|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
3-431 |
2.45e-111 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 334.14 E-value: 2.45e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 3 MNREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRE 82
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHLGSAAY--LGAVALGTTIFNTLFWLFGFLRMGTTGLVAQALGAGDREE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 83 CTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGNDMT----REYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFT 158
Cdd:cd13136 79 AIALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVaalaRQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLIL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 159 AITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLFACYRRILtGIDWAEVVNLKPLRTFFIVNRDIMLR 238
Cdd:cd13136 159 QIVGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLG-KSLSRRLPSKAALKRLFKLNRDIFIR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 239 TFCIVAVYTFFTGASARMDEPAlLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVSV 318
Cdd:cd13136 238 TLALLAAFLFFTALAARLGDVI-LAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLGV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 319 LFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWATAAYFGIF 398
Cdd:cd13136 317 LLALLFFLGGEPIIRLFTDDPA-----VLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLPLL 391
|
410 420 430
....*....|....*....|....*....|...
gi 2552866260 399 YVGYAIIGNNALWLAFTLYMFLRGVLQYFMTHR 431
Cdd:cd13136 392 FLLVPLWGNHGLWLALILFMLLRGLTLALRLPR 424
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
1-428 |
6.62e-62 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 206.53 E-value: 6.62e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 1 MNMNREILRIALPNIVSNITVPLMGIVSTAIAGHWGsdtAATIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNF 80
Cdd:COG0534 4 GPILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLG---TAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 81 RECTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPM 156
Cdd:COG0534 81 EEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADpevlALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 157 FTAITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLFACYRRILTGIdWAEVVNLKPLRTFFIVNRDIM 236
Cdd:COG0534 161 IIMLIGNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRL-RDLRPDRKILKRILRIGLPAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 237 LRTFCIVAVYTFFTGASARMDEPAlLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAV 316
Cdd:COG0534 240 LQQLAESLGFLVLNALVARLGTAA-VAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 317 SVLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWATAAYF- 395
Cdd:COG0534 319 GLLLALLLFLFPEPIIGLFTDDPE-----VIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRl 393
|
410 420 430
....*....|....*....|....*....|....
gi 2552866260 396 -GIFYVGYAIIGNNALWLAFTLYMFLRGVLQYFM 428
Cdd:COG0534 394 pLAYLLAFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
4-431 |
2.25e-58 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 197.65 E-value: 2.25e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 4 NREILRIALPNIVSNITVPLMGIVSTAIAGHWgsDTAATIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFREC 83
Cdd:PRK10367 8 DKALWRLALPMIFSNITVPLLGLVDTAVIGHL--DSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 84 TNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGND----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTA 159
Cdd:PRK10367 86 ARALVQPLLLALGAGALIALLRTPLIDLALHIVGGSEavleQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 160 ITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLFACYRriLTGIDWAEVVNL--KPLRTFFIVNRDIML 237
Cdd:PRK10367 166 VVGNILNIVLDLWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKVLK--LRGISLEMLKTAwrGNFRRLLALNRDIML 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 238 RTFCIVAVYTFFTGASARMDePALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVS 317
Cdd:PRK10367 244 RSLLLQLCFGAITVLGARLG-SDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 318 VLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWAtAAYFGI 397
Cdd:PRK10367 323 LLFSLVYALAGEHIIALLTSLPQ-----IQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVA-AAGFAL 396
|
410 420 430
....*....|....*....|....*....|....
gi 2552866260 398 FYVGYAIIGNNALWLAFTLYMFLRGVLQYFMTHR 431
Cdd:PRK10367 397 TLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRR 430
|
|
| GntT_guanitoxin |
NF041358 |
guanitoxin biosynthesis MATE family efflux transporter GntT; |
9-424 |
7.53e-46 |
|
guanitoxin biosynthesis MATE family efflux transporter GntT;
Pssm-ID: 469250 [Multi-domain] Cd Length: 438 Bit Score: 164.43 E-value: 7.53e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 9 RIALPNIVSNITVPLMGIVSTAIAGHWgSDTAATIGAlAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNMLV 88
Cdd:NF041358 17 RLAIANVLSNIMVPLAGLISVAFLGHL-SEIHHLAGV-ALAGNLFDYLYRILAFLRMGTTGVTAQAVGRDDREAMLLVGL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 89 RALLVAGGMGLLMLLLQYPLGELALWGLNGNDMTRE----YFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNV 164
Cdd:NF041358 95 RNGLIALVLGILILLLQYPLRELGFALLSATPEVKAsgiaYFNARIWGAPAVLLNFVLIGWFLGREKNGLVVLLSVIGNA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 165 AHVLCSLWFAFGLDMGIVGIAYASVIAQWtgVALSALLLFACyrrilTGIDWAEVVNLKP-------LRTFFIVNRDIML 237
Cdd:NF041358 175 ANIALDYLLIIRWGWESTGAGLSYAISQY--LTLLVGLIFVC-----LEIKWQELRAVAGkiwdrsaIKSTFTLNGNIFV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 238 RTFCIVAVYTFFTGASARMDEpALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVS 317
Cdd:NF041358 248 RNLIFISALLIFTNESAAMGT-IIYAENALLLQIIFLSVYFIEGLGFATETLTGNFKGKGASEQLVPLVKVSVGTSLLVG 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 318 VLFVGIYIGWWRELVGLFVDSTapnaaTIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWATAAYFGI 397
Cdd:NF041358 327 LSFAGVCVLFPQTVFGLLTNHT-----EITEQIDIYVPWLLPVLGFSSIAFMLEGYFLGLAEGHTLRNVSLIALTVGFIP 401
|
410 420
....*....|....*....|....*...
