|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
73-399 |
5.88e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 5.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 73 REQLLKYQnEYNAvKEREFHNQYRLNSLKEEKIIIVKEFEKITkpgEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 152
Cdd:COG1196 209 AEKAERYR-ELKE-ELKELEAELLLLKLRELEAELEELEAELE---ELEAELEELEAELAELEAELEELRLELEELELEL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 153 ASKQKQLLKEQKELEELLGHQVVLKDEVAhhqtipvQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENkvsai 232
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRR-------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEE----- 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 233 vdEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRN 312
Cdd:COG1196 352 --ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 313 LRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKD 392
Cdd:COG1196 430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
|
....*..
gi 2217367999 393 FLKAQQK 399
Cdd:COG1196 510 VKAALLL 516
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
132-409 |
8.01e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 8.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 132 EELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL 211
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 212 EQEVKTLNDSLKKVENKvsaivdeKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEAtsltergildlNLRNSLID 291
Cdd:TIGR02168 315 ERQLEELEAQLEELESK-------LDELAEELAELEEKLEELKEELESLEAELEELEAELE-----------ELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 292 KQNYHDELSRKQREKERDFRNLRKMELLLKVSWDAL--RQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMK 369
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLedRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL 456
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2217367999 370 ELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKA 409
Cdd:TIGR02168 457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
71-810 |
2.94e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.13 E-value: 2.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 71 KMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKitKPGEMEKKMKILRESTEELRKEIMQKKLEiknlRE 150
Cdd:pfam02463 213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES--SKQEIEKEEEKLAQVLKENKEEEKEKKLQ----EE 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 151 DLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL-----------EQEVKTLN 219
Cdd:pfam02463 287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELeikreaeeeeeEELEKLQE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 220 DSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNL---RNSLIDKQNYH 296
Cdd:pfam02463 367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILeeeEESIELKQGKL 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 297 DELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQenMKELVVNLL 376
Cdd:pfam02463 447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLAL--IKDGVGGRI 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 377 RMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKK-----------KKCEIYRRLREFAKLYDTIRNERNKF 445
Cdd:pfam02463 525 ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVraltelplgarKLRLLIPKLKLPLKSIAVLEIDPILN 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 446 VNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNN 525
Cdd:pfam02463 605 LAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEK 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 526 IDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAE 605
Cdd:pfam02463 685 AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEE 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 606 KQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKpdgENRARFLPGKDLTEKEMIQKLDKLELQLAKKE 685
Cdd:pfam02463 765 EKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE---LKEEAELLEEEQLLIEQEEKIKEEELEELALE 841
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 686 EKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREKEDFI 765
Cdd:pfam02463 842 LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE 921
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 2217367999 766 FTCNSRIE--KGLPLNKEIEKEWLKVLRDEEMHALAIAEKSQEFLEA 810
Cdd:pfam02463 922 RIKEEAEIllKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLA 968
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
119-650 |
3.17e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.27 E-value: 3.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 119 EMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKit 198
Cdd:pfam15921 346 ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDD-- 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 199 rKKVEMEKkkivLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKllELARENEATSLTER 278
Cdd:pfam15921 424 -RNMEVQR----LEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE--ELTAKKMTLESSER 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 279 GILDLNlrNSLIDKQNyHDELSRKQREKERDFRNLRKMELL-LKVSWDALRQTQAlhqrlllekiisemESKLVEQQLAE 357
Cdd:pfam15921 497 TVSDLT--ASLQEKER-AIEATNAEITKLRSRVDLKLQELQhLKNEGDHLRNVQT--------------ECEALKLQMAE 559
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 358 ENK---LLKEQ-ENMKELVVNLLRMTQIKIDEKEQkskdflkaqqkytnIVKEMKAKDLEIRIHKKKKCEIYRRLREFAK 433
Cdd:pfam15921 560 KDKvieILRQQiENMTQLVGQHGRTAGAMQVEKAQ--------------LEKEINDRRLELQEFKILKDKKDAKIRELEA 625
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 434 LYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRN--SAVSQERKLQNSMLKHANnvtirESMQNDVRKIVSK 511
Cdd:pfam15921 626 RVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNelNSLSEDYEVLKRNFRNKS-----EEMETTTNKLKMQ 700
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 512 LQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKryekavqhrnesgvQLIEREEEICIFYEKINIQEKMKLNGEIEIHL 591
Cdd:pfam15921 701 LKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK--------------QITAKRGQIDALQSKIQFLEEAMTNANKEKHF 766
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 592 LEEKIQFLKMKIA----EKQRQICVTQKLLPAKRSLDADLAVLQI-------QFSQCTDRIKDLEKQFVK 650
Cdd:pfam15921 767 LKEEKNKLSQELStvatEKNKMAGELEVLRSQERRLKEKVANMEValdkaslQFAECQDIIQRQEQESVR 836
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
73-761 |
2.12e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.51 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 73 REQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFekitkpGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 152
Cdd:TIGR02168 238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEV------SELEEEIEELQKELYALANEISRLEQQKQILRERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 153 ASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAI 232
Cdd:TIGR02168 312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 233 VDEKENVIKEVEGKRALLEIKEREHNQLV--------KLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQR 304
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQqeieellkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 305 EKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLL--RMTQIK 382
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALggRLQAVV 551
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 383 IDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKV------ 456
Cdd:TIGR02168 552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddl 631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 457 -NEIKERHKMSLNEL------EILRNSAVS--QERKLQNSMLKH----ANNVTIRESMQNDVRKIVSKLQEMKEKKEAQL 523
Cdd:TIGR02168 632 dNALELAKKLRPGYRivtldgDLVRPGGVItgGSAKTNSSILERrreiEELEEKIEELEEKIAELEKALAELRKELEELE 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 524 NNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKI 603
Cdd:TIGR02168 712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 604 AEKQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEK--EMIQKLDKLELQL 681
Cdd:TIGR02168 792 EQLKEEL---KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDieSLAAEIEELEELI 868
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 682 AKKEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREK 761
Cdd:TIGR02168 869 EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
63-485 |
8.84e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 8.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 63 EAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKK 142
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 143 LEIKNLREDLASKQKQLLK---EQKELEELLGHQVVLKDEVAHHQTipvqIGKEIEKITRKKVEMEK-KKIVLEQEVKTL 218
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEE----RHELYEEAKAKKEELERlKKRLTGLTPEKL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 219 NDSLKKVENKVSAIVDEkenvIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTErgiLDLNLRNSLIDKqnYHDE 298
Cdd:PRK03918 390 EKELEELEKAKEEIEEE----ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRE---LTEEHRKELLEE--YTAE 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 299 LSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLlrM 378
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL--K 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 379 TQIKIDEKEQKSKDFLKaqqkytnivKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNE 458
Cdd:PRK03918 539 GEIKSLKKELEKLEELK---------KKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKD 609
|
410 420
....*....|....*....|....*..
