|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
10-184 |
2.16e-74 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 244.74 E-value: 2.16e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 10 RGFLSGSLATWALGLAGLVGEAEESAGGTEEEEEEeeeeGALCTEKRFLRLIDGALLLRVLGIIAPSSRGGLRMvRGRDG 89
Cdd:cd22230 1 EEFMSGALVTWALGFEGLVGEEEDSLGFPEEEEEE----GTLDAEKRFLRLSNGDLLNRVMGIIDPSPRGGPRM-RGDDG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 90 PAACRMWNLCHLWGRLRDFYQEELQLLILSPPPDLQTMGCDPFSEEAVDELESILRLLLGASVQCEHRELFIRHIRGLSL 169
Cdd:cd22230 76 PAAHRVQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDL 155
|
170
....*....|....*
gi 755563857 170 DVQSELAGAIQEVTQ 184
Cdd:cd22230 156 DVQAELAEAIQEVTQ 170
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
12-184 |
8.70e-43 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 153.13 E-value: 8.70e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 12 FLSGSLATWALGLAGLVGEaeesaggteeeeeeeeeegalctEKRFLRLIDGALLLRVLGIIAPSSRGgLRMVRGRDGPA 91
Cdd:cd22223 1 FLSSPLVTWAKTFADDGSA-----------------------ELSYTDLVDGVFLNNVMLQIDPRPFS-EVSNRNVDDDV 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 92 ACRMWNLCHLWGRLRDFYQEELQLLILSPPPDLQTMGCDPFSEEAVDELESILRLLLGASVQCEHRELFIRHIRGLSLDV 171
Cdd:cd22223 57 NARIQNLDLLLRNIKSFYQEVLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEV 136
|
170
....*....|...
gi 755563857 172 QSELAGAIQEVTQ 184
Cdd:cd22223 137 QHALVACIQEVTD 149
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
733-1302 |
2.28e-28 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 124.28 E-value: 2.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 733 QALRDEVAQLRREVAGLEVK-LQAQAQRLEARSAEalcLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEA 811
Cdd:COG1196 216 RELKEELKELEAELLLLKLReLEAELEELEAELEE---LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 812 ASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGD 891
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 892 RLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALmELKARALQLEEELIQLRQypvdlATGA 971
Cdd:COG1196 373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE-ELEEALAELEEEEEEEEE-----ALEE 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 972 RAgprtvETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQEL 1051
Cdd:COG1196 447 AA-----EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1052 HRKLGVLEEEVRAARRAQEETRGQqqallrdhEALVQLQRRQETELEGLLVRHRDLKANmRALELAHRELQGRHEQLQAQ 1131
Cdd:COG1196 522 LAGAVAVLIGVEAAYEAALEAALA--------AALQNIVVEDDEVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1132 RANVEAQEVALLAERERLMQDGHRQRGLEEELRRLqnEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQ 1211
Cdd:COG1196 593 ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL--VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1212 SQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRR 1291
Cdd:COG1196 671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750
|
570
....*....|.
gi 755563857 1292 EKQKLVEKIMD 1302
Cdd:COG1196 751 EALEELPEPPD 761
|
|
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
57-184 |
6.97e-23 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 96.78 E-value: 6.97e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 57 FLRLIDGALLLRVLGIIAPSSRGGlRMVRGRDGPAACRMWNLCHLWGRLRDFYQEELQLLILSPPPDLQTMGCDPFSEEA 136
Cdd:cd22229 30 YVALVDGVFLNEVMLQINPKSSNQ-RVNKKVNNDASLRIQNLSILVKQIKLYYQETLQQLIMMSLPNVLVLGRNPLSEQG 108
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 755563857 137 VDELESILRLLLGASVQCEHRELFIRHIRGLSLDVQSELAGAIQEVTQ 184
Cdd:cd22229 109 TEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
202-960 |
1.72e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 102.06 E-value: 1.72e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 202 VAEELEMQLRSLTGMMSRLARERDLGAQ------RLAELLLEREPAHLLLPEAPANASAEGVsHHLALQLTNAKAQLRRL 275
Cdd:TIGR02168 194 ILNELERQLKSLERQAEKAERYKELKAElrelelALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 276 RQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAG-RLPRLQEELRRCREKLQAAEV- 353
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELEsKLDELAEELAELEEKLEELKEe 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 354 ---FKGQLEEERVLSEALEASKVLLEEQLEvarERSARLHETQRENLLLRTRLGEAHADLDSLRHQLEQLVEENVELELE 430
Cdd:TIGR02168 353 lesLEAELEELEAELEELESRLEELEEQLE---TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 431 LQR------SLEPPPGSPGEASLPGAAPSLQDEVREAEAgRLRAVERENRELRGQLQMLQAQLGSqhplLEEQRENSRQP 504
Cdd:TIGR02168 430 LEEaelkelQAELEELEEELEELQEELERLEEALEELRE-ELEEAEQALDAAERELAQLQARLDS----LERLQENLEGF 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 505 PVPNRDPATPSALHHSPQSPACQI-----GGEGSESLDLPSPASYSDITRSPKCSQAPDSHPELESPLQMVSQDPQTSDQ 579
Cdd:TIGR02168 505 SEGVKALLKNQSGLSGILGVLSELisvdeGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 580 ALQESDPTVethqcLEKSGHRVPLQSPIVWDPPQGP--------EVRI-----EVQELLGETGSREA---PQGELVHKAQ 643
Cdd:TIGR02168 585 EIQGNDREI-----LKNIEGFLGVAKDLVKFDPKLRkalsyllgGVLVvddldNALELAKKLRPGYRivtLDGDLVRPGG 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 644 VL--------------KQESPKCRPRSAELT-----LREPLKDQKALDRELELSKQQKETGRHEQRPKGLESKLGPQKPQ 704
Cdd:TIGR02168 660 VItggsaktnssilerRREIEELEEKIEELEekiaeLEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE 739
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 705 QTSEGVPDAWSREEptpgETLVSAIPEEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEA 784
Cdd:TIGR02168 740 AEVEQLEERIAQLS----KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 785 HQEAEAQAREQARLREAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESqvrcHLEE 864
Cdd:TIGR02168 816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE----ALAL 891
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 865 AEREHAEKQALREELEKAVlrgQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALM 944
Cdd:TIGR02168 892 LRSELEELSEELRELESKR---SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968
|
810
....*....|....*.
gi 755563857 945 ELKARALQLEEELIQL 960
Cdd:TIGR02168 969 EARRRLKRLENKIKEL 984
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
731-1223 |
3.53e-21 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 100.78 E-value: 3.53e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAglevKLQAQAQRLEARSAEalcLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:COG1196 282 ELEEAQAEEYELLAELA----RLEQDIARLEERRRE---LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELG 890
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAALERQKfLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVD-LAT 969
Cdd:COG1196 435 EEEEEEEEALEEAAEEEAE-LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAA 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 970 GARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQ----------LQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQA 1039
Cdd:COG1196 514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQnivveddevaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1040 EKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHR 1119
Cdd:COG1196 594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1120 ELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLA 1199
Cdd:COG1196 674 LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753
|
490 500
....*....|....*....|....
gi 755563857 1200 RLELERAQLEIQSQQLRESNQQLD 1223
Cdd:COG1196 754 EELPEPPDLEELERELERLEREIE 777
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
839-1293 |
5.77e-21 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 100.40 E-value: 5.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 839 RLRAQVEAAEQ----QVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQ 914
Cdd:COG1196 204 PLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 915 ENQHQRYRHLEQRLEaELQAASTSKEEALMELKARALQLEEELIQLRQypvdlatgaragprtvetqngRLIEVERNNAT 994
Cdd:COG1196 284 EEAQAEEYELLAELA-RLEQDIARLEERRRELEERLEELEEELAELEE---------------------ELEELEEELEE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 995 LVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRG 1074
Cdd:COG1196 342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1075 QQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGH 1154
Cdd:COG1196 422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1155 RQRGLEEELRRLQNEhERAQMLLAEVSRERGELQGERGELRSRLARLeLERAQLEIQSQQLRESNQQLDLSACRLTTQCE 1234
Cdd:COG1196 502 DYEGFLEGVKAALLL-AGLRGLAGAVAVLIGVEAAYEAALEAALAAA-LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755563857 1235 LLTQLRSAQEEENRQL--LAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREK 1293
Cdd:COG1196 580 DKIRARAALAAALARGaiGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
731-1300 |
5.79e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 97.05 E-value: 5.79e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLrgQELG 890
Cdd:TIGR02168 362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQ 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRL---EAELQAAStSKEEALMELKARALQLEEELIQLRQY---- 963
Cdd:TIGR02168 440 AELEELEEELEELQEELERLEEALEELREELEEAEQALdaaERELAQLQ-ARLDSLERLQENLEGFSEGVKALLKNqsgl 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 964 -------------------PVDLATGARAGPRTVETQN--------------------------GRLIEVERNNAT---- 994
Cdd:TIGR02168 519 sgilgvlselisvdegyeaAIEAALGGRLQAVVVENLNaakkaiaflkqnelgrvtflpldsikGTEIQGNDREILknie 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 995 --------LVAEKAALQGQLQHLEGQL---GSLQGrAQELLLQSQ----------------------RAQEHSSRLQAEK 1041
Cdd:TIGR02168 599 gflgvakdLVKFDPKLRKALSYLLGGVlvvDDLDN-ALELAKKLRpgyrivtldgdlvrpggvitggSAKTNSSILERRR 677
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1042 SMmemqgQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLlvrhrdlKANMRALELAHREL 1121
Cdd:TIGR02168 678 EI-----EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL-------RKDLARLEAEVEQL 745
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1122 QGRHEQLQAQRANVEAQEVALLAERERLMQDGHRqrgLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARL 1201
Cdd:TIGR02168 746 EERIAQLSKELTELEAEIEELEERLEEAEEELAE---AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1202 ELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLH---RE 1278
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEelsEE 902
|
650 660
....*....|....*....|..
gi 755563857 1279 QREYLDQLNALRREKQKLVEKI 1300
Cdd:TIGR02168 903 LRELESKRSELRRELEELREKL 924
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
731-1209 |
6.62e-20 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 96.93 E-value: 6.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAglevKLQAQAQRLEARSAEALclsEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:COG1196 310 RRRELEERLEELEEELA----ELEEELEELEEELEELE---EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELG 890
Cdd:COG1196 383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLrQYPVDLATG 970
Cdd:COG1196 463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV-EAAYEAALE 541
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 971 ARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQE 1050
Cdd:COG1196 542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1051 LHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQA 1130
Cdd:COG1196 622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755563857 1131 QRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLE 1209
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
12-184 |
1.49e-17 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 81.12 E-value: 1.49e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 12 FLSGSLATWALGLAGLVGEAEESAGgteeeeeeeeeegalctekRFLRLIDGALLLRVLGIIAPSSRGGlRMVRGRDGPA 91
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLS-------------------MYMDLVDGVFLNKIMLQIDPRPTNQ-RVNKHVNNDV 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 92 ACRMWNLCHLWGRLRDFYQEELQLLILSPPPDLQTMGCDPFSEEAVDELESILRLLLGASVQCEHRELFIRHIRGLSLDV 171
Cdd:cd22228 61 NLRIQNLTILVRHIKTYYQEVLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIET 140
|
170
....*....|...
gi 755563857 172 QSELAGAIQEVTQ 184
Cdd:cd22228 141 QAAIVSHIQEVTH 153
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1049-1308 |
2.19e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.46 E-value: 2.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1049 QELHRKLGVLEEEVRAARRAQE-----ETRGQQQALLRDHEALVQLQRRQ------ETELEGLLVRHRDLKANMRALELA 1117
Cdd:COG1196 196 GELERQLEPLERQAEKAERYRElkeelKELEAELLLLKLRELEAELEELEaeleelEAELEELEAELAELEAELEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1118 HRELQGRHEQLQAQRANVEAQ----EVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGE 1193
Cdd:COG1196 276 LEELELELEEAQAEEYELLAElarlEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1194 LRSRLA-----RLELERAQLEIQSQQLRESNQQLDLsacrLTTQCELLTQLRSA--QEEENRQLLAEVQALSRENRELLE 1266
Cdd:COG1196 356 AEAELAeaeeaLLEAEAELAEAEEELEELAEELLEA----LRAAAELAAQLEELeeAEEALLERLERLEEELEELEEALA 431
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 755563857 1267 RSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLE 1308
Cdd:COG1196 432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
885-1208 |
4.18e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 87.80 E-value: 4.18e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 885 RGQELgDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELK---ARALQLEEELIQLR 961
Cdd:TIGR02168 675 RRREI-EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLArleAEVEQLEERIAQLS 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 962 QYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEK 1041
Cdd:TIGR02168 754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1042 SMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHREL 1121
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1122 QGRHEQLQAQRANVEAQEVALLAERERlmqdghrqrgLEEELRrlqnehERAQMLLAEVSRERGELQGERGELRSRLARL 1201
Cdd:TIGR02168 914 RRELEELREKLAQLELRLEGLEVRIDN----------LQERLS------EEYSLTLEEAEALENKIEDDEEEARRRLKRL 977
|
....*..
gi 755563857 1202 ELERAQL 1208
Cdd:TIGR02168 978 ENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
616-1317 |
1.85e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 82.41 E-value: 1.85e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 616 EVRIEVQELLGETGSREAPQGELVHKAQVLKQESPKC--RPRSAELTLREPLKDQKALDRELELSKQQKEtgRHEQRPKG 693
Cdd:TIGR02168 264 ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeqQKQILRERLANLERQLEELEAQLEELESKLD--ELAEELAE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 694 LESKLGPQKPQQTSEGVPDAWSREEPTPGETLVSAIPEE-QALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSE 772
Cdd:TIGR02168 342 LEEKLEELKEELESLEAELEELEAELEELESRLEELEEQlETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 773 ELAQARRteAEAHQEAEAQAREQARLREAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQ 852
Cdd:TIGR02168 422 EIEELLK--KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 853 ALES---QVRCHLEEAEREHAEKQAL------REELEKAVLrgQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRH 923
Cdd:TIGR02168 500 NLEGfseGVKALLKNQSGLSGILGVLselisvDEGYEAAIE--AALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLP 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 924 LEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQ---------YPVD-LATGARAGPRT---------------- 977
Cdd:TIGR02168 578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvLVVDdLDNALELAKKLrpgyrivtldgdlvrp 657
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 978 --------VETQNGRLiEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQ 1049
Cdd:TIGR02168 658 ggvitggsAKTNSSIL-ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1050 ELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQ 1129
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN 816
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1130 AQRANVEAQEVALLAERERLMQdghRQRGLEEELRRLQNEheraqmlLAEVSRERGELQGERGELRSRLARLELERAQLE 1209
Cdd:TIGR02168 817 EEAANLRERLESLERRIAATER---RLEDLEEQIEELSED-------IESLAAEIEELEELIEELESELEALLNERASLE 886
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1210 IQSQQLRESNQQLDlsacrlttqcelltqlrsaqeeenrqllAEVQALSRENRELLERSLESRDHLHREQReyldQLNAL 1289
Cdd:TIGR02168 887 EALALLRSELEELS----------------------------EELRELESKRSELRRELEELREKLAQLEL----RLEGL 934
|
730 740
....*....|....*....|....*...
gi 755563857 1290 RREKQKLVEKIMDQYRVLEPGPLPRTKK 1317
Cdd:TIGR02168 935 EVRIDNLQERLSEEYSLTLEEAEALENK 962
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
863-1218 |
3.45e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 81.65 E-value: 3.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 863 EEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAalERQKFLQEQENQHQRYRHLeqrleAELQAASTSKEEA 942
Cdd:TIGR02169 170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA--ERYQALLKEKREYEGYELL-----KEKEALERQKEAI 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 943 LMELKAralqLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEK-AALQGQLQHLEGQLGSLQGRAQ 1021
Cdd:TIGR02169 243 ERQLAS----LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELE 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1022 ELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLL 1101
Cdd:TIGR02169 319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1102 VRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERlmqdghrqrgLEEELRRLQNEHERAQMLLAEVS 1181
Cdd:TIGR02169 399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKED----------KALEIKKQEWKLEQLAADLSKYE 468
|
330 340 350
....*....|....*....|....*....|....*..
gi 755563857 1182 RERGELQGERGELRSRLARLELERAQLEIQSQQLRES 1218
Cdd:TIGR02169 469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
60-184 |
9.84e-15 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 72.69 E-value: 9.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 60 LIDGALLLRVLGIIAPSS-RGGLRMVRGRDGPAACRMWNLCHLWGRLRDFYQEEL-QLLILSPPPDLQTMgcdpFSEEAV 137
Cdd:cd22211 23 LSDGVVLAEILSQIDPSYfDSEWLESRDSSDNWVLKLNNLKKLYRSLSKYYREVLgQQLSDLPLPDLSAI----ARDGDE 98
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 755563857 138 DELESILRLLLGASVQCEHRELFIRHIRGLSLDVQSELAGAIQEVTQ 184
Cdd:cd22211 99 EEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
839-1144 |
2.93e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 2.93e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 839 RLRAQVEAAEQQVQALESQvrchLEEAEREHAEKQALREELEKAVlrgQELGDRLEHLQEEL-----EQAALERQK-FLQ 912
Cdd:TIGR02168 236 ELREELEELQEELKEAEEE----LEELTAELQELEEKLEELRLEV---SELEEEIEELQKELyalanEISRLEQQKqILR 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 913 EQENQHQR--------YRHLEQRLEaELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGR 984
Cdd:TIGR02168 309 ERLANLERqleeleaqLEELESKLD-ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 985 LIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELL--LQSQRAQEHSSRLQAEKsmmemqgQELHRKLGVLEEEV 1062
Cdd:TIGR02168 388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLkkLEEAELKELQAELEELE-------EELEELQEELERLE 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1063 RAARRAQEETRGQQQALLRDHEALVQLQRRQETeLEGLLVRHRDLKANMRALELAHRELQGRHEQLqAQRANVEAQ-EVA 1141
Cdd:TIGR02168 461 EALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVL-SELISVDEGyEAA 538
|
...
gi 755563857 1142 LLA 1144
Cdd:TIGR02168 539 IEA 541
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
839-1300 |
3.12e-14 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 78.42 E-value: 3.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 839 RLRAQVEAAEQQVQALEsQVRCHLEEAEREHAEKQALREELEK-----AVLRGQELGDRLEHLQEELEQAALERQKFLQE 913
Cdd:COG4913 239 RAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAAlrlwfAQRRLELLEAELEELRAELARLEAELERLEAR 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 914 QENQHQRYRHLEQRL-------EAELQAASTSKEEALMELKARALQLEEELIQLRQYPV----DLATGARAGPRTVETQN 982
Cdd:COG4913 318 LDALREELDELEAQIrgnggdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPasaeEFAALRAEAAALLEALE 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 983 GRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEhssrlqaeksmmemqgqELHRKLGVLEEEV 1062
Cdd:COG4913 398 EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD-----------------ALAEALGLDEAEL 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1063 RAA------RRAQEETRGQQQALLRDhealvqlQRRqeteleGLLVRHRDLKANMRALElaHRELQGRHEQLQAQRANVE 1136
Cdd:COG4913 461 PFVgelievRPEEERWRGAIERVLGG-------FAL------TLLVPPEHYAAALRWVN--RLHLRGRLVYERVRTGLPD 525
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1137 AQEVALLAER--ERLMQDGHRQRG-LEEELRRLQN-----------EHERAQMLLAEV--SRERGELQGERGELR----- 1195
Cdd:COG4913 526 PERPRLDPDSlaGKLDFKPHPFRAwLEAELGRRFDyvcvdspeelrRHPRAITRAGQVkgNGTRHEKDDRRRIRSryvlg 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1196 ----SRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEEN--RQLLAEVQALSRENRELLE--- 1266
Cdd:COG4913 606 fdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLDAssd 685
|
490 500 510
....*....|....*....|....*....|....*..
gi 755563857 1267 --RSLESR-DHLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:COG4913 686 dlAALEEQlEELEAELEELEEELDELKGEIGRLEKEL 722
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1009-1327 |
5.33e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 5.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1009 LEGQLGSLQGRAQelllQSQRAQEHSSRL-QAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALV 1087
Cdd:TIGR02168 198 LERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1088 QLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRqrgLEEELRRLQ 1167
Cdd:TIGR02168 274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE---LEEKLEELK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1168 NEHE-------RAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLR 1240
Cdd:TIGR02168 351 EELEsleaeleELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1241 SAQE--------EENRQLLAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALrREKQKLVEKIMDQYRVLEPGPL 1312
Cdd:TIGR02168 431 EEAElkelqaelEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL-QARLDSLERLQENLEGFSEGVK 509
|
330
....*....|....*
gi 755563857 1313 PRTKKGSWLADKGPR 1327
Cdd:TIGR02168 510 ALLKNQSGLSGILGV 524
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
731-1308 |
6.73e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 77.42 E-value: 6.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLE---VKLQAQAQRLEARSAEALCLSEELAqarrteaeaHQEAEAQAREQARLREAVDTASL 807
Cdd:TIGR02169 231 EKEALERQKEAIERQLASLEeelEKLTEEISELEKRLEEIEQLLEELN---------KKIKDLGEEEQLRVKEKIGELEA 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 808 ELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQ 887
Cdd:TIGR02169 302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 888 ELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLeAELQAASTSKEEALMELKARALQLEEEliqlrqypvdl 967
Cdd:TIGR02169 382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL-ADLNAAIAGIEAKINELEEEKEDKALE----------- 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 968 atgaragprtVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQ 1047
Cdd:TIGR02169 450 ----------IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1048 GQELH---RKLGVLEE------EVRAARRAQ------EETRGQQQALLRDHEA----LVQLQRRQETELEG--------- 1099
Cdd:TIGR02169 520 IQGVHgtvAQLGSVGEryataiEVAAGNRLNnvvvedDAVAKEAIELLKRRKAgratFLPLNKMRDERRDLsilsedgvi 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1100 ------------------------LLVRH----RDLKANMRALEL----------------AHRELQGRHEQLQAQRANV 1135
Cdd:TIGR02169 600 gfavdlvefdpkyepafkyvfgdtLVVEDieaaRRLMGKYRMVTLegelfeksgamtggsrAPRGGILFSRSEPAELQRL 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1136 EAQEVALLAERERLMQDGHRQRG------------------LEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSR 1197
Cdd:TIGR02169 680 RERLEGLKRELSSLQSELRRIENrldelsqelsdasrkigeIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1198 LARLELERAQLEIQSQQLREsnQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQAL-SRENRELLERSL--ESRDH 1274
Cdd:TIGR02169 760 LKELEARIEELEEDLHKLEE--ALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIeQKLNRLTLEKEYleKEIQE 837
|
650 660 670
....*....|....*....|....*....|....
gi 755563857 1275 LHREQREYLDQLNALRREKQKLVEKIMDQYRVLE 1308
Cdd:TIGR02169 838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
876-1259 |
1.19e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.63 E-value: 1.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 876 REELEKAVLRGQELGDRLEHLQEELEqaalERQKFLQEQENQHQRYRHLEQRLEaELQAASTSKEeaLMELKARALQLEE 955
Cdd:TIGR02168 174 RKETERKLERTRENLDRLEDILNELE----RQLKSLERQAEKAERYKELKAELR-ELELALLVLR--LEELREELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 956 ELIQLRQypvdlatgaragprtvetqngrlievernnatlvaEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSS 1035
Cdd:TIGR02168 247 ELKEAEE-----------------------------------ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1036 RLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALE 1115
Cdd:TIGR02168 292 ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1116 LAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRqrgLEEELRRLQNEHE--RAQMLLAEVSRERGELQGERGE 1193
Cdd:TIGR02168 372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLER---LEDRRERLQQEIEelLKKLEEAELKELQAELEELEEE 448
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755563857 1194 LRSRLARLELERAQLEIQSQQLRESNQQLDL---SACRLTTQCELLTQLRSAQEEENRQLLAEVQALSR 1259
Cdd:TIGR02168 449 LEELQEELERLEEALEELREELEEAEQALDAaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG 517
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
261-499 |
5.50e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.20 E-value: 5.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 261 LALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQ--AKRAELYREEAEALRERAGRLP--- 335
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEleEAQAEEYELLAELARLEQDIARlee 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 336 -------RLQEELRRCREKLQAAEVFKGQLEEERVLSEALEASKVLLEEQLEVARERSARLHETQREnlLLRTRLGEAHA 408
Cdd:COG1196 310 rrreleeRLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE--AEEELEELAEE 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 409 DLDSLRHQLEQLVEENVELELELQRSLEpppgspgEASLPGAAPSLQDEVREAEAGRLRAVERENRELRGQLQMLQAQLG 488
Cdd:COG1196 388 LLEALRAAAELAAQLEELEEAEEALLER-------LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460
|
250
....*....|.
gi 755563857 489 SQHPLLEEQRE 499
Cdd:COG1196 461 LLELLAELLEE 471
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
857-1209 |
9.84e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.56 E-value: 9.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 857 QVRCHLEEAEREhaeKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEaELQAAS 936
Cdd:TIGR02169 678 RLRERLEGLKRE---LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEI 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 937 TSKEEALMELKARALQLEEELIQLRQYPVDLAtgARAGPRTVETQNGRLIEVErnnatlvAEKAALQGQLQHLEGQLGSL 1016
Cdd:TIGR02169 754 ENVKSELKELEARIEELEEDLHKLEEALNDLE--ARLSHSRIPEIQAELSKLE-------EEVSRIEARLREIEQKLNRL 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1017 QGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDhealvqlQRRQETE 1096
Cdd:TIGR02169 825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE-------RDELEAQ 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1097 LEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQ---RGLEEELRRLQNEHERA 1173
Cdd:TIGR02169 898 LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQaelQRVEEEIRALEPVNMLA 977
|
330 340 350
....*....|....*....|....*....|....*.
