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Conserved domains on  [gi|1002236984|ref|XP_015622692|]
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pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha [Oryza sativa Japonica Group]

Protein Classification

pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha( domain architecture ID 10010973)

pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha is the regulatory subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase that catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis

EC:  2.7.1.90
Gene Ontology:  GO:0003872|GO:0006002|GO:0046872|GO:0047334

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN03028 PLN03028
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
 8-617 0e+00

pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional


:

Pssm-ID: 215543  Cd Length: 610  Bit Score: 1302.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   8 PRELSEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFLRKTANVPDATVISEHPVV 87
Cdd:PLN03028    1 PRELSGLQKLRSLYQPELPPCLQGTTVRVELGDATTAADPADAHAISRAFPHTYGQPLAHFLRATAKVPDAQVITEHPAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTE 167
Cdd:PLN03028   81 RVGVVFCGRQSPGGHNVIWGLHDALKAHNPNSVLLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGYDLLGRTKDQIRTTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 168 QVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISN 247
Cdd:PLN03028  161 QVNAALAACEALKLDGLVIIGGVTSNTDAAQLAETFAEAKCKTKVVGVPVTLNGDLKNQFVETNVGFDTICKVNSQLISN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 248 VCTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEG 327
Cdd:PLN03028  241 VCTDALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILGEEVAASKLTLFDITKQICDAVQARAEQDKNHGVILIPEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 328 LVESIPELYALLQEIHGLHGKGVSMENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEM 407
Cdd:PLN03028  321 LIESIPEVYALLQEIHGLLKQGVSVDNISSQLSPWASALFEFLPPFIKKQLLLHPESDDSAQLSQIETEKLLAQLVETEM 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 408 NRRMKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSM 487
Cdd:PLN03028  401 NKRTKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATVTNLKSPVNKWRCGAAPITAM 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 488 MTVKRWSRGPAATQIGKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGADSKPISLCVEDQDYMGRIK 567
Cdd:PLN03028  481 MSVKRWSRGPGASQIGKPAIHPAPVDLKGKAYELLRQNASSFLMDDLYRNPGPLQFDGPGADAKPITLCVEDQDYMGRIK 560

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002236984 568 KLQEYLEKVKSIVKPGCSQDVLKAALSAMSSVTETLAIMTSSSTGQGTPL 617
Cdd:PLN03028  561 KLQEYLDKVRTIVKPGCSQEVLKAALSSMASVTDVLTVMSSPSNRGLTPL 610
 
Name Accession Description Interval E-value
PLN03028 PLN03028
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
 8-617 0e+00

pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional


Pssm-ID: 215543  Cd Length: 610  Bit Score: 1302.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   8 PRELSEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFLRKTANVPDATVISEHPVV 87
Cdd:PLN03028    1 PRELSGLQKLRSLYQPELPPCLQGTTVRVELGDATTAADPADAHAISRAFPHTYGQPLAHFLRATAKVPDAQVITEHPAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTE 167
Cdd:PLN03028   81 RVGVVFCGRQSPGGHNVIWGLHDALKAHNPNSVLLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGYDLLGRTKDQIRTTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 168 QVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISN 247
Cdd:PLN03028  161 QVNAALAACEALKLDGLVIIGGVTSNTDAAQLAETFAEAKCKTKVVGVPVTLNGDLKNQFVETNVGFDTICKVNSQLISN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 248 VCTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEG 327
Cdd:PLN03028  241 VCTDALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILGEEVAASKLTLFDITKQICDAVQARAEQDKNHGVILIPEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 328 LVESIPELYALLQEIHGLHGKGVSMENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEM 407
Cdd:PLN03028  321 LIESIPEVYALLQEIHGLLKQGVSVDNISSQLSPWASALFEFLPPFIKKQLLLHPESDDSAQLSQIETEKLLAQLVETEM 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 408 NRRMKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSM 487
Cdd:PLN03028  401 NKRTKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATVTNLKSPVNKWRCGAAPITAM 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 488 MTVKRWSRGPAATQIGKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGADSKPISLCVEDQDYMGRIK 567
Cdd:PLN03028  481 MSVKRWSRGPGASQIGKPAIHPAPVDLKGKAYELLRQNASSFLMDDLYRNPGPLQFDGPGADAKPITLCVEDQDYMGRIK 560

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002236984 568 KLQEYLEKVKSIVKPGCSQDVLKAALSAMSSVTETLAIMTSSSTGQGTPL 617
Cdd:PLN03028  561 KLQEYLDKVRTIVKPGCSQEVLKAALSSMASVTDVLTVMSSPSNRGLTPL 610
PFKA_PPi TIGR02477
diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate ...
 14-559 0e+00

diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate 1-phosphotransferase catalyzes the addition of phosphate from diphosphate (PPi) to fructose 6-phosphate to give fructose 1,6-bisphosphate (EC 2.7.1.90). The enzyme is also known as pyrophosphate-dependent phosphofructokinase. The usage of PPi-dependent enzymes in glycolysis presumably frees up ATP for other processes. TIGR02482 represents the ATP-dependent 6-phosphofructokinase enzyme contained within pfam00365: Phosphofructokinase. This model hits primarily bacterial, plant alpha, and plant beta sequences. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 131530 [Multi-domain]  Cd Length: 539  Bit Score: 800.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  14 VQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFLRKTANVpdatviSEHPVVRVGVVF 93
Cdd:TIGR02477   1 LQQSRLQYVPKLPKVLQGDTANISLEDGEPTAAVADQEELKELFPNTYGLPIITFEPGEASP------DEHQPLKIGVIL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  94 CGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTEQVNGAM 173
Cdd:TIGR02477  75 SGGQAPGGHNVISGLFDALKKLNPNSKLYGFIGGPLGLLDNNYVELTKELIDTYRNTGGFDIIGSGRTKIETEEQFAKAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 174 ASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNVCTDAL 253
Cdd:TIGR02477 155 TTAKKLKLDGLVIIGGDDSNTNAALLAEYFAKHGLKTQVIGVPKTIDGDLKNQFIETSFGFDTACKIYSELIGNICRDAL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 254 SAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGLVESIP 333
Cdd:TIGR02477 235 SAKKYWHFIRLMGRSASHIALECALQTHPNVCIIGEEVAAKKMTLSQLTDYIADVIVKRAAKGKNFGVILIPEGLIEFIP 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 334 ELYALLQEIHGLHGKGVS----MENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEMNR 409
Cdd:TIGR02477 315 EVQALIKELNNLLAQNVLeegrKDNVQSKLSPSSKALFESLPEFIRHQLLLDRDPHGNVQVSQIETEKLLIELVQTELNK 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 410 RMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSMMT 489
Cdd:TIGR02477 395 RKKEGEYKG-KFSAVSHFFGYEGRCAFPSNFDSDYCYALGYTAAILLANGLTGYMSTIKNLTNPAEEWIAGGVPLTMMMN 473

