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Conserved domains on  [gi|530399245|ref|XP_005253472|]
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coiled-coil domain-containing protein 91 isoform X5 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 103-378 1.15e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 103 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISfQDRYKELQEKHKQELEDMRKAGHEALSI 182
Cdd:COG1196  243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQDIARLEERRRELEERLEEL 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 183 IVDEYKALLQ-SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRL-LEMLDTEKELLKEKIKEALIQQSQEQKEILEK 260
Cdd:COG1196  322 EEELAELEEElEELEEELEELEEELEEAEEELEEAEAELAEAEEALLeAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 261 CLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAhAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETV 340
Cdd:COG1196  402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 530399245 341 KAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQ 378
Cdd:COG1196  481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 103-378 1.15e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 103 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISfQDRYKELQEKHKQELEDMRKAGHEALSI 182
Cdd:COG1196  243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQDIARLEERRRELEERLEEL 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 183 IVDEYKALLQ-SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRL-LEMLDTEKELLKEKIKEALIQQSQEQKEILEK 260
Cdd:COG1196  322 EEELAELEEElEELEEELEELEEELEEAEEELEEAEAELAEAEEALLeAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 261 CLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAhAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETV 340
Cdd:COG1196  402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 530399245 341 KAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQ 378
Cdd:COG1196  481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
PTZ00121 PTZ00121
MAEBL; Provisional
 105-398 2.59e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  105 QQKISSLEIKLKVSEEEK-QRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAgHEALSII 183
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-DEAKKKA 1453

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  184 VDEYKAllQSSVKQQVEAIEKQYISAIEKQAHKCEELlNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLE 263
Cdd:PTZ00121 1454 EEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEA-KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  264 EERQRNKEALVSAAKLEKEAVKDAV-LKVVEEERKNLEKAHAEERELWKTEHA----KDQEKVSQEIQKAIQEQRKISQE 338
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADELKKAEeLKKAEEKKKAEEAKKAEEDKNMALRKAeeakKAEEARIEEVMKLYEEEKKMKAE 1610

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  339 TVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQ 398
Cdd:PTZ00121 1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 119-411 6.52e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 6.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  119 EEEKQRIKQ-DVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGhealsiIVDEYKALLQSSVKQ 197
Cdd:pfam17380 347 ERELERIRQeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVK------ILEEERQRKIQQQKV 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  198 QVEAIEKQYISAIEKQAHKCEELLNAQHQRLlemldTEKELLKEKIKEALIQQSQEQKeilEKCLEEERQRNKEALVSaa 277
Cdd:pfam17380 421 EMEQIRAEQEEARQREVRRLEEERAREMERV-----RLEEQERQQQVERLRQQEEERK---RKKLELEKEKRDRKRAE-- 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  278 klekeavkdavlkvvEEERKNLEKAHAEERELWKTEHAKDQ--EKVSQEIQKAIQEQRkisqetvKAAIIEEQKRSEKAV 355
Cdd:pfam17380 491 ---------------EQRRKILEKELEERKQAMIEEERKRKllEKEMEERQKAIYEEE-------RRREAEEERRKQQEM 548

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530399245  356 EEAvKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSAliATEPVDIE 411
Cdd:pfam17380 549 EER-RRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEA--TTPITTIK 601
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 135-382 6.11e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 6.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   135 KHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEalsiivdeyKALLQSSVKQQVEAIEKQYISAIEKQA 214
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE---------LSRQISALRKDLARLEAEVEQLEERIA 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   215 HKCEELLNAQHQRllEMLDTEKELLKEKIKEALIQQSQEQKEILEkcLEEERQRNKEALvSAAKLEKEAVKDAVLKVVEE 294
Cdd:TIGR02168  751 QLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELEAQIEQ--LKEELKALREAL-DELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   295 ERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKaVEEAVKRTRDELIEYIKEQK 374
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-LEEALALLRSELEELSEELR 904


