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Conserved domains on  [gi|1034670445|ref|XP_016870328|]
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centlein isoform X1 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
131-793 1.39e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 1.39e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  131 KRLQVTNPDLTQVVSLVVEREKQ----------------KSEAKDRKVLEIL----QVKDAKIQEFEQRESVLKQEINDL 190
Cdd:TIGR02168  179 RKLERTRENLDRLEDILNELERQlkslerqaekaerykeLKAELRELELALLvlrlEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  191 VKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQ 267
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILrerLANLERQLEELEAQLEELESKLDELAEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  268 EAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ----ELQNLYKQNST 343
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIErleaRLERLEDRRER 418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  344 HTAQQAELIQQLQVLNMDTQKV-----------LRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQL 412
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAeleeleeeleeLQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  413 LQKEQENAKLKEKLQESQGAPLPLPQ-----ESDPDYSA----------------------------------------- 446
Cdd:TIGR02168  499 ENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAaieaalggrlqavvvenlnaakkaiaflkqnelgrvtflpl 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  447 --------QVPHRPSLSSLETLMVSQKSEIEY--------------------LQEKLKIANE-KLSENISANKG--FSRK 495
Cdd:TIGR02168  579 dsikgteiQGNDREILKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddLDNALELAKKlRPGYRIVTLDGdlVRPG 658
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  496 SIMTSAEGKHKEPPVKRSRSLspkssftdsEEL-QKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYR 574
Cdd:TIGR02168  659 GVITGGSAKTNSSILERRREI---------EELeEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  575 AVKEQLKQWEEgsgmTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMI----QKMNLEEELDELKVHISIDKAAI 650
Cdd:TIGR02168  730 ALRKDLARLEA----EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAeaeaEIEELEAQIEQLKEELKALREAL 805
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  651 QELNRCVAERREEQL-FRSGEDDEVKRSTPEKNGKEMLEQTLQKVTElenRLKSFEKRSRKLKEGNKKLMKENDFLKSLL 729
Cdd:TIGR02168  806 DELRAELTLLNEEAAnLRERLESLERRIAATERRLEDLEEQIEELSE---DIESLAAEIEELEELIEELESELEALLNER 882
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034670445  730 KQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 793
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
PTZ00121 super family cl31754
MAEBL; Provisional
510-1357 7.24e-06

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 7.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  510 VKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAhEKRKERLQMLQTNYRAvkEQLKQWEEGSGM 589
Cdd:PTZ00121  1066 VGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEA-RKAEEAKKKAEDARKA--EEARKAEDARKA 1142
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  590 TEIRKIKRADPQQLRQEDSDAVWNELAYfKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSG 669
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAE 1221
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  670 ED---------DEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKEndflkslLKQQQEDTETRE 740
Cdd:PTZ00121  1222 DAkkaeavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE-------LKKAEEKKKADE 1294
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  741 KELEQIIKGSKDVEKENTELQvKISELETEVTSLRRQvaeANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYD 820
Cdd:PTZ00121  1295 AKKAEEKKKADEAKKKAEEAK-KADEAKKKAEEAKKK---ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  821 CKTTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDG 900
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  901 KDQKESDPTEDSQTQGKEIVQTYlNIDGKTPKDYFHDKNAKKPTFQKKNC----KMQKSSHTAVPTRVNREKYKNITAQK 976
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKKKAdeakKAAEAKKKADEAKKAEEAKKADEAKK 1529
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  977 SSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLK 1056
Cdd:PTZ00121  1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1057 KLESSSEITSLAEEnsqvtfpriQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKI 1136
Cdd:PTZ00121  1610 EEAKKAEEAKIKAE---------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1137 SRMERDI-----TMKRHLIEDLKFRQ-KVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYE 1210
Cdd:PTZ00121  1681 KKAEEDEkkaaeALKKEAEEAKKAEElKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1211 QMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETaaSKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKalakE 1290
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV--DKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK----E 1834
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034670445 1291 LQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1357
Cdd:PTZ00121  1835 VADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
131-793 1.39e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 1.39e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  131 KRLQVTNPDLTQVVSLVVEREKQ----------------KSEAKDRKVLEIL----QVKDAKIQEFEQRESVLKQEINDL 190
Cdd:TIGR02168  179 RKLERTRENLDRLEDILNELERQlkslerqaekaerykeLKAELRELELALLvlrlEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  191 VKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQ 267
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILrerLANLERQLEELEAQLEELESKLDELAEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  268 EAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ----ELQNLYKQNST 343
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIErleaRLERLEDRRER 418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  344 HTAQQAELIQQLQVLNMDTQKV-----------LRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQL 412
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAeleeleeeleeLQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  413 LQKEQENAKLKEKLQESQGAPLPLPQ-----ESDPDYSA----------------------------------------- 446
Cdd:TIGR02168  499 ENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAaieaalggrlqavvvenlnaakkaiaflkqnelgrvtflpl 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  447 --------QVPHRPSLSSLETLMVSQKSEIEY--------------------LQEKLKIANE-KLSENISANKG--FSRK 495
Cdd:TIGR02168  579 dsikgteiQGNDREILKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddLDNALELAKKlRPGYRIVTLDGdlVRPG 658
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  496 SIMTSAEGKHKEPPVKRSRSLspkssftdsEEL-QKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYR 574
Cdd:TIGR02168  659 GVITGGSAKTNSSILERRREI---------EELeEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  575 AVKEQLKQWEEgsgmTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMI----QKMNLEEELDELKVHISIDKAAI 650
Cdd:TIGR02168  730 ALRKDLARLEA----EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAeaeaEIEELEAQIEQLKEELKALREAL 805
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  651 QELNRCVAERREEQL-FRSGEDDEVKRSTPEKNGKEMLEQTLQKVTElenRLKSFEKRSRKLKEGNKKLMKENDFLKSLL 729
Cdd:TIGR02168  806 DELRAELTLLNEEAAnLRERLESLERRIAATERRLEDLEEQIEELSE---DIESLAAEIEELEELIEELESELEALLNER 882
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034670445  730 KQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 793
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
154-748 2.38e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 2.38e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  154 KSEAKDRKVLEIL---QVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQ 230
Cdd:COG1196    219 KEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  231 NKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALS 307
Cdd:COG1196    299 RLEQDIARLeerRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  308 LQLSNKQTELIQKDMDITLVRKELQELQnlyKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLynel 387
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELE---EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE---- 451
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  388 hicfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQE--SQGAPLPLPQESDPDYSAQVPhRPSLSSLETLMVSQK 465
Cdd:COG1196    452 ----AELEEEEEALLELLAELLEEAALLEAALAELLEELAEaaARLLLLLEAEADYEGFLEGVK-AALLLAGLRGLAGAV 526
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  466 SEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKE-----------PPVKRSRSLSPKSSFTDSEELQKLRKA 534
Cdd:COG1196    527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVAS 606
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  535 ERKIENL-EKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWN 613
Cdd:COG1196    607 DLREADArYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  614 ELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEqtlqk 693
Cdd:COG1196    687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD----- 761
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034670445  694 VTELENRLKSFEKRSRKLKEGN-------KKLMKENDFLKSllkqQQEDTETREKELEQIIK 748
Cdd:COG1196    762 LEELERELERLEREIEALGPVNllaieeyEELEERYDFLSE----QREDLEEARETLEEAIE 819
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
450-797 7.90e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 7.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  450 HRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSEnisankgfsrksimTSAEGKHKEPPVKRSRSLSPKSS--FTDSEE 527
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEE--------------LKKEIEELEEKVKELKELKEKAEeyIKLSEF 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  528 LQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQED 607
Cdd:PRK03918   302 YEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRL 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  608 SDavwNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQlfrsGEDDEVKRSTPEKNGKEML 687
Cdd:PRK03918   382 TG---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAK----GKCPVCGRELTEEHRKELL 454
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  688 EQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTE---LQVKI 764
Cdd:PRK03918   455 EEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEyekLKEKL 534
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1034670445  765 SELETEVTSLRRQVAEANALRNENEELINPMEK 797
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDE 567
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
131-780 8.00e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 8.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  131 KRLQVTNPDLTQVVSLVVEREKQ-KSEAKDRKVLEILQVKDAKIQEFEQRESVLKQeiNDLVKRKIAVDEENAFLRKEFS 209
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY--LKLNEERIDLLQELLRDEQEEI 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  210 DLEKKFKDKSQEIKDTKECVQNKEEQnrlVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNL 289
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEK---EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  290 IEARKEVE-----------VSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVL 358
Cdd:pfam02463  331 KKEKEEIEelekelkeleiKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  359 N------MDTQKVLRNQEDVHTAESisyQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGA 432
Cdd:pfam02463  411 LelarqlEDLLKEEKKEELEILEEE---EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  433 PLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKS----EIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEP 508
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGgriiSAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLV 567
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  509 PVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSG 588
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  589 MTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERRE-EQLFR 667
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEElLADRV 727
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  668 SGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQII 747
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807
                          650       660       670
                   ....*....|....*....|....*....|...