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002236984 490 VKRWSrgpaatQIGKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAG--ADSKPISLCVED 559
Cdd:TIGR02477 474 MERRH------GEMKPVIKKALVDLEGKPFKKFASNRDKWALEDLYVFPGPIQYFGPEevCDQPTLTLLLEQ 539
Pyrophosphate_PFK cd00765
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ...
 12-558 1.57e-162

Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.


Pssm-ID: 238390  Cd Length: 550  Bit Score: 476.29  E-value: 1.57e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  12 SEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFlrktanVPDATVISEHPVVRVGV 91
Cdd:cd00765     4 SLVQQERINYTPKLPSVLKGDFNNIKIVEGPATSAAGDPDALAKLFPGTYGQPSVAF------VPDQDAPSSAPKLKIGI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  92 VFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTEQVNG 171
Cdd:cd00765    78 VLSGGQAPGGHNVISGLFDYLKERAKGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGFDMICSGRTKIETEDQFKQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 172 AMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNVCTD 251
Cdd:cd00765   158 AEETAKKLDLDALVVIGGDDSNTNAALLAENFRSKGLKTRVIGVPKTIDGDLKNKEIETSFGFDTATKIYSELIGNVMRD 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 252 ALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGLVES 331
Cdd:cd00765   238 ARSTGKYWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITDYMVDVICKRAELGYNFGVVLVPEGLIEF 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 332 IPELYALL-----------QEIHGLHGKGVSMENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLA 400
Cdd:cd00765   318 IPEVKELIaelneilanevVEFNGLWKKKLTEQSLKLFDLLPKGVYLPLFIEAIQEQLMLERDPHGNVQVSRIETEKLLI 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 401 QLVEDEMNRRMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCG 480
Cdd:cd00765   398 QMVETRLEKMKQAGAYKG-QFMGQSHFFGYEGRCAFPSNFDADYCYALGYGAGVLLNSGKTGYISSVGNLAAPVEEWTVG 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 481 AAPISSMMTVKRwSRGPAatqigKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEG--AGADSKPISLCVE 558
Cdd:cd00765   477 GVPLTMLMNMER-RHGKF-----KPVIKKALVDLEGAPFKKFASLREEWALKNRYIYPGPVQYTGpsEGSDELSHTLLLE 550
PfkA COG0205
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ...
 88-492 3.52e-43

6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439975 [Multi-domain]  Cd Length: 344  Bit Score: 158.31  E-value: 3.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLheAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLG--RTKdQIRT 165
Cdd:COG0205     3 RIGILTSGGDAPGLNAAIRAV--VRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGG-TILGssRSK-PFKT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 166 TEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFaeakcATKVVGVPVTLNGDLKnqFVETTVGFDTICKVNSQLI 245
Cdd:COG0205    79 EEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEY-----GIPVVGIPKTIDNDLP--GTDYTIGFDTAVNTAAEAI 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 246 SNVCTDALSAEKyYYFIRMMGRKASHVALECALQSHPNMVILGEEVaaskltiFDItKQICDAVQARAEKDKYHGVVLIP 325
Cdd:COG0205   152 DRLRDTAASHER-VFVVEVMGRHAGWLALAAGLAGGADLILIPEVP-------FDL-DKLLEKLKERRKRGKGYSIIVVA 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 326 EGLVESIPElyallqeihglhgkgvsmenissqlspwasalfeflppfirkqLLLHPESDDSAQLSQIETEKLLAQLVED 405
Cdd:COG0205   223 EGAGDEDGE-------------------------------------------AVLEADTDAFGHVRLGGIGEYLAKEIEE 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 406 EMNrrmkegtykgkkFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLkspankwRCGAAPIS 485
Cdd:COG0205   260 RTG------------IETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRG-------EIVLVPLE 320


                  ....*..
gi 1002236984 486 SMMTVKR 492
Cdd:COG0205   321 EVANKEK 327
PFK pfam00365
Phosphofructokinase;
88-345 2.17e-18

Phosphofructokinase;


Pssm-ID: 459783 [Multi-domain]  Cd Length: 271  Bit Score: 85.47  E-value: 2.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGL-HEAIKAhnpNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLG--RTKDQiR 164
Cdd:pfam00365   1 RIGILTSGGDAPGMNAAIRAVvRTAIYR---GHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGG-TILGtsRSKPF-K 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 165 TTEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAEtfaeaKCATKVVGVPVTLNGDLknQFVETTVGFDTICKVNSQL 244
Cdd:pfam00365  76 TEEGREKIAENLKKLGIDALVVIGGDGSLTGANKLSE-----ERGIPVVGIPKTIDNDI--PGTDYTIGFDTALNTIVEA 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 245 ISNVCTDALSAEKyYYFIRMMGRKASHVALECALQSHPNMVILGEEVaaskltiFDItKQICDAVQARAeKDKYHGVVLI 324
Cdd:pfam00365 149 IDRIRDTASSHNR-VFVVEVMGRHCGWLALMAGLAGGADAILIPEIP-------FDI-EELCEKIKELR-KGKRFSIIVV 218

