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Conserved domains on  [gi|767938382|ref|XP_011532856|]
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SUMO-interacting motif-containing protein 1 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
146-372 7.92e-05

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 7.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  146 GPPPatsisgGSVYPTEPNCSSATFTGNLSFLASLQLSSDVSSLSPTSNNSRSSSSSSNQKAPLPCPQQDVSRPPQALPC 225
Cdd:PHA03307   70 GPPP------GPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGS 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  226 PLRPLPCpprASPCPPRASSCPPRALSCPSQTMqcqlPALTHPPQEVPCP--RQNIPGPPQDSLGLPQDVPGLPQSILHP 303
Cdd:PHA03307  144 PGPPPAA---SPPAAGASPAAVASDAASSRQAA----LPLSSPEETARAPssPPAEPPPSTPPAAASPRPPRRSSPISAS 216
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  304 QDVAYLQDMPRSPGDVPQSPSDVSPSPDAPQSPGGMPHLPGDVlHSPGDMPHSSGD-VTHSPRDIPHLPG 372
Cdd:PHA03307  217 ASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPR-PAPITLPTRIWEaSGWNGPSSRPGPA 285
 
Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
146-372 7.92e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 7.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  146 GPPPatsisgGSVYPTEPNCSSATFTGNLSFLASLQLSSDVSSLSPTSNNSRSSSSSSNQKAPLPCPQQDVSRPPQALPC 225
Cdd:PHA03307   70 GPPP------GPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGS 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  226 PLRPLPCpprASPCPPRASSCPPRALSCPSQTMqcqlPALTHPPQEVPCP--RQNIPGPPQDSLGLPQDVPGLPQSILHP 303
Cdd:PHA03307  144 PGPPPAA---SPPAAGASPAAVASDAASSRQAA----LPLSSPEETARAPssPPAEPPPSTPPAAASPRPPRRSSPISAS 216
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  304 QDVAYLQDMPRSPGDVPQSPSDVSPSPDAPQSPGGMPHLPGDVlHSPGDMPHSSGD-VTHSPRDIPHLPG 372
Cdd:PHA03307  217 ASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPR-PAPITLPTRIWEaSGWNGPSSRPGPA 285
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
254-388 1.85e-03

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 41.92  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  254 PSQTMQCQLPAlthpPQEVPCPRQNIPGPP----QDSLGLPQDVPGLPQSILHPQDVAYLQDMPRSPGD-VPQSPSDVSP 328
Cdd:pfam09606 327 QQQMNQSVGQG----GQVVALGGLNHLETWnpgnFGGLGANPMQRGQPGMMSSPSPVPGQQVRQVTPNQfMRQSPQPSVP 402
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  329 SPDAPQSPGGMPHlPGDVLHSPGDMPHSSGDVTHSPRDIPHLPGDRPDFTQNDVQNRDMP 388
Cdd:pfam09606 403 SPQGPGSQPPQSH-PGGMIPSPALIPSPSPQMSQQPAQQRTIGQDSPGGSLNTPGQSAVN 461
 
Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
146-372 7.92e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 7.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  146 GPPPatsisgGSVYPTEPNCSSATFTGNLSFLASLQLSSDVSSLSPTSNNSRSSSSSSNQKAPLPCPQQDVSRPPQALPC 225
Cdd:PHA03307   70 GPPP------GPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGS 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  226 PLRPLPCpprASPCPPRASSCPPRALSCPSQTMqcqlPALTHPPQEVPCP--RQNIPGPPQDSLGLPQDVPGLPQSILHP 303
Cdd:PHA03307  144 PGPPPAA---SPPAAGASPAAVASDAASSRQAA----LPLSSPEETARAPssPPAEPPPSTPPAAASPRPPRRSSPISAS 216
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  304 QDVAYLQDMPRSPGDVPQSPSDVSPSPDAPQSPGGMPHLPGDVlHSPGDMPHSSGD-VTHSPRDIPHLPG 372
Cdd:PHA03307  217 ASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPR-PAPITLPTRIWEaSGWNGPSSRPGPA 285
PHA02682 PHA02682
ORF080 virion core protein; Provisional
236-367 2.43e-04

