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AP-4 complex subunit beta-1 isoform X11 [Homo sapiens]
adaptin family protein( domain architecture ID 13560656)
adaptin family protein is involved in the formation of clathrin-coated pits and vesicles, similar to human AP-4 complex subunit beta-1
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
B2-adapt-app_C | pfam09066 | Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure ... |
296-406 | 2.80e-33 | |||
Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure consisting of a 5 stranded beta-sheet, flanked by one alpha helix on the outer side, and by two alpha helices on the inner side. This domain is required for binding to clathrin, and its subsequent polymerization. Furthermore, a hydrophobic patch present in the domain also binds to a subset of D-phi-F/W motif-containing proteins that are bound by the alpha-adaptin appendage domain (epsin, AP180, eps15). : Pssm-ID: 462667 Cd Length: 111 Bit Score: 120.83 E-value: 2.80e-33
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Adaptin_N super family | cl37648 | Adaptin N terminal region; This family consists of the N terminal region of various alpha, ... |
55-200 | 3.14e-10 | |||
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles. The actual alignment was detected with superfamily member pfam01602: Pssm-ID: 396262 [Multi-domain] Cd Length: 523 Bit Score: 61.87 E-value: 3.14e-10
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Name | Accession | Description | Interval | E-value | |||
B2-adapt-app_C | pfam09066 | Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure ... |
296-406 | 2.80e-33 | |||
Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure consisting of a 5 stranded beta-sheet, flanked by one alpha helix on the outer side, and by two alpha helices on the inner side. This domain is required for binding to clathrin, and its subsequent polymerization. Furthermore, a hydrophobic patch present in the domain also binds to a subset of D-phi-F/W motif-containing proteins that are bound by the alpha-adaptin appendage domain (epsin, AP180, eps15). Pssm-ID: 462667 Cd Length: 111 Bit Score: 120.83 E-value: 2.80e-33
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B2-adapt-app_C | smart01020 | Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure ... |
295-407 | 3.49e-31 | |||
Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure consisting of a 5 stranded beta-sheet, flanked by one alpha helix on the outer side, and by two alpha helices on the inner side. This domain is required for binding to clathrin, and its subsequent polymerisation. Furthermore, a hydrophobic patch present in the domain also binds to a subset of D-phi-F/W motif-containing proteins that are bound by the alpha-adaptin appendage domain (epsin, AP180, eps15). Pssm-ID: 198088 Cd Length: 111 Bit Score: 115.10 E-value: 3.49e-31
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Adaptin_N | pfam01602 | Adaptin N terminal region; This family consists of the N terminal region of various alpha, ... |
55-200 | 3.14e-10 | |||
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles. Pssm-ID: 396262 [Multi-domain] Cd Length: 523 Bit Score: 61.87 E-value: 3.14e-10
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PTZ00429 | PTZ00429 | beta-adaptin; Provisional |
57-208 | 6.57e-05 | |||
beta-adaptin; Provisional Pssm-ID: 240415 [Multi-domain] Cd Length: 746 Bit Score: 45.31 E-value: 6.57e-05
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COG5096 | COG5096 | Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ... |
115-212 | 2.65e-03 | |||
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]; Pssm-ID: 227427 [Multi-domain] Cd Length: 757 Bit Score: 40.10 E-value: 2.65e-03
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Name | Accession | Description | Interval | E-value | |||
B2-adapt-app_C | pfam09066 | Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure ... |
296-406 | 2.80e-33 | |||
Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure consisting of a 5 stranded beta-sheet, flanked by one alpha helix on the outer side, and by two alpha helices on the inner side. This domain is required for binding to clathrin, and its subsequent polymerization. Furthermore, a hydrophobic patch present in the domain also binds to a subset of D-phi-F/W motif-containing proteins that are bound by the alpha-adaptin appendage domain (epsin, AP180, eps15). Pssm-ID: 462667 Cd Length: 111 Bit Score: 120.83 E-value: 2.80e-33
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B2-adapt-app_C | smart01020 | Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure ... |
295-407 | 3.49e-31 | |||
Beta2-adaptin appendage, C-terminal sub-domain; Members of this family adopt a structure consisting of a 5 stranded beta-sheet, flanked by one alpha helix on the outer side, and by two alpha helices on the inner side. This domain is required for binding to clathrin, and its subsequent polymerisation. Furthermore, a hydrophobic patch present in the domain also binds to a subset of D-phi-F/W motif-containing proteins that are bound by the alpha-adaptin appendage domain (epsin, AP180, eps15). Pssm-ID: 198088 Cd Length: 111 Bit Score: 115.10 E-value: 3.49e-31
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Adaptin_N | pfam01602 | Adaptin N terminal region; This family consists of the N terminal region of various alpha, ... |
55-200 | 3.14e-10 | |||
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles. Pssm-ID: 396262 [Multi-domain] Cd Length: 523 Bit Score: 61.87 E-value: 3.14e-10
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PTZ00429 | PTZ00429 | beta-adaptin; Provisional |
57-208 | 6.57e-05 | |||
beta-adaptin; Provisional Pssm-ID: 240415 [Multi-domain] Cd Length: 746 Bit Score: 45.31 E-value: 6.57e-05
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COG5096 | COG5096 | Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ... |
115-212 | 2.65e-03 | |||
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]; Pssm-ID: 227427 [Multi-domain] Cd Length: 757 Bit Score: 40.10 E-value: 2.65e-03
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Blast search parameters | ||||
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