                   ....*...
gi 530399245   375 RLDQVIRQ 382
Cdd:TIGR02168  905 ELESKRSE 912
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 103-378 1.15e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 103 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISfQDRYKELQEKHKQELEDMRKAGHEALSI 182
Cdd:COG1196  243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQDIARLEERRRELEERLEEL 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 183 IVDEYKALLQ-SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRL-LEMLDTEKELLKEKIKEALIQQSQEQKEILEK 260
Cdd:COG1196  322 EEELAELEEElEELEEELEELEEELEEAEEELEEAEAELAEAEEALLeAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 261 CLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAhAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETV 340
Cdd:COG1196  402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 530399245 341 KAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQ 378
Cdd:COG1196  481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 102-358 1.36e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.36e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 102 IQLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGfLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALS 181
Cdd:COG1196  298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 182 IIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAhkceellnAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEkc 261
Cdd:COG1196  377 AEEELEELAEELLEALRAAAELAAQLEELEEAE--------EALLERLERLEEELEELEEALAELEEEEEEEEEALEE-- 446

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 262 LEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVK 341
Cdd:COG1196  447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                        250
                 ....*....|....*..
gi 530399245 342 AAIIEEQKRSEKAVEEA 358
Cdd:COG1196  527 AVLIGVEAAYEAALEAA 543
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 144-409 1.18e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 144 LKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNA 223
Cdd:COG1196  234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 224 QHQRLLEMLDTEKELLKEkikealIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDavlkvvEEERKNLEKAH 303
Cdd:COG1196  314 LEERLEELEEELAELEEE------LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA------EAELAEAEEEL 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 304 AEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQR 383
Cdd:COG1196  382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                        250       260
                 ....*....|....*....|....*.
gi 530399245 384 SLSSLELFLSCAQKQLSALIATEPVD 409
Cdd:COG1196  462 LELLAELLEEAALLEAALAELLEELA 487
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 114-382 1.35e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 1.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 114 KLKVSEEEKQRIKQDVESLMEKHNVLEKGfLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVD-EYKALLQ 192
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAE-LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiARLEERR 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 193 SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQrlLEMLDTEKELLKEKIKEALIQQSQEQKEILEKclEEERQRNKEA 272
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEE--LEEAEEELEEAEAELAEAEEALLEAEAELAEA--EEELEELAEE 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 273 LVSAAKLEKEAVKD-AVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRS 351
Cdd:COG1196  388 LLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                        250       260       270
                 ....*....|....*....|....*....|.
gi 530399245 352 EKAVEEAVKRTRDELIEYIKEQKRLDQVIRQ 382
Cdd:COG1196  468 LLEEAALLEAALAELLEELAEAAARLLLLLE 498
PTZ00121 PTZ00121
MAEBL; Provisional
 105-398 2.59e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  105 QQKISSLEIKLKVSEEEK-QRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAgHEALSII 183
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-DEAKKKA 1453

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  184 VDEYKAllQSSVKQQVEAIEKQYISAIEKQAHKCEELlNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLE 263
Cdd:PTZ00121 1454 EEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEA-KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  264 EERQRNKEALVSAAKLEKEAVKDAV-LKVVEEERKNLEKAHAEERELWKTEHA----KDQEKVSQEIQKAIQEQRKISQE 338
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADELKKAEeLKKAEEKKKAEEAKKAEEDKNMALRKAeeakKAEEARIEEVMKLYEEEKKMKAE 1610

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  339 TVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQ 398
Cdd:PTZ00121 1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 119-411 6.52e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 6.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  119 EEEKQRIKQ-DVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGhealsiIVDEYKALLQSSVKQ 197
Cdd:pfam17380 347 ERELERIRQeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVK------ILEEERQRKIQQQKV 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  198 QVEAIEKQYISAIEKQAHKCEELLNAQHQRLlemldTEKELLKEKIKEALIQQSQEQKeilEKCLEEERQRNKEALVSaa 277
Cdd:pfam17380 421 EMEQIRAEQEEARQREVRRLEEERAREMERV-----RLEEQERQQQVERLRQQEEERK---RKKLELEKEKRDRKRAE-- 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  278 klekeavkdavlkvvEEERKNLEKAHAEERELWKTEHAKDQ--EKVSQEIQKAIQEQRkisqetvKAAIIEEQKRSEKAV 355
Cdd:pfam17380 491 ---------------EQRRKILEKELEERKQAMIEEERKRKllEKEMEERQKAIYEEE-------RRREAEEERRKQQEM 548

