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Conserved domains on  [gi|2217288091|ref|XP_047284485|]
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R3H domain-containing protein 2 isoform X22 [Homo sapiens]

Protein Classification

R3H domain-containing protein( domain architecture ID 11552619)

R3H domain-containing protein with SUZ and Med15 domains, may bind ssDNA or ssRNA in a sequence-specific manner; similar to Mus musculus R3H domain-containing protein 2

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 168-229 1.50e-26

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


:

Pssm-ID: 100071  Cd Length: 63  Bit Score: 103.07  E-value: 1.50e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217288091 168 DRMMLLKLEQEILEFINDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTG-KAVIINKT 229
Cdd:cd02642     1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
SUZ pfam12752
SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched ...
 250-303 3.45e-12

SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched in positively charged amino acids. It was first characterized in the C.elegans protein Szy-20 where it has been shown to bind RNA and allow their localization to the centrosome. Warning- the domain has a compositionally biased character.


:

Pssm-ID: 463689 [Multi-domain]  Cd Length: 56  Bit Score: 61.95  E-value: 3.45e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217288091 250 EFQQRFILKRDDASMD--RDDNQIRVPLQDGRRSKSIEEREEEYQRVRERIFARET 303
Cdd:pfam12752   1 PPPKMKILRRPSSGSSssSSAGSSGASSSSGSDSKTLEEREAEYAEARARIFGSSE 56
Med15 super family cl26621
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 457-722 4.44e-09

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


The actual alignment was detected with superfamily member pfam09606:

Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 60.41  E-value: 4.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 457 GQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSFIMASTGQPLPTSNYSTSSHAPPTQQVLPPQGYMQppQQIQVSYYP 536
Cdd:pfam09606 186 GGMNGGQQGPMGGQMPPQMGVPGMPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQ--SQLGMGINQ 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 537 PGQYPNSNQQYRPLSHPVAY--SPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGL 614
Cdd:pfam09606 264 MQQMPQGVGGGAGQGGPGQPmgPPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVAL 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 615 VVQYTPLPSYQVPVGSDSQNVVQP--PFQQPMLVPVS----QSVQG--GLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPP 686
Cdd:pfam09606 344 GGLNHLETWNPGNFGGLGANPMQRgqPGMMSSPSPVPgqqvRQVTPnqFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSP 423

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2217288091 687 GSEQYQMPQSPSPCSPPQMPQQYSGVSPSG-PGVVVM 722
Cdd:pfam09606 424 ALIPSPSPQMSQQPAQQRTIGQDSPGGSLNtPGQSAV 460
 
Name Accession Description Interval E-value
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 168-229 1.50e-26

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 103.07  E-value: 1.50e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217288091 168 DRMMLLKLEQEILEFINDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTG-KAVIINKT 229
Cdd:cd02642     1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
R3H smart00393
Putative single-stranded nucleic acids-binding domain;
152-229 5.62e-14

Putative single-stranded nucleic acids-binding domain;


Pssm-ID: 214647  Cd Length: 79  Bit Score: 67.71  E-value: 5.62e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  152 IDLHEFLVNTLKKNPRDRMMLLKLEQEILEFINdNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKA--VIINKT 229
Cdd:smart00393   1 ADFLPVTLDALSYRPRRREELIELELEIARFVK-STKESVELPPMNSYERKIVHELAEKYGLESESFGEGPKrrVVISKK 79
SUZ pfam12752
SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched ...
 250-303 3.45e-12

SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched in positively charged amino acids. It was first characterized in the C.elegans protein Szy-20 where it has been shown to bind RNA and allow their localization to the centrosome. Warning- the domain has a compositionally biased character.


Pssm-ID: 463689 [Multi-domain]  Cd Length: 56  Bit Score: 61.95  E-value: 3.45e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217288091 250 EFQQRFILKRDDASMD--RDDNQIRVPLQDGRRSKSIEEREEEYQRVRERIFARET 303
Cdd:pfam12752   1 PPPKMKILRRPSSGSSssSSAGSSGASSSSGSDSKTLEEREAEYAEARARIFGSSE 56
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
 170-228 2.28e-10

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 57.12  E-value: 2.28e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217288091 170 MMLLKLEQEILEFINDNNNQFKkFPQMTSYHRMLLHRVAAYFGMDHNV--DQTGKAVIINK 228
Cdd:pfam01424   1 EFLEQLAEKLAEFVKDTGKSLE-LPPMSSYERRIIHELAQKYGLESESegEEPNRRVVVYK 60
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 457-722 4.44e-09

