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Conserved domains on  [gi|2217304432|ref|XP_047289498|]
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ataxin-2-like protein isoform X17 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 63-136 1.50e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


:

Pssm-ID: 464173  Cd Length: 78  Bit Score: 83.76  E-value: 1.50e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432  63 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVMLVHFR 136
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 204-266 1.43e-17

LsmAD domain; This domain is found associated with Lsm domain.


:

Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.43e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432 204 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 266
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 338-883 1.50e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.26  E-value: 1.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  338 ARGINGGPSRMSPKAQRPLRGAKTLSSPSNR--PSGETSVPPPPAVGRMYPPRSPKSAAPAPisASCPEPPIGSAV-PTS 414
Cdd:PHA03247  2456 ARTILGAPFSLSLLLGELFPGAPVYRRPAEArfPFAAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVhPRM 2533

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  415 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPG-RTLEPQELARiaGKVPGLQNEQKRFQLEELRKFGAQFK 493
Cdd:PHA03247  2534 LTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPApRPSEPAVTSR--ARRPDAPPQSARPRAPVDDRGDPRGP 2611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  494 LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS------------------DKEDKPPLAPS 555
Cdd:PHA03247  2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrprrarrlgraaqassppQRPRRRAARPT 2691

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  556 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP-VAEQVKKSTLNPNAKEFNPTKPLL--SVNKSTSTPTSPGPRTHST 632
Cdd:PHA03247  2692 VGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPaAARQASPALPAAPAPPAVPAGPATpgGPARPARPPTTAGPPAPAP 2771

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  633 PSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaa 712
Cdd:PHA03247  2772 PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG------ 2844

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  713 aagpplvaatPYSSYIPYNPQQFPGQPAMMQPMahyPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPSAEQPTP 790
Cdd:PHA03247  2845 ----------PPPPSLPLGGSVAPGGDVRRRPP---SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQP 2911

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  791 QAlyatvhqsyPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-P 869
Cdd:PHA03247  2912 QA---------PPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqP 2982

                          570
                   ....*....|....
gi 2217304432  870 GPSAQSPQSSFPQP 883
Cdd:PHA03247  2983 APSREAPASSTPPL 2996
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 63-136 1.50e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 83.76  E-value: 1.50e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432  63 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVMLVHFR 136
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 204-266 1.43e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.43e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432 204 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 266
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PHA03247 PHA03247
large tegument protein UL36; Provisional
 338-883 1.50e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.26  E-value: 1.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  338 ARGINGGPSRMSPKAQRPLRGAKTLSSPSNR--PSGETSVPPPPAVGRMYPPRSPKSAAPAPisASCPEPPIGSAV-PTS 414
Cdd:PHA03247  2456 ARTILGAPFSLSLLLGELFPGAPVYRRPAEArfPFAAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVhPRM 2533

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  415 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPG-RTLEPQELARiaGKVPGLQNEQKRFQLEELRKFGAQFK 493
Cdd:PHA03247  2534 LTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPApRPSEPAVTSR--ARRPDAPPQSARPRAPVDDRGDPRGP 2611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  494 LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS------------------DKEDKPPLAPS 555
Cdd:PHA03247  2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrprrarrlgraaqassppQRPRRRAARPT 2691

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  556 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP-VAEQVKKSTLNPNAKEFNPTKPLL--SVNKSTSTPTSPGPRTHST 632
Cdd:PHA03247  2692 VGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPaAARQASPALPAAPAPPAVPAGPATpgGPARPARPPTTAGPPAPAP 2771

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  633 PSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaa 712
Cdd:PHA03247  2772 PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG------ 2844

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  713 aagpplvaatPYSSYIPYNPQQFPGQPAMMQPMahyPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPSAEQPTP 790
Cdd:PHA03247  2845 ----------PPPPSLPLGGSVAPGGDVRRRPP---SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQP 2911

