpkGTP-TFGYESAKDkg 157
Cdd:TIGR02478 466 DLG--TIAYYFQQHKIDGLIIIGGFEAFEALYQLDA--AREKYPAFRIPmvvIPATISNNVP---GTEySLGSDTALN-- 536
|
170 180 190
....*....|....*....|....*....|....*..
gi 2253285072 158 aVIARavYVDA-RTSG-----NWFVLAAMGRSAGHLA 188
Cdd:TIGR02478 537 -EITE--YCDNiKQSAsaskrRVFVVETMGGYSGYLA 570
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
5-204 |
1.10e-10 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 63.69 E-value: 1.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 5 IAILTGGGPAPGMNTVVGSVAKTFLHHGYRVIGLHEGYTGLfiPEPRTVDIDYRMADSIFNQGGSFLQMSRFKPKDSDFE 84
Cdd:cd00764 392 IAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGL--AKGQIVELGWIDVGGWTGRGGSELGTKRTLPKKDLET 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNlkfFTDNNIKLLVTVGGDDTASTANRIAKflESKKYPIANIH---VPKTIDNDLPlpkGTPtfgYESAKDKgAVIA 161
Cdd:cd00764 470 IAYN---FQKYGIDGLIIVGGFEAYKGLLQLRE--AREQYEEFCIPmvlIPATVSNNVP---GTD---FSLGSDT-ALNA 537
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2253285072 162 RAVYVD------ARTSGNWFVLAAMGRSAGHLAFGIGEACHYPMIVIPE 204
Cdd:cd00764 538 LMKYCDrikqsaSGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFE 586
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
14-257 |
2.78e-10 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 62.36 E-value: 2.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 14 APG-MNTVVGsvaktfLHHGYRVI-GLHEGYTGLF-IPEPRTVDIDYRMADSIFNQGGsfLQMSRFKPKDSDFEN-NFNL 89
Cdd:PTZ00287 848 APGaMNVLCG------LYRRLKLLkGVCIAFYGLYgLLNNKYIIIDDDNIAKHVNQGG--LELTGNSPEHSLFDKeNRNK 919
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 90 KFFTDNNIKL--LVTVGGDDTASTANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAVIARAVYVD 167
Cdd:PTZ00287 920 VCETVTNLQLngLVMPGSNVTITEAALLAEYFLEKKIPTSVVGIPLTGSNNLIHELIETCVGFDSSTKVYASLIGNVLTD 999
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 168 ARTSGN-WFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYGAAVISEGVFHA 246
Cdd:PTZ00287 1000 AVSMPKyWHFIRLMGRSPSHEVLECALQTHPNMVIISEEYGAADKTLWRVVQDIADVVCARAELGKNYGTVLIPDALLMH 1079
|
250
....*....|.
gi 2253285072 247 LSDEEIRKSGI 257
Cdd:PTZ00287 1080 LPHMKILLSEI 1090
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
35-243 |
2.17e-08 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 55.94 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 35 VIGLHEGYTGLFipEPRTVDIDYRMADSIFNQGGSFLqMSRFKPKDSDFEN-NFNLKFFTDNNIKLLVTVGGDDTASTAN 113
Cdd:PLN03028 114 LLGFLGGTEGLF--AQKTLEITDDVLSTYKNQGGYDL-LGRTKDQIRTTEQvNAALAACEALKLDGLVIIGGVTSNTDAA 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 114 RIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAVIARAVYVDARTSGNWF-VLAAMGRSAGHLAFGIG 192
Cdd:PLN03028 191 QLAETFAEAKCKTKVVGVPVTLNGDLKNQFVETNVGFDTICKVNSQLISNVCTDALSAEKYYyFIRLMGRKASHVALECA 270
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2253285072 193 EACHYPMIVIPEMFNKTEITVEKIVNMVISSIIKRKIMGMDYGAAVISEGV 243
Cdd:PLN03028 271 LQSHPNMVILGEEVAASKLTLFDITKQICDAVQARAEQDKNHGVILIPEGL 321
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
85-244 |
6.25e-08 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 54.98 E-value: 6.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 85 NNFNLKFFTDNNIKLLVTVGGDDTAS-----TANRIAKFLESKKYPIANIHVPKTIDNDLPLPKGTPTFGYESAKDKGAV 159
Cdd:PTZ00468 789 NDFLSQLLSFFNMRAIAIVGNSEAATfgaslSEQLICMSLNGMKSEIPVVFVPVCLENSISHQMIETCIGFDSVTKSIST 868
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2253285072 160 IARAVYVDARTSGN-WFVLAAMGRSAGHLAFGIGEACHYPMIVIPEMFNKTE----------ITVEKIVNMVISSIIKRK 228
Cdd:PTZ00468 869 LVGNLLTDSASATKyWYFMKMIGDKTSNVALEVGIQTHPNLVVIPERYADSKlsvygsemagVTLDDIITEICDIICLRS 948
|
170
....*....|....*.
gi 2253285072 229 IMGMDYGAAVISEGVF 244
Cdd:PTZ00468 949 NQGNNFGGLLVSEGLF 964
|
|
| |