gi 755563857 1174 QMLLAEVSRERGELQGERgelrsrlARLELERAQLE 1209
Cdd:TIGR02169 978 IQEYEEVLKRLDELKEKR-------AKLEEERKAIL 1006
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
60-182 |
1.73e-12 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 66.50 E-value: 1.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 60 LIDGALLLRVLGIIAPSSRGGLRMVRGRDGPA---ACRMWNLCHLWGRLRDFYQEEL-QLLILSPPPDLQTMG--CDPfs 133
Cdd:cd22222 23 LSDGVAIAQVLNQIDPEYFSDSWLSKIKPDVGdnwRLKVSNLKKILKGIVDYYSEVLgQQISGFTMPDVNAIAekEDP-- 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 755563857 134 eeavDELESILRLLLGASVQCEHRELFIRHIRGLSLDVQSELAGAIQEV 182
Cdd:cd22222 101 ----KELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
643-1269 |
3.24e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 71.61 E-value: 3.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 643 QVLKQESPKCRPRSAELTLREPLKDQKALDRELELSKQQKETGRHEQRPKGLESKLgpqkpqQTSEGVPDAWSREEPTPG 722
Cdd:PRK02224 160 QLGKLEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESEL------AELDEEIERYEEQREQAR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 723 ETLVSA---IPEEQALRDEVAQLRREVAGLEVKLQAQAQRLEArsaealcLSEELAQARRTEAEAHQeaeaqarEQARLR 799
Cdd:PRK02224 234 ETRDEAdevLEEHEERREELETLEAEIEDLRETIAETEREREE-------LAEEVRDLRERLEELEE-------ERDDLL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 800 EAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREEL 879
Cdd:PRK02224 300 AEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAV 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 880 EKAVLRGQELGDRLEHLQEELEQAALERQK---FLQEQENQHQRYRHLEQRLEAELQAASTSKEEalmelkARALQLEEE 956
Cdd:PRK02224 380 EDRREEIEELEEEIEELRERFGDAPVDLGNaedFLEELREERDELREREAELEATLRTARERVEE------AEALLEAGK 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 957 LIQLRQyPVDLATGAragpRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEgQLGSLQGRAQELLLQSQRAQEHSSR 1036
Cdd:PRK02224 454 CPECGQ-PVEGSPHV----ETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAE 527
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1037 LQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLlvrhRDLKANMRALEL 1116
Cdd:PRK02224 528 RRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL----ERIRTLLAAIAD 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1117 AHRELQGRHEQLqAQRANVEAQevallaERERLMQDGHRQRGLEEE-----LRRLQNEHERAQMLLAEVSRERGELQGER 1191
Cdd:PRK02224 604 AEDEIERLREKR-EALAELNDE------RRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREER 676
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755563857 1192 GELRSRLARLELERAQLEiqsqQLRESNQQLDLSACRLTTQCELLTQLrsaqEEENRQLLAEvqaLSRENRELLERSL 1269
Cdd:PRK02224 677 DDLQAEIGAVENELEELE----ELRERREALENRVEALEALYDEAEEL----ESMYGDLRAE---LRQRNVETLERML 743
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
770-1135 |
1.88e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.33 E-value: 1.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 770 LSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAASrerealaealaaagRERRQWERDGPRLRAQVEAAEQ 849
Cdd:TIGR02169 672 EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS--------------RKIGEIEKEIEQLEQEEEKLKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 850 QVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAAL-ERQKFLQEQENQHQRYRHLEQRL 928
Cdd:TIGR02169 738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRIEARLREI 817
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 929 EAELQAASTSKEealmelkaralQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQH 1008
Cdd:TIGR02169 818 EQKLNRLTLEKE-----------YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGD 886
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1009 LEG-------QLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVrAARRAQEETRGQQQALLR 1081
Cdd:TIGR02169 887 LKKerdeleaQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIP-EEELSLEDVQAELQRVEE 965
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 755563857 1082 DHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANV 1135
Cdd:TIGR02169 966 EIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
828-1248 |
2.35e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 68.64 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDGPRLRAQVEAAEQQVQALEsQVRCHLEEAEREHAEKQALREELEKAV------LRGQELGDRLEHLQ---E 898
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLqllplyQELEALEAELAELPerlE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 899 ELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQypvdlatgaragprTV 978
Cdd:COG4717 150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEE--------------EL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 979 ETQNGRLIEVERNNATLVAEKAALQgQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSR------LQAEKSMMEMQGQELH 1052
Cdd:COG4717 216 EEAQEELEELEEELEQLENELEAAA-LEERLKEARLLLLIAAALLALLGLGGSLLSLIltiagvLFLVLGLLALLFLLLA 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1053 RKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQgrHEQLQAQR 1132
Cdd:COG4717 295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEI 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1133 ANV--------EAQEVALLAERERLMQDGHRQRGLEEELR----------------RLQNEHERAQMLLAEVSRERGELQ 1188
Cdd:COG4717 373 AALlaeagvedEEELRAALEQAEEYQELKEELEELEEQLEellgeleellealdeeELEEELEELEEELEELEEELEELR 452
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755563857 1189 GERGELRSRLARLELER--AQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENR 1248
Cdd:COG4717 453 EELAELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
793-1303 |
4.01e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 68.17 E-value: 4.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 793 REQARLREAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRcHLEEAEREHAEK 872
Cdd:PRK03918 217 PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKELKEKAEEY 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 873 QALREELEKAVLRGQELGDRLEHLQEELEqaALERQkfLQEQENQHQRYRHLEQRLEAELQAASTSKEEAlmELKARALQ 952
Cdd:PRK03918 296 IKLSEFYEEYLDELREIEKRLSRLEEEIN--GIEER--IKELEEKEERLEELKKKLKELEKRLEELEERH--ELYEEAKA 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 953 LEEELIQLRqypvdlatgARAGPRTVETQNGRLIEVERnnatlvaEKAALQGQLQHLEGQLGSLQGRAQELllqsqraQE 1032
Cdd:PRK03918 370 KKEELERLK---------KRLTGLTPEKLEKELEELEK-------AKEEIEEEISKITARIGELKKEIKEL-------KK 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1033 HSSRLQAEKSMMEMQGQEL--HRKLGVLEEEVRAARRAQEEtrgqqqaLLRDHEALVQLqRRQETELEGLLVRHRDLKAN 1110
Cdd:PRK03918 427 AIEELKKAKGKCPVCGRELteEHRKELLEEYTAELKRIEKE-------LKEIEEKERKL-RKELRELEKVLKKESELIKL 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1111 MRALELAhRELQGRHEQLQAQRANVEAQEVALLaeRERLMQDGHRQRGLEEELRRLQ---NEHERAQMLLAEVSRERGEL 1187
Cdd:PRK03918 499 KELAEQL-KELEEKLKKYNLEELEKKAEEYEKL--KEKLIKLKGEIKSLKKELEKLEelkKKLAELEKKLDELEEELAEL 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1188 QGERG--------ELRSRLARLE-LERAQLEIQS--QQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQA 1256
Cdd:PRK03918 576 LKELEelgfesveELEERLKELEpFYNEYLELKDaeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 755563857 1257 LSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQ 1303
Cdd:PRK03918 656 YSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEE 702
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
731-1300 |
4.62e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 68.17 E-value: 4.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLEVKLQAQAQRLEArsaealcLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDK-------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELG 890
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAALERqkflqeqenqhqryrhleQRLEAELQAASTSKEE---ALMELKAR---ALQLEEELIQLR--- 961
Cdd:TIGR02169 476 EEYDRVEKELSKLQREL------------------AEAEAQARASEERVRGgraVEEVLKASiqgVHGTVAQLGSVGery 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 962 QYPVDLATGARAGPRTVET--------------QNGR------------------------------LIEVERNNA---- 993
Cdd:TIGR02169 538 ATAIEVAAGNRLNNVVVEDdavakeaiellkrrKAGRatflplnkmrderrdlsilsedgvigfavdLVEFDPKYEpafk 617
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 994 -----TLVAEKAAL------QGQLQHLEGQL---------GSLQGRAQELLLQSQRAQEhsSRLQAEKSMMEMQGQELHR 1053
Cdd:TIGR02169 618 yvfgdTLVVEDIEAarrlmgKYRMVTLEGELfeksgamtgGSRAPRGGILFSRSEPAEL--QRLRERLEGLKRELSSLQS 695
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1054 KLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRA 1133
Cdd:TIGR02169 696 ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLH 775
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1134 NVEAQEVALLAererlMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQsq 1213
Cdd:TIGR02169 776 KLEEALNDLEA-----RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ-- 848
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1214 qlRESNQQldlsacrltTQCELLTQLRSAQEEEnrqllaevqalsrENRELLERSLESR-DHLHREQREYLDQLNALRRE 1292
Cdd:TIGR02169 849 --IKSIEK---------EIENLNGKKEELEEEL-------------EELEAALRDLESRlGDLKKERDELEAQLRELERK 904
|
....*...
gi 755563857 1293 KQKLVEKI 1300
Cdd:TIGR02169 905 IEELEAQI 912
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
846-1300 |
6.07e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 67.40 E-value: 6.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 846 AAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLE 925
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 926 QRLEaelqaastSKEEALMELKARALQLEEeliqlrqypvdlatgaragprtvetqngrLIEVERNNATLVAEKAALQGQ 1005
Cdd:PRK03918 266 ERIE--------ELKKEIEELEEKVKELKE-----------------------------LKEKAEEYIKLSEFYEEYLDE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1006 LQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEmqgqELHRKLGVLEEEVRAARRAQeetrgqqqallrdheA 1085
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK----ELEKRLEELEERHELYEEAK---------------A 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1086 LVQLQRRQETELEGLLVrhRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEvallAERERLMQDGHRQRGLEEELRR 1165
Cdd:PRK03918 370 KKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITARIGELKKEI----KELKKAIEELKKAKGKCPVCGR 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1166 LQNEHERAQmLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLResnqqldlsacRLTTQCELLTQLRSAQEE 1245
Cdd:PRK03918 444 ELTEEHRKE-LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES-----------ELIKLKELAEQLKELEEK 511
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 755563857 1246 ENRQLLAEVQALSRENRELLERSLESRDHLHREQREyLDQLNALRREKQKLVEKI 1300
Cdd:PRK03918 512 LKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE-LEKLEELKKKLAELEKKL 565
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1019-1295 |
8.44e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 8.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1019 RAQELLLQSQRAQEHSSRLQAEKSmmemqgqELHRKLGVLEEEVRAARRAQEetrgqQQALLRDHEALVQLQR--RQETE 1096
Cdd:TIGR02168 173 RRKETERKLERTRENLDRLEDILN-------ELERQLKSLERQAEKAERYKE-----LKAELRELELALLVLRleELREE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1097 LEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALlaeRERLMQDGHRQRGLEEELRRLQNEHERAQML 1176
Cdd:TIGR02168 241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL---QKELYALANEISRLEQQKQILRERLANLERQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1177 LAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLR----ESNQQLDLSACRLTTQCELLTQLRSAQEEENRQlLA 1252
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEaeleELEAELEELESRLEELEEQLETLRSKVAQLELQ-IA 396
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 755563857 1253 EVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQK 1295
Cdd:TIGR02168 397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ 439
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
734-1305 |
9.87e-11 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 66.86 E-value: 9.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 734 ALRDEVAQLRREVAGLEvKLQAQAQRLEARSAEALCLSEELAQARrteaeahqeAEAQAREQARLREAVDTASLELEAAs 813
Cdd:COG4913 239 RAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALR---------LWFAQRRLELLEAELEELRAELARL- 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 814 rerealaealaaaGRERRQWERDGPRLRAQVEAAEQQ--------VQALESQvrchLEEAEREHAEKQALREELEKAVLR 885
Cdd:COG4913 308 -------------EAELERLEARLDALREELDELEAQirgnggdrLEQLERE----IERLERELEERERRRARLEALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 886 -GQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEaELQAASTSKEEALMELKARALQLEEELIQLRQYP 964
Cdd:COG4913 371 lGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALR-DLRRELRELEAEIASLERRKSNIPARLLALRDAL 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 965 VDLATGARAGPRTVetqnGRLIEVERNNA---------------TLVAEKAALQGQLQ-----HLEGQLGSLQGRAQELL 1024
Cdd:COG4913 450 AEALGLDEAELPFV----GELIEVRPEEErwrgaiervlggfalTLLVPPEHYAAALRwvnrlHLRGRLVYERVRTGLPD 525
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1025 LQSQRAQEHS--SRLQAEKSmmEMQG---QELHRKLGVL----EEEVRAARRA--------QEETRGQ---QQALLRDH- 1083
Cdd:COG4913 526 PERPRLDPDSlaGKLDFKPH--PFRAwleAELGRRFDYVcvdsPEELRRHPRAitragqvkGNGTRHEkddRRRIRSRYv 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1084 ---EALVQLQRRQEtELEGLLVRHRDLKANMRALELAHRELQGRHEQLQaQRANVEAQEVALLAERERLMQdghrqrgLE 1160
Cdd:COG4913 604 lgfDNRAKLAALEA-ELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDVASAEREIAE-------LE 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1161 EELRRL---QNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLResnqqldlsacrlttqcELLT 1237
Cdd:COG4913 675 AELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ-----------------DRLE 737
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1238 QLRSAQEEENRQLLAEV--QALSRENRELLERSLESRdhlhreqreyLDQLNALRREKQKLVEKIMDQYR 1305
Cdd:COG4913 738 AAEDLARLELRALLEERfaAALGDAVERELRENLEER----------IDALRARLNRAEEELERAMRAFN 797
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
851-1300 |
1.10e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 66.60 E-value: 1.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 851 VQALESQVRCHLEEAEREHAEKQA--LREELEKAVLRGQELGDRLEHLQEELEQAALERQK---FLQEQENQHQRYRHLE 925
Cdd:PRK02224 178 VERVLSDQRGSLDQLKAQIEEKEEkdLHERLNGLESELAELDEEIERYEEQREQARETRDEadeVLEEHEERREELETLE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 926 QRLEaELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQ 1005
Cdd:PRK02224 258 AEIE-DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1006 LQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRA---QEETRGQQQALLRD 1082
Cdd:PRK02224 337 AQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdAPVDLGNAEDFLEE 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1083 HEALVQLQRRQETELEGLLVRHRDLKANMRALELAHR------------------ELQGRHEQLQAQRANVEAQEVALLA 1144
Cdd:PRK02224 417 LREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVEE 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1145 ERERLMQdghrQRGLEEELRRLQNEHERAQMLLAEvSRERGElqgergELRSRLARLELERAQLEIQSQQLRESNQQLDL 1224
Cdd:PRK02224 497 RLERAED----LVEAEDRIERLEERREDLEELIAE-RRETIE------EKRERAEELRERAAELEAEAEEKREAAAEAEE 565
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755563857 1225 SACRLTTQCELLTQLRSAQEEENRQL--LAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:PRK02224 566 EAEEAREEVAELNSKLAELKERIESLerIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
997-1223 |
2.61e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 64.01 E-value: 2.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 997 AEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQ 1076
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1077 QALLRdhealvQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAqevallaererlmqdghrq 1156
Cdd:COG4942 107 AELLR------ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE------------------- 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755563857 1157 rgLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLD 1223
Cdd:COG4942 162 --LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
887-1300 |
3.69e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 3.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 887 QELGDRLEHLQEELEQAALERqkflqeqenqhqryRHLEQRLEAELQAASTSKEEaLMELKARALQLEEELiqlrqypvd 966
Cdd:TIGR02169 677 QRLRERLEGLKRELSSLQSEL--------------RRIENRLDELSQELSDASRK-IGEIEKEIEQLEQEE--------- 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 967 latgaragprtvETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELllqsqraQEHSSRLQAEKSMMEM 1046
Cdd:TIGR02169 733 ------------EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL-------EEALNDLEARLSHSRI 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1047 QgqELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALvqlqrrqETELEGLLVRHRDLKANMRALELAHRELQGRHE 1126
Cdd:TIGR02169 794 P--EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL-------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1127 QLQAQRANVEAQEvallaererlmqdghrqRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLElerA 1206
Cdd:TIGR02169 865 ELEEELEELEAAL-----------------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK---A 924
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1207 QLEIQSQQLREsnqqLDLSACRLTTQCELLTQLRSAQEEENRqLLAEVQALSRENRelleRSLESRDHLHREQREYLDQL 1286
Cdd:TIGR02169 925 KLEALEEELSE----IEDPKGEDEEIPEEELSLEDVQAELQR-VEEEIRALEPVNM----LAIQEYEEVLKRLDELKEKR 995
|
410
....*....|....
gi 755563857 1287 NALRREKQKLVEKI 1300
Cdd:TIGR02169 996 AKLEEERKAILERI 1009
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
728-1167 |
1.16e-09 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 63.43 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 728 AIPEEQALRDEVAQLRRE----VAGLEVKLQAQAQRLearSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVD 803
Cdd:COG3096 247 AIRVTQSDRDLFKHLITEatnyVAADYMRHANERREL---SERALELRRELFGARRQLAEEQYRLVEMARELEELSARES 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 804 TASLELEAASRERealaealaaagrerrqwerdgprlrAQVEAAEQQVQALEsQVRCHLEEAEREHAEKQALREELEKAV 883
Cdd:COG3096 324 DLEQDYQAASDHL-------------------------NLVQTALRQQEKIE-RYQEDLEELTERLEEQEEVVEEAAEQL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 884 LRGQElgdRLEHLQEELEQAA---LERQKFLQEQENQHQRYRHLEQRLE--------AELQAASTSKEEAlmELKARALQ 952
Cdd:COG3096 378 AEAEA---RLEAAEEEVDSLKsqlADYQQALDVQQTRAIQYQQAVQALEkaralcglPDLTPENAEDYLA--AFRAKEQQ 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 953 LEEELIQLRQyPVDLATGARA----GPRTVETQNGrliEVERNNATLVA--------EKAALQGQLQHLEGQLGSLQGRA 1020
Cdd:COG3096 453 ATEEVLELEQ-KLSVADAARRqfekAYELVCKIAG---EVERSQAWQTArellrryrSQQALAQRLQQLRAQLAELEQRL 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1021 QelllQSQRAQEhssrlqaeksmmemQGQELHRKLGvleeEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGL 1100
Cdd:COG3096 529 R----QQQNAER--------------LLEEFCQRIG----QQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQ 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1101 LVRHRDLKANMRALELAHRELQGRHEQLQAQ--------------RANVEAQEVALLAERERLMQdghRQRGLEEELRRL 1166
Cdd:COG3096 587 LEQLRARIKELAARAPAWLAAQDALERLREQsgealadsqevtaaMQQLLEREREATVERDELAA---RKQALESQIERL 663
|
.
gi 755563857 1167 Q 1167
Cdd:COG3096 664 S 664
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
731-1308 |
1.54e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.16 E-value: 1.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEalcLSEELAQARRTEAEAHQEAEAQAR----EQARLREAVDTAS 806
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL---LEELNKKIKDLGEEEQLRVKEKIGeleaEIASLERSIAEKE 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 807 LELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRG 886
Cdd:TIGR02169 315 RELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 887 QELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEA------ELQAASTSKEEALMELKARALQLEEELIQL 960
Cdd:TIGR02169 395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEleeekeDKALEIKKQEWKLEQLAADLSKYEQELYDL 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 961 RQ-------------------------------YPVDLATGARAGPRTVETQNGRLIEVE-------------RNNATLV 996
Cdd:TIGR02169 475 KEeydrvekelsklqrelaeaeaqaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGeryataievaagnRLNNVVV 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 997 AEKAALQGQLQHLEGQLGslqGRAQELLLQSQRAQEHSSRLQAEKS---------------------------------- 1042
Cdd:TIGR02169 555 EDDAVAKEAIELLKRRKA---GRATFLPLNKMRDERRDLSILSEDGvigfavdlvefdpkyepafkyvfgdtlvvediea 631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1043 ---------MMEMQGqELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRA 1113
Cdd:TIGR02169 632 arrlmgkyrMVTLEG-ELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1114 LELAHR---ELQGRHEQLQAQranvEAQEVALLAERERLMQDGHRQR-GLEEELRRLQNEHERAQMLLAEVSRERGELqg 1189
Cdd:TIGR02169 711 LSDASRkigEIEKEIEQLEQE----EEKLKERLEELEEDLSSLEQEIeNVKSELKELEARIEELEEDLHKLEEALNDL-- 784
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1190 ERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRsaQEEENRQLLAEVQALSRENR-ELLERS 1268
Cdd:TIGR02169 785 EARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI--QELQEQRIDLKEQIKSIEKEiENLNGK 862
|
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 755563857 1269 LESrdhLHREQREYLDQLNALRREKQKLVEKIMD---QYRVLE 1308
Cdd:TIGR02169 863 KEE---LEEELEELEAALRDLESRLGDLKKERDEleaQLRELE 902
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
725-1266 |
1.93e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 62.83 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 725 LVSAIPEEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQarEQARLREaVDT 804
Cdd:pfam15921 115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLS--HEGVLQE-IRS 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 805 ASLELEAASREREALAEALAAA---------GRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEK--- 872
Cdd:pfam15921 192 ILVDFEEASGKKIYEHDSMSTMhfrslgsaiSKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRieq 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 873 ---------QALREELEKAVLRGQELGDRLEHLQE--------------ELEQAALERQKFLQEQENQHQ-RYRHLEQRL 928
Cdd:pfam15921 272 liseheveiTGLTEKASSARSQANSIQSQLEIIQEqarnqnsmymrqlsDLESTVSQLRSELREAKRMYEdKIEELEKQL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 929 ---EAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNG--------------RLIEVERN 991
Cdd:pfam15921 352 vlaNSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGnsitidhlrrelddRNMEVQRL 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 992 NATLVAEKAALQGQlqhLEGQLGSLQGRAQELllqsQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEE 1071
Cdd:pfam15921 432 EALLKAMKSECQGQ---MERQMAAIQGKNESL----EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1072 TRGQQQALLRDHEALVQLQRRQETELEgllvrhrdlkanmralELAHRELQGRHeqLQAQRANVEAQEVAlLAERERLMQ 1151
Cdd:pfam15921 505 LQEKERAIEATNAEITKLRSRVDLKLQ----------------ELQHLKNEGDH--LRNVQTECEALKLQ-MAEKDKVIE 565
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1152 DGHRQRgleEELRRLQNEHERAQmllAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTT 1231
Cdd:pfam15921 566 ILRQQI---ENMTQLVGQHGRTA---GAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVN 639
|
570 580 590
....*....|....*....|....*....|....*.