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  791 QAlyatvhqsyPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-P 869
Cdd:PHA03247  2912 QA---------PPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqP 2982

                          570
                   ....*....|....
gi 2217304432  870 GPSAQSPQSSFPQP 883
Cdd:PHA03247  2983 APSREAPASSTPPL 2996
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 731-977 8.96e-08

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 56.20  E-value: 8.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 731 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPSAEQPTPQALYAT 796
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 797 VHQSYPHHAT------QLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYH---PGALTGTPPSL 867
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQqpqQHPGQGHPVTI 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 868 PPGPSAQSPQSSFPQPAAVYAIHHQQLPhgfTNMAHVTQAhvqtgitaappphpGAPHPPQVMLLHPPQSHGGPPQGAVP 947
Cdd:pfam09770 266 LQRPQSPQPDPAQPSIQPQAQQFHQQPP---PVPVQPTQI--------------LQNPNRLSAARVGYPQNPQPGVQPAP 328

                         250       260       270
                  ....*....|....*....|....*....|
gi 2217304432 948 QSGVPALSASTPSPYPYIGHPQVQSHPSQQ 977
Cdd:pfam09770 329 AHQAHRQQGSFGRQAPIITHPQQLAQLSEE 358
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 755-892 6.97e-03

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 40.18  E-value: 6.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 755 APMLQSNPRMLTSGSHPQaivssstPQYpsaEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPV 834
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQ-------PPY---YGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPLRPNGLAPMNAVRAPSRN 449

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432 835 QQHQAGQAPhlgsgqpqqnlyhpgaltgtPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 892
Cdd:TIGR01628 450 AQNAAQKPP--------------------MQPVMYPPNYQSLPLSQDLPQPQSTASQG 487
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 63-136 1.50e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 83.76  E-value: 1.50e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432  63 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVMLVHFR 136
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 204-266 1.43e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.43e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432 204 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 266
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PHA03247 PHA03247
large tegument protein UL36; Provisional
 338-883 1.50e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.26  E-value: 1.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  338 ARGINGGPSRMSPKAQRPLRGAKTLSSPSNR--PSGETSVPPPPAVGRMYPPRSPKSAAPAPisASCPEPPIGSAV-PTS 414
Cdd:PHA03247  2456 ARTILGAPFSLSLLLGELFPGAPVYRRPAEArfPFAAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVhPRM 2533

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  415 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPG-RTLEPQELARiaGKVPGLQNEQKRFQLEELRKFGAQFK 493
Cdd:PHA03247  2534 LTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPApRPSEPAVTSR--ARRPDAPPQSARPRAPVDDRGDPRGP 2611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  494 LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS------------------DKEDKPPLAPS 555
Cdd:PHA03247  2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrprrarrlgraaqassppQRPRRRAARPT 2691

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  556 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP-VAEQVKKSTLNPNAKEFNPTKPLL--SVNKSTSTPTSPGPRTHST 632
Cdd:PHA03247  2692 VGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPaAARQASPALPAAPAPPAVPAGPATpgGPARPARPPTTAGPPAPAP 2771

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  633 PSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaa 712
Cdd:PHA03247  2772 PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG------ 2844

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  713 aagpplvaatPYSSYIPYNPQQFPGQPAMMQPMahyPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPSAEQPTP 790
Cdd:PHA03247  2845 ----------PPPPSLPLGGSVAPGGDVRRRPP---SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQP 2911

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  791 QAlyatvhqsyPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-P 869
Cdd:PHA03247  2912 QA---------PPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqP 2982

                          570
                   ....*....|....
gi 2217304432  870 GPSAQSPQSSFPQP 883
Cdd:PHA03247  2983 APSREAPASSTPPL 2996
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 731-977 8.96e-08

