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Conserved domains on  [gi|195433343|ref|XP_002064674|]
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RNA polymerase I-specific transcription initiation factor RRN3 [Drosophila willistoni]

Protein Classification

RNA polymerase I-specific transcription initiation factor RRN3 family protein( domain architecture ID 10526375)

RNA polymerase I-specific transcription initiation factor RRN3 family protein similar to human RRN3 that is required for efficient transcription initiation by RNA polymerase I, and for the formation of the competent preinitiation complex (PIC).

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 39-565 2.31e-163

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


:

Pssm-ID: 461623  Cd Length: 548  Bit Score: 478.64  E-value: 2.31e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343   39 KEKGLKESIRVALEEH---DYHLVQEFSYFLCEAD-----LSDEEVIQIMNDARKICHSLTSNFAGVVEALLSVNWRKRS 110
Cdd:pfam05327   4 SDKMYREFVRRALEEHekgDSEQYDELKEQFSPDPespdaPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  111 SEAIEAYTEFAIDIMVAHSTYIPIGISKFIVHWVPTEneSSEWQIHGCPSEIVRNDLETVHKILDRILTAVPMSFDVVID 190
Cdd:pfam05327  84 ESFVKAYIRFLGVLASAHPKYLSLVLSMLVSNFTPQP--ESSGRLPGYPPVTRREVYERVHEALKYILRLIPTAPSVLLP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  191 AISAKFPYFKKPSYVTAGYLYNILRLLEYKPVFEELVMQLVLQKLLILDV--------------NAPRDEIDVETDDEED 256
Cdd:pfam05327 162 ILSRKFPHKRDSKKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDVeiqveledldddedEELLEQLDEDDDDDDD 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  257 DDEDREPDKMDEDGIFQMDDIPTKSPSPLaktidHPIGQTLDICLAMLYKFLDTKCRlAPTTNEEQRWTANRFFKMLLFI 336
Cdd:pfam05327 242 DDSDDDSDSSDDGLDDDEEDDEVQRIKKI-----KELVEKLDAILDLLFEHLDSKFS-SGSPEELNEGEGVEVFNTLLSL 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  337 FDEVLLPSHNTCHVQFVIFQVCSLRPAYAEAFLSSLWLKVQNPNVSSIIRHAAVSYMASFMARSKFLPLSTIKFYLTELS 416
Cdd:pfam05327 316 FKSTILPTYRSRHTQFLLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLC 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  417 KWSLRYIDDTDEyNSQNGSLKANMVFFSVCQALFYLIAFRAKDLTAGTKELLFLQSL-------QLSRLAMCHLNPLRYC 489
Cdd:pfam05327 396 DWLNRYVDEREE-ECRGPDLKRHGVFYAVCQALLYIFCFRWRDLTDADDDEEGGDLEwlpgldeFLQRAIYSKLNPLKVC 474

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 195433343  490 LPPVATAFAGITRTHQLAYCHTVLERNARRKLAtvyGHDKAMPEETLETFFPFDPYLLKLSNKYIEPHYLVYKAHD 565
Cdd:pfam05327 475 SPNVVTEFARIAHHLQFAYCFSIIESNKREETA---GTATGQEFEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVA 547
 
Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 39-565 2.31e-163

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


Pssm-ID: 461623  Cd Length: 548  Bit Score: 478.64  E-value: 2.31e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343   39 KEKGLKESIRVALEEH---DYHLVQEFSYFLCEAD-----LSDEEVIQIMNDARKICHSLTSNFAGVVEALLSVNWRKRS 110
Cdd:pfam05327   4 SDKMYREFVRRALEEHekgDSEQYDELKEQFSPDPespdaPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  111 SEAIEAYTEFAIDIMVAHSTYIPIGISKFIVHWVPTEneSSEWQIHGCPSEIVRNDLETVHKILDRILTAVPMSFDVVID 190
Cdd:pfam05327  84 ESFVKAYIRFLGVLASAHPKYLSLVLSMLVSNFTPQP--ESSGRLPGYPPVTRREVYERVHEALKYILRLIPTAPSVLLP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  191 AISAKFPYFKKPSYVTAGYLYNILRLLEYKPVFEELVMQLVLQKLLILDV--------------NAPRDEIDVETDDEED 256
Cdd:pfam05327 162 ILSRKFPHKRDSKKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDVeiqveledldddedEELLEQLDEDDDDDDD 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  257 DDEDREPDKMDEDGIFQMDDIPTKSPSPLaktidHPIGQTLDICLAMLYKFLDTKCRlAPTTNEEQRWTANRFFKMLLFI 336
Cdd:pfam05327 242 DDSDDDSDSSDDGLDDDEEDDEVQRIKKI-----KELVEKLDAILDLLFEHLDSKFS-SGSPEELNEGEGVEVFNTLLSL 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  337 FDEVLLPSHNTCHVQFVIFQVCSLRPAYAEAFLSSLWLKVQNPNVSSIIRHAAVSYMASFMARSKFLPLSTIKFYLTELS 416
Cdd:pfam05327 316 FKSTILPTYRSRHTQFLLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLC 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  417 KWSLRYIDDTDEyNSQNGSLKANMVFFSVCQALFYLIAFRAKDLTAGTKELLFLQSL-------QLSRLAMCHLNPLRYC 489
Cdd:pfam05327 396 DWLNRYVDEREE-ECRGPDLKRHGVFYAVCQALLYIFCFRWRDLTDADDDEEGGDLEwlpgldeFLQRAIYSKLNPLKVC 474

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 195433343  490 LPPVATAFAGITRTHQLAYCHTVLERNARRKLAtvyGHDKAMPEETLETFFPFDPYLLKLSNKYIEPHYLVYKAHD 565
Cdd:pfam05327 475 SPNVVTEFARIAHHLQFAYCFSIIESNKREETA---GTATGQEFEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVA 547
 
Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 39-565 2.31e-163

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


Pssm-ID: 461623  Cd Length: 548  Bit Score: 478.64  E-value: 2.31e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343   39 KEKGLKESIRVALEEH---DYHLVQEFSYFLCEAD-----LSDEEVIQIMNDARKICHSLTSNFAGVVEALLSVNWRKRS 110
Cdd:pfam05327   4 SDKMYREFVRRALEEHekgDSEQYDELKEQFSPDPespdaPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  111 SEAIEAYTEFAIDIMVAHSTYIPIGISKFIVHWVPTEneSSEWQIHGCPSEIVRNDLETVHKILDRILTAVPMSFDVVID 190
Cdd:pfam05327  84 ESFVKAYIRFLGVLASAHPKYLSLVLSMLVSNFTPQP--ESSGRLPGYPPVTRREVYERVHEALKYILRLIPTAPSVLLP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  191 AISAKFPYFKKPSYVTAGYLYNILRLLEYKPVFEELVMQLVLQKLLILDV--------------NAPRDEIDVETDDEED 256
Cdd:pfam05327 162 ILSRKFPHKRDSKKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDVeiqveledldddedEELLEQLDEDDDDDDD 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  257 DDEDREPDKMDEDGIFQMDDIPTKSPSPLaktidHPIGQTLDICLAMLYKFLDTKCRlAPTTNEEQRWTANRFFKMLLFI 336
Cdd:pfam05327 242 DDSDDDSDSSDDGLDDDEEDDEVQRIKKI-----KELVEKLDAILDLLFEHLDSKFS-SGSPEELNEGEGVEVFNTLLSL 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  337 FDEVLLPSHNTCHVQFVIFQVCSLRPAYAEAFLSSLWLKVQNPNVSSIIRHAAVSYMASFMARSKFLPLSTIKFYLTELS 416
Cdd:pfam05327 316 FKSTILPTYRSRHTQFLLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLC 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195433343  417 KWSLRYIDDTDEyNSQNGSLKANMVFFSVCQALFYLIAFRAKDLTAGTKELLFLQSL-------QLSRLAMCHLNPLRYC 489
Cdd:pfam05327 396 DWLNRYVDEREE-ECRGPDLKRHGVFYAVCQALLYIFCFRWRDLTDADDDEEGGDLEwlpgldeFLQRAIYSKLNPLKVC 474

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 195433343  490 LPPVATAFAGITRTHQLAYCHTVLERNARRKLAtvyGHDKAMPEETLETFFPFDPYLLKLSNKYIEPHYLVYKAHD 565
Cdd:pfam05327 475 SPNVVTEFARIAHHLQFAYCFSIIESNKREETA---GTATGQEFEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVA 547
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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