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530399245  356 EEAvKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSAliATEPVDIE 411
Cdd:pfam17380 549 EER-RRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEA--TTPITTIK 601
PTZ00121 PTZ00121
MAEBL; Provisional
 116-374 1.24e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  116 KVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQEL---EDMRKAgHEALSIIVDEYKALLQ 192
Cdd:PTZ00121 1504 KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELkkaEEKKKA-EEAKKAEEDKNMALRK 1582

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  193 SSVKQQVEA--IEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNK 270
Cdd:PTZ00121 1583 AEEAKKAEEarIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  271 EALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQE----KVSQEIQKAiQEQRKISQETVKAAIIE 346
Cdd:PTZ00121 1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEaeekKKAEELKKA-EEENKIKAEEAKKEAEE 1741

                         250       260
                  ....*....|....*....|....*...
gi 530399245  347 EQKRSEKAVEEAVKRTRDELIEYIKEQK 374
Cdd:PTZ00121 1742 DKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
PTZ00121 PTZ00121
MAEBL; Provisional
 112-377 1.33e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  112 EIKLKVSEEEKQRIKQDVESLmEKHNVLEKGFLKEKEQEAISFQDRyKELQEKHKQELEDMRKAGHEALSIIVDEYKALL 191
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADEL-KKAEELKKAEEKKKAEEAKKAEED-KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  192 QSSVKQQVEA-IEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQ--KEILEKCLEEERQR 268
Cdd:PTZ00121 1609 AEEAKKAEEAkIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkKKAEEAKKAEEDEK 1688

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  269 NKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQE----KVSQEIQKAIQEQRKISQETVKAAI 344
Cdd:PTZ00121 1689 KAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAeedkKKAEEAKKDEEEKKKIAHLKKEEEK 1768

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 530399245  345 IEEQKRSEK--AVEEAVKRtRDELIEYIKEQKRLD 377
Cdd:PTZ00121 1769 KAEEIRKEKeaVIEEELDE-EDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 135-382 6.11e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 6.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   135 KHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEalsiivdeyKALLQSSVKQQVEAIEKQYISAIEKQA 214
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE---------LSRQISALRKDLARLEAEVEQLEERIA 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   215 HKCEELLNAQHQRllEMLDTEKELLKEKIKEALIQQSQEQKEILEkcLEEERQRNKEALvSAAKLEKEAVKDAVLKVVEE 294
Cdd:TIGR02168  751 QLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELEAQIEQ--LKEELKALREAL-DELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   295 ERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKaVEEAVKRTRDELIEYIKEQK 374
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-LEEALALLRSELEELSEELR 904


                   ....*...
gi 530399245   375 RLDQVIRQ 382
Cdd:TIGR02168  905 ELESKRSE 912
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 160-382 8.30e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 8.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 160 ELQEKHKQELEDMRKAGHEALSIIVDEYKAllQSSVKQQVEAIEKQyISAIEKQAHKCEELLNAQHQRLlemldTEKELL 239
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKE--EKALLKQLAALERR-IAALARRIRALEQELAALEAEL-----AELEKE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 240 KEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEER-ELWKTEHAKDQ 318
Cdd:COG4942   92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLaELAALRAELEA 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530399245 319 EKVSQEIQKAIQEQRKISQETVKAaiieEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQ 382
Cdd:COG4942  172 ERAELEALLAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 103-377 2.72e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 2.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   103 QLQQKISSLEIKLKVSEEEKQRIKQDVESL------MEKHNVLEKGFLKEKEQEAISFQDRYkELQEKHKQELEDMRKAG 176
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLrkeleeLSRQISALRKDLARLEAEVEQLEERI-AQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   177 HEALSIIVDEYKALLQ--SSVKQQVEAIEKQyISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKI-KEALIQQSQE 253
Cdd:TIGR02168  767 EERLEEAEEELAEAEAeiEELEAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAaTERRLEDLEE 845