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 56.20  E-value: 8.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 731 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPSAEQPTPQALYAT 796
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 797 VHQSYPHHAT------QLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYH---PGALTGTPPSL 867
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQqpqQHPGQGHPVTI 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 868 PPGPSAQSPQSSFPQPAAVYAIHHQQLPhgfTNMAHVTQAhvqtgitaappphpGAPHPPQVMLLHPPQSHGGPPQGAVP 947
Cdd:pfam09770 266 LQRPQSPQPDPAQPSIQPQAQQFHQQPP---PVPVQPTQI--------------LQNPNRLSAARVGYPQNPQPGVQPAP 328

                         250       260       270
                  ....*....|....*....|....*....|
gi 2217304432 948 QSGVPALSASTPSPYPYIGHPQVQSHPSQQ 977
Cdd:pfam09770 329 AHQAHRQQGSFGRQAPIITHPQQLAQLSEE 358
PHA03247 PHA03247
large tegument protein UL36; Provisional
 276-790 7.35e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.79  E-value: 7.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  276 GRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP-----------GSEARGINGG 344
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPrpaprpsepavTSRARRPDAP 2592

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  345 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRmyPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 424
Cdd:PHA03247  2593 PQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP--SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRL 2670

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  425 SDPGVGSISPASPKISLAPTDVKELST----KEPGRTLEPQELARIAGKVPGLQNEQKRfqleelrkfgaqfklqpSSSP 500
Cdd:PHA03247  2671 GRAAQASSPPQRPRRRAARPTVGSLTSladpPPPPPTPEPAPHALVSATPLPPGPAAAR-----------------QASP 2733

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  501 ENSLDPFPPrilkeePKGKEKEVDGllTSEPMGSPVSSKTESVSdkedKPPLAPSGGTEGPEQPPPPCPSQTGSPpvGLI 580
Cdd:PHA03247  2734 ALPAAPAPP------AVPAGPATPG--GPARPARPPTTAGPPAP----APPAAPAAGPPRRLTRPAVASLSESRE--SLP 2799

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  581 KGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPllsvnKSTSTPTSPGPRthSTPSIPVLTAGqsGLYSPQyisyipqihmG 660
Cdd:PHA03247  2800 SPWDPADPPAAVLAPAAALPPAASPAGPLPP-----PTSAQPTAPPPP--PGPPPPSLPLG--GSVAPG----------G 2860

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  661 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP- 739
Cdd:PHA03247  2861 DVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPq 2940

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217304432  740 AMMQPMAHYPSQPVFAPMLqSNPRM--LTSGSH--PQAIVSSSTPQYPSAEQPTP 790
Cdd:PHA03247  2941 PPLAPTTDPAGAGEPSGAV-PQPWLgaLVPGRVavPRFRVPQPAPSREAPASSTP 2994
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 749-880 3.68e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 51.24  E-value: 3.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  749 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP-----QYPSAEQPT-PQALYATVHQSYPHHATQLHAHQPQpATTPTGS 822
Cdd:PRK10263   740 PHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPvapqpQYQQPQQPVaPQPQYQQPQQPVAPQPQYQQPQQPV-APQPQYQ 818

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217304432  823 QPQSQHAAPSPVQQHQAGQAPhlgsgQPQQNLYHPGALTG----------TP-PS---LPPGPSAQSPQSSF 880
Cdd:PRK10263   819 QPQQPVAPQPQYQQPQQPVAP-----QPQDTLLHPLLMRNgdsrplhkptTPlPSldlLTPPPSEVEPVDTF 885
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 592-896 2.80e-05