gi 1034670445  748 KGSKDVEKENTELQVKISELETEVTSLRRQVAE 780
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELAL 840
PTZ00121 PTZ00121
MAEBL; Provisional
510-1357 7.24e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 7.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  510 VKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAhEKRKERLQMLQTNYRAvkEQLKQWEEGSGM 589
Cdd:PTZ00121  1066 VGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEA-RKAEEAKKKAEDARKA--EEARKAEDARKA 1142
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  590 TEIRKIKRADPQQLRQEDSDAVWNELAYfKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSG 669
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAE 1221
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  670 ED---------DEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKEndflkslLKQQQEDTETRE 740
Cdd:PTZ00121  1222 DAkkaeavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE-------LKKAEEKKKADE 1294
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  741 KELEQIIKGSKDVEKENTELQvKISELETEVTSLRRQvaeANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYD 820
Cdd:PTZ00121  1295 AKKAEEKKKADEAKKKAEEAK-KADEAKKKAEEAKKK---ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  821 CKTTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDG 900
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  901 KDQKESDPTEDSQTQGKEIVQTYlNIDGKTPKDYFHDKNAKKPTFQKKNC----KMQKSSHTAVPTRVNREKYKNITAQK 976
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKKKAdeakKAAEAKKKADEAKKAEEAKKADEAKK 1529
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  977 SSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLK 1056
Cdd:PTZ00121  1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1057 KLESSSEITSLAEEnsqvtfpriQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKI 1136
Cdd:PTZ00121  1610 EEAKKAEEAKIKAE---------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1137 SRMERDI-----TMKRHLIEDLKFRQ-KVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYE 1210
Cdd:PTZ00121  1681 KKAEEDEkkaaeALKKEAEEAKKAEElKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1211 QMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETaaSKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKalakE 1290
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV--DKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK----E 1834
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034670445 1291 LQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1357
Cdd:PTZ00121  1835 VADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
984-1273 3.56e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 48.28  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  984 LRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLaglrKEKEDLLK--KLESS 1061
Cdd:pfam10174  420 LKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL----KEKVSALQpeLTEKE 495
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1062 SEITSLAEensqvtfpriQVTSLSPS-RSMDLEMKQLQYKLKNATNELTKQSSNVKTLKfELLAKEEHIKEMHEKISRME 1140
Cdd:pfam10174  496 SSLIDLKE----------HASSLASSgLKKDSKLKSLEIAVEQKKEECSKLENQLKKAH-NAEEAVRTNPEINDRIRLLE 564
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1141 RDITMKR-----------HLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKvSIDSLKQRLNVAVKEKSQY 1209
Cdd:pfam10174  565 QEVARYKeesgkaqaeveRLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIK-HGQQEMKKKGAQLLEEARR 643
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034670445 1210 EQMYQKSK----------EELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLLLA 1273
Cdd:pfam10174  644 REDNLADNsqqlqleelmGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAA 717
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
529-1305 1.39e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  529 QKLRKAERKIENLEKALqlksqenDELRDAHEKRKERLQMLQ------TNYRAVKEQLKQWEEGSGMTEIRKIKRadpqq 602
Cdd:TIGR02168  172 ERRKETERKLERTRENL-------DRLEDILNELERQLKSLErqaekaERYKELKAELRELELALLVLRLEELRE----- 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  603 lrqedsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEqlfrsgeddevkrstpekn 682
Cdd:TIGR02168  240 -----------ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE------------------- 289
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  683 gkemLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQV 762
Cdd:TIGR02168  290 ----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA 365
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  763 KISELET--------------EVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKV 828
Cdd:TIGR02168  366 ELEELESrleeleeqletlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL 445
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  829 KFKAAKKNCSVGRHHTVLN---------------------------HSIKVMSNVFENLSKDG--WEDVSESSSDSEAQT 879
Cdd:TIGR02168  446 EEELEELQEELERLEEALEelreeleeaeqaldaaerelaqlqarlDSLERLQENLEGFSEGVkaLLKNQSGLSGILGVL 525
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  880 SQ------------------TLGTIIVETSQK-------ISPTEDGK---------DQKESDPTEDSQTQGKEIVQTYLN 925
Cdd:TIGR02168  526 SElisvdegyeaaieaalggRLQAVVVENLNAakkaiafLKQNELGRvtflpldsiKGTEIQGNDREILKNIEGFLGVAK 605
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  926 IDGKTPKDYfhdKNAKKPTFQkkNCKMQKSSHTAVPTRV-NREKYKNITAQ---------------KSSSNIILLRERII 989
Cdd:TIGR02168  606 DLVKFDPKL---RKALSYLLG--GVLVVDDLDNALELAKkLRPGYRIVTLDgdlvrpggvitggsaKTNSSILERRREIE 680
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  990 SLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAE 1069
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1070 ENSQVTFPRIQVTSLSPSRSMDlEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHL 1149
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1150 IEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEksqyeqmYQKSKEELEKKDLKLTL 1229
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE-------LEELSEELRELESKRSE 912
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034670445 1230 LVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLllanEKVEEFTTFVKALAKELQNDVHVVRRQIREL 1305
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1093-1292 1.12e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1093 EMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHE-------KISRMERDITMKRHLIEDLKFRQKVNLESNK 1165
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRRELEERLEELEEELA 326
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1166 SFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIE 1245
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1034670445 1246 TAASKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKALAKELQ 1292
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
131-793 1.39e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 1.39e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  131 KRLQVTNPDLTQVVSLVVEREKQ----------------KSEAKDRKVLEIL----QVKDAKIQEFEQRESVLKQEINDL 190
Cdd:TIGR02168  179 RKLERTRENLDRLEDILNELERQlkslerqaekaerykeLKAELRELELALLvlrlEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  191 VKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQ 267
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILrerLANLERQLEELEAQLEELESKLDELAEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  268 EAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ----ELQNLYKQNST 343
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIErleaRLERLEDRRER 418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  344 HTAQQAELIQQLQVLNMDTQKV-----------LRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQL 412
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAeleeleeeleeLQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  413 LQKEQENAKLKEKLQESQGAPLPLPQ-----ESDPDYSA----------------------------------------- 446
Cdd:TIGR02168  499 ENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAaieaalggrlqavvvenlnaakkaiaflkqnelgrvtflpl 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  447 --------QVPHRPSLSSLETLMVSQKSEIEY--------------------LQEKLKIANE-KLSENISANKG--FSRK 495
Cdd:TIGR02168  579 dsikgteiQGNDREILKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddLDNALELAKKlRPGYRIVTLDGdlVRPG 658
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  496 SIMTSAEGKHKEPPVKRSRSLspkssftdsEEL-QKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYR 574
Cdd:TIGR02168  659 GVITGGSAKTNSSILERRREI---------EELeEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  575 AVKEQLKQWEEgsgmTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMI----QKMNLEEELDELKVHISIDKAAI 650
Cdd:TIGR02168  730 ALRKDLARLEA----EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAeaeaEIEELEAQIEQLKEELKALREAL 805
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  651 QELNRCVAERREEQL-FRSGEDDEVKRSTPEKNGKEMLEQTLQKVTElenRLKSFEKRSRKLKEGNKKLMKENDFLKSLL 729
Cdd:TIGR02168  806 DELRAELTLLNEEAAnLRERLESLERRIAATERRLEDLEEQIEELSE---DIESLAAEIEELEELIEELESELEALLNER 882
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034670445  730 KQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 793
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
142-791 5.32e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 5.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  142 QVVSLVVEREKQKSEAKD-RKVLEILQVKDAKIQEfeqRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKfkdksq 220
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEElEREIEEERKRRDKLTE---EYAELKEELEDLRAELEEVDKEFAETRDELKDYREK------ 393
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  221 eikdtKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQ 300
Cdd:TIGR02169  394 -----LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  301 SKYNALSLQLSNKQTELIQKdmditlvRKELQELQnlykqnsthtaQQAELIQQLQVLNMDTQKVLR-NQEDVH--TAES 377
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKL-------QRELAEAE-----------AQARASEERVRGGRAVEEVLKaSIQGVHgtVAQL 530
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  378 ISYQKLYnelHICFETTKSNEamlrqsvtnLQDQLLQKEQENAKLKEKLQESQGAP---LPLPQESDPDYSAQVPHRPSL 454
Cdd:TIGR02169  531 GSVGERY---ATAIEVAAGNR---------LNNVVVEDDAVAKEAIELLKRRKAGRatfLPLNKMRDERRDLSILSEDGV 598
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  455 SSLETLMVSQKSEIEYLQeKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPP---VKRSRSLSPKSSFT--DSEELQ 529
Cdd:TIGR02169  599 IGFAVDLVEFDPKYEPAF-KYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKSgamTGGSRAPRGGILFSrsEPAELQ 677
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  530 KLRKAERKIENLEKALQ--LKSQEN------DELRDAHEKRKE---RLQMLQTNYRAVKEQLKQWEEgsgmtEIRKIKRA 598
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQseLRRIENrldelsQELSDASRKIGEiekEIEQLEQEEEKLKERLEELEE-----DLSSLEQE 752
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  599 dpqqlrqedSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAI--QELNRCVAERREEQLFRSGEDDEVKR 676
Cdd:TIGR02169  753 ---------IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqAELSKLEEEVSRIEARLREIEQKLNR 823
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  677 STPEKNGKEMLEQTLQ-KVTELENRLKSFEKRsrkLKEGNKKLMKendfLKSLLKQQQEDTETREKELEQIIKGSKDVEK 755
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQeQRIDLKEQIKSIEKE---IENLNGKKEE----LEEELEELEAALRDLESRLGDLKKERDELEA 896
                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1034670445  756 ENTELQVKISELETEVTSLRRQVAEANA-LRNENEEL 791