gi 755563857 1232 Q-CELLTQLRSAQEEENrQLLAEVQALSRENRELLE 1266
Cdd:pfam15921 640 AgSERLRAVKDIKQERD-QLLNEVKTSRNELNSLSE 674
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
752-1191 |
2.28e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.09 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 752 KLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASL--ELEAASREREALAE---ALAAA 826
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPErleELEER 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 827 GRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKqalREELEKAVlrgQELGDRLEHLQEELEQAALE 906
Cdd:COG4717 155 LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE---LEELQQRL---AELEEELEEAQEELEELEEE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 907 RQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLI 986
Cdd:COG4717 229 LEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 987 EVERNNATlvaEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRK-----LGVLEEE 1061
Cdd:COG4717 309 ALPALEEL---EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAallaeAGVEDEE 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1062 VRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHrDLKANMRALELAHRELQGRHEQLQAQRANVEaQEVA 1141
Cdd:COG4717 386 ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE-ELEEELEELEEELEELEEELEELREELAELE-AELE 463
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 755563857 1142 LLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGER 1191
Cdd:COG4717 464 QLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
733-1287 |
2.86e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 62.24 E-value: 2.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 733 QALRDEVAQLRREVAGLEVklQAQAQRLEARSAEALCLSEELAQARRteaeahQEAEAQAREQArLREAVDTASLELEAA 812
Cdd:COG4913 265 AAARERLAELEYLRAALRL--WFAQRRLELLEAELEELRAELARLEA------ELERLEARLDA-LREELDELEAQIRGN 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 813 SREREAL-AEALAAAGRERRQWERDGPRLRAQVEAAEQQV----QALESQVRCHLEEAEREHAEKQALREELEKAVLRGQ 887
Cdd:COG4913 336 GGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLpasaEEFAALRAEAAALLEALEEELEALEEALAEAEAALR 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 888 ELGDRLEHLQEELeqAALERQKFlqeqeNQHQRYRHLEQRLEAELQAastSKEEA-----LMELK--------------- 947
Cdd:COG4913 416 DLRRELRELEAEI--ASLERRKS-----NIPARLLALRDALAEALGL---DEAELpfvgeLIEVRpeeerwrgaiervlg 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 948 --ARALQLEEELIQ--------------LRQYPVDLATGARAGPRTVETQNGRLIEVERNNAT-----LVAEKAAL---- 1002
Cdd:COG4913 486 gfALTLLVPPEHYAaalrwvnrlhlrgrLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRawleaELGRRFDYvcvd 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1003 -QGQLQH------LEGQLgSLQGRAQELLLQSQRAQEH----SSRLQAEksmmemqgqELHRKLGVLEEEVRAARRAQEE 1071
Cdd:COG4913 566 sPEELRRhpraitRAGQV-KGNGTRHEKDDRRRIRSRYvlgfDNRAKLA---------ALEAELAELEEELAEAEERLEA 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1072 TRGQQQALLRDHEALVQLQRRQETEL--EGLLVRHRDLKANMRALELAHRELqgrhEQLQAQRANVEAQEVALLAERERL 1149
Cdd:COG4913 636 LEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLDASSDDL----AALEEQLEELEAELEELEEELDEL 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1150 MQdghRQRGLEEELRRLQNEHERAQMLLAEVsrERGELQGERGELRSRLARLELERAQLEIQsQQLRESNQQLDLSACRL 1229
Cdd:COG4913 712 KG---EIGRLEKELEQAEEELDELQDRLEAA--EDLARLELRALLEERFAAALGDAVERELR-ENLEERIDALRARLNRA 785
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 755563857 1230 TTQCE-LLTQLRSAQEEENRQLLAEVQALsRENRELLERsLEsRDHLHREQREYLDQLN 1287
Cdd:COG4913 786 EEELErAMRAFNREWPAETADLDADLESL-PEYLALLDR-LE-EDGLPEYEERFKELLN 841
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
839-1280 |
9.71e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 60.19 E-value: 9.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 839 RLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELekavlrgQELGDRLEHLQEELEQAALERQKFLQEQENQH 918
Cdd:pfam01576 226 ELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKI-------RELEAQISELQEDLESERAARNKAEKQRRDLG 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 919 QRYRHLEQRLEAEL------QAASTSKEEALMELKAralQLEEELiqlRQYPVDLATGARAGPRTVETQNGRLIEVERNN 992
Cdd:pfam01576 299 EELEALKTELEDTLdttaaqQELRSKREQEVTELKK---ALEEET---RSHEAQLQEMRQKHTQALEELTEQLEQAKRNK 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 993 ATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEET 1072
Cdd:pfam01576 373 ANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1073 RGQQQALLRDHEAL-VQLQRRQETeLEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQ----EVALLAERE 1147
Cdd:pfam01576 453 EGKNIKLSKDVSSLeSQLQDTQEL-LQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQlstlQAQLSDMKK 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1148 RLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSAC 1227
Cdd:pfam01576 532 KLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLA 611
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 755563857 1228 RLTTQCELLTQLRSAQEEENRQLLAEVQALSREnrelLERSLESRDHLHREQR 1280
Cdd:pfam01576 612 EEKAISARYAEERDRAEAEAREKETRALSLARA----LEEALEAKEELERTNK 660
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1028-1219 |
1.21e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 59.93 E-value: 1.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1028 QRAQEHSSRL-QAEKSMMEMQGQElhRKLGVLEEEVRAARRAQEETRGQQQALLR-DHEALVQLQRRQETELEGLLVRHR 1105
Cdd:COG4913 228 DALVEHFDDLeRAHEALEDAREQI--ELLEPIRELAERYAAARERLAELEYLRAAlRLWFAQRRLELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1106 DLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQR-----GLEEELRRL-----------QNE 1169
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERerrraRLEALLAALglplpasaeefAAL 385
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 755563857 1170 HERAQMLLAEVSRERGELQGERGELRSRLARLELERAQL--EIQSQQLRESN 1219
Cdd:COG4913 386 RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELeaEIASLERRKSN 437
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
630-1317 |
1.43e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.15 E-value: 1.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 630 SREAPQGELVHKAQVLKQESpkcRPRSAELTLREPLKDQKALDRELELSKQQKETGRHEQRPKGLESKLGPQKPQqtseg 709
Cdd:PTZ00121 1124 AEDARKAEEARKAEDARKAE---EARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRK----- 1195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 710 VPDAWSREEPTPGETLVSAipeEQALRDEVAQLRREVAGLEvklQAQAQRLEARSAEALCLSEEL-----AQARRTEAEA 784
Cdd:PTZ00121 1196 AEDARKAEAARKAEEERKA---EEARKAEDAKKAEAVKKAE---EAKKDAEEAKKAEEERNNEEIrkfeeARMAHFARRQ 1269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 785 HQEAEAQAREQARLREAVdtaslELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEE 864
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAE-----EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA 1344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 865 AEREHAEKQALREELEKAvlrgQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQ--RLEAELQAASTSKEEA 942
Cdd:PTZ00121 1345 AEAAKAEAEAAADEAEAA----EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkKKADELKKAAAAKKKA 1420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 943 lMELKARALQLE--EELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRA 1020
Cdd:PTZ00121 1421 -DEAKKKAEEKKkaDEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1021 QEL--LLQSQRAQEHSSRLQAEKSMMEMQGQELHRKlgvlEEEVRAA--RRAQEETRGQQQALLRDHEALVQLQRRQETE 1096
Cdd:PTZ00121 1500 DEAkkAAEAKKKADEAKKAEEAKKADEAKKAEEAKK----ADEAKKAeeKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1097 LEGLLVRHRDLKANMRA-----LELAHRELQGRHEQL-QAQRANVEAQEVAllAERERLMQDGHRQRGLEEELRR---LQ 1167
Cdd:PTZ00121 1576 KNMALRKAEEAKKAEEArieevMKLYEEEKKMKAEEAkKAEEAKIKAEELK--KAEEEKKKVEQLKKKEAEEKKKaeeLK 1653
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1168 NEHERAQMLLAEVSRERGELQGERGELRsrlaRLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAqEEEN 1247
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAK----KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA-EEEN 1728
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755563857 1248 RQLLAEVQALSRENR---ELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLEPGPLPRTKK 1317
Cdd:PTZ00121 1729 KIKAEEAKKEAEEDKkkaEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1058-1272 |
2.15e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 2.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1058 LEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEA 1137
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1138 QevalLAERERLMQDGHRQRGLEEELRRLQ-NEHERAQMLLAEVSRER----GELQGERGELRSRLARLELERAQLEIQS 1212
Cdd:COG4942 105 E----LAELLRALYRLGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARreqaEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1213 QQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESR 1272
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
195-489 |
3.08e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 3.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 195 GPESGELVAEELEMQLRSLTGMMSRLARERDLGAQRLAELLLEREPAHLLLpeapanASAEGVSHHLALQLTNAKAQLRR 274
Cdd:TIGR02168 664 GSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL------EQLRKELEELSRQISALRKDLAR 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 275 LRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERA--------GRLPRLQEELRRCRE 346
Cdd:TIGR02168 738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkalrEALDELRAELTLLNE 817
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 347 KLQAAEVFKGQLEEERvlsEALEASKVLLEEQLEVARERSARLHETQREnllLRTRLGEAHADLDSLRHQLEQLVEenve 426
Cdd:TIGR02168 818 EAANLRERLESLERRI---AATERRLEDLEEQIEELSEDIESLAAEIEE---LEELIEELESELEALLNERASLEE---- 887
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755563857 427 lelelqrslepppgspgeaslpgAAPSLQDEVREAEAgRLRAVERENRELRGQLQMLQAQLGS 489
Cdd:TIGR02168 888 -----------------------ALALLRSELEELSE-ELRELESKRSELRRELEELREKLAQ 926
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
276-990 |
3.86e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 58.61 E-value: 3.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 276 RQEVEEKAEQLLDSQAEVQGLEaEIRR---LRQETQALSAQ-AKRAELYREEAEAlreRAGRLPRLQEELRRCREKLQAA 351
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAEDARKAE-EARKaedARKAEEARKAEdAKRVEIARKAEDA---RKAEEARKAEDAKKAEAARKAE 1185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 352 EVFKGqlEEERVLSEALEASKVLLEEqlEVARERSARLHETQRENLLLRtRLGEAHADLDSLRHQLEQLVEENVELELEL 431
Cdd:PTZ00121 1186 EVRKA--EELRKAEDARKAEAARKAE--EERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 432 QRSLEPPPGSPGEASLPGAApslqDEVREAEAGRLRAVERENRELRgqlQMLQAQLGSQHPLLEEQRENSRQPPVPNRDP 511
Cdd:PTZ00121 1261 RMAHFARRQAAIKAEEARKA----DELKKAEEKKKADEAKKAEEKK---KADEAKKKAEEAKKADEAKKKAEEAKKKADA 1333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 512 ATPSALHHSPQSPACQigGEGSESLDLPSPASYSDITRSPKCSQAPDSHPELESPLQMVSQDPQTSDQALQESDPTVETH 591
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAK--AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELK 1411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 592 QCLEKSGHRVPLQSpivwdppQGPEVRiEVQELlgETGSREAPQGELVHKAQVLKQESPKCRPRSAELTLREPLKDQKAL 671
Cdd:PTZ00121 1412 KAAAAKKKADEAKK-------KAEEKK-KADEA--KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 672 DRELELSKQQKETGRH--EQRPKGLESKLGPQKPQQTSEG--VPDAWSREEPTPGETLVSAipEEQALRDEVAQLRREVA 747
Cdd:PTZ00121 1482 AKKADEAKKKAEEAKKkaDEAKKAAEAKKKADEAKKAEEAkkADEAKKAEEAKKADEAKKA--EEKKKADELKKAEELKK 1559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 748 GLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAR----EQARLREAVDTASLELEAASRerealaeal 823
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKkmkaEEAKKAEEAKIKAEELKKAEE--------- 1630
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 824 aaagrERRQWERDGPRLRAQVEAAEQqVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQA 903
Cdd:PTZ00121 1631 -----EKKKVEQLKKKEAEEKKKAEE-LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA 1704
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 904 ALERQKFLQEQENQHQRYRHLEQRleaELQAASTSKEEALMELKARALQLEEE----LIQLRQYPVDLATGARAGPRTV- 978
Cdd:PTZ00121 1705 EELKKKEAEEKKKAEELKKAEEEN---KIKAEEAKKEAEEDKKKAEEAKKDEEekkkIAHLKKEEEKKAEEIRKEKEAVi 1781
|
730
....*....|....*..
gi 755563857 979 -----ETQNGRLIEVER 990
Cdd:PTZ00121 1782 eeeldEEDEKRRMEVDK 1798
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
828-1210 |
4.20e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.21 E-value: 4.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDG------PRLRAQVEAAEQQVQALESQVRCHLEEA----EREHAEKQALREELEKAVLRGQELGDRLEHLQ 897
Cdd:pfam15921 399 QNKRLWDRDTgnsitiDHLRRELDDRNMEVQRLEALLKAMKSECqgqmERQMAAIQGKNESLEKVSSLTAQLESTKEMLR 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 898 EELEQAALERQKFLQEQENQHQRYRHLEQRLEA-ELQAASTSKEEALMELKARALQ-LEEELIQLRQYPVDLAtgaraGP 975
Cdd:pfam15921 479 KVVEELTAKKMTLESSERTVSDLTASLQEKERAiEATNAEITKLRSRVDLKLQELQhLKNEGDHLRNVQTECE-----AL 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 976 RTVETQNGRLIEVER----NNATLVAEKAALQGQLQ----HLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQ 1047
Cdd:pfam15921 554 KLQMAEKDKVIEILRqqieNMTQLVGQHGRTAGAMQvekaQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELE 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1048 GQELhrkLGVLEEEVRAARRAQEE----------TRGQQQALLRDHEALVQLQRRQETELEGLLVRHR-DLKANMRALEL 1116
Cdd:pfam15921 634 KVKL---VNAGSERLRAVKDIKQErdqllnevktSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQSELEQ 710
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1117 AHRELQ--------------GRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEheraqmlLAEVSR 1182
Cdd:pfam15921 711 TRNTLKsmegsdghamkvamGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQE-------LSTVAT 783
|
410 420
....*....|....*....|....*...
gi 755563857 1183 ERGELQGERGELRSRLARLELERAQLEI 1210
Cdd:pfam15921 784 EKNKMAGELEVLRSQERRLKEKVANMEV 811
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
655-1300 |
5.60e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 57.67 E-value: 5.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 655 RSAELTLREPLKDQKALDRELELSKQQKETGRHEQRPKGLESKLgpQKPQQTSEGVPDAWSREEPTPGETLVSAIPEEQA 734
Cdd:TIGR00618 153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKA--ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKH 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 735 LRDEVAQLRREVAGLEVKLQAQAQRLEarsaealcLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAASR 814
Cdd:TIGR00618 231 LREALQQTQQSHAYLTQKREAQEEQLK--------KQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAV 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 815 EREALAEALAAAGRERRQWERDGPRLR----AQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELG 890
Cdd:TIGR00618 303 TQIEQQAQRIHTELQSKMRSRAKLLMKraahVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIH 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAALERQKFLQEQENQHQR-YRHLEQR-LEAELQAASTSKEEALMELKARALQLEEELIQLRQ---YPV 965
Cdd:TIGR00618 383 TLQQQKTTLTQKLQSLCKELDILQREQATIdTRTSAFRdLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLekiHLQ 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 966 DLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQS------QRAQEHSSRLQA 1039
Cdd:TIGR00618 463 ESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGpltrrmQRGEQTYAQLET 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1040 EKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLvRHRDLKANMRALELAHR 1119
Cdd:TIGR00618 543 SEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLS-EAEDMLACEQHALLRKL 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1120 ELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLA 1199
Cdd:TIGR00618 622 QPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQ 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1200 RLELERAQLEIQSQQLRESNQQLDLSACR---LTTQCELLTQ-LRSAQEEENRQLLAEVQALSRENRELL--ERSLESRD 1273
Cdd:TIGR00618 702 CQTLLRELETHIEEYDREFNEIENASSSLgsdLAAREDALNQsLKELMHQARTVLKARTEAHFNNNEEVTaaLQTGAELS 781
|
650 660
....*....|....*....|....*..
gi 755563857 1274 HLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:TIGR00618 782 HLAAEIQFFNRLREEDTHLLKTLEAEI 808
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
867-1300 |
7.72e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 57.49 E-value: 7.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 867 REHAEKQALREELEKAvlrgQELGDRLEHLQEELEQaaleRQKFLQEQENQHQRYRHLEQRLEAElqaastsKEEALMEL 946
Cdd:pfam01576 2 RQEEEMQAKEEELQKV----KERQQKAESELKELEK----KHQQLCEEKNALQEQLQAETELCAE-------AEEMRARL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 947 KARALQLEEELIQLRqypvdlatgaragprtvetqnGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQ 1026
Cdd:pfam01576 67 AARKQELEEILHELE---------------------SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLE 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1027 SQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEE---EVRAARRAQEETRGQQQALLRDHEALV-QLQRRQETELEGllv 1102
Cdd:pfam01576 126 KVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEErisEFTSNLAEEEEKAKSLSKLKNKHEAMIsDLEERLKKEEKG--- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1103 rHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQ----EVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQmllA 1178
Cdd:pfam01576 203 -RQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQlakkEEELQAALARLEEETAQKNNALKKIRELEAQISELQ---E 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1179 EVSRERGelQGERGELRSRLARLELERAQLEIQSqQLRESNQQLDLSACRLTTqcelLTQLRSAQEEENRQLLAEVQALS 1258
Cdd:pfam01576 279 DLESERA--ARNKAEKQRRDLGEELEALKTELED-TLDTTAAQQELRSKREQE----VTELKKALEEETRSHEAQLQEMR 351
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 755563857 1259 RENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:pfam01576 352 QKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAEL 393
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
967-1226 |
7.74e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 7.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 967 LATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEM 1046
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1047 QGQELHRKLGVLEEEVRaarraqeetrgqqqallrdhEALVQLQRRQETELEGLLVRHRDLKANMRALELAH---RELQG 1123
Cdd:COG4942 91 EIAELRAELEAQKEELA--------------------ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKylaPARRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1124 RHEQLQAQRANVEAQEVALLAERERLMQDghrQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLEL 1203
Cdd:COG4942 151 QAEELRADLAELAALRAELEAERAELEAL---LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
250 260
....*....|....*....|...
gi 755563857 1204 ERAQLEIQSQQLRESNQQLDLSA 1226
Cdd:COG4942 228 LIARLEAEAAAAAERTPAAGFAA 250
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
844-1273 |
1.25e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 56.65 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 844 VEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQ---R 920
Cdd:pfam05483 263 LEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEelnK 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 921 YRHLEQRLEAELQAASTSKEEALMELKARalqLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNaTLVAEKA 1000
Cdd:pfam05483 343 AKAAHSFVVTEFEATTCSLEELLRTEQQR---LEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELK-KILAEDE 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1001 ALQGQLQHLEGQLGSLQGRAQEL--LLQSQRAQEHSsrLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQA 1078
Cdd:pfam05483 419 KLLDEKKQFEKIAEELKGKEQELifLLQAREKEIHD--LEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDK 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1079 LLRDHEALVQ--------LQRRQETELEGLLVRHRDLKA--NMRALELAHR-ELQGRHEQLQAQRANV-----EAQEVAL 1142
Cdd:pfam05483 497 LLLENKELTQeasdmtleLKKHQEDIINCKKQEERMLKQieNLEEKEMNLRdELESVREEFIQKGDEVkckldKSEENAR 576
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1143 LAERERLMQDgHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQ----GERGELRS---RLARLELERA--------- 1206
Cdd:pfam05483 577 SIEYEVLKKE-KQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsAENKQLNAyeiKVNKLELELAsakqkfeei 655
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755563857 1207 ----QLEIQSQQLRESNQQLDLSACRLTTqcELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRD 1273
Cdd:pfam05483 656 idnyQKEIEDKKISEEKLLEEVEKAKAIA--DEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERD 724
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
840-1224 |
1.33e-07 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 56.06 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 840 LRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVlrgQELGDRLEHLQEELEQAALERQKFLQEQENqhq 919
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQR---RELESRVAELKEELRQSREKHEELEEKYKE--- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 920 ryrhlEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVErnnatlvAEK 999
Cdd:pfam07888 106 -----LSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEE-------AER 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1000 AALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQ-- 1077
Cdd:pfam07888 174 KQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERkv 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1078 -ALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQ-LQAQRANVEAqevallaERERLMQDGHR 1155
Cdd:pfam07888 254 eGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQeRETLQQSAEA-------DKDRIEKLSAE 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755563857 1156 QRGLEEelrRLQNEHERAQMLLAEVSRER-------GELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDL 1224
Cdd:pfam07888 327 LQRLEE---RLQEERMEREKLEVELGREKdcnrvqlSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQ 399
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1090-1308 |
1.40e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.60 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1090 QRRQETELegllvRHRDLKANMRALELAHRELQGRHEQLQAQ----------RANVEAQEVALLA--------ERERLMQ 1151
Cdd:TIGR02168 172 ERRKETER-----KLERTRENLDRLEDILNELERQLKSLERQaekaerykelKAELRELELALLVlrleelreELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1152 D----GHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSAC 1227
Cdd:TIGR02168 247 ElkeaEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1228 RLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLhREQREYLDQLNALRREKQKLVEKIMDQYRVL 1307
Cdd:TIGR02168 327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-EELEEQLETLRSKVAQLELQIASLNNEIERL 405
|
.
gi 755563857 1308 E 1308
Cdd:TIGR02168 406 E 406
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
134-475 |
1.46e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.48 E-value: 1.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 134 EEAVDELESILRLLLGASVQCEHRELFIRHIRGLSLDVQSELAGAIQEVTQPGAGVVLALAGPESGELVAEELEMQLRSL 213
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 214 TGMMSRLARERDLGAQRLAELLLEREpahlllpeapanasaegvshHLALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEV 293
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELE--------------------EAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 294 QGLEAEIRRLRQETQALSAQAKRA--ELYREEAEALRERAgrlprlqEELRRCREKLQAAEVFKGQLEEERVLSEALEAS 371
Cdd:COG1196 389 LEALRAAAELAAQLEELEEAEEALleRLERLEEELEELEE-------ALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 372 KVLLEEQLEVARERSARLHETQRENLLLRTRLgeahadldSLRHQLEQLVEENVELELELQRSLEPPPGSPGEASLPGAA 451
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARL--------LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533
|
330 340
....*....|....*....|....
gi 755563857 452 PSLQDEVREAEAGRLRAVERENRE 475
Cdd:COG1196 534 AAYEAALEAALAAALQNIVVEDDE 557
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
733-1267 |
2.64e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 55.68 E-value: 2.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 733 QALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAA 812
Cdd:PRK01156 193 KSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKN 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 813 ---SREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHlEEAEREHAEKQALREELEKAvlrgQEL 889
Cdd:PRK01156 273 nyyKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKY-HAIIKKLSVLQKDYNDYIKK----KSR 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 890 GDRLEHLQEELEQAALERQKFLQEQENQHQRYRhlEQRLEAELQAASTSKEEALMELKARALQLEEELIqlrqypvdlat 969
Cdd:PRK01156 348 YDDLNNQILELEGYEMDYNSYLKSIESLKKKIE--EYSKNIERMSAFISEILKIQEIDPDAIKKELNEI----------- 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 970 garagprtvetqNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRL----QAEKSMME 1045
Cdd:PRK01156 415 ------------NVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIinhyNEKKSRLE 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1046 MQGQELHRKLGVLEEEVRAARRAQEETRGQQ-------QALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAH 1118
Cdd:PRK01156 483 EKIREIEIEVKDIDEKIVDLKKRKEYLESEEinksineYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLED 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1119 RE--------------------LQGRHEQLQAQRANVEA--QEVALLAERERLMQDGHRQRgLEEELRRLQNEHERAQml 1176
Cdd:PRK01156 563 LDskrtswlnalavislidietNRSRSNEIKKQLNDLESrlQEIEIGFPDDKSYIDKSIRE-IENEANNLNNKYNEIQ-- 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1177 laEVSRERGELQGERGELRSRLARL-ELERAQLEIQSqQLRESNQQLDLSACRLTTQCELLTQLRSaQEEENRQLLAEVQ 1255
Cdd:PRK01156 640 --ENKILIEKLRGKIDNYKKQIAEIdSIIPDLKEITS-RINDIEDNLKKSRKALDDAKANRARLES-TIEILRTRINELS 715
|
570
....*....|..
gi 755563857 1256 ALSRENRELLER 1267
Cdd:PRK01156 716 DRINDINETLES 727
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
203-499 |
3.29e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.33 E-value: 3.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 203 AEELEMQLRSLTGMMSRLARERDLGAQRLAELLLEREPAHLLLpeapanASAEGVSHHLALQLTNAKAQLRRLRQEVEEK 282
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAEL------EELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 283 AEQLLDSQAEVQGLEAEIRRLRQETQAL-----SAQAKRAELYREEAEALRERAGRLPRLQEELRRCREKLQAAEVFKGQ 357
Cdd:COG1196 301 EQDIARLEERRRELEERLEELEEELAELeeeleELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 358 LEEERVLSEALEASKVLLEEQLEVARERSARLHETQRENLLLRTRLGEAHADLDSLRHQLEQLVEENVELELELQRSLEp 437
Cdd:COG1196 381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE- 459
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755563857 438 ppgspgeaslpGAAPSLQDEVREAEAGR--LRAVERENRELRGQLQMLQAQLGSQHPLLEEQRE 499
Cdd:COG1196 460 -----------ALLELLAELLEEAALLEaaLAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
267-436 |
3.38e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 3.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 267 NAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQAL--------------SAQAKRAELyREEAEALRERAG 332
Cdd:COG4913 607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALqrlaeyswdeidvaSAEREIAEL-EAELERLDASSD 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 333 RLPRLQEELRRCREKLQAAEVFKGQLEEERvlsEALEASKVLLEEQLEVARERSARLHETQRE--NLLLRTRLGEAHAD- 409
Cdd:COG4913 686 DLAALEEQLEELEAELEELEEELDELKGEI---GRLEKELEQAEEELDELQDRLEAAEDLARLelRALLEERFAAALGDa 762
|
170 180
....*....|....*....|....*...
gi 755563857 410 -LDSLRHQLEQLVEENVELELELQRSLE 436
Cdd:COG4913 763 vERELRENLEERIDALRARLNRAEEELE 790
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
845-1296 |
4.49e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.98 E-value: 4.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 845 EAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHL 924
Cdd:pfam02463 161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 925 EQRLEAELQAASTSKEEALMELKARALQLEEELIQLrqypvdlatgaragprtvETQNGRLIEVERnnATLVAEKAALQG 1004
Cdd:pfam02463 241 LLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE------------------EEKEKKLQEEEL--KLLAKEEEELKS 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1005 QLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDH- 1083
Cdd:pfam02463 301 ELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKk 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1084 EALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRglEEEL 1163
Cdd:pfam02463 381 LESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELE--KQEL 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1164 RRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQ 1243
Cdd:pfam02463 459 KLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV 538
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 755563857 1244 EEENRQLLAEVQALsrenRELLERSLESRDHLHREQREYLDQLNALRREKQKL 1296
Cdd:pfam02463 539 ENYKVAISTAVIVE----VSATADEVEERQKLVRALTELPLGARKLRLLIPKL 587
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1141 |
4.96e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 4.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 917 QHQRYRHLEQRLEaELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLAtgaragpRTVETQNGRLIEVERNNATLV 996
Cdd:COG4942 18 QADAAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA-------RRIRALEQELAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 997 AEKAALQGQLQHLEGQLGSLQGRAQ--------ELLLQSQRAQEHSSRLQAEKSMMEM---QGQELHRKLGVLEEEVRAA 1065
Cdd:COG4942 90 KEIAELRAELEAQKEELAELLRALYrlgrqpplALLLSPEDFLDAVRRLQYLKYLAPArreQAEELRADLAELAALRAEL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755563857 1066 RRAQEETRGQQQALLRDHEALVQLQRRQETELegllvrhRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVA 1141
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKAERQKLL-------ARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1143-1300 |
9.33e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.62 E-value: 9.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1143 LAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLEL--ERAQLEIQSQQLRESNQ 1220
Cdd:COG4717 70 LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPERLE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1221 QLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:COG4717 150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
264-432 |
1.10e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.23 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 264 QLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAG---RLPRLQEE 340
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAElpeRLEELEER 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 341 LRRCREKLQAAEVFKGQLEE-ERVLSEALEASKVLLEEQLEVARERSARLHETQREnllLRTRLGEAHADLDSLRHQLEQ 419
Cdd:COG4717 155 LEELRELEEELEELEAELAElQEELEELLEQLSLATEEELQDLAEELEELQQRLAE---LEEELEEAQEELEELEEELEQ 231
|
170
....*....|...