                         250       260
                  ....*....|....*....|.
gi 1002236984 325 PEGlVESIPELYALLQEIHGL 345
Cdd:pfam00365 219 AEG-ASDGEFLAKLIEEGTGI 238
 
Name Accession Description Interval E-value
PLN03028 PLN03028
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
 8-617 0e+00

pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional


Pssm-ID: 215543  Cd Length: 610  Bit Score: 1302.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   8 PRELSEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFLRKTANVPDATVISEHPVV 87
Cdd:PLN03028    1 PRELSGLQKLRSLYQPELPPCLQGTTVRVELGDATTAADPADAHAISRAFPHTYGQPLAHFLRATAKVPDAQVITEHPAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTE 167
Cdd:PLN03028   81 RVGVVFCGRQSPGGHNVIWGLHDALKAHNPNSVLLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGYDLLGRTKDQIRTTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 168 QVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISN 247
Cdd:PLN03028  161 QVNAALAACEALKLDGLVIIGGVTSNTDAAQLAETFAEAKCKTKVVGVPVTLNGDLKNQFVETNVGFDTICKVNSQLISN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 248 VCTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEG 327
Cdd:PLN03028  241 VCTDALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILGEEVAASKLTLFDITKQICDAVQARAEQDKNHGVILIPEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 328 LVESIPELYALLQEIHGLHGKGVSMENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEM 407
Cdd:PLN03028  321 LIESIPEVYALLQEIHGLLKQGVSVDNISSQLSPWASALFEFLPPFIKKQLLLHPESDDSAQLSQIETEKLLAQLVETEM 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 408 NRRMKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSM 487
Cdd:PLN03028  401 NKRTKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATVTNLKSPVNKWRCGAAPITAM 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 488 MTVKRWSRGPAATQIGKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGADSKPISLCVEDQDYMGRIK 567
Cdd:PLN03028  481 MSVKRWSRGPGASQIGKPAIHPAPVDLKGKAYELLRQNASSFLMDDLYRNPGPLQFDGPGADAKPITLCVEDQDYMGRIK 560

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002236984 568 KLQEYLEKVKSIVKPGCSQDVLKAALSAMSSVTETLAIMTSSSTGQGTPL 617
Cdd:PLN03028  561 KLQEYLDKVRTIVKPGCSQEVLKAALSSMASVTDVLTVMSSPSNRGLTPL 610
PFKA_PPi TIGR02477
diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate ...
 14-559 0e+00

diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate 1-phosphotransferase catalyzes the addition of phosphate from diphosphate (PPi) to fructose 6-phosphate to give fructose 1,6-bisphosphate (EC 2.7.1.90). The enzyme is also known as pyrophosphate-dependent phosphofructokinase. The usage of PPi-dependent enzymes in glycolysis presumably frees up ATP for other processes. TIGR02482 represents the ATP-dependent 6-phosphofructokinase enzyme contained within pfam00365: Phosphofructokinase. This model hits primarily bacterial, plant alpha, and plant beta sequences. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 131530 [Multi-domain]  Cd Length: 539  Bit Score: 800.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  14 VQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFLRKTANVpdatviSEHPVVRVGVVF 93
Cdd:TIGR02477   1 LQQSRLQYVPKLPKVLQGDTANISLEDGEPTAAVADQEELKELFPNTYGLPIITFEPGEASP------DEHQPLKIGVIL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  94 CGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTEQVNGAM 173
Cdd:TIGR02477  75 SGGQAPGGHNVISGLFDALKKLNPNSKLYGFIGGPLGLLDNNYVELTKELIDTYRNTGGFDIIGSGRTKIETEEQFAKAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 174 ASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNVCTDAL 253
Cdd:TIGR02477 155 TTAKKLKLDGLVIIGGDDSNTNAALLAEYFAKHGLKTQVIGVPKTIDGDLKNQFIETSFGFDTACKIYSELIGNICRDAL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 254 SAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGLVESIP 333
Cdd:TIGR02477 235 SAKKYWHFIRLMGRSASHIALECALQTHPNVCIIGEEVAAKKMTLSQLTDYIADVIVKRAAKGKNFGVILIPEGLIEFIP 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 334 ELYALLQEIHGLHGKGVS----MENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEMNR 409
Cdd:TIGR02477 315 EVQALIKELNNLLAQNVLeegrKDNVQSKLSPSSKALFESLPEFIRHQLLLDRDPHGNVQVSQIETEKLLIELVQTELNK 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 410 RMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSMMT 489
Cdd:TIGR02477 395 RKKEGEYKG-KFSAVSHFFGYEGRCAFPSNFDSDYCYALGYTAAILLANGLTGYMSTIKNLTNPAEEWIAGGVPLTMMMN 473

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002236984 490 VKRWSrgpaatQIGKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAG--ADSKPISLCVED 559
Cdd:TIGR02477 474 MERRH------GEMKPVIKKALVDLEGKPFKKFASNRDKWALEDLYVFPGPIQYFGPEevCDQPTLTLLLEQ 539
PRK07085 PRK07085
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
 12-558 0e+00

diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional


Pssm-ID: 235930  Cd Length: 555  Bit Score: 599.21  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  12 SEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFLRKTAnvpdatviSEHPVVRVGV 91
Cdd:PRK07085    4 SYLQLARLKYRPKLPKLLQNDPGLIKIVDGEFTESVADQDELAELFPNTYGLPYVTFVKGSE--------SSSKPLKVGV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  92 VFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDML--GRTKdqIRTTEQV 169
Cdd:PRK07085   76 ILSGGQAPGGHNVIAGLFDGLKKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGFDMIgsGRTK--IETEEQK 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 170 NGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNVC 249
Cdd:PRK07085  154 EACLETVKKLKLDGLVIIGGDDSNTNAAILAEYFAKHGCKTQVIGVPKTIDGDLKNEFIETSFGFDTATKTYSEMIGNIS 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 250 TDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGLV 329
Cdd:PRK07085  234 RDALSAKKYWHFIKLMGRSASHIALECALQTHPNICLISEEVAEKKMSLQDIVHYIASVIADRAAKGKNYGVILIPEGLI 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 330 ESIPELYALLQEI------HGLHGKGVSMEN----ISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLL 399
Cdd:PRK07085  314 EFIPEMKSLIKELnsllaeNESEFKGLDTEAqreyIISKLSPESAKLFKSLPEDIARQLLLDRDPHGNVQVSKIETEKLL 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 400 AQLVEDEMNRRMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRC 479
Cdd:PRK07085  394 IEMVKKELEKLKPEGKYKG-PFSAISHFFGYEGRSAFPSNFDADYCYALGYTAALLILNGKTGYMSTIKNLTSPYTEWIA 472

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 480 GAAPISSMMTVKRwSRGpaatqIGKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGA--DSKPISLCV 557
Cdd:PRK07085  473 GAVPLTMMMNMER-RHG-----KEKPVIKKALVDLDGPPFKYFAKYRDIWALEDSYRFPGPLQYFGPEElcDQRTLTLLL 546


                  .
gi 1002236984 558 E 558
Cdd:PRK07085  547 E 547
Pyrophosphate_PFK cd00765
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ...
 12-558 1.57e-162

Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.


Pssm-ID: 238390  Cd Length: 550  Bit Score: 476.29  E-value: 1.57e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  12 SEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPHTYGQPLAHFlrktanVPDATVISEHPVVRVGV 91
Cdd:cd00765     4 SLVQQERINYTPKLPSVLKGDFNNIKIVEGPATSAAGDPDALAKLFPGTYGQPSVAF------VPDQDAPSSAPKLKIGI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  92 VFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTEQVNG 171
Cdd:cd00765    78 VLSGGQAPGGHNVISGLFDYLKERAKGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGFDMICSGRTKIETEDQFKQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 172 AMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNVCTD 251
Cdd:cd00765   158 AEETAKKLDLDALVVIGGDDSNTNAALLAENFRSKGLKTRVIGVPKTIDGDLKNKEIETSFGFDTATKIYSELIGNVMRD 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 252 ALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGLVES 331
Cdd:cd00765   238 ARSTGKYWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITDYMVDVICKRAELGYNFGVVLVPEGLIEF 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 332 IPELYALL-----------QEIHGLHGKGVSMENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLA 400
Cdd:cd00765   318 IPEVKELIaelneilanevVEFNGLWKKKLTEQSLKLFDLLPKGVYLPLFIEAIQEQLMLERDPHGNVQVSRIETEKLLI 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 401 QLVEDEMNRRMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCG 480
Cdd:cd00765   398 QMVETRLEKMKQAGAYKG-QFMGQSHFFGYEGRCAFPSNFDADYCYALGYGAGVLLNSGKTGYISSVGNLAAPVEEWTVG 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 481 AAPISSMMTVKRwSRGPAatqigKPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEG--AGADSKPISLCVE 558
Cdd:cd00765   477 GVPLTMLMNMER-RHGKF-----KPVIKKALVDLEGAPFKKFASLREEWALKNRYIYPGPVQYTGpsEGSDELSHTLLLE 550
PLN02251 PLN02251
pyrophosphate-dependent phosphofructokinase
 12-558 3.36e-158

pyrophosphate-dependent phosphofructokinase


Pssm-ID: 215140  Cd Length: 568  Bit Score: 465.81  E-value: 3.36e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  12 SEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGahvISHAFPHTYGQPLAHFlrktanVP-DATVISEHPVVRVG 90
Cdd:PLN02251   30 SEVQSSRIDHALPLPSVLKGPFKIVDGPPSSAAGNPEE---IAKLFPNLFGQPSVML------VPsQADALSSDQKLKIG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  91 VVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQIRTTEQVN 170
Cdd:PLN02251  101 VVLSGGQAPGGHNVISGIFDYLQEHAKGSVLYGFKGGPAGIMKCKYVELTAEFIYPYRNQGGFDMICSGRDKIETPEQFK 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 171 GAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNVCT 250
Cdd:PLN02251  181 QAEETATKLDLDGLVVIGGDDSNTNACLLAEYFRAKNLKTRVIGCPKTIDGDLKSKEVPTSFGFDTACKIYSEMIGNVMI 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 251 DALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGLVE 330
Cdd:PLN02251  261 DARSTGKYYHFVRLMGRAASHITLECALQTHPNITIIGEEVAAKKLTLKNVTDYIVDVICKRAELGYNYGVILIPEGLID 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 331 SIPELYALLQEIHGLHGKGVSMEN--ISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEMN 408
Cdd:PLN02251  341 FIPEVQHLIAELNEILAHDVVDEEghWKKKLKPQSLQLFDFLPHAIQEQLMLERDPHGNVQVAKIETEKMLIQMVETELE 420

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 409 RRMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSMM 488
Cdd:PLN02251  421 KRKQEGSYKG-HFKGQSHFFGYEGRCGLPTNFDATYCYALGYGAGALLHSGKTGLISSVGNLAAPVEEWTVGGTALTSLM 499