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   254 QKEILEKCLEEERQRNKEALVSAAKLEKEavkdavLKVVEEERKNLEKAHAEERElwktehakDQEKVSQEIQKAIQEQR 333
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESE------LEALLNERASLEEALALLRS--------ELEELSEELRELESKRS 911

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 530399245   334 KISQETVKAaiiEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLD 377
Cdd:TIGR02168  912 ELRRELEEL---REKLAQLELRLEGLEVRIDNLQERLSEEYSLT 952
PTZ00121 PTZ00121
MAEBL; Provisional
 114-375 2.93e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  114 KLKVSEEEKQRIKQDVESLMEKHNVLEKgflkekEQEAISFQDRYKELQEKHKQELEDMRKAghEALSIIVDEYKALLQS 193
Cdd:PTZ00121 1358 EAEAAEEKAEAAEKKKEEAKKKADAAKK------KAEEKKKADEAKKKAEEDKKKADELKKA--AAAKKKADEAKKKAEE 1429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  194 SVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEAL 273
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  274 VSAAKLEK--EAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRS 351
Cdd:PTZ00121 1510 KKADEAKKaeEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589

                         250       260
                  ....*....|....*....|....
gi 530399245  352 EKAVEEAVKRTRDELIEYIKEQKR 375
Cdd:PTZ00121 1590 EEARIEEVMKLYEEEKKMKAEEAK 1613
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
115-301 4.98e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  115 LKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMR--KAGHEALSIIVDEYKALLQ 192
Cdd:COG4913   254 LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELErlEARLDALREELDELEAQIR 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  193 SSVKQQVEAIEKQyISAIEKQAHKCEELLNAQHQRL----LEMLDTEKELlkekikEALIQQSQEQKEILEKCLEEERQR 268
Cdd:COG4913   334 GNGGDRLEQLERE-IERLERELEERERRRARLEALLaalgLPLPASAEEF------AALRAEAAALLEALEEELEALEEA 406

                         170       180       190
                  ....*....|....*....|....*....|...
gi 530399245  269 NKEALVSAAKLEKEavkdavLKVVEEERKNLEK 301
Cdd:COG4913   407 LAEAEAALRDLRRE------LRELEAEIASLER 433
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 103-374 5.34e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 5.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   103 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGF-------------LKEKEQEAISFQDRYKELQEKHKQEL 169
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIeelqkelyalaneISRLEQQKQILRERLANLERQLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   170 EDMRKAGHEAlsiivDEYKALLQsSVKQQVEAIEKQYISAIEKQAHKCEELLNAqhQRLLEMLDTEKELLKEKIKEALIQ 249
Cdd:TIGR02168  323 AQLEELESKL-----DELAEELA-ELEEKLEELKEELESLEAELEELEAELEEL--ESRLEELEEQLETLRSKVAQLELQ 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   250 QSQEQKEILE-----KCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEhakdqEKVSQE 324
Cdd:TIGR02168  395 IASLNNEIERlearlERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEAL-----EELREE 469

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 530399245   325 IQKAIQEQRKISQEtvkaaiiEEQKRSEKAVEEAVKRTRDELIEYIKEQK 374
Cdd:TIGR02168  470 LEEAEQALDAAERE-------LAQLQARLDSLERLQENLEGFSEGVKALL 512
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 157-383 5.72e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 5.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   157 RYKELQEKhKQELEdmrkagheaLSIIVDEYKALLQssvkqQVEAIEKQyISAIEKQAHKCEELLNAQHQRLLEMLDTEK 236
Cdd:TIGR02169  212 RYQALLKE-KREYE---------GYELLKEKEALER-----QKEAIERQ-LASLEEELEKLTEEISELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   237 ELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEAlvsAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELwkTEHAK 316
Cdd:TIGR02169  276 ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIA---EKERELEDAEERLAKLEAEIDKLLAEIEELEREI--EEERK 350

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530399245   317 DQEKVSQEIQKAIQEQRKISQEtvkaaiIEEqkrsekaVEEAVKRTRDELIEYikeQKRLDQVIRQR 383
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAE------LEE-------VDKEFAETRDELKDY---REKLEKLKREI 401
PTZ00121 PTZ00121
MAEBL; Provisional
 159-382 1.07e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  159 KELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKEL 238
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADE 1319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  239 LKEKIKEALiQQSQEQKEILEKCLEEERQRNKEALVSAAKLEK-EAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAK- 316
Cdd:PTZ00121 1320 AKKKAEEAK-KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAaEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKk 1398