gi 755563857 420 LVEENVELELELQ 432
Cdd:COG4717 232 LENELEAAALEER 244
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
873-1305 |
1.62e-06 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 52.88 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 873 QALREELEKavLRGQELGDRL------EHLQEELEQAALERQKFLQEQENQHQRYRHLEQR--LEAELQAASTSKEEALM 944
Cdd:PRK10246 194 KSARTELEK--LQAQASGVALltpeqvQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLdeLQQEASRRQQALQQALA 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 945 ELKARA-----LQLEEELIQLR---QYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSL 1016
Cdd:PRK10246 272 AEEKAQpqlaaLSLAQPARQLRphwERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTW 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1017 QGRAQELLLQSQ-----RAQ-EHSSRLQAEKSMMEMQGQELHRKLGVL--------EEEVRAARRAQEETRGQQQALLRD 1082
Cdd:PRK10246 352 LAEHDRFRQWNNelagwRAQfSQQTSDREQLRQWQQQLTHAEQKLNALpaitltltADEVAAALAQHAEQRPLRQRLVAL 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1083 HEALVQLQRRQETelegllvrhrdlkaNMRALELAHRELQGRHEQLQAQR-----ANVEAQEVALLAERERLMQDghrqr 1157
Cdd:PRK10246 432 HGQIVPQQKRLAQ--------------LQVAIQNVTQEQTQRNAALNEMRqrykeKTQQLADVKTICEQEARIKD----- 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1158 gLEEELRRLQ----------NEH---ERAQMLlaevsrergelqgERGELRSRLARLELERAQLEIQSQQLResnqqldl 1224
Cdd:PRK10246 493 -LEAQRAQLQagqpcplcgsTSHpavEAYQAL-------------EPGVNQSRLDALEKEVKKLGEEGAALR-------- 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1225 sacrltTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLER---SLESRDHLH---REQREYLDQLNALrREKQKLVE 1298
Cdd:PRK10246 551 ------GQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASlniTLQPQDDIQpwlDAQEEHERQLRLL-SQRHELQG 623
|
....*..
gi 755563857 1299 KIMDQYR 1305
Cdd:PRK10246 624 QIAAHNQ 630
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
891-1145 |
1.70e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 1.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAAlERQKFLQEQENQHQRYRHLEQRLeAELQAastskeealMELKARALQLEEELIQLRQypvdlatg 970
Cdd:COG4913 235 DDLERAHEALEDAR-EQIELLEPIRELAERYAAARERL-AELEY---------LRAALRLWFAQRRLELLEA-------- 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 971 aragprtvetqngrliEVERNNAtlvaEKAALQGQLQHLEGQLGSLQGRAQELllQSQRAQEHSSRLQAEKSMMEMQGQE 1050
Cdd:COG4913 296 ----------------ELEELRA----ELARLEAELERLEARLDALREELDEL--EAQIRGNGGDRLEQLEREIERLERE 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1051 LHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQA 1130
Cdd:COG4913 354 LEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
|
250
....*....|....*
gi 755563857 1131 QRANVEAQEVALLAE 1145
Cdd:COG4913 434 RKSNIPARLLALRDA 448
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
731-1223 |
1.83e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.05 E-value: 1.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELaQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:TIGR00618 373 QQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRT-SAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERRQWERDGPRLRAQVE---AAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQ 887
Cdd:TIGR00618 452 QCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETrkkAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 888 ELGDRLEHLQEELEQAALErqkfLQEQENQHQRYRHLEQRLEAELQAAsTSKEEALMELKARALQLEEELIQLRQypvdl 967
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHQ----LTSERKQRASLKEQMQEIQQSFSIL-TQCDNRSKEDIPNLQNITVRLQDLTE----- 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 968 atgARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQ-LGSLQGRAQELLLQSQRAQEHSSRLQAEKSmmem 1046
Cdd:TIGR00618 602 ---KLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALkLTALHALQLTLTQERVREHALSIRVLPKEL---- 674
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1047 qGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQG-RH 1125
Cdd:TIGR00618 675 -LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHqAR 753
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1126 EQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGE-----------LQGERGEL 1194
Cdd:TIGR00618 754 TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSdedilnlqcetLVQEEEQF 833
|
490 500
....*....|....*....|....*....
gi 755563857 1195 RSRLARLELERAQLEIQSQQLRESNQQLD 1223
Cdd:TIGR00618 834 LSRLEEKSATLGEITHQLLKYEECSKQLA 862
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
737-1208 |
2.26e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 52.65 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 737 DEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELA------QARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:PRK04863 286 EEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESdleqdyQAASDHLNLVQTALRQQEKIERYQADLEELEERLE 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASRErealaealaaagRERRQWERDgpRLRAQVEAAEQQVQALESQ---VRCHLEEAERE----HAEKQALREE---LE 880
Cdd:PRK04863 366 EQNEV------------VEEADEQQE--ENEARAEAAEEEVDELKSQladYQQALDVQQTRaiqyQQAVQALERAkqlCG 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 881 KAVLRGQELGDRLEHLQEELEQAALERqkflqeqenqhqryRHLEQRLEAElQAASTSKEEAlMELKARAlqleeeliql 960
Cdd:PRK04863 432 LPDLTADNAEDWLEEFQAKEQEATEEL--------------LSLEQKLSVA-QAAHSQFEQA-YQLVRKI---------- 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 961 rqypvdlatgarAGprtvetqngrliEVERNNAtlvaekaalqgqlqhlegqlgslQGRAQELLLQSQRAQEHSSRLQAe 1040
Cdd:PRK04863 486 ------------AG------------EVSRSEA-----------------------WDVARELLRRLREQRHLAEQLQQ- 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1041 ksmMEMQGQELHRKLgvleEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLlvrhRDLKANMRALELAHRE 1120
Cdd:PRK04863 518 ---LRMRLSELEQRL----RQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESL----SESVSEARERRMALRQ 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1121 LQgrhEQLQAQRANVEAQEVALLAERERLMQDGhRQRGLEEELRRlQNEHERAQMLLaevsRERgELQGERGELRSRLAR 1200
Cdd:PRK04863 587 QL---EQLQARIQRLAARAPAWLAAQDALARLR-EQSGEEFEDSQ-DVTEYMQQLLE----RER-ELTVERDELAARKQA 656
|
....*...
gi 755563857 1201 LELERAQL 1208
Cdd:PRK04863 657 LDEEIERL 664
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
924-1188 |
2.31e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 52.33 E-value: 2.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 924 LEQRLEAELQAASTSK---EEALMELKARALQLEEELIQLRQypvdlatgaragprtvetQNGrLIEVERNNATLVAEKA 1000
Cdd:COG3206 162 LEQNLELRREEARKALeflEEQLPELRKELEEAEAALEEFRQ------------------KNG-LVDLSEEAKLLLQQLS 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1001 ALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMmemqgQELHRKLGVLEeevraARRAQEETRgqqqaLL 1080
Cdd:COG3206 223 ELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVI-----QQLRAQLAELE-----AELAELSAR-----YT 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1081 RDHEALVQLQRRQEtelegllvrhrDLKANMRalelahRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLE 1160
Cdd:COG3206 288 PNHPDVIALRAQIA-----------ALRAQLQ------QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE 350
|
250 260
....*....|....*....|....*...
gi 755563857 1161 EELRRLQNEHERAQMLLAEVSRERGELQ 1188
Cdd:COG3206 351 AELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
855-1289 |
2.70e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 52.27 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 855 ESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQE---ELE---QAALERQKFLQE---QENQHQRYR--- 922
Cdd:PRK04863 278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEaesDLEqdyQAASDHLNLVQTalrQQEKIERYQadl 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 923 -HLEQRLEAELQAASTSKEEaLMELKARALQLEEELIQLRqypvdlatgaragprtvetqnGRLIEVERnnATLVAEKAA 1001
Cdd:PRK04863 358 eELEERLEEQNEVVEEADEQ-QEENEARAEAAEEEVDELK---------------------SQLADYQQ--ALDVQQTRA 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1002 LQGQ--LQHLEgqlgslqgRAQELLLQSQRAQEHSSRLQAEksmMEMQGQELHRKLGVLEEEVRAArraqeetrgqqQAL 1079
Cdd:PRK04863 414 IQYQqaVQALE--------RAKQLCGLPDLTADNAEDWLEE---FQAKEQEATEELLSLEQKLSVA-----------QAA 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1080 LRDHEALVQLQRRQETELEgllvrhrdlkaNMRALELAhRELQGRHEQLQAQRANVEAQEVALlaerERLMQDGHRQRGL 1159
Cdd:PRK04863 472 HSQFEQAYQLVRKIAGEVS-----------RSEAWDVA-RELLRRLREQRHLAEQLQQLRMRL----SELEQRLRQQQRA 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1160 EEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQL 1239
Cdd:PRK04863 536 ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARL 615
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 755563857 1240 R--SAQEEENRQLLAE-VQALSRENRELlersLESRDHLHREQREYLDQLNAL 1289
Cdd:PRK04863 616 ReqSGEEFEDSQDVTEyMQQLLEREREL----TVERDELAARKQALDEEIERL 664
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
262-419 |
2.72e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 262 ALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEA--EALRERAGRLPRLQE 339
Cdd:COG4913 273 ELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNggDRLEQLEREIERLER 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 340 ELRRCREKLQAAEVFKGQLEEERVLSEA-LEASKVLLEEQLEVARERSARLHETQRENLLLRTRLGEAHADLDSLRHQLE 418
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEeFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
|
.
gi 755563857 419 Q 419
Cdd:COG4913 433 R 433
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
60-182 |
3.07e-06 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 48.56 E-value: 3.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 60 LIDGALLLRVLGIIAPSSRGGLRMVRGRDGPAA---CRMWNLCHLWGRLRDFYQEELQLLILSPP-PDLQTMG--CDPfs 133
Cdd:pfam19047 25 LTDGVAMAQVLHQIDPSWFTEAWLSRIKEDVGDnwrLKVSNLKKILQSVVDYYQDVLGQQISDFLlPDVNLIGehSDP-- 102
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 755563857 134 eeavDELESILRLLLGASVQCEHRELFIRHIRGLSLDVQSELAGAIQEV 182
Cdd:pfam19047 103 ----AELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
730-1209 |
3.17e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.99 E-value: 3.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 730 PEEQALRDEVAQLRREVAGLE---VKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREavdtas 806
Cdd:PRK03918 214 SELPELREELEKLEKEVKELEelkEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE------ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 807 leLEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRcHLEEAEREHAEKQALREELEKAVLRG 886
Cdd:PRK03918 288 --LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE-RLEELKKKLKELEKRLEELEERHELY 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 887 QELGDRLEHLQE-ELEQAALERQKFLQEQENQHQRYRHLEQRLE------AELQAASTSKEEALMELKA---------RA 950
Cdd:PRK03918 365 EEAKAKKEELERlKKRLTGLTPEKLEKELEELEKAKEEIEEEISkitariGELKKEIKELKKAIEELKKakgkcpvcgRE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 951 LQLEEELIQLRQYPVDLA----TGARAGPRTVETQNgRLIEVER---NNATLVAEKAALQgQLQHLEGQLGS-----LQG 1018
Cdd:PRK03918 445 LTEEHRKELLEEYTAELKriekELKEIEEKERKLRK-ELRELEKvlkKESELIKLKELAE-QLKELEEKLKKynleeLEK 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1019 RAQELLLQSQRAQEHSSRLQAEKSMMEmQGQELHRKLGVLEEEVRAARRAQEETRGQQQALlrDHEALVQLQRRQEtELE 1098
Cdd:PRK03918 523 KAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAELLKELEEL--GFESVEELEERLK-ELE 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1099 GLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLmqDGHRQRGLEEELRRLQNEHERAQMLLA 1178
Cdd:PRK03918 599 PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL--EELEKKYSEEEYEELREEYLELSRELA 676
|
490 500 510
....*....|....*....|....*....|.
gi 755563857 1179 EVSRERGELQGERGELRSRLARLELERAQLE 1209
Cdd:PRK03918 677 GLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
724-1292 |
4.15e-06 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 51.80 E-value: 4.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 724 TLVSAIPEEQALRDEVAQLRREVAGLEVKLQAQAQ--------RLEARSAEALCLSEEL---AQARRTEAEAHQEAEAQA 792
Cdd:COG3321 805 GLVRQCLAAAGDAVVLPSLRRGEDELAQLLTALAQlwvagvpvDWSALYPGRGRRRVPLptyPFQREDAAAALLAAALAA 884
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 793 REQARLREAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEK 872
Cdd:COG3321 885 ALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEAGAL 964
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 873 QALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQ 952
Cdd:COG3321 965 LLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAA 1044
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 953 LEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQE 1032
Cdd:COG3321 1045 AAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALLLLALLAALALAAAAAAL 1124
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1033 HSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMR 1112
Cdd:COG3321 1125 LALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALLLAALLAAL 1204
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1113 ALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERG 1192
Cdd:COG3321 1205 LAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALAALALLAAAAGLAALAAAAAAAAAA 1284
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1193 ELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESR 1272
Cdd:COG3321 1285 LALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAAAAAAALA 1364
|
570 580
....*....|....*....|
gi 755563857 1273 DHLHREQREYLDQLNALRRE 1292
Cdd:COG3321 1365 AAAGAAAAAAALALAALAAA 1384
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
907-1271 |
4.36e-06 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 50.83 E-value: 4.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 907 RQKFLQEQENQHQRYRHLEQRLeaelQAASTSKEEAL-------MELKARALQLEEELIQLRQypvdlatgaragprTVE 979
Cdd:pfam15742 4 GEKLKYQQQEEVQQLRQNLQRL----QILCTSAEKELryergknLDLKQHNSLLQEENIKIKA--------------ELK 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 980 TQNGRLIEVERNNATLVAEKAALQGQLQHLEGQ-LGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQgQELHRKLGVL 1058
Cdd:pfam15742 66 QAQQKLLDSTKMCSSLTAEWKHCQQKIRELELEvLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQ-QKLEHAHKVC 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1059 EEEVRAARRAQEETRGQQ----QALLRDHEALVQLQRRQ-ETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRA 1133
Cdd:pfam15742 145 LTDTCILEKKQLEERIKEasenEAKLKQQYQEEQQKRKLlDQNVNELQQQVRSLQDKEAQLEMTNSQQQLRIQQQEAQLK 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1134 NVEAqevallaerERLMQDGHR--QRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRL-ARLELERAQLEI 1210
Cdd:pfam15742 225 QLEN---------EKRKSDEHLksNQELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHkAKLRRAKDRLVH 295
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755563857 1211 QSQQLRESNQQLDlsacrltTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLES 1271
Cdd:pfam15742 296 EVEQRDERIKQLE-------NEIGILQQQSEKEKAFQKQVTAQNEILLLEKRKLLEQLTEQ 349
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
842-1073 |
4.51e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 4.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 842 AQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRY 921
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 922 RHLEQRLEAELQAASTSKEEALMELKARAlqleeeliqlrQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAA 1001
Cdd:COG4942 100 EAQKEELAELLRALYRLGRQPPLALLLSP-----------EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755563857 1002 LQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETR 1073
Cdd:COG4942 169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1037-1303 |
4.63e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 51.28 E-value: 4.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1037 LQAEKSMMEMQGQELHRKLgvleeevraarrAQEETRGQQQALLRDHEALVQLQ-----RRQETELEGLLVRHRDLKANM 1111
Cdd:pfam17380 278 VQHQKAVSERQQQEKFEKM------------EQERLRQEKEEKAREVERRRKLEeaekaRQAEMDRQAAIYAEQERMAME 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1112 RALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLM----QDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGEL 1187
Cdd:pfam17380 346 RERELERIRQEERKRELERIRQEEIAMEISRMRELERLQmerqQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1188 QGERGELRSR-LARLELERAQlEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEvqalsrENRELLE 1266
Cdd:pfam17380 426 RAEQEEARQReVRRLEEERAR-EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE------QRRKILE 498
|
250 260 270
....*....|....*....|....*....|....*..
gi 755563857 1267 RSLESRDHLHREQreyldqlnalrREKQKLVEKIMDQ 1303
Cdd:pfam17380 499 KELEERKQAMIEE-----------ERKRKLLEKEMEE 524
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
278-489 |
5.83e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 5.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 278 EVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSaqakRAELYREEAEALRERAGRLPRLQEELRRCREKlQAAEVFKGQ 357
Cdd:COG4913 222 DTFEAADALVEHFDDLERAHEALEDAREQIELLE----PIRELAERYAAARERLAELEYLRAALRLWFAQ-RRLELLEAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 358 LEEERVLSEALEASKVLLEEQLEVARERSARLHETQRENLLlrTRLGEAHADLDSLRHQLEQLVEENVELELELQRSLEP 437
Cdd:COG4913 297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG--DRLEQLEREIERLERELEERERRRARLEALLAALGLP 374
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 755563857 438 PPGSPGE-ASLPGAAPSLQDEVREAEAG---RLRAVERENRELRGQLQMLQAQLGS 489
Cdd:COG4913 375 LPASAEEfAALRAEAAALLEALEEELEAleeALAEAEAALRDLRRELRELEAEIAS 430
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1128-1300 |
9.46e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 9.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1128 LQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQ 1207
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1208 LEIQSQQLRESNQQLDLSACRLTTQCEL---------------------LTQLRSAQEEENRQLLAEVQALsrenRELLE 1266
Cdd:COG4942 95 LRAELEAQKEELAELLRALYRLGRQPPLalllspedfldavrrlqylkyLAPARREQAEELRADLAELAAL----RAELE 170
|
170 180 190
....*....|....*....|....*....|....
gi 755563857 1267 RSLESRDHLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARL 204
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
845-1222 |
1.04e-05 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 50.07 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 845 EAAEQQVQALESQVRCHLEEAEREHAEKQALRE---ELEKAVLRGQELGDRLEHLQEELEQaalerqkfLQEQ----ENQ 917
Cdd:pfam05622 10 DELAQRCHELDQQVSLLQEEKNSLQQENKKLQErldQLESGDDSGTPGGKKYLLLQKQLEQ--------LQEEnfrlETA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 918 HQRYRHLEQRLEAELQAAStSKEEALMELKARALQLEEELIQLRQypvdlatgaragprtvetQNGRLIEVErnnATLVA 997
Cdd:pfam05622 82 RDDYRIKCEELEKEVLELQ-HRNEELTSLAEEAQALKDEMDILRE------------------SSDKVKKLE---ATVET 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 998 EKAALQgQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEM---QGQELHRKLgvlEEEVRAARRAQEETR- 1073
Cdd:pfam05622 140 YKKKLE-DLGDLRRQVKLLEERNAEYMQRTLQLEEELKKANALRGQLETykrQVQELHGKL---SEESKKADKLEFEYKk 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1074 --GQQQALLRDHEALV----------------QLQRRQETELEGLLVRHRDLKANMRAlELAHRELQGRHEQLQAQ---- 1131
Cdd:pfam05622 216 leEKLEALQKEKERLIierdtlretneelrcaQLQQAELSQADALLSPSSDPGDNLAA-EIMPAEIREKLIRLQHEnkml 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1132 RANVEAQEVALLAERERLMQDGHRQR-GLEEELRRlqneherAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEI 1210
Cdd:pfam05622 295 RLGQEGSYRERLTELQQLLEDANRRKnELETQNRL-------ANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEE 367
|
410
....*....|..
gi 755563857 1211 QSQQLRESNQQL 1222
Cdd:pfam05622 368 HLEKLHEAQSEL 379
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
849-1253 |
1.08e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.56 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 849 QQVQALESQVRCHLEEAEREH----AEKQALREELE--------------KAVLRGQELGDRLEHLQEELEQAALERQKF 910
Cdd:pfam01576 15 QKVKERQQKAESELKELEKKHqqlcEEKNALQEQLQaetelcaeaeemraRLAARKQELEEILHELESRLEEEEERSQQL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 911 LQEQENQHQRYRHLEQRLEAElQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVER 990
Cdd:pfam01576 95 QNEKKKMQQHIQDLEEQLDEE-EAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 991 NNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAAR-RAQ 1069
Cdd:pfam01576 174 KAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALaRLE 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1070 EETRGQQQALLRDHEALVQLQRRQEtelegllvrhrDLKANMRALELAHRELQGRHEQLQAQRANVE------AQEVALL 1143
Cdd:pfam01576 254 EETAQKNNALKKIRELEAQISELQE-----------DLESERAARNKAEKQRRDLGEELEALKTELEdtldttAAQQELR 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1144 AERERlmQDGHRQRGLEEELRR----LQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESN 1219
Cdd:pfam01576 323 SKREQ--EVTELKKALEEETRSheaqLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAK 400
|
410 420 430
....*....|....*....|....*....|....
gi 755563857 1220 QQLDLSACRLTTQCELLtQLRSAQEEENRQLLAE 1253
Cdd:pfam01576 401 QDSEHKRKKLEGQLQEL-QARLSESERQRAELAE 433
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1126-1294 |
1.23e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1126 EQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLA--EVSRERGELQGERGELRSRLARLEL 1203
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1204 ERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREYL 1283
Cdd:COG4717 154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233
|
170
....*....|.
gi 755563857 1284 DQLNALRREKQ 1294
Cdd:COG4717 234 NELEAAALEER 244
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
876-1248 |
1.41e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.97 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 876 REELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRlEAELQAASTSKEEALMELKARALQLEE 955
Cdd:pfam02463 155 RLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQA-KKALEYYQLKEKLELEEEYLLYLDYLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 956 ELIQLRQypvDLATGARAGPRTVETQNGRLIEVERNNAT---LVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQE 1032
Cdd:pfam02463 234 LNEERID---LLQELLRDEQEEIESSKQEIEKEEEKLAQvlkENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKV 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1033 HSSRlQAEKSMMEMQGQELHRKLgvLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKanmr 1112
Cdd:pfam02463 311 DDEE-KLKESEKEKKKAEKELKK--EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES---- 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1113 alelAHRELQGRHEQLQAQRANVEAQEVALLAERERlmQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERG 1192
Cdd:pfam02463 384 ----ERLSSAAKLKEEELELKSEEEKEAQLLLELAR--QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQE 457
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 755563857 1193 ELRSRLaRLELERAQLEIQSQQLRESNQQLDLsACRLTTQCELLTQLRSAQEEENR 1248
Cdd:pfam02463 458 LKLLKD-ELELKKSEDLLKETQLVKLQEQLEL-LLSRQKLEERSQKESKARSGLKV 511
|
|
| MAP70 |
pfam07058 |
Microtubule-associated protein 70; This family represents a family of plant ... |
854-1107 |
1.50e-05 |
|
Microtubule-associated protein 70; This family represents a family of plant microtubule-associated proteins of size 70 kDa. The proteins contain four predicted coiled-coil domains, and truncation studies identify a central domain that targets the proteins to microtubules. It has no predicted trans-membrane domains, and the region between the coils from approximately residues 240-483 is the targetting region.
