|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
193-334 |
9.57e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 74.97 E-value: 9.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 193 DLENIPPLPQMT--TYLYARFNHISHIQAgDFKGLTKLRRIDLSGNSISSIhNDALRLLPALQDLILPENQLAALPV--- 267
Cdd:COG4886 102 DLSGNEELSNLTnlESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEelg 179
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 268 -LPSgIEFLDVRLNRLQSsgiQPEAFVALKKLQFLYLANNMLDSIPGPLPL--SLRSLHLQNNMIETMES 334
Cdd:COG4886 180 nLTN-LKELDLSNNQITD---LPEPLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDLPE 245
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
188-360 |
1.03e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 60.96 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 188 YCDDADLENIPPLPQMT--TYLYARFNHISHIQagDFKGLTKLRRIDLSGNSISSIHNdaLRLLPALQDLILpENQlaal 265
Cdd:cd21340 30 YLYDNKITKIENLEFLTnlTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRISVVEG--LENLTNLEELHI-ENQ---- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 266 pVLPSGIEFLdvrlnrlqssgIQPEAFVALKK-LQFLYLANNMLDSIPGPLPL-SLRSLHLQNNMIETMEsdtfcDTGEH 343
Cdd:cd21340 101 -RLPPGEKLT-----------FDPRSLAALSNsLRVLNISGNNIDSLEPLAPLrNLEQLDASNNQISDLE-----ELLDL 163
|
170
....*....|....*..
gi 1720355541 344 RHERRQLEDIRLDGNPI 360
Cdd:cd21340 164 LSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
205-262 |
3.34e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.22 E-value: 3.34e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720355541 205 TYLYARFNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQL 262
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
190-376 |
2.54e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 58.94 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 190 DDADLENIPP-LPQMTTYLYARFNHISHIQAG--DfkgltKLRRIDLSGNSISSIHNdalRLLPALQDLILPENQLAALP 266
Cdd:PRK15370 207 DNNELKSLPEnLQGNIKTLYANSNQLTSIPATlpD-----TIQEMELSINRITELPE---RLPSALQSLDLFHNKISCLP 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 267 -VLPSGIEFLDVRLNRLQS------SGI-----QPEAFVALKK-----LQFLYLANNMLDSIPGPLPLSLRSLHLQNNMI 329
Cdd:PRK15370 279 eNLPEELRYLSVYDNSIRTlpahlpSGIthlnvQSNSLTALPEtlppgLKTLEAGENALTSLPASLPPELQVLDVSKNQI 358
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1720355541 330 eTMESDTFCDTGEHRHERRQLEdIRLDGN-PINLSLFPEAYFCLPRLP 376
Cdd:PRK15370 359 -TVLPETLPPTITTLDVSRNAL-TNLPENlPAALQIMQASRNNLVRLP 404
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
193-334 |
9.57e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 74.97 E-value: 9.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 193 DLENIPPLPQMT--TYLYARFNHISHIQAgDFKGLTKLRRIDLSGNSISSIhNDALRLLPALQDLILPENQLAALPV--- 267
Cdd:COG4886 102 DLSGNEELSNLTnlESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEelg 179
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 268 -LPSgIEFLDVRLNRLQSsgiQPEAFVALKKLQFLYLANNMLDSIPGPLPL--SLRSLHLQNNMIETMES 334
Cdd:COG4886 180 nLTN-LKELDLSNNQITD---LPEPLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDLPE 245
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
188-360 |
1.03e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 60.96 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 188 YCDDADLENIPPLPQMT--TYLYARFNHISHIQagDFKGLTKLRRIDLSGNSISSIHNdaLRLLPALQDLILpENQlaal 265
Cdd:cd21340 30 YLYDNKITKIENLEFLTnlTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRISVVEG--LENLTNLEELHI-ENQ---- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 266 pVLPSGIEFLdvrlnrlqssgIQPEAFVALKK-LQFLYLANNMLDSIPGPLPL-SLRSLHLQNNMIETMEsdtfcDTGEH 343
Cdd:cd21340 101 -RLPPGEKLT-----------FDPRSLAALSNsLRVLNISGNNIDSLEPLAPLrNLEQLDASNNQISDLE-----ELLDL 163
|
170
....*....|....*..
gi 1720355541 344 RHERRQLEDIRLDGNPI 360
Cdd:cd21340 164 LSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
205-262 |
3.34e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.22 E-value: 3.34e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720355541 205 TYLYARFNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQL 262
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
190-376 |
2.54e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 58.94 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 190 DDADLENIPP-LPQMTTYLYARFNHISHIQAG--DfkgltKLRRIDLSGNSISSIHNdalRLLPALQDLILPENQLAALP 266
Cdd:PRK15370 207 DNNELKSLPEnLQGNIKTLYANSNQLTSIPATlpD-----TIQEMELSINRITELPE---RLPSALQSLDLFHNKISCLP 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 267 -VLPSGIEFLDVRLNRLQS------SGI-----QPEAFVALKK-----LQFLYLANNMLDSIPGPLPLSLRSLHLQNNMI 329
Cdd:PRK15370 279 eNLPEELRYLSVYDNSIRTlpahlpSGIthlnvQSNSLTALPEtlppgLKTLEAGENALTSLPASLPPELQVLDVSKNQI 358
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1720355541 330 eTMESDTFCDTGEHRHERRQLEdIRLDGN-PINLSLFPEAYFCLPRLP 376
Cdd:PRK15370 359 -TVLPETLPPTITTLDVSRNAL-TNLPENlPAALQIMQASRNNLVRLP 404
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
226-308 |
1.75e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 226 TKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLaalpvlpsgiefldvrlnrlqsSGIQPEAFVALKKLQFLYLAN 305
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL----------------------TTLSPGAFSGLPSLRYLDLSG 58
|
...
