|
Name |
Accession |
Description |
Interval |
E-value |
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-209 |
2.58e-104 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 300.93 E-value: 2.58e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGS----HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQ 77
Cdd:cd03293 1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPDRGYVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:cd03293 81 QDALLPWLTVLDNVALGLElQGVPKAEARERaeelLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFS 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG-CNIISQYEI 209
Cdd:cd03293 161 ALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSARpGRIVAEVEV 218
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-243 |
3.32e-103 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 299.70 E-value: 3.32e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF----GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLF 76
Cdd:COG1116 7 ALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPDRGVVF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:COG1116 87 QEPALLPWLTVLDNVALGLElRGVPKAERRERarelLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEPF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 152 GALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG-CNIISQYEITASHPRS---RNDSHLLKIRN 227
Cdd:COG1116 167 GALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSARpGRIVEEIDVDLPRPRDrelRTSPEFAALRA 246
|
250
....*....|....*.
gi 2756312332 228 EIMEtfALNHHQVEPE 243
Cdd:COG1116 247 EILD--LLREEAERAA 260
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-206 |
1.06e-72 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 220.47 E-value: 1.06e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQH 78
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPerrNIGMVFQD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGF-QQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:cd03259 81 YALFPHLTVAENIAFGLkLRGVPKAEIRARvrelLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 154 LDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCniISQ 206
Cdd:cd03259 161 LDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGR--IVQ 211
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-217 |
1.27e-72 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 225.36 E-value: 1.27e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPS--PDCLMLFQ 77
Cdd:COG3842 5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRdVTGLPPekRNVGMVFQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIriGF---QQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:COG3842 85 DYALFPHLTVAENV--AFglrMRGVPKAEIRARvaelLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 151 LGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCniISQ----YEItASHPRSR 217
Cdd:COG3842 163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGR--IEQvgtpEEI-YERPATR 230
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-197 |
3.83e-70 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 215.88 E-value: 3.83e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHK----VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLF 76
Cdd:COG4525 3 MLTVRHVSVRYPGGGqpqpALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADRGVVF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:COG4525 83 QKDALLPWLNVLDNVAFGLRlRGVPKAERRARaeelLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPF 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 152 GALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:COG4525 163 GALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVM 208
|
|
| ABC_ATP_SaoA |
NF040729 |
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ... |
2-230 |
3.25e-67 |
|
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC transporter in which both the permease subunit SaoP, and the substrate-binding protein SaoB, are nearly always selenoproteins that were unrecognized as such until recently (2022). The SAO system is found in Clostridium difficile and various other anaerobic heterotrophs.
Pssm-ID: 468693 [Multi-domain] Cd Length: 248 Bit Score: 208.06 E-value: 3.25e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGS----HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQ 77
Cdd:NF040729 2 LKIQNISKTFINnkkeNEVLKDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNATSGEILVNGNEVTKPGPDRGFVFQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIRIGF-QQKISDEE----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:NF040729 82 NYALFPWMTVKENIEYPMkQQKMPKQErekrLNELLEMAQLTGKENLYPHQISGGMKQRTAVIRALACKPEVLLMDEPLG 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDR-IVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIM 230
Cdd:NF040729 162 AVDFQMRQILQEELESIWLKDKTTVLMVTHDVDEAVYLSDRvIVMSRDKGKILEDLKIDLPRPRNRESEKYLEYKDHLT 240
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
17-230 |
1.11e-66 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 206.16 E-value: 1.11e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNI----- 91
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMVVFQNYSLLPWLTVRENIalavd 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 92 ------RIGFQQKISDEEINaqlkLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQ 165
Cdd:TIGR01184 81 rvlpdlSKSERRAIVEEHIA----LVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEE 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 166 LVQLKHKTESTIILVAHDIDEAIYLSDRIVLL--GEGCNIISQYEITASHPRSR----NDSHLLKIRNEIM 230
Cdd:TIGR01184 157 LMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLtnGPAANIGQILEVPFPRPRDRlevvEDPSYYDLRNEAL 227
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-200 |
7.76e-64 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 202.61 E-value: 7.76e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQ 77
Cdd:COG3839 3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPkdrNIAMVFQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIriGF---QQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:COG3839 83 SYALYPHMTVYENI--AFplkLRKVPKAEIDRRvreaAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 151 LGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG3839 161 LSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDG 210
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-217 |
4.71e-63 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 200.37 E-value: 4.71e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE--IKQQPSPD--CLMLFQ 77
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRdlFTNLPPRErrVGFVFQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIRIGFQ-QKISDEEINA----QLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:COG1118 83 HYALFPHMTVAENIAFGLRvRPPSKAEIRArveeLLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFG 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCniISQ-------YEitasHPRSR 217
Cdd:COG1118 163 ALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGR--IEQvgtpdevYD----RPATP 228
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-200 |
5.32e-62 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 194.92 E-value: 5.32e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHN 80
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAERGVVFQNEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWKTINDNIRIGFQ----QKISDEEINAQ-LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:PRK11248 81 LLPWRNVQDNVAFGLQlagvEKMQRLEIAHQmLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2756312332 156 AFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11248 161 AFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-200 |
2.78e-61 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 190.48 E-value: 2.78e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-------M 74
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPplrrrigM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIGfqqkisdeeinaqlklvdlegrgkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGAL 154
Cdd:cd03229 81 VFQDFALFPHLTVLENIALG-----------------------------LSGGQQQRVALARALAMDPDVLLLDEPTSAL 131
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 155 DAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03229 132 DPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-200 |
3.49e-60 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 189.37 E-value: 3.49e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPD--CLMLFQH 78
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGkDITNLPPHKrpVNTVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGFQ-QKISDEEINA----QLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:cd03300 81 YALFPHLTVFENIAFGLRlKKLPKAEIKErvaeALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2756312332 154 LDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03300 161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKG 207
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-200 |
2.00e-59 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 186.93 E-value: 2.00e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGS----HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL---- 73
Cdd:cd03255 1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELaafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -----MLFQHHNLLPWKTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:cd03255 81 rrhigFVFQSFNLLPDLTALENVELPLLlAGVPKKERRERaeelLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDG 216
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-200 |
1.11e-58 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 185.25 E-value: 1.11e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGS----HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCLML 75
Cdd:COG1136 4 LLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGqDISSLSERELARL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 --------FQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKP 142
Cdd:COG1136 84 rrrhigfvFQFFNLLPELTALENVALplllaGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDiDEAIYLSDRIVLLGEG 200
Cdd:COG1136 164 KLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDG 220
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-207 |
1.58e-58 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 187.61 E-value: 1.58e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPsPDCL----- 73
Cdd:COG1125 1 MIEFENVTKRYpDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEdIRDLD-PVELrrrig 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 --MlfQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGR--GKHFPEQLSGGMKQRVALCRAHVHKPNV 144
Cdd:COG1125 80 yvI--QQIGLFPHMTVAENIATvprllGWDKERIRARVDELLELVGLDPEeyRDRYPHELSGGQQQRVGVARALAADPPI 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcnIISQY 207
Cdd:COG1125 158 LLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREG--RIVQY 218
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-206 |
2.63e-58 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 184.00 E-value: 2.63e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQH 78
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPkdrDIAMVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGFQQKISDE-EINAQL----KLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:cd03301 81 YALYPHMTVYDNIAFGLKLRKVPKdEIDERVrevaELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSN 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 154 LDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcnIISQ 206
Cdd:cd03301 161 LDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDG--QIQQ 211
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-231 |
6.78e-58 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 184.50 E-value: 6.78e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 4 IQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLP 83
Cdd:PRK11247 15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREDTRLMFQDARLLP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 84 WKTINDNIRIGFQQKISDEEINAqLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLR 163
Cdd:PRK11247 95 WKKVIDNVGLGLKGQWRDAALQA-LAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQ 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 164 DQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQYEITASHPRSRNDSHLLKIRNEIME 231
Cdd:PRK11247 174 DLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEG-KIGLDLTVDLPRPRRRGSARLAELEAEVLQ 240
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-200 |
1.56e-56 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 184.38 E-value: 1.56e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSP--DCLMLFQH 78
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQdITHVPAEnrHVNTVFQS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:PRK09452 95 YALFPHMTVFENVAFGLRmQKTPAAEITPRvmeaLRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSA 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 154 LDaftrYKLRDQ----LVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK09452 175 LD----YKLRKQmqneLKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDG 221
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-200 |
2.13e-55 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 177.53 E-value: 2.13e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQH 78
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVqerNVGFVFQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGFQ-----QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:cd03296 83 YALFRHMTVFDNVAFGLRvkprsERPPEAEIRAKvhelLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDE 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03296 163 PFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKG 213
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-200 |
6.61e-55 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 176.32 E-value: 6.61e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL------- 73
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELyelrrri 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -MLFQHHNLLPWKTINDNIRIGFQQ--KISDEEI----NAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVIL 146
Cdd:COG1127 85 gMLFQGGALFDSLTVFENVAFPLREhtDLSEAEIrelvLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 147 MDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1127 165 YDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADG 218
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
17-200 |
9.19e-55 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 176.68 E-value: 9.19e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL---------MLFQHHNLLPWKTI 87
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELrelrrkkisMVFQSFALLPHRTV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 NDNIRIGFQ-QKISDEEINA----QLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:cd03294 120 LENVAFGLEvQGVPRAEREEraaeALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREM 199
|
170 180 190
....*....|....*....|....*....|....*...
gi 2756312332 163 RDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03294 200 QDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDG 237
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
12-200 |
1.72e-54 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 175.18 E-value: 1.72e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPsPDCL-----MLFQHHNLLPWK 85
Cdd:cd03295 12 GGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEdIREQD-PVELrrkigYVIQQIGLFPHM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINDNIRI-----GFQQKISDEEINAQLKLVDLE--GRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:cd03295 91 TVEENIALvpkllKWPKEKIRERADELLALVGLDpaEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPIT 170
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 159 RYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03295 171 RDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNG 212
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-200 |
1.48e-53 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 172.63 E-value: 1.48e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVihNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE------IKQQP-Spdcl 73
Cdd:COG3840 1 MLRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQdltalpPAERPvS---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIRIGFQQ--KISDEE---INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:COG3840 75 MLFQENNLFPHLTVAQNIGLGLRPglKLTAEQraqVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLD 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG3840 155 EPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADG 206
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-200 |
2.10e-52 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 169.47 E-value: 2.10e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID--------NEIKQQPSpdcl 73
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLgedvardpAEVRRRIG---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:COG1131 77 YVPQEPALYPDLTVRENLRFfarlyGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLKHKtESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1131 157 EPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKG 207
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
17-200 |
2.62e-52 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 173.75 E-value: 2.62e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL---------MLFQHHNLLPWKTI 87
Cdd:COG4175 43 VNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDITKLSKKELrelrrkkmsMVFQHFALLPHRTV 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 NDNIRIGFQ-QKISDEEINA----QLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:COG4175 123 LENVAFGLEiQGVPKAERRErareALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREM 202
|
170 180 190
....*....|....*....|....*....|....*...
gi 2756312332 163 RDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4175 203 QDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDG 240
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
11-200 |
4.32e-52 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 172.60 E-value: 4.32e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE------IKQQpspDCLMLFQHHNLLPW 84
Cdd:PRK11432 16 FGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEdvthrsIQQR---DICMVFQSYALFPH 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:PRK11432 93 MSLGENVGYGLKmLGVPKEERKQRvkeaLELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 160 YKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11432 173 RSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKG 213
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-218 |
3.10e-50 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 164.21 E-value: 3.10e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-------- 73
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELyrlrrrmg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIriGF----QQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:cd03261 81 MLFQSGALFDSLTVFENV--AFplreHTRLSEEEIREIvlekLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 146 LMDEPLGALDAFTRYKLrDQLVQ-LKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQY---EITAS-HPRSRN 218
Cdd:cd03261 159 LYDEPTAGLDPIASGVI-DDLIRsLKKELGLTSIMVTHDLDTAFAIADRIAVLYDG-KIVAEGtpeELRASdDPLVRQ 234
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-200 |
2.10e-47 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 154.86 E-value: 2.10e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLM----LFQ 77
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRrigyLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIRigfqqkisdeeinaqlklvdlegrgkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAF 157
Cdd:cd03230 81 EPSLYENLTVRENLK-------------------------------LSGGMKQRLALAQALLHDPELLILDEPTSGLDPE 129
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 158 TRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03230 130 SRREFWELLRELK-KEGKTILLSSHILEEAERLCDRVAILNNG 171
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-200 |
7.68e-47 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 154.61 E-value: 7.68e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-------M 74
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINelrqkvgM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIGFQ--QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:cd03262 81 VFQQFNLFPHLTVLENITLAPIkvKGMSKAEAEERalelLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLKHkTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03262 161 EPTSALDPELVGEVLDVMKDLAE-EGMTMVVVTHEMGFAREVADRVIFMDDG 211
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-200 |
1.33e-46 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 155.02 E-value: 1.33e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL----MLF 76
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARrqigVLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIR-IGFQQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:COG4555 81 DERGLYDRLTVRENIRyFAELYGLFDEELKKRieelIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPT 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 152 GALDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4555 161 NGLDVMARRLLREILRALK-KEGKTVLFSSHIMQEVEALCDRVVILHKG 208
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-200 |
3.34e-46 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 153.64 E-value: 3.34e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDCL----ML 75
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKdITKKNLRELRrkvgLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHhnllPW-----KTINDNIRIG-FQQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:COG1122 81 FQN----PDdqlfaPTVEEDVAFGpENLGLPREEIRERveeaLELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 146 LMDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1122 157 VLDEPTAGLDPRGRRELLELLKRL-NKEGKTVIIVTHDLDLVAELADRVIVLDDG 210
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-200 |
7.45e-46 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 152.84 E-value: 7.45e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL------- 73
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINklrrkvg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIRIGFQ--QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILM 147
Cdd:COG1126 81 MVFQQFNLFPHLTVLENVTLAPIkvKKMSKAEAEERamelLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLF 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 148 DEPLGALDAftryklrdQLV--------QLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1126 161 DEPTSALDP--------ELVgevldvmrDLA-KEGMTMVVVTHEMGFAREVADRVVFMDGG 212
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
12-200 |
1.63e-45 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 151.08 E-value: 1.63e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCL----MLFQH--HNLLPw 84
Cdd:cd03225 12 GARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGkDLTKLSLKELRrkvgLVFQNpdDQFFG- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGF-QQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:cd03225 91 PTVEEEVAFGLeNLGLPEEEIEERveeaLELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGR 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 160 YKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03225 171 RELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDG 210
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-217 |
6.02e-45 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 154.61 E-value: 6.02e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQ 77
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPyqrPINMMFQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIRIGFQQ-KISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK11607 99 SYALFPHMTVEQNIAFGLKQdKLPKAEIASRvnemLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMG 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNI-ISQYEITASHPRSR 217
Cdd:PRK11607 179 ALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVqIGEPEEIYEHPTTR 244
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-200 |
1.42e-44 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 149.25 E-value: 1.42e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIH-----PSSGRVIIDNEIKQQPSPDCL--- 73
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDIYDLDVDVLelr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ----MLFQHHNLLPwKTINDNIRIGFQ------QKISDEEINAQLKLVDLEGRGKH--FPEQLSGGMKQRVALCRAHVHK 141
Cdd:cd03260 81 rrvgMVFQKPNPFP-GSIYDNVAYGLRlhgiklKEELDERVEEALRKAALWDEVKDrlHALGLSGGQQQRLCLARALANE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 142 PNVILMDEPLGALDAFTRYKLRDQLVQLKHKTesTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03260 160 PEVLLLDEPTSALDPISTAKIEELIAELKKEY--TIVIVTHNMQQAARVADRTAFLLNG 216
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-201 |
1.83e-44 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 149.19 E-value: 1.83e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF----GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL--- 73
Cdd:cd03257 1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRkir 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -----MLFQH--HNLLPWKTINDNIR--IGFQQKISDEEINAQLKLVDLEGRG------KHFPEQLSGGMKQRVALCRAH 138
Cdd:cd03257 81 rkeiqMVFQDpmSSLNPRMTIGEQIAepLRIHGKLSKKEARKEAVLLLLVGVGlpeevlNRYPHELSGGQRQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGC 201
Cdd:cd03257 161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGK 223
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-206 |
3.41e-44 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 151.77 E-value: 3.41e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII-DNEIKQQPSPD--CLMLFQH 78
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFhGTDVSRLHARDrkVGFVFQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGF-----QQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK10851 83 YALFRHMTVFDNIAFGLtvlprRERPNAAAIKAKvtqlLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDE 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCniISQ 206
Cdd:PRK10851 163 PFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGN--IEQ 217
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-219 |
6.33e-44 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 148.41 E-value: 6.33e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGS----HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-----D 71
Cdd:COG1124 1 MLEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRkafrrR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CLMLFQH-----HnllPWKTINDNIR-----IGFQQkiSDEEINAQLKLVDLEGRGKH-FPEQLSGGMKQRVALCRAHVH 140
Cdd:COG1124 81 VQMVFQDpyaslH---PRHTVDRILAeplriHGLPD--REERIAELLEQVGLPPSFLDrYPHQLSGGQRQRVAIARALIL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 141 KPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCnIISQYEITASHPRSRND 219
Cdd:COG1124 156 EPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGR-IVEELTVADLLAGPKHP 233
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-200 |
1.69e-43 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 144.31 E-value: 1.69e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 3 KIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNeikqqpspdclmlfqhhnll 82
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDG-------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 83 pwKTINDNIRIGFQQKISdeeinaqlkLVDlegrgkhfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:cd00267 61 --KDIAKLPLEELRRRIG---------YVP----------QLSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERL 119
|
170 180 190
....*....|....*....|....*....|....*...
gi 2756312332 163 RDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd00267 120 LELLREL-AEEGRTVIIVTHDPELAELAADRVIVLKDG 156
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-200 |
3.98e-43 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 152.36 E-value: 3.98e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSH-----KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDCL- 73
Cdd:COG1123 260 LLEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKdLTKLSRRSLRe 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ------MLFQH--HNLLPWKTINDNIR--IGFQQKISDEEINAQ----LKLVDLEGRGKH-FPEQLSGGMKQRVALCRAH 138
Cdd:COG1123 340 lrrrvqMVFQDpySSLNPRMTVGDIIAepLRLHGLLSRAERRERvaelLERVGLPPDLADrYPHELSGGQRQRVAIARAL 419
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1123 420 ALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDG 481
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-200 |
4.75e-43 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 145.42 E-value: 4.75e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQL----QHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL--- 73
Cdd:cd03258 1 MIELKNVskvfGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELrka 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -----MLFQHHNLLPWKTINDNI----RIGFQQKIS-DEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:cd03258 81 rrrigMIFQHFNLLSSRTVFENValplEIAGVPKAEiEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03258 161 VLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKG 217
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-185 |
6.38e-43 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 144.81 E-value: 6.38e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCLML--- 75
Cdd:COG2884 1 MIRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGqDLSRLKRREIPYLrrr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 ----FQHHNLLPWKTINDNIR-----IGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVIL 146
Cdd:COG2884 81 igvvFQDFRLLPDRTVYENVAlplrvTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLL 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 2756312332 147 MDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDID 185
Cdd:COG2884 161 ADEPTGNLDPETSWEIMELLEEI-NRRGTTVLIATHDLE 198
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
4-183 |
4.17e-41 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 139.67 E-value: 4.17e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 4 IQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLM--------- 74
Cdd:TIGR03608 1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASkfrreklgy 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIGFQ-QKIS----DEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:TIGR03608 81 LFQNFALIENETVEENLDLGLKyKKLSkkekREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160
|
170 180 190
....*....|....*....|....*....|....
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKhKTESTIILVAHD 183
Cdd:TIGR03608 161 PTGSLDPKNRDEVLDLLLELN-DEGKTIIIVTHD 193
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-200 |
1.02e-40 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 140.18 E-value: 1.02e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDcL-----M 74
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGrDLASLSRRE-LarriaY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNL--------------LPWktindnirIGFQQKISDEE---INAQLKLVDLEG-RGKHFPEqLSGGMKQRVALCR 136
Cdd:COG1120 80 VPQEPPApfgltvrelvalgrYPH--------LGLFGRPSAEDreaVEEALERTGLEHlADRPVDE-LSGGERQRVLIAR 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 137 AHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1120 151 ALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDG 214
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
20-200 |
4.76e-40 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 137.24 E-value: 4.76e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPD--CLMLFQHHNLLPWKTINDNIRIGFQ 96
Cdd:cd03298 17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGvDVTAAPPADrpVSMLFQENNLFAHLTVEQNVGLGLS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 97 QKI-----SDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKH 171
Cdd:cd03298 97 PGLkltaeDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLHA 176
|
170 180
....*....|....*....|....*....
gi 2756312332 172 KTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03298 177 ETKMTVLMVTHQPEDAKRLAQRVVFLDNG 205
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
2-200 |
6.68e-40 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 136.87 E-value: 6.68e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPD----CLMLF 76
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKpLSAMPPPEwrrqVAYVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPwKTINDNIRIGFQ---QKISDEEINAQLKLVDLEGRGKHFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:COG4619 81 QEPALWG-GTVRDNLPFPFQlreRKFDRERALELLERLGLPPDILDKPvERLSGGERQRLALIRALLLQPDVLLLDEPTS 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4619 160 ALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAG 207
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-200 |
7.16e-40 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 145.75 E-value: 7.16e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHK--VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQpSPDCL----- 73
Cdd:COG2274 474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGiDLRQI-DPASLrrqig 552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPwKTINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKP 142
Cdd:COG2274 553 VVLQDVFLFS-GTIRENITLG-DPDATDEEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARALLRNP 630
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKHKTesTIILVAHDiDEAIYLSDRIVLLGEG 200
Cdd:COG2274 631 RILILDEATSALDAETEAIILENLRRLLKGR--TVIIIAHR-LSTIRLADRIIVLDKG 685
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
2-200 |
9.26e-40 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 137.08 E-value: 9.26e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKViHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQH 78
Cdd:cd03299 1 LKVENLSKDWKEFKL-KNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPekrDISYVPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTINDNIRIGFQQKISDE--------EINAQLKLVDLEGRgkhFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:cd03299 80 YALFPHMTVYKNIAYGLKKRKVDKkeierkvlEIAEMLGIDHLLNR---KPETLSGGEQQRVAIARALVVNPKILLLDEP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 151 LGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03299 157 FSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNG 206
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
10-200 |
1.26e-39 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 140.55 E-value: 1.26e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLFQHHNLLPWKT 86
Cdd:PRK11000 12 AYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPaerGVGMVFQSYALYPHLS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRIGFQ-QKISDEEINAQ-------LKLVDLEGRGkhfPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:PRK11000 92 VAENMSFGLKlAGAKKEEINQRvnqvaevLQLAHLLDRK---PKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAAL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 159 RYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11000 169 RVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAG 210
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
14-200 |
1.30e-39 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 136.27 E-value: 1.30e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDIS---KGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII------DNEIKQQPSPD---CLMLFQHHNL 81
Cdd:cd03297 7 EKRLPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLngtvlfDSRKKINLPPQqrkIGLVFQQYAL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFQQKISDEE---INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:cd03297 87 FPHLNVRENLAFGLKRKRNREDrisVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 159 RYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03297 167 RLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDG 208
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-217 |
3.80e-39 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 138.29 E-value: 3.80e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF----GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDcL-- 73
Cdd:COG1135 1 MIELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGvDLTALSERE-Lra 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ------MLFQHHNLLPWKTINDNI----RIgfqQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:COG1135 80 arrkigMIFQHFNLLSSRTVAENValplEI---AGVPKAEIRKRvaelLELVGLSDKADAYPSQLSGGQKQRVGIARALA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQ---YEItASHPRS 216
Cdd:COG1135 157 NNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENG-RIVEQgpvLDV-FANPQS 234
|
.
