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Conserved domains on  [gi|2713923541|gb|WYX94301|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Nepsalus jezoensis]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-91 5.23e-23

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 84.05  E-value: 5.23e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  4 LNLLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2713923541 84 HGNDYFQS 91
Cdd:MTH00162  82 HGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-91 5.23e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 84.05  E-value: 5.23e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  4 LNLLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2713923541 84 HGNDYFQS 91
Cdd:MTH00162  82 HGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
6-95 9.66e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.94  E-value: 9.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSyVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNF--EFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:pfam00420  3 LLLSGLLFLIGLYG-LLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIYRT 81

                         90
                 ....*....|..
gi 2713923541 84 HGNDYFQSLNIL 95
Cdd:pfam00420 82 HGTDDVDSLNLL 93
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-91 5.23e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 84.05  E-value: 5.23e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  4 LNLLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2713923541 84 HGNDYFQS 91
Cdd:MTH00162  82 HGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 6-94 6.59e-15

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 63.84  E-value: 6.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFSMIFLTFSVCEGSLGLSILVSMVRTHG 85
Cdd:MTH00188   6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85


                 ....*....
gi 2713923541 86 NDYFQSLNI 94
Cdd:MTH00188  86 SDYVSSLNL 94
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 13-95 1.38e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 60.75  E-value: 1.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541 13 YLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFS--MIFLTFSVCEGSLGLSILVSMVRTHGNDYFQ 90
Cdd:MTH00126  12 FILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQ 91


                 ....*
gi 2713923541 91 SLNIL 95
Cdd:MTH00126  92 NLNLL 96
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 3-95 3.72e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 59.47  E-value: 3.72e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  3 ELNLLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFSM--IFLTFSVCEGSLGLSILVSM 80
Cdd:MTH00125   2 TPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVAT 81

                         90
                 ....*....|....*
gi 2713923541 81 VRTHGNDYFQSLNIL 95
Cdd:MTH00125  82 TRTHGSDHLKNLNLL 96
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 6-92 6.67e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 58.70  E-value: 6.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFSMIFLTFSVCEGSLGLSILVSMVRTHG 85
Cdd:MTH00149   6 LLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHG 85


                 ....*..
gi 2713923541 86 NDYFQSL 92
Cdd:MTH00149  86 NDYVSSL 92
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 12-95 8.16e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 53.45  E-value: 8.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541 12 MYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFFFS--MIFLTFSVCEGSLGLSILVSMVRTHGNDYF 89
Cdd:MTH00067  11 AFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVATTRTHGTDHL 90


                 ....*.
gi 2713923541 90 QSLNIL 95
Cdd:MTH00067  91 KNLNLL 96
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-95 1.80e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 49.93  E-value: 1.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  1 MVELNLLIVVLMYLCGCLSYvlkRKHLLSMLLSLEFIVLSLFFL--LIMSLMYFNFEFFFSMIFLTFSVCEGSLGLSILV 78
Cdd:MTH00107   3 LIYMNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLV 79

                         90
                 ....*....|....*..
gi 2713923541 79 SMVRTHGNDYFQSLNIL 95
Cdd:MTH00107  80 MVSNTYGTDYVQNLNLL 96
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-95 1.90e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 49.94  E-value: 1.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  7 LIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNF--EFFFSMIFLTFSVCEGSLGLSILVSMVRTH 84
Cdd:MTH00181   3 FVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRTH 82

                         90
                 ....*....|.
gi 2713923541 85 GNDYFQSLNIL 95
Cdd:MTH00181  83 GSDHLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
6-95 9.66e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.94  E-value: 9.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSyVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNF--EFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:pfam00420  3 LLLSGLLFLIGLYG-LLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIYRT 81

                         90
                 ....*....|..
gi 2713923541 84 HGNDYFQSLNIL 95
Cdd:pfam00420 82 HGTDDVDSLNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 6-96 1.25e-08

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 47.99  E-value: 1.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFNFEFF--FSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:MTH00043   5 LIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLLSRN 84

                         90
                 ....*....|...
gi 2713923541 84 HGNDYFQSLNILN 96
Cdd:MTH00043  85 HNSDLVASLNLLQ 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 6-92 3.99e-08

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 46.67  E-value: 3.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFN-FEFFFSMIFLTFSVCEGSLGLSILVSMVRTH 84
Cdd:MTH00013   5 LFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANqVNGMLAIVLLTFGACEASLGLSLLVLMTRSY 84


                 ....*...
gi 2713923541 85 GNDYFQSL 92
Cdd:MTH00013  85 GNDMLKSL 92
ND4L MTH00001
NADH dehydrogenase subunit 4L; Provisional
 6-95 8.27e-04

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177099  Cd Length: 99  Bit Score: 35.42  E-value: 8.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFN--FEFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:MTH00001   6 LILVVILFLLGIWGIILNRGHFIIMLVSIELVLLSTFFLFLINSIEIDllIEQIFTIMGLTIAAAESAIGLAIMVAYYRI 85

                         90
                 ....*....|..
gi 2713923541 84 HGNDYFQSLNIL 95
Cdd:MTH00001  86 RGTISLKSLNSL 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 6-95 5.95e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 33.08  E-value: 5.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2713923541  6 LLIVVLMYLCGCLSYVLKRKHLLSMLLSLEFIVLSLFFLLIMSLMYFN--FEFFFSMIFLTFSVCEGSLGLSILVSMVRT 83
Cdd:MTH00180   6 LTVGIILFILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDnlIGQIFTIMILTVAAAESAIGLAILVAYYRI 85

                         90
                 ....*....|..
gi 2713923541 84 HGNDYFQSLNIL 95
Cdd:MTH00180  86 RGTIAVKSLNLL 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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