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002236984 489 TVKRwSRGPaatqiGKPAVHMATVDLKG---KAFELLRNnstSFLIDDIYRNPGPLQFEGAGADSKPISLCVE 558
Cdd:PLN02251  500 DVER-RHGK-----FKPVIKKAMVELEGapfKKFASLRD---EWALKNRYISPGPIQFSGPGSDATNHTLKLE 563
PTZ00468 PTZ00468
phosphofructokinase family protein; Provisional
 3-609 4.16e-120

phosphofructokinase family protein; Provisional


Pssm-ID: 185647 [Multi-domain]  Cd Length: 1328  Bit Score: 386.64  E-value: 4.16e-120
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984    3 SDYGVPRELSEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHaFPHTYGQPLAHFlrkTANVPDATVIS 82
Cdd:PTZ00468    23 SASSLHEGQSNMQMWRRRWEPCLPHILRSPLSIKEVSAFEGMGKMERSDVSSY-FPLTSGNSLVKF---EAISDGSSSWK 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   83 EHPVVRVGVVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQ 162
Cdd:PTZ00468    99 KFPARRIGVVLSGGQASGGHNVIAGLMSYIKLCNQSSQLFGFLGGPEGVYSERYRELTEDDINGILNQGGFNIICSGRHK 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  163 IRTTEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNS 242
Cdd:PTZ00468   179 IETEEQMRASLEICEKLKLHGLVVIGGDDSNTNAAVLAEYFKRNSSSTVVVGCPKTIDGDLKNEVIETSFGYDTAVKTYS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  243 QLISNVCTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVV 322
Cdd:PTZ00468   259 EQIGSIMDAIKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGEEIKEENRSLMSIVDEIVEMILKRDSLGKKHGIV 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  323 LIPEGLVESIPELYALLQEIHGLHGKGVSMENISSQLSPWASALFEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQL 402
Cdd:PTZ00468   339 LLPEGLIEFIPEFETLIKELNLILLKTNDRKQIIDSLSQEMKTLFLELPSDVQNQLLLERDPHGNVQVAKIATEELLVHM 418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  403 VEDEMNRRMKEGTYKgkkfNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWRCGAA 482
Cdd:PTZ00468   419 AKEKLEEVKKDYILD----NVKTHYFGYEGRCALPSNFDASYCFALGHTAAALIDNQRSGYMAVVRKLSLTPEQWEPAGC 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  483 PISSMMTVKrwsrgpaaTQIGK--PAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGADSKPISLC---V 557
Cdd:PTZ00468   495 PLTYMMNIE--------LRKGKsvPVIKKYLVDLKGQSYLAYCQVRSEWKLNDYYRNPGPIQFDGPNSGITNYMISpprV 566

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1002236984  558 EDqdyMGRIKKLQEYLEKVKSIVKPG----CSQDVLKAA-LSAMSSVTETLAIMTSS 609
Cdd:PTZ00468   567 ED---LLRMEDRDENKMTHKLCGSELsqnrCKDDLKIPKiLLSTASKFNDDLIISSS 620
PTZ00287 PTZ00287
6-phosphofructokinase; Provisional
 10-563 1.02e-111

6-phosphofructokinase; Provisional


Pssm-ID: 240345 [Multi-domain]  Cd Length: 1419  Bit Score: 365.13  E-value: 1.02e-111
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   10 ELSEVQKKRALYQPELPPCLQGttvrvEYGDAAIAadpagaHVISHAFPHTYgQPLAHFLRKTANVPDATV--ISEHP-- 85
Cdd:PTZ00287   105 DLSPLQYERIKYQPTLPKALAS-----EYQILEEN------HGDDFINKKDY-EEVKRFLKNLHNLPILNVkeTNNHEsf 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   86 ----VVRVGVVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKD 161
Cdd:PTZ00287   173 kggnVLKIGIILSGGPAPGGHNVISGIYDYAKRYNEQSQVIGFLGGIDGLYSKNYVTITDSLMNRFRNLGGFNMLWSGRG 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  162 QIRTTEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVN 241
Cdd:PTZ00287   253 KVRNKDDLIAIENIVAKLKLNGLVIIGGDGSNSNAALISEYFAERQIPISIIGIPKTIDGDLKSEAIEISFGFDTATKTY 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  242 SQLISNVCTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGV 321
Cdd:PTZ00287   333 SEVIGNLCTDVKTGHNVYHVVRVMGRSASHVVLECALQTRPNIVLIGEEVEKENLSLKDIVSNIVNTILKRRSLNKNYGV 412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  322 VLIPEGLVESIPELYALLQEIHGLHGKG-VSMENISSQLSPWasalfEFLPPFIRKQLLLHPESDDSAQLSQIETEKLLA 400
Cdd:PTZ00287   413 ILIPEGLIEFVPEMKILIGELNVILKEGpFDASKLKHSREVW-----DFLPSIIRDQLLMDRESTGYIQVGKIATERLII 487

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  401 QLVEDEMNRrmkegtYKGKKFNA--ICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLKSPANKWR 478
Cdd:PTZ00287   488 VLVESELAK------LNDNNLNIqfMAHYLGYEGRCAIPSNFDCNYCYALGYNAALLIDHKKTGYMSIIQNLEDSYANWI 561

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  479 CGAAPISSMMTVKRWSRGPAAtqigkPAVHMATVDLKGKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGADSKPISLCVE 558
Cdd:PTZ00287   562 PAAIPFLRIMHVNRDNTGKEF-----PAVKRYLVDLNSPLFNVLKEVRSLWSLYDLYRSPGPIQFNGHLSNSRCYTVKIP 636


                   ....*
gi 1002236984  559 DQDYM 563
Cdd:PTZ00287   637 TKDNL 641
PTZ00287 PTZ00287
6-phosphofructokinase; Provisional
 11-590 3.15e-107

6-phosphofructokinase; Provisional


Pssm-ID: 240345 [Multi-domain]  Cd Length: 1419  Bit Score: 352.80  E-value: 3.15e-107
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   11 LSEVQKKRALYQPELPPCLQGTTVRVEYGDAAIAADPAGAHVISHAFPH-TYGQPLAhfLRKTANVPDATVISEHpvVRV 89
Cdd:PTZ00287   764 MSELQTSRLYNKLELPELCSDLKAKVRAGKQYISNDPYTQKQILSNYPHmSYENKFQ--IQEIFHDKYATPISFE--IKI 839