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAkLEALEEEL 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
154-748 2.38e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 2.38e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  154 KSEAKDRKVLEIL---QVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQ 230
Cdd:COG1196    219 KEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  231 NKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALS 307
Cdd:COG1196    299 RLEQDIARLeerRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  308 LQLSNKQTELIQKDMDITLVRKELQELQnlyKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLynel 387
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELE---EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE---- 451
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  388 hicfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQE--SQGAPLPLPQESDPDYSAQVPhRPSLSSLETLMVSQK 465
Cdd:COG1196    452 ----AELEEEEEALLELLAELLEEAALLEAALAELLEELAEaaARLLLLLEAEADYEGFLEGVK-AALLLAGLRGLAGAV 526
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  466 SEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKE-----------PPVKRSRSLSPKSSFTDSEELQKLRKA 534
Cdd:COG1196    527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVAS 606
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  535 ERKIENL-EKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWN 613
Cdd:COG1196    607 DLREADArYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  614 ELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEqtlqk 693
Cdd:COG1196    687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD----- 761
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034670445  694 VTELENRLKSFEKRSRKLKEGN-------KKLMKENDFLKSllkqQQEDTETREKELEQIIK 748
Cdd:COG1196    762 LEELERELERLEREIEALGPVNllaieeyEELEERYDFLSE----QREDLEEARETLEEAIE 819
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
241-808 3.10e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 3.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  241 KNLEEENKKLsTRCTDLLNDLEK-----------------LRKQEAHLRKEKYSTDakIKTFEDNLIEARKEVEVSQSKY 303
Cdd:TIGR02168  179 RKLERTRENL-DRLEDILNELERqlkslerqaekaerykeLKAELRELELALLVLR--LEELREELEELQEELKEAEEEL 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  304 NALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQnstHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKL 383
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYA---LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  384 ynelhicfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDPDYSAQVPHRPSLSSLETLMVS 463
Cdd:TIGR02168  333 --------DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  464 QKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRslspkssftDSEELQKLRKAERKIENLEK 543
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE---------LERLEEALEELREELEEAEQ 475
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  544 ALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGM---------------TEIRKIKRADPQQLRQEDS 608
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlselisvdegyeAAIEAALGGRLQAVVVENL 555
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  609 DAVWNELAYFKRENQ------------------ELMIQKMNLEEELDELKVHISIDKAA----------------IQELN 654
Cdd:TIGR02168  556 NAAKKAIAFLKQNELgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNAL 635
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  655 RCVAERREEQLF-------------RSGEDDEVKRSTPE-----KNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNK 716
Cdd:TIGR02168  636 ELAKKLRPGYRIvtldgdlvrpggvITGGSAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELE 715
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  717 KLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPME 796
Cdd:TIGR02168  716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795
                          650
                   ....*....|..
gi 1034670445  797 KSHQSADRAKSE 808
Cdd:TIGR02168  796 EELKALREALDE 807
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
525-783 3.27e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 3.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  525 SEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMT----------EIRK 594
Cdd:TIGR02169  226 YELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvkekigeleaEIAS 305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  595 IKRA-DPQQLRQEDSDA-----------VWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERRE 662
Cdd:TIGR02169  306 LERSiAEKERELEDAEErlakleaeidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  663 EQLFRSGEDDEVKRSTPEKNGK-----EMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTE 737
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKREldrlqEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1034670445  738 TREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANA 783
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
528-805 6.33e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 6.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  528 LQKLRKAERKIENLEKALQLKSQENDELR---DAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLR 604
Cdd:COG1196    231 LLKLRELEAELEELEAELEELEAELEELEaelAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  605 QEDSDAvwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRStpEKNGK 684
Cdd:COG1196    311 RRELEE---RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE--LEELA 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  685 EMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKI 764
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1034670445  765 SELETEVTSLRRQVAEANALRNEN---EELINPMEKSHQSADRA 805
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAaarLLLLLEAEADYEGFLEG 509
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
450-797 7.90e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 7.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  450 HRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSEnisankgfsrksimTSAEGKHKEPPVKRSRSLSPKSS--FTDSEE 527
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEE--------------LKKEIEELEEKVKELKELKEKAEeyIKLSEF 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  528 LQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQED 607
Cdd:PRK03918   302 YEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRL 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  608 SDavwNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQlfrsGEDDEVKRSTPEKNGKEML 687
Cdd:PRK03918   382 TG---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAK----GKCPVCGRELTEEHRKELL 454
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  688 EQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTE---LQVKI 764
Cdd:PRK03918   455 EEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEyekLKEKL 534
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1034670445  765 SELETEVTSLRRQVAEANALRNENEELINPMEK 797
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDE 567
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
526-808 5.26e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 5.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  526 EELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEgsgmteirkikradpqqlrq 605
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-------------------- 302
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  606 edsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQlfrsgeddevkrstpeKNGKE 685
Cdd:COG1196    303 --------DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL----------------EEAEA 358
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  686 MLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKIS 765
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1034670445  766 ELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSE 808
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
131-780 8.00e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 8.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  131 KRLQVTNPDLTQVVSLVVEREKQ-KSEAKDRKVLEILQVKDAKIQEFEQRESVLKQeiNDLVKRKIAVDEENAFLRKEFS 209
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY--LKLNEERIDLLQELLRDEQEEI 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  210 DLEKKFKDKSQEIKDTKECVQNKEEQnrlVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNL 289
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEK---EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  290 IEARKEVE-----------VSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVL 358
Cdd:pfam02463  331 KKEKEEIEelekelkeleiKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  359 N------MDTQKVLRNQEDVHTAESisyQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGA 432
Cdd:pfam02463  411 LelarqlEDLLKEEKKEELEILEEE---EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  433 PLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKS----EIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEP 508
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGgriiSAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLV 567
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  509 PVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSG 588
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  589 MTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERRE-EQLFR 667
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEElLADRV 727
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  668 SGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQII 747
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807
                          650       660       670
                   ....*....|....*....|....*....|...
gi 1034670445  748 KGSKDVEKENTELQVKISELETEVTSLRRQVAE 780
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELAL 840
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
103-663 1.04e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  103 QLLEEELSSLKEELALCQADKEfvwslwkRLQVTNPDLTQVVSLVVEREkQKSEAKDRKVLEILQVKDAKIQEFEQRESV 182
Cdd:COG1196    249 EELEAELEELEAELAELEAELE-------ELRLELEELELELEEAQAEE-YELLAELARLEQDIARLEERRRELEERLEE 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  183 LKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLST---RCTDLLN 259
Cdd:COG1196    321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEalrAAAELAA 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  260 DLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYK 339
Cdd:COG1196    401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  340 QNSTHTAQQAELIQQLQvlNMDTQKVLRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVT-NLQDQLLQKEQE 418
Cdd:COG1196    481 ELLEELAEAAARLLLLL--EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAaALQNIVVEDDEV 558
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  419 NAKLKEKLQESQ-GAPLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSI 497
Cdd:COG1196    559 AAAAIEYLKAAKaGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  498 MTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVK 577
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  578 EQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWNELA-YFKRENQELMIQKmnLEEELDELKvhiSIDKAAIQELNRc 656
Cdd:COG1196    719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPePPDLEELERELER--LEREIEALG---PVNLLAIEEYEE- 792

                   ....*..