gi 2217367999 459 IKERHKMSLNELEILRNSAVSQERKLQ 485
Cdd:PRK03918 610 AEKELEREEKELKKLEEELDKAFEELA 636
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
113-692 |
1.11e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 113 KITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAhhqtipvqigK 192
Cdd:PTZ00121 1155 EIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA----------K 1224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 193 EIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKeVEGKRALLEIKEREH----NQLVKLLELAR 268
Cdd:PTZ00121 1225 KAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK-AEEARKADELKKAEEkkkaDEAKKAEEKKK 1303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 269 ENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLE--KIISEM 346
Cdd:PTZ00121 1304 ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEakKKADAA 1383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 347 ESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYR 426
Cdd:PTZ00121 1384 KKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK 1463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 427 RLREFAKLYDTIRNERNKfvnllhkaHQKVNEIKERHKMSLNELEILRNSAvsQERKLQNSMLKHANNVTIRESMQNDVR 506
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEE--------AKKADEAKKKAEEAKKKADEAKKAA--EAKKKADEAKKAEEAKKADEAKKAEEA 1533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 507 KIVSKLQEMKEKKEAqlnniDRLANTITMIEEEMVQLRKRYEKAVQHRNesgvqLIEREEEICIFYEKINIQEKMKLNGE 586
Cdd:PTZ00121 1534 KKADEAKKAEEKKKA-----DELKKAEELKKAEEKKKAEEAKKAEEDKN-----MALRKAEEAKKAEEARIEEVMKLYEE 1603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 587 ieihllEEKIQFLKMKIAEKQRqicvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLT 666
Cdd:PTZ00121 1604 ------EKKMKAEEAKKAEEAK-----IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672
|
570 580
....*....|....*....|....*.
gi 2217367999 667 EKEMIQKLDKLELQLAKKEEKLLEKD 692
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEKKAAEALKKEA 1698
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
420-691 |
2.30e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 420 KKCEIYRRLREFAKLYDtirneRNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRE 499
Cdd:COG1196 210 EKAERYRELKEELKELE-----AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 500 SMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQE 579
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 580 KMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRArf 659
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE-- 442
|
250 260 270
....*....|....*....|....*....|..
gi 2217367999 660 lpgKDLTEKEMIQKLDKLELQLAKKEEKLLEK 691
Cdd:COG1196 443 ---ALEEAAEEEAELEEEEEALLELLAELLEE 471
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
73-399 |
5.88e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 5.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 73 REQLLKYQnEYNAvKEREFHNQYRLNSLKEEKIIIVKEFEKITkpgEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 152
Cdd:COG1196 209 AEKAERYR-ELKE-ELKELEAELLLLKLRELEAELEELEAELE---ELEAELEELEAELAELEAELEELRLELEELELEL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 153 ASKQKQLLKEQKELEELLGHQVVLKDEVAhhqtipvQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENkvsai 232
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRR-------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEE----- 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 233 vdEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRN 312
Cdd:COG1196 352 --ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 313 LRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKD 392
Cdd:COG1196 430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
|
....*..