Pssm-ID: 399798 [Multi-domain] Cd Length: 544 Bit Score: 49.43 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 854 LESQVRCHLEEAEREHAEKQALRE---ELEKAVLrgqELGDRLEHLQEELEQA-ALERQKFLQEQENQHQRYRHLEQRLE 929
Cdd:pfam07058 12 LENEVRDKDRELGEALAEIKALRLserLKEKAVE---ELTDELLKLDEKLKASeNLLESKNLEIKKINDEKKAALAAQFA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 930 AELQAA---STSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAeKAALQGQL 1006
Cdd:pfam07058 89 AEATLRrvhAAQKDEDMPPIEAILAPLEAELKLARQEINKLQDDNKALDRLTKSKEAALLEAERAVQIALA-KASLVDDL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1007 QHlegqlgslqgRAQELLLQSQRAQEHSSRLQAeksmMEMQgqelhrKLGVLEEEVRAARRAQEETrgqqQALLRDHEAL 1086
Cdd:pfam07058 168 QN----------KNQELMKQIEICQEENKILDK----AHRQ------KVAEVEKLSQTVRELEEAV----LAGGAAANAV 223
|
250 260
....*....|....*....|.
gi 755563857 1087 VQLQRRQETELEGLLVRHRDL 1107
Cdd:pfam07058 224 RDYQRKVKEMNEERRTLEREL 244
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
726-1281 |
1.63e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 49.72 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 726 VSAIPEEQALRDE-VAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDT 804
Cdd:pfam05483 270 ANQLEEKTKLQDEnLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSF 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 805 ASLELEAASREREALAEAlaaagrERRQWERDGPRLRaqVEAAEQQVQALEsqvrchLEEAEREHAEKQALREELEKAVL 884
Cdd:pfam05483 350 VVTEFEATTCSLEELLRT------EQQRLEKNEDQLK--IITMELQKKSSE------LEEMTKFKNNKEVELEELKKILA 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 885 RGQELGD---RLEHLQEELEQAALERQKFLQEQENQhqryrhlEQRLEAELQAASTSKEEALMELKARALQLEEELIQlr 961
Cdd:pfam05483 416 EDEKLLDekkQFEKIAEELKGKEQELIFLLQAREKE-------IHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK-- 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 962 qypvdlatgaragpRTVETQNGRLIEVErnNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAE- 1040
Cdd:pfam05483 487 --------------NIELTAHCDKLLLE--NKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDEl 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1041 ---KSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRAlela 1117
Cdd:pfam05483 551 esvREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSA---- 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1118 hrelqgRHEQLQAQRANVEAQEVALLAERERL--MQDGHRQ----RGLEEElrRLQNEHERAQMLLAEVSRERGELQGE- 1190
Cdd:pfam05483 627 ------ENKQLNAYEIKVNKLELELASAKQKFeeIIDNYQKeiedKKISEE--KLLEEVEKAKAIADEAVKLQKEIDKRc 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1191 RGELRSRLARLELERAQLEiqsQQLRESNQQLDLSACRLTTQcellTQLRSAQEEENRQLLAEVQALSREnrelLERSLE 1270
Cdd:pfam05483 699 QHKIAEMVALMEKHKHQYD---KIIEERDSELGLYKNKEQEQ----SSAKAALEIELSNIKAELLSLKKQ----LEIEKE 767
|
570
....*....|.
gi 755563857 1271 SRDHLHREQRE 1281
Cdd:pfam05483 768 EKEKLKMEAKE 778
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
864-1260 |
1.66e-05 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 49.80 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 864 EAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLeaelqaastSKEEAL 943
Cdd:PRK10246 413 AALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQL---------ADVKTI 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 944 MELKARALQLEEELIQLRQYPVDLATGARAGPR-------TVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSL 1016
Cdd:PRK10246 484 CEQEARIKDLEAQRAQLQAGQPCPLCGSTSHPAveayqalEPGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRD 563
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1017 QGRAQELLLQSQ----RAQEHSSRLQAEKSMME-----MQGQELHRKL-----------GVLEEEVRAARRAQEETRGQQ 1076
Cdd:PRK10246 564 ESEAQSLRQEEQaltqQWQAVCASLNITLQPQDdiqpwLDAQEEHERQlrllsqrhelqGQIAAHNQQIIQYQQQIEQRQ 643
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1077 QAL--------------------LRDHEALVQLQRRQETELEGLLVRHRDLKANMRAL-----------ELAHRELQGRH 1125
Cdd:PRK10246 644 QQLltalagyaltlpqedeeaswLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLpqsddlphseeTVALDNWRQVH 723
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1126 EQ---LQAQRANVEAQEVallAERER--------------------------LMQDGHRQRgLEEELRRLQNEHERAQML 1176
Cdd:PRK10246 724 EQclsLHSQLQTLQQQDV---LEAQRlqkaqaqfdtalqasvfddqqaflaaLLDEETLTQ-LEQLKQNLENQRQQAQTL 799
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1177 LAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNqqldlsacrlTTQCELLTQLRsaQEEENRQ----LLA 1252
Cdd:PRK10246 800 VTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQLRENT----------TRQGEIRQQLK--QDADNRQqqqaLMQ 867
|
....*...
gi 755563857 1253 EVQALSRE 1260
Cdd:PRK10246 868 QIAQATQQ 875
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1028-1300 |
1.70e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.35 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1028 QRAQEHSSRLQAEKSMMEMqgqELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDL 1107
Cdd:pfam05557 5 IESKARLSQLQNEKKQMEL---EHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1108 KANMRALELAHRElqgrHEQLQAqranvEAQEVallaererlmqdghrQRGLEEELRRLQNEHERAQMLLAEVSRERGEL 1187
Cdd:pfam05557 82 KKYLEALNKKLNE----KESQLA-----DAREV---------------ISCLKNELSELRRQIQRAELELQSTNSELEEL 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1188 QGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENR--QLLAEVQAL-------- 1257
Cdd:pfam05557 138 QERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARipELEKELERLrehnkhln 217
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 755563857 1258 -SRENRELLERSLES-RDHLHREQrEYLDQLNALRREKQKLVEKI 1300
Cdd:pfam05557 218 eNIENKLLLKEEVEDlKRKLEREE-KYREEAATLELEKEKLEQEL 261
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1041-1247 |
1.71e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.63 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1041 KSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEaLVQLQRRQETELEGLlvrhRDLKANMRALELAHRE 1120
Cdd:COG3206 163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNG-LVDLSEEAKLLLQQL----SELESQLAEARAELAE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1121 LQGRHEQLQAQRA----------------NVEAQEVALLAERERLMQ---DGHRQ-RGLEEELRRLQNE-HERAQMLLAE 1179
Cdd:COG3206 238 AEARLAALRAQLGsgpdalpellqspviqQLRAQLAELEAELAELSArytPNHPDvIALRAQIAALRAQlQQEAQRILAS 317
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755563857 1180 VSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTqceLLTQLRSAQEEEN 1247
Cdd:COG3206 318 LEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES---LLQRLEEARLAEA 382
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
657-1301 |
1.73e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 49.96 E-value: 1.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 657 AELTLREPLKDQKALDRELELSKQQKETGRHEQRPKGLESKLGPQKPQQTSEgvpdaWSREeptpgetLVSAIPEEQALR 736
Cdd:PRK04863 445 EEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWD-----VARE-------LLRRLREQRHLA 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 737 DEVAQLRREVAGLEVKLQAQaqrleaRSAEALclseeLAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAASRER 816
Cdd:PRK04863 513 EQLQQLRMRLSELEQRLRQQ------QRAERL-----LAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERR 581
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 817 EALAEALAAAGRERRQWERDGP----------RLRAQVEAAEQQVQALESQVRCHLEEaERE--------HAEKQALREE 878
Cdd:PRK04863 582 MALRQQLEQLQARIQRLAARAPawlaaqdalaRLREQSGEEFEDSQDVTEYMQQLLER-EREltverdelAARKQALDEE 660
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 879 LEKAVLRGQELGDRLEHLQE--------------ELEQAA-----------------LERQKflqeqenqhqryRHLEQR 927
Cdd:PRK04863 661 IERLSQPGGSEDPRLNALAErfggvllseiyddvSLEDAPyfsalygparhaivvpdLSDAA------------EQLAGL 728
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 928 ---------LEAELQAASTSKEEAlmELKARALQLEEELIQLR--QYPVDLATGARAGPRTVETQNGRLIEVERNNATLV 996
Cdd:PRK04863 729 edcpedlylIEGDPDSFDDSVFSV--EELEKAVVVKIADRQWRysRFPEVPLFGRAAREKRIEQLRAEREELAERYATLS 806
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 997 AEKAALQGQLQHL----------------EGQLGSLQGRAQELL--LQSQRAQEHSSRLQAEKSMMEMQG-QELHRKLGV 1057
Cdd:PRK04863 807 FDVQKLQRLHQAFsrfigshlavafeadpEAELRQLNRRRVELEraLADHESQEQQQRSQLEQAKEGLSAlNRLLPRLNL 886
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1058 LEEEVRAARraQEETRGQQQALLRDhEALVQLQRRQETELEGLLvrhrdlkANMRALELAHRELQGRHEQLQAQRANVEA 1137
Cdd:PRK04863 887 LADETLADR--VEEIREQLDEAEEA-KRFVQQHGNALAQLEPIV-------SVLQSDPEQFEQLKQDYQQAQQTQRDAKQ 956
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1138 QEVALlaerERLMQdghrqrgleeelRRLQNEHERAQMLLAEVSrergelqgergELRSRLarleleRAQLEIQSQQLRE 1217
Cdd:PRK04863 957 QAFAL----TEVVQ------------RRAHFSYEDAAEMLAKNS-----------DLNEKL------RQRLEQAEQERTR 1003
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1218 SNQQLDLSACRLTTQCELLTQLRS---AQEEENRQLLAEVQALS-RENRELLERSLESRDHLH------REQREYLD-QL 1286
Cdd:PRK04863 1004 AREQLRQAQAQLAQYNQVLASLKSsydAKRQMLQELKQELQDLGvPADSGAEERARARRDELHarlsanRSRRNQLEkQL 1083
|
730
....*....|....*
gi 755563857 1287 NALRREKQKLVEKIM 1301
Cdd:PRK04863 1084 TFCEAEMDNLTKKLR 1098
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
872-1099 |
2.17e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.24 E-value: 2.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 872 KQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQE--NQHQRYRHLEQRLeAELQAASTSKEEALMELKAR 949
Cdd:COG3206 163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQL-SELESQLAEARAELAEAEAR 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 950 ALQLEEELIQLRQYPVDLAtgaragprtvetQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQ-SQ 1028
Cdd:COG3206 242 LAALRAQLGSGPDALPELL------------QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQlQQ 309
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755563857 1029 RAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEEtrgqQQALLRDHEALVQ-----LQRRQETELEG 1099
Cdd:COG3206 310 EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE----LRRLEREVEVARElyeslLQRLEEARLAE 381
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
840-1229 |
2.26e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 49.57 E-value: 2.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 840 LRAQVEAAEQQVQALESQVRchLEEAEREHAEKQALREELEKAV-------------LRGQELGDRLEHLQEELEQAALE 906
Cdd:COG3096 288 LELRRELFGARRQLAEEQYR--LVEMARELEELSARESDLEQDYqaasdhlnlvqtaLRQQEKIERYQEDLEELTERLEE 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 907 RQKFLQEQENQHQRYRHLEQRLEAELQAASTS---KEEALMELKARALQLEEELIQLRQypvdlatgARAgprtvetqng 983
Cdd:COG3096 366 QEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQladYQQALDVQQTRAIQYQQAVQALEK--------ARA---------- 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 984 RLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQgraQELLLQSQRAQEHSSRLQAEKSMM-EMQGQELHrklGVLEEEV 1062
Cdd:COG3096 428 LCGLPDLTPENAEDYLAAFRAKEQQATEEVLELE---QKLSVADAARRQFEKAYELVCKIAgEVERSQAW---QTARELL 501
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1063 RAAR--RAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEV 1140
Cdd:COG3096 502 RRYRsqQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRS 581
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1141 ALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELrsrlarLELERaQLEIQSQQLRESNQ 1220
Cdd:COG3096 582 ELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQL------LERER-EATVERDELAARKQ 654
|
....*....
gi 755563857 1221 QLDLSACRL 1229
Cdd:COG3096 655 ALESQIERL 663
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
273-1161 |
3.76e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 48.63 E-value: 3.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 273 RRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEA-EALRERAGRLPRLQEELRRCREKLQAA 351
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNAlKKIRELEAQISELQEDLESERAARNKA 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 352 EvfkgqlEEERVLSEALEASKVLLE--------------------EQLEVARERSARLHETQRENllLRTRLGEAhadLD 411
Cdd:pfam01576 291 E------KQRRDLGEELEALKTELEdtldttaaqqelrskreqevTELKKALEEETRSHEAQLQE--MRQKHTQA---LE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 412 SLRHQLEQLVEENVELELELQrslepppgspgeaSLPGAAPSLQDEVREAEAGRLRaVERENRELRGQLQMLQAQLGSQH 491
Cdd:pfam01576 360 ELTEQLEQAKRNKANLEKAKQ-------------ALESENAELQAELRTLQQAKQD-SEHKRKKLEGQLQELQARLSESE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 492 PLLEEQRE--NSRQPPVPNRDPATPSA--LHHSPQSPACQIGGEGSESLDLPSPASYSDITRSPKCSQAPDSHPELESPL 567
Cdd:pfam01576 426 RQRAELAEklSKLQSELESVSSLLNEAegKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQL 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 568 -------QMVSQDPQTSDQALQESDPTVETH-QCLEksghrvplqspivwdppQGPEVRIEVQELLGETGSREAPQgelv 639
Cdd:pfam01576 506 eeeeeakRNVERQLSTLQAQLSDMKKKLEEDaGTLE-----------------ALEEGKKRLQRELEALTQQLEEK---- 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 640 hKAQVLKQESPKCRPRSAELTLREPLKDQKALDRELElsKQQKETGRHEQRPKGLESKLGPQKPQQTSEgvpdawSREEP 719
Cdd:pfam01576 565 -AAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE--KKQKKFDQMLAEEKAISARYAEERDRAEAE------AREKE 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 720 TPGETLVSAIPEEQALRDEVAQLRREvaglevkLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLR 799
Cdd:pfam01576 636 TRALSLARALEEALEAKEELERTNKQ-------LRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 800 EAVDTASLELEAASRERealaealaaagreRRQWERDgprLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREEL 879
Cdd:pfam01576 709 QATEDAKLRLEVNMQAL-------------KAQFERD---LQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAK 772
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 880 EKAVLRGQELGDRLEHLQEELEQaALERQKFLQEQENQHQRyrhleqrleaELQAASTSKEEALM---ELKARALQLEEE 956
Cdd:pfam01576 773 KKLELDLKELEAQIDAANKGREE-AVKQLKKLQAQMKDLQR----------ELEEARASRDEILAqskESEKKLKNLEAE 841
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 957 LIQLRQypvDLATGARAgPRTVETQNGRLIEVERNNAT----LVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQE 1032
Cdd:pfam01576 842 LLQLQE---DLAASERA-RRQAQQERDELADEIASGASgksaLQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTL 917
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1033 HSSRLQAE--------------KSMMEMQGQELHRKLGVLEEEVRA----------ARRAQEETRGQQQAllRDHEALVQ 1088
Cdd:pfam01576 918 QVEQLTTElaaerstsqksesaRQQLERQNKELKAKLQEMEGTVKSkfkssiaaleAKIAQLEEQLEQES--RERQAANK 995
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755563857 1089 LQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLmqdghrQRGLEE 1161
Cdd:pfam01576 996 LVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKL------QRELDD 1062
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
983-1296 |
3.87e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.97 E-value: 3.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 983 GRLIEVERNNATLVAEKAALQGQL----QHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVL 1058
Cdd:pfam07888 34 NRLEECLQERAELLQAQEAANRQRekekERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEEL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1059 EEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQ----------- 1127
Cdd:pfam07888 114 SEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQteeelrslske 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1128 LQAQRANVEAQEVALLAERERLMQDGHR-----QRGLE-----EELRRLQNEHERAQMLLAEVSRERGELQGERGELRSR 1197
Cdd:pfam07888 194 FQELRNSLAQRDTQVLQLQDTITTLTQKlttahRKEAEneallEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAE 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1198 LARLELERAQLEIqsqQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHR 1277
Cdd:pfam07888 274 LHQARLQAAQLTL---QLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGR 350
|
330
....*....|....*....
gi 755563857 1278 EQREYLDQLNALRREKQKL 1296
Cdd:pfam07888 351 EKDCNRVQLSESRRELQEL 369
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
864-1308 |
4.32e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.18 E-value: 4.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 864 EAEREHAEK--QALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEE 941
Cdd:pfam05483 175 EYEREETRQvyMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKEN 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 942 ALMELkarALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATL---VAEKAALQGQLQhlegqlgsLQG 1018
Cdd:pfam05483 255 KMKDL---TFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLqrsMSTQKALEEDLQ--------IAT 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1019 RAQELLLQSQRAQ-EHSSRLQAEKSMMEmqgQELHRKLGVLEEEVRAARRAQEETRGQQQALL-------RDHEALVQLQ 1090
Cdd:pfam05483 324 KTICQLTEEKEAQmEELNKAKAAHSFVV---TEFEATTCSLEELLRTEQQRLEKNEDQLKIITmelqkksSELEEMTKFK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1091 RRQETELEGL---LVRHRDLKANMRALELAHRELQGRHEQLqaqranveaqeVALLAERERLMQDghrqrgLEEELRRLQ 1167
Cdd:pfam05483 401 NNKEVELEELkkiLAEDEKLLDEKKQFEKIAEELKGKEQEL-----------IFLLQAREKEIHD------LEIQLTAIK 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1168 NEHeraQMLLAEVSRERGELQGER---GELRSRLARLELERAQL--EIQSQQLRESNQQLDLSACRLTTQcELLTQLRSA 1242
Cdd:pfam05483 464 TSE---EHYLKEVEDLKTELEKEKlknIELTAHCDKLLLENKELtqEASDMTLELKKHQEDIINCKKQEE-RMLKQIENL 539
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755563857 1243 QEEENrQLLAEVQALSRENREL-------LERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLE 1308
Cdd:pfam05483 540 EEKEM-NLRDELESVREEFIQKgdevkckLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIE 611
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
976-1296 |
5.76e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.03 E-value: 5.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 976 RTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQG--RAQElllQSQRAQEHSSRLQAEKSMMEMQGQELHR 1053
Cdd:PRK04863 300 RQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTalRQQE---KIERYQADLEELEERLEEQNEVVEEADE 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1054 KLGVLEEEVRAARRAQEETRGQqqalLRDH-EALVQLQRR--QETELEGLLVRHRDLKANMralELAHRELQGRHEQLQA 1130
Cdd:PRK04863 377 QQEENEARAEAAEEEVDELKSQ----LADYqQALDVQQTRaiQYQQAVQALERAKQLCGLP---DLTADNAEDWLEEFQA 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1131 QRANVeAQEVALLAERERLMQDGHRQ--------RGLEEELRRLQnEHERAQMLLAEVSRERGELQgERGELRSRLARLE 1202
Cdd:PRK04863 450 KEQEA-TEELLSLEQKLSVAQAAHSQfeqayqlvRKIAGEVSRSE-AWDVARELLRRLREQRHLAE-QLQQLRMRLSELE 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1203 LERAQLEIQSQQLRESNQQLDLSacrlTTQCELLTQLRSAQEeenrqllAEVQALSRENRELLERSLESRDHLhreqrey 1282
Cdd:PRK04863 527 QRLRQQQRAERLLAEFCKRLGKN----LDDEDELEQLQEELE-------ARLESLSESVSEARERRMALRQQL------- 588
|
330
....*....|....
gi 755563857 1283 lDQLNALRREKQKL 1296
Cdd:PRK04863 589 -EQLQARIQRLAAR 601
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
1114-1226 |
7.00e-05 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 46.96 E-value: 7.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1114 LELAHRELQGRHEQLQAQRANVEAQEVALLAE---RERLMQDGHRQRGLEEELRRLQNEHERAQMLLAE--VSRErgELQ 1188
Cdd:COG1566 74 ARLDPTDLQAALAQAEAQLAAAEAQLARLEAElgaEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKgaVSQQ--ELD 151
|
90 100 110
....*....|....*....|....*....|....*...
gi 755563857 1189 GERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSA 1226
Cdd:COG1566 152 EARAALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQA 189
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
261-419 |
7.95e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 7.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 261 LALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAGRLPRLQEE 340
Cdd:COG3206 210 LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPN 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 341 ---LRRCREKLQAAEVFKGQLEEERVLS-----EALEASKVLLEEQLEVARERSARLHETQRENLLLRTRLGEAHADLDS 412
Cdd:COG3206 290 hpdVIALRAQIAALRAQLQQEAQRILASleaelEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
|
....*..
gi 755563857 413 LRHQLEQ 419
Cdd:COG3206 370 LLQRLEE 376
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
94-182 |
9.02e-05 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 44.46 E-value: 9.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 94 RMWNLCHLWGRLRDFYQEELQLLILSPP-PDLQTMG--CDPFseeavdELESILRLLLGASVQCEHRELFIRHIRGLSLD 170
Cdd:cd22225 61 KMSNLKKILQGIVDYYHEFLDQQISEFLlPDLNRIAehSDPV------ELGRLLQLILGCAVNCEKKQEHIQNIMTLEES 134
|
90
....*....|..
gi 755563857 171 VQSELAGAIQEV 182
Cdd:cd22225 135 VQHVVMTAIQEL 146
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
204-385 |
9.65e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 9.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 204 EELEMQLRSLTGMMSRLARERDLGAQRLAELLLEREPAHLLLPEAPANASAEGVSHHLAlQLTNAKAQLRRLRQEVEEKA 283
Cdd:COG4913 613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIA-ELEAELERLDASSDDLAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 284 EQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAGRLPRLQEELRrcreklqAAEVFKGQLEEERV 363
Cdd:COG4913 692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL-------LEERFAAALGDAVE 764
|
170 180
....*....|....*....|....
gi 755563857 364 --LSEALEASKVLLEEQLEVARER 385
Cdd:COG4913 765 reLRENLEERIDALRARLNRAEEE 788
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
262-487 |
1.17e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 262 ALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEA-LRERAGRLPRLQEE 340
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAeLAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 341 LRRCREKL--QAAEVFK-GQLEEERVL---SEALEASKVL--LEEQLEVARERSARLHETQRENLLLRTRLGEAHADLDS 412
Cdd:COG4942 99 LEAQKEELaeLLRALYRlGRQPPLALLlspEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755563857 413 LRHQLEQLVEENVELELELQRSLEpppgspgeaslpgaapSLQDEVREAEAgRLRAVERENRELRGQLQMLQAQL 487
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLA----------------RLEKELAELAA-ELAELQQEAEELEALIARLEAEA 236
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
732-1226 |
1.28e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 732 EQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHqeaeaqareqaRLREAVDTASLELEA 811
Cdd:pfam12128 421 ESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIE-----------RAREEQEAANAEVER 489
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 812 ASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQA--------LESQVRCHLEEAEREHAEKQALREELEKAV 883
Cdd:pfam12128 490 LQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPqagtllhfLRKEAPDWEQSIGKVISPELLHRTDLDPEV 569
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 884 LRGQELGDR-LEHLQEELEQAalerqkflqeqenQHQRYRHLEQRLEAELQAAstskEEALMELKARALQLEEELIQLRQ 962
Cdd:pfam12128 570 WDGSVGGELnLYGVKLDLKRI-------------DVPEWAASEEELRERLDKA----EEALQSAREKQAAAEEQLVQANG 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 963 yPVDLA----TGARAGPRTVETQNGRLIEVERN-----NATLVAEKAALQGQLQHLEGQLGSLqGRAQELLLQSQRAQEH 1033
Cdd:pfam12128 633 -ELEKAsreeTFARTALKNARLDLRRLFDEKQSekdkkNKALAERKDSANERLNSLEAQLKQL-DKKHQAWLEEQKEQKR 710
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1034 SSRLQAEKSMMEMQGqELHRKLGVLEEEVRAAR-RAQEETRGQQQALLRDHEAL---VQLQRRQETELEGLLVRHRDLKA 1109
Cdd:pfam12128 711 EARTEKQAYWQVVEG-ALDAQLALLKAAIAARRsGAKAELKALETWYKRDLASLgvdPDVIAKLKREIRTLERKIERIAV 789
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1110 NMRALELAHRELQGRHEQ----LQAQRANVEAQEVALLAERERLMQDGHRQRgleEELRRLQNEHERAQMLLAEvsrerg 1185
Cdd:pfam12128 790 RRQEVLRYFDWYQETWLQrrprLATQLSNIERAISELQQQLARLIADTKLRR---AKLEMERKASEKQQVRLSE------ 860
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 755563857 1186 ELQGERGELRsRLARLEL----ERAQLEI-----QSQQLRESNQQLDLSA 1226
Cdd:pfam12128 861 NLRGLRCEMS-KLATLKEdansEQAQGSIgerlaQLEDLKLKRDYLSESV 909
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
867-1284 |
1.54e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 867 REHAEKQALREELEKAVLrGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEA-LME 945
Cdd:COG4913 587 GTRHEKDDRRRIRSRYVL-GFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdVAS 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 946 LKARALQLEEELIQLRQYPVDLATgaragprtvetqngrlievernnatlvaekaalqgqlqhLEGQLGSLQGRAQELLL 1025
Cdd:COG4913 666 AEREIAELEAELERLDASSDDLAA---------------------------------------LEEQLEELEAELEELEE 706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1026 QSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRgQQQALLRDHEAlvQLQRRQETELEGLlvrHR 1105
Cdd:COG4913 707 ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEER-FAAALGDAVER--ELRENLEERIDAL---RA 780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1106 DLKANMRALELAHRELQGR-HEQLQAQRANVEAQEvALLAERERLMQDG-HRqrgLEEELRRLQNEHERAQM--LLAEVS 1181
Cdd:COG4913 781 RLNRAEEELERAMRAFNREwPAETADLDADLESLP-EYLALLDRLEEDGlPE---YEERFKELLNENSIEFVadLLSKLR 856
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1182 RERGELQGERGELRSRLARLEL---ERAQLEIQSQQLRESNqqldlsacrlttqcELLTQLRSAQeeENRQLLAEVQALS 1258
Cdd:COG4913 857 RAIREIKERIDPLNDSLKRIPFgpgRYLRLEARPRPDPEVR--------------EFRQELRAVT--SGASLFDEELSEA 920
|
410 420 430
....*....|....*....|....*....|
gi 755563857 1259 RENR--ELLERsLESRDHLH--REQREYLD 1284
Cdd:COG4913 921 RFAAlkRLIER-LRSEEEESdrRWRARVLD 949
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
134-476 |
1.61e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.47 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 134 EEAVDELESILRLLLGASVQCEHRELFIRHIRGLSLDVQSELAGAIQEVTQ--PGAGVVLALAGPESGELVAEELEMQLR 211
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEaaARLLLLLEAEADYEGFLEGVKAALLLA 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 212 SLTGMMSRLARERDLGAQRLAELLLEREPAHLLLPEAPANASAEGVSHHLALQLtnAKAQLRRLRQEVEEKAEQLLDSQA 291
Cdd:COG1196 518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA--GRATFLPLDKIRARAALAAALARG 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 292 EVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAGRLPRLQEELRRcREKLQAAEVFKGQLEEERVLSEALEAS 371
Cdd:COG1196 596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR-EVTLEGEGGSAGGSLTGGSRRELLAAL 674
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 372 KVLLEEQLEVARERSARLHETQRENLLLRTRLGEAHADLDSLRHQLEQLVEENVELELELQRSLEPPPGSPGEASLPGAA 451
Cdd:COG1196 675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754
|
330 340
....*....|....*....|....*
gi 755563857 452 PSLQDEVREAEAGRLRAVERENREL 476
Cdd:COG1196 755 ELPEPPDLEELERELERLEREIEAL 779
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
905-1226 |
1.63e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.27 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 905 LERQKFLQEQENQHQRYRHLEQRLEAElqaastsKEEALMELKARALQLEEELIQL----RQYPVDLATGARAGPRTVET 980
Cdd:pfam17380 278 VQHQKAVSERQQQEKFEKMEQERLRQE-------KEEKAREVERRRKLEEAEKARQaemdRQAAIYAEQERMAMEREREL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 981 QNGRLIEVERNNATLVAEKAALQ-GQLQHLEgqlgslqgraqELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLE 1059
Cdd:pfam17380 351 ERIRQEERKRELERIRQEEIAMEiSRMRELE-----------RLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQK 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1060 EEVRAARRAQEETRGQQ-QALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQ 1138
Cdd:pfam17380 420 VEMEQIRAEQEEARQREvRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1139 EV-----ALLAER------ERLMQDghRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERaq 1207
Cdd:pfam17380 500 ELeerkqAMIEEErkrkllEKEMEE--RQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERER-- 575
|
330
....*....|....*....