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 48.11  E-value: 2.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 592 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPrthSTPSIPVLTagqsGLYSPQYISYIPQIH-------MGPAVQ 664
Cdd:pfam09770  98 EQVRFNRQQPAARAAQSSAQPPASSLPQYQYASQQS---QQPSKPVRT----GYEKYKEPEPIPDLQvdaslwgVAPKKA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 665 APQMYPYPVSNSVPGQQGKYR---------------GAKGSLPPQRSDQHQPASAPPMMQAAaaagpplvaatpyssyiP 729
Cdd:pfam09770 171 AAPAPAPQPAAQPASLPAPSRkmmsleeveaamraqAKKPAQQPAPAPAQPPAAPPAQQAQQ-----------------Q 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 730 YNPQQFPGQPAMMQPMAHYPSQPvfapmlqsnprmlTSGSHPQAIVssstpQYPSAEQPTPqalyatvhqsyphhatqlh 809
Cdd:pfam09770 234 QQFPPQIQQQQQPQQQPQQPQQH-------------PGQGHPVTIL-----QRPQSPQPDP------------------- 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 810 aHQPQPattPTGSQPQSQHAAPSPVQQHQAGQAPHLGSgqPQQNLYHPGALTGTPPslPPGPSAQSPQSSFPQPAAVYAi 889
Cdd:pfam09770 277 -AQPSI---QPQAQQFHQQPPPVPVQPTQILQNPNRLS--AARVGYPQNPQPGVQP--APAHQAHRQQGSFGRQAPIIT- 347


                  ....*..
gi 2217304432 890 HHQQLPH 896
Cdd:pfam09770 348 HPQQLAQ 354
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 314-636 3.92e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 44.30  E-value: 3.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 314 PGLSSLPPRGPHHLDNSS----PGPGSEARGINGGPSRMSP----KAQRPLRGAKTLSSP--SNRPSGETSVPPPPavgR 383
Cdd:PTZ00449  514 PEASGLPPKAPGDKEGEEgeheDSKESDEPKEGGKPGETKEgevgKKPGPAKEHKPSKIPtlSKKPEFPKDPKHPK---D 590

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 384 MYPPRSPKS--AAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPgVGSISPASPKISLAPTDVKE-LSTKEPGRTLEP 460
Cdd:PTZ00449  591 PEEPKKPKRprSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRP-PPPQRPSSPERPEGPKIIKSpKPPKSPKPPFDP 669

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 461 ---QELARIAGKVPGLQNEQKRFQL--EELRKFGAQFKLQPSSSPENSLDPFPPRIlkeepkgkekEVDGLLTSEPMGSP 535
Cdd:PTZ00449  670 kfkEKFYDDYLDAAAKSKETKTTVVldESFESILKETLPETPGTPFTTPRPLPPKL----------PRDEEFPFEPIGDP 739

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 536 VSsktESVSDKE-DKPPLAPSggtegpeqpPPPCPSQTGSPPVGLIKGEDKDEGPVAEqvkksTLNPNAKEFNPTKPlls 614
Cdd:PTZ00449  740 DA---EQPDDIEfFTPPEEER---------TFFHETPADTPLPDILAEEFKEEDIHAE-----TGEPDEAMKRPDSP--- 799

                         330       340
                  ....*....|....*....|..
gi 2217304432 615 vnkSTSTPTSPGprTHstPSIP 636
Cdd:PTZ00449  800 ---SEHEDKPPG--DH--PSLP 814
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
810-886 4.30e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 44.00  E-value: 4.30e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217304432 810 AHQPQPATTPTGSQPQSqHAAPSPVQQHQAGQAphlgSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 886
Cdd:PRK14971  389 APQPSAAAAASPSPSQS-SAAAQPSAPQSATQP----AGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPV 460
PHA03247 PHA03247
large tegument protein UL36; Provisional
 272-472 2.57e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  272 RQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHH-------------LDNSSPGPGSEA 338
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRraarptvgsltslADPPPPPPTPEP 2710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  339 RGINGGPSRMSPKAQRPLRGAK--TLSSPSNRPSGETSVPP-----------PPAVGRMYPPRSPKSAAP--APISASCP 403
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASpaLPAAPAPPAVPAGPATPggparparpptTAGPPAPAPPAAPAAGPPrrLTRPAVAS 2790