gi 2217367999 393 FLKAQQK 399
Cdd:COG1196 510 VKAALLL 516
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
132-409 |
8.01e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 8.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 132 EELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL 211
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 212 EQEVKTLNDSLKKVENKvsaivdeKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEAtsltergildlNLRNSLID 291
Cdd:TIGR02168 315 ERQLEELEAQLEELESK-------LDELAEELAELEEKLEELKEELESLEAELEELEAELE-----------ELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 292 KQNYHDELSRKQREKERDFRNLRKMELLLKVSWDAL--RQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMK 369
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLedRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL 456
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2217367999 370 ELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKA 409
Cdd:TIGR02168 457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
71-810 |
2.94e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.13 E-value: 2.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 71 KMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKitKPGEMEKKMKILRESTEELRKEIMQKKLEiknlRE 150
Cdd:pfam02463 213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES--SKQEIEKEEEKLAQVLKENKEEEKEKKLQ----EE 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 151 DLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL-----------EQEVKTLN 219
Cdd:pfam02463 287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELeikreaeeeeeEELEKLQE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 220 DSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNL---RNSLIDKQNYH 296
Cdd:pfam02463 367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILeeeEESIELKQGKL 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 297 DELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQenMKELVVNLL 376
Cdd:pfam02463 447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLAL--IKDGVGGRI 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 377 RMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKK-----------KKCEIYRRLREFAKLYDTIRNERNKF 445
Cdd:pfam02463 525 ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVraltelplgarKLRLLIPKLKLPLKSIAVLEIDPILN 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 446 VNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNN 525
Cdd:pfam02463 605 LAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEK 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 526 IDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAE 605
Cdd:pfam02463 685 AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEE 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 606 KQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKpdgENRARFLPGKDLTEKEMIQKLDKLELQLAKKE 685
Cdd:pfam02463 765 EKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE---LKEEAELLEEEQLLIEQEEKIKEEELEELALE 841
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 686 EKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREKEDFI 765
Cdd:pfam02463 842 LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE 921
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 2217367999 766 FTCNSRIE--KGLPLNKEIEKEWLKVLRDEEMHALAIAEKSQEFLEA 810
Cdd:pfam02463 922 RIKEEAEIllKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLA 968
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
119-650 |
3.17e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.27 E-value: 3.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 119 EMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKit 198
Cdd:pfam15921 346 ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDD-- 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 199 rKKVEMEKkkivLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKllELARENEATSLTER 278
Cdd:pfam15921 424 -RNMEVQR----LEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE--ELTAKKMTLESSER 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 279 GILDLNlrNSLIDKQNyHDELSRKQREKERDFRNLRKMELL-LKVSWDALRQTQAlhqrlllekiisemESKLVEQQLAE 357
Cdd:pfam15921 497 TVSDLT--ASLQEKER-AIEATNAEITKLRSRVDLKLQELQhLKNEGDHLRNVQT--------------ECEALKLQMAE 559
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 358 ENK---LLKEQ-ENMKELVVNLLRMTQIKIDEKEQkskdflkaqqkytnIVKEMKAKDLEIRIHKKKKCEIYRRLREFAK 433
Cdd:pfam15921 560 KDKvieILRQQiENMTQLVGQHGRTAGAMQVEKAQ--------------LEKEINDRRLELQEFKILKDKKDAKIRELEA 625
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 434 LYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRN--SAVSQERKLQNSMLKHANnvtirESMQNDVRKIVSK 511
Cdd:pfam15921 626 RVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNelNSLSEDYEVLKRNFRNKS-----EEMETTTNKLKMQ 700
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 512 LQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKryekavqhrnesgvQLIEREEEICIFYEKINIQEKMKLNGEIEIHL 591
Cdd:pfam15921 701 LKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK--------------QITAKRGQIDALQSKIQFLEEAMTNANKEKHF 766
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 592 LEEKIQFLKMKIA----EKQRQICVTQKLLPAKRSLDADLAVLQI-------QFSQCTDRIKDLEKQFVK 650
Cdd:pfam15921 767 LKEEKNKLSQELStvatEKNKMAGELEVLRSQERRLKEKVANMEValdkaslQFAECQDIIQRQEQESVR 836
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
138-461 |
1.52e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 1.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 138 IMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVahhqtipVQIGKEIEKITRKKVEMEKKKIVLEQEVKT 217
Cdd:TIGR02168 672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-------EQLRKELEELSRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 218 LNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLElARENEATSLTERgildlnlrnsLIDKQNYHD 297
Cdd:TIGR02168 745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE-QLKEELKALREA----------LDELRAELT 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 298 ELSRKQREKERDFRNLRKMELLLKVSWDALRQT--QALHQRLLLEKIISEMESKLVEQQlAEENKLLKEQENMKELVVNL 375
Cdd:TIGR02168 814 LLNEEAANLRERLESLERRIAATERRLEDLEEQieELSEDIESLAAEIEELEELIEELE-SELEALLNERASLEEALALL 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 376 LRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKL-YDTIRNERNKFVNLLHKAHQ 454
Cdd:TIGR02168 893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARR 972
|
....*..
gi 2217367999 455 KVNEIKE 461
Cdd:TIGR02168 973 RLKRLEN 979
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
73-761 |
2.12e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.51 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 73 REQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFekitkpGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 152
Cdd:TIGR02168 238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEV------SELEEEIEELQKELYALANEISRLEQQKQILRERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 153 ASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAI 232
Cdd:TIGR02168 312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 233 VDEKENVIKEVEGKRALLEIKEREHNQLV--------KLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQR 304
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQqeieellkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 305 EKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLL--RMTQIK 382
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALggRLQAVV 551