gi 1720355541 306 NML 308
Cdd:pfam13855 59 NRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
275-329 |
9.95e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 9.95e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1720355541 275 LDVRLNRLQSsgIQPEAFVALKKLQFLYLANNMLDSIPG----PLPlSLRSLHLQNNMI 329
Cdd:pfam13855 6 LDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPgafsGLP-SLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
194-332 |
1.26e-05 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 47.46 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 194 LENIPPLPQMTTYLYARFNHISHIQAGDfKGLTKLRridLSGNSISSIHndalRLLPALQDLILPENQLAALPVLPSGIE 273
Cdd:PRK15387 254 LTSLPVLPPGLLELSIFSNPLTHLPALP-SGLCKLW---IFGNQLTSLP----VLPPGLQELSVSDNQLASLPALPSELC 325
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1720355541 274 FLDVRLNRLQSSGIQPEAfvalkkLQFLYLANNMLDSIPgPLPLSLRSLHLQNNMIETM 332
Cdd:PRK15387 326 KLWAYNNQLTSLPTLPSG------LQELSVSDNQLASLP-TLPSELYKLWAYNNRLTSL 377
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
186-331 |
2.94e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 45.69 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 186 SVYCDDADLENIPPLPQMT--TYLYARFNHISHIqaGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLA 263
Cdd:COG4886 232 TLDLSNNQLTDLPELGNLTnlEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLN 309
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720355541 264 ALPVLPSGIEFLDVRLNRLQSSGIQPEAFVALKKLQFLYLANNMLDSIPGPLPLSLRSLHLQNNMIET 331
Cdd:COG4886 310 LLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEA 377
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
191-335 |
3.72e-05 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 45.92 E-value: 3.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 191 DADLENIPPLPQMTTYLYARFNHISHIQAGDfkglTKLRRIDLSGNSISSI------------HNDALRLLPAL----QD 254
Cdd:PRK15387 311 DNQLASLPALPSELCKLWAYNNQLTSLPTLP----SGLQELSVSDNQLASLptlpselyklwaYNNRLTSLPALpsglKE 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 255 LILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVALKklqflyLANNMLDSIPGPLplslrsLHLQNNMIETMES 334
Cdd:PRK15387 387 LIVSGNRLTSLPVLPSELKELMVSGNRLTSLPMLPSGLLSLS------VYRNQLTRLPESL------IHLSSETTVNLEG 454
|
.
gi 1720355541 335 D 335
Cdd:PRK15387 455 N 455
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
225-332 |
3.83e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 42.46 E-value: 3.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 225 LTKLRRIDLSGNSISSIHNDALRLLP-----ALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVAL---- 295
Cdd:PRK15387 192 VQKMRACLNNGNAVLNVGESGLTTLPdclpaHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSLPVLPPGLLELsifs 271
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1720355541 296 ----------KKLQFLYLANNMLDSIPgPLPLSLRSLHLQNNMIETM 332
Cdd:PRK15387 272 nplthlpalpSGLCKLWIFGNQLTSLP-VLPPGLQELSVSDNQLASL 317
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
222-360 |
2.07e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 39.65 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 222 FKGLTKLRRIDLSGNSIsSIHN----DALRLLPALQDLILPENQLA---------ALPVLPSGIEFLDVRLNRLQSSGIQ 288
Cdd:cd00116 77 LTKGCGLQELDLSDNAL-GPDGcgvlESLLRSSSLQELKLNNNGLGdrglrllakGLKDLPPALEKLVLGRNRLEGASCE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355541 289 P--EAFVALKKLQFLYLANNML--DSIP-----GPLPLSLRSLHLQNNMIETMESDTFCDTGEHrheRRQLEDIRLDGNP 359
Cdd:cd00116 156 AlaKALRANRDLKELNLANNGIgdAGIRalaegLKANCNLEVLDLNNNGLTDEGASALAETLAS---LKSLEVLNLGDNN 232
|
.
gi 1720355541 360 I 360
Cdd:cd00116 233 L 233
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
296-333 |
5.94e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 37.84 E-value: 5.94e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1720355541 296 KKLQFLYLANNMLDSIPGPLPLS-LRSLHLQNNMIETME 333
Cdd:cd21340 24 KNLKVLYLYDNKITKIENLEFLTnLTHLYLQNNQIEKIE 62
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
296-327 |
6.69e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.14 E-value: 6.69e-03
10 20 30
....*....|....*....|....*....|...
gi 1720355541 296 KKLQFLYLANNMLDSIPGPLPL-SLRSLHLQNN 327
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLpNLETLDLSGN 33
|
|
|