gi 2552866260 398 F-YVGYAIIGNNALWLAFTLYMFLRGVL 424
Cdd:NF041358 402 LaIAAWYFHSNHILWLALSLFMIIRMVA 429
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
13-344 |
1.00e-35 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 134.68 E-value: 1.00e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 13 PNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNMLVRALL 92
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLA---AVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 93 VAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNVAHVL 168
Cdd:TIGR00797 78 LALLLGLPVLLVGYFFIDPLLSLMGADgevaELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINII 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 169 CSLWFAFGL--DMGIVGIAYASVIAQWTGVALSALLLFACYRRILTGIDWaEVVNLKPLRTFFIVNRDIMLRTFCIVAVY 246
Cdd:TIGR00797 158 LNYILIFGKfgFLGIVGAALATVISYWLMFLLLLYYIKKAKKIGLKWEGL-LKPDWEVLKRLLKLGLPIAFRVILESLSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 247 TFFTGASARMDePALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVSVLFVGIYIG 326
Cdd:TIGR00797 237 ALLALLVARLG-SIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILIL 315
|
330
....*....|....*...
gi 2552866260 327 WWRELVGLFVDSTAPNAA 344
Cdd:TIGR00797 316 FREFIARLFTNDPEVLEL 333
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
13-167 |
2.38e-11 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 61.81 E-value: 2.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 13 PNIVSNITVPLMGIVSTAIAGHWGSDTaatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNMLVRALL 92
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVA---LAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLI 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2552866260 93 VAGGMGLLMLLLQYPLGELALWGLNGND----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNVAHV 167
Cdd:pfam01554 78 LGLLLSLPIALLVLLFSEPILSLFGQDEevlaLAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNI 156
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
3-431 |
2.45e-111 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 334.14 E-value: 2.45e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 3 MNREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRE 82
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHLGSAAY--LGAVALGTTIFNTLFWLFGFLRMGTTGLVAQALGAGDREE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 83 CTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGNDMT----REYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFT 158
Cdd:cd13136 79 AIALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVaalaRQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLIL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 159 AITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLFACYRRILtGIDWAEVVNLKPLRTFFIVNRDIMLR 238
Cdd:cd13136 159 QIVGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLG-KSLSRRLPSKAALKRLFKLNRDIFIR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 239 TFCIVAVYTFFTGASARMDEPAlLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVSV 318
Cdd:cd13136 238 TLALLAAFLFFTALAARLGDVI-LAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLGV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 319 LFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWATAAYFGIF 398
Cdd:cd13136 317 LLALLFFLGGEPIIRLFTDDPA-----VLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLPLL 391
|
410 420 430
....*....|....*....|....*....|...
gi 2552866260 399 YVGYAIIGNNALWLAFTLYMFLRGVLQYFMTHR 431
Cdd:cd13136 392 FLLVPLWGNHGLWLALILFMLLRGLTLALRLPR 424
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
1-428 |
6.62e-62 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 206.53 E-value: 6.62e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 1 MNMNREILRIALPNIVSNITVPLMGIVSTAIAGHWGsdtAATIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNF 80
Cdd:COG0534 4 GPILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLG---TAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 81 RECTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPM 156
Cdd:COG0534 81 EEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADpevlALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 157 FTAITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLFACYRRILTGIdWAEVVNLKPLRTFFIVNRDIM 236
Cdd:COG0534 161 IIMLIGNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRL-RDLRPDRKILKRILRIGLPAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 237 LRTFCIVAVYTFFTGASARMDEPAlLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAV 316
Cdd:COG0534 240 LQQLAESLGFLVLNALVARLGTAA-VAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 317 SVLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWATAAYF- 395
Cdd:COG0534 319 GLLLALLLFLFPEPIIGLFTDDPE-----VIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRl 393
|
410 420 430
....*....|....*....|....*....|....