gi 2756312332 217 R 217
Cdd:COG1135 235 E 235
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-200 |
5.81e-39 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 135.57 E-value: 5.81e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP--------D 71
Cdd:COG3638 2 MLELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGralrrlrrR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CLMLFQHHNLLPWKTINDNI------RIGFQQ----KISDEEINAQLKL---VDLEGRGKHFPEQLSGGMKQRVALCRAH 138
Cdd:COG3638 82 IGMIFQQFNLVPRLSVLTNVlagrlgRTSTWRsllgLFPPEDRERALEAlerVGLADKAYQRADQLSGGQQQRVAIARAL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG3638 162 VQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDG 223
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-200 |
1.39e-38 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 137.28 E-value: 1.39e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---DCLMLF 76
Cdd:PRK11650 3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPadrDIAMVF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIRIGFQ-QKISDEEINAQL----KLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:PRK11650 83 QNYALYPHMSVRENMAYGLKiRGMPKAEIEERVaeaaRILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPL 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 152 GALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11650 163 SNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGG 211
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-201 |
1.42e-38 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 133.94 E-value: 1.42e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQ---HHFGSHkvihnFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD---CLM 74
Cdd:PRK10771 1 MLKLTDITwlyHHLPMR-----FDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSrrpVSM 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIGF--------QQKISDEEINAQLKLVDLEGRgkhFPEQLSGGMKQRVALCRAHVHKPNVIL 146
Cdd:PRK10771 76 LFQENNLFSHLTVAQNIGLGLnpglklnaAQREKLHAIARQMGIEDLLAR---LPGQLSGGQRQRVALARCLVREQPILL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 147 MDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGC 201
Cdd:PRK10771 153 LDEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGR 207
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
1-200 |
2.19e-38 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 136.77 E-value: 2.19e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQqLQHHFGSHKVihNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD-CL------ 73
Cdd:COG4148 2 MLEVD-FRLRRGGFTL--DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGiFLpphrrr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 --MLFQHHNLLPWKTINDNIRIGF------QQKISDEEINAQLKLVDLEGRgkhFPEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:COG4148 79 igYVFQEARLFPHLSVRGNLLYGRkrapraERRISFDEVVELLGIGHLLDR---RPATLSGGERQRVAIGRALLSSPRLL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 146 LMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4148 156 LMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQG 210
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-200 |
4.29e-38 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 138.88 E-value: 4.29e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF--GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPS---SGRVIIDN-EIKQQP----SP 70
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGrDLLELSealrGR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 DCLMLFQH--HNLLPWkTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:COG1123 84 RIGMVFQDpmTQLNPV-TVGDQIAEALEnLGLSRAEARARvlelLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1123 163 LLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDG 219
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
17-150 |
4.38e-38 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 130.08 E-value: 4.38e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----MLFQHHNLLPWKTINDNI 91
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLrkeigYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 92 RIG-----FQQKISDEEINAQLKLVDLEGRGKH----FPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:pfam00005 81 RLGlllkgLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-203 |
5.79e-38 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 130.63 E-value: 5.79e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 3 KIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNeikqqpspdclmlfqhHNLL 82
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDG----------------KDLA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 83 PWKTINDNIRIGF--QqkisdeeinaQLKLVDLEG-RGKHFpEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:cd03214 65 SLSPKELARKIAYvpQ----------ALELLGLAHlADRPF-NELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQ 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2756312332 160 YKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNI 203
Cdd:cd03214 134 IELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIV 177
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
1-187 |
1.20e-37 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 131.06 E-value: 1.20e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHP---SSGRVIIDNEikqqpSPDCL---- 73
Cdd:COG4136 1 MLSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGR-----RLTALpaeq 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ----MLFQHHNLLPWKTINDNIRIGFQQKISDEE----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:COG4136 76 rrigILFQDDLLFPHLSVGENLAFALPPTIGRAQrrarVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRAL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 146 LMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEA 187
Cdd:COG4136 156 LLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDA 197
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-200 |
4.11e-37 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 130.60 E-value: 4.11e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-----------EIKQQPS 69
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGlkvndpkvderLIRQEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 70 pdclMLFQHHNLLPWKTINDNIRIGFQQ--KISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:PRK09493 81 ----MVFQQFYLFPHLTALENVMFGPLRvrGASKEEAEKQarelLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPK 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 144 VILMDEPLGALDAftryKLRDQLVQ-LKHKTES--TIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK09493 157 LMLFDEPTSALDP----ELRHEVLKvMQDLAEEgmTMVIVTHEIGFAEKVASRLIFIDKG 212
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
12-200 |
5.13e-37 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 136.43 E-value: 5.13e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDclmLFQH------HNLLPW 84
Cdd:COG4988 348 GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGvDLSDLDPAS---WRRQiawvpqNPYLFA 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGfQQKISDEEINAQLKLVDLE-----------------GRGkhfpeqLSGGMKQRVALCRAHVHKPNVILM 147
Cdd:COG4988 425 GTIRENLRLG-RPDASDEELEAALEAAGLDefvaalpdgldtplgegGRG------LSGGQAQRLALARALLRDAPLLLL 497
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 148 DEPLGALDAFTRYKLRDQLVQLKHktESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:COG4988 498 DEPTAHLDAETEAEILQALRRLAK--GRTVILITHRL-ALLAQADRILVLDDG 547
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-200 |
6.43e-37 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 130.11 E-value: 6.43e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGS-HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL------ 73
Cdd:TIGR02315 1 MLEVENLSKVYPNgKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLrklrrr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 --MLFQHHNLLPWKTINDNI---RIGFQQKI-------SDEEIN---AQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAH 138
Cdd:TIGR02315 81 igMIFQHYNLIERLTVLENVlhgRLGYKPTWrsllgrfSEEDKEralSALERVGLADKAYQRADQLSGGQQQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAG 222
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-200 |
7.66e-37 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 129.82 E-value: 7.66e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---------- 70
Cdd:COG1121 6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRrigyvpqrae 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 ----------DCLM--LFQHHNLLPWKTINDNirigfqqkisdEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAH 138
Cdd:COG1121 86 vdwdfpitvrDVVLmgRYGRRGLFRRPSRADR-----------EAVDEALERVGLEDLADRPIGELSGGQQQRVLLARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG1121 155 AQDPDLLLLDEPFAGVDAATEEALYELLREL-RREGKTILVVTHDLGAVREYFDRVLLLNRG 215
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
12-200 |
1.39e-36 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 127.11 E-value: 1.39e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----MLFQHHNLLPwKT 86
Cdd:cd03228 13 RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLrkniaYVPQDPFLFS-GT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIrigfqqkisdeeinaqlklvdlegrgkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQL 166
Cdd:cd03228 92 IRENI--------------------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEAL 139
|
170 180 190
....*....|....*....|....*....|....
gi 2756312332 167 vqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03228 140 --RALAKGKTVIVIAHRL-STIRDADRIIVLDDG 170
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-200 |
1.85e-36 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 128.84 E-value: 1.85e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGS-HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL------- 73
Cdd:cd03256 1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALrqlrrqi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -MLFQHHNLLPWKTINDNIRIG----------FQQKISDEEINAQLKLVDLEG-RGKHFP--EQLSGGMKQRVALCRAHV 139
Cdd:cd03256 81 gMIFQQFNLIERLSVLENVLSGrlgrrstwrsLFGLFPKEEKQRALAALERVGlLDKAYQraDQLSGGQQQRVAIARALM 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03256 161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDG 221
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-200 |
1.92e-36 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 127.72 E-value: 1.92e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD-----CLMlf 76
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEAlrrigALI-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIRIGFQQK-ISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:cd03268 79 EAPGFYPNLTARENLRLLARLLgIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLD 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2756312332 156 AFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03268 159 PDGIKELRELILSLR-DQGITVLISSHLLSEIQKVADRIGIINKG 202
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-246 |
6.18e-36 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 129.92 E-value: 6.18e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF--GSHKVI--HNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL--- 73
Cdd:PRK11153 1 MIELKNISKVFpqGGRTIHalNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELrka 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -----MLFQHHNLLPWKTINDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:PRK11153 81 rrqigMIFQHFNLLSSRTVFDNVALPLElAGTPKAEIKARvtelLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 144 VILMDEPLGALD-AFTRYKLrDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQ---YEITAsHPRsrnd 219
Cdd:PRK11153 161 VLLCDEATSALDpATTRSIL-ELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAG-RLVEQgtvSEVFS-HPK---- 233
|
250 260
....*....|....*....|....*..
gi 2756312332 220 sHLLKiRNEIMETFalnhHQVEPEYYL 246
Cdd:PRK11153 234 -HPLT-REFIQSTL----HLDLPEDYL 254
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
1-200 |
6.25e-36 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 126.59 E-value: 6.25e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI------KQQPSpdcL 73
Cdd:TIGR02673 1 MIEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDvnrlrgRQLPL---L 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -----MLFQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:TIGR02673 78 rrrigVVFQDFRLLPDRTVYENVALplevrGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR02673 158 LLLADEPTGNLDPDLSERILDLLKRL-NKRGTTVIVATHDLSLVDRVAHRVIILDDG 213
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
17-200 |
1.48e-35 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 130.15 E-value: 1.48e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---------EIKQQPSPDCLMLFQHHNLLPWKTI 87
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGvdiakisdaELREVRRKKIAMVFQSFALMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 NDNIRIGFQ-QKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:PRK10070 124 LDNTAFGMElAGINAEERREKaldaLRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEM 203
|
170 180 190
....*....|....*....|....*....|....*...
gi 2756312332 163 RDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10070 204 QDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNG 241
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-200 |
4.99e-35 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 124.54 E-value: 4.99e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGS--HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLML---- 75
Cdd:cd03263 1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSlgyc 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:cd03263 81 PQFDALFDELTVREHLRFyarlkGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 151 LGALDAFTRYKLRDQLvqLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03263 161 TSGLDPASRRAIWDLI--LEVRKGRSIILTTHSMDEAEALCDRIAIMSDG 208
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
6-200 |
5.24e-35 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 127.92 E-value: 5.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 6 QLQHHFGSHKVihNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD-CL--------MLF 76
Cdd:TIGR02142 4 RFSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGiFLppekrrigYVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIRIGF------QQKISDEEINAQLKLVDLEGRGkhfPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:TIGR02142 82 QEARLFPHLSVRGNLRYGMkrarpsERRISFERVIELLGIGHLLGRL---PGRLSGGEKQRVAIGRALLSSPRLLLMDEP 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 151 LGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR02142 159 LAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDG 208
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-199 |
8.00e-35 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 123.36 E-value: 8.00e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSP---DCLMLF 76
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEpIRDAREDyrrRLAYLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 qHHNLLpwK---TINDNIRigFQQKI-----SDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:COG4133 82 -HADGL--KpelTVRENLR--FWAALyglraDREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQlkHKTESTIILVA-HDIDEaiYLSDRIVLLGE 199
Cdd:COG4133 157 EPFTALDAAGVALLAELIAA--HLARGGAVLLTtHQPLE--LAAARVLDLGD 204
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
11-197 |
4.62e-34 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 121.87 E-value: 4.62e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLlPWK---TI 87
Cdd:cd03235 9 YGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGYVPQRRSI-DRDfpiSV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 ND------NIRIGFQQKISDEE---INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:cd03235 88 RDvvlmglYGHKGLFRRLSKADkakVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKT 167
|
170 180 190
....*....|....*....|....*....|....*....
gi 2756312332 159 RYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:cd03235 168 QEDIYELLREL-RREGMTILVVTHDLGLVLEYFDRVLLL 205
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-203 |
9.46e-34 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 121.39 E-value: 9.46e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDCLML----- 75
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEdITGLPPHEIARLgigrt 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPWKTINDNIRIGFQQK-----------ISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVH 140
Cdd:cd03219 81 FQIPRLFPELTVLENVMVAAQARtgsglllararREEREARERaeelLERVGLADLADRPAGELSYGQQRRLEIARALAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 141 KPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTeSTIILVAHDIDEAIYLSDRIVLLGEGCNI 203
Cdd:cd03219 161 DPKLLLLDEPAAGLNPEETEELAELIRELRERG-ITVLLVEHDMDVVMSLADRVTVLDQGRVI 222
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
12-200 |
3.22e-33 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 126.03 E-value: 3.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----MLFQHHNLLPwKT 86
Cdd:COG4987 346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLrrriaVVPQRPHLFD-TT 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:COG4987 425 LRENLRLA-RPDATDEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLD 503
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2756312332 156 AFTRYKLRDQLvqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:COG4987 504 AATEQALLADL--LEALAGRTVLLITHRL-AGLERMDRILVLEDG 545
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-200 |
3.23e-33 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 121.00 E-value: 3.23e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHF--GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN----------EIKQQps 69
Cdd:TIGR04520 1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGldtldeenlwEIRKK-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 70 pdCLMLFQH-HNLLPWKTINDNIRIGFQ-QKISDEEI----NAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:TIGR04520 79 --VGMVFQNpDNQFVGATVEDDVAFGLEnLGVPREEMrkrvDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIyLSDRIVLLGEG 200
Cdd:TIGR04520 157 IIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKG 212
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
15-200 |
3.89e-33 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 119.43 E-value: 3.89e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID----NEIKQQPSP----DCLMLFQHHNLLPWKT 86
Cdd:cd03292 15 AALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNgqdvSDLRGRAIPylrrKIGVVFQDFRLLPDRN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIR-----IGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:cd03292 95 VYENVAfalevTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWE 174
|
170 180 190
....*....|....*....|....*....|....*....
gi 2756312332 162 LRDqLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03292 175 IMN-LLKKINKAGTTVVVATHAKELVDTTRHRVIALERG 212
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-200 |
2.84e-32 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 118.34 E-value: 2.84e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----ML 75
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELarrraVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNL-LPWkTINDNIRIG-----FQQKISDEEINAQLKLVDLEG-RGKHFPeQLSGGMKQRVALCRA------HVHKP 142
Cdd:PRK13548 82 PQHSSLsFPF-TVEEVVAMGraphgLSRAEDDALVAAALAQVDLAHlAGRDYP-QLSGGEQQRVQLARVlaqlwePDGPP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 143 NVILMDEPLGALDaftrykLRDQLV------QLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13548 160 RWLLLDEPTSALD------LAHQHHvlrlarQLAHERGLAVIVVLHDLNLAARYADRIVLLHQG 217
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
12-200 |
3.16e-32 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 123.35 E-value: 3.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPsPDCL-----MLFQHHNLLPwK 85
Cdd:COG1132 351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGvDIRDLT-LESLrrqigVVPQDTFLFS-G 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGAL 154
Cdd:COG1132 429 TIRENIRYG-RPDATDEEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARALLKDPPILILDEATSAL 507
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 155 DAFTRYKLRDQLVQLKHKTesTIILVAHDideaiyLS-----DRIVLLGEG 200
Cdd:COG1132 508 DTETEALIQEALERLMKGR--TTIVIAHR------LStirnaDRILVLDDG 550
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-224 |
5.64e-32 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 117.04 E-value: 5.64e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---EIKQQPSP-------- 70
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhfDFSKTPSDkairelrr 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 DCLMLFQHHNLLPWKTINDN-----IRIgfqQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHK 141
Cdd:PRK11124 83 NVGMVFQQYNLWPHLTVQQNlieapCRV---LGLSKDQALARaeklLERLRLKPYADRFPLHLSGGQQQRVAIARALMME 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 142 PNVILMDEPLGALDAftryKLRDQLVQLKHK---TESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQYEITA-SHPRSR 217
Cdd:PRK11124 160 PQVLLFDEPTAALDP----EITAQIVSIIRElaeTGITQVIVTHEVEVARKTASRVVYMENG-HIVEQGDASCfTQPQTE 234
|
....*..
gi 2756312332 218 NDSHLLK 224
Cdd:PRK11124 235 AFKNYLS 241
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-197 |
6.35e-32 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 122.01 E-value: 6.35e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD-----CLML 75
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADswrdqIAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPwKTINDNIRIGfQQKISDEEINAQLKLVDLE------GRGKHFP-----EQLSGGMKQRVALCRAHVHKPNV 144
Cdd:TIGR02857 402 PQHPFLFA-GTIAENIRLA-RPDASDAEIREALERAGLDefvaalPQGLDTPigeggAGLSGGQAQRLALARAFLRDAPL 479
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLkhKTESTIILVAHDiDEAIYLSDRIVLL 197
Cdd:TIGR02857 480 LLLDEPTAHLDAETEAEVLEALRAL--AQGRTVLLVTHR-LALAALADRIVVL 529
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-203 |
1.92e-31 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 116.29 E-value: 1.92e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDCLML---- 75
Cdd:COG0411 4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRdITGLPPHRIARLgiar 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 -FQHHNLLPWKTINDNIRIGFQQKIS--------------------DEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVAL 134
Cdd:COG0411 84 tFQNPRLFPELTVLENVLVAAHARLGrgllaallrlprarreereaRERAEELLERVGLADRADEPAGNLSYGQQRRLEI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 135 CRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNI 203
Cdd:COG0411 164 ARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVI 232
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-217 |
4.49e-31 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 115.23 E-value: 4.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII-DNEI-------KQQPSPDC 72
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgDITIdtarslsQQKGLIRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 73 L-----MLFQHHNLLPWKTINDNIRIG--FQQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHK 141
Cdd:PRK11264 83 LrqhvgFVFQNFNLFPHRTVLENIIEGpvIVKGEPKEEATARarelLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 142 PNVILMDEPLGALDAFTRYKLRDQLVQLKHKtESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQYEITA-----SHPRS 216
Cdd:PRK11264 163 PEVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQG-RIVEQGPAKAlfadpQQPRT 240
|
.
gi 2756312332 217 R 217
Cdd:PRK11264 241 R 241
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
2-224 |
7.75e-31 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 114.34 E-value: 7.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE---IKQQPSPDCL----- 73
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfdFSQKPSEKAIrllrq 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ---MLFQHHNLLPWKTINDN-----IRIGFQQK----ISDEEINAQLKLVDLEGRgkhFPEQLSGGMKQRVALCRAHVHK 141
Cdd:COG4161 83 kvgMVFQQYNLWPHLTVMENlieapCKVLGLSKeqarEKAMKLLARLRLTDKADR---FPLHLSGGQQQRVAIARALMME 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 142 PNVILMDEPLGALDAftryKLRDQLV----QLKHkTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQYEITA-SHPRS 216
Cdd:COG4161 160 PQVLLFDEPTAALDP----EITAQVVeiirELSQ-TGITQVIVTHEVEFARKVASQVVYMEKG-RIIEQGDASHfTQPQT 233
|
....*...
gi 2756312332 217 RNDSHLLK 224
Cdd:COG4161 234 EAFAHYLS 241
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-195 |
9.88e-31 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 115.92 E-value: 9.88e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF----GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHP---SSGRVIIDN---------EI 64
Cdd:COG0444 1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGedllklsekEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 65 KQQPSPDCLMLFQHhnllPWKTINDNIRIGFQ--------QKISDEEINAQ----LKLVDL---EGRGKHFPEQLSGGMK 129
Cdd:COG0444 81 RKIRGREIQMIFQD----PMTSLNPVMTVGDQiaeplrihGGLSKAEARERaielLERVGLpdpERRLDRYPHELSGGMR 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 130 QRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIV 195
Cdd:COG0444 157 QRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVA 222
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-200 |
1.74e-30 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 113.64 E-value: 1.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDcL-----M 74
Cdd:COG4604 1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGlDVATTPSRE-LakrlaI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLlpwktindNIRI------GF--------------QQKIsDEEInAQLKLVDLEGRgkhFPEQLSGGMKQR--V 132
Cdd:COG4604 80 LRQENHI--------NSRLtvrelvAFgrfpyskgrltaedREII-DEAI-AYLDLEDLADR---YLDELSGGQRQRafI 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 133 ALCRAhvHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4604 147 AMVLA--QDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDG 212
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-197 |
3.89e-30 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 110.21 E-value: 3.89e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPdclmlfqhhnl 81
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASP----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 lpwktiNDNIRIGfqqkISdeeinaqlkLVdlegrgkHfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:cd03216 70 ------RDARRAG----IA---------MV-------Y---QLSVGERQMVEIARALARNARLLILDEPTAALTPAEVER 120
|
170 180 190
....*....|....*....|....*....|....*.
gi 2756312332 162 LRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:cd03216 121 LFKVIRRLR-AQGVAVIFISHRLDEVFEIADRVTVL 155
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-200 |
3.76e-29 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 108.82 E-value: 3.76e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGeIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPdclmLFQHHN 80
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQdVLKQPQK----LRRRIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWK-TINDNIRI-----------GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:cd03264 76 YLPQEfGVYPNFTVrefldyiawlkGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLkhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03264 156 EPTAGLDPEERIRFRNLLSEL--GEDRIVILSTHIVEDVESLCNQVAVLNKG 205
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
14-201 |
9.56e-29 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 108.06 E-value: 9.56e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLM----LFQHHNLLPWKTIND 89
Cdd:cd03245 17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRrnigYVPQDVTLFYGTLRD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 90 NIRIGfQQKISDEEINAQLKL------VDLEGRGKHFP-----EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:cd03245 97 NITLG-APLADDERILRAAELagvtdfVNKHPNGLDLQigergRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNS 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2756312332 159 RYKLRDQLVQ-LKHKtesTIILVAHDIdEAIYLSDRIVLLGEGC 201
Cdd:cd03245 176 EERLKERLRQlLGDK---TLIIITHRP-SLLDLVDRIIVMDSGR 215
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
16-191 |
1.03e-28 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 108.36 E-value: 1.03e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP---------DCLMLFQHHNLLPWKT 86
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSaakaelrnqKLGFIYQFHHLLPDFT 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:PRK11629 104 ALENVAMplligKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADS 183
|
170 180 190
....*....|....*....|....*....|
gi 2756312332 162 LRDQLVQLKHKTESTIILVAHDIDEAIYLS 191
Cdd:PRK11629 184 IFQLLGELNRLQGTAFLVVTHDLQLAKRMS 213
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-200 |
2.80e-28 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 107.89 E-value: 2.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----ML 75
Cdd:COG4559 1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELarrraVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNL-LPWkTINDNIRIG----FQQKISDEEINAQ-LKLVDLEG-RGKHFPeQLSGGMKQRVALCR--AHVH-----K 141
Cdd:COG4559 81 PQHSSLaFPF-TVEEVVALGraphGSSAAQDRQIVREaLALVGLAHlAGRSYQ-TLSGGEQQRVQLARvlAQLWepvdgG 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 142 PNVILMDEPLGALDAFTRYKLRDQLVQLKHKtESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4559 159 PRWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRILLLHQG 216
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-200 |
3.63e-28 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 106.75 E-value: 3.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHK----VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLML- 75
Cdd:COG4181 8 IIELRGLTKTVGTGAgeltILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 --------FQHHNLLPWKTINDNI--------RIGFQQKISDEeinaqLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:COG4181 88 rarhvgfvFQSFQLLPTLTALENVmlplelagRRDARARARAL-----LERVGLGHRLDHYPAQLSGGEQQRVALARAFA 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIyLSDRIVLLGEG 200
Cdd:COG4181 163 TEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAA-RCDRVLRLRAG 222
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
12-201 |
5.74e-28 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 104.61 E-value: 5.74e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD-------CLMlfQHHNLLPw 84
Cdd:cd03246 13 AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNelgdhvgYLP--QDDELFS- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIrigfqqkisdeeinaqlklvdlegrgkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRD 164
Cdd:cd03246 90 GSIAENI--------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQ 137
|
170 180 190
....*....|....*....|....*....|....*..