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   90 GVVFCGRQSPGGHNVIWGLHEAIKAHNpnSKLIGFLGGSdGLLAQKTLEITDEVLSSYKNQGGYDMLGRTKDQ-IRTTEQ 168
Cdd:PTZ00287   840 GIVFLSRQAPGAMNVLCGLYRRLKLLK--GVCIAFYGLY-GLLNNKYIIIDDDNIAKHVNQGGLELTGNSPEHsLFDKEN 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  169 VNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNQFVETTVGFDTICKVNSQLISNV 248
Cdd:PTZ00287   917 RNKVCETVTNLQLNGLVMPGSNVTITEAALLAEYFLEKKIPTSVVGIPLTGSNNLIHELIETCVGFDSSTKVYASLIGNV 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  249 CTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKLTIFDITKQICDAVQARAEKDKYHGVVLIPEGL 328
Cdd:PTZ00287   997 LTDAVSMPKYWHFIRLMGRSPSHEVLECALQTHPNMVIISEEYGAADKTLWRVVQDIADVVCARAELGKNYGTVLIPDAL 1076

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  329 VESIPELYALLQEIHGL----HGKGVSME------NIS---------------------------SQLSPWASALFEFLP 371
Cdd:PTZ00287  1077 LMHLPHMKILLSEISDIlndaNEKGQLVEarndlvNLSttqhghlgstagtvagaeqplsaspwvSKLTPWSLALLKTFP 1156

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  372 PFIRKQLLlhpESD-DSAQLSQIETEKLLAQLVEDEMNRRMKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGH 450
Cdd:PTZ00287  1157 QFIIKELL---HVDlRSMRFEKLETEQLLLQMVKEELHQRKQKGKYSG-SFMGLTHFFGYQGRSSLPSEFDCKLAYSYGH 1232

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  451 VCYHILAAGLNGYMATVTNLKSPANKWRCGAAPISSMMTVKRWSRGP----AATQIGKPAVHMATVDLKGKAFELLRNNS 526
Cdd:PTZ00287  1233 AASIVIESGLTGYIVSIRGLCGNIKDWKLFAIPFISLMKILPRGQGSkylkSASKGDLPVIPSAPVDLNGKAYRSLKIAL 1312

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002236984  527 TSFLIDDIYRNPGPLQFEGAGADSKPISLCVEDQDYMGRIKKLQEYLEKVKSIVKPGCSQDVLK 590
Cdd:PTZ00287  1313 QKWQMEDRFCNPGPIQFEGNASNYYNRILFEEQSEYFEMLRYVECYANILKDTCRFGVSADYLK 1376
PFK cd00363
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ...
 88-492 5.33e-68

Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.


Pssm-ID: 238216 [Multi-domain]  Cd Length: 338  Bit Score: 224.48  E-value: 5.33e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLHEAIKAHNpnSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGYdMLGRTKDQIRTTE 167
Cdd:cd00363     2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEG--LEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGT-IIGSARCKEFRTE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 168 qvNGAMASCQALK---LDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKNqfVETTVGFDTICKVNSQL 244
Cdd:cd00363    79 --EGRAKAAENLKkhgIDALVVIGGDGSYTGADLLTEEWPSKYQGFNVIGLPGTIDNDIKG--TDYTIGFDTALKTIVEA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 245 ISNVCTDALSaEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASkltifDITKQICDAVQARAEKDKYHGVVLI 324
Cdd:cd00363   155 IDRIRDTASS-HQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAAD-----EWEEEMVDVIKKRRERGKRHGIVIV 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 325 PEGLVESIPelyallqeihglhgkgvsmenissqlspwasalfeflppfirkqlllhpesddsaqlsQIETEKLLAQLVE 404
Cdd:cd00363   229 AEGAIDFIP----------------------------------------------------------KPITEKLLAKLVE 250

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 405 DEMnrrmkegtykgkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLkspaNKWRCGAAPI 484
Cdd:cd00363   251 ERL------------GFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNL----NENQVVRHPL 314


                  ....*...
gi 1002236984 485 SSMMTVKR 492
Cdd:cd00363   315 TEAVNMTK 322
PTZ00468 PTZ00468
phosphofructokinase family protein; Provisional
 97-616 9.95e-58

phosphofructokinase family protein; Provisional


Pssm-ID: 185647 [Multi-domain]  Cd Length: 1328  Bit Score: 210.60  E-value: 9.95e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984   97 QSPGGHNVIWGLHEAIKAHNpnsKLIGFLGGSD-----GLLAQKTLEITDEVLSSYKNQGG--------YDMLGRTKDQI 163
Cdd:PTZ00468   686 STPGTQNVICGLVNGLPSLK---QLIVFKSLSDfyegkALKVDLTSEGSLEFFENSLNSGGcifpngveIKMNVSEKKYS 762

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  164 RTTEQV--------NGAMASCQAL-------------KLDALVIIGGVTSNTDAAQLAE-----TFAEAKCATKVVGVPV 217
Cdd:PTZ00468   763 NTTLKAndnqeftnSSCVLSCKGLvsndflsqllsffNMRAIAIVGNSEAATFGASLSEqlicmSLNGMKSEIPVVFVPV 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  218 TLNGDLKNQFVETTVGFDTICKVNSQLISNVCTDALSAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVAASKL- 296
Cdd:PTZ00468   843 CLENSISHQMIETCIGFDSVTKSISTLVGNLLTDSASATKYWYFMKMIGDKTSNVALEVGIQTHPNLVVIPERYADSKLs 922

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  297 ---------TIFDITKQICDAVQARAEKDKYHGVVLIPEGLVESI---PELYALL-----QEIHGLHGKGVSMENISSQL 359
Cdd:PTZ00468   923 vygsemagvTLDDIITEICDIICLRSNQGNNFGGLLVSEGLFDQVyptREYRKIFsrfstQNLCNASNSGNCEILGSESL 1002

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  360 SPWASALFE-FLPPFIRKQLLLHPESDDSAQLSQIETEKLLAQLVEDEMNRRMKEGTYKGkKFNAICHFFGYQARGSLPS 438
Cdd:PTZ00468  1003 SRYEKKVVEdFKLIFSDIDERLIENLINSRKICDVRTEIILSALVQKELKFRRSKNKIKN-GMNPVCFSFTDQVRACIPS 1081