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 383 IDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKV------ 456
Cdd:TIGR02168 552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddl 631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 457 -NEIKERHKMSLNEL------EILRNSAVS--QERKLQNSMLKH----ANNVTIRESMQNDVRKIVSKLQEMKEKKEAQL 523
Cdd:TIGR02168 632 dNALELAKKLRPGYRivtldgDLVRPGGVItgGSAKTNSSILERrreiEELEEKIEELEEKIAELEKALAELRKELEELE 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 524 NNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKI 603
Cdd:TIGR02168 712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 604 AEKQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEK--EMIQKLDKLELQL 681
Cdd:TIGR02168 792 EQLKEEL---KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDieSLAAEIEELEELI 868
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 682 AKKEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREK 761
Cdd:TIGR02168 869 EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
68-691 |
3.59e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 68 EVSKMREQLLKYQNEYNAVKERefhnqyrLNSLKEEKIIIVKEFEKI-TKPGEMEKKMKILRESTEELRKEIMQKKLEIK 146
Cdd:TIGR02168 275 EVSELEEEIEELQKELYALANE-------ISRLEQQKQILRERLANLeRQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 147 NLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVE 226
Cdd:TIGR02168 348 ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 227 NKVSAivDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATsltergildlnLRNSLIDKQNYHDELSRKQREK 306
Cdd:TIGR02168 428 KKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEE-----------AEQALDAAERELAQLQARLDSL 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 307 ERDFRNLRKMELLLKVSWDALRQTQALHQRLLlEKIISEME-SKLVEQQLAE---------ENKLLKEQENMKE------ 370
Cdd:TIGR02168 495 ERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGyEAAIEAALGGrlqavvvenLNAAKKAIAFLKQnelgrv 573
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 371 --LVVNLLRMTQIKIDEKEQKS---------KDFLKAQQKY--------------------TNIVKEMK----------- 408
Cdd:TIGR02168 574 tfLPLDSIKGTEIQGNDREILKniegflgvaKDLVKFDPKLrkalsyllggvlvvddldnaLELAKKLRpgyrivtldgd 653
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 409 --------------------AKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLN 468
Cdd:TIGR02168 654 lvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 469 ELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRY- 547
Cdd:TIGR02168 734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELt 813
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 548 -EKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIhlLEEKIQFLKMKIAEKQRQIcvtQKLLPAKRSLDAD 626
Cdd:TIGR02168 814 lLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES--LAAEIEELEELIEELESEL---EALLNERASLEEA 888
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217367999 627 LAVLQIQFSQCTDRIKDLEKQFVKPDGENRArflpgKDLTEKEMIQKLDKLELQLAKKEEKLLEK 691
Cdd:TIGR02168 889 LALLRSELEELSEELRELESKRSELRRELEE-----LREKLAQLELRLEGLEVRIDNLQERLSEE 948
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
414-714 |
4.75e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 4.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 414 IRIHKKKKCEIYRRLRE----FAKLYDtIRNERNKFVNLLHKAHQKVNEIKE------------------RHKMSLNELE 471
Cdd:TIGR02168 167 ISKYKERRKETERKLERtrenLDRLED-ILNELERQLKSLERQAEKAERYKElkaelrelelallvlrleELREELEELQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 472 ILRNSAVSQ----ERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQE-------MKEKKEAQLNNIDRLANTITMIEEEM 540
Cdd:TIGR02168 246 EELKEAEEEleelTAELQELEEKLEELRLEVSELEEEIEELQKELYAlaneisrLEQQKQILRERLANLERQLEELEAQL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 541 VQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLpak 620
Cdd:TIGR02168 326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI--- 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 621 RSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEKEMIQKLDKLELQLAKKEEKLLEKDFIYEQVSR 700
Cdd:TIGR02168 403 ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482
|
330
....*....|....
gi 2217367999 701 LTDRLCSKTQGCKQ 714
Cdd:TIGR02168 483 ELAQLQARLDSLER 496
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
67-343 |
5.02e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.24 E-value: 5.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 67 TEVSKMREQLLKYQNEYNAVKERefhnqyrlnslkeekiiivkEFEKITKPGEMEKKMKILRESTEELRKEIMQKKLEIK 146
Cdd:COG1196 267 AELEELRLELEELELELEEAQAE--------------------EYELLAELARLEQDIARLEERRRELEERLEELEEELA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 147 NLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVE 226
Cdd:COG1196 327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 227 NKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREK 306
Cdd:COG1196 407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
250 260 270
....*....|....*....|....*....|....*..
gi 2217367999 307 ERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKII 343
Cdd:COG1196 487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
219-567 |
7.56e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 7.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 219 NDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDE 298
Cdd:pfam12128 192 EGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 299 LSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKiiSEMESKLVEQQLAEENKLLKEQENMKELVVNLLRM 378
Cdd:pfam12128 272 TLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAAD--AAVAKDRSELEALEDQHGAFLDADIETAAADQEQL 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 379 TQIKID--EKEQKSKDFLKAQQKYTNivkemKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKV 456
Cdd:pfam12128 350 PSWQSEleNLEERLKALTGKHQDVTA-----KYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 457 NEIKERHKMSLNELEILRNSAVSQERKLQNSmlkhannVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANtitmi 536
Cdd:pfam12128 425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQ-------ATATPELLLQLENFDERIERAREEQEAANAEVERLQS----- 492
|
330 340 350
....*....|....*....|....*....|.
gi 2217367999 537 eeEMVQLRKRYEKAVQHRNESGVQLIEREEE 567
Cdd:pfam12128 493 --ELRQARKRRDQASEALRQASRRLEERQSA 521
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
63-485 |
8.84e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 8.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 63 EAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKK 142
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 143 LEIKNLREDLASKQKQLLK---EQKELEELLGHQVVLKDEVAHHQTipvqIGKEIEKITRKKVEMEK-KKIVLEQEVKTL 218
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEE----RHELYEEAKAKKEELERlKKRLTGLTPEKL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 219 NDSLKKVENKVSAIVDEkenvIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTErgiLDLNLRNSLIDKqnYHDE 298
Cdd:PRK03918 390 EKELEELEKAKEEIEEE----ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRE---LTEEHRKELLEE--YTAE 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 299 LSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLlrM 378
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL--K 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 379 TQIKIDEKEQKSKDFLKaqqkytnivKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNE 458
Cdd:PRK03918 539 GEIKSLKKELEKLEELK---------KKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKD 609
|
410 420
....*....|....*....|....*..