gi 1034670445  657 VAERREE 663
Cdd:COG1196    793 LEERYDF 799
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
170-741 1.65e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 1.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  170 DAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKkfkdksqeikdTKECVQNKEEQNRLV---IKNLEEE 246
Cdd:PRK03918   192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE-----------LKEEIEELEKELESLegsKRKLEEK 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  247 NKKLSTRCTDLLNDLEKLRKQEAHLR--KEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDI 324
Cdd:PRK03918   261 IRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL 340
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  325 TLVRKELQELQNLYkqnsthtaqqAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLYNELhicfETTKSNEAMLRQS 404
Cdd:PRK03918   341 EELKKKLKELEKRL----------EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL----EELEKAKEEIEEE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  405 VTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPqesdpdysaqVPHRP-SLSSLETLMVSQKSEIEYLQEKLKIANEKLS 483
Cdd:PRK03918   407 ISKITARIGELKKEIKELKKAIEELKKAKGKCP----------VCGRElTEEHRKELLEEYTAELKRIEKELKEIEEKER 476
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  484 EnISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIEnlEKALQLKSQENDELRDAhekrk 563
Cdd:PRK03918   477 K-LRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLK--EKLIKLKGEIKSLKKEL----- 548
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  564 ERLQMLQTNYRAVKEQLKQWEE--GSGMTEIRKIKRADPQQLRQEDSdavwnELAYFKRENQELMIQKMNLEEELDELKV 641
Cdd:PRK03918   549 EKLEELKKKLAELEKKLDELEEelAELLKELEELGFESVEELEERLK-----ELEPFYNEYLELKDAEKELEREEKELKK 623
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  642 HISIDKAAIQELNRCVAERRE-----EQLFRSGEDDEVKRSTPEKNGKEM-LEQTLQKVTELENRLKSFEKRSRKLKEGN 715
Cdd:PRK03918   624 LEEELDKAFEELAETEKRLEElrkelEELEKKYSEEEYEELREEYLELSReLAGLRAELEELEKRREEIKKTLEKLKEEL 703
                          570       580
                   ....*....|....*....|....*.
gi 1034670445  716 KKLMKENDFLKSLLKQQQEDTETREK 741
Cdd:PRK03918   704 EEREKAKKELEKLEKALERVEELREK 729
PTZ00121 PTZ00121
MAEBL; Provisional
151-717 6.71e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 6.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  151 EKQKSEAKDRKVLEILQVKDAKIQEFEQRESVLK-------QEINDLVKRKIAVDEENAFLRKEFSDLEKK--------- 214
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeearkaDELKKAEEKKKADEAKKAEEKKKADEAKKKaeeakkade 1319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  215 FKDKSQEIKDTKECVQNKEEQNRLV--IKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDnliEA 292
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD---EA 1396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  293 RKEVEVSQSKYNALslqlsNKQTELIQKDMDITLVRKELQELQNLYKQnsTHTAQQAELIQQLQVLNMDTQKVLRNQEDV 372
Cdd:PTZ00121  1397 KKKAEEDKKKADEL-----KKAAAAKKKADEAKKKAEEKKKADEAKKK--AEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  373 HTAESISYQklynelhiCFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDPDYSAQVPHRP 452
Cdd:PTZ00121  1470 KKADEAKKK--------AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK 1541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  453 SLSSLETLMVSQKSEIEYLQEKLKiANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKrsrsLSPKSSFTDSEELQKLR 532
Cdd:PTZ00121  1542 AEEKKKADELKKAEELKKAEEKKK-AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK----LYEEEKKMKAEEAKKAE 1616
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  533 KAERKIENLEKA-------LQLKSQENDELRDAHEKRKERlqmLQTNYRAVKEQLKQWEEGSGMTEIRKI---KRADPQQ 602
Cdd:PTZ00121  1617 EAKIKAEELKKAeeekkkvEQLKKKEAEEKKKAEELKKAE---EENKIKAAEEAKKAEEDKKKAEEAKKAeedEKKAAEA 1693
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  603 LRQEDSDAVWNELAYFKRENQELMIQKMNLEEE-----LDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRS 677
Cdd:PTZ00121  1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEenkikAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1034670445  678 TPEKNG---KEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKK 717
Cdd:PTZ00121  1774 RKEKEAvieEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
PTZ00121 PTZ00121
MAEBL; Provisional
510-1357 7.24e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 7.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  510 VKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAhEKRKERLQMLQTNYRAvkEQLKQWEEGSGM 589
Cdd:PTZ00121  1066 VGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEA-RKAEEAKKKAEDARKA--EEARKAEDARKA 1142
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  590 TEIRKIKRADPQQLRQEDSDAVWNELAYfKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSG 669
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAE 1221
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  670 ED---------DEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKEndflkslLKQQQEDTETRE 740
Cdd:PTZ00121  1222 DAkkaeavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE-------LKKAEEKKKADE 1294
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  741 KELEQIIKGSKDVEKENTELQvKISELETEVTSLRRQvaeANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYD 820
Cdd:PTZ00121  1295 AKKAEEKKKADEAKKKAEEAK-KADEAKKKAEEAKKK---ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  821 CKTTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDG 900
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  901 KDQKESDPTEDSQTQGKEIVQTYlNIDGKTPKDYFHDKNAKKPTFQKKNC----KMQKSSHTAVPTRVNREKYKNITAQK 976
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKKKAdeakKAAEAKKKADEAKKAEEAKKADEAKK 1529
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  977 SSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLK 1056
Cdd:PTZ00121  1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1057 KLESSSEITSLAEEnsqvtfpriQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKI 1136
Cdd:PTZ00121  1610 EEAKKAEEAKIKAE---------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1137 SRMERDI-----TMKRHLIEDLKFRQ-KVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYE 1210
Cdd:PTZ00121  1681 KKAEEDEkkaaeALKKEAEEAKKAEElKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1211 QMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETaaSKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKalakE 1290
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV--DKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK----E 1834
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034670445 1291 LQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1357
Cdd:PTZ00121  1835 VADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
212-799 1.13e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  212 EKKFKDKSQEIKDTKECVQNKEEQnrlvIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIE 291
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKE----LKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  292 ARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKEL----QELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVLR 367
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIkkkeKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  368 NQEDVHTAESISYQKL-----YNELHICFETTKSNeamLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDP 442
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLsnlkkKIQKNKSLESQISE---LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK 264
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  443 DYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSENISANkgfsRKSIMTSAEGKHKEPPVKRSRSlspkssf 522
Cdd:TIGR04523  265 IKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE----LKSELKNQEKKLEEIQNQISQN------- 333
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  523 tdseeLQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQ 602
Cdd:TIGR04523  334 -----NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ 408
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  603 LRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPE-- 680
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQkq 488
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  681 ---KNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETRE----------------K 741
Cdd:TIGR04523  489 kelKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDfelkkenlekeideknK 568
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034670445  742 ELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSH 799
Cdd:TIGR04523  569 EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEN 626
PTZ00121 PTZ00121
MAEBL; Provisional
204-835 1.20e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  204 LRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENK-KLSTRCTDLLNDLEKLRKQEAHLRKE--KYSTDA 280
Cdd:PTZ00121  1072 LKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaEEAKKKAEDARKAEEARKAEDARKAEeaRKAEDA 1151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  281 KIKTFEDNLIEARKeVEVSQSKYNALSLQLSNKQTEL-----IQKDMDITLVrKELQELQNLYKQNSTHTAQQAELIQQL 355
Cdd:PTZ00121  1152 KRVEIARKAEDARK-AEEARKAEDAKKAEAARKAEEVrkaeeLRKAEDARKA-EAARKAEEERKAEEARKAEDAKKAEAV 1229
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  356 QvlnmDTQKVLRNQEDVHTAESISyqklYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLP 435
Cdd:PTZ00121  1230 K----KAEEAKKDAEEAKKAEEER----NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  436 LPQESDPDYSaqvphrpslssletlmvSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRS 515
Cdd:PTZ00121  1302 KKADEAKKKA-----------------EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  516 LSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHE-KRKERLQMLQTNYRAVKEQLKQWEEGSGMTEirK 594
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAE--E 1442
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  595 IKRADPQQLRQEDSDAVWN--ELAYFKRENQELMiQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGED- 671
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEakKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEa 1521
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  672 ---DEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKlmKENDFLKSLLKQQQEDTETREKELEQIIK 748
Cdd:PTZ00121  1522 kkaDEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK--KAEEDKNMALRKAEEAKKAEEARIEEVMK 1599
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  749 GSKDVEKENTELQVKISELETEVTSLRRqvaeANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKV 828
Cdd:PTZ00121  1600 LYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKK 1675

                   ....*..