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  439 KFDCDYAYVLGHVCYHILAAGL-NGYMATVTNLKSPANKWRCGAAPISSMMTV-----------KRWSRGPAATQIGKPA 506
Cdd:PTZ00468  1082 DFDSTLGLMYGMLASKIINSNLvGGYVTGIKGVLSQIDSWNMYAIPISSLMTLniegdkimdsrNNSNLSFESKKLLTES 1161

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  507 --------VHMA----TVDLK-GKAFELLRNNSTSFLIDDIYRNPGPLQFEGAGADSKPISLCVEDQDYMGRIKKLQEYL 573
Cdd:PTZ00468  1162 tlgnaghqLEFIcklnSVNMRnNPSFKLLMNHIEKWEVDNTYANPGPIQYFNLFKNLFNRTLFESEYVYTRNLKEMDQIL 1241

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1002236984  574 EKVKSIVKPGCSQDVLKAALSAMSSVTETLAIMTSSSTGQGTP 616
Cdd:PTZ00468  1242 LEIKTLCQLGVEKDILNSTIQHLKAIQNSISIMSSCNHRKSKP 1284
PfkA COG0205
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ...
 88-492 3.52e-43

6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439975 [Multi-domain]  Cd Length: 344  Bit Score: 158.31  E-value: 3.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLheAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLG--RTKdQIRT 165
Cdd:COG0205     3 RIGILTSGGDAPGLNAAIRAV--VRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGG-TILGssRSK-PFKT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 166 TEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAETFaeakcATKVVGVPVTLNGDLKnqFVETTVGFDTICKVNSQLI 245
Cdd:COG0205    79 EEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEY-----GIPVVGIPKTIDNDLP--GTDYTIGFDTAVNTAAEAI 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 246 SNVCTDALSAEKyYYFIRMMGRKASHVALECALQSHPNMVILGEEVaaskltiFDItKQICDAVQARAEKDKYHGVVLIP 325
Cdd:COG0205   152 DRLRDTAASHER-VFVVEVMGRHAGWLALAAGLAGGADLILIPEVP-------FDL-DKLLEKLKERRKRGKGYSIIVVA 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 326 EGLVESIPElyallqeihglhgkgvsmenissqlspwasalfeflppfirkqLLLHPESDDSAQLSQIETEKLLAQLVED 405
Cdd:COG0205   223 EGAGDEDGE-------------------------------------------AVLEADTDAFGHVRLGGIGEYLAKEIEE 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 406 EMNrrmkegtykgkkFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATVTNLkspankwRCGAAPIS 485
Cdd:COG0205   260 RTG------------IETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRG-------EIVLVPLE 320


                  ....*..
gi 1002236984 486 SMMTVKR 492
Cdd:COG0205   321 EVANKEK 327
PFK pfam00365
Phosphofructokinase;
88-345 2.17e-18

Phosphofructokinase;


Pssm-ID: 459783 [Multi-domain]  Cd Length: 271  Bit Score: 85.47  E-value: 2.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGL-HEAIKAhnpNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLG--RTKDQiR 164
Cdd:pfam00365   1 RIGILTSGGDAPGMNAAIRAVvRTAIYR---GHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGG-TILGtsRSKPF-K 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 165 TTEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAEtfaeaKCATKVVGVPVTLNGDLknQFVETTVGFDTICKVNSQL 244
Cdd:pfam00365  76 TEEGREKIAENLKKLGIDALVVIGGDGSLTGANKLSE-----ERGIPVVGIPKTIDNDI--PGTDYTIGFDTALNTIVEA 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 245 ISNVCTDALSAEKyYYFIRMMGRKASHVALECALQSHPNMVILGEEVaaskltiFDItKQICDAVQARAeKDKYHGVVLI 324
Cdd:pfam00365 149 IDRIRDTASSHNR-VFVVEVMGRHCGWLALMAGLAGGADAILIPEIP-------FDI-EELCEKIKELR-KGKRFSIIVV 218

                         250       260
                  ....*....|....*....|.
gi 1002236984 325 PEGlVESIPELYALLQEIHGL 345
Cdd:pfam00365 219 AEG-ASDGEFLAKLIEEGTGI 238
PRK03202 PRK03202
ATP-dependent 6-phosphofructokinase;
88-345 4.07e-16

ATP-dependent 6-phosphofructokinase;


Pssm-ID: 235111 [Multi-domain]  Cd Length: 320  Bit Score: 79.74  E-value: 4.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  88 RVGVVFCGRQSPGGHNVIWGLheAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLG--RTKdQIRT 165
Cdd:PRK03202    3 RIGVLTSGGDAPGMNAAIRAV--VRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGG-TILGsaRFP-EFKD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 166 TEQVNGAMASCQALKLDALVIIGGVTSNTDAAQLAEtfaeakCATKVVGVPVTLNGDLKnqFVETTVGFDTICkvnsqli 245
Cdd:PRK03202   79 EEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTE------HGIPVIGLPGTIDNDIA--GTDYTIGFDTAL------- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 246 sNVCTDAL-------SAEKYYYFIRMMGRKASHVALECALQSHPNMVILGEEVaaskltiFDItKQICDAVQARAEKDKY 318
Cdd:PRK03202  144 -NTAVEAIdrlrdtaSSHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVP-------FDI-EELCAKIKKGRERGKK 214

                         250       260
                  ....*....|....*....|....*..
gi 1002236984 319 HGVVLIPEGlVESIPELYALLQEIHGL 345
Cdd:PRK03202  215 HAIIVVAEG-VMPAEELAKEIEERTGL 240
PTZ00286 PTZ00286
6-phospho-1-fructokinase; Provisional
 87-331 1.68e-10