gi 2217367999 459 IKERHKMSLNELEILRNSAVSQERKLQ 485
Cdd:PRK03918 610 AEKELEREEKELKKLEEELDKAFEELA 636
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
129-747 |
1.04e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.26 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 129 ESTEELRKEIMQKKLEI---KNLREDLASKQKQLLKEQKELeeLLGHQVVLKD-----------------EVAHHQTIPV 188
Cdd:pfam15921 138 QSQEDLRNQLQNTVHELeaaKCLKEDMLEDSNTQIEQLRKM--MLSHEGVLQEirsilvdfeeasgkkiyEHDSMSTMHF 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 189 Q-IGKEIEKITRKkvemekkkivLEQEVKTLNDSLKKVENKVSAIVDEKENVIkevegkrallEIKEREHNQLVKLLELA 267
Cdd:pfam15921 216 RsLGSAISKILRE----------LDTEISYLKGRIFPVEDQLEALKSESQNKI----------ELLLQQHQDRIEQLISE 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 268 RENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQrekerdfrnlrkmelllkvswdalrqtQALHQRLL--LEKIISE 345
Cdd:pfam15921 276 HEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ---------------------------NSMYMRQLsdLESTVSQ 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 346 MESKLVEQQLAEENKLlkeQENMKELVVNLLRMTQIKIdEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIY 425
Cdd:pfam15921 329 LRSELREAKRMYEDKI---EELEKQLVLANSELTEART-ERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLW 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 426 RRLREFAKLYDTIRNERNKfvnllhkahqkvneikerHKMSLNELEILRNSAVSQ-----ERKL-----QNSMLKHANNV 495
Cdd:pfam15921 405 DRDTGNSITIDHLRRELDD------------------RNMEVQRLEALLKAMKSEcqgqmERQMaaiqgKNESLEKVSSL 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 496 TIR-ESMQNDVRKIVSKLQemkeKKEAQLNNIDRLANTITMIEEEMvqlrkryEKAVQHRNESGVQLIEREEeicifyek 574
Cdd:pfam15921 467 TAQlESTKEMLRKVVEELT----AKKMTLESSERTVSDLTASLQEK-------ERAIEATNAEITKLRSRVD-------- 527
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 575 INIQEKMKLNGEIEiHL--LEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDAD----LAVLQIQFSQCTDRIKD--LEK 646
Cdd:pfam15921 528 LKLQELQHLKNEGD-HLrnVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtAGAMQVEKAQLEKEINDrrLEL 606
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 647 QFVKPDGENrarflpgKDLTEKEMIQKLDKLELQLAKKEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGY 726
Cdd:pfam15921 607 QEFKILKDK-------KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVL 679
|
650 660
....*....|....*....|.
gi 2217367999 727 QRRIKNATEKMMALVAELSMK 747
Cdd:pfam15921 680 KRNFRNKSEEMETTTNKLKMQ 700
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
75-272 |
1.27e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 75 QLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKItkpgemEKKMKILRESTEELRKEIMQKKLEIKNLREDLA- 153
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNEL------QAELEALQAEIDKLQAEIAEAEAEIEERREELGe 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 154 ---SKQKQ--------LLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSL 222
Cdd:COG3883 91 rarALYRSggsvsyldVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2217367999 223 KKVENKVSaivdEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEA 272
Cdd:COG3883 171 AELEAQQA----EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
73-537 |
5.14e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.89 E-value: 5.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 73 REQLLKYQNEYNAVKEREFHNqyrLNSLKEEKII---IVKEFEK--ITKPGEMEKKMKILRESTEELRK-EIMQKkleIK 146
Cdd:TIGR01612 930 KESIEKFHNKQNILKEILNKN---IDTIKESNLIeksYKDKFDNtlIDKINELDKAFKDASLNDYEAKNnELIKY---FN 1003
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 147 NLREDLASKQKQLLKEQKELEELLGHQVVLKD----------EVAHHQTIpVQIGKEIEKITRKKVEMEKKKIVLEQEVK 216
Cdd:TIGR01612 1004 DLKANLGKNKENMLYHQFDEKEKATNDIEQKIedanknipniEIAIHTSI-YNIIDEIEKEIGKNIELLNKEILEEAEIN 1082
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 217 TLN-----DSLK-------------KVENKVSAIVDEKENVIKEVEGK-RALLEIKEREHNQLVKLLelARENEATSLTE 277
Cdd:TIGR01612 1083 ITNfneikEKLKhynfddfgkeeniKYADEINKIKDDIKNLDQKIDHHiKALEEIKKKSENYIDEIK--AQINDLEDVAD 1160
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 278 RGILDLNLRNSLIDKQNYHDELSRKQREKERdfrnlrkmelllkvswdalrqtqalhqrllLEKIISEMESKLVEQQLAE 357
Cdd:TIGR01612 1161 KAISNDDPEEIEKKIENIVTKIDKKKNIYDE------------------------------IKKLLNEIAEIEKDKTSLE 1210
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 358 ENKLLKEQENMkelvvNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFA----- 432
Cdd:TIGR01612 1211 EVKGINLSYGK-----NLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNishdd 1285
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 433 -KLYDTIRNERNKFVNLLHKAHQKVNEIKERhKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESM--QNDVRKIV 509
Cdd:TIGR01612 1286 dKDHHIISKKHDENISDIREKSLKIIEDFSE-ESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNIlkLNKIKKII 1364
|
490 500
....*....|....*....|....*....