gi 2756312332 165 QLVQLKhKTESTIILVAHDIdEAIYLSDRIVLLGEGC 201
Cdd:cd03246 138 AIAALK-AAGATRIVIAHRP-ETLASADRILVLEDGR 172
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-199 |
7.61e-28 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 106.66 E-value: 7.61e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLL---N----IIGGFIHpsSGRVIIDNE-IKqqpSPDC- 72
Cdd:COG1117 12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLrclNrmndLIPGARV--EGEILLDGEdIY---DPDVd 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 73 ---L-----MLFQHHNLLPwKTINDNI----RI-GFQQK-ISDEEINAQLKLVDL----EGRGKHFPEQLSGGMKQRvaL 134
Cdd:COG1117 87 vveLrrrvgMVFQKPNPFP-KSIYDNVayglRLhGIKSKsELDEIVEESLRKAALwdevKDRLKKSALGLSGGQQQR--L 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 135 C--RAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTesTIILVAHDIDEAIYLSDRIV--LLGE 199
Cdd:COG1117 164 CiaRALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDY--TIVIVTHNMQQAARVSDYTAffYLGE 230
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
2-200 |
1.11e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 107.06 E-value: 1.11e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHF--GS---HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID-----------NEIK 65
Cdd:PRK13637 3 IKIENLTHIYmeGTpfeKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDgvditdkkvklSDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 66 QQPSpdclMLFQH--HNLLPwKTINDNIRIGFQQ-KISDEEINAQLK----LV--DLEGRGKHFPEQLSGGMKQRVALCR 136
Cdd:PRK13637 83 KKVG----LVFQYpeYQLFE-ETIEKDIAFGPINlGLSEEEIENRVKramnIVglDYEDYKDKSPFELSGGQKRRVAIAG 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 137 AHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13637 158 VVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKG 221
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
10-201 |
1.32e-27 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 105.39 E-value: 1.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSH---KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IK--QQPS--------PDCLML 75
Cdd:cd03253 7 TFAYDpgrPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQdIRevTLDSlrraigvvPQDTVL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQhhnllpwKTINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRVALCRAHVHKPNV 144
Cdd:cd03253 87 FN-------DTIGYNIRYG-RPDATDEEVIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAILKNPPI 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQL-KHKtesTIILVAHDIDEaIYLSDRIVLLGEGC 201
Cdd:cd03253 159 LLLDEATSALDTHTEREIQAALRDVsKGR---TTIVIAHRLST-IVNADKIIVLKDGR 212
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
15-200 |
1.71e-27 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 104.26 E-value: 1.71e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI--KQQPSPDCLMLFQH--HNLLPwKTINDN 90
Cdd:cd03226 14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPikAKERRKSIGYVMQDvdYQLFT-DSVREE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGFQQK-ISDEEINAQLKLVDLEG-RGKHfPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQ 168
Cdd:cd03226 93 LLLGLKELdAGNEQAETVLKDLDLYAlKERH-PLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRE 171
|
170 180 190
....*....|....*....|....*....|..
gi 2756312332 169 LKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03226 172 LA-AQGKAVIVITHDYEFLAKVCDRVLLLANG 202
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
1-200 |
1.83e-27 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 107.65 E-value: 1.83e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQqLQHHFGSHKVihNFNLDI-SKGeiVTFI-GKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD-CL---- 73
Cdd:PRK11144 1 MLELN-FKQQLGDLCL--TVNLTLpAQG--ITAIfGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGiCLppek 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ----MLFQHHNLLPWKTINDNIRIGFQQKiSDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK11144 76 rrigYVFQDARLFPHYKVRGNLRYGMAKS-MVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11144 155 PLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQG 205
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-197 |
2.86e-27 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 105.31 E-value: 2.86e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPS-----SGRVIIDNEIKQQPSPDCL--- 73
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIYSPDVDPIevr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ----MLFQHHNLLPWKTINDNIRIGFQ-------QKISDEEINAQLKLVDL----EGRGKHFPEQLSGGMKQRVALCRAH 138
Cdd:PRK14267 85 revgMVFQYPNPFPHLTIYDNVAIGVKlnglvksKKELDERVEWALKKAALwdevKDRLNDYPSNLSGGQRQRLVIARAL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLkhKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:PRK14267 165 AMKPKILLMDEPTANIDPVGTAKIEELLFEL--KKEYTIVLVTHSPAQAARVSDYVAFL 221
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
13-200 |
3.45e-27 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 103.70 E-value: 3.45e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 13 SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI---KQQPspdclmlfqhhnllpW---KT 86
Cdd:cd03250 17 TSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSIayvSQEP---------------WiqnGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRIG--FQQKISDEEINA-QLKLvDLegrgKHFPEQ-----------LSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:cd03250 82 IRENILFGkpFDEERYEKVIKAcALEP-DL----EILPDGdlteigekginLSGGQKQRISLARAVYSDADIYLLDDPLS 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDeaiYLS--DRIVLLGEG 200
Cdd:cd03250 157 AVDAHVGRHIFENCILGLLLNNKTRILVTHQLQ---LLPhaDQIVVLDNG 203
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-192 |
6.32e-27 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 104.48 E-value: 6.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLL-------NIIGGFihPSSGRVIIDNEIKQQPSPDCL- 73
Cdd:PRK14243 11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILrcfnrlnDLIPGF--RVEGKVTFHGKNLYAPDVDPVe 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ------MLFQHHNLLPwKTINDNI----RI-GFQQKIsDEEINAQLKLVDLEGRGKHFPEQ----LSGGMKQRVALCRAH 138
Cdd:PRK14243 89 vrrrigMVFQKPNPFP-KSIYDNIaygaRInGYKGDM-DELVERSLRQAALWDEVKDKLKQsglsLSGGQQQRLCIARAI 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHktESTIILVAHDIDEAIYLSD 192
Cdd:PRK14243 167 AVQPEVILMDEPCSALDPISTLRIEELMHELKE--QYTIIIVTHNMQQAARVSD 218
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-200 |
8.01e-27 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 102.74 E-value: 8.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEiKQQPSPDCLM--LFQHH 79
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGK-PLDIAARNRIgyLPEER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NLLPWKTINDNIRIGFQQK-ISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGAL 154
Cdd:cd03269 80 GLYPKMKVIDQLVYLAQLKgLKKEEARRRidewLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 155 DAFTRYKLRDQLVQLKHKtESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03269 160 DPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKG 204
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
10-200 |
9.00e-27 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 104.78 E-value: 9.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID--------NEIKQQPSpdclMLFQHHNL 81
Cdd:TIGR01188 2 VYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAgydvvrepRKVRRSIG----IVPQYASV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:TIGR01188 78 DEDLTGRENLEMmgrlyGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDP 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2756312332 157 FTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR01188 158 RTRRAIWDYIRALK-EEGVTILLTTHYMEEADKLCDRIAIIDHG 200
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-200 |
1.35e-26 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 102.65 E-value: 1.35e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQL-QHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID----NEIKQQPSP----D 71
Cdd:PRK10908 1 MIRFEHVsKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSghdiTRLKNREVPflrrQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CLMLFQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVIL 146
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAIpliiaGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 147 MDEPLGALD-AFTRYKLRdqLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10908 161 ADEPTGNLDdALSEGILR--LFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDG 213
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
11-197 |
2.50e-26 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 101.16 E-value: 2.50e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIK-----QQPS-PDCL---------M- 74
Cdd:NF040873 2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARvayvpQRSEvPDSLpltvrdlvaMg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIgfqqkisdEEINAQLKLVDLEGRGKHfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGAL 154
Cdd:NF040873 82 RWARRGLWRRLTRDDRAAV--------DDALERVGLADLAGRQLG---ELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 155 DAFTRYKLRDQLVQLkHKTESTIILVAHDIDEAIyLSDRIVLL 197
Cdd:NF040873 151 DAESRERIIALLAEE-HARGATVVVVTHDLELVR-RADPCVLL 191
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
1-183 |
2.61e-26 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 102.16 E-value: 2.61e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGS--HK--VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII--------DNEIKQQ- 67
Cdd:PRK10584 6 IVEVHHLKKSVGQgeHElsILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLvgqplhqmDEEARAKl 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 68 PSPDCLMLFQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKP 142
Cdd:PRK10584 86 RAKHVGFVFQSFMLIPTLNALENVELpallrGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRP 165
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHD 183
Cdd:PRK10584 166 DVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHD 206
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-200 |
2.75e-26 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 106.43 E-value: 2.75e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-----GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII---DNEIKQ-QPSPD 71
Cdd:TIGR03269 279 IIKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgDEWVDMtKPGPD 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CL--------MLFQHHNLLPWKTINDN----IRIGFQQKISDEEINAQLKLVDLEGRG-----KHFPEQLSGGMKQRVAL 134
Cdd:TIGR03269 359 GRgrakryigILHQEYDLYPHRTVLDNlteaIGLELPDELARMKAVITLKMVGFDEEKaeeilDKYPDELSEGERHRVAL 438
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 135 CRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR03269 439 AQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDG 504
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-206 |
3.44e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 102.76 E-value: 3.44e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHK--VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL----- 73
Cdd:PRK13632 7 MIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIrkkig 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQH-HNLLPWKTINDNIRIGFQQK-ISDEEINAQL----KLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILM 147
Cdd:PRK13632 87 IIFQNpDNQFIGATVEDDIAFGLENKkVPPKKMKDIIddlaKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIF 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 148 DEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIyLSDRIVLLGEGcNIISQ 206
Cdd:PRK13632 167 DESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEG-KLIAQ 223
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
15-205 |
4.59e-26 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 105.96 E-value: 4.59e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL---------MLFQHHNLLPWK 85
Cdd:PRK10535 22 EVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALaqlrrehfgFIFQRYHLLSHL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:PRK10535 102 TAAQNVEVpavyaGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGE 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2756312332 161 KLRDQLVQLKHKTEsTIILVAHDIDEAIYlSDRIVLLGEGcNIIS 205
Cdd:PRK10535 182 EVMAILHQLRDRGH-TVIIVTHDPQVAAQ-AERVIEIRDG-EIVR 223
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
16-201 |
5.92e-26 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 101.25 E-value: 5.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL----MLFQHHNLLPW-----KT 86
Cdd:cd03267 36 ALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLrrigVVFGQKTQLWWdlpviDS 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRIgfqQKISDEEINAQL-KLVDLEGRGK--HFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:cd03267 116 FYLLAAI---YDLPPARFKKRLdELSELLDLEEllDTPvRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENI 192
|
170 180 190
....*....|....*....|....*....|....*....
gi 2756312332 163 RDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGC 201
Cdd:cd03267 193 RNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGR 231
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-200 |
7.48e-26 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 100.59 E-value: 7.48e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDCL-----ML 75
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRdITGLPPHERAragigYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPWKTINDNIRIGFQQKiSDEEINAQLKLV-----DLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:cd03224 81 PEGRRIFPELTVEENLLLGAYAR-RRAKRKARLERVyelfpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEP 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 151 LGALDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03224 160 SEGLAPKIVEEIFEAIRELR-DEGVTILLVEQNARFALEIADRAYVLERG 208
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
10-205 |
1.17e-25 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 104.33 E-value: 1.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCL-----MLFQHHNLLP 83
Cdd:COG1129 13 SFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPrDAQaagiaIIHQELNLVP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 84 WKTINDNIRIGFQQK----ISDEEINAQ----LKLVDLegrgkHFP-----EQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:COG1129 93 NLSVAENIFLGREPRrgglIDWRAMRRRarelLARLGL-----DIDpdtpvGDLSVAQQQLVEIARALSRDARVLILDEP 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 151 LGALDA------FT--RyKLRDQLVqlkhktesTIILVAHDIDEAIYLSDRIVLLGEGCNIIS 205
Cdd:COG1129 168 TASLTEreverlFRiiR-RLKAQGV--------AIIYISHRLDEVFEIADRVTVLRDGRLVGT 221
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-200 |
1.78e-25 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 99.75 E-value: 1.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII--------DNEIKQQPSpdcl 73
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVaghdvvrePREVRRRIG---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:cd03265 77 IVFQDLSVDDELTGWENLYIharlyGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03265 157 EPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHG 208
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-192 |
1.86e-25 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 100.61 E-value: 1.86e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL------- 73
Cdd:PRK11831 7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLytvrkrm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -MLFQHHNLLPWKTINDNIRIGFQQ--KISDEEINA----QLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVIL 146
Cdd:PRK11831 87 sMLFQSGALFTDMNVFDNVAYPLREhtQLPAPLLHStvmmKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIM 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 147 MDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSD 192
Cdd:PRK11831 167 FDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIAD 212
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-193 |
2.60e-25 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 99.85 E-value: 2.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIG--GFIHPS---SGRVIIDNEIKQQPSPDCL-- 73
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNPEvtiTGSIVYNGHNIYSPRTDTVdl 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -----MLFQHHNLLPWkTINDNIRIGFQ------QKISDEEINAQLKLV----DLEGRGKHFPEQLSGGMKQRVALCRAH 138
Cdd:PRK14239 85 rkeigMVFQQPNPFPM-SIYENVVYGLRlkgikdKQVLDEAVEKSLKGAsiwdEVKDRLHDSALGLSGGQQQRVCIARVL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTesTIILVAHDIDEAIYLSDR 193
Cdd:PRK14239 164 ATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDR 216
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-183 |
3.88e-25 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 96.36 E-value: 3.88e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRViidneikqqpspdclmlfqhhnl 81
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV----------------------- 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 lpwkTINDNIRIGfqqkisdeeinaqlklvdlegrgkHFPeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:cd03221 58 ----TWGSTVKIG------------------------YFE-QLSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEA 108
|
170 180
....*....|....*....|..
gi 2756312332 162 LRDQLVQLKHktesTIILVAHD 183
Cdd:cd03221 109 LEEALKEYPG----TVILVSHD 126
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
1-218 |
4.99e-25 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 99.49 E-value: 4.99e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSH---------KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP- 70
Cdd:TIGR02769 2 LLEVRDVTHTYRTGglfgakqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 -------DCLMLFQ--HHNLLPWKTINDNIRIGFQQKIS------DEEINAQLKLVDLEGR-GKHFPEQLSGGMKQRVAL 134
Cdd:TIGR02769 82 qrrafrrDVQLVFQdsPSAVNPRMTVRQIIGEPLRHLTSldeseqKARIAELLDMVGLRSEdADKLPRQLSGGQLQRINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 135 CRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQ----YEIT 210
Cdd:TIGR02769 162 ARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKG-QIVEEcdvaQLLS 240
|
....*...
gi 2756312332 211 ASHPRSRN 218
Cdd:TIGR02769 241 FKHPAGRN 248
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-211 |
5.22e-25 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 99.00 E-value: 5.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVI-----------IDnEIKQQ-- 67
Cdd:COG1119 3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrlfgerrggedVW-ELRKRig 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 68 -PSPDclmlfQHHNLLPWKTINDNIR------IGFQQKISDEEIN---AQLKLVDLEGRGKHFPEQLSGGMKQRVALCRA 137
Cdd:COG1119 82 lVSPA-----LQLRFPRDETVLDVVLsgffdsIGLYREPTDEQRErarELLELLGLAHLADRPFGTLSQGEQRRVLIARA 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 138 HVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQYEITA 211
Cdd:COG1119 157 LVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDG-RVVAAGPKEE 229
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
14-206 |
6.81e-25 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 98.07 E-value: 6.81e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCL----MLFQHHNLLPwKTIN 88
Cdd:cd03254 16 KPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGiDIRDISRKSLRsmigVVLQDTFLFS-GTIM 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAF 157
Cdd:cd03254 95 ENIRLG-RPNATDEEVIEAAKEAGAHDFIMKLPNgydtvlgenggNLSQGERQLLAIARAMLRDPKILILDEATSNIDTE 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 158 TRYKLRDQLVQLKHKTesTIILVAHDIDeAIYLSDRIVLLGEGcNIISQ 206
Cdd:cd03254 174 TEKLIQEALEKLMKGR--TSIIIAHRLS-TIKNADKILVLDDG-KIIEE 218
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
1-200 |
6.95e-25 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 98.75 E-value: 6.95e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN------EIKQQPSPDCLM 74
Cdd:TIGR02323 3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMrsgaelELYQLSEAERRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHnllpWKTINDNIRIGFQQKIS--------------------DEEINAQLKLVDLE-GRGKHFPEQLSGGMKQRVA 133
Cdd:TIGR02323 83 LMRTE----WGFVHQNPRDGLRMRVSaganigerlmaigarhygniRATAQDWLEEVEIDpTRIDDLPRAFSGGMQQRLQ 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 134 LCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR02323 159 IARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQG 225
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
14-200 |
8.31e-25 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 98.38 E-value: 8.31e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDCLMLF----QHHNLLPwKTIN 88
Cdd:cd03249 16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVdIRDLNLRWLRSQIglvsQEPVLFD-GTIA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAF 157
Cdd:cd03249 95 ENIRYG-KPDATDEEVEEAAKKANIHDFIMSLPDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLDEATSALDAE 173
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 158 TRYKLRDQLVQLkhKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03249 174 SEKLVQEALDRA--MKGRTTIVIAHRL-STIRNADLIAVLQNG 213
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-200 |
1.15e-24 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 99.03 E-value: 1.15e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEikqqpspdclmlfqhhn 80
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGE----------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWKTINdniRIGF---------QQKISD-----------------EEINAQLKLVDLEGRGKHFPEQLSGGMKQRVAL 134
Cdd:COG4152 64 PLDPEDRR---RIGYlpeerglypKMKVGEqlvylarlkglskaeakRRADEWLERLGLGDRANKKVEELSKGNQQKVQL 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 135 CRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4152 141 IAALLHDPELLILDEPFSGLDPVNVELLKDVIRELA-AKGTTVIFSSHQMELVEELCDRIVIINKG 205
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
2-206 |
1.16e-24 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 102.13 E-value: 1.16e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFG-SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPspDCLMLFQHHN 80
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDI--DRHTLRQFIN 551
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWK------TINDNIRIGFQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPN 143
Cdd:TIGR01193 552 YLPQEpyifsgSILENLLLGAKENVSQDEIWAACEIAEIKDDIENMPLgyqtelseegsSISGGQKQRIALARALLTDSK 631
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHKtesTIILVAHDIDEAiYLSDRIVLLGEGcNIISQ 206
Cdd:TIGR01193 632 VLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVA-KQSDKIIVLDHG-KIIEQ 689
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-183 |
1.37e-24 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 101.29 E-value: 1.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 4 IQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKqqpspdCLMLFQHHNLLP 83
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLR------IGYLPQEPPLDD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 84 WKTINDNIRIGFQ--QKISDE--EINAQL--------KLVDLEGR------------------GKHFPE--------QLS 125
Cdd:COG0488 75 DLTVLDTVLDGDAelRALEAEleELEAKLaepdedleRLAELQEEfealggweaearaeeilsGLGFPEedldrpvsELS 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 126 GGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHktesTIILVAHD 183
Cdd:COG0488 155 GGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPG----TVLVVSHD 208
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-206 |
1.92e-24 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 97.80 E-value: 1.92e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSS-----GRV-----------IIDNEIK 65
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVeffnqniyerrVNLNRLR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 66 QQPSpdclMLFQHHNLLPwKTINDNIR-----IGFQQKIS-DEEINAQLKLVDLEGRGKHFPEQ----LSGGMKQRVALC 135
Cdd:PRK14258 88 RQVS----MVHPKPNLFP-MSVYDNVAygvkiVGWRPKLEiDDIVESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 136 RAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNIISQ 206
Cdd:PRK14258 163 RALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENRIGQ 233
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-200 |
2.77e-24 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 96.28 E-value: 2.77e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF----GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCL-- 73
Cdd:cd03266 1 MITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfDVVKEPAEARRrl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 -MLFQHHNLLPWKTINDNIRI--------GFQQKISDEEINAQLKLVD-LEGRGKHFpeqlSGGMKQRVALCRAHVHKPN 143
Cdd:cd03266 81 gFVSDSTGLYDRLTARENLEYfaglyglkGDELTARLEELADRLGMEElLDRRVGGF----STGMRQKVAIARALVHDPP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03266 157 VLLLDEPTTGLDVMATRALREFIRQLR-ALGKCILFSTHIMQEVERLCDRVVVLHRG 212
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-200 |
2.80e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 97.88 E-value: 2.80e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGS---HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---------EIKQQP 68
Cdd:PRK13650 4 IIEVKNLTFKYKEdqeKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGdllteenvwDIRHKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 69 SpdclMLFQH-HNLLPWKTINDNIRIGFQQK-ISDEE----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKP 142
Cdd:PRK13650 84 G----MVFQNpDNQFVGATVEDDVAFGLENKgIPHEEmkerVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRP 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEaIYLSDRIVLLGEG 200
Cdd:PRK13650 160 KIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDE-VALSDRVLVMKNG 216
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
2-200 |
4.31e-24 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 95.93 E-value: 4.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCLMLFQHHN 80
Cdd:TIGR03740 1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGhPWTRKDLHKIGSLIESPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWKTINDNIRI-GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:TIGR03740 81 LYENLTARENLKVhTTLLGLPDSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGLDPIGI 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 160 YKLRdQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR03740 161 QELR-ELIRSFPEQGITVILSSHILSEVQQLADHIGIISEG 200
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-200 |
7.44e-24 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 96.24 E-value: 7.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIH----PSSGRVIIDNEI-----------K 65
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITgdksAGSHIELLGRTVqregrlardirK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 66 QQPSPDCLmlFQHHNLLPWKTINDNIRIG--------------FQQKISDEEINAqLKLVDLegrgKHFPEQ----LSGG 127
Cdd:PRK09984 84 SRANTGYI--FQQFNLVNRLSVLENVLIGalgstpfwrtcfswFTREQKQRALQA-LTRVGM----VHFAHQrvstLSGG 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 128 MKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK09984 157 QQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG 229
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
15-200 |
8.29e-24 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 95.38 E-value: 8.29e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLM----LFQHHNLLPWKTINDN 90
Cdd:cd03251 16 PVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRrqigLVSQDVFLFNDTVAEN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:cd03251 96 IAYG-RPGATREEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARALLKDPPILILDEATSALDTESE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 160 YKLRDQLVQL-KHKtesTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03251 175 RLVQAALERLmKNR---TTFVIAHRL-STIENADRIVVLEDG 212
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
13-200 |
1.19e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 95.92 E-value: 1.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 13 SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN----------EIKQQpspdCLMLFQH-HNL 81
Cdd:PRK13633 22 EKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtsdeenlwDIRNK----AGMVFQNpDNQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFQQ-KISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK13633 98 IVATIVEEDVAFGPENlGIPPEEIRERvdesLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDP 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2756312332 157 FTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:PRK13633 178 SGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSG 220
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-200 |
1.62e-23 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 95.42 E-value: 1.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPD--------- 71
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQtINLVRDKDgqlkvadkn 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 --------CLMLFQHHNLLPWKTINDNIR------IGFQQKISDEEINAQLKLVDLEGRGK-HFPEQLSGGMKQRVALCR 136
Cdd:PRK10619 86 qlrllrtrLTMVFQHFNLWSHMTVLENVMeapiqvLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGGQQQRVSIAR 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 137 AHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTEsTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGK-TMVVVTHEMGFARHVSSHVIFLHQG 228
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
9-183 |
1.79e-23 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 98.20 E-value: 1.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 9 HHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD----CLMLFQHHNLLPW 84
Cdd:TIGR02868 343 GYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDevrrRVSVCAQDAHLFD 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:TIGR02868 423 TTVRENLRLA-RPDATDEELWAALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEH 501
|
170 180 190
....*....|....*....|....*....|
gi 2756312332 154 LDAFTRYKLRDQLvqLKHKTESTIILVAHD 183
Cdd:TIGR02868 502 LDAETADELLEDL--LAALSGRTVVLITHH 529
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-200 |
1.92e-23 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 98.21 E-value: 1.92e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQ----Qpspdclmlf 76
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVKIgyfdQ--------- 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTINDNIRiGFQQKISDEEINA-----------QLKLVdlegrgkhfpEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:COG0488 386 HQEELDPDKTVLDELR-DGAPGGTEQEVRGylgrflfsgddAFKPV----------GVLSGGEKARLALAKLLLSPPNVL 454
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 146 LMDEPLGALDAFTRYKLRDQLVQLkhktESTIILVAHD---IDEaiyLSDRIVLLGEG 200
Cdd:COG0488 455 LLDEPTNHLDIETLEALEEALDDF----PGTVLLVSHDryfLDR---VATRILEFEDG 505
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-203 |
2.63e-23 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 95.64 E-value: 2.63e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLM----LFQ 77
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQrvgvVPQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK13537 88 FDNLDPDFTVRENLLVfgryfGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 153 ALDAFTRY----KLRDQLVQLKhktesTIILVAHDIDEAIYLSDRIVLLGEGCNI 203
Cdd:PRK13537 168 GLDPQARHlmweRLRSLLARGK-----TILLTTHFMEEAERLCDRLCVIEEGRKI 217
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
14-197 |
2.66e-23 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 93.75 E-value: 2.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIkqqpspdCLMLFQHHNLLPWKTINDNIRI 93
Cdd:cd03220 35 FWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRV-------SSLLGLGGGFNPELTGRENIYL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 94 -----GFQQKISDEEINAqlkLVDLEGRGKHFPEQL---SGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQ 165
Cdd:cd03220 108 ngrllGLSRKEIDEKIDE---IIEFSELGDFIDLPVktySSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRR 184
|
170 180 190
....*....|....*....|....*....|..