gi 755563857 1208 lEIQSQQLRESNQQLDLSA 1226
Cdd:pfam17380 576 -EMMRQIVESEKARAEYEA 593
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
724-986 |
1.64e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 724 TLVSAIPEEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVD 803
Cdd:COG4942 14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 804 TASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAV 883
Cdd:COG4942 94 ELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 884 LRGQELGDRLEHLQEELEQAALERQKflqeqenqhqryrhleqrLEAELQAASTSKEEALMELKARALQLEEELIQLRQY 963
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQK------------------LLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
250 260
....*....|....*....|...
gi 755563857 964 PVDLATGARAGPrtVETQNGRLI 986
Cdd:COG4942 236 AAAAAERTPAAG--FAALKGKLP 256
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
743-1292 |
1.72e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 46.27 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 743 RREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAASREREALAEA 822
Cdd:pfam05557 26 KRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREV 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 823 LAAAGRERRqwerdgpRLRAQVEAAEQQVQALESqvrchleeaerehaEKQALREELEKAVLRGQELGDRLEHLQEEleq 902
Cdd:pfam05557 106 ISCLKNELS-------ELRRQIQRAELELQSTNS--------------ELEELQERLDLLKAKASEAEQLRQNLEKQ--- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 903 aalerQKFLQEQEnqhQRYRHLEQRLeaELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQN 982
Cdd:pfam05557 162 -----QSSLAEAE---QRIKELEFEI--QSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 983 GRLIEVERNNATLvAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSR----------LQAEKSMMEMQGQELH 1052
Cdd:pfam05557 232 DLKRKLEREEKYR-EEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRieqlqqreivLKEENSSLTSSARQLE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1053 RKLGVLEEEVRAARRAQEEtrgqQQALLRDHEALVQ-LQRR-----QETELEGLLVRHRDLKANM----RALELAHRELQ 1122
Cdd:pfam05557 311 KARRELEQELAQYLKKIED----LNKKLKRHKALVRrLQRRvllltKERDGYRAILESYDKELTMsnysPQLLERIEEAE 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1123 GRHEQLQAQRANVEAQEVALLAErerlmQDGHRQRG--LEEEL--RRLQNEHERAQMLLAEVS---RERGELQGERGELR 1195
Cdd:pfam05557 387 DMTQKMQAHNEEMEAQLSVAEEE-----LGGYKQQAqtLERELqaLRQQESLADPSYSKEEVDslrRKLETLELERQRLR 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1196 SRLARLELERAQLEIQsqqlresnQQLDLSACR-LTTQCELLTQLRSAQEEENRQLLAEVQALSRENReLLERSLESRDH 1274
Cdd:pfam05557 462 EQKNELEMELERRCLQ--------GDYDPKKTKvLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLK-KLEDDLEQVLR 532
|
570
....*....|....*....
gi 755563857 1275 LHREQREYLDQ-LNALRRE 1292
Cdd:pfam05557 533 LPETTSTMNFKeVLDLRKE 551
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-397 |
2.09e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.29 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 203 AEELEMQLRSLTGMMSRLARERDLGAQRLAELLLEREPAH----LLLPEAPANASAEGVSHHlalQLTNAKAQLRRLRQE 278
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARieevMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEE 1630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 279 VEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKR--------AELYREEAEALRERAGRLPRLQEELRRCRE--KL 348
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKkaeedkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEElkKK 1710
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 755563857 349 QAAEVFKGQ--LEEERVLSEALEASKVLLEEQLEVARErsARLHETQRENL 397
Cdd:PTZ00121 1711 EAEEKKKAEelKKAEEENKIKAEEAKKEAEEDKKKAEE--AKKDEEEKKKI 1759
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
265-500 |
2.27e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.80 E-value: 2.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 265 LTNAKAQLRRLRQEVEEKaeqlldsqaEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAgrlprlQEELRRC 344
Cdd:PRK02224 182 LSDQRGSLDQLKAQIEEK---------EEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEA------DEVLEEH 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 345 REKLQAAEVFKGQLEEERVLSEALEASKVLLEEQLEVARERSARLhETQRENLLLRTRLGEAHA------------DLDS 412
Cdd:PRK02224 247 EERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL-EEERDDLLAEAGLDDADAeavearreeledRDEE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 413 LRHQLEQLVEENVELELELQRSLEPPPGSPGEAS-LPGAAPSLQDEVREAEA------GRLRAVERENRELRGQLQMLQA 485
Cdd:PRK02224 326 LRDRLEECRVAAQAHNEEAESLREDADDLEERAEeLREEAAELESELEEAREavedrrEEIEELEEEIEELRERFGDAPV 405
|
250
....*....|....*
gi 755563857 486 QLGSQHPLLEEQREN 500
Cdd:PRK02224 406 DLGNAEDFLEELREE 420
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
976-1292 |
2.29e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 976 RTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMmemqgQELHRKL 1055
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAEL-----AELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1056 GVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRR----QETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQ 1131
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELAELQEELEELLEQlslaTEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1132 RANVEAQEVALlAERERLMQDGHRQRGL----------EEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARL 1201
Cdd:COG4717 229 LEQLENELEAA-ALEERLKEARLLLLIAaallallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1202 ELERAQLEIQSQQLRESNQQLDLSAC-----------RLTTQCELLTQLRSAQEE--------ENRQLLAEVQALSREnr 1262
Cdd:COG4717 308 QALPALEELEEEELEELLAALGLPPDlspeellelldRIEELQELLREAEELEEElqleeleqEIAALLAEAGVEDEE-- 385
|
330 340 350
....*....|....*....|....*....|
gi 755563857 1263 ellerSLESRDHLHREQREYLDQLNALRRE 1292
Cdd:COG4717 386 -----ELRAALEQAEEYQELKEELEELEEQ 410
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
730-1301 |
2.36e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 730 PEEQALRDEVAQLRREVAGLEvklqaqaqRLEARSAEALCLSEELAQArrtEAEAHQEAEAQAREQARLREAVDTASLEL 809
Cdd:COG3096 505 RSQQALAQRLQQLRAQLAELE--------QRLRQQQNAERLLEEFCQR---IGQQLDAAEELEELLAELEAQLEELEEQA 573
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 810 EAASREREALAEALAAAGRERRQWERDGP----------RLRAQVEAA---EQQVQALESQVRCHLEEAEREHAEKQALR 876
Cdd:COG3096 574 AEAVEQRSELRQQLEQLRARIKELAARAPawlaaqdaleRLREQSGEAladSQEVTAAMQQLLEREREATVERDELAARK 653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 877 EELEKAVLR-----GQE------LGDRL--EHLQEELEQAALERQKFLQeqenqhQRY----------------RHLEQR 927
Cdd:COG3096 654 QALESQIERlsqpgGAEdprllaLAERLggVLLSEIYDDVTLEDAPYFS------ALYgparhaivvpdlsavkEQLAGL 727
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 928 ---------LEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAE 998
Cdd:COG3096 728 edcpedlylIEGDPDSFDDSVFDAEELEDAVVVKLSDRQWRYSRFPEVPLFGRAAREKRLEELRAERDELAEQYAKASFD 807
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 999 KAALQGQLQHLEGQLGS----------------LQGRAQEL--LLQSQRAQEHSSRLQAEKSMmemQGQELHRKL----G 1056
Cdd:COG3096 808 VQKLQRLHQAFSQFVGGhlavafapdpeaelaaLRQRRSELerELAQHRAQEQQLRQQLDQLK---EQLQLLNKLlpqaN 884
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1057 VLEEEVRAARRaqEETRGQQQALLRDhEALVQLQRRQETELEGLLvrhrdlkANMRALELAHRELQGRHEQLQAQRANVE 1136
Cdd:COG3096 885 LLADETLADRL--EELREELDAAQEA-QAFIQQHGKALAQLEPLV-------AVLQSDPEQFEQLQADYLQAKEQQRRLK 954
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1137 AQEVALlaerERLMQdghrqrgleeelRRLQNEHERAQMLLAEVSrergelqgergELRSRLarleleRAQLEIQSQQLR 1216
Cdd:COG3096 955 QQIFAL----SEVVQ------------RRPHFSYEDAVGLLGENS-----------DLNEKL------RARLEQAEEARR 1001
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1217 ESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLA---EVQALS-RENRELLERSLESRDHLH------REQREYLD-Q 1285
Cdd:COG3096 1002 EAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQEleqELEELGvQADAEAEERARIRRDELHeelsqnRSRRSQLEkQ 1081
|
650
....*....|....*.
gi 755563857 1286 LNALRREKQKLVEKIM 1301
Cdd:COG3096 1082 LTRCEAEMDSLQKRLR 1097
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
731-1100 |
2.44e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 2.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSE---ELAQARRTEAEAHQEAEAQAREQ---ARLREAVDT 804
Cdd:COG3096 279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSAresDLEQDYQAASDHLNLVQTALRQQekiERYQEDLEE 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 805 ASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVE--------------AAEQQVQALE-SQVRCHLEEAEREH 869
Cdd:COG3096 359 LTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyqqaldvqqtraiQYQQAVQALEkARALCGLPDLTPEN 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 870 AEkqalrEELEKAVLRGQELGDRLEHLQEELEQAALERQKF----------------------LQEQENQHQRYRHLEQR 927
Cdd:COG3096 439 AE-----DYLAAFRAKEQQATEEVLELEQKLSVADAARRQFekayelvckiageversqawqtARELLRRYRSQQALAQR 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 928 LEAelQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGAragPRTVETQNGRLIEVERNNATLVAEKAALQGQLQ 1007
Cdd:COG3096 514 LQQ--LRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEEL---EELLAELEAQLEELEEQAAEAVEQRSELRQQLE 588
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1008 HLEGQLGSLQGRAQELLlqsqRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALV 1087
Cdd:COG3096 589 QLRARIKELAARAPAWL----AAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLS 664
|
410
....*....|...
gi 755563857 1088 QLQRRQETELEGL 1100
Cdd:COG3096 665 QPGGAEDPRLLAL 677
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
188-499 |
2.53e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.83 E-value: 2.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 188 GVVLALAGPESGELVAEELEMQLRSLTGMMSRLARERDLGAQRLAEL--------LLEREPAHLLLPEAPANASAEGVSH 259
Cdd:TIGR02169 665 GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELsdasrkigEIEKEIEQLEQEEEKLKERLEELEE 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 260 HL-ALQ--LTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAeALRERAGRLPR 336
Cdd:TIGR02169 745 DLsSLEqeIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEA-RLREIEQKLNR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 337 LQEELRRCREKLQAAEVFKGQLEEERV-LSEALEASKVLLEEQLEVARERSARLHE---------TQRENLL-----LRT 401
Cdd:TIGR02169 824 LTLEKEYLEKEIQELQEQRIDLKEQIKsIEKEIENLNGKKEELEEELEELEAALRDlesrlgdlkKERDELEaqlreLER 903
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 402 RLGEAHADLDSLRHQLEQ-------LVEENVELELELQRSLEPPPGSPGEASLPGAAPSLQDEVREAEAGRLRAVERENR 474
Cdd:TIGR02169 904 KIEELEAQIEKKRKRLSElkakleaLEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEE 983
|
330 340
....*....|....*....|....*
gi 755563857 475 ELRGQLqmlqaQLGSQHPLLEEQRE 499
Cdd:TIGR02169 984 VLKRLD-----ELKEKRAKLEEERK 1003
|
|
| MASE1 |
COG3447 |
Integral membrane sensor domain MASE1 [Signal transduction mechanisms]; |
828-1171 |
2.91e-04 |
|
Integral membrane sensor domain MASE1 [Signal transduction mechanisms];
Pssm-ID: 442670 [Multi-domain] Cd Length: 637 Bit Score: 45.57 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDgpRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALER 907
Cdd:COG3447 291 AERRRQRLR--ERELALRAALELLALGLLLAALDDALLLLNARGLLLLALSLAALLLLRLALLLLLLALDALLLLLADDD 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 908 QKFLQEQENQHQRYRHLEQRLEAELQ-AASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLI 986
Cdd:COG3447 369 RGELRGDLLRRRGATRLGAVVARLLRrSGGRGEEVVVLLVIAQVEEALELALRERREERLLERLALALELLAITAALLAA 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 987 EVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQ---RAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVR 1063
Cdd:COG3447 449 ALLLALADLLLLLLAEAAQLLARALLLGLDRLLADAALAALAalaDLLGALLSAGLRRRGGRRLGARLIRSLLSRVLAEL 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1064 AARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAH-RELQGRHEQLQAQRANVEAQEVAL 1142
Cdd:COG3447 529 GAVELLLALIADLTEVALGAEALERLLERLLLALLGLGLAVAALLATLGLLLALLaALALSGAAALLALGAALLLAAAIL 608
|
330 340
....*....|....*....|....*....
gi 755563857 1143 LAERERLMQDGHRQRGLEEELRRLQNEHE 1171
Cdd:COG3447 609 GLAAALLALLRLLGERARLLETRRLVGAL 637
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
984-1292 |
3.07e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.71 E-value: 3.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 984 RLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEksmmeMQGQElhrKLGVLEEEVR 1063
Cdd:COG3096 286 RALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTA-----LRQQE---KIERYQEDLE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1064 AARRAQEEtrgQQQALLRDHEALVQLQ-RRQETELEgllvrHRDLKANMRALELAHRELQGRHEQL-QAQRANVEAQEVA 1141
Cdd:COG3096 358 ELTERLEE---QEEVVEEAAEQLAEAEaRLEAAEEE-----VDSLKSQLADYQQALDVQQTRAIQYqQAVQALEKARALC 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1142 LLAE-------------RERLMQDGHRQRGLEEELRRLQ---NEHERAQMLL----AEVSRERG-----ELQGERGELRS 1196
Cdd:COG3096 430 GLPDltpenaedylaafRAKEQQATEEVLELEQKLSVADaarRQFEKAYELVckiaGEVERSQAwqtarELLRRYRSQQA 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1197 RLARLELERAQLEIQSQQLRESNQqldlsACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLH 1276
Cdd:COG3096 510 LAQRLQQLRAQLAELEQRLRQQQN-----AERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR 584
|
330
....*....|....*.
gi 755563857 1277 REqreyLDQLNALRRE 1292
Cdd:COG3096 585 QQ----LEQLRARIKE 596
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
734-1229 |
3.21e-04 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 45.62 E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 734 ALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEAL-CLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAA 812
Cdd:COG3899 746 ALLLELAEALYLAGRFEEAEALLERALAARALAALaALRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLGD 825
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 813 SREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDR 892
Cdd:COG3899 826 RRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALA 905
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 893 LEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGAR 972
Cdd:COG3899 906 AAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAA 985
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 973 AGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELH 1052
Cdd:COG3899 986 AAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAA 1065
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1053 RKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQR 1132
Cdd:COG3899 1066 AALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALA 1145
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1133 ANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQS 1212
Cdd:COG3899 1146 LAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAAALLLL 1225
|
490
....*....|....*..
gi 755563857 1213 QQLRESNQQLDLSACRL 1229
Cdd:COG3899 1226 LLLAALALAAALLALRL 1242
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1148-1309 |
3.26e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1148 RLMQDGHRQRGLEEELRRLQNEheraqmlLAEVSRERGELQGERGELRSRLARLELERAQLEiqsQQLRESNQQL----- 1222
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDE-------LAALEARLEAAKTELEDLEKEIKRLELEIEEVE---ARIKKYEEQLgnvrn 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1223 --DLSAcrLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKI 1300
Cdd:COG1579 88 nkEYEA--LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAER 165
|
....*....
gi 755563857 1301 MDQYRVLEP 1309
Cdd:COG1579 166 EELAAKIPP 174
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
620-1183 |
3.61e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.44 E-value: 3.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 620 EVQELLGETGSreapqgELVHKAQVLKQESPKCRPRSAELT-LREPLKDQKALDRELElsKQQKETGRHEQRPKGLESKL 698
Cdd:PRK03918 190 NIEELIKEKEK------ELEEVLREINEISSELPELREELEkLEKEVKELEELKEEIE--ELEKELESLEGSKRKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 699 gpqkpQQTSEGVPDawSREEPTPGETLVSAIPEEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQAR 778
Cdd:PRK03918 262 -----RELEERIEE--LKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 779 RTEAEAHQEAEAQAREQARLREAVDTASLELEAASREREALAEALAAAGRERRQWErdgpRLRAQVEAAEQQVQALESQV 858
Cdd:PRK03918 335 EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLE----KELEELEKAKEEIEEEISKI 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 859 RCHLEEAEREHAEKQALREELEKAVLR----GQELGDrlEHLQEELEQAALERQKF---LQEQENQHQRYRHLEQRLEAE 931
Cdd:PRK03918 411 TARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTE--EHRKELLEEYTAELKRIekeLKEIEEKERKLRKELRELEKV 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 932 LqaastSKEEALMELKARALQLEEELIQLRQYPVDlatGARAGPRTVETQNGRLI-----------EVERNNAtLVAEKA 1000
Cdd:PRK03918 489 L-----KKESELIKLKELAEQLKELEEKLKKYNLE---ELEKKAEEYEKLKEKLIklkgeikslkkELEKLEE-LKKKLA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1001 ALQGQLQHLEGQLGSLQGRAQELLLQSqrAQEHSSRLQ----AEKSMMEMQG--QELHRKLGVLEEEVRAARRAQEETRG 1074
Cdd:PRK03918 560 ELEKKLDELEEELAELLKELEELGFES--VEELEERLKelepFYNEYLELKDaeKELEREEKELKKLEEELDKAFEELAE 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1075 QQQALLRDHEALVQLQRRQETElegllvRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGH 1154
Cdd:PRK03918 638 TEKRLEELRKELEELEKKYSEE------EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK 711
|
570 580
....*....|....*....|....*....
gi 755563857 1155 RQRGLEEELRRLQNEHERAQMLLAEVSRE 1183
Cdd:PRK03918 712 ELEKLEKALERVEELREKVKKYKALLKER 740
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
264-468 |
3.65e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.82 E-value: 3.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 264 QLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQ-AKRAELYREEAEALRERAGRLPRL----- 337
Cdd:COG3883 31 ELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEiEERREELGERARALYRSGGSVSYLdvllg 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 338 ----QEELRRCREKLQAAEVFKGQLEEERVLSEALEASKVLLEEQLEVARERSARLHETQREnllLRTRLGEAHADLDSL 413
Cdd:COG3883 111 sesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE---LEAQQAEQEALLAQL 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 755563857 414 RHQLEQLVEENVELELELQRSLEPPPGSPGEASLPGAAPSLQDEVREAEAGRLRA 468
Cdd:COG3883 188 SAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
264-446 |
3.80e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 3.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 264 QLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALsaQAKRAELYREEAEALRE--RAGRLPRLQ--- 338
Cdd:COG4942 49 EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL--RAELEAQKEELAELLRAlyRLGRQPPLAlll 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 339 ------EELRR-------CREKLQAAEVFKGQLEEERVLSEALEASKVLLEEQLEVARERSARL--HETQRENLL--LRT 401
Cdd:COG4942 127 spedflDAVRRlqylkylAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALeaLKAERQKLLarLEK 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 755563857 402 RLGEAHADLDSLRHQLEQLVEENVELELELQRSLEPPPGSPGEAS 446
Cdd:COG4942 207 ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
|
|
| hsdR |
PRK11448 |
type I restriction enzyme EcoKI subunit R; Provisional |
239-379 |
3.88e-04 |
|
type I restriction enzyme EcoKI subunit R; Provisional
Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 45.33 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 239 EPAHLLLPEAPANASAEgvshhlalqltnAKAQLRRLRQEVEEKAEqlldsqaEVQGLEAEIRRLRQETQALSAQAKRAE 318
Cdd:PRK11448 130 KPGPFVPPEDPENLLHA------------LQQEVLTLKQQLELQAR-------EKAQSQALAEAQQQELVALEGLAAELE 190
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755563857 319 LYREEAEA----LRERAGRLPRlQEELRRCREKLQAAEVFKgqleeervLSEALeaSKVLLEEQL 379
Cdd:PRK11448 191 EKQQELEAqleqLQEKAAETSQ-ERKQKRKEITDQAAKRLE--------LSEEE--TRILIDQQL 244
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1005-1149 |
3.90e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 3.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1005 QLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQ-------- 1076
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnke 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755563857 1077 -QALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQR----ANVEAQEVALLAERERL 1149
Cdd:COG1579 91 yEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELdeelAELEAELEELEAEREEL 168
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
253-350 |
3.99e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.85 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 253 SAEGVSHHLALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAG 332
Cdd:COG2433 396 EAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDREISRLDREIE 475
|
90
....*....|....*...
gi 755563857 333 RLPRLQEELRRCREKLQA 350
Cdd:COG2433 476 RLERELEEERERIEELKR 493
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
269-419 |
4.07e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 4.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 269 KAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAGRLPRLQEELRRCREKL 348
Cdd:PRK03918 230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL 309
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755563857 349 QAAEVFKGQLEEERvlsEALEASKVLLEEQLEVARERSARLHETQRENLLLRTRLgEAHADLDSLRHQLEQ 419
Cdd:PRK03918 310 REIEKRLSRLEEEI---NGIEERIKELEEKEERLEELKKKLKELEKRLEELEERH-ELYEEAKAKKEELER 376
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
871-1078 |
4.09e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.44 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 871 EKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLeAELQAASTSKEEALMELkARA 950
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEI-AEAEAEIEERREELGER-ARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 951 LQLEE------ELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELL 1024
Cdd:COG3883 95 LYRSGgsvsylDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 755563857 1025 LQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQA 1078
Cdd:COG3883 175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAA 228
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
839-1157 |
4.68e-04 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 44.29 E-value: 4.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 839 RLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELgdRLEHLQEELEQAALERQKFLQEQENQH 918
Cdd:pfam19220 59 QERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEEL--RIELRDKTAQAEALERQLAAETEQNRA 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 919 qryrhleqrLEAELQAASTSKEEAlmelKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAE 998
Cdd:pfam19220 137 ---------LEEENKALREEAQAA----EKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQ 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 999 KAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEhssRLQAEKSMMEMQGQELHRKLGVLE--------------EEVRA 1064
Cdd:pfam19220 204 LDATRARLRALEGQLAAEQAERERAEAQLEEAVE---AHRAERASLRMKLEALTARAAATEqllaearnqlrdrdEAIRA 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1065 ARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRH-----------RDLKANMRALELAHRELQGRHEQLQAQRA 1133
Cdd:pfam19220 281 AERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARaeleeraemltKALAAKDAALERAEERIASLSDRIAELTK 360
|
330 340
....*....|....*....|....