gi 2217367999 510 SKLQEMKEKKEAQLNNI-DRLANTITMIE 537
Cdd:TIGR01612 1365 DEVKEYTKEIEENNKNIkDELDKSEKLIK 1393
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
63-259 |
7.10e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 7.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 63 EAFSTEVSKMREqLLKYQneynavKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQ-- 140
Cdd:pfam17380 368 EEIAMEISRMRE-LERLQ------MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRrl 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 141 ---KKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQ----IGKEIEKITRKKVEMEKKKIVLEQ 213
Cdd:pfam17380 441 eeeRAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQrrkiLEKELEERKQAMIEEERKRKLLEK 520
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2217367999 214 EvktlndslkkVENKVSAIVDEKENVIKEvEGKRALLEIKEREHNQ 259
Cdd:pfam17380 521 E----------MEERQKAIYEEERRREAE-EERRKQQEMEERRRIQ 555
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
63-647 |
8.37e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 8.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 63 EAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKiiivkefekitkpgeMEKKMKILRESTEELRKEIMQKK 142
Cdd:TIGR02168 382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI---------------EELLKKLEEAELKELQAELEELE 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 143 LEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQ---TIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLN 219
Cdd:TIGR02168 447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 220 DSLkKVENKVSA-------------IVDEKENVIKEVE-------GKRALLEIKEREHNQLVKLLELARENE---ATSLT 276
Cdd:TIGR02168 527 ELI-SVDEGYEAaieaalggrlqavVVENLNAAKKAIAflkqnelGRVTFLPLDSIKGTEIQGNDREILKNIegfLGVAK 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 277 ERGILDLNLRNSLIDK-QNYH-----DELSRKQREKERDFRNLRKMELLLKVSW-----DALRQTQALHQRLLLEKI--- 342
Cdd:TIGR02168 606 DLVKFDPKLRKALSYLlGGVLvvddlDNALELAKKLRPGYRIVTLDGDLVRPGGvitggSAKTNSSILERRREIEELeek 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 343 ISEMESKLVEQQlAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQkytnivkemkakdlEIRIHKKKKC 422
Cdd:TIGR02168 686 IEELEEKIAELE-KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA--------------EVEQLEERIA 750
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 423 EIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQ 502
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 503 NDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMK 582
Cdd:TIGR02168 831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 583 LNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAV-----LQIQFSQCTDRIKDLEKQ 647
Cdd:TIGR02168 911 SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEalenkIEDDEEEARRRLKRLENK 980
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
67-371 |
9.40e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 42.81 E-value: 9.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 67 TEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKKLeik 146
Cdd:pfam05557 149 SEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLL--- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 147 nLREDLASKQKQLLKEQKELEELLGHQVV---LKDEVAHHQTIPVQIGKEI---EKITRKKVEMEKKKIVLEQEVKTLND 220
Cdd:pfam05557 226 -LKEEVEDLKRKLEREEKYREEAATLELEkekLEQELQSWVKLAQDTGLNLrspEDLSRRIEQLQQREIVLKEENSSLTS 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 221 SLKKVENKVSAIVDEKENVIKEVEGkralLEIKEREHNQLVKLL-----------------------ELARENEATSLTE 277
Cdd:pfam05557 305 SARQLEKARRELEQELAQYLKKIED----LNKKLKRHKALVRRLqrrvllltkerdgyrailesydkELTMSNYSPQLLE 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 278 RgildLNLRNSLIDKQNYHDELSRKQREK-ERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMESKLveQQLA 356
Cdd:pfam05557 381 R----IEEAEDMTQKMQAHNEEMEAQLSVaEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEVDSLRRKL--ETLE 454
|
330
....*....|....*
gi 2217367999 357 EENKLLKEQENMKEL 371
Cdd:pfam05557 455 LERQRLREQKNELEM 469
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
113-692 |
1.11e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 113 KITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAhhqtipvqigK 192
Cdd:PTZ00121 1155 EIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA----------K 1224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 193 EIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKeVEGKRALLEIKEREH----NQLVKLLELAR 268
Cdd:PTZ00121 1225 KAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK-AEEARKADELKKAEEkkkaDEAKKAEEKKK 1303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 269 ENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLE--KIISEM 346
Cdd:PTZ00121 1304 ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEakKKADAA 1383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 347 ESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYR 426
Cdd:PTZ00121 1384 KKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK 1463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 427 RLREFAKLYDTIRNERNKfvnllhkaHQKVNEIKERHKMSLNELEILRNSAvsQERKLQNSMLKHANNVTIRESMQNDVR 506
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEE--------AKKADEAKKKAEEAKKKADEAKKAA--EAKKKADEAKKAEEAKKADEAKKAEEA 1533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 507 KIVSKLQEMKEKKEAqlnniDRLANTITMIEEEMVQLRKRYEKAVQHRNesgvqLIEREEEICIFYEKINIQEKMKLNGE 586
Cdd:PTZ00121 1534 KKADEAKKAEEKKKA-----DELKKAEELKKAEEKKKAEEAKKAEEDKN-----MALRKAEEAKKAEEARIEEVMKLYEE 1603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 587 ieihllEEKIQFLKMKIAEKQRqicvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLT 666
Cdd:PTZ00121 1604 ------EKKMKAEEAKKAEEAK-----IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672
|
570 580
....*....|....*....|....*.
gi 2217367999 667 EKEMIQKLDKLELQLAKKEEKLLEKD 692
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEKKAAEALKKEA 1698
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
68-265 |
1.43e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.36 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 68 EVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEK--------ITKPGEMEKKMKILRESTEELRKEIM 139
Cdd:TIGR02169 316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAElkeeledlRAELEEVDKEFAETRDELKDYREKLE 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 140 QKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLN 219
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2217367999 220 DSLKKVENKVSaivdEKENVIKEVEGKRALLEIKEREHNQLVKLLE 265
Cdd:TIGR02169 476 EEYDRVEKELS----KLQRELAEAEAQARASEERVRGGRAVEEVLK 517
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12-268 |
1.54e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.35 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 12 RMAALKAKYTLLHDAVMSTQESEVQLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKEREF 91
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 92 HNQYRLNSLKEEKIIIVKEFEKITKP--------GEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQ 163
Cdd:TIGR02168 765 ELEERLEEAEEELAEAEAEIEELEAQieqlkeelKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 164 KELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEV 243
Cdd:TIGR02168 845 EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924
|
250 260
....*....|....*....|....*.
gi 2217367999 244 EG-KRALLEIKEREHNQLVKLLELAR 268
Cdd:TIGR02168 925 AQlELRLEGLEVRIDNLQERLSEEYS 950
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
36-277 |
1.89e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 36 QLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKIt 115
Cdd:TIGR02169 706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL- 784
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 116 KPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAhhqtipvQIGKEIE 195
Cdd:TIGR02169 785 EARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK-------SIEKEIE 857
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 196 KITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKvsaiVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSL 275
Cdd:TIGR02169 858 NLNGKKEELEEELEELEAALRDLESRLGDLKKE----RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
|
..