gi 2552866260 396 -GIFYVGYAIIGNNALWLAFTLYMFLRGVLQYFM 428
Cdd:COG0534 394 pLAYLLAFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
4-431 |
2.25e-58 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 197.65 E-value: 2.25e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 4 NREILRIALPNIVSNITVPLMGIVSTAIAGHWgsDTAATIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFREC 83
Cdd:PRK10367 8 DKALWRLALPMIFSNITVPLLGLVDTAVIGHL--DSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 84 TNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGND----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTA 159
Cdd:PRK10367 86 ARALVQPLLLALGAGALIALLRTPLIDLALHIVGGSEavleQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 160 ITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLFACYRriLTGIDWAEVVNL--KPLRTFFIVNRDIML 237
Cdd:PRK10367 166 VVGNILNIVLDLWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKVLK--LRGISLEMLKTAwrGNFRRLLALNRDIML 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 238 RTFCIVAVYTFFTGASARMDePALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVS 317
Cdd:PRK10367 244 RSLLLQLCFGAITVLGARLG-SDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 318 VLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWAtAAYFGI 397
Cdd:PRK10367 323 LLFSLVYALAGEHIIALLTSLPQ-----IQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVA-AAGFAL 396
|
410 420 430
....*....|....*....|....*....|....
gi 2552866260 398 FYVGYAIIGNNALWLAFTLYMFLRGVLQYFMTHR 431
Cdd:PRK10367 397 TLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRR 430
|
|
| GntT_guanitoxin |
NF041358 |
guanitoxin biosynthesis MATE family efflux transporter GntT; |
9-424 |
7.53e-46 |
|
guanitoxin biosynthesis MATE family efflux transporter GntT;
Pssm-ID: 469250 [Multi-domain] Cd Length: 438 Bit Score: 164.43 E-value: 7.53e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 9 RIALPNIVSNITVPLMGIVSTAIAGHWgSDTAATIGAlAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNMLV 88
Cdd:NF041358 17 RLAIANVLSNIMVPLAGLISVAFLGHL-SEIHHLAGV-ALAGNLFDYLYRILAFLRMGTTGVTAQAVGRDDREAMLLVGL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 89 RALLVAGGMGLLMLLLQYPLGELALWGLNGNDMTRE----YFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNV 164
Cdd:NF041358 95 RNGLIALVLGILILLLQYPLRELGFALLSATPEVKAsgiaYFNARIWGAPAVLLNFVLIGWFLGREKNGLVVLLSVIGNA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 165 AHVLCSLWFAFGLDMGIVGIAYASVIAQWtgVALSALLLFACyrrilTGIDWAEVVNLKP-------LRTFFIVNRDIML 237
Cdd:NF041358 175 ANIALDYLLIIRWGWESTGAGLSYAISQY--LTLLVGLIFVC-----LEIKWQELRAVAGkiwdrsaIKSTFTLNGNIFV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 238 RTFCIVAVYTFFTGASARMDEpALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVS 317
Cdd:NF041358 248 RNLIFISALLIFTNESAAMGT-IIYAENALLLQIIFLSVYFIEGLGFATETLTGNFKGKGASEQLVPLVKVSVGTSLLVG 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 318 VLFVGIYIGWWRELVGLFVDSTapnaaTIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVMRNSMFWATAAYFGI 397
Cdd:NF041358 327 LSFAGVCVLFPQTVFGLLTNHT-----EITEQIDIYVPWLLPVLGFSSIAFMLEGYFLGLAEGHTLRNVSLIALTVGFIP 401
|
410 420
....*....|....*....|....*...
gi 2552866260 398 F-YVGYAIIGNNALWLAFTLYMFLRGVL 424
Cdd:NF041358 402 LaIAAWYFHSNHILWLALSLFMIIRMVA 429
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
13-344 |
1.00e-35 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 134.68 E-value: 1.00e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 13 PNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNMLVRALL 92
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLA---AVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 93 VAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNVAHVL 168
Cdd:TIGR00797 78 LALLLGLPVLLVGYFFIDPLLSLMGADgevaELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINII 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 169 CSLWFAFGL--DMGIVGIAYASVIAQWTGVALSALLLFACYRRILTGIDWaEVVNLKPLRTFFIVNRDIMLRTFCIVAVY 246
Cdd:TIGR00797 158 LNYILIFGKfgFLGIVGAALATVISYWLMFLLLLYYIKKAKKIGLKWEGL-LKPDWEVLKRLLKLGLPIAFRVILESLSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 247 TFFTGASARMDePALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVSVLFVGIYIG 326
Cdd:TIGR00797 237 ALLALLVARLG-SIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILIL 315
|
330
....*....|....*...