gi 755563857 1134 NVEAQEVALLAERERLMQDGHRQR 1157
Cdd:pfam19220 361 RFEVERAALEQANRRLKEELQRER 384
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
741-1264 |
5.57e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.78 E-value: 5.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 741 QLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQarrteaeahqeaeaQAREQARLREAVDTaslELEAASREREALA 820
Cdd:pfam01576 458 KLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ--------------LEDERNSLQEQLEE---EEEAKRNVERQLS 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 821 EALAAAGRERRQWERDGprlrAQVEAAEQQVQALESQvrchLEEAEREHAEKQALREELEKAVLR-GQELGDRLEHLQEE 899
Cdd:pfam01576 521 TLQAQLSDMKKKLEEDA----GTLEALEEGKKRLQRE----LEALTQQLEEKAAAYDKLEKTKNRlQQELDDLLVDLDHQ 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 900 ------LEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAAST---SKEEALMELKARALQLEEELIQLRQYPVDLATG 970
Cdd:pfam01576 593 rqlvsnLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETralSLARALEEALEAKEELERTNKQLRAEMEDLVSS 672
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 971 ARAGPRTVEtqngrliEVERNNATLVAEKAALQGQLQHLEGQLGSLQgraqelllqsqraqehSSRLQAEKSMMEMQGQe 1050
Cdd:pfam01576 673 KDDVGKNVH-------ELERSKRALEQQVEEMKTQLEELEDELQATE----------------DAKLRLEVNMQALKAQ- 728
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1051 lhrklgvLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEG----LLVRHRDLKANMRALELAHRELQGRHE 1126
Cdd:pfam01576 729 -------FERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAakkkLELDLKELEAQIDAANKGREEAVKQLK 801
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1127 QLQAQRANVEAQEVALLAERERLM----QDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLE 1202
Cdd:pfam01576 802 KLQAQMKDLQRELEEARASRDEILaqskESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQ 881
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755563857 1203 LERAQLEIQSQQLRESNQQLDLSA-------CRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENREL 1264
Cdd:pfam01576 882 DEKRRLEARIAQLEEELEEEQSNTellndrlRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKEL 950
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
203-352 |
6.12e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 6.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 203 AEELEMQLRSLTGMMSRLARERDLGAQRLAELLLEREPAHLLLPEAPANAsaegvshhlalQLTNAKAQLRRLRQEVEEK 282
Cdd:COG3206 214 AKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSP-----------VIQQLRAQLAELEAELAEL 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 283 AEQLLDSQAEVQGLEAEIRRLRQ-------------ETQALSAQAKRAELyREEAEALRERAGRLPRLQEELRRCREKLQ 349
Cdd:COG3206 283 SARYTPNHPDVIALRAQIAALRAqlqqeaqrilaslEAELEALQAREASL-QAQLAQLEARLAELPELEAELRRLEREVE 361
|
...
gi 755563857 350 AAE 352
Cdd:COG3206 362 VAR 364
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1105-1308 |
6.93e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 6.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1105 RDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQdghrqrgLEEELRRLQNEHERAQMLLAEVSRER 1184
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQ-------LEEELEELNEQLQAAQAELAQAQEEL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1185 GELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLtqlrsaqEEENRQLLAEVQALSRENREL 1264
Cdd:COG4372 104 ESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKEL-------EEQLESLQEELAALEQELQAL 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 755563857 1265 LERSLESR-DHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLE 1308
Cdd:COG4372 177 SEAEAEQAlDELLKEANRNAEKEEELAEAEKLIESLPRELAEELL 221
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
829-960 |
6.99e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.93 E-value: 6.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 829 ERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLqEELEQAALERQ 908
Cdd:PRK12705 33 KEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKL-DNLENQLEERE 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 755563857 909 KFLQEQENQhqrYRHLEQRLEAELQAASTSKEEALMELKARALQ--LEEELIQL 960
Cdd:PRK12705 112 KALSARELE---LEELEKQLDNELYRVAGLTPEQARKLLLKLLDaeLEEEKAQR 162
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
897-1156 |
7.56e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 44.25 E-value: 7.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 897 QEELEQAALERQkfLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQyPVDLATGARAGPR 976
Cdd:pfam05667 223 EEEWNSQGLASR--LTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELLSSFSG-SSTTDTGLTKGSR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 977 TVETQNGRLIEVERNNATLVAEKAALQGQLQ-HLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKL 1055
Cdd:pfam05667 300 FTHTEKLQFTNEAPAATSSPPTKVETEEELQqQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQN 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1056 GVLEEEVRAARRAQE---ETRGQQQALLRDHEA----LVQLQRRQETELEGLLVRHRDLK--ANMRALELAHR--ELQGR 1124
Cdd:pfam05667 380 EELEKQYKVKKKTLDllpDAEENIAKLQALVDAsaqrLVELAGQWEKHRVPLIEEYRALKeaKSNKEDESQRKleEIKEL 459
|
250 260 270
....*....|....*....|....*....|....*..
gi 755563857 1125 HEQLQ-----AQRAnvEAQEVALLAERERLMQDGHRQ 1156
Cdd:pfam05667 460 REKIKevaeeAKQK--EELYKQLVAEYERLPKDVSRS 494
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
828-1173 |
1.02e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDGPRLRAQVEAAEQQVQALESQVrchleeaerehaekQALREEL-EKAVLRGQELGDRLEHLQEELEQaALE 906
Cdd:PRK04863 844 RRRVELERALADHESQEQQQRSQLEQAKEGL--------------SALNRLLpRLNLLADETLADRVEEIREQLDE-AEE 908
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 907 RQKFLQeqenQHQRYRHLEQRLEAELQaastSKEEALMELKARALQLEEELIQLRQypvdlatGARAGPRTVETQNGRLI 986
Cdd:PRK04863 909 AKRFVQ----QHGNALAQLEPIVSVLQ----SDPEQFEQLKQDYQQAQQTQRDAKQ-------QAFALTEVVQRRAHFSY 973
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 987 EverNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQ-RAQEHSSRLQAEKSMMEMQGQELHRKLGVLEE-EVRA 1064
Cdd:PRK04863 974 E---DAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQaQLAQYNQVLASLKSSYDAKRQMLQELKQELQDlGVPA 1050
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1065 ARRAQEETRGQQQALlrdHEALVQlQRRQETELEGLLVRhrdLKANMRALELAHRELQgrhEQLQAQRANVEAQEVALLA 1144
Cdd:PRK04863 1051 DSGAEERARARRDEL---HARLSA-NRSRRNQLEKQLTF---CEAEMDNLTKKLRKLE---RDYHEMREQVVNAKAGWCA 1120
|
330 340
....*....|....*....|....*....
gi 755563857 1145 ERERLMQDGHRQRGLEEELRRLQNEHERA 1173
Cdd:PRK04863 1121 VLRLVKDNGVERRLHRRELAYLSADELRS 1149
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
620-1037 |
1.05e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 620 EVQELLGETGSREAPQGELVH---------KAQVLKQESPKCRPRSAELTLREPLKDQKALDRELELSKQ-----QKETG 685
Cdd:TIGR00618 408 EQATIDTRTSAFRDLQGQLAHakkqqelqqRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTkeqihLQETR 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 686 RHEQRPKGLESKLGPQKP--QQTSEGVPDAWSREEPTPGETLVSAIPEE---------------QALRDEVAQLRREVAG 748
Cdd:TIGR00618 488 KKAVVLARLLELQEEPCPlcGSCIHPNPARQDIDNPGPLTRRMQRGEQTyaqletseedvyhqlTSERKQRASLKEQMQE 567
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 749 LEVKLQAQAQRLEARSAEA----------LCLSEELAQARRTEAEAHQEAEAQAREQARLRE--AVDTASLELEAASRER 816
Cdd:TIGR00618 568 IQQSFSILTQCDNRSKEDIpnlqnitvrlQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDvrLHLQQCSQELALKLTA 647
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 817 EALAEALAAAGRERRQWER---DGPRLRAQVEAAEQQVQALESQVRCHLE----------EAEREHAEKQALREELEKAV 883
Cdd:TIGR00618 648 LHALQLTLTQERVREHALSirvLPKELLASRQLALQKMQSEKEQLTYWKEmlaqcqtllrELETHIEEYDREFNEIENAS 727
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 884 L-RGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYrhlEQRLEAELQAAsTSKEEALMELKARALQLEEELIQLRQ 962
Cdd:TIGR00618 728 SsLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNN---NEEVTAALQTG-AELSHLAAEIQFFNRLREEDTHLLKT 803
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755563857 963 YPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRL 1037
Cdd:TIGR00618 804 LEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| FtsB |
COG2919 |
Cell division protein FtsB [Cell cycle control, cell division, chromosome partitioning]; |
271-320 |
1.08e-03 |
|
Cell division protein FtsB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442163 [Multi-domain] Cd Length: 96 Bit Score: 39.86 E-value: 1.08e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 755563857 271 QLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAkRAELY 320
Cdd:COG2919 30 AYRELRQEIAELEAENAKLKARNAELEAEVADLKDGPDYIEERA-REELG 78
|
|
| CHASE3 |
COG5278 |
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms]; |
732-1167 |
1.13e-03 |
|
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 43.36 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 732 EQALRDEVAQLRREVAGlEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEA 811
Cdd:COG5278 85 RAEIDELLAELRSLTAD-NPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLAL 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 812 ASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGD 891
Cdd:COG5278 164 ALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALA 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 892 RLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGA 971
Cdd:COG5278 244 LLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAA 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 972 RAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQEL 1051
Cdd:COG5278 324 ALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAA 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1052 HRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQ 1131
Cdd:COG5278 404 AEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAA 483
|
410 420 430
....*....|....*....|....*....|....*.
gi 755563857 1132 RANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQ 1167
Cdd:COG5278 484 LAEAEAAAALAAAAALSLALALAALLLAAAEAALAA 519
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
274-405 |
1.13e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 43.53 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 274 RLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSaqAKRAELYREEAEALREragRLPRLQEELRRCREKLQAAEV 353
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEAS--FERLAELRDELAELEE---ELEALKARWEAEKELIEEIQE 475
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755563857 354 FKGQLEEERVLSEALEASKVLLEEQLEVARERS---------------------ARLHETQRENLL-LRTRLGE 405
Cdd:COG0542 476 LKEELEQRYGKIPELEKELAELEEELAELAPLLreevteediaevvsrwtgipvGKLLEGEREKLLnLEEELHE 549
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
270-419 |
1.17e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 270 AQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERA-GRLPRL--QEELRRCRE 346
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYeEQLGNVrnNKEYEALQK 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755563857 347 KLQAAEVFKGQLEEE-RVLSEALEASKVLLEEQLEVARERSARLHETQREnllLRTRLGEAHADLDSLRHQLEQ 419
Cdd:COG1579 97 EIESLKRRISDLEDEiLELMERIEELEEELAELEAELAELEAELEEKKAE---LDEELAELEAELEELEAEREE 167
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1126-1298 |
1.25e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.47 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1126 EQLQAQRANVEAQEVALLA--ERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLeL 1203
Cdd:COG3206 182 EQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL-L 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1204 ERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREYL 1283
Cdd:COG3206 261 QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLE 340
|
170
....*....|....*
gi 755563857 1284 DQLNALRREKQKLVE 1298
Cdd:COG3206 341 ARLAELPELEAELRR 355
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
874-1260 |
1.35e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 43.36 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 874 ALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAA----STSKEEALMELKAR 949
Cdd:pfam15964 318 SVRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQqekrAQEKEALRKEMKKE 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 950 ALQLEEELIQLRQYPVDLatgaragprtvetqNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQR 1029
Cdd:pfam15964 398 REELGATMLALSQNVAQL--------------EAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKM 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1030 AQEHSSRLQAEKSM-----MEMQGQELhRKLGV--------LEEEVRAARRAQEETRGQQQaLLRDHEALVQLQRRQETE 1096
Cdd:pfam15964 464 KKDEAEKEHREYRTktgrqLEIKDQEI-EKLGLelseskqrLEQAQQDAARAREECLKLTE-LLGESEHQLHLTRLEKES 541
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1097 LEGLLvrHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMqdghrqRGLEEEL----RRLQNEHER 1172
Cdd:pfam15964 542 IQQSF--SNEAKAQALQAQQREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFI------AKLKEECctlaKKLEEITQK 613
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1173 AQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDlSACRLTTQceLLTQLRSAQeeenRQLLA 1252
Cdd:pfam15964 614 SRSEVEQLSQEKEYLQDRLEKLQKRNEELEEQCVQHGRMHERMKQRLRQLD-KHCQATAQ--QLVQLLSKQ----NQLFK 686
|
....*...
gi 755563857 1253 EVQALSRE 1260
Cdd:pfam15964 687 ERQNLTEE 694
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
247-963 |
1.38e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 247 EAPANASAEGVSHHLALQLTNAKAQLRRLrqEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEA 326
Cdd:pfam02463 298 LKSELLKLERRKVDDEEKLKESEKEKKKA--EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEEL 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 327 LRERAGRLPRLQEELRRCREKLQAaevfkgQLEEERVLSEALEASKVLLEEQLEVARERSARLHETQRENLLLRTRLGEA 406
Cdd:pfam02463 376 LAKKKLESERLSSAAKLKEEELEL------KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 407 HADLDSLRHQLEQLVEENVELELELQrslepppgspgEASLPGAAPSLQDEVREAEAGRLRAVERENRELRGQLQMLQAQ 486
Cdd:pfam02463 450 KEELEKQELKLLKDELELKKSEDLLK-----------ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKD 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 487 LGSQHPLLEEQRENSRQPPVPNRDPAT----PSALHHSPQSPACQIGGEGSESLDLPSPASYSDITRSPKCSQAPDSHPE 562
Cdd:pfam02463 519 GVGGRIISAHGRLGDLGVAVENYKVAIstavIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLE 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 563 LESPLQMVSQDPQT----SDQALQESDPTVETHQCLEKSGHRVPLQSPIVWDPPQGPEVRIEVQELLGETGSREAPQGEL 638
Cdd:pfam02463 599 IDPILNLAQLDKATleadEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEI 678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 639 VHKAQVLKQESPKCRPRSAELTLREPLKDQKALDRELELSKQQKETGRH--EQRPKGLESKLGPQKPQQTSEgVPDAWSR 716
Cdd:pfam02463 679 QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVqeAQDKINEELKLLKQKIDEEEE-EEEKSRL 757
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 717 EEPTPGETLVSAIPEEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALcLSEELAQARRTEAEAHQEAEAQAREQA 796
Cdd:pfam02463 758 KKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE-LKEEAELLEEEQLLIEQEEKIKEEELE 836
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 797 RLREAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRchlEEAEREHAEKQALR 876
Cdd:pfam02463 837 ELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEK---KELEEESQKLNLLE 913
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 877 EELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALME----------L 946
Cdd:pfam02463 914 EKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEfeekeerynkD 993
|
730
....*....|....*..
gi 755563857 947 KARALQLEEELIQLRQY 963
Cdd:pfam02463 994 ELEKERLEEEKKKLIRA 1010
|
|
| Mating_C |
pfam12737 |
C-terminal domain of homeodomain 1; Mating in fungi is controlled by the loci that determine ... |
468-566 |
1.54e-03 |
|
C-terminal domain of homeodomain 1; Mating in fungi is controlled by the loci that determine the mating type of an individual, and only individuals with differing mating types can mate. Basidiomycete fungi have evolved a unique mating system, termed tetrapolar or bifactorial incompatibility, in which mating type is determined by two unlinked loci; compatibility at both loci is required for mating to occur. The multi-allelic tetrapolar mating system is considered to be a novel innovation that could have only evolved once, and is thus unique to the mushroom fungi. This domain is C-terminal to the homeodomain transcription factor region.
Pssm-ID: 372279 [Multi-domain] Cd Length: 412 Bit Score: 42.67 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 468 AVERENRELRGQLQMLQAQLgsqhpLLEEQRENSRQP-PVPNRDPATPSALHHSPQSPACQIGGEGsESLDLP---SPAS 543
Cdd:pfam12737 34 AVKDMTPDLKEQLKDEKKRK-----RQAERSMRDALAyPSPERSPASSPERNLSPQVDVCQLTIRQ-NNLNLKrrsSSSS 107
|
90 100
....*....|....*....|...
gi 755563857 544 YSDITRSPKCSQAPDSHPELESP 566
Cdd:pfam12737 108 DVDSSNAERCHKRPRLDSPSSSS 130
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
1032-1303 |
1.61e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 43.20 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1032 EHSSRLQAEKSMMEMQGQELHRklgvLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLlvrhrdlKANM 1111
Cdd:pfam07111 56 EGSQALSQQAELISRQLQELRR----LEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGL-------RAAL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1112 RALELAHRELQ-GRHEQLQA-QRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRE----RG 1185
Cdd:pfam07111 125 AGAEMVRKNLEeGSQRELEEiQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEaellRK 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1186 ELQGERGELRSRLARLE--------------------LERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEE 1245
Cdd:pfam07111 205 QLSKTQEELEAQVTLVEslrkyvgeqvppevhsqtweLERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEE 284
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755563857 1246 ENRQLLAEVQAL----SRENRELLERSLES----RDHLHREQREYLDQLNALRREKQKLVEKIMDQ 1303
Cdd:pfam07111 285 ELTRKIQPSDSLepefPKKCRSLLNRWREKvfalMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQ 350
|
|
| SerS |
COG0172 |
Seryl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Seryl-tRNA synthetase ... |
1079-1177 |
1.74e-03 |
|
Seryl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Seryl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439942 [Multi-domain] Cd Length: 421 Bit Score: 42.68 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1079 LLRDHEALVQlqrrqetelEGLLVRHRDLKAN-MRALELAHRELQGRHEQLQAQRaNVEAQEVALL----AERERLMQD- 1152
Cdd:COG0172 6 LIRENPEAVK---------EALAKRGFDLDVDeLLELDEERRELQTEVEELRAER-NALSKEIGKAkkkgEEAEALIAEv 75
|
90 100
....*....|....*....|....*...
gi 755563857 1153 ---GHRQRGLEEELRRLQNEHERAQMLL 1177
Cdd:COG0172 76 kelKEEIKELEEELKELEEELDELLLSI 103
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
828-1182 |
1.80e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDgprlRAQVEAAEQQVQALESQVRCHLeeaerehaekQALREELEKAVLRGQE-LGDRLEHLQEELEQaALE 906
Cdd:COG3096 843 QRRSELERE----LAQHRAQEQQLRQQLDQLKEQL----------QLLNKLLPQANLLADEtLADRLEELREELDA-AQE 907
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 907 RQKFLQeqenQHQRYRHLEQRLEAELQAASTSKEealmELKARALQLEEELIQLRQYPVDLA-TGARAGPRTVETQNGRL 985
Cdd:COG3096 908 AQAFIQ----QHGKALAQLEPLVAVLQSDPEQFE----QLQADYLQAKEQQRRLKQQIFALSeVVQRRPHFSYEDAVGLL 979
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 986 IEvernNATLVaekAALQGQLQHLEGQlgslQGRAQELLLQSQ-RAQEHSSRLQAEKSMMEMQGQELHRKLGVLEE-EVR 1063
Cdd:COG3096 980 GE----NSDLN---EKLRARLEQAEEA----RREAREQLRQAQaQYSQYNQVLASLKSSRDAKQQTLQELEQELEElGVQ 1048
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1064 AARRAQEETRGQQQALlrdHEALVQL-QRRQETElEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRA--------- 1133
Cdd:COG3096 1049 ADAEAEERARIRRDEL---HEELSQNrSRRSQLE-KQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKAgwcavlrla 1124
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 755563857 1134 ---NVEAQevalLAERERLMQDGHRQRG-LEEELRRLQ-----NEHERAQMLLAEVSR 1182
Cdd:COG3096 1125 rdnDVERR----LHRRELAYLSADELRSmSDKALGALRlavadNEHLRDALRLSEDPR 1178
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
269-419 |
1.82e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.80 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 269 KAQLRRLRQEVEEKAEQL----------------LDSQAEVQG--------LEAEIRRLRQETQALSAQAKRAELYREEA 324
Cdd:pfam17380 295 KMEQERLRQEKEEKAREVerrrkleeaekarqaeMDRQAAIYAeqermameRERELERIRQEERKRELERIRQEEIAMEI 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 325 EALRERAGRLPRLQEELRRCREKLQAAEVFKGQLEEERVLSEALEASKVLLEEQLEVARERSARLHETQRENLLLRTRLG 404
Cdd:pfam17380 375 SRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLE 454
|
170
....*....|....*..
gi 755563857 405 EA--HADLDSLRHQLEQ 419
Cdd:pfam17380 455 EQerQQQVERLRQQEEE 471
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
828-1223 |
1.84e-03 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 42.87 E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDGPRLRAQVEAAEQQVQALESqvrchleEAEREHAEKQALREELekavlrgQELGDRLE---HLQEELeqaa 904
Cdd:PRK10246 537 KEVKKLGEEGAALRGQLDALTKQLQRDES-------EAQSLRQEEQALTQQW-------QAVCASLNitlQPQDDI---- 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 905 lerQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALME--LKARALQLEEeliQLRQYPVDLATgaragprtvetqn 982
Cdd:PRK10246 599 ---QPWLDAQEEHERQLRLLSQRHELQGQIAAHNQQIIQYQqqIEQRQQQLLT---ALAGYALTLPQ------------- 659
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 983 grlievERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELL-LQSQRAQEHSSRLQAEKSMMEmQGQELHRKLGVLEee 1061
Cdd:PRK10246 660 ------EDEEASWLATRQQEAQSWQQRQNELTALQNRIQQLTpLLETLPQSDDLPHSEETVALD-NWRQVHEQCLSLH-- 730
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1062 vraarrAQEETRGQQ--QALLRDHEALVQLqrrqETELEGllVRHRDLKANMRAleLAHRELQGRHEQLQAQRANVEAQE 1139
Cdd:PRK10246 731 ------SQLQTLQQQdvLEAQRLQKAQAQF----DTALQA--SVFDDQQAFLAA--LLDEETLTQLEQLKQNLENQRQQA 796
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1140 VALLAERERLMQDGHRQR--GLEEELRRLQNEHERAQmlLAEVSRERGELQgerGELRSRLARLELERAQLEIQSQQLRE 1217
Cdd:PRK10246 797 QTLVTQTAQALAQHQQHRpdGLDLTVTVEQIQQELAQ--LAQQLRENTTRQ---GEIRQQLKQDADNRQQQQALMQQIAQ 871
|
....*.
gi 755563857 1218 SNQQLD 1223
Cdd:PRK10246 872 ATQQVE 877
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
793-1292 |
2.24e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 42.92 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 793 REQARLREAVDTASLELEAASREREALAEALAAAGRERRQWERDG-PRLRAQVEAAEQQVQALESQVRCHLEEAEREHAE 871
Cdd:COG3899 742 EYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGnPPASARAYANLGLLLLGDYEEAYEFGELALALAE 821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 872 KQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARAL 951
Cdd:COG3899 822 RLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAA 901
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 952 QLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQ 1031
Cdd:COG3899 902 AALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAA 981
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1032 EHSSRLQAeksmmemQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANM 1111
Cdd:COG3899 982 AAAAAAAA-------ALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAA 1054
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1112 RALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGER 1191
Cdd:COG3899 1055 AAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAA 1134
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1192 GELRSRLARLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLES 1271
Cdd:COG3899 1135 LLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALAL 1214
|
490 500
....*....|....*....|.
gi 755563857 1272 RDHLHREQREYLDQLNALRRE 1292
Cdd:COG3899 1215 LALEAAALLLLLLLAALALAA 1235
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
273-419 |
2.43e-03 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 42.03 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 273 RRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALREragRLPRLQEELRRCREKLQAAE 352
Cdd:pfam00529 54 TDYQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQA---AVKAAQAQLAQAQIDLARRR 130
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755563857 353 VF-------KGQLEEERVLSEALEASKVLLEEQLEVARERSARLHETQREnlLLRTRLGEAHADLDSLRHQLEQ 419
Cdd:pfam00529 131 VLapiggisRESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQA--EVRSELSGAQLQIAEAEAELKL 202
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
733-938 |
2.64e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 733 QALRDEVAQLRREVAGLEVKLQA--QAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:COG3206 178 EFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALP 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERR------QWERDGP---RLRAQVEAAEQQVQALESQVrchLEEAEREHAEKQALREELEK 881
Cdd:COG3206 258 ELLQSPVIQQLRAQLAELEAElaelsaRYTPNHPdviALRAQIAALRAQLQQEAQRI---LASLEAELEALQAREASLQA 334
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 755563857 882 AVlrgQELGDRLEHLQE-ELEQAALERqkflqEQENQHQRYRHLEQRL-EAELQAASTS 938
Cdd:COG3206 335 QL---AQLEARLAELPElEAELRRLER-----EVEVARELYESLLQRLeEARLAEALTV 385
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
998-1226 |
2.72e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 998 EKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKsmmemqgQELHRKLGVLEEEVRAARRAQEetrgQQQ 1077
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAEL-------EALQAEIDKLQAEIAEAEAEIE----ERR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1078 ALLRDHEALVQLQRRQETELEGLLVRH--RDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQdghR 1155
Cdd:COG3883 86 EELGERARALYRSGGSVSYLDVLLGSEsfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEA---L 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755563857 1156 QRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSA 1226
Cdd:COG3883 163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
840-1020 |
2.77e-03 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 41.67 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 840 LRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQElgdRLEHLQEELEQAALERQKFLQEQENQHQ 919
Cdd:pfam09787 73 LRTELQELEAQQQEEAESSREQLQELEEQLATERSARREAEAELERLQE---ELRYLEEELRRSKATLQSRIKDREAEIE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 920 RyrhleQRLEAELQAASTSKEEalmELKARALQLEEELIQlRQYPVDlatgaragprtvetqngrlievernnaTLVAEK 999
Cdd:pfam09787 150 K-----LRNQLTSKSQSSSSQS---ELENRLHQLTETLIQ-KQTMLE---------------------------ALSTEK 193
|
170 180
....*....|....*....|.