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 60.41  E-value: 4.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 457 GQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSFIMASTGQPLPTSNYSTSSHAPPTQQVLPPQGYMQppQQIQVSYYP 536
Cdd:pfam09606 186 GGMNGGQQGPMGGQMPPQMGVPGMPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQ--SQLGMGINQ 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 537 PGQYPNSNQQYRPLSHPVAY--SPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGL 614
Cdd:pfam09606 264 MQQMPQGVGGGAGQGGPGQPmgPPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVAL 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 615 VVQYTPLPSYQVPVGSDSQNVVQP--PFQQPMLVPVS----QSVQG--GLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPP 686
Cdd:pfam09606 344 GGLNHLETWNPGNFGGLGANPMQRgqPGMMSSPSPVPgqqvRQVTPnqFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSP 423

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2217288091 687 GSEQYQMPQSPSPCSPPQMPQQYSGVSPSG-PGVVVM 722
Cdd:pfam09606 424 ALIPSPSPQMSQQPAQQRTIGQDSPGGSLNtPGQSAV 460
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 472-623 1.22e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.76  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  472 PSAALFqTPLISqhPQQTSfimasTGQPLPTSNYSTSSH-APPTQQVLPPQGYMQPPQQiqvsYYPPGQYPNSNQQYRPL 550
Cdd:PRK10263   740 PHEPLF-TPIVE--PVQQP-----QQPVAPQQQYQQPQQpVAPQPQYQQPQQPVAPQPQ----YQQPQQPVAPQPQYQQP 807

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217288091  551 SHPVAYSPQRGqqlpqpsqqpglQPMMPNQQQAAYqgmigvQQPQNQGLLSSQRSSM------GGQMQGLVVQYTPLPS 623
Cdd:PRK10263   808 QQPVAPQPQYQ------------QPQQPVAPQPQY------QQPQQPVAPQPQDTLLhpllmrNGDSRPLHKPTTPLPS 868
 
Name Accession Description Interval E-value
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 168-229 1.50e-26

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 103.07  E-value: 1.50e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217288091 168 DRMMLLKLEQEILEFINDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTG-KAVIINKT 229
Cdd:cd02642     1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
R3H smart00393
Putative single-stranded nucleic acids-binding domain;
152-229 5.62e-14

Putative single-stranded nucleic acids-binding domain;


Pssm-ID: 214647  Cd Length: 79  Bit Score: 67.71  E-value: 5.62e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  152 IDLHEFLVNTLKKNPRDRMMLLKLEQEILEFINdNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKA--VIINKT 229
Cdd:smart00393   1 ADFLPVTLDALSYRPRRREELIELELEIARFVK-STKESVELPPMNSYERKIVHELAEKYGLESESFGEGPKrrVVISKK 79
SUZ pfam12752
SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched ...
 250-303 3.45e-12

SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched in positively charged amino acids. It was first characterized in the C.elegans protein Szy-20 where it has been shown to bind RNA and allow their localization to the centrosome. Warning- the domain has a compositionally biased character.


Pssm-ID: 463689 [Multi-domain]  Cd Length: 56  Bit Score: 61.95  E-value: 3.45e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217288091 250 EFQQRFILKRDDASMD--RDDNQIRVPLQDGRRSKSIEEREEEYQRVRERIFARET 303
Cdd:pfam12752   1 PPPKMKILRRPSSGSSssSSAGSSGASSSSGSDSKTLEEREAEYAEARARIFGSSE 56
R3H cd02325
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most ...
 172-228 3.19e-11

R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich repeats, ring-type zinc fingers, and KH domains. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100064  Cd Length: 59  Bit Score: 59.55  E-value: 3.19e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217288091 172 LLKLEQEILEFINDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTG--KAVIINK 228
Cdd:cd02325     1 REEREEELEAFAKDAAGKSLELPPMNSYERKLIHDLAEYYGLKSESEGEGpnRRVVITK 59
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
 170-228 2.28e-10

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 57.12  E-value: 2.28e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217288091 170 MMLLKLEQEILEFINDNNNQFKkFPQMTSYHRMLLHRVAAYFGMDHNV--DQTGKAVIINK 228
Cdd:pfam01424   1 EFLEQLAEKLAEFVKDTGKSLE-LPPMSSYERRIIHELAQKYGLESESegEEPNRRVVVYK 60
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 457-722 4.44e-09

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 60.41  E-value: 4.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 457 GQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSFIMASTGQPLPTSNYSTSSHAPPTQQVLPPQGYMQppQQIQVSYYP 536
Cdd:pfam09606 186 GGMNGGQQGPMGGQMPPQMGVPGMPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQ--SQLGMGINQ 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 537 PGQYPNSNQQYRPLSHPVAY--SPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGL 614
Cdd:pfam09606 264 MQQMPQGVGGGAGQGGPGQPmgPPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVAL 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 615 VVQYTPLPSYQVPVGSDSQNVVQP--PFQQPMLVPVS----QSVQG--GLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPP 686
Cdd:pfam09606 344 GGLNHLETWNPGNFGGLGANPMQRgqPGMMSSPSPVPgqqvRQVTPnqFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSP 423

