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Conserved domains on  [gi|2698138749|ref|WP_336620743|]
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alpha/beta fold hydrolase, partial [Bifidobacterium dentium]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 57-104 8.91e-06

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member pfam00561:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 245  Bit Score: 42.49  E-value: 8.91e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2698138749  57 PLLIFLQGGPGGegprlnsptSDGWIEE----ATKHFRVILPDQRGAGRSSR 104
Cdd:pfam00561   1 PPVLLLHGLPGS---------SDLWRKLapalARDGFRVIALDLRGFGKSSR 43
 
Name Accession Description Interval E-value
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 57-104 8.91e-06

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 42.49  E-value: 8.91e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2698138749  57 PLLIFLQGGPGGegprlnsptSDGWIEE----ATKHFRVILPDQRGAGRSSR 104
Cdd:pfam00561   1 PPVLLLHGLPGS---------SDLWRKLapalARDGFRVIALDLRGFGKSSR 43
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 39-104 8.28e-05

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 39.60  E-value: 8.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2698138749  39 IKLFYRVVTtpehvhDDLPLLIFLQGGPGgegprlnspTSDGW---IEEATKHFRVILPDQRGAGRSSR 104
Cdd:COG0596    12 VRLHYREAG------PDGPPVVLLHGLPG---------SSYEWrplIPALAAGYRVIAPDLRGHGRSDK 65
 
Name Accession Description Interval E-value
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 57-104 8.91e-06

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 42.49  E-value: 8.91e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2698138749  57 PLLIFLQGGPGGegprlnsptSDGWIEE----ATKHFRVILPDQRGAGRSSR 104
Cdd:pfam00561   1 PPVLLLHGLPGS---------SDLWRKLapalARDGFRVIALDLRGFGKSSR 43
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 39-104 8.28e-05

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 39.60  E-value: 8.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2698138749  39 IKLFYRVVTtpehvhDDLPLLIFLQGGPGgegprlnspTSDGW---IEEATKHFRVILPDQRGAGRSSR 104
Cdd:COG0596    12 VRLHYREAG------PDGPPVVLLHGLPG---------SSYEWrplIPALAAGYRVIAPDLRGHGRSDK 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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