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  317 ---DQEKVSQEIQKAIQEQRKISQETVKAaiiEEQKRSEKAVEEAV-KRTRDELIEYIKEQKRLDQVIRQ 382
Cdd:PTZ00121 1399 kaeEDKKKADELKKAAAAKKKADEAKKKA---EEKKKADEAKKKAEeAKKADEAKKKAEEAKKAEEAKKK 1465
PTZ00121 PTZ00121
MAEBL; Provisional
 135-379 1.10e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  135 KHNVLEKGFLKEKEQEAISFQDRYKelQEKHKQELEDMRKAghEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQA 214
Cdd:PTZ00121 1279 KADELKKAEEKKKADEAKKAEEKKK--ADEAKKKAEEAKKA--DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  215 HKcEELLNAQHQRLLEMLDTEKEllkEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEE 294
Cdd:PTZ00121 1355 AA-DEAEAAEEKAEAAEKKKEEA---KKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEK 1430

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  295 ERKNLEKAHAEERElwKTEHAK---DQEKVSQEIQKAIQEQRKISQETVKAaiiEEQKRSEKAVEEA--VKRTRDELIEY 369
Cdd:PTZ00121 1431 KKADEAKKKAEEAK--KADEAKkkaEEAKKAEEAKKKAEEAKKADEAKKKA---EEAKKADEAKKKAeeAKKKADEAKKA 1505

                         250
                  ....*....|
gi 530399245  370 IKEQKRLDQV 379
Cdd:PTZ00121 1506 AEAKKKADEA 1515
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 103-311 1.80e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   103 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKhnvlekgfLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSI 182
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAE--------LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   183 ivdeykALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEaliqqsQEQKEILEKCL 262
Cdd:TIGR02168  399 ------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE------LERLEEALEEL 466

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 530399245   263 EEERQRNKEALVSAAklEKEAVKDAVLKVVEEERKNLEKAHAEERELWK 311
Cdd:TIGR02168  467 REELEEAEQALDAAE--RELAQLQARLDSLERLQENLEGFSEGVKALLK 513
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 103-367 2.71e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.75  E-value: 2.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 103 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKgFLKEKEQEAISFQDRYKELQEKHKQeledmrkaghealsi 182
Cdd:COG4942   31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-RIRALEQELAALEAELAELEKEIAE--------------- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 183 ivdeykalLQSSVKQQVEAIEKQYISAIEKQAHKCEELL-----NAQHQRLLEMLDTEKELLKEKIKEalIQQSQEQKEI 257
Cdd:COG4942   95 --------LRAELEAQKEELAELLRALYRLGRQPPLALLlspedFLDAVRRLQYLKYLAPARREQAEE--LRADLAELAA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 258 LEKCLEEERQRnkealvsaaklekeavKDAVLKVVEEERKNLEKAHAEERELwKTEHAKDQEKVSQEIQKAIQEQRKIsQ 337
Cdd:COG4942  165 LRAELEAERAE----------------LEALLAELEEERAALEALKAERQKL-LARLEKELAELAAELAELQQEAEEL-E 226

                        250       260       270
                 ....*....|....*....|....*....|
gi 530399245 338 ETVKAAIIEEQKRSEKAVEEAVKRTRDELI 367
Cdd:COG4942  227 ALIARLEAEAAAAAERTPAAGFAALKGKLP 256
PTZ00121 PTZ00121
MAEBL; Provisional
 170-378 5.01e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.35  E-value: 5.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  170 EDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQyisaieKQAHKCEELLNAQHQRLLEMLDTEKELLKekiKEALIQ 249
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKA------EEERKAEEARKAEDAKKAEAVKKAEEAKK---DAEEAK 1243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  250 QSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERElwKTEHAK---DQEKVSQEIQ 326
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK--KADEAKkkaEEAKKADEAK 1321