gi 2552866260 327 WWRELVGLFVDSTAPNAA 344
Cdd:TIGR00797 316 FREFIARLFTNDPEVLEL 333
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
4-424 |
2.08e-30 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 121.87 E-value: 2.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 4 NREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTaatIGALAIGVsifnFIYWNCSFVRMGTSG----LTAQAFGAGN 79
Cdd:cd13133 4 YREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVA---LAASGPAG----VLYFAILMLFFGLSSgvqvFVAQYNGAGR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 80 FRECTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGND----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIP 155
Cdd:cd13133 77 YSRIGRVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPevqaLEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 156 MFTAITVNVAHVLCSLWFAFG----LDMGIVGIAYASVIAQWTGVALSALLLFACYRRILTGIDWAEVVNLKPLRTFFIV 231
Cdd:cd13133 157 MVANLVMVVVNIVLDYALIFGklgfPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRRFGLRRAWRFDRELLRRILRL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 232 NRDIMLRTFCIVAVYTFFTGASARMDEPALLAVNTLLLQLFTLFSYMNdGFAYAAEALTGRFIGARDEGALRDCLRRCIA 311
Cdd:cd13133 237 GLPSGLQFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMI-GLGIAVSSLVGQALGAGRPDLAMRVTRRGLK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 312 WGTAVSVLFVGIYIGWWRELVGLFvdSTAPNAATIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETR-VMRNSMFWA 390
Cdd:cd13133 316 LALAYMLLLGILFLLFPELLLSIF--TPGADFALIAELAVPLLRFVAAYILFDALALVFAGALRGAGDTRfVMLAELIVA 393
|
410 420 430
....*....|....*....|....*....|....*
gi 2552866260 391 TAAYFGIFYVGYAIIGN-NALWLAFTLYMFLRGVL 424
Cdd:cd13133 394 WLYLLPPAYLLVVLGAGlAGAWTVETVYVIVLALI 428
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
5-431 |
1.01e-27 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 114.15 E-value: 1.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIGalaIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECT 84
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAIAAVG---LATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 85 NMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGND----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAI 160
Cdd:cd13137 78 RALGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPeviaLALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 161 TVNVAHVLCSLWFAFGL----DMGIVGIAYASVIAQwtgvALSALLLFACYRRILTGIdwaevvnlKPLRTFFIVNRDIM 236
Cdd:cd13137 158 IVNVLNIVLDYVLIFGLwgfpGLGVAGAALATVISR----VVGALLLLFLLLRGRLPI--------KISFKGFRLDRKII 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 237 LRTFCI-----------VAVYTFFTGASARMDEPALLAVNtlLLQLFTLFSYM-NDGFAYAAEALTGRFIGARDEGALRD 304
Cdd:cd13137 226 KKLLRIglpagleqllrSLGFLVLLAIVASYGTAALAAYQ--IGLRIESLAFMpGFGFSMAASTLVGQNLGAGDPDEARR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 305 CLRRCIAWGTAVSVLFVGIYIGWWRELVGLFVDStapnaATIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVmr 384
Cdd:cd13137 304 YGKRALRLGVLFMGLLGLLLFIFAPPLASLFTPD-----PEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRP-- 376
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 2552866260 385 nsMFWATA----------AYFGIFYVGYAIIGnnaLWLAFTLYMFLRGVLQYFMTHR 431
Cdd:cd13137 377 --PLIINLismwlvrlplAYLLGFVLGLGLTG---IWLAMFVDTIVRAILLLYRFRK 428
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
5-423 |
1.64e-19 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 90.25 E-value: 1.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECT 84
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDLA---AVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 85 NMLVRALLVAGGMGLLMLLLQYPLGE-LALWGLNGN--DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAIT 161
Cdd:cd13131 80 RAVRQGLWLALLLSLPLMLLLWLAPPiLPLMGQEPEvaAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 162 VNVAHVLCSLWFAFGL----DMGIVGIAYASVIAQWtgVALSALLLFACYRRILTGI---DWAEVVNLKPLRTFFIVNRD 234
Cdd:cd13131 160 ALVLNIPLNYVLIFGKfglpALGGAGAGLATAIVYW--LMFLALAFYIRRHKRFRRYrlfARFWRPDWARLKELLRLGLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 235 IMLRTFCIVAVYTFFTGASARMDEPALLAVNtlLLQLFTLFSYMND-GFAYAAEALTGRFIGARDEGALRDCLRRCIAWG 313
Cdd:cd13131 238 IGLTIFFEVSLFAAVALLMGRLGTTVLAAHQ--IALNFASLLFMVPlGISMAATVRVGFALGAGDPADARRAGLVGLGLG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 314 TAVSVLFVGIYIGWWRELVGLFvdstaPNAATIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVmrnSMFWATAA 393
Cdd:cd13131 316 VGFAALTALLLLLFPEQIAGLY-----TNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYKDTRV---PFLLALIS 387
|
410 420 430
....*....|....*....|....*....|.