gi 2217367999 276 TE 277
Cdd:TIGR02169 934 SE 935
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
133-464 |
1.94e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 133 ELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEEllghqvvlkdevahhqtipvqigKEIEKITRKKVEMEKKKIVLE 212
Cdd:COG1196 217 ELKEELKELEAELLLLKLRELEAELEELEAELEELE-----------------------AELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 213 QEVKTLNDSLKKVENKVSAIVDEKEnvikEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDK 292
Cdd:COG1196 274 LELEELELELEEAQAEEYELLAELA----RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 293 QNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKIISEMEsklVEQQLAEenkLLKEQENMKELV 372
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE---LEEAEEA---LLERLERLEEEL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 373 VNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKA 452
Cdd:COG1196 424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
330
....*....|..
gi 2217367999 453 HQKVNEIKERHK 464
Cdd:COG1196 504 EGFLEGVKAALL 515
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
420-691 |
2.30e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 420 KKCEIYRRLREFAKLYDtirneRNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRE 499
Cdd:COG1196 210 EKAERYRELKEELKELE-----AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 500 SMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQE 579
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 580 KMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRArf 659
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE-- 442
|
250 260 270
....*....|....*....|....*....|..
gi 2217367999 660 lpgKDLTEKEMIQKLDKLELQLAKKEEKLLEK 691
Cdd:COG1196 443 ---ALEEAAEEEAELEEEEEALLELLAELLEE 471
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
118-273 |
4.91e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.58 E-value: 4.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 118 GEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLgHQVVLKDEVAHHQTIpVQIGKEIEKI 197
Cdd:PRK00409 512 GEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEE-DKLLEEAEKEAQQAI-KEAKKEADEI 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 198 TRKKVEMEKKKIV------LEQEVKTLNDSLKKVENKVsaiVDEKENVIKEVEGKRalleIKEREHNQLVKLLELARENE 271
Cdd:PRK00409 590 IKELRQLQKGGYAsvkaheLIEARKRLNKANEKKEKKK---KKQKEKQEELKVGDE----VKYLSLGQKGEVLSIPDDKE 662
|
..
gi 2217367999 272 AT 273
Cdd:PRK00409 663 AI 664
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
96-248 |
5.44e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.15 E-value: 5.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 96 RLNSLKEEKIIIVKEfEKITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVV 175
Cdd:PRK12704 50 EAEAIKKEALLEAKE-EIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEK 128
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217367999 176 LKDEVahhQTIPVQIGKEIEKITRKKVEmEKKKIVLEQeVKtlndslKKVENKVSAIVDEKENVIKEVEGKRA 248
Cdd:PRK12704 129 KEEEL---EELIEEQLQELERISGLTAE-EAKEILLEK-VE------EEARHEAAVLIKEIEEEAKEEADKKA 190
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
235-523 |
5.59e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.49 E-value: 5.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 235 EKENVIKEVEGKRALleikerEHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSR-KQREKERDFRNL 313
Cdd:pfam17380 304 EKEEKAREVERRRKL------EEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERiRQEEIAMEISRM 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 314 RKMELLlkvswDALRQTQALHQRLLLE-----KIISEMESKLVEQQLAEENKLLKEQENMKELVVNLL------RMTQIK 382
Cdd:pfam17380 378 RELERL-----QMERQQKNERVRQELEaarkvKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLeeerarEMERVR 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 383 IDEKEQKSKDFLKAQQKytnivKEMKAKDLEIRIHKKKKCEIYRRLR-----EFAKLYDTIRNERNKFVNLLHKAHQKVN 457
Cdd:pfam17380 453 LEEQERQQQVERLRQQE-----EERKRKKLELEKEKRDRKRAEEQRRkilekELEERKQAMIEEERKRKLLEKEMEERQK 527
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217367999 458 EIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDvRKIVSKLQEmKEKKEAQL 523
Cdd:pfam17380 528 AIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERE-REMMRQIVE-SEKARAEY 591
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
11-529 |
6.55e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 40.45 E-value: 6.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 11 TRMAALKAKYTLLHDAVMSTQESEVQLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKM-REQLLKYQneynavKER 89
Cdd:COG5022 875 QRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLlNNIDLEEG------PSI 948
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 90 EFHNQYRLNSLKEEKIIIVKEFEKItkpGEMEKKMKILRestEELRKEImqkkLEIKNLREDLASKQKQLLKEQKELEEL 169
Cdd:COG5022 949 EYVKLPELNKLHEVESKLKETSEEY---EDLLKKSTILV---REGNKAN----SELKNFKKELAELSKQYGALQESTKQL 1018
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 170 lghqVVLKDEVAHHQTIpVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLK--KVENKVSAIVDEKENVIKEVEGKr 247
Cdd:COG5022 1019 ----KELPVEVAELQSA-SKIISSESTELSILKPLQKLKGLLLLENNQLQARYKalKLRRENSLLDDKQLYQLESTENL- 1092
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 248 aLLEIKerehnqlVKLLELARENEATSLTERGILDLNLRNSLIDKQNyHDELSRKQREKERDFRNLRKMELLLkvswDAL 327
Cdd:COG5022 1093 -LKTIN-------VKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEI-SKFLSQLVNTLEPVFQKLSVLQLEL----DGL 1159
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 328 RQTQALHQRLLLEKIISEMESKLVEQQLAEENKLLKEQEnMKELVVNLLRMTQiKIDEKEQKSKDFLKAQQKYTNIVKEM 407
Cdd:COG5022 1160 FWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSE-VNDLKNELIALFS-KIFSGWPRGDKLKKLISEGWVPTEYS 1237
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 408 KAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNS 487
Cdd:COG5022 1238 TSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATEVN 1317
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 2217367999 488 MLKHANNVTIRESMQNDVRKIVSKLQE---MKEKKEAQLNNIDRL 529
Cdd:COG5022 1318 YNSEELDDWCREFEISDVDEELEELIQavkVLQLLKDDLNKLDEL 1362
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
119-278 |
6.84e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.14 E-value: 6.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 119 EMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIpvqigKEIEKIT 198
Cdd:COG1579 21 RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN-----KEYEALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 199 RKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTER 278
Cdd:COG1579 96 KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
108-431 |
7.40e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.05 E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 108 VKEFEKITKPGEMEKKMKILRESteeLRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIP 187
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSS---LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 188 VQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVE-----NKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVK 262
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarlshSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 263 LLELAREneatsltergildlnLRNSLIDKQNYHDElSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEKI 342
Cdd:TIGR02169 827 EKEYLEK---------------EIQELQEQRIDLKE-QIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE 890
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 343 ISEMESKLVEQQLAEENklLKEQENMKELVVNLLRmtqikidEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKC 422
Cdd:TIGR02169 891 RDELEAQLRELERKIEE--LEAQIEKKRKRLSELK-------AKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQ 961
|
....*....