gi 755563857 1000 AALQGQLQHLEGQLGSLQGRA 1020
Cdd:pfam09787 194 NSLVLQLERMEQQIKELQGEG 214
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
1103-1303 |
3.03e-03 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 41.98 E-value: 3.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1103 RHRDLKANMRALELAHRELQGRHEQLQAQ-----RANVEAQE-VALLAERERLMQDGHRQRGLEEELRRLQNEHERAQML 1176
Cdd:COG0497 166 AWRALKKELEELRADEAERARELDLLRFQleeleAAALQPGEeEELEEERRRLSNAEKLREALQEALEALSGGEGGALDL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1177 LAEVSRERGELQGERGELRSRLARleLERAQLEIQ--SQQLRESNQQLDLSACRLTTQCELLTQLRSAQ-------EEen 1247
Cdd:COG0497 246 LGQALRALERLAEYDPSLAELAER--LESALIELEeaASELRRYLDSLEFDPERLEEVEERLALLRRLArkygvtvEE-- 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755563857 1248 rqlLAEVQALSRENRELLERSLESRDHLHRE----QREYLD---QLNALRREK-QKLVEKIMDQ 1303
Cdd:COG0497 322 ---LLAYAEELRAELAELENSDERLEELEAElaeaEAELLEaaeKLSAARKKAaKKLEKAVTAE 382
|
|
| CHASE3 |
COG5278 |
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms]; |
835-1226 |
3.09e-03 |
|
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 42.20 E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 835 RDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQ 914
Cdd:COG5278 131 RAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLE 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 915 ENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGARAGPRTVETQNGRLIEVERNNAT 994
Cdd:COG5278 211 AELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALE 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 995 LVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRG 1074
Cdd:COG5278 291 LAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAA 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1075 QQQALLRDHEALVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGH 1154
Cdd:COG5278 371 AALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELA 450
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755563857 1155 RQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQLEIQSQQLRESNQQLDLSA 1226
Cdd:COG5278 451 EAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALA 522
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
264-352 |
3.23e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.99 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 264 QLTNAKAQLRRLRQEVEE-KAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAK----RAELYREEAEALRERAGRLPRLQ 338
Cdd:COG0542 412 ELDELERRLEQLEIEKEAlKKEQDEASFERLAELRDELAELEEELEALKARWEaekeLIEEIQELKEELEQRYGKIPELE 491
|
90
....*....|....
gi 755563857 339 EELRRCREKLQAAE 352
Cdd:COG0542 492 KELAELEEELAELA 505
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1021-1209 |
3.88e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1021 QELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGL 1100
Cdd:COG1579 6 LRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1101 lvrhrdlkANMRALELAHRELqgrhEQLQAQRANVEAQEVALLAERERlmqdghrqrgLEEELRRLQNEHERAQmllAEV 1180
Cdd:COG1579 86 --------RNNKEYEALQKEI----ESLKRRISDLEDEILELMERIEE----------LEEELAELEAELAELE---AEL 140
|
170 180
....*....|....*....|....*....
gi 755563857 1181 SRERGELQGERGELRSRLARLELERAQLE 1209
Cdd:COG1579 141 EEKKAELDEELAELEAELEELEAEREELA 169
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
1004-1263 |
3.88e-03 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 41.59 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1004 GQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQqqalLRDH 1083
Cdd:pfam19220 20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVAR----LAKL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1084 EALVqlqRRQETELEGLLVRHRDLKANMRALE----LAHRELQGRHEQLQAQRANVEAQEvALLAERERLMQDGHRQRGL 1159
Cdd:pfam19220 96 EAAL---REAEAAKEELRIELRDKTAQAEALErqlaAETEQNRALEEENKALREEAQAAE-KALQRAEGELATARERLAL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1160 -EEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLEL----ERAQLEIQSQQLRESNQQLDLSACRLTTQCE 1234
Cdd:pfam19220 172 lEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGqlaaEQAERERAEAQLEEAVEAHRAERASLRMKLE 251
|
250 260
....*....|....*....|....*....
gi 755563857 1235 LLTqlrsAQEEENRQLLAEVQALSRENRE 1263
Cdd:pfam19220 252 ALT----ARAAATEQLLAEARNQLRDRDE 276
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
655-1077 |
3.96e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 3.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 655 RSAELTLREPLKDQKALDRELELSKQQKETGRHEQRpkGLESKLGPQKPQQTSEGVPDAWSREEPTPgETLVSAIPEEQA 734
Cdd:COG4717 84 EEKEEEYAELQEELEELEEELEELEAELEELREELE--KLEKLLQLLPLYQELEALEAELAELPERL-EELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 735 LRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALC-LSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAAS 813
Cdd:COG4717 161 LEEELEELEAELAELQEELEELLEQLSLATEEELQdLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 814 REREALAEA--------------LAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREEL 879
Cdd:COG4717 241 LEERLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEE 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 880 EKAVLRGQELGDRLE-HLQEELEQAALERQKFLQEQENQHQRYR--HLEQRLEAELQAASTSKEEALMELKARALQLEEE 956
Cdd:COG4717 321 LEELLAALGLPPDLSpEELLELLDRIEELQELLREAEELEEELQleELEQEIAALLAEAGVEDEEELRAALEQAEEYQEL 400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 957 LIQLRQYPVDLAtgARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELllqsqRAQEHSSR 1036
Cdd:COG4717 401 KEELEELEEQLE--ELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL-----EEDGELAE 473
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 755563857 1037 LQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQ 1077
Cdd:COG4717 474 LLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
254-497 |
4.55e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.86 E-value: 4.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 254 AEGVSHHLALQLTNAKAQLRRLRQEVEEKAEQLLDSQaevQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAGR 333
Cdd:COG3096 366 QEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQ---QALDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDY 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 334 LPRLQ-------EELRRCREKLQAAEVFKGQLEEERVLSEALeASKVLLEEQLEVARE--RSARLHETQRENL-LLRTRL 403
Cdd:COG3096 443 LAAFRakeqqatEEVLELEQKLSVADAARRQFEKAYELVCKI-AGEVERSQAWQTAREllRRYRSQQALAQRLqQLRAQL 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 404 GEahadldsLRHQLEQLVEENVELELELQRSlepppgspgeASLPGAAPSLQDEVREAEAGRLRAVE--RENRELRGQLQ 481
Cdd:COG3096 522 AE-------LEQRLRQQQNAERLLEEFCQRI----------GQQLDAAEELEELLAELEAQLEELEEqaAEAVEQRSELR 584
|
250
....*....|....*.
gi 755563857 482 MLQAQLGSQHPLLEEQ 497
Cdd:COG3096 585 QQLEQLRARIKELAAR 600
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1116-1280 |
4.71e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.23 E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1116 LAHRELQGRHEQLQAQRANVEAQEVALLAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAevsrERGELQGERGElr 1195
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLV----QKEEQLDARAE-- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1196 srlaRLELERAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRsaQEEENRQLLAEVQALSRENRELLERSLESRDHL 1275
Cdd:PRK12705 99 ----KLDNLENQLEEREKALSARELELEELEKQLDNELYRVAGLT--PEQARKLLLKLLDAELEEEKAQRVKKIEEEADL 172
|
....*
gi 755563857 1276 HREQR 1280
Cdd:PRK12705 173 EAERK 177
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
264-342 |
5.02e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.54 E-value: 5.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 264 QLTNAKAQLRRL---RQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALR-ERAGRLPRLQE 339
Cdd:PHA02562 307 KLKELQHSLEKLdtaIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFvDNAEELAKLQD 386
|
...
gi 755563857 340 ELR 342
Cdd:PHA02562 387 ELD 389
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
731-1107 |
5.47e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 41.38 E-value: 5.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 731 EEQALRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARLREAVDTASLELE 810
Cdd:COG3899 862 ETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAA 941
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 811 AASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELG 890
Cdd:COG3899 942 AAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLA 1021
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 891 DRLEHLQEELEQAALERQKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATG 970
Cdd:COG3899 1022 AALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAA 1101
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 971 ARAGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQE 1050
Cdd:COG3899 1102 AAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAA 1181
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 755563857 1051 LHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQLQRRQETELEGLLVRHRDL 1107
Cdd:COG3899 1182 LLAAAAAAAAAAALLAALLALAARLAALLALALLALEAAALLLLLLLAALALAAALL 1238
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
204-961 |
5.65e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 5.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 204 EELEMQLRSLTGMMSRLARERDLGAQRLAELLLEREPAHLLLPEAPANASAEGVSHHLALQ--LTNAKAQLRRLRQEVEE 281
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKekIGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 282 KAEQLLDSQAEVQGLEAEIRRLRQETQALSaqaKRAELYREEAEALRERagrLPRLQEELRRCREKLQAAEVFKGQLEEE 361
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLAEIEELE---REIEEERKRRDKLTEE---YAELKEELEDLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 362 rvLSEALEASKVLLEEQLEVARERSARLHETQRenllLRTRLGEAHADLDSLRHQLEQLVEENVELELELQRSlepppgs 441
Cdd:TIGR02169 387 --LKDYREKLEKLKREINELKRELDRLQEELQR----LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ------- 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 442 pgEASLPGAAPSLQDEVREAEAGR--LRAVERENRELRGQLQMLQAQLGSqhpLLEEQRENSRQPPVPNRD--------- 510
Cdd:TIGR02169 454 --EWKLEQLAADLSKYEQELYDLKeeYDRVEKELSKLQRELAEAEAQARA---SEERVRGGRAVEEVLKASiqgvhgtva 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 511 ----------PATPSALHHSPQSPACQIGGEGSESLDL-----PSPASYSDITR---SPKCSQAPDSHPELESPLQMVSQ 572
Cdd:TIGR02169 529 qlgsvgeryaTAIEVAAGNRLNNVVVEDDAVAKEAIELlkrrkAGRATFLPLNKmrdERRDLSILSEDGVIGFAVDLVEF 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 573 DPQTS--------DQALQESDPTVETH-----------QCLEKSG-----HRVP--LQSPIVWDPPQGPEVRIEVQELLG 626
Cdd:TIGR02169 609 DPKYEpafkyvfgDTLVVEDIEAARRLmgkyrmvtlegELFEKSGamtggSRAPrgGILFSRSEPAELQRLRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 627 EtgsREAPQGELVHKAQVLKQESPKCRPRSAELTLREplKDQKALDRELELSKQQKETGRHEQRP------------KGL 694
Cdd:TIGR02169 689 E---LSSLQSELRRIENRLDELSQELSDASRKIGEIE--KEIEQLEQEEEKLKERLEELEEDLSSleqeienvkselKEL 763
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 695 ESKLGPQkpQQTSEGVPDAWSREEPTPGEtlvSAIPEeqaLRDEVAQLRREVAGLEVKLQAQAQRLEARSAEALCLSEEL 774
Cdd:TIGR02169 764 EARIEEL--EEDLHKLEEALNDLEARLSH---SRIPE---IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 775 AQARRTEAEAHQEAEAQAREQARLREAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQAL 854
Cdd:TIGR02169 836 QELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 855 E---SQVRCHLEEAEREHAEKQALREELEKAVLRGQELGD---RLEHLQEELEqaALERQKFLQEQEnqhqrYRHLEQRL 928
Cdd:TIGR02169 916 RkrlSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDvqaELQRVEEEIR--ALEPVNMLAIQE-----YEEVLKRL 988
|
810 820 830
....*....|....*....|....*....|...
gi 755563857 929 EaELQaastSKEEALMELKARALQLEEELIQLR 961
Cdd:TIGR02169 989 D-ELK----EKRAKLEEERKAILERIEEYEKKK 1016
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
908-1324 |
6.37e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 6.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 908 QKFLQEQENQHQRYRHLEQRLEAELQAASTSKEEALMELKaralQLEEELIQLRQYPVDlATGARAGPRTVETQNGRLIE 987
Cdd:TIGR00606 576 EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE----SKEEQLSSYEDKLFD-VCGSQDEESDLERLKEEIEK 650
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 988 VERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSMMEMQGQELHRKLGVLEEE-----V 1062
Cdd:TIGR00606 651 SSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlG 730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1063 RAARRAQE---------ETRGQQQALLRDHEALVQLQRRQETELEGLLVRH---RDLKANMRALELAHRELQGRHEQLQA 1130
Cdd:TIGR00606 731 LAPGRQSIidlkekeipELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEesaKVCLTDVTIMERFQMELKDVERKIAQ 810
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1131 QRANVEAQEVALLAE--RERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELERAQL 1208
Cdd:TIGR00606 811 QAAKLQGSDLDRTVQqvNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQL 890
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1209 EIQSQQLRESNQQLDLSACRL----TTQCELLTQ---LRSAQEEENRQLLAEVQALSRE-------NRELLERSLESRDH 1274
Cdd:TIGR00606 891 VELSTEVQSLIREIKDAKEQDspleTFLEKDQQEkeeLISSKETSNKKAQDKVNDIKEKvknihgyMKDIENKIQDGKDD 970
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 755563857 1275 LHREQREYLDQLNALRREKQKLVEKIMDQYRVLEPGPLPRTKKGSWLADK 1324
Cdd:TIGR00606 971 YLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDN 1020
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
261-524 |
6.49e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 261 LALQLTNAKAQLRRLRQEVEEKAEQLldsQAEVQGLEAEIRRLRQETQALSAQakraelyrEEAEALREragRLPRLQEE 340
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQLPEL---RKELEEAEAALEEFRQKNGLVDLS--------EEAKLLLQ---QLSELESQ 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 341 LRRCREKLQAAEVFKGQLEEErvLSEALEASKVLLEEQleVARERSARLHETQRENLLLRTRLGEAHADLDSLRHQLEQL 420
Cdd:COG3206 228 LAEARAELAEAEARLAALRAQ--LGSGPDALPELLQSP--VIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAAL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 421 VEENVELELELQRSLEpppgsPGEASLPGAAPSLQDEVR--EAEAGRLRAVERENRELRGQLQMLQAQLGSQHPLLEEQR 498
Cdd:COG3206 304 RAQLQQEAQRILASLE-----AELEALQAREASLQAQLAqlEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
250 260
....*....|....*....|....*...
gi 755563857 499 ENSRQPPVPNR--DPATPSALHHSPQSP 524
Cdd:COG3206 379 LAEALTVGNVRviDPAVVPLKPVSPKKL 406
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
828-1172 |
6.65e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.16 E-value: 6.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALER 907
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 908 QKFLQEQENQHQRYRHLEQRLeaelqaasTSKEEALMELKARALQLEEELIQL-RQYpvdlatgaRAGPRTVETQNGRLI 986
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLTNQD--------SVKELIIKNLDNTRESLETQLKVLsRSI--------NKIKQNLEQKQKELK 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 987 EVERNNATLVAEKAALQGQLQHLEGQlgslqgraQELLLQSQRAqehssrLQAEKSMMEMQGQELHRKLGVLEEEVRAAr 1066
Cdd:TIGR04523 493 SKEKELKKLNEEKKELEEKVKDLTKK--------ISSLKEKIEK------LESEKKEKESKISDLEDELNKDDFELKKE- 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1067 RAQEETRGQQQallrdhealvqlqrrqetELEgllvrhrDLKANMRALELAHRELQGRHEQLQAQRANVEAQevalLAER 1146
Cdd:TIGR04523 558 NLEKEIDEKNK------------------EIE-------ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKE----IEEK 608
|
330 340
....*....|....*....|....*.
gi 755563857 1147 ERLMQDghrqrgLEEELRRLQNEHER 1172
Cdd:TIGR04523 609 EKKISS------LEKELEKAKKENEK 628
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
843-1302 |
7.35e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 7.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 843 QVEAAEQQVQALESQVRchLEEAEREHAEKQALREELEKAVLRGQElgdrlehlqeelEQAALERQKFLQEQENQhQRYR 922
Cdd:TIGR00606 465 QLEGSSDRILELDQELR--KAERELSKAEKNSLTETLKKEVKSLQN------------EKADLDRKLRKLDQEME-QLNH 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 923 HLEQRLEAE-LQAASTSKEEALMELKARAlqlEEELIQLRQY---PVDLATGARAGPRTVETQNGRLIEVERNNATLVAE 998
Cdd:TIGR00606 530 HTTTRTQMEmLTKDKMDKDEQIRKIKSRH---SDELTSLLGYfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQN 606
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 999 KAALQGQLQHLEGQLGSLQGR--------AQELLLQSQRAQEHSSRLQ--------------AEKSMMEMQG-------- 1048
Cdd:TIGR00606 607 KNHINNELESKEEQLSSYEDKlfdvcgsqDEESDLERLKEEIEKSSKQramlagatavysqfITQLTDENQSccpvcqrv 686
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1049 ----QELHRKLGVLEEEVRAARRAQEETRGQqqallrdheaLVQLQRRQETELEGLLVRHRDLKANMRALELAHRELQGR 1124
Cdd:TIGR00606 687 fqteAELQEFISDLQSKLRLAPDKLKSTESE----------LKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKV 756
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1125 HEQLQAQRANVEAQEVAL--LAERERLMQDGHRQRGLEEELRRLQNEHERAQMLLAE----------VSRERGELQGERG 1192
Cdd:TIGR00606 757 NRDIQRLKNDIEEQETLLgtIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAklqgsdldrtVQQVNQEKQEKQH 836
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1193 ELRSRLARLELERAQLEIQSQQLRESNQQL-DLSACRLTTQCELltQLRSAQEEENRQLLAEVQALSRENRELLERSLES 1271
Cdd:TIGR00606 837 ELDTVVSKIELNRKLIQDQQEQIQHLKSKTnELKSEKLQIGTNL--QRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPL 914
|
490 500 510
....*....|....*....|....*....|.
gi 755563857 1272 RDHLHREQREYLDQLNALRREKQKLVEKIMD 1302
Cdd:TIGR00606 915 ETFLEKDQQEKEELISSKETSNKKAQDKVND 945
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
828-950 |
7.86e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.53 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 828 RERRQWERDGPRLRAQVEAAEQQVQALESQVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEElEQAALER 907
Cdd:PRK12704 68 KLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE-QLQELER 146
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 755563857 908 QKFLQEQENQHQRYRHLEQrlEAELQAAST---SKEEALMELKARA 950
Cdd:PRK12704 147 ISGLTAEEAKEILLEKVEE--EARHEAAVLikeIEEEAKEEADKKA 190
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
262-419 |
8.30e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 8.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 262 ALQLTNAKAQLRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYR----EEAEALRERAgrlprl 337
Cdd:COG4717 318 EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAeagvEDEEELRAAL------ 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 338 qEELRRCREKLQAAEVFKGQLEEErvLSEALEASKVLLEEQLEvarersARLHETQRENLLLRTRLGEAHADLDSLRHQL 417
Cdd:COG4717 392 -EQAEEYQELKEELEELEEQLEEL--LGELEELLEALDEEELE------EELEELEEELEELEEELEELREELAELEAEL 462
|
..
gi 755563857 418 EQ 419
Cdd:COG4717 463 EQ 464
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
204-372 |
8.35e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.52 E-value: 8.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 204 EELEMQLRSLTGMMSRLARERDLGAQRLAELL-------LEREPAHLLLPEAPANASAEG-VSHHLALQLTNAKAQLRRL 275
Cdd:COG4942 79 AALEAELAELEKEIAELRAELEAQKEELAELLralyrlgRQPPLALLLSPEDFLDAVRRLqYLKYLAPARREQAEELRAD 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 276 RQEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQAlsAQAKRAELYREEAEALRERAGRLPRLQEELRRCREKLQAAEVfK 355
Cdd:COG4942 159 LAELAALRAELEAERAELEALLAELEEERAALEA--LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA-E 235
|
170
....*....|....*..
gi 755563857 356 GQLEEERVLSEALEASK 372
Cdd:COG4942 236 AAAAAERTPAAGFAALK 252
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
437-615 |
8.50e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 40.91 E-value: 8.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 437 PPPGSPGEASLPGAAPSLQDEVREAEAGRLRAVERenrelrgQLQMLQAQLGSQHPLLEEqrenSRQPPVPNRDP--ATP 514
Cdd:pfam03154 199 PTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQ-------TPTLHPQRLPSPHPPLQP----MTQPPPPSQVSpqPLP 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 515 SALHHSPQSPACQIGGEGSESLDLP-SPASYSDITRSPKCSQAPDSHPELESPLQMVSQDPQTSDQALQESDPTvethqc 593
Cdd:pfam03154 268 QPSLHGQMPPMPHSLQTGPSHMQHPvPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPR------ 341
|
170 180
....*....|....*....|..
gi 755563857 594 lEKSGHRVPLQSPIVWDPPQGP 615
Cdd:pfam03154 342 -EQPLPPAPLSMPHIKPPPTTP 362
|
|
| HAUS6_N |
pfam14661 |
HAUS augmin-like complex subunit 6 N-terminus; This family includes the N-terminus of HAUS ... |
231-347 |
8.65e-03 |
|
HAUS augmin-like complex subunit 6 N-terminus; This family includes the N-terminus of HAUS augmin-like complex subunit 6. The HAUS augmin-like complex contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis.
Pssm-ID: 464244 [Multi-domain] Cd Length: 233 Bit Score: 39.56 E-value: 8.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 231 LAELLLEREPAHLLLPE-----APANASAEGVSHHLALQLTNAKaqlRRLRQEVEEKAEQLLDSQAEVQGLEAEIRRLRQ 305
Cdd:pfam14661 119 LKKVLKTRSKNGGGFPAlaqklALENRGYSGEQAELAALILAHR---SSLLRILEEKDALIQKYQQFAQLLVKKIRALRA 195
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 755563857 306 ETQALSAQAKRAELYREEAEALREragrlpRLQEELRRCREK 347
Cdd:pfam14661 196 EREKLDALLKKMEKDNRSRSAEQD------ALQEKIDKVRNL 231
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
997-1275 |
9.31e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 9.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 997 AEKAALQGQLQhlegqlgslqgRAQELLLQSQRAQEHSSRL-----QAEKSMMEMQgqelhRKLGVLEEEVRAARRAQEE 1071
Cdd:PRK11281 56 AEDKLVQQDLE-----------QTLALLDKIDRQKEETEQLkqqlaQAPAKLRQAQ-----AELEALKDDNDEETRETLS 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1072 TRGQQQALLRDHEALVQLQRRQET--ELEGLLVrhrdlkANMRALELAHREL---QGRHEQLQAQRANVEAQEVALLAER 1146
Cdd:PRK11281 120 TLSLRQLESRLAQTLDQLQNAQNDlaEYNSQLV------SLQTQPERAQAALyanSQRLQQIRNLLKGGKVGGKALRPSQ 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 1147 ERLMQdghrqrgLEEELRRLQNEHERAqmLLAEVSRERGELQGERGELRSRLARLELERAQLE--IQSQQLRESNQQLdl 1224
Cdd:PRK11281 194 RVLLQ-------AEQALLNAQNDLQRK--SLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQeaINSKRLTLSEKTV-- 262
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 755563857 1225 sacrlttqcellTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHL 1275
Cdd:PRK11281 263 ------------QEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKL 301
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
800-1040 |
9.76e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.13 E-value: 9.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 800 EAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALESQvrchLEEAEREHAEKQALREEL 879
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 880 EKAV-LRGQELGDRLEHLQEELEQAALerqKFLQEQENQHQRYRHLEQrleaeLQAASTSKEEALMELKARAlqleEELI 958
Cdd:COG4942 96 RAELeAQKEELAELLRALYRLGRQPPL---ALLLSPEDFLDAVRRLQY-----LKYLAPARREQAEELRADL----AELA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 959 QLRQYPVDLAtgaragprtvETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQ 1038
Cdd:COG4942 164 ALRAELEAER----------AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
|
..
gi 755563857 1039 AE 1040
Cdd:COG4942 234 AE 235
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
261-501 |
9.90e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 40.33 E-value: 9.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 261 LALQLTNAKAQLRRLRQEVEEKAEQLldsqaevqgleaeirRLRQETQALSAQAKRAELYREEAEALRERAGRLPRLQEE 340
Cdd:COG5185 280 LNENANNLIKQFENTKEKIAEYTKSI---------------DIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTAE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 341 LRRCREKLQAAEVFKGQLEEERVLSEALEASKVLLEE---QLEVARERSARLHETQRE-----NLLLRTRLGEAHADLDS 412
Cdd:COG5185 345 IEQGQESLTENLEAIKEEIENIVGEVELSKSSEELDSfkdTIESTKESLDEIPQNQRGyaqeiLATLEDTLKAADRQIEE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755563857 413 LRHQLEQlveeNVELELELQRSLEPPPGSpGEASLPGAAPSLQDEVREAEAGRLRAVERENRELRGQLQMLQAQLGSQHP 492
Cdd:COG5185 425 LQRQIEQ----ATSSNEEVSKLLNELISE-LNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKA 499
|
....*....
gi 755563857 493 LLEEQRENS 501
Cdd:COG5185 500 TLEKLRAKL 508
|
|
| |