gi 2552866260 394 YFGI-FYVGYaiignnalWLAFTLYMFLRGV 423
Cdd:cd13131 388 YWGIgLPLGY--------LLAFTTGLGAFGV 410
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
11-425 |
6.98e-18 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 85.07 E-value: 6.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 11 ALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIG-ALAIGVSIFNFIYwncsFVRMGTSGLTAQAFGAGNFRECTNMLVR 89
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGlAFPLIALLIALGV----GLSVGTSALISQAIGAGDEEKARRVLVQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 90 ALLVAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNVA 165
Cdd:cd12082 77 SIVLAILLGLLLAALLLFFSPLILSLLGAEeeviELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 166 HVLCSLWFAFGL---DMGIVGIAYASVIAQWTGVALSALLLFACYRRILTGIDWAEvVNLKPLRTFFIVNRDIMLRTFCI 242
Cdd:cd12082 157 NILLDPLLIFGLgppELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLK-PDLELLRRLLRIGLPSAIQNSLL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 243 VAVYTFFTGASARMDEPALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVSVLFVG 322
Cdd:cd12082 236 SLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 323 IYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRV-MRNSMFWATAAYFGIFYVG 401
Cdd:cd12082 316 LILLFPEPILSLFTNDPE-----FLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKsLIVSLLSYWVVRLPLAYVL 390
|
410 420
....*....|....*....|....*
gi 2552866260 402 -YAIIGNNALWLAFTLYMFLRGVLQ 425
Cdd:cd12082 391 aYLGLGLYGIWLALVISLILAALVL 415
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
4-434 |
5.85e-17 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 82.55 E-value: 5.85e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 4 NREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIGALAIGVSIFNFIYwncSFVRMGTSGLTAQAFGAGNFREC 83
Cdd:cd13134 2 KLSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIF---SFISTGTSILIAQYLGAKDKKKA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 84 TNMLVRALLVAGGMGLLMLLLQYPLGE--LALWGLNGNDMTREYFYARIwaVPAGILLFGFNGWFTG----MQNALIPMF 157
Cdd:cd13134 79 RQIAGVALLFNLLLGLVFSLLLLFFGAelLRLMGLPPELLALGSTYLRI--VGGSLFLQALSLTLSAilrsHGRTKIPMY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 158 TAITVNVAHVLCSLWFAFGL----DMGIVGIAYASVIAQWTGVALSALLLFaCYRRILTGIDWAEVVNLKPLRTFFIVNR 233
Cdd:cd13134 157 VSLIMNILNIVGNYLLIFGWfglpKLGVAGVAISTVISRAVGLVLLFILLF-RKLKIRFRLKDLRPFPKKLLKKILKIGL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 234 DIMLRTFCIVAVYTFFTGASARMDEPALLAVNTLLLQLFTLFSYMNdGFAYAAEALTGRFIGARDEGALRDCLRRCIAWG 313
Cdd:cd13134 236 PSAGEELSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSL-AIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 314 TAVSVLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRV-MRNSMF--WA 390
Cdd:cd13134 315 LLVSLAVALLLALFREPILGLFTDDPE-----IIALGKTLLLISILLEPGRAFNIVLIGSLRAAGDARFpVLIGIIsmWG 389
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 2552866260 391 TA---AYFGIFYVGYAIIGnnaLWLAFTLYMFLRGVlqyFMTHRLRS 434
Cdd:cd13134 390 ISvplAYLLGIVLGLGLLG---VWIAFAADEWVRGI---IMLWRWRS 430
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
7-433 |
4.71e-16 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 79.81 E-value: 4.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 7 ILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFREC--- 83
Cdd:cd13138 5 LLLFALPLLLSNLLQQLYNLVDLLIVGQFLGVAA--LAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAkka 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 84 -TNMLVRALLVAGGMGLLMLLLQYPLgeLALWGLNGN--DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAI 160
Cdd:cd13138 83 vGTLLVLFLILGIVLTILGLLFAPPI--LRLMNTPAEilELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 161 TVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQwtgvALSALLLFACYRRiltgidwaEVVNLKPLRTFFIVNRDIMLRTF 240
Cdd:cd13138 161 IACVLNIILDLLFIAVFHMGVAGAALATVIAQ----AISVLLALYYLRK--------KKLPFKLSLKDFRFDKEILKEIL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 241 ----------CIVAV-YTFFTGASARMDEPALLAVNTLLLQLFTLFSYMNdGFAYAAEALTGRFIGARDEGALRDCLRRC 309