6-phospho-1-fructokinase; Provisional


Pssm-ID: 185539  Cd Length: 459  Bit Score: 63.52  E-value: 1.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  87 VRVGVVFCGRQSPGGHNVIWGLHEAIKAHNPNSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLG--RTKDQIR 164
Cdd:PTZ00286   88 VKAGIVTCGGLCPGLNVVIRELVMNLINNYGVKTIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGG-TILGssRGGFDPK 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 165 TteqvngaMAscQAL---KLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKnqFVETTVGFDTICKVN 241
Cdd:PTZ00286  167 V-------MV--DTLirhGINILFTLGGDGTHRGALAIYKELRRRKLNISVVGIPKTIDNDIP--IIDESFGFQTAVEEA 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 242 SQLISNVCTDALSAEKYYYFIRMMGRKASHVALECALQS-HPNMVILGEevaaskltiFDIT-KQICDAVQARAEKDKyH 319
Cdd:PTZ00286  236 QNAIRAAYVEAKSAKNGVGIVKLMGRDSGFIALHASVASaDVNVCLIPE---------FDIPlEGVLEYIEQRLQKKG-H 305

                         250
                  ....*....|..
gi 1002236984 320 GVVLIPEGLVES 331
Cdd:PTZ00286  306 CVIVVAEGAGQS 317
PRK14071 PRK14071
ATP-dependent 6-phosphofructokinase;
107-327 1.85e-10

ATP-dependent 6-phosphofructokinase;


Pssm-ID: 184487 [Multi-domain]  Cd Length: 360  Bit Score: 62.78  E-value: 1.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 107 GLHEAIKA------HNPNSKLIGFLGGSDGLLAQ--KTLEITDEVLSSYKNQGGyDMLGRT---------------KDqi 163
Cdd:PRK14071   18 GLNAVIRAvvhrarGTYGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGG-TILGTTnkgdpfafpmpdgslRD-- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 164 RTTEQVNGAmascQALKLDALVIIGGVTSNTDAAQLAEtfaeaKCATKVVGVPVTLNGDLKnqFVETTVGFDTickvnsq 243
Cdd:PRK14071   95 RSQEIIDGY----HSLGLDALIGIGGDGSLAILRRLAQ-----QGGINLVGIPKTIDNDVG--ATEVSIGFDT------- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 244 lISNVCTDAL------SAEKYYYFI-RMMGRKASHVALECALQSHPNmVILGEEVAaskLTIFDITKQICDavqaRAEKD 316
Cdd:PRK14071  157 -AVNIATEALdrlhftAASHNRVMIlEVMGRDAGHIALAAGIAGGAD-VILIPEIP---YTLENVCKKIRE----RQEEG 227

                         250
                  ....*....|.
gi 1002236984 317 KYHGVVLIPEG 327
Cdd:PRK14071  228 KNFCLVVVSEA 238
PLN02884 PLN02884
6-phosphofructokinase
 87-280 2.85e-08

6-phosphofructokinase


Pssm-ID: 178472 [Multi-domain]  Cd Length: 411  Bit Score: 56.36  E-value: 2.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  87 VRVGVVFCGRQSPGGHNVI---------WGLHEAIKAHNpnskliGFLGGSDGLLAQktLEITDEVLSSYKNQGGyDMLG 157
Cdd:PLN02884   54 VKAAIVTCGGLCPGLNDVIrqivftleiYGVKNIVGIPF------GYRGFFEKGLSE--MPLSRKVVQNIHLSGG-SLLG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 158 RTKDQIRTTEQVNgamaSCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLknQFVETTVGFDTI 237
Cdd:PLN02884  125 VSRGGAKTSDIVD----SIEARGINMLFVLGGNGTHAGANAIHNECRKRKMKVSVVGVPKTIDNDI--LLMDKTFGFDTA 198

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1002236984 238 CKVNSQLISNVCTDALSAEKYYYFIRMMGRKASHVALECALQS 280
Cdd:PLN02884  199 VEEAQRAINSAYIEAHSAYHGIGLVKLMGRSSGFIAMHASLAS 241
PLN02564 PLN02564
6-phosphofructokinase
 87-280 8.69e-07

6-phosphofructokinase


Pssm-ID: 178178  Cd Length: 484  Bit Score: 51.67  E-value: 8.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984  87 VRVGVVFCGRQSPGGHNVI----WGLHEAIKAhnpnSKLIGFLGGSDGLLAQKTLEITDEVLSSYKNQGGyDMLGRTKDQ 162
Cdd:PLN02564   88 VRACIVTCGGLCPGLNTVIreivCGLSYMYGV----TRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGG-TILGTSRGG 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 163 IRTTEQVNgamaSCQALKLDALVIIGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGDLKnqFVETTVGFDTICKVNS 242
Cdd:PLN02564  163 HDTSKIVD----SIQDRGINQVYIIGGDGTQKGASVIYEEIRRRGLKVAVAGIPKTIDNDIP--VIDKSFGFDTAVEEAQ 236

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1002236984 243 QLISNVCTDALSAEKYYYFIRMMGRKASHVALECALQS 280
Cdd:PLN02564  237 RAINAAHVEAESVENGIGLVKLMGRYSGFIAMYATLAS 274
PRK06555 PRK06555
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
 117-222 7.96e-04

pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated


Pssm-ID: 180620 [Multi-domain]  Cd Length: 403  Bit Score: 42.30  E-value: 7.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002236984 117 PNSKLIGFLGGSDGLLAQKTLEITDEV------LSSYknqGGYDM------LGRTKDQIR---TTEQVNGAMASCQALKL 181
Cdd:PRK06555   34 PEVEIIAYRSGYQGLLLGDSIEITPAVranaglLHRY---GGSPIgnsrvkLTNVADCVKrglVKEGENPLKVAAERLAA 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1002236984 182 DALVI---IGGVTSNTDAAQLAETFAEAKCATKVVGVPVTLNGD 222
Cdd:PRK06555  111 DGVDIlhtIGGDDTNTTAADLAAYLAENGYDLTVVGLPKTIDND 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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