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Conserved domains on  [gi|2217324070|ref|XP_047295712|]
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zinc finger protein 254 isoform X4 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
179-540 1.12e-10

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 1.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 179 KLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKC--EECGKAFIWSSTLTEHKKIHTRKKPYKCE-ECGKAFIWSSTLTRH 255
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 256 KRMHTGEKPYKCEECGKAFSQSSTLT--THKIIHTGEKRYK---------------------CLECGKAFKQLSTLTTHK 312
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgnnsssvntpqsnslhpplpaNSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 313 IIHVGEKLYKCEECGKgFNRSSNLTTHKIIHTGEKPYKCEECGKAF-----IWSSTLTKHKRIHTREKP-YKCEECGKAF 386
Cdd:COG5048   192 VSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllSQSPSSLSSSDSSSSASEsPRSSLPTASS 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 387 IWSSTLTRHKRMHTG-EKPYKCEECGKSFSQSSTLTTHK--IIHTGE--KPYKCEE--CGKAFNWSSTLTKHKIIHTEEK 459
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 460 PYKC--EKCGKAFKQSSI-----LTNHKRIHTGEKPYKCE--ECGKSFNRSSTFTKHKVIHTGVKP--YKCEECGKAFFW 528
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNR 430

                         410
                  ....*....|..
gi 2217324070 529 SSTLTKHKRIHT 540
Cdd:COG5048   431 HYNLIPHKKIHT 442
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
179-540 1.12e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 1.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 179 KLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKC--EECGKAFIWSSTLTEHKKIHTRKKPYKCE-ECGKAFIWSSTLTRH 255
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 256 KRMHTGEKPYKCEECGKAFSQSSTLT--THKIIHTGEKRYK---------------------CLECGKAFKQLSTLTTHK 312
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgnnsssvntpqsnslhpplpaNSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 313 IIHVGEKLYKCEECGKgFNRSSNLTTHKIIHTGEKPYKCEECGKAF-----IWSSTLTKHKRIHTREKP-YKCEECGKAF 386
Cdd:COG5048   192 VSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllSQSPSSLSSSDSSSSASEsPRSSLPTASS 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 387 IWSSTLTRHKRMHTG-EKPYKCEECGKSFSQSSTLTTHK--IIHTGE--KPYKCEE--CGKAFNWSSTLTKHKIIHTEEK 459
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 460 PYKC--EKCGKAFKQSSI-----LTNHKRIHTGEKPYKCE--ECGKSFNRSSTFTKHKVIHTGVKP--YKCEECGKAFFW 528
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNR 430

                         410
                  ....*....|..
gi 2217324070 529 SSTLTKHKRIHT 540
Cdd:COG5048   431 HYNLIPHKKIHT 442
zf-H2C2_2 pfam13465
Zinc-finger double domain;
392-416 1.47e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.47e-04
                          10        20
                  ....*....|....*....|....*
gi 2217324070 392 LTRHKRMHTGEKPYKCEECGKSFSQ 416
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
179-540 1.12e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 1.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 179 KLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKC--EECGKAFIWSSTLTEHKKIHTRKKPYKCE-ECGKAFIWSSTLTRH 255
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 256 KRMHTGEKPYKCEECGKAFSQSSTLT--THKIIHTGEKRYK---------------------CLECGKAFKQLSTLTTHK 312
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgnnsssvntpqsnslhpplpaNSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 313 IIHVGEKLYKCEECGKgFNRSSNLTTHKIIHTGEKPYKCEECGKAF-----IWSSTLTKHKRIHTREKP-YKCEECGKAF 386
Cdd:COG5048   192 VSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllSQSPSSLSSSDSSSSASEsPRSSLPTASS 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 387 IWSSTLTRHKRMHTG-EKPYKCEECGKSFSQSSTLTTHK--IIHTGE--KPYKCEE--CGKAFNWSSTLTKHKIIHTEEK 459
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 460 PYKC--EKCGKAFKQSSI-----LTNHKRIHTGEKPYKCE--ECGKSFNRSSTFTKHKVIHTGVKP--YKCEECGKAFFW 528
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNR 430