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 530399245  327 KAIQEQRKISQETVKAAiiEEQKRSEKAVEEAVKRTRDELiEYIKEQKRLDQ 378
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKA--EEAKKAAEAAKAEAEAAADEA-EAAEEKAEAAE 1370
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 166-288 5.70e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 39.04  E-value: 5.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 166 KQELEDMrKAGHEALSIIVDEYKALLQSsVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKE 245
Cdd:PRK00409 515 KEKLNEL-IASLEELERELEQKAEEAEA-LLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKE 592

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 530399245 246 ALIQQSQEQKEILEKCLEEERQRNKEAL--VSAAKLEKEAVKDAV 288
Cdd:PRK00409 593 LRQLQKGGYASVKAHELIEARKRLNKANekKEKKKKKQKEKQEEL 637
PRK12704 PRK12704
phosphodiesterase; Provisional
 109-295 8.81e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 38.22  E-value: 8.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 109 SSLEIKLKVSEEEKQRIKQDVESLMEKHNvlekgflKEKEQEAisfQDRYKELQEKHKQELEDMRKaghealsiivdEYK 188
Cdd:PRK12704  27 KIAEAKIKEAEEEAKRILEEAKKEAEAIK-------KEALLEA---KEEIHKLRNEFEKELRERRN-----------ELQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245 189 ALlQSSVKQQVEAIEKQyisaiekqahkcEELLNAQHQRLLEmldtekellKEKIKEALIQQSQEQKEILEKCLEEERQR 268
Cdd:PRK12704  86 KL-EKRLLQKEENLDRK------------LELLEKREEELEK---------KEKELEQKQQELEKKEEELEELIEEQLQE 143

                        170       180
                 ....*....|....*....|....*..
gi 530399245 269 nkeaLVSAAKLEKEAVKDAVLKVVEEE 295
Cdd:PRK12704 144 ----LERISGLTAEEAKEILLEKVEEE 166
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 114-330 9.20e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 38.18  E-value: 9.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  114 KLKVSEEEKQRIKQDVESLMEKhnvlekgfLKEKEQEAisFQDRYKELQEKHKQELEDMRKaghealsiivDEYKALLQS 193
Cdd:pfam17380 403 KVKILEEERQRKIQQQKVEMEQ--------IRAEQEEA--RQREVRRLEEERAREMERVRL----------EEQERQQQV 462

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  194 SVKQQVEAIEKQYISAIEKQAHKcEELLNAQHQRLLE--MLDTEKELLKEKIKEALIQQSQE--QKEILEkclEEERQRN 269
Cdd:pfam17380 463 ERLRQQEEERKRKKLELEKEKRD-RKRAEEQRRKILEkeLEERKQAMIEEERKRKLLEKEMEerQKAIYE---EERRREA 538

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530399245  270 KEALVSAAKLEKEAVKDAVLKVVEEERKNLEkahAEERELWKTEHAKDQEKVSQEIQKAIQ 330
Cdd:pfam17380 539 EEERRKQQEMEERRRIQEQMRKATEERSRLE---AMEREREMMRQIVESEKARAEYEATTP 596
Mitofilin pfam09731
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...
 92-304 9.44e-03

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.


Pssm-ID: 430783 [Multi-domain]  Cd Length: 618  Bit Score: 38.20  E-value: 9.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245   92 SEDPGANVSNIQLQQKISSLEIKLKV-SEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELE 170
Cdd:pfam09731 225 PEHLDNVEEKVEKAQSLAKLVDQYKElVASERIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSLIAHAHREIDQLSKKLA 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399245  171 DMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEK----QAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEA 246
Cdd:pfam09731 305 ELKKREEKHIERALEKQKEELDKLAEELSARLEEVRAADEAQlrleFEREREEIRESYEEKLRTELERQAEAHEEHLKDV 384

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530399245  247 LIQQSQE----QKEILEKCLEEERQRNKEALvSAAKLEKEAVKDAVLKVVEEERKNLeKAHA 304
Cdd:pfam09731 385 LVEQEIElqreFLQDIKEKVEEERAGRLLKL-NELLANLKGLEKATSSHSEVEDENR-KAQQ 444
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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