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217304432  404 EPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPG 472
Cdd:PHA03247  2791 LSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG 2859
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
299-468 2.77e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.76  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 299 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPS-NRPSGETSVPP 377
Cdd:PRK07003  366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPaTADRGDDAADG 445

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 378 PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT 457
Cdd:PRK07003  446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAA 525

                         170
                  ....*....|.
gi 2217304432 458 LEPQELARIAG 468
Cdd:PRK07003  526 APPAPEARPPT 536
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
335-492 3.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 41.30  E-value: 3.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 335 GSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS-GETSVPPPPAvgrmypprspksaAPAPISASCPEPPIGSAVPT 413
Cdd:PRK14971  366 GDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSpSQSSAAAQPS-------------APQSATQPAGTPPTVSVDPP 432

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217304432 414 SSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRtlEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF 492
Cdd:PRK14971  433 AAVPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQ--EKAEQATGNIKEAPTGTQKEIFTEEDLQYYWQEF 509
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 334-495 4.71e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.85  E-value: 4.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 334 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPsnRPSGETSVPPPPAVGRMYPPRSP-----KSAAPAPISASCPEPPIG 408
Cdd:PRK14951  374 APAEKKTPARPEAAAPAAAPVAQAAAAPAPAA--APAAAASAPAAPPAAAPPAPVAApaaaaPAAAPAAAPAAVALAPAP 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 409 SAVPTSSASIPVTSSVSDPGVGS----ISPASPKISLAPTD--------VKELSTKEPGRTLePQELAriagkvpgLQNE 476
Cdd:PRK14951  452 PAQAAPETVAIPVRVAPEPAVASaapaPAAAPAAARLTPTEegdvwhatVQQLAAAEAITAL-ARELA--------LQSE 522

                         170       180
                  ....*....|....*....|....*...
gi 2217304432 477 ---------QKRFQLEELRKFGAQFKLQ 495
Cdd:PRK14951  523 lvardgdqwLLRVERESLNQPGARERLR 550
PHA03247 PHA03247
large tegument protein UL36; Provisional
 427-983 4.92e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 4.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  427 PGVGSISPASPKISLAPTDVKE--LSTKEPGRTLEPQELARIAGkvpglqneqkrfqLEELrkfgaqfklqpssSPENSL 504
Cdd:PHA03247  2496 PDPGGGGPPDPDAPPAPSRLAPaiLPDEPVGEPVHPRMLTWIRG-------------LEEL-------------ASDDAG 2549

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  505 DPFPPRILKEEPKGKEKEVDgllTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGED 584
Cdd:PHA03247  2550 DPPPPLPPAAPPAAPDRSVP---PPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDP 2626

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  585 KDEGPVA------EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPgPRTHSTPSIPVLTAGQSGLYSPQYISYIPqih 658
Cdd:PHA03247  2627 PPPSPSPaanepdPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-AQASSPPQRPRRRAARPTVGSLTSLADPP--- 2702

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  659 mgPAVQAPQMYPYPVSNSVPGQQGKyRGAKGSLPPQRSDQHQPASAPPMMqaaaaagpplvaaTPYSSYIPYNPQQFPGQ 738
Cdd:PHA03247  2703 --PPPPTPEPAPHALVSATPLPPGP-AAARQASPALPAAPAPPAVPAGPA-------------TPGGPARPARPPTTAGP 2766

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  739 PAMMQPMAhypsqPVFAPmlqsnPRMLTSGshPQAIVSSSTPQYPSAEQPTPqalyATVHQSYPHHATQLHAHQPQPATT 818
Cdd:PHA03247  2767 PAPAPPAA-----PAAGP-----PRRLTRP--AVASLSESRESLPSPWDPAD----PPAAVLAPAAALPPAASPAGPLPP 2830

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  819 PTGSQPQSQHAAPSPVQQHQ------AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPaavyaihhQ 892
Cdd:PHA03247  2831 PTSAQPTAPPPPPGPPPPSLplggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALP--------P 2902