gi 2756312332 166 LVQLKhKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:cd03220 185 LRELL-KQGKTVILVSHDPSSIKRLCDRALVL 215
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
17-200 |
3.08e-23 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 95.08 E-value: 3.08e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---------EIKQQPSpdclMLFQH-HNLLPWKT 86
Cdd:PRK13635 23 LKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGmvlseetvwDVRRQVG----MVFQNpDNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRIGFQ-QKISDEE----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:PRK13635 99 VQDDVAFGLEnIGVPREEmverVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRRE 178
|
170 180 190
....*....|....*....|....*....|....*....
gi 2756312332 162 LRDQLVQLKHKTESTIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:PRK13635 179 VLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKG 216
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
16-200 |
4.13e-23 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 93.70 E-value: 4.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----MLFQhHNLLPWKTINDN 90
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLrrqvgVVLQ-ENVLFNRSIRDN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGfQQKISDEEINAQLKLVDL--------EGRGKHFPEQ---LSGGMKQRVALCRAHVHKPNVILMDEPLGALDaftr 159
Cdd:cd03252 96 IALA-DPGMSMERVIEAAKLAGAhdfiselpEGYDTIVGEQgagLSGGQRQRIAIARALIHNPRILIFDEATSALD---- 170
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 160 YKLRDQLVQLKHKTES--TIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03252 171 YESEHAIMRNMHDICAgrTVIIIAHRL-STVKNADRIIVMEKG 212
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-200 |
8.82e-23 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 92.74 E-value: 8.82e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPD------CL 73
Cdd:COG0410 3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEdITGLPPHRiarlgiGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLfQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLV-DLegrgkhFPE----------QLSGGMKQRVALCRAHVHKP 142
Cdd:COG0410 83 VP-EGRRIFPSLTVEENLLLGAYARRDRAEVRADLERVyEL------FPRlkerrrqragTLSGGEQQMLAIGRALMSRP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 143 NVILMDEP-LGaLDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG0410 156 KLLLLDEPsLG-LAPLIVEEIFEIIRRLN-REGVTILLVEQNARFALEIADRAYVLERG 212
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-206 |
1.21e-22 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 92.77 E-value: 1.21e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----ML 75
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLarrlaLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHnLLP-------------------WKTINDNIRIGFQQKISDEEIN--AQLKLVDlegrgkhfpeqLSGGMKQRVAL 134
Cdd:PRK11231 82 PQHH-LTPegitvrelvaygrspwlslWGRLSAEDNARVNQAMEQTRINhlADRRLTD-----------LSGGQRQRAFL 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 135 CRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTEsTIILVAHDIDEAIYLSDRIVLLGEGcNIISQ 206
Cdd:PRK11231 150 AMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGK-TVVTVLHDLNQASRYCDHLVVLANG-HVMAQ 219
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-238 |
2.73e-22 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 94.87 E-value: 2.73e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGF--IHPSSGRVI-----------IDNEIKQ-Q 67
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIyhvalcekcgyVERPSKVgE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 68 PSPDC---------------------------LMLFQHHNLLPWKTINDNI-----RIGFQQKISDEEINAQLKLVDLEG 115
Cdd:TIGR03269 81 PCPVCggtlepeevdfwnlsdklrrrirkriaIMLQRTFALYGDDTVLDNVlealeEIGYEGKEAVGRAVDLIEMVQLSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 116 RGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAH------DI-DEAI 188
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHwpevieDLsDKAI 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 189 YLSD-RIVLLGEGCNIISQYEITASHPRSRNDshlLKIRNEIMETFALNHH 238
Cdd:TIGR03269 241 WLENgEIKEEGTPDEVVAVFMEGVSEVEKECE---VEVGEPIIKVRNVSKR 288
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-204 |
2.86e-22 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 92.07 E-value: 2.86e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGS-----HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQP----SP 70
Cdd:COG1101 1 MLELKNLSKTFNPgtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKdVTKLPeykrAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 DCLMLFQH------HNLlpwkTINDNIRI--------GFQQKISDEEIN---AQLKLVD--LEGRGKHFPEQLSGGMKQR 131
Cdd:COG1101 81 YIGRVFQDpmmgtaPSM----TIEENLALayrrgkrrGLRRGLTKKRRElfrELLATLGlgLENRLDTKVGLLSGGQRQA 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 132 VALCRAHVHKPNVILMDEPLGALDAFTRYK---LRDQLVQlKHKTesTIILVAHDIDEAIYLSDRIVLLGEGcNII 204
Cdd:COG1101 157 LSLLMATLTKPKLLLLDEHTAALDPKTAALvleLTEKIVE-ENNL--TTLMVTHNMEQALDYGNRLIMMHEG-RII 228
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-200 |
3.50e-22 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 91.07 E-value: 3.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPspdclM------ 74
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQdITKLP-----Mhkrarl 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 ----LFQHHNLLPWKTINDNIR-----IGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:cd03218 76 gigyLPQEASIFRKLTVEENILavleiRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 146 LMDEPLGALDAFTRYKLRDQLVQLKhktESTI-ILVA-HDIDEAIYLSDRIVLLGEG 200
Cdd:cd03218 156 LLDEPFAGVDPIAVQDIQKIIKILK---DRGIgVLITdHNVRETLSITDRAYIIYEG 209
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
11-203 |
5.39e-22 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 92.59 E-value: 5.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEikqqPSPDCLMLF--------QHHNLL 82
Cdd:PRK13536 51 YGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGV----PVPARARLArarigvvpQFDNLD 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 83 PWKTINDNIRI-----GFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAF 157
Cdd:PRK13536 127 LEFTVRENLLVfgryfGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPH 206
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 158 TRY----KLRDQLVQLKhktesTIILVAHDIDEAIYLSDRIVLLGEGCNI 203
Cdd:PRK13536 207 ARHliweRLRSLLARGK-----TILLTTHFMEEAERLCDRLCVLEAGRKI 251
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
9-200 |
5.73e-22 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 89.41 E-value: 5.73e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 9 HHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCLML---F-----QHH 79
Cdd:cd03215 8 RGLSVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPrDAIRAgiaYvpedrKRE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NLLPWKTINDNIRIGFQqkisdeeinaqlklvdlegrgkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:cd03215 88 GLVLDLSVAENIALSSL---------------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAK 140
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 160 YKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:cd03215 141 AEIYRLIRELA-DAGKAVLLISSELDELLGLCDRILVMYEG 180
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
12-217 |
9.33e-22 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 90.90 E-value: 9.33e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVI--------IDNEIKQQPSPDCLMLFQHH---- 79
Cdd:PRK10419 23 QHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSwrgeplakLNRAQRKAFRRDIQMVFQDSisav 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NllPWKTINDNIR------IGFQQKISDEEINAQLKLVDL-EGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK10419 103 N--PRKTVREIIReplrhlLSLDKAERLARASEMLRAVDLdDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVS 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNIISQ---YEITASHPRSR 217
Cdd:PRK10419 181 NLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQpvgDKLTFSSPAGR 248
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
17-200 |
1.12e-21 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 93.92 E-value: 1.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII---DNEIKQQPSPDCL-MLFQHHNLLPWKTINDNIR 92
Cdd:TIGR01257 946 VDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVggkDIETNLDAVRQSLgMCPQHNILFHHLTVAEHIL 1025
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 93 IGFQQKISDEEiNAQLKL-VDLEGRGKHF-----PEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQL 166
Cdd:TIGR01257 1026 FYAQLKGRSWE-EAQLEMeAMLEDTGLHHkrneeAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL 1104
|
170 180 190
....*....|....*....|....*....|....
gi 2756312332 167 vqLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR01257 1105 --LKYRSGRTIIMSTHHMDEADLLGDRIAIISQG 1136
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
14-200 |
1.28e-21 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 89.45 E-value: 1.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEikqqpspdCLMLFQHHNL------------ 81
Cdd:cd03248 27 TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGK--------PISQYEHKYLhskvslvgqepv 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFQQKiSDEEINAqlkLVDLEGRGKHFPE--------------QLSGGMKQRVALCRAHVHKPNVILM 147
Cdd:cd03248 99 LFARSLQDNIAYGLQSC-SFECVKE---AAQKAHAHSFISElasgydtevgekgsQLSGGQKQRVAIARALIRNPQVLIL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 148 DEPLGALDAFTRYKLRdQLVQLKHkTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03248 175 DEATSALDAESEQQVQ-QALYDWP-ERRTVLVIAHRL-STVERADQILVLDGG 224
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
15-200 |
1.42e-21 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 89.25 E-value: 1.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPS---SGRVIIDN-EIKQQPSPDCL-MLFQHHNLLPWKTIND 89
Cdd:cd03234 21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGqPRKPDQFQKCVaYVRQDDILLPGLTVRE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 90 NIRIGFQ---QKISDEEINAQ------LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:cd03234 101 TLTYTAIlrlPRKSSDAIRKKrvedvlLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTAL 180
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 161 KLRDQLVQLKHKtESTIILVAHDIDEAIY-LSDRIVLLGEG 200
Cdd:cd03234 181 NLVSTLSQLARR-NRIVILTIHQPRSDLFrLFDRILLLSSG 220
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-200 |
2.62e-21 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 89.20 E-value: 2.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFI--HPS---SGRVIID-NEIKQQPSPD---- 71
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelYPEarvSGEVYLDgQDIFKMDVIElrrr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CLMLFQHHNLLPWKTINDNIRIG------------FQQKISDEEINAQLkLVDLEGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:PRK14247 84 VQMVFQIPNPIPNLSIFENVALGlklnrlvkskkeLQERVRWALEKAQL-WDEVKDRLDAPAGKLSGGQQQRLCIARALA 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLkhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK14247 163 FQPEVLLADEPTANLDPENTAKIESLFLEL--KKDMTIVLVTHFPQQAARISDYVAFLYKG 221
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
15-200 |
6.65e-21 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 89.38 E-value: 6.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIkqqpspdclmlfqhhnllPWKTINDNIR-I 93
Cdd:COG4586 36 EAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYV------------------PFKRRKEFARrI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 94 G--FQQK---------------------ISDEEINAQLK----LVDLEG------RgkhfpeQLSGGMKQRVALCRAHVH 140
Cdd:COG4586 98 GvvFGQRsqlwwdlpaidsfrllkaiyrIPDAEYKKRLDelveLLDLGElldtpvR------QLSLGQRMRCELAAALLH 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 141 KPNVILMDEP-LGaLDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4586 172 RPKILFLDEPtIG-LDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHG 231
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
16-215 |
6.69e-21 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 90.96 E-value: 6.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPsPDCLM-----LFQHHNLLPwKTIND 89
Cdd:COG4618 347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGaDLSQWD-REELGrhigyLPQDVELFD-GTIAE 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 90 NI-RIGfqqKISDEEINAQLKLVDLegrgkH-----FPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:COG4618 425 NIaRFG---DADPEKVVAAAKLAGV-----HemilrLPDgydtrigeggaRLSGGQRQRIGLARALYGDPRLVVLDEPNS 496
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 153 ALDAFTRYKLRDQLVQLKhKTESTIILVAHDIdEAIYLSDRIVLLGEGcniisqyEITASHPR 215
Cdd:COG4618 497 NLDDEGEAALAAAIRALK-ARGATVVVITHRP-SLLAAVDKLLVLRDG-------RVQAFGPR 550
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
16-201 |
9.37e-21 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 90.94 E-value: 9.37e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNeikqQPSPDclmlFQHHNL------------LP 83
Cdd:TIGR00958 496 VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG----VPLVQ----YDHHYLhrqvalvgqepvLF 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 84 WKTINDNIRIGFQQKiSDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:TIGR00958 568 SGSVRENIAYGLTDT-PDEEIMAAAKAANAHDFIMEFPNgydtevgekgsQLSGGQKQRIAIARALVRKPRVLILDEATS 646
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 153 ALDAFTRYKLRdqlvQLKHKTESTIILVAHDIdEAIYLSDRIVLLGEGC 201
Cdd:TIGR00958 647 ALDAECEQLLQ----ESRSRASRTVLLIAHRL-STVERADQILVLKKGS 690
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
2-200 |
1.12e-20 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 85.83 E-value: 1.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFG--SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEikqqpspdclmlfqhh 79
Cdd:cd03247 1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGV---------------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 nllPWKTINDNIRigfqQKISdeEINAQLKLVD---LEGRGKhfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:cd03247 65 ---PVSDLEKALS----SLIS--VLNQRPYLFDttlRNNLGR----RFSGGERQRLALARILLQDAPIVLLDEPTVGLDP 131
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2756312332 157 FTRYKLRDQLvqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03247 132 ITERQLLSLI--FEVLKDKTLIWITHHL-TGIEHMDKILFLENG 172
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-206 |
1.35e-20 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 90.27 E-value: 1.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLqhHFG----SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL---M 74
Cdd:PRK11160 339 LTLNNV--SFTypdqPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALrqaI 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 --------LFQHhnllpwkTINDNIRIGfQQKISDEEINAQLKLVDLE----------------GRgkhfpeQLSGGMKQ 130
Cdd:PRK11160 417 svvsqrvhLFSA-------TLRDNLLLA-APNASDEALIEVLQQVGLEklleddkglnawlgegGR------QLSGGEQR 482
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 131 RVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLvqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEGcNIISQ 206
Cdd:PRK11160 483 RLGIARALLHDAPLLLLDEPTEGLDAETERQILELL--AEHAQNKTVLMITHRL-TGLEQFDRICVMDNG-QIIEQ 554
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
16-182 |
2.06e-20 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 89.48 E-value: 2.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIdneikqqPSPDCLMLfqhhnlLPWKT--INDNIRi 93
Cdd:COG4178 378 LLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR-------PAGARVLF------LPQRPylPLGTLR- 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 94 gfQQ--------KISDEEINAQLKLVDLEgrgkHFPEQ----------LSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:COG4178 444 --EAllypataeAFSDAELREALEAVGLG----HLAERldeeadwdqvLSLGEQQRLAFARLLLHKPDWLFLDEATSALD 517
|
170 180
....*....|....*....|....*..
gi 2756312332 156 AFTRYKLRDQLVQlkHKTESTIILVAH 182
Cdd:COG4178 518 EENEAALYQLLRE--ELPGTTVISVGH 542
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-200 |
2.18e-20 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 86.47 E-value: 2.18e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID-NEIKQQPSP-----DCLM 74
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDgKDITDWQTAkimreAVAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIG--------FQQKISdeeinaqlKLVDLEGRGKHFPEQ----LSGGMKQRVALCRAHVHKP 142
Cdd:PRK11614 85 VPEGRRVFSRMTVEENLAMGgffaerdqFQERIK--------WVYELFPRLHERRIQragtMSGGEQQMLAIGRALMSQP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKHKTeSTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11614 157 RLLLLDEPSLGLAPIIIQQIFDTIEQLREQG-MTIFLVEQNANQALKLADRGYVLENG 213
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
16-200 |
2.51e-20 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 86.01 E-value: 2.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE----------------IKQQPspdclMLFQhh 79
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVdiskiglhdlrsrisiIPQDP-----VLFS-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 nllpwKTINDNIRIgFQQKiSDEEINAQLKLVDLEGRGKHFP-----------EQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:cd03244 92 -----GTIRSNLDP-FGEY-SDEELWQALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLARALLRKSKILVLD 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 149 EPLGALDAFTryklrDQLVQ--LKHK-TESTIILVAHDIDeAIYLSDRIVLLGEG 200
Cdd:cd03244 165 EATASVDPET-----DALIQktIREAfKDCTVLTIAHRLD-TIIDSDRILVLDKG 213
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
15-197 |
2.77e-20 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 87.84 E-value: 2.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVI--------IDNEIKQQPSPDCLMLFQH--HNLLPW 84
Cdd:PRK15079 35 KAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAwlgkdllgMKDDEWRAVRSDIQMIFQDplASLNPR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNI----RIgFQQKISDEEINAQLK--------LVDLEGRgkhFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK15079 115 MTIGEIIaeplRT-YHPKLSRQEVKDRVKammlkvglLPNLINR---YPHEFSGGQCQRIGIARALILEPKLIICDEPVS 190
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:PRK15079 191 ALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVM 235
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
16-200 |
2.86e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 87.06 E-value: 2.86e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-------MLFQH-HNLLPWKTI 87
Cdd:PRK13639 17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSLLevrktvgIVFQNpDDQLFAPTV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 NDNIRIG-FQQKISDEEINAQ----LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:PRK13639 97 EEDVAFGpLNLGLSKEEVEKRvkeaLKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQI 176
|
170 180 190
....*....|....*....|....*....|....*...
gi 2756312332 163 RDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13639 177 MKLLYDL-NKEGITIIISTHDVDLVPVYADKVYVMSDG 213
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
2-200 |
1.39e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 85.46 E-value: 1.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFG-----SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII-DNEIKQQPSPDCL-- 73
Cdd:PRK13634 3 ITFQKVEHRYQyktpfERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgERVITAGKKNKKLkp 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ------MLFQ--HHNLLPwKTINDNIRIGFQQ-KISDEEINAQ----LKLVDL-EGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:PRK13634 83 lrkkvgIVFQfpEHQLFE-ETVEKDICFGPMNfGVSEEDAKQKaremIELVGLpEELLARSPFELSGGQMRRVAIAGVLA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13634 162 MEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKG 222
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
17-200 |
1.53e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 85.14 E-value: 1.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----MLFQH-HNLLPWKTINDN 90
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLrrkigMVFQNpDNQFVGATVEDD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGFQ-QKISDEE----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQ 165
Cdd:PRK13642 103 VAFGMEnQGIPREEmikrVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRV 182
|
170 180 190
....*....|....*....|....*....|....*
gi 2756312332 166 LVQLKHKTESTIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:PRK13642 183 IHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAG 216
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-196 |
1.73e-19 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 83.61 E-value: 1.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD--------C 72
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEiyrqqvsyC 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 73 L---MLFQ---HHNLL-PW----------KTINDNIRIGFQQKISDEEINAqlklvdlegrgkhfpeqLSGGMKQRVALC 135
Cdd:PRK10247 87 AqtpTLFGdtvYDNLIfPWqirnqqpdpaIFLDDLERFALPDTILTKNIAE-----------------LSGGEKQRISLI 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 136 RAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVL 196
Cdd:PRK10247 150 RNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINHADKVITL 210
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-200 |
1.99e-19 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 84.21 E-value: 1.99e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN------EIKQQPSPDCLM 74
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMrdgqlrDLYALSEAERRR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHnllpWKTINDNIRIGFQQKISD----------------EEINAQ----LKLVDLE-GRGKHFPEQLSGGMKQRVA 133
Cdd:PRK11701 86 LLRTE----WGFVHQHPRDGLRMQVSAggnigerlmavgarhyGDIRATagdwLERVEIDaARIDDLPTTFSGGMQQRLQ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 134 LCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11701 162 IARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQG 228
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
10-208 |
2.56e-19 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 83.59 E-value: 2.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIkqqpSPdclML-----FqHHNLlpw 84
Cdd:COG1134 35 RREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRV----SA---LLelgagF-HPEL--- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 kTINDNIRIGFQ-QKISDEEINAQLK-LVDLEGRGKHFPEQL---SGGMKQRVAL-CRAHVhKPNVILMDEPLGALDAFT 158
Cdd:COG1134 104 -TGRENIYLNGRlLGLSRKEIDEKFDeIVEFAELGDFIDQPVktySSGMRARLAFaVATAV-DPDILLVDEVLAVGDAAF 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 159 RYKLRDQLVQLKhKTESTIILVAHDI-------DEAIYLSD-RIVLLGEGCNIISQYE 208
Cdd:COG1134 182 QKKCLARIRELR-ESGRTVIFVSHSMgavrrlcDRAIWLEKgRLVMDGDPEEVIAAYE 238
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1-205 |
4.08e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 84.01 E-value: 4.08e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFG-----SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRV-----IIDNEIKQQP-- 68
Cdd:PRK13643 1 MIKFEKVNYTYQpnspfASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVtvgdiVVSSTSKQKEik 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 69 --SPDCLMLFQH-HNLLPWKTINDNIRIGFQQ-KISDEEIN--AQLKLvDLEGRGKHF----PEQLSGGMKQRVALCRAH 138
Cdd:PRK13643 81 pvRKKVGVVFQFpESQLFEETVLKDVAFGPQNfGIPKEKAEkiAAEKL-EMVGLADEFweksPFELSGGQMRRVAIAGIL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRdQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIIS 205
Cdd:PRK13643 160 AMEPEVLVLDEPTAGLDPKARIEMM-QLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKG-HIIS 224
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
10-197 |
5.88e-19 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 85.08 E-value: 5.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCL-----MLFQHHNLLP 83
Cdd:COG3845 14 RFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPrDAIalgigMVHQHFMLVP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 84 WKTINDNIRIGF-------------QQKIsdEEINAQLKL-VDLEGRgkhfPEQLSGGMKQRV----ALCRahvhKPNVI 145
Cdd:COG3845 94 NLTVAENIVLGLeptkggrldrkaaRARI--RELSERYGLdVDPDAK----VEDLSVGEQQRVeilkALYR----GARIL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 146 LMDEPLGAL-----DaftryKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:COG3845 164 ILDEPTAVLtpqeaD-----ELFEILRRLA-AEGKSIIFITHKLREVMAIADRVTVL 214
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
15-209 |
1.36e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 82.75 E-value: 1.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-----------EIKQQPSPDCLML-FQHHNLL 82
Cdd:PRK13645 25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyaipanlkkikEVKRLRKEIGLVFqFPEYQLF 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 83 PwKTINDNIRIGFQQKISDEE-----INAQLKLVDL-EGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK13645 105 Q-ETIEKDIAFGPVNLGENKQeaykkVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDP 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 157 FTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG--CNIISQYEI 209
Cdd:PRK13645 184 KGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGkvISIGSPFEI 238
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-200 |
3.05e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 81.43 E-value: 3.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF--GSHkVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL----- 73
Cdd:PRK13636 5 ILKVEELNYNYsdGTH-ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGLMklres 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 --MLFQH-HNLLPWKTINDNIRIG-FQQKISDEEINAQLKLVdLEGRG----KHFPEQ-LSGGMKQRVALCRAHVHKPNV 144
Cdd:PRK13636 84 vgMVFQDpDNQLFSASVYQDVSFGaVNLKLPEDEVRKRVDNA-LKRTGiehlKDKPTHcLSFGQKKRVAIAGVLVMEPKV 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13636 163 LVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEG 218
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
21-206 |
4.80e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 82.59 E-value: 4.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 21 NLDISKGEIVTFIGKSGCGKSTLLNIIGGFIhPSSGRVIIDN-EIKQQPspdcLMLFQHH------N-LLPWKTINDNIR 92
Cdd:PRK11174 370 NFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGiELRELD----PESWRKHlswvgqNpQLPHGTLRDNVL 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 93 IGfQQKISDEEINAQLKL------VDLEGRGKHFP--EQ---LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAftryk 161
Cdd:PRK11174 445 LG-NPDASDEQLQQALENawvsefLPLLPQGLDTPigDQaagLSVGQAQRLALARALLQPCQLLLLDEPTASLDA----- 518
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2756312332 162 LRDQLVQ--LKHKTES-TIILVAHDIDEaIYLSDRIVLLGEGcNIISQ 206
Cdd:PRK11174 519 HSEQLVMqaLNAASRRqTTLMVTHQLED-LAQWDQIWVMQDG-QIVQQ 564
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-172 |
5.21e-18 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 80.07 E-value: 5.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPspdclmLFQHH 79
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEdITHLP------MHKRA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NL----LP------WK-TINDNIRIGFQ-QKISDEEINAQL-KLVD---LEGRGKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:COG1137 77 RLgigyLPqeasifRKlTVEDNILAVLElRKLSKKEREERLeELLEefgITHLRKSKAYSLSGGERRRVEIARALATNPK 156
|
170 180
....*....|....*....|....*....