gi 2217367999 423 EIYRRLREF 431
Cdd:TIGR02169 962 RVEEEIRAL 970
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
68-690 |
7.59e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.05 E-value: 7.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 68 EVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEfekitKPGEMEKKMKILRESTEELRKEIMQKKLEIKN 147
Cdd:TIGR02169 252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE-----KIGELEAEIASLERSIAEKERELEDAEERLAK 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 148 LREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVEN 227
Cdd:TIGR02169 327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 228 KVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELAREN--EATSLTERGILDL-NLRNSLIDKQNYHDELSRKQR 304
Cdd:TIGR02169 407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEikKQEWKLEQLAADLsKYEQELYDLKEEYDRVEKELS 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 305 EKERDfrnLRKMELLLKVSWDALRQTQAlhQRLLLEK-------IISEMESKLVEQQLAEE-------NKLLKEQENMKE 370
Cdd:TIGR02169 487 KLQRE---LAEAEAQARASEERVRGGRA--VEEVLKAsiqgvhgTVAQLGSVGERYATAIEvaagnrlNNVVVEDDAVAK 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 371 LVVNLL------RMTQIKIDEKEQKSK---------------DFLKAQQKYTNIVKEM-----------KAKDLEIRIH- 417
Cdd:TIGR02169 562 EAIELLkrrkagRATFLPLNKMRDERRdlsilsedgvigfavDLVEFDPKYEPAFKYVfgdtlvvedieAARRLMGKYRm 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 418 -------------------------------KKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMS 466
Cdd:TIGR02169 642 vtlegelfeksgamtggsraprggilfsrsePAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEI 721
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 467 LNELEILRNSAVSQERKLQNSMlkhannvtiresmqndvrkivSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKR 546
Cdd:TIGR02169 722 EKEIEQLEQEEEKLKERLEELE---------------------EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 547 YEKAVQHRNESGVQLIERE----EEICIFYEKINIQEKMKLNG-EIEIHLLEEKIQFLKMKIAEKQRQI---CVTQKLLP 618
Cdd:TIGR02169 781 LNDLEARLSHSRIPEIQAElsklEEEVSRIEARLREIEQKLNRlTLEKEYLEKEIQELQEQRIDLKEQIksiEKEIENLN 860
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217367999 619 A-KRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRarflpgkdltekEMIQKLDKLELQLAKKEEKLLE 690
Cdd:TIGR02169 861 GkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR------------ELERKIEELEAQIEKKRKRLSE 921
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
127-705 |
8.54e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.05 E-value: 8.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 127 LRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQtipvqigKEIEKITRKKVEMEK 206
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR-------EKLEKLKREINELKR 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 207 KKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELAREneatsltergildlnlr 286
Cdd:TIGR02169 407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ----------------- 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 287 nSLIDKQNYHDELSRKQREKERDfrnLRKMELLLKVSWDALRQTQAlhQRLLLEK-------IISEMESKLVEQQLAEE- 358
Cdd:TIGR02169 470 -ELYDLKEEYDRVEKELSKLQRE---LAEAEAQARASEERVRGGRA--VEEVLKAsiqgvhgTVAQLGSVGERYATAIEv 543
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 359 ------NKLLKEQENMKELVVNLL------RMTQIKIDEKEQKSK---------------DFLKAQQKYTNIVKEM---- 407
Cdd:TIGR02169 544 aagnrlNNVVVEDDAVAKEAIELLkrrkagRATFLPLNKMRDERRdlsilsedgvigfavDLVEFDPKYEPAFKYVfgdt 623
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 408 -------KAKDLEIRIH--------------------------------KKKKCEIYRRLREFAKLYDTIRNERNKFVNL 448
Cdd:TIGR02169 624 lvvedieAARRLMGKYRmvtlegelfeksgamtggsraprggilfsrsePAELQRLRERLEGLKRELSSLQSELRRIENR 703
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 449 LHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHA---NNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNN 525
Cdd:TIGR02169 704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSsleQEIENVKSELKELEARIEELEEDLHKLEEALND 783
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 526 IDR---------LANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKI 596
Cdd:TIGR02169 784 LEArlshsripeIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK 863
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367999 597 QFLKMKIAEKQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPdgENRARFLPGKDLTEKEMIQKLDK 676
Cdd:TIGR02169 864 EELEEELEELEAAL---RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK--RKRLSELKAKLEALEEELSEIED 938
|
650 660
....*....|....*....|....*....
gi 2217367999 677 LELQLAKKEEKLLEKDFIYEQVSRLTDRL 705
Cdd:TIGR02169 939 PKGEDEEIPEEELSLEDVQAELQRVEEEI 967
|
|
| |