gi 1034670445  829 KFKAAKK 835
Cdd:PTZ00121  1676 KAEEAKK 1682
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
592-823 2.75e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 2.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  592 IRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGED 671
Cdd:PRK03918   151 VRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  672 DEVKRSTPEKNGKEMLEQTLQK-VTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLlKQQQEDTETREKELEQIIKGS 750
Cdd:PRK03918   231 KELEELKEEIEELEKELESLEGsKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDEL 309
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034670445  751 KDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEEL---INPMEKSHQSADRAKSEMATMKVRSGRYDCKT 823
Cdd:PRK03918   310 REIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELekrLEELEERHELYEEAKAKKEELERLKKRLTGLT 385
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
984-1273 3.56e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 48.28  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  984 LRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLaglrKEKEDLLK--KLESS 1061
Cdd:pfam10174  420 LKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL----KEKVSALQpeLTEKE 495
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1062 SEITSLAEensqvtfpriQVTSLSPS-RSMDLEMKQLQYKLKNATNELTKQSSNVKTLKfELLAKEEHIKEMHEKISRME 1140
Cdd:pfam10174  496 SSLIDLKE----------HASSLASSgLKKDSKLKSLEIAVEQKKEECSKLENQLKKAH-NAEEAVRTNPEINDRIRLLE 564
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1141 RDITMKR-----------HLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKvSIDSLKQRLNVAVKEKSQY 1209
Cdd:pfam10174  565 QEVARYKeesgkaqaeveRLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIK-HGQQEMKKKGAQLLEEARR 643
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034670445 1210 EQMYQKSK----------EELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLLLA 1273
Cdd:pfam10174  644 REDNLADNsqqlqleelmGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAA 717
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
178-793 3.84e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.09  E-value: 3.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  178 QRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDL 257
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL 196
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  258 LNDLEKLRKQEAHLRKEKySTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNL 337
Cdd:TIGR04523  197 LKLELLLSNLKKKIQKNK-SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE 275
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  338 YKQNSTHTAQQAELIQQL--QVLNMDTQKVLRNQEDVHTaESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQK 415
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLksEISDLNNQKEQDWNKELKS-ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNS 354
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  416 EQENAKLKEKLQESQGAPLPLPQESDpdysaqvphrpslssletlmvSQKSEIEYLQEKLKIANEKLSENISANKGFSRK 495
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIEKLKKENQ---------------------SYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ 413
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  496 SIMTSAEGKHKEPPVKRSRslspkssftdseelQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRA 575
Cdd:TIGR04523  414 IKKLQQEKELLEKEIERLK--------------ETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK 479
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  576 VKEQLKQWEEgsgmteirkikradpqqlrqedsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNR 655
Cdd:TIGR04523  480 IKQNLEQKQK----------------------------ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  656 CVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQED 735
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034670445  736 TETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 793
Cdd:TIGR04523  612 ISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIK 669
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
156-808 7.16e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 7.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  156 EAKDRKVLEILQVKDakiqeFEQRESVLKQEINDLVKRKIAVDEenaFLRKEfSDLEKKFKDKSQEIKDTKECVQNKEEQ 235
Cdd:PRK03918   145 ESREKVVRQILGLDD-----YENAYKNLGEVIKEIKRRIERLEK---FIKRT-ENIEELIKEKEKELEEVLREINEISSE 215
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  236 NRLVIKNLEEENKKLStRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNAL-SLQLSNKQ 314
Cdd:PRK03918   216 LPELREELEKLEKEVK-ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkELKEKAEE 294
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  315 TELIQKDMDitlvrKELQELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVlrnqedvhtaesisyqklyNELHICFETT 394
Cdd:PRK03918   295 YIKLSEFYE-----EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-------------------EELKKKLKEL 350
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  395 KSNEAMLRQSVTNLQDqLLQKEQENAKLKEKLQESqgaplplpqesdpdysaqvphrpSLSSLETLMVSQKSEIEYLQEK 474
Cdd:PRK03918   351 EKRLEELEERHELYEE-AKAKKEELERLKKRLTGL-----------------------TPEKLEKELEELEKAKEEIEEE 406
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  475 LKIANEKLSEnISANKGFSRKSIMTSAEGKHKEPPVKRSrslspkssFTDSEELQKLRKAERKIENLEKALQLKSQENDE 554
Cdd:PRK03918   407 ISKITARIGE-LKKEIKELKKAIEELKKAKGKCPVCGRE--------LTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  555 LRdaheKRKERLQMLQTN------YRAVKEQLKQWEEGSGMTEIRKIKRAdpqqlrqedsdavWNELAYFKRENQELMIQ 628
Cdd:PRK03918   478 LR----KELRELEKVLKKeselikLKELAEQLKELEEKLKKYNLEELEKK-------------AEEYEKLKEKLIKLKGE 540
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  629 KMNLEEELDELKVHISiDKAAIQELNRCVAERREEQL-------FRSGEDDEVKRSTPEKNGKEMLEqTLQKVTELENRL 701
Cdd:PRK03918   541 IKSLKKELEKLEELKK-KLAELEKKLDELEEELAELLkeleelgFESVEELEERLKELEPFYNEYLE-LKDAEKELEREE 618
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  702 KSFEKRSRKLKEGNKKLMKENDFLKSLlkqqqedtetrEKELEQiiKGSKDVEKENTELQVKISELETEVTSLRRQVAEA 781
Cdd:PRK03918   619 KELKKLEEELDKAFEELAETEKRLEEL-----------RKELEE--LEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685
                          650       660
                   ....*....|....*....|....*..
gi 1034670445  782 NALRNENEELINPMEKSHQSADRAKSE 808
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKKE 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
259-428 8.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 8.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  259 NDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLY 338
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  339 kqnsthtaqqAELIQQLQVL-NMDTQKVLRNQEDVHTAESIS--YQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQK 415
Cdd:COG4942    107 ----------AELLRALYRLgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
                          170
                   ....*....|...