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHK 172
Cdd:COG1137 157 FILLDEPFAGVDPIAVADIQKIIRHLKER 185
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
17-200 |
6.39e-18 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 79.72 E-value: 6.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHP----SSGRVIID----NEIKQQpSPDCLMLFQH--HNLLPWKT 86
Cdd:TIGR02770 2 VQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPgltqTSGEILLDgrplLPLSIR-GRHIATIMQNprTAFNPLFT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNIRIGFQQ--KISD---EEINAQLKLVDLEGRG---KHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:TIGR02770 81 MGNHAIETLRSlgKLSKqarALILEALEAVGLPDPEevlKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVN 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 159 RYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR02770 161 QARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDG 202
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-214 |
9.55e-18 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 79.77 E-value: 9.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLfqhHN 80
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQKLYL---DT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWkTINDNIRIgfQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:PRK09544 81 TLPL-TVNRFLRL--RPGTKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQV 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 161 KLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNIISQYEITASHP 214
Cdd:PRK09544 158 ALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHP 211
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
17-200 |
1.00e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 79.80 E-value: 1.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVI-----IDNEIKQQPSPDCLMLFQH-HNLLPWKTINDN 90
Cdd:PRK13648 25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFynnqaITDDNFEKLRKHIGIVFQNpDNQFVGSIVKYD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGFQQ-----KISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQ 165
Cdd:PRK13648 105 VAFGLENhavpyDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDL 184
|
170 180 190
....*....|....*....|....*....|....*
gi 2756312332 166 LVQLKHKTESTIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:PRK13648 185 VRKVKSEHNITIISITHDLSEAME-ADHVIVMNKG 218
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-200 |
1.40e-17 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 78.22 E-value: 1.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSH--KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDC---LML 75
Cdd:cd03369 7 IEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGiDISTIPLEDLrssLTI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPWKTINDNIRIgfQQKISDEEINAQLKLVdlEGrgkhfPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:cd03369 87 IPQDPTLFSGTIRSNLDP--FDEYSDEEIYGALRVS--EG-----GLNLSQGQRQLLCLARALLKRPRVLVLDEATASID 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2756312332 156 AFTryklrDQLVQLKHKTE---STIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03369 158 YAT-----DALIQKTIREEftnSTILTIAHRL-RTIIDYDKILVMDAG 199
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
15-200 |
1.80e-17 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 77.59 E-value: 1.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPS--SGRVIIDNEIKQQPSPDCLMLF--QHHNLLPWKTINDN 90
Cdd:cd03213 23 QLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLgvSGEVLINGRPLDKRSFRKIIGYvpQDDILHPTLTVRET 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRigfqqkisdeeINAQLKlvdlegrgkhfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLK 170
Cdd:cd03213 103 LM-----------FAAKLR-------------GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLA 158
|
170 180 190
....*....|....*....|....*....|.
gi 2756312332 171 hKTESTIILVAHDI-DEAIYLSDRIVLLGEG 200
Cdd:cd03213 159 -DTGRTIICSIHQPsSEIFELFDKLLLLSQG 188
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
22-194 |
2.03e-17 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 79.78 E-value: 2.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 22 LDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL--------MLFQ--HHNLLPWKTINDNI 91
Cdd:COG4608 39 FDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELrplrrrmqMVFQdpYASLNPRMTVGDII 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 92 RIGFQ-QKISD-----EEINAQLKLVDLegRGKH---FPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDaftrYKL 162
Cdd:COG4608 119 AEPLRiHGLASkaerrERVAELLELVGL--RPEHadrYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALD----VSI 192
|
170 180 190
....*....|....*....|....*....|....*.
gi 2756312332 163 RDQ----LVQLKHKTESTIILVAHDIDEAIYLSDRI 194
Cdd:COG4608 193 QAQvlnlLEDLQDELGLTYLFISHDLSVVRHISDRV 228
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
33-200 |
2.17e-17 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 79.06 E-value: 2.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 33 IGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQ-----QPSPDCLMLFQHhnllPWKTINDNIRIG--------FQQKI 99
Cdd:PRK15112 45 IGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgdysYRSQRIRMIFQD----PSTSLNPRQRISqildfplrLNTDL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 100 SDEE----INAQLKLVDL-EGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTE 174
Cdd:PRK15112 121 EPEQrekqIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQG 200
|
170 180
....*....|....*....|....*.
gi 2756312332 175 STIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK15112 201 ISYIYVTQHLGMMKHISDQVLVMHQG 226
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
1-200 |
2.23e-17 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 79.79 E-value: 2.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKV----IHNFNLDISKGEIVTFIGKSGCGKS-TLLNIIGGFIHPssGRV--------------IID 61
Cdd:PRK11022 3 LLNVDKLSVHFGDESApfraVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYP--GRVmaeklefngqdlqrISE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 62 NEIKQQPSPDCLMLFQHhnllPWKTINDNIRIGFQ------------QKISDEEINAQLKLV---DLEGRGKHFPEQLSG 126
Cdd:PRK11022 81 KERRNLVGAEVAMIFQD----PMTSLNPCYTVGFQimeaikvhqggnKKTRRQRAIDLLNQVgipDPASRLDVYPHQLSG 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 127 GMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11022 157 GMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAG 230
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1-200 |
3.59e-17 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 78.11 E-value: 3.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID-NEIKQQPSPDCLML---- 75
Cdd:PRK11300 5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRgQHIEGLPGHQIARMgvvr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 -FQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVD--------LEgRGKHFPEQ-------------LSGGMKQRVA 133
Cdd:PRK11300 85 tFQHVRLFREMTVIENLLVAQHQQLKTGLFSGLLKTPAfrraeseaLD-RAATWLERvgllehanrqagnLAYGQQRRLE 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 134 LCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11300 164 IARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQG 230
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-200 |
3.67e-17 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 77.47 E-value: 3.67e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQ-----HHFGSHK--VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-----IKQQP 68
Cdd:COG4778 4 LLEVENLSktftlHLQGGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvdLAQAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 69 SPDCLMLFQHHnllpwktindnirIGF-QQ------KISDEEINAQlKLVDL-----EGRGK------HF--PEQL---- 124
Cdd:COG4778 84 PREILALRRRT-------------IGYvSQflrvipRVSALDVVAE-PLLERgvdreEARARarellaRLnlPERLwdlp 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 125 ----SGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTeSTIILVAHDID--EAiyLSDRIVLLG 198
Cdd:COG4778 150 patfSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARG-TAIIGIFHDEEvrEA--VADRVVDVT 226
|
..
gi 2756312332 199 EG 200
Cdd:COG4778 227 PF 228
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-200 |
4.03e-17 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 78.17 E-value: 4.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI----KQQPSPDCL--- 73
Cdd:PRK14246 10 VFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVlyfgKDIFQIDAIklr 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ----MLFQHHNLLPWKTINDNIRIGFQ----------QKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:PRK14246 90 kevgMVFQQPNPFPHLSIYDNIAYPLKshgikekreiKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALA 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLKHktESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK14246 170 LKPKVLLMDEPTSMIDIVNSQAIEKLITELKN--EIAIVIVSHNPQQVARVADYVAFLYNG 228
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
14-206 |
5.59e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 77.90 E-value: 5.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCL--------MLFQH-HNLLP 83
Cdd:PRK13646 20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDiTITHKTKDKYIrpvrkrigMVFQFpESQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 84 WKTINDNIRIG---FQQKISDEEINAQLKLVDLeGRGKHF----PEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK13646 100 EDTVEREIIFGpknFKMNLDEVKNYAHRLLMDL-GFSRDVmsqsPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDP 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 157 FTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQ 206
Cdd:PRK13646 179 QSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEG-SIVSQ 227
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
16-200 |
5.81e-17 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 77.97 E-value: 5.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMlfqhhnllPwKTINDNIRIGF 95
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRISFSSQFSWIM--------P-GTIKENIIFGV 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 96 QQkisDE-EINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLR 163
Cdd:cd03291 123 SY---DEyRYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEIF 199
|
170 180 190
....*....|....*....|....*....|....*..
gi 2756312332 164 DQLVqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03291 200 ESCV-CKLMANKTRILVTSKM-EHLKKADKILILHEG 234
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
16-206 |
6.62e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 77.92 E-value: 6.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHP---SSGRVIIDN---------EIKQQPSpdclMLFQH-HNLL 82
Cdd:PRK13640 22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnPNSKITVDGitltaktvwDIREKVG----IVFQNpDNQF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 83 PWKTINDNIRIGFQQK-ISDEE----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAF 157
Cdd:PRK13640 98 VGATVGDDVAFGLENRaVPRPEmikiVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPA 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 158 TRYKLRDQLVQLKHKTESTIILVAHDIDEAIyLSDRIVLLGEGcNIISQ 206
Cdd:PRK13640 178 GKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDG-KLLAQ 224
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
19-205 |
8.19e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 77.48 E-value: 8.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN----------EIKQQPSPDCLmLFQH-HNLLPWKTI 87
Cdd:PRK13649 25 DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDtlitstsknkDIKQIRKKVGL-VFQFpESQLFEETV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 NDNIRIGFQQ-KISDEEINA----QLKLV----DLEGRGkhfPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:PRK13649 104 LKDVAFGPQNfGVSQEEAEAlareKLALVgiseSLFEKN---PFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2756312332 159 RYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNIIS 205
Cdd:PRK13649 181 RKELMTLFKKL-HQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLS 226
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
5-206 |
1.51e-16 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 76.56 E-value: 1.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 5 QQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQPSPDC---LMLFQHHN 80
Cdd:PRK10253 11 EQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEhIQHYASKEVarrIGLLAQNA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWK-TINDNIRIG-------FQ--QKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:PRK10253 91 TTPGDiTVQELVARGryphqplFTrwRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEP 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 151 LGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQ 206
Cdd:PRK10253 171 TTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREG-KIVAQ 225
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
10-195 |
3.51e-16 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 77.17 E-value: 3.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFG---SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN----EIKQQpS--------PDCLM 74
Cdd:COG5265 364 SFGydpERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGqdirDVTQA-SlraaigivPQDTV 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFqhhNllpwKTINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRVALCRAHVHKPN 143
Cdd:COG5265 443 LF---N----DTIAYNIAYG-RPDASEEEVEAAARAAQIHDFIESLPDGydtrvgerglkLSGGEKQRVAIARTLLKNPP 514
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQL-KHKTesTIIlVAH------DIDEAIYLSD-RIV 195
Cdd:COG5265 515 ILIFDEATSALDSRTERAIQAALREVaRGRT--TLV-IAHrlstivDADEILVLEAgRIV 571
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
12-203 |
3.66e-16 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 77.31 E-value: 3.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID-NEIK---------------QQPspdclML 75
Cdd:PRK13657 346 NSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDgTDIRtvtraslrrniavvfQDA-----GL 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQhhnllpwKTINDNIRIGfQQKISDEEINAQLK--------LVDLEGRGKHFPE---QLSGGMKQRVALCRAHVHKPNV 144
Cdd:PRK13657 421 FN-------RSIEDNIRVG-RPDATDEEMRAAAEraqahdfiERKPDGYDTVVGErgrQLSGGERQRLAIARALLKDPPI 492
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIIlvAH---DIDEAiylsDRIVLLGEGCNI 203
Cdd:PRK13657 493 LILDEATSALDVETEAKVKAALDELMKGRTTFII--AHrlsTVRNA----DRILVFDNGRVV 548
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
19-156 |
4.35e-16 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 73.93 E-value: 4.35e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE--IKQQPSPDCLMLFQHH--NLLPWKTINDNIRig 94
Cdd:TIGR01189 18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTplAEQRDEPHENILYLGHlpGLKPELSALENLH-- 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 95 FQQKISDEE---INAQLKLVDLEGRgKHFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:TIGR01189 96 FWAAIHGGAqrtIEDALAAVGLTGF-EDLPaAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDK 160
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-200 |
5.31e-16 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 75.04 E-value: 5.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-----------IKQQPS 69
Cdd:PRK13638 1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKpldyskrgllaLRQQVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 70 pdclMLFQHHNLLPWKT-INDNIRIGFQQ-KISDEEI----NAQLKLVDLEgRGKHFPEQ-LSGGMKQRVALCRAHVHKP 142
Cdd:PRK13638 81 ----TVFQDPEQQIFYTdIDSDIAFSLRNlGVPEAEItrrvDEALTLVDAQ-HFRHQPIQcLSHGQKKRVAIAGALVLQA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 143 NVILMDEPLGALDAFTRYKL----RDQLVQLKHktestIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13638 156 RYLLLDEPTAGLDPAGRTQMiaiiRRIVAQGNH-----VIISSHDIDLIYEISDAVYVLRQG 212
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
23-199 |
6.67e-16 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 74.37 E-value: 6.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 23 DISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI----KQQPSPDCLMLFQhhNLLPWKTINDNIRIGFQQk 98
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTvsykPQYIKADYEGTVR--DLLSSITKDFYTHPYFKT- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 99 isdeEINAQLKLVDLEGRgkHFPEqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTII 178
Cdd:cd03237 98 ----EIAKPLQIEQILDR--EVPE-LSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENNEKTAF 170
|
170 180
....*....|....*....|..
gi 2756312332 179 LVAHDIDEAIYLSDR-IVLLGE 199
Cdd:cd03237 171 VVEHDIIMIDYLADRlIVFEGE 192
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
22-200 |
9.34e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 74.39 E-value: 9.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 22 LDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRV-----IIDNEIKQQPSPDCLMLFQH-HNLLPWKTINDN----- 90
Cdd:PRK13647 26 LSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVkvmgrEVNAENEKWVRSKVGLVFQDpDDQVFSSTVWDDvafgp 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLk 170
Cdd:PRK13647 106 VNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRL- 184
|
170 180 190
....*....|....*....|....*....|
gi 2756312332 171 HKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13647 185 HNQGKTVIVATHDVDLAAEWADQVIVLKEG 214
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
19-196 |
1.12e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 74.48 E-value: 1.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRV-IIDNEIKQQPSPDCL--------MLFQH-HNLLPWKTIN 88
Cdd:PRK13641 25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTItIAGYHITPETGNKNLkklrkkvsLVFQFpEAQLFENTVL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIR-----IGFQQKISDEEINAQLKLVDL-EGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKL 162
Cdd:PRK13641 105 KDVEfgpknFGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEM 184
|
170 180 190
....*....|....*....|....*....|....*
gi 2756312332 163 RDQLVQLKhKTESTIILVAHDIDE-AIYLSDRIVL 196
Cdd:PRK13641 185 MQLFKDYQ-KAGHTVILVTHNMDDvAEYADDVLVL 218
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
12-156 |
1.13e-15 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 72.91 E-value: 1.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-IKQQ-PSPDCLMLF-QHHN-----LLP 83
Cdd:PRK13538 12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEpIRRQrDEYHQDLLYlGHQPgikteLTA 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 84 WKTINDNIRIgfQQKISDEEINAQLKLVDLEGRgKHFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK13538 92 LENLRFYQRL--HGPGDDEALWEALAQVGLAGF-EDVPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDK 162
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
24-200 |
1.31e-15 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 75.69 E-value: 1.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 24 ISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSS--GRVIIDN-EIKQQPSPDCLMLFQHHNLLPWKTINDNI--------- 91
Cdd:PLN03211 91 ASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNrKPTKQILKRTGFVTQDDILYPHLTVRETLvfcsllrlp 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 92 -RIGFQQKIS-DEEINAQLKLVDLEGR--GKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLV 167
Cdd:PLN03211 171 kSLTKQEKILvAESVISELGLTKCENTiiGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLG 250
|
170 180 190
....*....|....*....|....*....|....
gi 2756312332 168 QLKHKTEsTIILVAHDIDEAIY-LSDRIVLLGEG 200
Cdd:PLN03211 251 SLAQKGK-TIVTSMHQPSSRVYqMFDSVLVLSEG 283
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
10-216 |
1.51e-15 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 75.44 E-value: 1.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 10 HFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCL---MLF-----QHHN 80
Cdd:COG1129 261 GLSVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPrDAIragIAYvpedrKGEG 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWKTINDNIRIGFQQKIS----------DEEINAQLKLVDLEGRGkhfPEQ----LSGGMKQRVALCRAHVHKPNVIL 146
Cdd:COG1129 341 LVLDLSIRENITLASLDRLSrgglldrrreRALAEEYIKRLRIKTPS---PEQpvgnLSGGNQQKVVLAKWLATDPKVLI 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 147 MDEPlgaldafTR----------YKLRDQLVQlkhktE-STIILVAHDIDEAIYLSDRIVLLGEGcniisqyEITASHPR 215
Cdd:COG1129 418 LDEP-------TRgidvgakaeiYRLIRELAA-----EgKAVIVISSELPELLGLSDRILVMREG-------RIVGELDR 478
|
.
gi 2756312332 216 S 216
Cdd:COG1129 479 E 479
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-200 |
2.06e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 73.48 E-value: 2.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPS--PDCLML-- 75
Cdd:PRK13644 1 MIRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSklQGIRKLvg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 --FQH-HNLLPWKTINDNIRIGFQQK-ISDEEINaqlKLVD-------LEGRGKHFPEQLSGGMKQRVALCRAHVHKPNV 144
Cdd:PRK13644 81 ivFQNpETQFVGRTVEEDLAFGPENLcLPPIEIR---KRVDralaeigLEKYRHRSPKTLSGGQGQCVALAGILTMEPEC 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDIDEaIYLSDRIVLLGEG 200
Cdd:PRK13644 158 LIFDEVTSMLDPDSGIAVLERIKKL-HEKGKTIVYITHNLEE-LHDADRIIVMDRG 211
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-200 |
4.17e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 73.20 E-value: 4.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSH-----KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRV-IIDNEIKQQPSPDCLML 75
Cdd:PRK13651 3 IKVKNIVKIFNKKlptelKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIeWIFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPwKTINDNI--------RIG----------FQQKI-------------SDEEINAQ----LKLVDL-EGRGKH 119
Cdd:PRK13651 83 VLEKLVIQ-KTRFKKIkkikeirrRVGvvfqfaeyqlFEQTIekdiifgpvsmgvSKEEAKKRaakyIELVGLdESYLQR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 120 FPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGE 199
Cdd:PRK13651 162 SPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNL-NKQGKTIILVTHDLDNVLEWTKRTIFFKD 240
|
.