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2217288091 687 GSEQYQMPQSPSPCSPPQMPQQYSGVSPSG-PGVVVM 722
Cdd:pfam09606 424 ALIPSPSPQMSQQPAQQRTIGQDSPGGSLNtPGQSAV 460
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 498-633 2.42e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.03  E-value: 2.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091 498 QPLPTSNYSTSSHAPPTQQVLPPQGYMQPPQQIQvsyyPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMM 577
Cdd:pfam09770 211 AQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQ----QPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQ 286

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217288091 578 PNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQ 633
Cdd:pfam09770 287 QFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQ 342
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 472-623 1.22e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.76  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  472 PSAALFqTPLISqhPQQTSfimasTGQPLPTSNYSTSSH-APPTQQVLPPQGYMQPPQQiqvsYYPPGQYPNSNQQYRPL 550
Cdd:PRK10263   740 PHEPLF-TPIVE--PVQQP-----QQPVAPQQQYQQPQQpVAPQPQYQQPQQPVAPQPQ----YQQPQQPVAPQPQYQQP 807

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217288091  551 SHPVAYSPQRGqqlpqpsqqpglQPMMPNQQQAAYqgmigvQQPQNQGLLSSQRSSM------GGQMQGLVVQYTPLPS 623
Cdd:PRK10263   808 QQPVAPQPQYQ------------QPQQPVAPQPQY------QQPQQPVAPQPQDTLLhpllmrNGDSRPLHKPTTPLPS 868
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 448-689 1.95e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.38  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  448 QADDLSNPFGQMSLSRQGST-------EAADPSAALfQTPLISQ--HPQQTSFimaSTGQPLPTSNYSTSSHAPPTQQVL 518
Cdd:PRK10263   660 QQDELARQFAQTQQQRYGEQyqhdvpvNAEDADAAA-EAELARQfaQTQQQRY---SGEQPAGANPFSLDDFEFSPMKAL 735

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  519 PPQGYMQPpqqiqvsYYPPGQYPNSNQQYRPLSHPVAYSPQRgqqlPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQG 598
Cdd:PRK10263   736 LDDGPHEP-------LFTPIVEPVQQPQQPVAPQQQYQQPQQ----PVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQY 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  599 LLSSQrssmggqmqglvvQYTPLPSYQVPvgsDSQNVVQPPFQQPMlVPVSQSVQGGLpaagvpvyysMIPPAQQNGTS- 677
Cdd:PRK10263   805 QQPQQ-------------PVAPQPQYQQP---QQPVAPQPQYQQPQ-QPVAPQPQDTL----------LHPLLMRNGDSr 857

                          250       260
                   ....*....|....*....|.
gi 2217288091  678 ---------PSVGFLQPPGSE 689
Cdd:PRK10263   858 plhkpttplPSLDLLTPPPSE 878
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 498-665 5.24e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 5.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  498 QPLPTSNYSTSSHAPPTQQVLPPQGYMQPPQQIQVSY---YPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQ 574
Cdd:PRK10263   361 QPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLqqpVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQ 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  575 PMMPNQQQAAYQGMIGVQQPQNQgllssqrssmggqmqglvvqytPLPSYQVPVGSDSQNVVQPPFQQPMLV---PVSQS 651
Cdd:PRK10263   441 PVAGNAWQAEEQQSTFAPQSTYQ----------------------TEQTYQQPAAQEPLYQQPQPVEQQPVVepePVVEE 498

                          170
                   ....*....|....
gi 2217288091  652 VQGGLPaagvPVYY 665
Cdd:PRK10263   499 TKPARP----PLYY 508
PHA03377 PHA03377
EBNA-3C; Provisional
 478-682 7.57e-03

EBNA-3C; Provisional


Pssm-ID: 177614 [Multi-domain]  Cd Length: 1000  Bit Score: 40.42  E-value: 7.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  478 QTPL-ISQHPQQTsfimastgqPLPTSNYSTSSHAPPTQQVLPPQGYMQPP--------------QQIQVSYYPPGQYP- 541
Cdd:PHA03377   727 DDPLdLSLHPDQA---------PPPSHQAPYSGHEEPQAQQAPYPGYWEPRppqapylgyqepqaQGVQVSSYPGYAGPw 797

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217288091  542 NSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQqqaaYQGMIGVQQPQNQGLLSSQRSSMGGQMQGLVVQYTPL 621
Cdd:PHA03377   798 GLRAQHPRYRHSWAYWSQYPGHGHPQGPWAPRPPHLPPQ----WDGSAGHGQDQVSQFPHLQSETGPPRLQLSQVPQLPY 873

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217288091  622 PsyQVPVGSDSQNVVQPPFQQPMlvpvsQSVQGGLPAAGVPVYYSMIPPAQQNGTS-PSVGF 682
Cdd:PHA03377   874 S--QTLVSSSAPSWSSPQPRAPI-----RPIPTRFPPPPMPLQDSMAVGCDSSGTAcPSMPF 928
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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