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  893 QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQS 972
Cdd:PHA03247  2903 DQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP 2982

                          570
                   ....*....|.
gi 2217304432  973 HPSQQLPFHPP 983
Cdd:PHA03247  2983 APSREAPASST 2993
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 768-886 5.47e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 5.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 768 GSHPQAIVSSSTPQYPSAeQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQ-PQSQHAAPSPVQQHQAGQAPHLG 846
Cdd:PRK07764  391 AGAPAAAAPSAAAAAPAA-APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAgNAPAGGAPSPPPAAAPSAQPAPA 469

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2217304432 847 SGQPQQNLYHPGAltGTPPSLPPGPSAQSPQSSFPQPAAV 886
Cdd:PRK07764  470 PAAAPEPTAAPAP--APPAAPAPAAAPAAPAAPAAPAGAD 507
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 267-428 5.69e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 5.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  267 HSAVQRQGSGRESPSLASREGKyIPLPQRVREGPRGGVRcssSRGGRPGLSSLPPRGPHhldnSSPGPGSEARGINGGPS 346
Cdd:PHA03307   241 SSESSGCGWGPENECPLPRPAP-ITLPTRIWEASGWNGP---SSRPGPASSSSSPRERS----PSPSPSSPGSGPAPSSP 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432  347 RMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS-AAPAPISASCPEPPIGSAVPTSSASIPVTSSVS 425
Cdd:PHA03307   313 RASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPpADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392


                   ...
gi 2217304432  426 DPG 428
Cdd:PHA03307   393 AVA 395
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 755-892 6.97e-03

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 40.18  E-value: 6.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 755 APMLQSNPRMLTSGSHPQaivssstPQYpsaEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPV 834
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQ-------PPY---YGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPLRPNGLAPMNAVRAPSRN 449

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432 835 QQHQAGQAPhlgsgqpqqnlyhpgaltgtPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 892
Cdd:TIGR01628 450 AQNAAQKPP--------------------MQPVMYPPNYQSLPLSQDLPQPQSTASQG 487
PRK10927 PRK10927
cell division protein FtsN;
781-885 9.15e-03

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 39.28  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 781 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQhQAGQAPHLGSGQPQQNLYHPGAL 860
Cdd:PRK10927  138 EVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQA-QPRQSKPASTQQPYQDLLQTPAH 216

                          90       100
                  ....*....|....*....|....*.
gi 2217304432 861 TGTPPSLP-PGPSAQSPQSsfPQPAA 885
Cdd:PRK10927  217 TTAQSKPQqAAPVTRAADA--PKPTA 240
PHA03369 PHA03369
capsid maturational protease; Provisional
 336-649 9.28e-03

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 39.98  E-value: 9.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 336 SEARGINGGPSRMSPKAQRPLRGAKTLSSPSnRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTss 415
Cdd:PHA03369  355 APSRVLAAAAKVAVIAAPQTHTGPADRQRPQ-RPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSPYNPQSPGTSYGPE-- 431

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 416 asiPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEP--QELARIAGKVPGL--QNEQKRFQLEELRKFGAQ 491
Cdd:PHA03369  432 ---PVGPVPPQPTNPYVMPISMANMVYPGHPQEHGHERKRKRGGElkEELIETLKLVKKLkeEQESLAKELEATAHKSEI 508

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304432 492 fklqpSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 571
Cdd:PHA03369  509 -----KKIAESEFKNAGAKTAAANIEPNCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSFTSTTLAAAA 583

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217304432 572 TGSPpvgliKGEDKDEGPVAEQVKKSTLNPnaKEFNPTKPLLSVNKSTSTPTSPgPRTHSTPSIPVLTAGQSGLYSPQ 649
Cdd:PHA03369  584 GQGS-----DTAEALAGAIETLLTQASAQP--AGLSLPAPAVPVNASTPASTPP-PLAPQEPPQPGTSAPSLETSLPQ 653
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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