gi 2756312332 200 G 200
Cdd:PRK13651 241 G 241
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-200 |
7.39e-15 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 73.21 E-value: 7.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHK-VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL-----ML 75
Cdd:PRK10790 341 IDIDNVSFAYRDDNlVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLrqgvaMV 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQHHNLLPwKTINDNIRIGfqQKISDEEINAQLKLVDLEGRGKHFP--------EQ---LSGGMKQRVALCRAHVHKPNV 144
Cdd:PRK10790 421 QQDPVVLA-DTFLANVTLG--RDISEEQVWQALETVQLAELARSLPdglytplgEQgnnLSVGQKQLLALARVLVQTPQI 497
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLKHKTesTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:PRK10790 498 LILDEATANIDSGTEQAIQQALAAVREHT--TLVVIAHRL-STIVEADTILVLHRG 550
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
17-200 |
1.15e-14 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 70.44 E-value: 1.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLL-----PW---KTIN 88
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAyaaqkPWllnATVE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIG--FQQKISDEEINAQLKLVDLE----GRGKHFPEQ---LSGGMKQRVALCRAHVHKPNVILMDEPLGALDA-FT 158
Cdd:cd03290 97 ENITFGspFNKQRYKAVTDACSLQPDIDllpfGDQTEIGERginLSGGQRQRICVARALYQNTNIVFLDDPFSALDIhLS 176
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 159 RYKLRDQLVQLKHKTESTIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:cd03290 177 DHLMQEGILKFLQDDKRTLVLVTHKLQYLPH-ADWIIAMKDG 217
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
16-200 |
2.99e-14 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 71.87 E-value: 2.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSpdclmlfqhhnlLPW---KTINDNIR 92
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISFSPQ------------TSWimpGTIKDNII 508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 93 IGFQQkisDE-EINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:TIGR01271 509 FGLSY---DEyRYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEK 585
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2756312332 161 KLRDQLVqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:TIGR01271 586 EIFESCL-CKLMSNKTRILVTSKL-EHLKKADKILLLHEG 623
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-200 |
4.48e-14 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 70.64 E-value: 4.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---------EIKQQPSP- 70
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGddvealsarAASRRVASv 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 --DCLMLFQHhnllpwkTINDNIRIG-------FQQKISDEE--INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:PRK09536 83 pqDTSLSFEF-------DVRQVVEMGrtphrsrFDTWTETDRaaVERAMERTGVAQFADRPVTSLSGGERQRVLLARALA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 140 HKPNVILMDEPLGALDafTRYKLRD-QLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK09536 156 QATPVLLLDEPTASLD--INHQVRTlELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADG 215
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
20-185 |
5.99e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 68.29 E-value: 5.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDisKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI--KQQPSPDCLMLFQHH------------NLLPWK 85
Cdd:cd03231 21 FTLA--AGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPldFQRDSIARGLLYLGHapgikttlsvleNLRFWH 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINdnirigfqqkiSDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQ 165
Cdd:cd03231 99 ADH-----------SDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEA 167
|
170 180
....*....|....*....|
gi 2756312332 166 LVQlkHKTESTIILVAHDID 185
Cdd:cd03231 168 MAG--HCARGGMVVLTTHQD 185
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-200 |
8.44e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 69.06 E-value: 8.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHF-GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE------IKQQPSPDCL 73
Cdd:PRK13652 3 LIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEpitkenIREVRKFVGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIRIGFQQKISDEE-----INAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:PRK13652 83 VFQNPDDQIFSPTVEQDIAFGPINLGLDEEtvahrVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13652 163 EPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKG 214
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
17-184 |
9.37e-14 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 69.37 E-value: 9.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKS-TLLNIIG-----GFIHPSS---GRVII---DNEIKQQPSPDCLMLFQHhnllPW 84
Cdd:PRK09473 32 VNDLNFSLRAGETLGIVGESGSGKSqTAFALMGllaanGRIGGSAtfnGREILnlpEKELNKLRAEQISMIFQD----PM 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGFQ--------QKISDEE-INAQLKLVDL------EGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK09473 108 TSLNPYMRVGEQlmevlmlhKGMSKAEaFEESVRMLDAvkmpeaRKRMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADE 187
|
170 180 190
....*....|....*....|....*....|....*
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDI 184
Cdd:PRK09473 188 PTTALDVTVQAQIMTLLNELKREFNTAIIMITHDL 222
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
13-182 |
1.11e-13 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 66.79 E-value: 1.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 13 SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIdneikqqPSPDCLMLFQHHNLLPWKTINDNIR 92
Cdd:cd03223 13 GRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM-------PEGEDLLFLPQRPYLPLGTLREQLI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 93 igfqqkisdeeinaqlklvdlegrgkhFP--EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAftryKLRDQLVQLK 170
Cdd:cd03223 86 ---------------------------YPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDE----ESEDRLYQLL 134
|
170
....*....|..
gi 2756312332 171 HKTESTIILVAH 182
Cdd:cd03223 135 KELGITVISVGH 146
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
17-200 |
1.24e-13 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 69.97 E-value: 1.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPdclmlfqhhnllPW---KTINDNIRI 93
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGSVAYVPQQ------------AWiqnDSLRENILF 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 94 G--FQQKISDEEINAQLKLVDLE----GRGKHFPEQ---LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRD 164
Cdd:TIGR00957 722 GkaLNEKYYQQVLEACALLPDLEilpsGDRTEIGEKgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFE 801
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 165 QLV----QLKHKTEstiILVAHDIDeaiYL--SDRIVLLGEG 200
Cdd:TIGR00957 802 HVIgpegVLKNKTR---ILVTHGIS---YLpqVDVIIVMSGG 837
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
15-183 |
1.36e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 69.58 E-value: 1.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGrviidnEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIG 94
Cdd:TIGR03719 19 EILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG------EARPQPGIKVGYLPQEPQLDPTKTVRENVEEG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 95 FQQKISD----EEINA---------------QLKLVD-LEGRGKH--------------FP------EQLSGGMKQRVAL 134
Cdd:TIGR03719 93 VAEIKDAldrfNEISAkyaepdadfdklaaeQAELQEiIDAADAWdldsqleiamdalrCPpwdadvTKLSGGERRRVAL 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 135 CRAHVHKPNVILMDEPLGALDAFTRYKLRDQLvqlkHKTESTIILVAHD 183
Cdd:TIGR03719 173 CRLLLSKPDMLLLDEPTNHLDAESVAWLERHL----QEYPGTVVAVTHD 217
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
7-200 |
1.71e-13 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 69.33 E-value: 1.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 7 LQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTL-LNIIGgfIHPSSGRVIIDNeikqQPspdcLMLFQHHNLLPWK 85
Cdd:COG4172 292 FRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLR--LIPSEGEIRFDG----QD----LDGLSRRALRPLR 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 ------------------TINDNIRIGF---QQKISDEEINAQ----LKLVDLEGRGKH-FPEQLSGGMKQRVALCRAHV 139
Cdd:COG4172 362 rrmqvvfqdpfgslsprmTVGQIIAEGLrvhGPGLSAAERRARvaeaLEEVGLDPAARHrYPHEFSGGQRQRIAIARALI 441
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 140 HKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4172 442 LEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDG 502
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-183 |
1.79e-13 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 69.33 E-value: 1.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHK----VIHNFNLDISKGEIVTFIGKSGCGKS-TLLNIIG----GFIHPsSGRVIIDNEIKQQPSPD 71
Cdd:COG4172 6 LLSVEDLSVAFGQGGgtveAVKGVSFDIAAGETLALVGESGSGKSvTALSILRllpdPAAHP-SGSILFDGQDLLGLSER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CL---------MLFQH--HNLLPWKTINDNIR--IGFQQKISDEEINAQ----LKLV---DLEGRGKHFPEQLSGGMKQR 131
Cdd:COG4172 85 ELrrirgnriaMIFQEpmTSLNPLHTIGKQIAevLRLHRGLSGAAARARalelLERVgipDPERRLDAYPHQLSGGQRQR 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 132 VALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHD 183
Cdd:COG4172 165 VMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHD 216
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
17-201 |
3.30e-13 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 68.51 E-value: 3.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---------EIKQQpspdCLMLFQHHNLLPwKTI 87
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGhdlrdytlaSLRNQ----VALVSQNVHLFN-DTI 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 NDNIRIGFQQKISDEEINAQLKL---VDLEGRGKH-----FPEQ---LSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK11176 434 ANNIAYARTEQYSREQIEEAARMayaMDFINKMDNgldtvIGENgvlLSGGQRQRIAIARALLRDSPILILDEATSALDT 513
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2756312332 157 FTRYKLRDQLVQLkhKTESTIILVAHDIdEAIYLSDRIVLLGEGC 201
Cdd:PRK11176 514 ESERAIQAALDEL--QKNRTSLVIAHRL-STIEKADEILVVEDGE 555
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-205 |
3.38e-13 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 68.27 E-value: 3.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL------M 74
Cdd:PRK09700 5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAaqlgigI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIG--FQQKI--------SDEEINAQ--LKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKP 142
Cdd:PRK09700 85 IYQELSVIDELTVLENLYIGrhLTKKVcgvniidwREMRVRAAmmLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEGCNIIS 205
Cdd:PRK09700 165 KVIIMDEPTSSLTNKEVDYLFLIMNQLR-KEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCS 226
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
16-156 |
3.39e-13 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 66.44 E-value: 3.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEikQQPSPDCLMLFQ---HHNLL-PWKTINDNI 91
Cdd:PRK13539 17 LFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGG--DIDDPDVAEACHylgHRNAMkPALTVAENL 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 92 RigFQQKI---SDEEINAQLKLVDLEGRGkHFPEQ-LSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK13539 95 E--FWAAFlggEELDIAAALEAVGLAPLA-HLPFGyLSAGQKRRVALARLLVSNRPIWILDEPTAALDA 160
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
20-155 |
3.40e-13 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 67.68 E-value: 3.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDisKGEIVTFIGKSGCGKSTL---LNIIGgfiHPSSGRVIIDNEIKQQPSPDCL--------MLFQHhnllPWKTIN 88
Cdd:PRK11308 36 FTLE--RGKTLAVVGESGCGKSTLarlLTMIE---TPTGGELYYQGQDLLKADPEAQkllrqkiqIVFQN----PYGSLN 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGFqqkISDE--EINAQL-------------KLVDLegRGKH---FPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:PRK11308 107 PRKKVGQ---ILEEplLINTSLsaaerrekalammAKVGL--RPEHydrYPHMFSGGQRQRIAIARALMLDPDVVVADEP 181
|
....*
gi 2756312332 151 LGALD 155
Cdd:PRK11308 182 VSALD 186
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
3-207 |
4.17e-13 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 66.14 E-value: 4.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 3 KIQQLQHHFG------SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFI--HPSSGRVIIDNEikqQPSPDCLM 74
Cdd:COG2401 26 RVAIVLEAFGvelrvvERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDN---QFGREASL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LfqhHNLLPWKTINDNIRIGFQQKISDeeinAQLKLvdlegrgKHFPEqLSGGMKQRVALCRAHVHKPNVILMDEPLGAL 154
Cdd:COG2401 103 I---DAIGRKGDFKDAVELLNAVGLSD----AVLWL-------RRFKE-LSTGQKFRFRLALLLAERPKLLVIDEFCSHL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 155 DAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLS-DRIVLLGEGCNIISQY 207
Cdd:COG2401 168 DRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQpDLLIFVGYGGVPEEKR 221
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
15-209 |
4.20e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 67.57 E-value: 4.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVII-DNEIKQQPSPDCL-------------------- 73
Cdd:PRK13631 40 VALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgDIYIGDKKNNHELitnpyskkiknfkelrrrvs 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWK-TINDNIRIG---FQQKISDEEINAQLKLVDLeGRGKHF----PEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:PRK13631 120 MVFQFPEYQLFKdTIEKDIMFGpvaLGVKKSEAKKLAKFYLNKM-GLDDSYlersPFGLSGGQKRRVAIAGILAIQPEIL 198
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 146 LMDEPLGALDAFTRYKLRdQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGCNIIS--QYEI 209
Cdd:PRK13631 199 IFDEPTAGLDPKGEHEMM-QLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTgtPYEI 263
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
12-200 |
4.91e-13 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 67.81 E-value: 4.91e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKST----LLNIIggfihPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTI 87
Cdd:PRK15134 297 DHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLHNLNRRQLLPVRHRIQVVFQDP 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 88 ND--NIRIGFQQKIS---------------DEEINAQLKLVDLEGRGKH-FPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK15134 372 NSslNPRLNVLQIIEeglrvhqptlsaaqrEQQVIAVMEEVGLDPETRHrYPAEFSGGQRQRIAIARALILKPSLIILDE 451
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK15134 452 PTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQG 502
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
14-197 |
6.45e-13 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 66.44 E-value: 6.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRViidnEIKQQPSPDCLmlfqHHNLLPWKTINDNIRI 93
Cdd:PRK15056 20 HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKI----SILGQPTRQAL----QKNLVAYVPQSEEVDW 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 94 GFQQKISD---------------------EEINAQLKLVD-LEGRGKHFPEqLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:PRK15056 92 SFPVLVEDvvmmgryghmgwlrrakkrdrQIVTAALARVDmVEFRHRQIGE-LSGGQKKRVFLARAIAQQGQVILLDEPF 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 152 GALDAFTRYKLRDQLVQLKHKTEsTIILVAHDIDEAIYLSDRIVLL 197
Cdd:PRK15056 171 TGVDVKTEARIISLLRELRDEGK-TMLVSTHNLGSVTEFCDYTVMV 215
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
5-200 |
7.42e-13 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 66.07 E-value: 7.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 5 QQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-----------------IKQQ 67
Cdd:PRK10895 7 KNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEdisllplhararrgigyLPQE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 68 PSpdclmLFQ----HHNLLPWKTINDNIRIGfQQKISDEEINAQLKLVDLEgrgKHFPEQLSGGMKQRVALCRAHVHKPN 143
Cdd:PRK10895 87 AS-----IFRrlsvYDNLMAVLQIRDDLSAE-QREDRANELMEEFHIEHLR---DSMGQSLSGGERRRVEIARALAANPK 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 144 VILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIIlVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10895 158 FILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLI-TDHNVRETLAVCERAYIVSQG 213
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-200 |
7.53e-13 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 67.57 E-value: 7.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKST-------LLNIIGGFIHPSS------GRVII------DNEIKQQPSPDCLMLFQ 77
Cdd:PRK10261 32 VRNLSFSLQRGETLAIVGESGSGKSVtalalmrLLEQAGGLVQCDKmllrrrSRQVIelseqsAAQMRHVRGADMAMIFQ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 H--HNLLPWKTINDNI--RIGFQQKISDEEINA-------QLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVIL 146
Cdd:PRK10261 112 EpmTSLNPVFTVGEQIaeSIRLHQGASREEAMVeakrmldQVRIPEAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 147 MDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10261 192 ADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQG 245
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
13-200 |
8.65e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 67.69 E-value: 8.65e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 13 SHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLN-IIGGFIHPSSGRVIIDNEIKQQPSpdclmlfqhhnlLPW---KTIN 88
Cdd:PLN03232 629 SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSVVIRGSVAYVPQ------------VSWifnATVR 696
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGfqqkiSDEEINAQLKLVDLEG--------RGKHFPE------QLSGGMKQRVALCRAHVHKPNVILMDEPLGAL 154
Cdd:PLN03232 697 ENILFG-----SDFESERYWRAIDVTAlqhdldllPGRDLTEigergvNISGGQKQRVSMARAVYSNSDIYIFDDPLSAL 771
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2756312332 155 DAFTRYKLRDQLVQ--LKHKTEstiILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:PLN03232 772 DAHVAHQVFDSCMKdeLKGKTR---VLVTNQL-HFLPLMDRIILVSEG 815
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
11-200 |
1.31e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 65.89 E-value: 1.31e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNI-------IGGFIHPSS----GRVIIDNEIKQQPSPDCLMLFQHH 79
Cdd:PRK14271 31 FAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTlnrmndkVSGYRYSGDvllgGRSIFNYRDVLEFRRRVGMLFQRP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NLLPwKTINDNIRIGFQ--QKISDEEIN--AQLKLVDL------EGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK14271 111 NPFP-MSIMDNVLAGVRahKLVPRKEFRgvAQARLTEVglwdavKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDE 189
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTesTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK14271 190 PTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDG 238
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
26-196 |
1.73e-12 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 63.16 E-value: 1.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 26 KGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIdneikqqpspdclmlfqhhnllpwktindnirigfqqkISDEEIN 105
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY--------------------------------------IDGEDIL 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 106 AQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRD-----QLVQLKHKTESTIILV 180
Cdd:smart00382 43 EEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrLLLLLKSEKNLTVILT 122
|
170
....*....|....*.
gi 2756312332 181 AHDIDEAIYLSDRIVL 196
Cdd:smart00382 123 TNDEKDLGPALLRRRF 138
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
16-206 |
3.27e-12 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 64.42 E-value: 3.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI-----------------KQQPSPDCLMLFQH 78
Cdd:PRK10575 26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPleswsskafarkvaylpQQLPAAEGMTVREL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNL--LPWKTINDNIRIGFQQKIsDEEINaqlkLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK10575 106 VAIgrYPWHGALGRFGAADREKV-EEAIS----LVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 157 FTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLgEGCNIISQ 206
Cdd:PRK10575 181 AHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVAL-RGGEMIAQ 229
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
19-200 |
3.50e-12 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 65.91 E-value: 3.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHP-SSGRVIIDNEIKQQPSpdclmlfqhhnlLPW---KTINDNIRIG 94
Cdd:PLN03130 635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPrSDASVVIRGTVAYVPQ------------VSWifnATVRDNILFG 702
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 95 --FQQKISDEEINA---QLKLVDLEG--------RGKHfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:PLN03130 703 spFDPERYERAIDVtalQHDLDLLPGgdlteigeRGVN----ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQ 778
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 162 LRDQLV--QLKHKTEstiILVAHDIDeaiYLS--DRIVLLGEG 200
Cdd:PLN03130 779 VFDKCIkdELRGKTR---VLVTNQLH---FLSqvDRIILVHEG 815
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
20-200 |
3.56e-12 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 64.09 E-value: 3.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIhPSSGRVIIDNEIKQQPSPDCL-----MLFQHHNLLPWKTINDNIRIG 94
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDWSAAELarhraYLSQQQSPPFAMPVFQYLALH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 95 FQQKISDEEINA-------QLKLVDLEGRGKHfpeQLSGGMKQRVALCRA--HVHkPNV------ILMDEPLGALD---- 155
Cdd:COG4138 94 QPAGASSEAVEQllaqlaeALGLEDKLSRPLT---QLSGGEWQRVRLAAVllQVW-PTInpegqlLLLDEPMNSLDvaqq 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 156 -AFtrYKLRDQLVQLKhkteSTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG4138 170 aAL--DRLLRELCQQG----ITVVMSSHDLNHTLRHADRVWLLKQG 209
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
11-183 |
3.63e-12 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 65.36 E-value: 3.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIK----QQPSPDCL------------- 73
Cdd:PRK11147 13 FSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIvarlQQDPPRNVegtvydfvaegie 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 ----MLFQHHNLLPW-------KTINDNIRIgfQQKIS-------DEEINAQLKLVDLEGRGKHfpEQLSGGMKQRVALC 135
Cdd:PRK11147 93 eqaeYLKRYHDISHLvetdpseKNLNELAKL--QEQLDhhnlwqlENRINEVLAQLGLDPDAAL--SSLSGGWLRKAALG 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2756312332 136 RAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKhkteSTIILVAHD 183
Cdd:PRK11147 169 RALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQ----GSIIFISHD 212
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
64-197 |
4.77e-12 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 65.44 E-value: 4.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 64 IKQQPspdclMLFQhhnllpwKTINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRV 132
Cdd:PTZ00265 1301 VSQEP-----MLFN-------MSIYENIKFG-KEDATREDVKRACKFAAIDEFIESLPNKydtnvgpygksLSGGQKQRI 1367
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2756312332 133 ALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIdEAIYLSDRIVLL 197
Cdd:PTZ00265 1368 AIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRI-ASIKRSDKIVVF 1431
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
8-200 |
5.81e-12 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 62.67 E-value: 5.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 8 QHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPS---SGRVIIDN----EIKQQPSPDCLMLFQHHN 80
Cdd:cd03233 14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGipykEFAEKYPGEIIYVSEEDV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWKTINDNIRIGfqqkisdeeinaqlklvdLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:cd03233 94 HFPTLTVRETLDFA------------------LRCKGNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTAL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 161 KLRDQLVQLKHKTESTIILVAHDIDEAIY-LSDRIVLLGEG 200
Cdd:cd03233 156 EILKCIRTMADVLKTTTFVSLYQASDEIYdLFDKVLVLYEG 196
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-166 |
6.58e-12 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 64.57 E-value: 6.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIK----QQpspdclmlfQ 77
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETVKlayvDQ---------S 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWKTI-------NDNIRIGfqqkisDEEINA-------------QLKLVDlegrgkhfpeQLSGGMKQRVALCRA 137
Cdd:TIGR03719 394 RDALDPNKTVweeisggLDIIKLG------KREIPSrayvgrfnfkgsdQQKKVG----------QLSGGERNRVHLAKT 457
|
170 180
....*....|....*....|....*....
gi 2756312332 138 HVHKPNVILMDEPLGALDAFTRYKLRDQL 166
Cdd:TIGR03719 458 LKSGGNVLLLDEPTNDLDVETLRALEEAL 486
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
15-200 |
7.24e-12 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 64.55 E-value: 7.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCL-----MLFQHHNLLPWKTIN 88
Cdd:PRK11288 18 KALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTtAALaagvaIIYQELHLVPEMTVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIG-FQQK---ISDEEINAQLKLvDLEGRGKHF-PEQ----LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAftR 159
Cdd:PRK11288 98 ENLYLGqLPHKggiVNRRLLNYEARE-QLEHLGVDIdPDTplkyLSIGQRQMVEIAKALARNARVIAFDEPTSSLSA--R 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2756312332 160 -----YKLRDQLvqlkhKTESTIIL-VAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11288 175 eieqlFRVIREL-----RAEGRVILyVSHRMEEIFALCDAITVFKDG 216
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
21-200 |
7.42e-12 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 64.61 E-value: 7.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 21 NLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDC-----------LMLFQHhnLLpwktind 89
Cdd:PRK10522 343 NLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDyrklfsavftdFHLFDQ--LL------- 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 90 niriGFQQKISDEEIN----AQLKL---VDLEGrGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEplGALDA---FTR 159
Cdd:PRK10522 414 ----GPEGKPANPALVekwlERLKMahkLELED-GRISNLKLSKGQKKRLALLLALAEERDILLLDE--WAADQdphFRR 486
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 160 YKLRDQLVQLKHKTEsTIILVAHDiDEAIYLSDRIVLLGEG 200
Cdd:PRK10522 487 EFYQVLLPLLQEMGK-TIFAISHD-DHYFIHADRLLEMRNG 525
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
15-200 |
9.63e-12 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 64.41 E-value: 9.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMlfqhhNllpwKTINDNIrIG 94
Cdd:PTZ00243 674 VLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERSIAYVPQQAWIM-----N----ATVRGNI-LF 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 95 FqqkisDEEINAQL----KLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTR 159
Cdd:PTZ00243 744 F-----DEEDAARLadavRVSQLEADLAQLGGgleteigekgvNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVG 818
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 160 YKLRDQLVqLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:PTZ00243 819 ERVVEECF-LGALAGKTRVLATHQV-HVVPRADYVVALGDG 857
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-200 |
1.02e-11 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 64.11 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKST----LLNII---GGFIHPSSGRVIIDNEIKQQP-SPDCLMLFQ--HHNLLPWKT 86
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTtgraLLRLVesqGGEIIFNGQRIDTLSPGKLQAlRRDIQFIFQdpYASLDPRQT 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 87 INDNI----RIG--FQQKISDEEINAQLKLVDLegRGKH---FPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAF 157
Cdd:PRK10261 420 VGDSImeplRVHglLPGKAAAARVAWLLERVGL--LPEHawrYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVS 497
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 158 TRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10261 498 IRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLG 540
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
20-200 |
1.08e-11 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 62.64 E-value: 1.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIhPSSGRVIIDNE----------------IKQQPSPDCLM-LFQHHNL- 81
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQpleawsaaelarhrayLSQQQTPPFAMpVFQYLTLh 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFqqkisdEEINAQLKLVDLEGRGKHfpeQLSGGMKQRVALCRA--HVHK---PN--VILMDEPLGAL 154
Cdd:PRK03695 94 QPDKTRTEAVASAL------NEVAEALGLDDKLGRSVN---QLSGGEWQRVRLAAVvlQVWPdinPAgqLLLLDEPMNSL 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 155 DaFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK03695 165 D-VAQQAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQG 209
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
4-183 |
1.20e-11 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 63.82 E-value: 1.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 4 IQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKqqpspdcLMLFQHH--NL 81
Cdd:PRK11147 322 MENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLE-------VAYFDQHraEL 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFQqkisDEEINaqlklvdleGRGKH---------FPEQ--------LSGGMKQRVALCRAHVHKPNV 144
Cdd:PRK11147 395 DPEKTVMDNLAEGKQ----EVMVN---------GRPRHvlgylqdflFHPKramtpvkaLSGGERNRLLLARLFLKPSNL 461
|
170 180 190
....*....|....*....|....*....|....*....