Cdd:cd13138 229 kiglpsalqqSLVSIsFLIINSIVNSYGVVASAAYGIANKINSFAFLPPS-AIGQAVSTFVAQNIGAGKIERAKKGLRTG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 310 IAWGTAVSVLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIPVASAMPFIMDGIMVGATETRVmrnSMFW 389
Cdd:cd13138 308 IIISLIIGLIIILLVFFFAPQLLGLFTSDPE-----VIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKF---PMII 379
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 2552866260 390 ATAAYFGI------FYVGYAIIGNNALWLAFTLYMFLRGVLQYFMTHRLR 433
Cdd:cd13138 380 SILRLWLVriplayLLSRLTGLGLFGIWLAMPISNILSAIICIIYYRKGR 429
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
13-167 |
2.38e-11 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 61.81 E-value: 2.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 13 PNIVSNITVPLMGIVSTAIAGHWGSDTaatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNMLVRALL 92
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVA---LAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLI 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2552866260 93 VAGGMGLLMLLLQYPLGELALWGLNGND----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITVNVAHV 167
Cdd:pfam01554 78 LGLLLSLPIALLVLLFSEPILSLFGQDEevlaLAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNI 156
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
7-340 |
5.06e-10 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 60.99 E-value: 5.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 7 ILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFREC--- 83
Cdd:cd13143 6 FLKFALPAIIGMLVNGLYNIVDGIFVGHGVGALA--LAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKAnri 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 84 -TNMLVRALLVAGGMGLLMLLLQYPLgeLALWGLNGN--DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAI 160
Cdd:cd13143 84 fSTALLLSLILGLLLTILGLLFLDPL--LRLLGASGEllPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGML 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 161 TVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQwtgvALSALLLFACYRRILTgidwaevvNLKPLRTFFIVNRDIMLRTF 240
Cdd:cd13143 162 IGAVLNIILDPLFIFVLGLGIAGAALATVIAQ----LISLLLLLLYFFRGKS--------LLKLSLLRFKLSLKIIKEIL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 241 civavytfFTGASARMDEPALLAVNTLLLQLFTLFSYMND-------------------GFAYAAEALTGRFIGARDEGA 301
Cdd:cd13143 230 --------ALGFPSFLMQLSSSVVTIVLNLTLLGYGGDIGvaafgivtriltflflpliGLSQGLQPIIGYNYGAGNYDR 301
|
330 340 350
....*....|....*....|....*....|....*....
gi 2552866260 302 LRDCLRRCIAWGTAVSVLFVGIYIGWWRELVGLFVDSTA 340
Cdd:cd13143 302 VKQALKLALIVALIYGLVLFLILLLFPEQIVSLFTDDPE 340
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
1-427 |
1.95e-07 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 52.91 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 1 MNMNREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIGALAIgvsIFNFIYWNCSFVRMGTSGLTAQAFGAGNF 80
Cdd:cd13140 1 GPILKTLLRLALPIMGTSFIQMAYNLTDMFWVGRLGSDAVAAVGTAGF---FVWLAYALALLSKIGAQVKVSQSIGAKDE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 81 RECTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGND-----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIP 155
Cdd:cd13140 78 KEARKYARNALQLNLLLGILYGLLLLLFAKPLIGFFNLGDaevisLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 156 M-FTAITVNVAHVLCSLwFAFGLD----MGIVGIAYASVIAQWTGValsalLLFACYRRILTGIDWAEVVNLKPLRTFFi 230
Cdd:cd13140 158 FiINAIGLVLNIILDPL-LIFGFGpfpaLGVAGAALATVLAQAIVF-----LLFLYALKKKKGLFLKIRILKRPDRKYI- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 231 vnRDIMLRTFCIVAVYTFFTGAS---ARMDE---PALLAVNTLLLQLFTLFSYMNDGFAYAAEALTGRFIGARDEGALRD 304
Cdd:cd13140 231 --KEILKLGLPVALQSILFALISmilARIIAsfgPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 305 CLRRCIAWGTAVSVLFVGIYIGWWRELVGLFVdstaPNAATIvELAGEYIVWIILIPVASAMPFIMDGIMVGATETR-VM 383
Cdd:cd13140 309 GYKTALKIASAIGLFATLLLFFFGEPLFSLFI----PDPETI-AIGVDYLRILGFSQLFMCLEITTTGAFNGLGRTKpPA 383
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2552866260 384 RNSMFWATAAYFGIFYVGYAIIGNNALWLAFTLYMFLRGVLQYF 427
Cdd:cd13140 384 IISIVFNGLRIPLALLLSPTGLGLNGIWWAISISSILKGIILTI 427
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
5-376 |
1.96e-07 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 53.06 E-value: 1.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIGALAigvSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECT 84