gi 1034670445  416 EQENAKLKEKLQE 428
Cdd:COG4942    177 EALLAELEEERAA 189
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
529-1305 1.39e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  529 QKLRKAERKIENLEKALqlksqenDELRDAHEKRKERLQMLQ------TNYRAVKEQLKQWEEGSGMTEIRKIKRadpqq 602
Cdd:TIGR02168  172 ERRKETERKLERTRENL-------DRLEDILNELERQLKSLErqaekaERYKELKAELRELELALLVLRLEELRE----- 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  603 lrqedsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEqlfrsgeddevkrstpekn 682
Cdd:TIGR02168  240 -----------ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE------------------- 289
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  683 gkemLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQV 762
Cdd:TIGR02168  290 ----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA 365
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  763 KISELET--------------EVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKV 828
Cdd:TIGR02168  366 ELEELESrleeleeqletlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL 445
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  829 KFKAAKKNCSVGRHHTVLN---------------------------HSIKVMSNVFENLSKDG--WEDVSESSSDSEAQT 879
Cdd:TIGR02168  446 EEELEELQEELERLEEALEelreeleeaeqaldaaerelaqlqarlDSLERLQENLEGFSEGVkaLLKNQSGLSGILGVL 525
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  880 SQ------------------TLGTIIVETSQK-------ISPTEDGK---------DQKESDPTEDSQTQGKEIVQTYLN 925
Cdd:TIGR02168  526 SElisvdegyeaaieaalggRLQAVVVENLNAakkaiafLKQNELGRvtflpldsiKGTEIQGNDREILKNIEGFLGVAK 605
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  926 IDGKTPKDYfhdKNAKKPTFQkkNCKMQKSSHTAVPTRV-NREKYKNITAQ---------------KSSSNIILLRERII 989
Cdd:TIGR02168  606 DLVKFDPKL---RKALSYLLG--GVLVVDDLDNALELAKkLRPGYRIVTLDgdlvrpggvitggsaKTNSSILERRREIE 680
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  990 SLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAE 1069
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1070 ENSQVTFPRIQVTSLSPSRSMDlEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHL 1149
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1150 IEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEksqyeqmYQKSKEELEKKDLKLTL 1229
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE-------LEELSEELRELESKRSE 912
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034670445 1230 LVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLllanEKVEEFTTFVKALAKELQNDVHVVRRQIREL 1305
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
129-356 2.45e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 2.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  129 LWKRLQVTNPDLTQVVSLVVEREKQKSEAKDRKVLEILQVKdAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEF 208
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE-AQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  209 SDLEKKFKDKSQEIKDTKECVQNKEEQ---NRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTF 285
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDiesLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034670445  286 EDNLIEARKEVEVSQSKYNALSLQLSN-KQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQ 356
Cdd:TIGR02168  907 ESKRSELRRELEELREKLAQLELRLEGlEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
526-664 3.48e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  526 EELQKLRKAERKIENLEKALQLKSQENDELRDAHEKR---------KERLQMLQTNYRAVKEQLKQWEEGsgMTEIRKIK 596
Cdd:COG4717     92 ELQEELEELEEELEELEAELEELREELEKLEKLLQLLplyqelealEAELAELPERLEELEERLEELREL--EEELEELE 169
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034670445  597 ------RADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQ 664
Cdd:COG4717    170 aelaelQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE 243
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
229-430 4.63e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 4.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  229 VQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQE--AHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNAL 306
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  307 SLQLSNKQTEL--IQKDMDITLVRKELQELQnlykqnsthtAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLY 384
Cdd:COG3206    246 RAQLGSGPDALpeLLQSPVIQQLRAQLAELE----------AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRIL 315
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1034670445  385 NELHICFETTKSNEAMLRQSVTNLQDQLL---QKEQENAKLKEKLQESQ 430
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVAR 364
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
584-1361 6.36e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 6.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  584 EEGSGMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEE----ELDELKVHISIDKAAIQELNRCVAE 659
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKAleyyQLKEKLELEEEYLLYLDYLKLNEER 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  660 RREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNK--------KLMKENDFLKSLLKQ 731
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEeelksellKLERRKVDDEEKLKE 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  732 QQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMAT 811
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  812 MKVRSGRYDCK----------TTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQ 881
Cdd:pfam02463  399 LKSEEEKEAQLllelarqledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  882 TLGTIIVETSQKISPTEDGKDQKESDPTEDSQTQGKEIVQTYLNiDGKTPKDYFHDKNAKKPTFQKKNCkmqksshTAVP 961
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG-RIISAHGRLGDLGVAVENYKVAIS-------TAVI 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  962 TRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTaeLSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLN 1041
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS--IAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1042 LDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFpriQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFE 1121
Cdd:pfam02463  629 LKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSE---VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1122 LLAKEEHIKEMHEKISRMERDITMKRHLI--EDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRL 1199
Cdd:pfam02463  706 QREKEELKKLKLEAEELLADRVQEAQDKIneELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK 785
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1200 NVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEI--ETAASKQLQELALQSEQVLEGAQKTLLLANEKV 1277
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIkeEELEELALELKEEQKLEKLAEEELERLEEEITK 865
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1278 EEFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1357
Cdd:pfam02463  866 EELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945

                   ....
gi 1034670445 1358 NDKE 1361
Cdd:pfam02463  946 DEKE 949
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
263-778 6.58e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.33  E-value: 6.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  263 KLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSL---QLSNKQTELIQKDMDITLVRKELQELQNLYK 339
Cdd:pfam05483   82 KLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFeneKVSLKLEEEIQENKDLIKENNATRHLCNLLK 161
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  340 QNSTHTAQQA--------ELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQ 411
Cdd:pfam05483  162 ETCARSAEKTkkyeyereETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQ 241
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  412 ----LLQKEQENAKLKEklqesqgaplplpqesdpdysaqvphrpslssLETLMVSQKSEIEYLQEKLKIANEKLSENIS 487
Cdd:pfam05483  242 vsllLIQITEKENKMKD--------------------------------LTFLLEESRDKANQLEEKTKLQDENLKELIE 289
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  488 ANKGFSRKSimtsaegkhKEPPVKRSRSLSPKSSFTDSEEL------QKLRKAERKIENLEKALQLKSQENDELRDAHEK 561
Cdd:pfam05483  290 KKDHLTKEL---------EDIKMSLQRSMSTQKALEEDLQIatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCS 360
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  562 RKERLQMLQTNYRAVKEQLKQWEegsgMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKv 641
Cdd:pfam05483  361 LEELLRTEQQRLEKNEDQLKIIT----MELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELK- 435
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  642 hisidkAAIQELNRCVAERREEQlfrsgEDDEVKRSTPEKNGKEMLEQTLQKVTELEN-RLKSFE--KRSRKLKEGNKKL 718
Cdd:pfam05483  436 ------GKEQELIFLLQAREKEI-----HDLEIQLTAIKTSEEHYLKEVEDLKTELEKeKLKNIEltAHCDKLLLENKEL 504
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  719 MKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQV 778
Cdd:pfam05483  505 TQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEV 564
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
173-359 6.85e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.24  E-value: 6.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  173 IQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQnrlvIKNLEEENKKLST 252
Cdd:TIGR04523  351 LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ----IKKLQQEKELLEK 426
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  253 RCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ 332
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKK 506
                          170       180
                   ....*....|....*....|....*..
gi 1034670445  333 ELQNlykQNSTHTAQQAELIQQLQVLN 359
Cdd:TIGR04523  507 ELEE---KVKDLTKKISSLKEKIEKLE 530
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
502-787 7.88e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.88  E-value: 7.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  502 EGKHKEPPVKRSRSLSPKSSFTDSEelqklrkAERKIENLEKALQLKsQENDELRDAHEKRKERLQMLQTnyravkeqlk 581
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEE-------IERYEEQREQARETR-DEADEVLEEHEERREELETLEA---------- 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  582 qweegsgmtEIRKIkradpqqlrQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQElnrcVAERR 661
Cdd:PRK02224   259 ---------EIEDL---------RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEA----VEARR 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  662 EEQlfrSGEDDEVKRStpekngkemLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETR-- 739
Cdd:PRK02224   317 EEL---EDRDEELRDR---------LEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRre 384
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034670445  740 -----EKELEQIIKG--------------SKDVEKENTELQVKISELETEVTSLRRQVAEANALRNE 787
Cdd:PRK02224   385 eieelEEEIEELRERfgdapvdlgnaedfLEELREERDELREREAELEATLRTARERVEEAEALLEA 451
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
1037-1304 9.72e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 43.76  E-value: 9.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1037 IKKLN-LDLAGLRKEKEDLLKKLESSS--EITSLAEEnsqvtfprIQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSS 1113
Cdd:PRK05771     3 PVRMKkVLIVTLKSYKDEVLEALHELGvvHIEDLKEE--------LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLRE 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1114 NVKTLKFELLAK------------EEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLE-----SNKSFSEMLQNLDK 1176
Cdd:PRK05771    75 EKKKVSVKSLEElikdveeelekiEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDlslllGFKYVSVFVGTVPE 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1177 KVKTLTEECSNKKVS--IDSLKQRLNVA-VKEKSQYEQMYQ----------------KSKEELEKKDLKLTLLVSRISET 1237
Cdd:PRK05771   155 DKLEELKLESDVENVeyISTDKGYVYVVvVVLKELSDEVEEelkklgferleleeegTPSELIREIKEELEEIEKERESL 234
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1238 ESAMAEIetaaSKQLQELALQSEQVLEG-AQKTLLLANEK-------------VEEFTTFVKALAKELQNDVHVVRRQIR 1303
Cdd:PRK05771   235 LEELKEL----AKKYLEELLALYEYLEIeLERAEALSKFLktdktfaiegwvpEDRVKKLKELIDKATGGSAYVEFVEPD 310

                   .
gi 1034670445 1304 E 1304
Cdd:PRK05771   311 E 311
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1093-1292 1.12e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1093 EMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHE-------KISRMERDITMKRHLIEDLKFRQKVNLESNK 1165
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRRELEERLEELEEELA 326
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1166 SFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIE 1245
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1034670445 1246 TAASKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKALAKELQ 1292
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
157-320 1.38e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 1.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  157 AKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQN 236
Cdd:COG1579      3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  237 RLVIKN-----LEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLS 311
Cdd:COG1579     83 GNVRNNkeyeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162

                   ....*....
