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Conserved domains on  [gi|2675117012|gb|WVW00558|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Xenogryllus lamottei]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 9.67e-22

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 80.97  E-value: 9.67e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  4 MMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDFSMYFSMIYLVFSVCEGALGLGILVSMVR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 2675117012 84 CYGNDFFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 9.67e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 80.97  E-value: 9.67e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  4 MMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDFSMYFSMIYLVFSVCEGALGLGILVSMVR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 2675117012 84 CYGNDFFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 3.13e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 44.09  E-value: 3.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  5 MIVLLLMSMYFSGVWVFcSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDF--SMYFSMIYLVFSVCEGALGLGILVSMV 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGL-LLRRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 2675117012 83 RCYGNDFFQSFVVLRC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 9.67e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 80.97  E-value: 9.67e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  4 MMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDFSMYFSMIYLVFSVCEGALGLGILVSMVR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 2675117012 84 CYGNDFFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 6.04e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 56.39  E-value: 6.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  3 MMMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDFSMYFSMIYLVFSVCEGALGLGILVSMV 82
Cdd:MTH00149   2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                         90
                 ....*....|....*.
gi 2675117012 83 RCYGNDFFQSFVVLRC 98
Cdd:MTH00149  82 RLHGNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 3-98 8.98e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 48.43  E-value: 8.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  3 MMMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDFSMYFSMIYLVFSVCEGALGLGILVSMV 82
Cdd:MTH00188   2 FFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLI 81

                         90
                 ....*....|....*.
gi 2675117012 83 RCYGNDFFQSFVVLRC 98
Cdd:MTH00188  82 RSHGSDYVSSLNLIKC 97
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 25-98 1.27e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 48.04  E-value: 1.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012 25 RKHLLMVLLSLEYMVIftfSLFISwLNLYDF---SMYFS---MIYLVFSVCEGALGLGILVSMVRCYGNDFFQSFVVLRC 98
Cdd:MTH00126  23 RTHLLSALLCLEGMML---SLFIA-LSLWALqleSTSFSaapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 3-98 1.68e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 44.98  E-value: 1.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  3 MMMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDFSMYFS--MIYLVFSVCEGALGLGILVS 80
Cdd:MTH00067   1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVA 80

                         90
                 ....*....|....*...
gi 2675117012 81 MVRCYGNDFFQSFVVLRC 98
Cdd:MTH00067  81 TTRTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 3.13e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 44.09  E-value: 3.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  5 MIVLLLMSMYFSGVWVFcSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYDF--SMYFSMIYLVFSVCEGALGLGILVSMV 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGL-LLRRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 2675117012 83 RCYGNDFFQSFVVLRC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 3-98 7.47e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 43.30  E-value: 7.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  3 MMMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTF---SLFISWLNLYDFSMyFSMIYLVFSVCEGALGLGILV 79
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFimlSLWPITTQTPSFTP-MPIILLTFSACEAGTGLALLV 79

                         90
                 ....*....|....*....
gi 2675117012 80 SMVRCYGNDFFQSFVVLRC 98
Cdd:MTH00125  80 ATTRTHGSDHLKNLNLLQC 98
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 8.80e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 42.98  E-value: 8.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  3 MMMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISWLNLYD--FSMYFSMIYLVFSVCEGALGLGILVS 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGnfSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 2675117012 81 MVRCYGNDFFQSFVVLR 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 3-98 1.00e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 43.20  E-value: 1.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  3 MMMIVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVI-FTFSLFISWLNLYDFSMYFSMIYLVFSVCEGALGLGILVSM 81
Cdd:MTH00013   1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILsLALFIPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVLM 80

                         90
                 ....*....|....*..
gi 2675117012 82 VRCYGNDFFQSFVVLRC 98
Cdd:MTH00013  81 TRSYGNDMLKSLTSNKC 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 6-93 1.72e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 39.54  E-value: 1.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  6 IVLLLMSMYFSGVWVFCSKRKHLLMVLLSLEYMVIFTFSLFISW--LNLYDFSMYFSMIYLVFSVCEGALGLGILVSMVR 83
Cdd:MTH00181   1 MMFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFslLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNR 80

                         90
                 ....*....|
gi 2675117012 84 CYGNDFFQSF 93
Cdd:MTH00181  81 THGSDHLLKF 90
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 2-98 2.50e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 39.53  E-value: 2.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2675117012  2 YMMMIVLLLMSMYFSGVWVFcskRKHLLMVLLSLEYMVIFTFSLF-ISWLNLYDFSMY-FSMIYLVFSVCEGALGLGILV 79
Cdd:MTH00107   3 LIYMNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMAtLTILNTHFTLASmMPIILLVFAACEAAVGLALLV 79

                         90
                 ....*....|....*....
gi 2675117012 80 SMVRCYGNDFFQSFVVLRC 98
Cdd:MTH00107  80 MVSNTYGTDYVQNLNLLQC 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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