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVGNVT---TPFNTITGFLGSISIGFTILGSQSVGAKDIKRIN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 85 N----MLVRALLVAGGMGLLMLLLQYPLgeLALWGLNGNDMTREYFYARIWAVPAGILLFG--FNGWFTGMQNALIPMFT 158
Cdd:cd13135 78 DyaisSIVYNSIIGVILFLLWLFGARII--FVLFGVDGQILGYSINYVRIFSIYLLLLGILftFSSILQGIGETKPIMYG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 159 AITVNVAHVLCSLWFAFGL----DMGIVGIAYASVIAQWTGVALSALLLFAcYRRILTGI--DWAEVVNLKPLRTFFIVN 232
Cdd:cd13135 156 GIIKNLLNVILDYVLIFGNfgfpRLGIIGAAIATTIANVLNLIILVYLCRK-IKKLTFKLsnTKVLKANIRPYKFTIKLG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 233 RDIMLRTFCIVAVYTFFTGASARMDEPALLAVNTLLLQLFTLFSYMNdGFAYAAEALTGRFIGARDEGALRDCLRRCIAW 312
Cdd:cd13135 235 LPLGGEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMY-GYSSAALTLVGESIGKKDLKEALRIGNICLGL 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552866260 313 GTAVSVLFVGIYIGWWRELVGLFVDSTApnaatIVELAGEYIVWIILIpvasaMPFIMDGIMVG 376
Cdd:cd13135 314 GLLIYIAAAIVFLAFPYKILSLFTNDPE-----LINYSIPYLIFIIII-----LFFKSINIVYG 367
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
5-209 |
1.99e-07 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 52.96 E-value: 1.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFiywNCSFVRMGTSG----LTAQAFGAGNF 80
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELA---AASLASSFANV---TGFSILLGLASaldtLCGQAFGAKNY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 81 RECTNMLVRALLVAGGMGLlmlllqyPLGelALWgLNGNDM-------------TREYFYARIWAVPAGILLFGFNGWFT 147
Cdd:cd13132 77 KLVGVYLQRALVILLLCCV-------PIS--LLW-LNTEPIllllgqdpeiarlAGEYLRWLIPGLFAYALFEPLKRYLQ 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2552866260 148 GMQNALIPMFTAITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALsaLLLFACYRR 209
Cdd:cd13132 147 AQGIVLPLVYISLVALLLNILLNYLLVFVLGLGFIGAALATSISYWLIVVL--LLLYIFFSK 206
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
5-210 |
2.88e-06 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 49.38 E-value: 2.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECT 84
Cdd:cd13138 225 KEILKIGLPSALQQSLVSISFLIINSIVNSYGVVASA---AYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAK 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 85 NMLVRALLVAGGMGLLMLLLQYPLGELALwGLNGND-----MTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMF-T 158
Cdd:cd13138 302 KGLRTGIIISLIIGLIIILLVFFFAPQLL-GLFTSDpevieIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIiS 380
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2552866260 159 AITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAqwtgVALSALLLFACYRRI 210
Cdd:cd13138 381 ILRLWLVRIPLAYLLSRLTGLGLFGIWLAMPIS----NILSAIICIIYYRKG 428
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
5-204 |
3.15e-05 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 46.16 E-value: 3.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAatIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECT 84
Cdd:cd12082 219 RRLLRIGLPSAIQNSLLSLGLLIIVAIVAAFGGAAA--LAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRAR 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 85 NMLVRALLVAGGMGLLMLLLQYPLGELALW----GLNGNDMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAI 160
Cdd:cd12082 297 RITWVALLIGLLIGAVLGLLILLFPEPILSlftnDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSL 376
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2552866260 161 TVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVALSALLLF 204
Cdd:cd12082 377 LSYWVVRLPLAYVLAYLGLGLYGIWLALVISLILAALVLLLFFR 420
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
1-204 |
3.41e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 46.07 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 1 MNMNREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIGalaIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNF 80
Cdd:cd13139 10 GSLNRAIFLLAIPMVLEMVMESLFAVVDLYFVSRLGALAIATVG---LTESVLTIVYSIAIGLSMAATALVARRIGEKDP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 81 RECTNMLVRALLVAGGMGLLMLLLQYPLGE--LALWGLNGNDMTREYFYARIW--AVPAGILLFGFNGWFTGMQNALIPM 156