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLkhktESTIILVAHD 183
Cdd:PRK11147 462 LILDEPTNDLDVETLELLEELLDSY----QGTVLLVSHD 496
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
2-199 |
3.71e-11 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 60.28 E-value: 3.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNlDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGrviidneikqqpspdclmlfqhhnl 81
Cdd:cd03222 1 QLYPDCVKRYGVFFLLVELG-VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGD------------------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 lpwKTINDNIRIGFQ-QKISdeeinaqlklvdlegrgkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:cd03222 55 ---NDEWDGITPVYKpQYID-----------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRL 108
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2756312332 161 KLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRI-VLLGE 199
Cdd:cd03222 109 NAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIhVFEGE 148
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
1-182 |
3.79e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 60.27 E-value: 3.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFgSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCLMLFQHH 79
Cdd:PRK13541 1 MLSLHQLQFNI-EQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNcNINNIAKPYCTYIGHNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NLLPWKTINDNIRIGFQQKISDEEINAQL---KLVDLEGRGKHfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDA 156
Cdd:PRK13541 80 GLKLEMTVFENLKFWSEIYNSAETLYAAIhyfKLHDLLDEKCY---SLSSGMQKIVAIARLIACQSDLWLLDEVETNLSK 156
|
170 180
....*....|....*....|....*.
gi 2756312332 157 FTRyKLRDQLVQLKHKTESTIILVAH 182
Cdd:PRK13541 157 ENR-DLLNNLIVMKANSGGIVLLSSH 181
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-200 |
4.25e-11 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 61.38 E-value: 4.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFI----HPSSGRVIIDNEIKQQP--SPDCLM 74
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLtgggAPRGARVTGDVTLNGEPlaAIDAPR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWK-------TIND--------NIRIGFQQKISDEEINAQ-LKLVDLEGRGKHFPEQLSGGMKQRVALCR-- 136
Cdd:PRK13547 81 LARLRAVLPQAaqpafafSAREivllgrypHARRAGALTHRDGEIAWQaLALAGATALVGRDVTTLSGGELARVQFARvl 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 137 AHVHK-------PNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13547 161 AQLWPphdaaqpPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADG 231
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
2-216 |
4.66e-11 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 62.12 E-value: 4.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNF-----NLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLM-- 74
Cdd:COG4615 328 LELRGVTYRYPGEDGDEGFtlgpiDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAYRql 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 ---------LFQHhnLLpwktindniriGFQQKISDEEINAQLKLVDLEG----RGKHF-PEQLSGGMKQRVALCRAHV- 139
Cdd:COG4615 408 fsavfsdfhLFDR--LL-----------GLDGEADPARARELLERLELDHkvsvEDGRFsTTDLSQGQRKRLALLVALLe 474
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 140 HKPnVILMDE------PlgaldAFTRYKLRDQLVQLKH--KtesTIILVAHDiDEAIYLSDRIVLLGEGCniISQYEITA 211
Cdd:COG4615 475 DRP-ILVFDEwaadqdP-----EFRRVFYTELLPELKArgK---TVIAISHD-DRYFDLADRVLKMDYGK--LVELTGPA 542
|
....*
gi 2756312332 212 SHPRS 216
Cdd:COG4615 543 ALAAS 547
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
2-196 |
6.05e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 61.97 E-value: 6.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHK---VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE--------------- 63
Cdd:PTZ00265 383 IQFKNVRFHYDTRKdveIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDShnlkdinlkwwrski 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 64 --IKQQPspdclMLFQH-------HNLLPWKTI----------------NDNIRIGFQQK-------------------- 98
Cdd:PTZ00265 463 gvVSQDP-----LLFSNsiknnikYSLYSLKDLealsnyynedgndsqeNKNKRNSCRAKcagdlndmsnttdsneliem 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 99 ------ISDEEINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYK 161
Cdd:PTZ00265 538 rknyqtIKDSEVVDVSKKVLIHDFVSALPDKyetlvgsnaskLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYL 617
|
250 260 270
....*....|....*....|....*....|....*
gi 2756312332 162 LRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVL 196
Cdd:PTZ00265 618 VQKTINNLKGNENRITIIIAHRLSTIRYANTIFVL 652
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
4-183 |
6.43e-11 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 61.83 E-value: 6.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 4 IQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGrviidnEIK-----------QQPSPDC 72
Cdd:PRK15064 322 VENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSG------TVKwsenanigyyaQDHAYDF 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 73 ---LMLF----QhhnllpWKTINDNI--------RIGFqqkiSDEEINAQLKLvdlegrgkhfpeqLSGGMKQRVALCRA 137
Cdd:PRK15064 396 endLTLFdwmsQ------WRQEGDDEqavrgtlgRLLF----SQDDIKKSVKV-------------LSGGEKGRMLFGKL 452
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 138 HVHKPNVILMDEPLGALDAFTRYKLRDQLvqlkHKTESTIILVAHD 183
Cdd:PRK15064 453 MMQKPNVLVMDEPTNHMDMESIESLNMAL----EKYEGTLIFVSHD 494
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
19-199 |
7.37e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 61.36 E-value: 7.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLD-----ISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQP---SPDCLMLFQhhNLLpwKTINDN 90
Cdd:PRK13409 352 DFSLEveggeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKISYKPqyiKPDYDGTVE--DLL--RSITDD 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 91 IRIGFQQkisdEEINAQLKLVDLEGRGKhfpEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLK 170
Cdd:PRK13409 428 LGSSYYK----SEIIKPLQLERLLDKNV---KDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIA 500
|
170 180 190
....*....|....*....|....*....|
gi 2756312332 171 HKTESTIILVAHDIDEAIYLSDR-IVLLGE 199
Cdd:PRK13409 501 EEREATALVVDHDIYMIDYISDRlMVFEGE 530
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-183 |
1.21e-10 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 60.68 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIK------------QQP 68
Cdd:PRK15064 1 MLSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNERlgklrqdqfafeEFT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 69 SPDCLMLfQHHNLlpWKTINDNIRIGFQQKISDEEinaQLKLVDLEGR------------------GKHFP-EQLSGGMK 129
Cdd:PRK15064 81 VLDTVIM-GHTEL--WEVKQERDRIYALPEMSEED---GMKVADLEVKfaemdgytaearagelllGVGIPeEQHYGLMS 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 130 Q-------RVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKhkteSTIILVAHD 183
Cdd:PRK15064 155 EvapgwklRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNERN----STMIIISHD 211
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-150 |
1.53e-10 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 60.91 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfihpssGRVIidneikQQPSPDCL---MLFQH 78
Cdd:NF033858 2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAG------ARKI------QQGRVEVLggdMADAR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 H-----------------NLLPWKTINDNI----RI-GFQQKISDEEINAQLKLVDLEGrgkhFPE----QLSGGMKQRV 132
Cdd:NF033858 70 HrravcpriaympqglgkNLYPTLSVFENLdffgRLfGQDAAERRRRIDELLRATGLAP----FADrpagKLSGGMKQKL 145
|
170
....*....|....*...
gi 2756312332 133 ALCRAHVHKPNVILMDEP 150
Cdd:NF033858 146 GLCCALIHDPDLLILDEP 163
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
27-199 |
2.47e-10 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 58.92 E-value: 2.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 27 GEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRV--------IIDN----------EIKQQPSPDCLMLFQHHNLLPwKTIN 88
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppdwdeILDEfrgselqnyfTKLLEGDVKVIVKPQYVDLIP-KAVK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRdQLVQ 168
Cdd:cd03236 105 GKVGELLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAA-RLIR 183
|
170 180 190
....*....|....*....|....*....|..
gi 2756312332 169 LKHKTESTIILVAHDIDEAIYLSDRI-VLLGE 199
Cdd:cd03236 184 ELAEDDNYVLVVEHDLAVLDYLSDYIhCLYGE 215
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
11-242 |
3.48e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 59.45 E-value: 3.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfIHPS---SGRVIIDNE------IKQQPSPDCLMLFQHHNL 81
Cdd:TIGR02633 11 FGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHgtwDGEIYWSGSplkasnIRDTERAGIVIIHQELTL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFQQKISD------------EEINAQLKLVDLEgrGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:TIGR02633 90 VPELSVAENIFLGNEITLPGgrmaynamylraKNLLRELQLDADN--VTRPVGDYGGGQQQLVEIAKALNKQARLLILDE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTiILVAHDIDEAIYLSDRIVLLGEGC-------------NIISQY---EITASH 213
Cdd:TIGR02633 168 PSSSLTEKETEILLDIIRDLKAHGVAC-VYISHKLNEVKAVCDTICVIRDGQhvatkdmstmsedDIITMMvgrEITSLY 246
|
250 260 270
....*....|....*....|....*....|
gi 2756312332 214 PRSRNDshllkIRNEIMETFALN-HHQVEP 242
Cdd:TIGR02633 247 PHEPHE-----IGDVILEARNLTcWDVINP 271
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-183 |
3.81e-10 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 59.41 E-value: 3.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKqqpspdcLMLFQHHN 80
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIK-------LGYFAQHQ 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 81 LLPWKTinDNIRIGFQQKISDEEINAQLKlvDLEG----RGKHFPE---QLSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:PRK10636 385 LEFLRA--DESPLQHLARLAPQELEQKLR--DYLGgfgfQGDKVTEetrRFSGGEKARLVLALIVWQRPNLLLLDEPTNH 460
|
170 180 190
....*....|....*....|....*....|
gi 2756312332 154 LDAFTRYKLRDQLVQLkhktESTIILVAHD 183
Cdd:PRK10636 461 LDLDMRQALTEALIDF----EGALVVVSHD 486
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
15-149 |
3.98e-10 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 59.38 E-value: 3.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDneikqqpsPDCLMLFqhhnlLPWK------TIN 88
Cdd:TIGR00954 466 VLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKP--------AKGKLFY-----VPQRpymtlgTLR 532
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 89 DNI-----RIGFQQK-ISDEEINAQLKLVDLEG---RGKHFP------EQLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:TIGR00954 533 DQIiypdsSEDMKRRgLSDKDLEQILDNVQLTHileREGGWSavqdwmDVLSGGEKQRIAMARLFYHKPQFAILDE 608
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
17-222 |
4.09e-10 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 58.17 E-value: 4.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKS----TLLNIIGGFIHPSSGRVIIDNE--------------IKQQPSPdclmLFQh 78
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKpvapcalrgrkiatIMQNPRS----AFN- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 hnllPWKTINDNIRIGFQQK---ISDEEINAQLKLVDLEGRG---KHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK10418 94 ----PLHTMHTHARETCLALgkpADDATLTAALEAVGLENAArvlKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTT 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 153 ALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEGcNIISQYEI-----TASHPRSRN--DSHL 222
Cdd:PRK10418 170 DLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHG-RIVEQGDVetlfnAPKHAVTRSlvSAHL 245
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-182 |
4.27e-10 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 58.11 E-value: 4.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfiHPS----------SGRVIIDNEIKQQPSP 70
Cdd:CHL00131 7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAykilegdilfKGESILDLEPEERAHL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 71 DCLMLFQHHNLLPWKTINDNIRIGFQQKISD------------EEINAQLKLVDLEGR--GKHFPEQLSGGMKQRVALCR 136
Cdd:CHL00131 85 GIFLAFQYPIEIPGVSNADFLRLAYNSKRKFqglpeldpleflEIINEKLKLVGMDPSflSRNVNEGFSGGEKKRNEILQ 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2756312332 137 AHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTEStIILVAH 182
Cdd:CHL00131 165 MALLDSELAILDETDSGLDIDALKIIAEGINKLMTSENS-IILITH 209
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
17-200 |
4.41e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 59.25 E-value: 4.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCLmlfqhHNLLPWKTiNDNIRIGF 95
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPqDGL-----ANGIVYIS-EDRKRDGL 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 96 QQKISDEE---INAQLKLVDLEGRGKHFPEQ-----------------------LSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK10762 342 VLGMSVKEnmsLTALRYFSRAGGSLKHADEQqavsdfirlfniktpsmeqaiglLSGGNQQKVAIARGLMTRPKVLILDE 421
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTEStIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10762 422 PTRGVDVGAKKEIYQLINQFKAEGLS-IILVSSEMPEVLGMSDRILVMHEG 471
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
27-200 |
5.52e-10 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 58.91 E-value: 5.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 27 GEIVTFIGKSGCGKSTLLNIIGGFIHPS---SGRVIIDNEI--KQQPSPDCLMLFQHHNLLPWKTINDNI---------- 91
Cdd:TIGR00955 51 GELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPidAKEMRAISAYVQQDDLFIPTLTVREHLmfqahlrmpr 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 92 RIGFQQKISD-EEINAQLKLVD-------LEGRGKhfpeQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYklr 163
Cdd:TIGR00955 131 RVTKKEKRERvDEVLQALGLRKcantrigVPGRVK----GLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAY--- 203
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2756312332 164 dQLVQ-LKHKTES--TIILVAHDIDEAIY-LSDRIVLLGEG 200
Cdd:TIGR00955 204 -SVVQvLKGLAQKgkTIICTIHQPSSELFeLFDKIILMAEG 243
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
12-197 |
7.23e-10 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 57.99 E-value: 7.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfIHPSSGRVIIDNeikqqpspdclMLFQHHNLLPW------K 85
Cdd:COG4170 18 GRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICG-ITKDNWHVTADR-----------FRWNGIDLLKLsprerrK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINDNIRIGFQQKIS----DEEINAQLKLV----DLEGR-------------------G--------KHFPEQLSGGMKQ 130
Cdd:COG4170 86 IIGREIAMIFQEPSScldpSAKIGDQLIEAipswTFKGKwwqrfkwrkkraiellhrvGikdhkdimNSYPHELTEGECQ 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 131 RVALCRAHVHKPNVILMDEPLGALDAFTR---YKLRDQLVQLKHkteSTIILVAHDIDEAIYLSDRIVLL 197
Cdd:COG4170 166 KVMIAMAIANQPRLLIADEPTNAMESTTQaqiFRLLARLNQLQG---TSILLISHDLESISQWADTITVL 232
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
14-200 |
8.75e-10 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 58.38 E-value: 8.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DC----LMLF----QHHNLLPW 84
Cdd:PRK11288 266 PGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPrDAiragIMLCpedrKAEGIIPV 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGFQQKISD---------EEINAQLKLVDLEGRGKHfPEQ----LSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:PRK11288 346 HSVADNINISARRHHLRagclinnrwEAENADRFIRSLNIKTPS-REQlimnLSGGNQQKAILGRWLSEDMKVILLDEPT 424
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 152 GALDAFTR-------YKLRDQLVqlkhktesTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK11288 425 RGIDVGAKheiynviYELAAQGV--------AVLFVSSDLPEVLGVADRIVVMREG 472
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
12-208 |
9.50e-10 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 57.56 E-value: 9.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHpSSGRVIID----NEIKQQP-------SPDCLMLFQ--- 77
Cdd:cd03289 15 GGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDgvswNSVPLQKwrkafgvIPQKVFIFSgtf 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWktindnirigfqQKISDEEINAQLKLVDLEGRGKHFPEQ-----------LSGGMKQRVALCRAHVHKPNVIL 146
Cdd:cd03289 94 RKNLDPY------------GKWSDEEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVLSKAKILL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 147 MDEPLGALDAFTRYKLRDqlvQLKHK-TESTIILVAHDIdEAIYLSDRIVLLGEgcNIISQYE 208
Cdd:cd03289 162 LDEPSAHLDPITYQVIRK---TLKQAfADCTVILSEHRI-EAMLECQRFLVIEE--NKVRQYD 218
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
2-155 |
1.10e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 56.38 E-value: 1.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfiHPS----SGRVIIDNEIKQQPSPD------ 71
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMG--HPKyevtEGEILFKGEDITDLPPEerarlg 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 72 CLMLFQHHNLLPWKTINDNIRigfqqkisdeEINaqlklvdlegrgkhfpEQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:cd03217 79 IFLAFQYPPEIPGVKNADFLR----------YVN----------------EGFSGGEKKRNEILQLLLLEPDLAILDEPD 132
|
....
gi 2756312332 152 GALD 155
Cdd:cd03217 133 SGLD 136
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1-155 |
1.10e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 56.50 E-value: 1.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI--KQQPSPDCLMLFQH 78
Cdd:PRK13540 1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSikKDLCTYQKQLCFVG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 79 HN--LLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:PRK13540 81 HRsgINPYLTLRENCLYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD 159
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-155 |
1.47e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 57.44 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIK-----Qqpspdclmlf 76
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGETVKlayvdQ---------- 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 77 QHHNLLPWKTI-------NDNIRIGfqqkisDEEINA-------------QLKLVDlegrgkhfpeQLSGGMKQRVALCR 136
Cdd:PRK11819 395 SRDALDPNKTVweeisggLDIIKVG------NREIPSrayvgrfnfkggdQQKKVG----------VLSGGERNRLHLAK 458
|
170
....*....|....*....
gi 2756312332 137 AHVHKPNVILMDEPLGALD 155
Cdd:PRK11819 459 TLKQGGNVLLLDEPTNDLD 477
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
33-183 |
2.71e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 56.67 E-value: 2.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 33 IGKSGCGKSTLLNIIGGFIHPSSGrviidnEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISD----EEINAQL 108
Cdd:PRK11819 39 LGLNGAGKSTLLRIMAGVDKEFEG------EARPAPGIKVGYLPQEPQLDPEKTVRENVEEGVAEVKAAldrfNEIYAAY 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 109 --------KLVDLEGR----------------------------GKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK11819 113 aepdadfdALAAEQGElqeiidaadawdldsqleiamdalrcppWDAKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTN 192
|
170 180 190
....*....|....*....|....*....|.
gi 2756312332 153 ALDAFTRYKLRDQLvqlkHKTESTIILVAHD 183
Cdd:PRK11819 193 HLDAESVAWLEQFL----HDYPGTVVAVTHD 219
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
16-200 |
2.79e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 57.26 E-value: 2.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIID---------NEIKQQPS--PDCLMLFQ---HHNL 81
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDglniakiglHDLRFKITiiPQDPVLFSgslRMNL 1380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPwktindnirigFQQkISDEEINAQLKLVDLEGRGKHFP-----------EQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:TIGR00957 1381 DP-----------FSQ-YSDEEVWWALELAHLKTFVSALPdkldhecaeggENLSVGQRQLVCLARALLRKTKILVLDEA 1448
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 151 LGALDAFTryklrDQLVQLKHKTE---STIILVAHDIDeAIYLSDRIVLLGEG 200
Cdd:TIGR00957 1449 TAAVDLET-----DNLIQSTIRTQfedCTVLTIAHRLN-TIMDYTRVIVLDKG 1495
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
12-208 |
3.86e-09 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 56.84 E-value: 3.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHpSSGRVIID----NEIKQQP-------SPDCLMLFQ--- 77
Cdd:TIGR01271 1230 AGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDgvswNSVTLQTwrkafgvIPQKVFIFSgtf 1308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 HHNLLPWktindnirigfqQKISDEEINAQLKLVDLEGRGKHFPEQL-----------SGGMKQRVALCRAHVHKPNVIL 146
Cdd:TIGR01271 1309 RKNLDPY------------EQWSDEEIWKVAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLARSILSKAKILL 1376
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 147 MDEPLGALDAFTRYKLRDqlvQLKHK-TESTIILVAHDIdEAIyLSDRIVLLGEGCNiISQYE 208
Cdd:TIGR01271 1377 LDEPSAHLDPVTLQIIRK---TLKQSfSNCTVILSEHRV-EAL-LECQQFLVIEGSS-VKQYD 1433
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
14-200 |
4.40e-09 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 56.19 E-value: 4.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCL----MLF-----QHHNLLPW 84
Cdd:COG3845 271 VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrrlgVAYipedrLGRGLVPD 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGFQQK--------ISDEEINAQ-LKLV---DLEGRGKHFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:COG3845 351 MSVAENLILGRYRRppfsrggfLDRKAIRAFaEELIeefDVRTPGPDTPaRSLSGGNQQKVILARELSRDPKLLIAAQPT 430
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 152 GALDAFTRYKLRDQLVQLKHKtESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:COG3845 431 RGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMYEG 478
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
11-196 |
4.46e-09 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 56.29 E-value: 4.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRViidneikqqpspdclMLFQhhnllpwKTIN-D 89
Cdd:NF033858 276 FGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEA---------------WLFG-------QPVDaG 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 90 NI----RIGF-------------QQ---------KISDEEINAQLKLV----DLEGRGKHFPEQLSGGMKQRVALCRAHV 139
Cdd:NF033858 334 DIatrrRVGYmsqafslygeltvRQnlelharlfHLPAAEIAARVAEMlerfDLADVADALPDSLPLGIRQRLSLAVAVI 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 140 HKPNVILMDEPL-----GALDAFTRYklrdqLVQLKHKTESTIILVAHDIDEAIyLSDRIVL 196
Cdd:NF033858 414 HKPELLILDEPTsgvdpVARDMFWRL-----LIELSREDGVTIFISTHFMNEAE-RCDRISL 469
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
14-200 |
5.18e-09 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 55.87 E-value: 5.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKS-TLLNIIGGFIHPS----SGRVIIDNEIKQQPSPDCL---------MLFQHH 79
Cdd:PRK15134 22 RTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLHASEQTLrgvrgnkiaMIFQEP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 --NLLPWKTIND------NIRIGFQQKISDEEINAQLKLVDLE---GRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMD 148
Cdd:PRK15134 102 mvSLNPLHTLEKqlyevlSLHRGMRREAARGEILNCLDRVGIRqaaKRLTDYPHQLSGGERQRVMIAMALLTRPELLIAD 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 149 EPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK15134 182 EPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNG 233
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
2-203 |
1.02e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 53.10 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHfgshkVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGgfihpssgrviidNEIKQQPSPDCLMLFQHHNL 81
Cdd:cd03238 1 LTVSGANVH-----NLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGL-------------YASGKARLISFLPKFSRNKL 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 lpwktindnIRIGfqqkisdeeinaQLKLVDLEGRGKHFPEQ----LSGGMKQRVALCR---AHVHkPNVILMDEPLGAL 154
Cdd:cd03238 63 ---------IFID------------QLQFLIDVGLGYLTLGQklstLSGGELQRVKLASelfSEPP-GTLFILDEPSTGL 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 155 DAFTRYKLRDQ---LVQLKHktesTIILVAHDiDEAIYLSDRIVLLGEGCNI 203
Cdd:cd03238 121 HQQDINQLLEVikgLIDLGN----TVILIEHN-LDVLSSADWIIDFGPGSGK 167
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
14-186 |
1.35e-08 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 54.90 E-value: 1.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 14 HKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRViidnEIKQQPSpdclMLFQHHNLLPWKTINDNIRI 93
Cdd:PRK13545 37 HYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV----DIKGSAA----LIAISSGLNGQLTGIENIEL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 94 -GFQQKISDEEINAQL-KLVDLEGRGK--HFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQ 168
Cdd:PRK13545 109 kGLMMGLTKEKIKEIIpEIIEFADIGKfiYQPvKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNE 188
|
170
....*....|....*...