gi 1034670445  312 NKQTELIQK 320
Cdd:COG1579    163 AEREELAAK 171
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1122-1357 1.42e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1122 LLAKEEHIKEMHEKISRMERDITMKRHLIEDLKfrqkvnlesnKSFSEMLQNLDKKVKTLTEecsnKKVSIDSLKQRLNV 1201
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELR----------KELEELEEELEQLRKELEE----LSRQISALRKDLAR 737
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1202 AVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIEtAASKQLQELALQSEQVLEGAQKTLLLANEKVEEft 1281
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-AEIEELEAQIEQLKEELKALREALDELRAELTL-- 814
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034670445 1282 tfVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1357
Cdd:TIGR02168  815 --LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1009-1360 1.43e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1009 VKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAeensqvtfpriQVTSLSPSR 1088
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-----------GYELLKEKE 233
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1089 SMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRM--ERDITMKRHlIEDLKFRQKvNLESNKS 1166
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK-IGELEAEIA-SLERSIA 311
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1167 FSEM-LQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEkkdlkltLLVSRISETESAMAEIE 1245
Cdd:TIGR02169  312 EKEReLEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE-------DLRAELEEVDKEFAETR 384
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1246 TAASKQLQEL-ALQSE-QVLEGAQKTLLLANEKVEEfttfvkALAkELQNDVHVVRRQIRELK-KMKKNRDACKTSTHKA 1322
Cdd:TIGR02169  385 DELKDYREKLeKLKREiNELKRELDRLQEELQRLSE------ELA-DLNAAIAGIEAKINELEeEKEDKALEIKKQEWKL 457
                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 1034670445 1323 QTLAAsILNISRSDLEEILDTEDQVEIEKTKIDAENDK 1360
Cdd:TIGR02169  458 EQLAA-DLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
530-813 1.49e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  530 KLRKAERKIENLEKALQLKSQENDELRDAHEK-RKERLQMLQtnYRAVKEQLKQWEegsgMTEIRKIKRADPQQLRQEDS 608
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQLERlRREREKAER--YQALLKEKREYE----GYELLKEKEALERQKEAIER 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  609 davwnelayfkrenqelmiQKMNLEEELDELKVHISIDKAAIQELNRcVAERREEQLFRSGEDDEVKRSTPEKNGKEMLE 688
Cdd:TIGR02169  245 -------------------QLASLEEELEKLTEEISELEKRLEEIEQ-LLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  689 QTLQKVTELENRLKSFEKRSRKLKEgnkklmkENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELE 768
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEA-------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD 377
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1034670445  769 TEVTSLRRQVAEA----NALRNENEELINPMEKSHQSADRAKSEMATMK 813
Cdd:TIGR02169  378 KEFAETRDELKDYreklEKLKREINELKRELDRLQEELQRLSEELADLN 426
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
529-663 1.58e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 1.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  529 QKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEgsgmteirKIKRADPQQLR---Q 605
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEA--------RIKKYEEQLGNvrnN 88
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034670445  606 EDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREE 663
Cdd:COG1579     89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE 146
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1047-1382 1.94e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1047 LRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQlqYKLKNATNELTKQSSNVKTLKFELLAKE 1126
Cdd:PRK03918   174 IKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEL--EKLEKEVKELEELKEEIEELEKELESLE 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1127 EHIKEMHEKISRMERDITMKRHLIEDLKFRQKvNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEK 1206
Cdd:PRK03918   252 GSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1207 SQYEQMyqksKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQ------ELALQSEQVLEGAQKTLLLANEKVEEF 1280
Cdd:PRK03918   331 KELEEK----EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElerlkkRLTGLTPEKLEKELEELEKAKEEIEEE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1281 TTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACK---TSTHKAQTLAASILNISR--SDLEEILDTEDQVEIEKTKID 1355
Cdd:PRK03918   407 ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRieKELKEIEEKERKLRKELRELE 486
                          330       340
                   ....*....|....*....|....*..
gi 1034670445 1356 AENDKEWMLYIQKLLEGQSLALSPRLK 1382
Cdd:PRK03918   487 KVLKKESELIKLKELAEQLKELEEKLK 513
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
625-793 2.70e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  625 LMIQKMN------LEEELDELkvhisidkaaIQELnrcvaerREEQLFrsgE-DDEVKRSTPEKNGKemLEQTLQKVTEL 697
Cdd:PRK05771     1 LAPVRMKkvlivtLKSYKDEV----------LEAL-------HELGVV---HiEDLKEELSNERLRK--LRSLLTKLSEA 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  698 ENRLKSFEKRSRKLKEGNKKLmkendflksllkqqqedtetREKELEQIIKGSK----DVEKENTELQVKISELETEVTS 773
Cdd:PRK05771    59 LDKLRSYLPKLNPLREEKKKV--------------------SVKSLEELIKDVEeeleKIEKEIKELEEEISELENEIKE 118
                          170       180
                   ....*....|....*....|
gi 1034670445  774 LRRQVAEANALRNENEELIN 793
Cdd:PRK05771   119 LEQEIERLEPWGNFDLDLSL 138
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1022-1274 2.90e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 2.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1022 QQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSseitslaeensqvtfpriqvtslspsrsmDLEMKQLQYKL 1101
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL-----------------------------ERRIAALARRI 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1102 KNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDI-TMKRHLIEDLKFRQKVNLESNKSFsEMLQNLDKKVKT 1180
Cdd:COG4942     72 RALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVRRL-QYLKYLAPARRE 150
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1181 LTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEK----KDLKLTLLVSRISETESAMAEIETAAsKQLQELA 1256
Cdd:COG4942    151 QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEAlkaeRQKLLARLEKELAELAAELAELQQEA-EELEALI 229
                          250
                   ....*....|....*...
gi 1034670445 1257 LQSEQVLEGAQKTLLLAN 1274
Cdd:COG4942    230 ARLEAEAAAAAERTPAAG 247
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
671-797 3.19e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  671 DDEVKRSTPEKNGKEMLEqtlqkVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIikgs 750
Cdd:COG2433    383 EELIEKELPEEEPEAERE-----KEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA---- 453
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1034670445  751 KDVEKENTELQVKISELETEVTSLRRQVAEanaLRNENEELINPMEK 797
Cdd:COG2433    454 RSEERREIRKDREISRLDREIERLERELEE---ERERIEELKRKLER 497
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
526-816 3.27e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  526 EELQKLRK--AERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMT-----EIRKIKRA 598
Cdd:PRK03918   372 EELERLKKrlTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcgrELTEEHRK 451
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  599 DPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAA--IQELNRCVAERREEQLFRSGEDDEVKR 676
Cdd:PRK03918   452 ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqLKELEEKLKKYNLEELEKKAEEYEKLK 531
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  677 STPEKNGKEM--LEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKEndfLKSLLKQQQEDTETREKELEQIIK---GSK 751
Cdd:PRK03918   532 EKLIKLKGEIksLKKELEKLEELKKKLAELEKKLDELEEELAELLKE---LEELGFESVEELEERLKELEPFYNeylELK 608
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034670445  752 DVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRS 816
Cdd:PRK03918   609 DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSR 673
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
1093-1269 3.61e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1093 EMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVN---------LES 1163
Cdd:COG3883     31 ELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSggsvsyldvLLG 110
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1164 NKSFSEMLQNLD------KKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISET 1237
Cdd:COG3883    111 SESFSDFLDRLSalskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAE 190
                          170       180       190
                   ....*....|....*....|....*....|..