Cdd:cd13139 87 EGAGFAAVQAILLGVALSLILSILGYFFAEdiLSLMGASPAVIAEGYGYTRIMfgGNGFIMLLFLINGIFRGAGDAAIAM 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2552866260 157 FTAITVNVAH-VLCSLwFAFGL----DMGIVGIAYASVIAQWTGVALSALLLF 204
Cdd:cd13139 167 RSLWLANGLNiILDPL-FIFGLgpipAMGVTGAAIATTIGRSIGVLYQLYHLF 218
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
5-222 |
3.46e-05 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 45.96 E-value: 3.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 5 REILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECT 84
Cdd:PRK01766 12 RQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDLA---AVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERIA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 85 NMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPM---F 157
Cdd:PRK01766 89 HQVRQGLWLALFLSVLIMLVLYNAVPPILNMMNLEpevaDIAVGYLHALLWGIPAYLLYQVLRSFIDGLGKTKPTMvigF 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2552866260 158 TAITVNVAHVLCSLWFAFGL-DMGIVGIAYASVIAQWTGVALSALLL-----FACYR--RILTGIDWAEVVNL 222
Cdd:PRK01766 169 LGLLINIPLNYIFIYGKFGFpELGGVGCGVATAIVYWVMFLAMLIYIkrarrFRDFRlfKGLYKPDWAVIKRL 241
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
7-197 |
7.90e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 44.70 E-value: 7.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 7 ILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAATIGALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRECTNM 86
Cdd:cd13146 10 LIRLALPILIGQLFQLLYNITDTIWISMIDPSDPALVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGAQRAKELDQA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 87 LVRALLVAGGMGLLMLLLQYPLGE--LALWGLNGNDMTR--EYFYARIWAVPAGILLFGFNGWFTGMQNALIPMFTAITV 162
Cdd:cd13146 90 ADSGLALALLAATVIVVLGYIFAEplLQLLGAKGLLLEYalEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMMAMLIG 169
|
170 180 190
....*....|....*....|....*....|....*
gi 2552866260 163 NVAHVLCSLWFAFGLDMGIVGIAYASVIAQWTGVA 197
Cdd:cd13146 170 TVVNIVLDPILIFVFDMGVKGAALATVLAQAISLL 204
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
1-209 |
2.83e-04 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 42.88 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 1 MNMNREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNF 80
Cdd:cd13137 222 RKIIKKLLRIGLPAGLEQLLRSLGFLVLLAIVASYGTAALA---AYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDP 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 81 RECTNMLVRALLVAGGMGLLMLLLQYPLGELALWGLNGN----DMTREYFYARIWAVPAGILLFGFNGWFTGMQNALIPM 156
Cdd:cd13137 299 DEARRYGKRALRLGVLFMGLLGLLLFIFAPPLASLFTPDpeviELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPL 378
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2552866260 157 F-TAITVNVAHVLCSLWFAFGLDMGIVGIAYASVIAQwtgvALSALLLFACYRR 209
Cdd:cd13137 379 IiNLISMWLVRLPLAYLLGFVLGLGLTGIWLAMFVDT----IVRAILLLYRFRK 428
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
281-382 |
9.64e-04 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 39.86 E-value: 9.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 281 GFAYAAEALTGRFIGARDEGALRDCLRRCIAWGTAVSVLFVGIYIGWWRELVGLFVDStapnaATIVELAGEYIVWIILI 360
Cdd:pfam01554 47 GLGTALTTLVGQALGAGNFKRAGVALRQGLILGLLLSLPIALLVLLFSEPILSLFGQD-----EEVLALAKRYLRILILG 121
|
90 100
....*....|....*....|..
gi 2552866260 361 PVASAMPFIMDGIMVGATETRV 382
Cdd:pfam01554 122 IPFYALQFVLSGFLRGQGDTKP 143
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
3-197 |
1.39e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 40.66 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 3 MNREILRIALPNIVSNITVPLMGIVSTAIAGHWGSDTAAtigALAIGVSIFNFIYWNCSFVRMGTSGLTAQAFGAGNFRE 82
Cdd:cd13145 7 IPKLIRKLAIPASVGFFFNTMFNVVDTFFAGKISTEALA---ALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552866260 83 ----CTNMLVRALLVAGGMGLLMLLLQYPLgeLALWGLNGN--DMTREYFYARIWAVPAGILLFGFNGWFTG------MQ 150
Cdd:cd13145 84 arryAAQGLSFGIILAILLTVIGLFAAPPL--FRLLGAEGDylDLALEYMDVIFAGSIFFLLNFGLNGILNAqgdtksYR 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2552866260 151 NALIPMFtaitvnVAHVLCSLWFAFG----LDMGIVGIAYASVIAQWTGVA 197
Cdd:cd13145 162 NFLIIGF------FLNIILDPLFIFGgggiPAMGVSGIALATIISQFIGMF 206
|
|
| |