gi 2756312332 169 LKHKTEsTIILVAHDIDE 186
Cdd:PRK13545 189 FKEQGK-TIFFISHSLSQ 205
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
15-200 |
1.42e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 54.74 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCL-----MLFQHHNLLPWKTIN 88
Cdd:PRK10982 12 KALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGkEIDFKSSKEALengisMVHQELNLVLQRSVM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGF---------QQKISDEEINAQLKL-VDLEGRGKhfPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFT 158
Cdd:PRK10982 92 DNMWLGRyptkgmfvdQDKMYRDTKAIFDELdIDIDPRAK--VATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKE 169
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2756312332 159 RYKLRDQLVQLKHKTeSTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10982 170 VNHLFTIIRKLKERG-CGIVYISHKMEEIFQLCDEITILRDG 210
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
24-155 |
1.55e-08 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 53.31 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 24 ISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHH--NLLPWKTINDNIRI--GFQQKI 99
Cdd:PRK13543 34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMAYLGHlpGLKADLSTLENLHFlcGLHGRR 113
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 100 SDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:PRK13543 114 AKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-220 |
1.62e-08 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 54.29 E-value: 1.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPD------CLM 74
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAkahqlgIYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLklvdLEGRGKHFPEQLSGGM-----KQRVALCRAHVHKPNVILMDE 149
Cdd:PRK15439 91 VPQEPLLFPNLSVKENILFGLPKRQASMQKMKQL----LAALGCQLDLDSSAGSlevadRQIVEILRGLMRDSRILILDE 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTEStIILVAHDIDEAIYLSDRIVLLGEGCNIIS----QYE----ITASHPRSRNDS 220
Cdd:PRK15439 167 PTASLTPAETERLFSRIRELLAQGVG-IVFISHKLPEIRQLADRISVMRDGTIALSgktaDLStddiIQAITPAAREKS 244
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
2-200 |
2.32e-08 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 53.95 E-value: 2.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGrviiDNEIKQQPSPDC--------L 73
Cdd:PRK10789 316 VNIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEG----DIRFHDIPLTKLqldswrsrL 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQHHNLLPWKTINDNIRIGfQQKISDEEINAQLKLVDLEGRGKHFPE-----------QLSGGMKQRVALCRAHVHKP 142
Cdd:PRK10789 392 AVVSQTPFLFSDTVANNIALG-RPDATQQEIEHVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIARALLLNA 470
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2756312332 143 NVILMDEPLGALDAFTRYKLRDQLVQLKHKteSTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:PRK10789 471 EILILDDALSAVDGRTEHQILHNLRQWGEG--RTVIISAHRL-SALTEASEILVMQHG 525
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
1-206 |
2.34e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 53.87 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGR--------VIIDNEIKQQPSPDc 72
Cdd:PRK10938 3 SLQISQGTFRLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGErqsqfshiTRLSFEQLQKLVSD- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 73 lmLFQHHN---LLPW-----KTINDNIRIGFQQKISDEEINAQLKLVDLEGRgkHFpEQLSGGMKQRVALCRAHVHKPNV 144
Cdd:PRK10938 82 --EWQRNNtdmLSPGeddtgRTTAEIIQDEVKDPARCEQLAQQFGITALLDR--RF-KYLSTGETRKTLLCQALMSEPDL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 145 ILMDEPLGALDAFTRYKLRDQLVQLkHKTESTIILVAHDIDEAIYLSDRIVLLGEgCNIISQ 206
Cdd:PRK10938 157 LILDEPFDGLDVASRQQLAELLASL-HQSGITLVLVLNRFDEIPDFVQFAGVLAD-CTLAET 216
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
16-200 |
3.68e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 53.59 E-value: 3.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 16 VIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE----------------IKQQPspdclMLFQ-- 77
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCdiskfglmdlrkvlgiIPQAP-----VLFSgt 1328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 78 -HHNLLPWKTINDnirigfqQKISDEEINAQLKLV------DLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEP 150
Cdd:PLN03130 1329 vRFNLDPFNEHND-------ADLWESLERAHLKDVirrnslGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEA 1401
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 151 LGALDAFTryklrDQLVQLKHKTE---STIILVAHDIDEAIYlSDRIVLLGEG 200
Cdd:PLN03130 1402 TAAVDVRT-----DALIQKTIREEfksCTMLIIAHRLNTIID-CDRILVLDAG 1448
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
19-199 |
5.56e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.86 E-value: 5.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLD-----ISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRViiDNEIK-----QQPSPDCLMlfqhhnllpwkTIN 88
Cdd:COG1245 353 GFSLEveggeIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV--DEDLKisykpQYISPDYDG-----------TVE 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 DNIRIGFQQKISD----EEINAQLKLvdlegrgKHFPEQ----LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY 160
Cdd:COG1245 420 EFLRSANTDDFGSsyykTEIIKPLGL-------EKLLDKnvkdLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRL 492
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2756312332 161 KLRDQLVQLKHKTESTIILVAHDI---DeaiYLSDRI-VLLGE 199
Cdd:COG1245 493 AVAKAIRRFAENRGKTAMVVDHDIyliD---YISDRLmVFEGE 532
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
11-231 |
6.09e-08 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 52.62 E-value: 6.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfIHPS---SGRVIIDNE------IKQQPSPDCLMLFQHHNL 81
Cdd:PRK13549 15 FGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPHgtyEGEIIFEGEelqasnIRDTERAGIAIIHQELAL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNI----------RIGFQQKISD-EEINAQLKL-VDLEGRGKHfpeqLSGGMKQRVALCRAHVHKPNVILMDE 149
Cdd:PRK13549 94 VKELSVLENIflgneitpggIMDYDAMYLRaQKLLAQLKLdINPATPVGN----LGLGQQQLVEIAKALNKQARLLILDE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTeSTIILVAHDIDEAIYLSDRIVLLGEGC-------------NIISQY---EITASH 213
Cdd:PRK13549 170 PTASLTESETAVLLDIIRDLKAHG-IACIYISHKLNEVKAISDTICVIRDGRhigtrpaagmtedDIITMMvgrELTALY 248
|
250
....*....|....*...
gi 2756312332 214 PRSRNDshllkIRNEIME 231
Cdd:PRK13549 249 PREPHT-----IGEVILE 261
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
7-200 |
7.06e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 53.06 E-value: 7.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 7 LQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN---------EIKQQPS--PDCLML 75
Cdd:PLN03232 1242 LRYRPGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDcdvakfgltDLRRVLSiiPQSPVL 1321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 76 FQ---HHNLLPWKTINDN------IRIGFQQKISDEE--INAQLklvdLEGrgkhfPEQLSGGMKQRVALCRAHVHKPNV 144
Cdd:PLN03232 1322 FSgtvRFNIDPFSEHNDAdlwealERAHIKDVIDRNPfgLDAEV----SEG-----GENFSVGQRQLLSLARALLRRSKI 1392
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2756312332 145 ILMDEPLGALDAFTryklrDQLVQLKHKTE---STIILVAHDIDeAIYLSDRIVLLGEG 200
Cdd:PLN03232 1393 LVLDEATASVDVRT-----DSLIQRTIREEfksCTMLVIAHRLN-TIIDCDKILVLSSG 1445
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
15-200 |
8.43e-08 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 52.13 E-value: 8.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLN-IIGGFIHPSSGRVIIDNeiKQQPSPDCLMLFQH-----------HNLL 82
Cdd:TIGR02633 274 KRVDDVSFSLRRGEILGVAGLVGAGRTELVQaLFGAYPGKFEGNVFING--KPVDIRNPAQAIRAgiamvpedrkrHGIV 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 83 PWKTINDNIRIGFQQKIS-----DEE-----INAQLKLVDLEGRGKHFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:TIGR02633 352 PILGVGKNITLSVLKSFCfkmriDAAaelqiIGSAIQRLKVKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPT 431
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 152 GALDAFTR---YKLRDQLVQlkhkTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR02633 432 RGVDVGAKyeiYKLINQLAQ----EGVAIIVVSSELAEVLGLSDRVLVIGEG 479
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
12-197 |
8.54e-08 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 52.11 E-value: 8.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 12 GSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfIHPSSGRVIIDNeikqqpspdclMLFQHHNLLPW------K 85
Cdd:PRK15093 18 GWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICG-VTKDNWRVTADR-----------MRFDDIDLLRLsprerrK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINDNIRIGFQQKIS----DEEINAQL-------------------------KLVDLEGRGKH------FPEQLSGGMKQ 130
Cdd:PRK15093 86 LVGHNVSMIFQEPQScldpSERVGRQLmqnipgwtykgrwwqrfgwrkrraiELLHRVGIKDHkdamrsFPYELTEGECQ 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 131 RVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLL 197
Cdd:PRK15093 166 KVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVL 232
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
19-200 |
9.75e-08 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 51.98 E-value: 9.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSPDCLML--------FQHHNL-----LPW 84
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGkEINALSTAQRLARglvylpedRQSSGLyldapLAW 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 K----TINDNiriGFQQKISDEE---------INAQLKLVDLEGRGkhfpeqLSGGMKQRVALCRAHVHKPNVILMDEPL 151
Cdd:PRK15439 361 NvcalTHNRR---GFWIKPARENavleryrraLNIKFNHAEQAART------LSGGNQQKVLIAKCLEASPQLLIVDEPT 431
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 152 GALDAFTRYKLRdQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK15439 432 RGVDVSARNDIY-QLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQG 479
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
19-183 |
1.02e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 52.17 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIidneikQQPSPDCLMLFQHHnlLPWKTINDNIRIGFQQ- 97
Cdd:PLN03073 527 NLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVF------RSAKVRMAVFSQHH--VDGLDLSSNPLLYMMRc 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 98 --KISDEEINAQLKLVDLEGRGKHFPE-QLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLkhktE 174
Cdd:PLN03073 599 fpGVPEQKLRAHLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGLVLF----Q 674
|
....*....
gi 2756312332 175 STIILVAHD 183
Cdd:PLN03073 675 GGVLMVSHD 683
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
15-200 |
4.20e-07 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 50.17 E-value: 4.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSP-DCL---MLFQHHN-----LLPWK 85
Cdd:PRK09700 277 KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPlDAVkkgMAYITESrrdngFFPNF 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 86 TINDNIRIGFQQKI------------SDEEINA--QLKLVDLEGrgkHFPEQ----LSGGMKQRVALCRAHVHKPNVILM 147
Cdd:PRK09700 357 SIAQNMAISRSLKDggykgamglfheVDEQRTAenQRELLALKC---HSVNQniteLSGGNQQKVLISKWLCCCPEVIIF 433
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2756312332 148 DEPLGALDAFTR---YKLRDQLVQlkhkTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK09700 434 DEPTRGIDVGAKaeiYKVMRQLAD----DGKVILMVSSELPEIITVCDRIAVFCEG 485
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
2-200 |
4.73e-07 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 49.52 E-value: 4.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSH--KVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDN-EIKQQPSpdclmlfqh 78
Cdd:cd03288 20 IKIHDLCVRYENNlkPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGiDISKLPL--------- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 79 HNLLPWKTI--------NDNIRIGF--QQKISDEEINAQLKLVDLEGRGKHFP-----------EQLSGGMKQRVALCRA 137
Cdd:cd03288 91 HTLRSRLSIilqdpilfSGSIRFNLdpECKCTDDRLWEALEIAQLKNMVKSLPggldavvteggENFSVGQRQLFCLARA 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2756312332 138 HVHKPNVILMDEPLGALDAFTRYKLrdQLVQLKHKTESTIILVAHDIdEAIYLSDRIVLLGEG 200
Cdd:cd03288 171 FVRKSSILIMDEATASIDMATENIL--QKVVMTAFADRTVVTIAHRV-STILDADLVLVLSRG 230
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
15-200 |
5.28e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 49.93 E-value: 5.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 15 KVIHNFNLDISKGEIVTFIGKSGCGKSTLLN-IIGGFIHPSSGRVIIDN-EIKQQPSPDCL-----MLFQ---HHNLLPW 84
Cdd:PRK13549 276 KRVDDVSFSLRRGEILGIAGLVGAGRTELVQcLFGAYPGRWEGEIFIDGkPVKIRNPQQAIaqgiaMVPEdrkRDGIVPV 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIRIGFQQKISD-EEINAQLKLVDLEGRGKHF------PEQ----LSGGMKQRVALCRAHVHKPNVILMDEPLGA 153
Cdd:PRK13549 356 MGVGKNITLAALDRFTGgSRIDDAAELKTILESIQRLkvktasPELaiarLSGGNQQKAVLAKCLLLNPKILILDEPTRG 435
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 154 LDA---FTRYKLRDQLVQlkhkTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK13549 436 IDVgakYEIYKLINQLVQ----QGVAIIVISSELPEVLGLSDRVLVMHEG 481
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
2-200 |
1.06e-06 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 48.96 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 2 IKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCG--KSTLLNIIGGfihPSSGRviidneikqqpSPDCLMLFQHH 79
Cdd:NF000106 14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGR-----------RPWRF*TWCAN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 80 NLLPWKTINDN--IRIGFQQKISDEE----INAQLKLV--DLEGRGKHFPEQLS-------------GGMKQRVALCRAH 138
Cdd:NF000106 80 RRALRRTIG*HrpVR*GRRESFSGREnlymIGR*LDLSrkDARARADELLERFSlteaagraaakysGGMRRRLDLAASM 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKhKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:NF000106 160 IGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV-RDGATVLLTTQYMEEAEQLAHELTVIDRG 220
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-200 |
2.20e-06 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 48.08 E-value: 2.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEI------KQQPSPDCLM 74
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEvtfngpKSSQEAGIGI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 LFQHHNLLPWKTINDNIRIG---------FQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVI 145
Cdd:PRK10762 84 IHQELNLIPQLTIAENIFLGrefvnrfgrIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 146 LMDEPLGAL-DAFTR------YKLRDQlvqlkhktESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10762 164 IMDEPTDALtDTETEslfrviRELKSQ--------GRGIVYISHRLKEIFEICDDVTVFRDG 217
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
17-184 |
4.06e-06 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 46.73 E-value: 4.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 17 IHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKqqpspdclMLFQHHNLLPWKTINDNIR---- 92
Cdd:PRK13546 40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVS--------VIAISAGLSGQLTGIENIEfkml 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 93 -IGFQQKisdeEINAQL-KLVDLEGRGK--HFP-EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLV 167
Cdd:PRK13546 112 cMGFKRK----EIKAMTpKIIEFSELGEfiYQPvKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIY 187
|
170
....*....|....*..
gi 2756312332 168 QLKHKTEsTIILVAHDI 184
Cdd:PRK13546 188 EFKEQNK-TIFFVSHNL 203
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
11-187 |
6.07e-06 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 46.55 E-value: 6.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfIHPS--------------SGRVIIDneIKQQ---PSPDCL 73
Cdd:PRK10938 270 YNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQgysndltlfgrrrgSGETIWD--IKKHigyVSSSLH 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 74 MLFQhhnllpwktINDNIR----------IGFQQKISD-EEINAQ--LKLVDLEGRGKHFPEQ-LSGGmKQRVAL-CRAH 138
Cdd:PRK10938 347 LDYR---------VSTSVRnvilsgffdsIGIYQAVSDrQQKLAQqwLDILGIDKRTADAPFHsLSWG-QQRLALiVRAL 416
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 139 VHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIILVAHDIDEA 187
Cdd:PRK10938 417 VKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDA 465
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
20-199 |
7.80e-06 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 46.32 E-value: 7.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDI-SKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRviIDNEikqqpsPDclmlfqhhnllpWKTINDNIR-IGFQ- 96
Cdd:COG1245 91 YGLPVpKKGKVTGILGPNGIGKSTALKILSGELKPNLGD--YDEE------PS------------WDEVLKRFRgTELQd 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 97 --QKISDEEINAQLK--LVD-------------LEG---RGK-----------HFPEQ----LSGGMKQRVALCRAHVHK 141
Cdd:COG1245 151 yfKKLANGEIKVAHKpqYVDlipkvfkgtvrelLEKvdeRGKldelaeklgleNILDRdiseLSGGELQRVAIAAALLRD 230
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 142 PNVILMDEPLGALDAFTRYKLRdQLVQLKHKTESTIILVAHDIdeAI--YLSDRIVLL-GE 199
Cdd:COG1245 231 ADFYFFDEPSSYLDIYQRLNVA-RLIRELAEEGKYVLVVEHDL--AIldYLADYVHILyGE 288
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
24-203 |
3.05e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 44.71 E-value: 3.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 24 ISKGEIVTFIGKSGCGKSTLLNIIGGFIHPS----SGRVIID----NEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGF 95
Cdd:TIGR00956 84 IKPGELTVVLGRPGSGCSTLLKTIASNTDGFhigvEGVITYDgitpEEIKKHYRGDVVYNAETDVHFPHLTVGETLDFAA 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 96 QQK--------ISDEEINAqlKLVDLEGR------------GKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALD 155
Cdd:TIGR00956 164 RCKtpqnrpdgVSREEYAK--HIADVYMAtyglshtrntkvGNDFVRGVSGGERKRVSIAEASLGGAKIQCWDNATRGLD 241
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2756312332 156 AFTRYKLRDQLVQLKHKTESTIILVAHDIDEAIY-LSDRIVLLGEGCNI 203
Cdd:TIGR00956 242 SATALEFIRALKTSANILDTTPLVAIYQCSQDAYeLFDKVIVLYEGYQI 290
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
124-206 |
4.75e-05 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 44.07 E-value: 4.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 124 LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKHKTESTIIL-VAHDIDEAIYLSDRIVLLGEGcN 202
Cdd:PLN03140 337 ISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMsLLQPAPETFDLFDDIILLSEG-Q 415
|
....
gi 2756312332 203 IISQ 206
Cdd:PLN03140 416 IVYQ 419
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
11-203 |
8.32e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 43.24 E-value: 8.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 11 FGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGfIHPS---SGRVIIDNE------IKQQPSPDCLMLFQHHNL 81
Cdd:NF040905 11 FPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG-VYPHgsyEGEILFDGEvcrfkdIRDSEALGIVIIHQELAL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 82 LPWKTINDNIRIGFQQK----ISDEEINAQ----LKLVDLEGRgkhfPEQLSG----GMKQRVALCRAHVHKPNVILMDE 149
Cdd:NF040905 90 IPYLSIAENIFLGNERAkrgvIDWNETNRRarelLAKVGLDES----PDTLVTdigvGKQQLVEIAKALSKDVKLLILDE 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 150 PLGALDAFTRYKLRDQLVQLKHKTESTIIlVAHDIDEAIYLSDRIVLLGEGCNI 203
Cdd:NF040905 166 PTAALNEEDSAALLDLLLELKAQGITSII-ISHKLNEIRRVADSITVLRDGRTI 218
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
19-200 |
9.75e-05 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 42.24 E-value: 9.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 19 NFNLDISKGEIVTFIGKSGCGKSTLlniigGF--IHPSSGR-------VIIDNEIKQQPSPDCLMLfqhHNLLP-----W 84
Cdd:cd03270 13 NVDVDIPRNKLVVITGVSGSGKSSL-----AFdtIYAEGQRryveslsAYARQFLGQMDKPDVDSI---EGLSPaiaidQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 85 KTINDNIR--IGFQQKISD--------EEINAQLK-LVDLeGRGKHFPEQ----LSGGMKQRVALCRaHVHK--PNVI-L 146
Cdd:cd03270 85 KTTSRNPRstVGTVTEIYDylrllfarVGIRERLGfLVDV-GLGYLTLSRsaptLSGGEAQRIRLAT-QIGSglTGVLyV 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2756312332 147 MDEPLGALDAFTRYKLRDQLVQLKHKTeSTIILVAHDiDEAIYLSDRIVLLGEG 200
Cdd:cd03270 163 LDEPSIGLHPRDNDRLIETLKRLRDLG-NTVLVVEHD-EDTIRAADHVIDIGPG 214
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-195 |
1.38e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 42.46 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 1 MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNE-----IKQQ-PSPDCLM 74
Cdd:PRK10636 1 MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNwqlawVNQEtPALPQPA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 75 L----------------FQHHNllpwkTINDNIRI----GFQQKISDEEINAQLKLVdLEGRGkhFP-EQL-------SG 126
Cdd:PRK10636 81 LeyvidgdreyrqleaqLHDAN-----ERNDGHAIatihGKLDAIDAWTIRSRAASL-LHGLG--FSnEQLerpvsdfSG 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2756312332 127 GMKQRVALCRAHVHKPNVILMDEPLGALDAftryklrDQLVQLKHKTES---TIILVAHDIDEAIYLSDRIV 195
Cdd:PRK10636 153 GWRMRLNLAQALICRSDLLLLDEPTNHLDL-------DAVIWLEKWLKSyqgTLILISHDRDFLDPIVDKII 217
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
20-199 |
1.42e-04 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 42.49 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 20 FNLDI-SKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRViiDNEikqqPSPDCLM-------LFQHHNLLPWKTIN--- 88
Cdd:PRK13409 91 YGLPIpKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDY--EEE----PSWDEVLkrfrgteLQNYFKKLYNGEIKvvh 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 89 -----DNIRIGFQQKISD-----------EEINAQLKLVDLEGRGKhfpEQLSGGMKQRVALCRAHVHKPNVILMDEPLG 152
Cdd:PRK13409 165 kpqyvDLIPKVFKGKVREllkkvdergklDEVVERLGLENILDRDI---SELSGGELQRVAIAAALLRDADFYFFDEPTS 241
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2756312332 153 ALDAFTRYKLRDQLVQLkhKTESTIILVAHDIdeAI--YLSDRIVLL-GE 199
Cdd:PRK13409 242 YLDIRQRLNVARLIREL--AEGKYVLVVEHDL--AVldYLADNVHIAyGE 287
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
124-200 |
2.37e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 41.64 E-value: 2.37e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2756312332 124 LSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRdQLVQLKHKTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIY-QLIAELAKKDKGIIIISSEMPELLGITDRILVMSNG 467
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
122-182 |
6.50e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 40.61 E-value: 6.50e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2756312332 122 EQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVqlkhKTESTIILVAH 182
Cdd:PLN03073 343 KTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLL----KWPKTFIVVSH 399
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
24-200 |
1.42e-03 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 39.61 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 24 ISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDclmLFQHHNLLPWKTINDNIRIGFQ------- 96
Cdd:TIGR01257 1962 VRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISD---VHQNMGYCPQFDAIDDLLTGREhlylyar 2038
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 97 -QKISDEEI----NAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLRDQLVQLKh 171
Cdd:TIGR01257 2039 lRGVPAEEIekvaNWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSII- 2117
|
170 180
....*....|....*....|....*....
gi 2756312332 172 KTESTIILVAHDIDEAIYLSDRIVLLGEG 200
Cdd:TIGR01257 2118 REGRAVVLTSHSMEECEALCTRLAIMVKG 2146
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
124-203 |
1.55e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 39.43 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756312332 124 LSGGMKQRVALCR---AHVHKPNVILmDEPLGALDAFTRYKLRDQLVQLKHKTeSTIILVAHDiDEAIYLSDRIVLLGEG 200
Cdd:PRK00635 477 LSGGEQERTALAKhlgAELIGITYIL-DEPSIGLHPQDTHKLINVIKKLRDQG-NTVLLVEHD-EQMISLADRIIDIGPG 553
|
...
gi 2756312332 201 CNI 203
Cdd:PRK00635 554 AGI 556
|
|
| |