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 44.08  E-value: 2.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382 236 ASPCPPRASSCPPRALSCPSQTMQCQLPALTHPPQEVP---CPRQNIPGPPQDSLGLPQDVPGLPQSILHPQdvaylqdm 312
Cdd:PHA02682  99 APAAPAPAVTCPAPAPACPPATAPTCPPPAVCPAPARPapaCPPSTRQCPPAPPLPTPKPAPAAKPIFLHNQ-------- 170
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382 313 pRSPGDVPQSP-SDVSPSPDApqSPGGMPHLPGDVLHSPGD----MPHSSGDVTHSPRDI 367
Cdd:PHA02682 171 -LPPPDYPAAScPTIETAPAA--SPVLEPRIPDKIIDADNDdkdlIKKELADIADSVRDL 227
PHA03247 PHA03247
large tegument protein UL36; Provisional
74-381 3.89e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382   74 AEGENRPIATLDLTLEPVTPSQKEPTSLQTCASLSGKAVMEGHVDRSSQPTARriinsDPVDLDLVEENTFVGPPPATSI 153
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPW-----DPADPPAAVLAPAAALPPAASP 2824
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  154 SGG-----SVYPTEPNCSSATFTGNLSFLASLQLSSDVSSLSPTSNNSRSSSsssnqkAPLPCPQQDVSRPPqalpcplR 228
Cdd:PHA03247 2825 AGPlppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPA------APARPPVRRLARPA-------V 2891
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  229 PLPCPPRASPCPPRASSCPPRALSCPSQTMQCQLPALTHPPQEVPcPRQNIPGPPQ-DSLGLPQDVPGLPQ---SILHPQ 304
Cdd:PHA03247 2892 SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP-PRPQPPLAPTtDPAGAGEPSGAVPQpwlGALVPG 2970
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767938382  305 DVAYLQDMPRSPGDVPQSPSDVSPSPDAPQSPGGMPHLPGDVLHSPGDMPHSSGDVT-HSPRDIPHLPGDRPDFTQND 381
Cdd:PHA03247 2971 RVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKQTlWPPDDTEDSDADSLFDSDSE 3048
PHA03247 PHA03247
large tegument protein UL36; Provisional
207-437 6.29e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 6.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  207 APLPcPQQDVSRPPQALPCPLRPLPCPPRASPCPPRASSCPPRALSCPSQTM-QCQLPALTHPP--QEVPCPRQNIPGPP 283
Cdd:PHA03247 2768 APAP-PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALpPAASPAGPLPPptSAQPTAPPPPPGPP 2846
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  284 QDSLGL---------------PQDVPGLPQSILHPQDVAYLQ-DMPRSPGDVPQSPSDVS--PSPDAPQSPGGMPHLPGD 345
Cdd:PHA03247 2847 PPSLPLggsvapggdvrrrppSRSPAAKPAAPARPPVRRLARpAVSRSTESFALPPDQPErpPQPQAPPPPQPQPQPPPP 2926
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  346 VLHSPGDMPHSSGDVTHSPRDIPHLPGDRPDFTQNDVQNRDMPMDISALSSPSCSPSPQSETPLEKVPWLSVMETPA--- 422
Cdd:PHA03247 2927 PQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRvss 3006
                         250
                  ....*....|....*.
gi 767938382  423 -RKEISLSEPAKPGSA 437
Cdd:PHA03247 3007 wASSLALHEETDPPPV 3022
PHA03379 PHA03379
EBNA-3A; Provisional
212-452 9.69e-04

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 43.12  E-value: 9.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382 212 PQQDVSRP-PQALPCPLRPLPCPPRASPCPPRASSCPPRALSCPSQTMQCQLPALTHPPQEVPCPRQNIPGPPQDSLGLP 290
Cdd:PHA03379 416 PRPPVEKPrPEVPQSLETATSHGSAQVPEPPPVHDLEPGPLHDQHSMAPCPVAQLPPGPLQDLEPGDQLPGVVQDGRPAC 495
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382 291 QDVPGLPQSILHPQDVAYLQDMPRSPGDV-PQS-PSDVSPSPDAPQSPGGMPHLPGDVLHSPGDmPHSSGDVTHSPRDIP 368
Cdd:PHA03379 496 APVPAPAGPIVRPWEASLSQVPGVAFAPVmPQPmPVEPVPVPTVALERPVCPAPPLIAMQGPGE-TSGIVRVRERWRPAP 574
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382 369 HLPG-----------DRPDFTQNDVQNRDMPMDISALSSPSCSPSPQSETPLE------------------KVPWLSVME 419
Cdd:PHA03379 575 WTPNpprspsqmsvrDRLARLRAEAQPYQASVEVQPPQLTQVSPQQPMEYPLEpeqqmfpgspfsqvadvmRAGGVPAMQ 654
                        250       260       270
                 ....*....|....*....|....*....|...
gi 767938382 420 TPARkEISLSEPAKPGSAHVQSRTPQGGLYNRP 452
Cdd:PHA03379 655 PQYF-DLPLQQPISQGAPLAPLRASMGPVPPVP 686
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
254-388 1.85e-03

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 41.92  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  254 PSQTMQCQLPAlthpPQEVPCPRQNIPGPP----QDSLGLPQDVPGLPQSILHPQDVAYLQDMPRSPGD-VPQSPSDVSP 328
Cdd:pfam09606 327 QQQMNQSVGQG----GQVVALGGLNHLETWnpgnFGGLGANPMQRGQPGMMSSPSPVPGQQVRQVTPNQfMRQSPQPSVP 402
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  329 SPDAPQSPGGMPHlPGDVLHSPGDMPHSSGDVTHSPRDIPHLPGDRPDFTQNDVQNRDMP 388
Cdd:pfam09606 403 SPQGPGSQPPQSH-PGGMIPSPALIPSPSPQMSQQPAQQRTIGQDSPGGSLNTPGQSAVN 461
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
206-348 3.55e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.17  E-value: 3.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938382  206 KAPLPCPQQDVSRPPQALPCPLRPLPCPPRASPCPPRASSCPPRALSCPsqtmqcQLPALTHPPQEVPCPRQNIPGPPQD 285
Cdd:pfam09770 206 QAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQ------QHPGQGHPVTILQRPQSPQPDPAQP 279
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767938382  286 SLGLPQDVPGLPQSILHPQDVAYLQDMPRSPGDV------PQSPSDVSPSPDAPQSPGGMPHLPGDVLH 348
Cdd:pfam09770 280 SIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARvgypqnPQPGVQPAPAHQAHRQQGSFGRQAPIITH 348
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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