gi 1034670445 1238 ESAMAEIETAASKQLQELALQSEQVLEGAQKT 1269
Cdd:COG3883    191 EAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
mukB PRK04863
chromosome partition protein MukB;
533-813 3.71e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  533 KAERKIENLEKA-LQLKSQ-----ENDELRDAHEKRKERLQmlqTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQE 606
Cdd:PRK04863   349 KIERYQADLEELeERLEEQnevveEADEQQEENEARAEAAE---EEVDELKSQLADYQQALDVQQTRAIQYQQAVQALER 425
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  607 DSDavWNELAYFKRENQELMI-----QKMNLEEELDELKVHISIDKAAiqelnrcvAERREE--QLFRSGEDdEVKRSTP 679
Cdd:PRK04863   426 AKQ--LCGLPDLTADNAEDWLeefqaKEQEATEELLSLEQKLSVAQAA--------HSQFEQayQLVRKIAG-EVSRSEA 494
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  680 EKNGKEMLEQ------TLQKVTELENRLKSFEKRSRK-------LKEGNKKLMKE---NDFLKSLLKQQQEDTETREKEL 743
Cdd:PRK04863   495 WDVARELLRRlreqrhLAEQLQQLRMRLSELEQRLRQqqraerlLAEFCKRLGKNlddEDELEQLQEELEARLESLSESV 574
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  744 EQIIKGSKDVEKENTELQVKISELETE----------VTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMK 813
Cdd:PRK04863   575 SEARERRMALRQQLEQLQARIQRLAARapawlaaqdaLARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARK 654
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1092-1361 5.40e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 5.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1092 LEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKfrqkvnlesnksfsEML 1171
Cdd:COG1196    225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ--------------AEE 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1172 QNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQ 1251
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445 1252 LQELALQSEQVLEGAQKTLLLANEKVEEfttfvkalAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILN 1331
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAEL--------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442
                          250       260       270
                   ....*....|....*....|....*....|
gi 1034670445 1332 ISRSDLEEILDTEDQVEIEKTKIDAENDKE 1361
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEA 472
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
605-810 5.92e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 5.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  605 QEDSDAVWNELAYFKRENQELMIQKmnLEEELDELKVHISIDKAAIQELNrcvAERREEQLFRSGEDDEVKRStpekngK 684
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEE--LEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEA------Q 287
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  685 EMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKI 764
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1034670445  765 SELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMA 810
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
145-663 6.28e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.18  E-value: 6.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  145 SLVVEREKQKSEAKDRKVLEILQVKDAKIQEFEQRESvLKQEINDLVKRKIAVDEENAFLRKE--FSDLEKK-FKDKSQE 221
Cdd:PRK02224   240 DEVLEEHEERREELETLEAEIEDLRETIAETEREREE-LAEEVRDLRERLEELEEERDDLLAEagLDDADAEaVEARREE 318
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  222 IKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQS 301
Cdd:PRK02224   319 LEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  302 KYNALSLQLSNKQTELiqkdmdiTLVRKELQELQNlykqnsthtaQQAELIQQLQVLNMDTQKVLRNQEDVHTAESisYQ 381
Cdd:PRK02224   399 RFGDAPVDLGNAEDFL-------EELREERDELRE----------REAELEATLRTARERVEEAEALLEAGKCPEC--GQ 459
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  382 KLYNELHICFETTKsneamlRQSVTNLQDQLLQKEQENAKLKEKLQEsqgaplplpqesdpdysaqvphrpslssLETLm 461
Cdd:PRK02224   460 PVEGSPHVETIEED------RERVEELEAELEDLEEEVEEVEERLER----------------------------AEDL- 504
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  462 VSQKSEIEYLQEKLKIANEKLSENIS---------ANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEelQKLR 532
Cdd:PRK02224   505 VEAEDRIERLEERREDLEELIAERREtieekreraEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELN--SKLA 582
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  533 KAERKIENLEKALQLKSqENDELRDAHEKRKERLQMLQTNYRAVKEQLKQweegsgmteirkiKRADPQQLRQE-DSDAV 611
Cdd:PRK02224   583 ELKERIESLERIRTLLA-AIADAEDEIERLREKREALAELNDERRERLAE-------------KRERKRELEAEfDEARI 648
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034670445  612 wnELAYFKRENQELMIQKMN-----LEEELDELKVHISIDKAAIQELNRcVAERREE 663
Cdd:PRK02224   649 --EEAREDKERAEEYLEQVEekldeLREERDDLQAEIGAVENELEELEE-LRERREA 702
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
153-358 6.43e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 40.65  E-value: 6.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  153 QKSEAKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLvkrkiavDEENAFLRKEFSDLEKKFK---DKSQEIKDTKECV 229
Cdd:pfam07888   48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAEL-------KEELRQSREKHEELEEKYKelsASSEELSEEKDAL 120
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  230 QNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLR---KQEAHLRKEKYSTDAKIKTfednliearkEVEVSQSKYNAL 306
Cdd:pfam07888  121 LAQRAAHEARIRELEEDIKTLTQRVLERETELERMKeraKKAGAQRKEEEAERKQLQA----------KLQQTEEELRSL 190
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1034670445  307 SLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVL 358
Cdd:pfam07888  191 SKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSL 242
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
205-792 6.96e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.11  E-value: 6.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  205 RKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLR----KQEAHLRKEKYSTDA 280
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTqkreAQEEQLKKQQLLKQL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  281 KIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ----ELQNLYKQNSTHTAQQAELIQQLQ 356
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQskmrSRAKLLMKRAAHVKQQSSIEEQRR 345
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  357 VLNMDTQKVLRNQEdvhtaesisyqklYNELHICFETTKSNEAMLRQSVTNLQDQ---LLQKEQENAKLKEKLQESQGAP 433
Cdd:TIGR00618  346 LLQTLHSQEIHIRD-------------AHEVATSIREISCQQHTLTQHIHTLQQQkttLTQKLQSLCKELDILQREQATI 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  434 LPLPQESDPD----YSAQVPHRPSLSSLETLMV-------SQKSEIEYLQE-----KLKIANEKLSENISANKGFSRKSI 497
Cdd:TIGR00618  413 DTRTSAFRDLqgqlAHAKKQQELQQRYAELCAAaitctaqCEKLEKIHLQEsaqslKEREQQLQTKEQIHLQETRKKAVV 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  498 MTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQ----KLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNY 573
Cdd:TIGR00618  493 LARLLELQEEPCPLCGSCIHPNPARQDIDNPGpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSF 572
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  574 RAVKEQLKQWEEGSGMT--EIRKIKRADPQQLRQEDSDAVWNELAYFKRE----NQELMIQKMNLEEELDELKVH----- 642
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLqnITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdLQDVRLHLQQCSQELALKLTAlhalq 652
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  643 --ISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKS----FEKRSRKLKEGNK 716
Cdd:TIGR00618  653 ltLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEydreFNEIENASSSLGS 732
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034670445  717 KLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELI 792
Cdd:TIGR00618  733 DLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEI 808
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
490-640 6.97e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.00  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  490 KGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKalqlksqENDELRDAHEKRKERLQML 569
Cdd:COG2433    374 RGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEA-------EVEELEAELEEKDERIERL 446
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034670445  570 QTNYRAVKEqlkqwEEGSGMTEIRKIKRadpqqlRQEDSDAVWNELAYFKRENQElmiqkmnLEEELDELK 640
Cdd:COG2433    447 ERELSEARS-----EERREIRKDREISR------LDREIERLERELEEERERIEE-------LKRKLERLK 499
PTZ00121 PTZ00121
MAEBL; Provisional
149-642 9.55e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 9.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  149 EREKQKSEAKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKK---------FKDKS 219
Cdd:PTZ00121  1374 EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKaeeakkadeAKKKA 1453
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  220 QEIKDTKECVQNKEEQNRL-VIKNLEEENKKlstrCTDLLNDLEKLRKQEAHLRKEKystDAKIKTFEDNLIEARKEVEV 298
Cdd:PTZ00121  1454 EEAKKAEEAKKKAEEAKKAdEAKKKAEEAKK----ADEAKKKAEEAKKKADEAKKAA---EAKKKADEAKKAEEAKKADE 1526
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  299 SQSKYNALSLQLSNKQTELIQKDmditlvrkELQELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESI 378
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKAD--------ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  379 syqKLYNElhicfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESqgaplplpqesdpdysaqvphrpslsslE 458
Cdd:PTZ00121  1599 ---KLYEE-----EKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK----------------------------E 1642
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  459 TLMVSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAER-- 536
Cdd:PTZ00121  1643 AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEElk 1722
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  537 --KIENLEKALQLKSQENDELRDAHEKRKER-----------------LQMLQTNYRAVKEQLKQWEEGSGMTEIRKIK- 596
Cdd:PTZ00121  1723 kaEEENKIKAEEAKKEAEEDKKKAEEAKKDEeekkkiahlkkeeekkaEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKd 1802
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034670445  597 ----RADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVH 642
Cdd:PTZ00121  1803 ifdnFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKH 1852
COG5022 COG5022
Myosin heavy chain [General function prediction only];
451-769 9.95e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 40.45  E-value: 9.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  451 RPSLSSLET--LMVSQKSEIEYLQEKLKIaneKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSsfTDSEEL 528
Cdd:COG5022    800 QPLLSLLGSrkEYRSYLACIIKLQKTIKR---EKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKET--IYLQSA 874
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  529 QKLRKAERKIENL----EKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEgsgmtEIRKIkRADPQQLR 604
Cdd:COG5022    875 QRVELAERQLQELkidvKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKK-----LLNNI-DLEEGPSI 948
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  605 QEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGK 684
Cdd:COG5022    949 EYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAEL 1028
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034670445  685 EMLEQTLQKVTELENRLKSFEKRSRKLKEGNK---------KLMKENDFLKSLLKQQQEDTETREKELEqiikgSKDVEK 755
Cdd:COG5022   1029 QSASKIISSESTELSILKPLQKLKGLLLLENNqlqarykalKLRRENSLLDDKQLYQLESTENLLKTIN-----VKDLEV 1103
                          330
                   ....*....|....
gi 1034670445  756 ENTELQVKISELET 769
Cdd:COG5022   1104 TNRNLVKPANVLQF 1117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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