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Conserved domains on  [gi|2523888002|ref|WP_286353970|]
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HNH endonuclease [Geothrix oryzae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3183 COG3183
Predicted restriction endonuclease, HNH family [Defense mechanisms];
191-302 1.24e-36

Predicted restriction endonuclease, HNH family [Defense mechanisms];


:

Pssm-ID: 442416 [Multi-domain]  Cd Length: 112  Bit Score: 127.04  E-value: 1.24e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2523888002 191 PEHREYAEARRLSSERYFFARNPSLRKDAIQVYGTSCQACGFDFGARYGAHGAGYIEVHHKDPLSERaeaewTEEVRTAL 270
Cdd:COG3183     3 EEPKGFTEGAKKEVTHKRYERNPKLRKKAKEHAGGKCEVCGFDFEFVYGELGEGYIEVHHLIPLSEI-----GEGGVDPI 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2523888002 271 SQVAVLCANCHRMVHRKKQALTIEQLKDQLQN 302
Cdd:COG3183    78 EDLVPLCPNCHRMLHRGRPPLSIEELKKLLKR 109
 
Name Accession Description Interval E-value
COG3183 COG3183
Predicted restriction endonuclease, HNH family [Defense mechanisms];
191-302 1.24e-36

Predicted restriction endonuclease, HNH family [Defense mechanisms];


Pssm-ID: 442416 [Multi-domain]  Cd Length: 112  Bit Score: 127.04  E-value: 1.24e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2523888002 191 PEHREYAEARRLSSERYFFARNPSLRKDAIQVYGTSCQACGFDFGARYGAHGAGYIEVHHKDPLSERaeaewTEEVRTAL 270
Cdd:COG3183     3 EEPKGFTEGAKKEVTHKRYERNPKLRKKAKEHAGGKCEVCGFDFEFVYGELGEGYIEVHHLIPLSEI-----GEGGVDPI 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2523888002 271 SQVAVLCANCHRMVHRKKQALTIEQLKDQLQN 302
Cdd:COG3183    78 EDLVPLCPNCHRMLHRGRPPLSIEELKKLLKR 109
HNHc cd00085
HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic ...
 213-285 6.48e-05

HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.


Pssm-ID: 238038 [Multi-domain]  Cd Length: 57  Bit Score: 40.15  E-value: 6.48e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2523888002 213 PSLRKDAIQvYGTSCQACGFDFGARYgahgagyIEVHHKDPLSERAeaewteevRTALSQVAVLCANCHRMVH 285
Cdd:cd00085     1 RSHRLVLLA-RDGLCPYCGKPGGTEG-------LEVDHIIPLSDGG--------NNDLDNLVLLCRKCHRKKH 57
HNH pfam01844
HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic ...
 227-287 1.79e-04

HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.


Pssm-ID: 396422 [Multi-domain]  Cd Length: 47  Bit Score: 38.49  E-value: 1.79e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2523888002 227 CQACGFDFgarygaHGAGYIEVHHKDPLSEraeaewteEVRTALSQVAVLCANCHRMVHRK 287
Cdd:pfam01844   1 CQYCGRPF------HISDALTVDHIIPLSD--------GGADDIENLILLCPSCHNKKHNR 47
 
Name Accession Description Interval E-value
COG3183 COG3183
Predicted restriction endonuclease, HNH family [Defense mechanisms];
191-302 1.24e-36

Predicted restriction endonuclease, HNH family [Defense mechanisms];


Pssm-ID: 442416 [Multi-domain]  Cd Length: 112  Bit Score: 127.04  E-value: 1.24e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2523888002 191 PEHREYAEARRLSSERYFFARNPSLRKDAIQVYGTSCQACGFDFGARYGAHGAGYIEVHHKDPLSERaeaewTEEVRTAL 270
Cdd:COG3183     3 EEPKGFTEGAKKEVTHKRYERNPKLRKKAKEHAGGKCEVCGFDFEFVYGELGEGYIEVHHLIPLSEI-----GEGGVDPI 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2523888002 271 SQVAVLCANCHRMVHRKKQALTIEQLKDQLQN 302
Cdd:COG3183    78 EDLVPLCPNCHRMLHRGRPPLSIEELKKLLKR 109
HNHc cd00085
HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic ...
 213-285 6.48e-05

HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.


Pssm-ID: 238038 [Multi-domain]  Cd Length: 57  Bit Score: 40.15  E-value: 6.48e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2523888002 213 PSLRKDAIQvYGTSCQACGFDFGARYgahgagyIEVHHKDPLSERAeaewteevRTALSQVAVLCANCHRMVH 285
Cdd:cd00085     1 RSHRLVLLA-RDGLCPYCGKPGGTEG-------LEVDHIIPLSDGG--------NNDLDNLVLLCRKCHRKKH 57
HNH pfam01844
HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic ...
 227-287 1.79e-04

HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.


Pssm-ID: 396422 [Multi-domain]  Cd Length: 47  Bit Score: 38.49  E-value: 1.79e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2523888002 227 CQACGFDFgarygaHGAGYIEVHHKDPLSEraeaewteEVRTALSQVAVLCANCHRMVHRK 287
Cdd:pfam01844   1 CQYCGRPF------HISDALTVDHIIPLSD--------GGADDIENLILLCPSCHNKKHNR 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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