                         410
                  ....*....|..
gi 2217324070 529 SSTLTKHKRIHT 540
Cdd:COG5048   431 HYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
94-509 1.81e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.18  E-value: 1.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070  94 KKSFKCKKRVKLFCMLSHKTQHKSIYHREKSYKC--KECGKTFNWSSTLTNHRKIYTEEKPYKCEeyNKSPKQLSTLTTH 171
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS--KSLPLSNSKASSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 172 EIIHAGEKLYKCE-ECGEAFNRSSNLTTHKIIHTGEKPYKCEECGKAFIWSSTLTEHKKIHTRKKPykcEECGKAFIWSS 250
Cdd:COG5048   109 SLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 251 TLTRHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTgEKRYKCLECGKAFKQLST----LTTHKIIHVGEKLYKCEEC 326
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLsqspSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 327 G--KGFNRSSNLTTHKIIHTG-EKPYKCEECGKAFIWSSTLTKHKR--IHTRE--KPYKCEE--CGKAFIWSSTLTRHKR 397
Cdd:COG5048   265 LptASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 398 MHTGEKPYKC--EECGKSFSQSST-----LTTHKIIHTGEKPYKCE--ECGKAFNWSSTLTKHKIIHTEEKP--YKCEKC 466
Cdd:COG5048   345 LHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPC 424

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 2217324070 467 GKAFKQSSILTNHKRIHTGEKPYKCEECGKSFNRSSTFTKHKV 509
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
137-524 5.26e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 5.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 137 SSTLTNHRKIYTEEKPYKCEEYNKSPKQLSTLTTHEIIHAGEKLYKC--EECGEAFNRSSNLTTHKIIHTGEKPYKCE-E 213
Cdd:COG5048    18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 214 CGKAFIWSSTLTEHKKIHTRKKPYKCEECGKAFIWSSTLTRHKRMHTGEKPYKCEECGKAFSQSST-------------- 279
Cdd:COG5048    98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQsnslhpplpansls 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 280 --------LTTHKIIHTGEKRYKCLECGKAFKQLSTLTTHKIIHVGEKLYKCEECG----KGFNRSSNLTTHKIIHTGEK 347
Cdd:COG5048   178 kdpssnlsLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSqlspKSLLSQSPSSLSSSDSSSSA 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 348 PYKCEECG--KAFIWSSTLTKHKRIHTR-EKPYKCEECGKAFIWSSTLTRHKRM--HTGE--KPYKCEE--CGKSFSQSS 418
Cdd:COG5048   258 SESPRSSLptASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRND 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 419 TLTTHKIIHTGEKPYKCEEC-------GKAFNWSSTLTKHKIIHTEEKPYKCE--KCGKAFKQSSILTNHKRIHTGEKP- 488
Cdd:COG5048   338 ALKRHILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPy 417

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 2217324070 489 -YKCEECGKSFNRSSTFTKHKVIHTGVKPYKCEECGK 524
Cdd:COG5048   418 nCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
234-565 1.66e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 234 KKPYKCEECGKAFIWSSTLTRHKRMHTGEKPYKC--EECGKAFSQSSTLTTHKIIHTGEKRYkcLECGKAFKQLSTLTTH 311
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 312 KIIHVGEKLYKCE-ECGKGFNRSSNLTTHKIIHTGEKPYKCEECGKAFIWSSTLTKHKRIHTREKPykcEECGKAFIWSS 390
Cdd:COG5048   109 SLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 391 TLTRHKRMHTGEKPYKCEECGKSFSQSSTLTTHKIIHTgEKPYKCEECGKAFN-----WSSTLTKHKIIHTEEKP-YKCE 464
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPksllsQSPSSLSSSDSSSSASEsPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 465 KCGKAFKQSSILTNHKRIHTG-EKPYKCEECGKSFNRSSTFTKHK--VIHTG--VKPYKCEE--CGKAFFWSSTLTKHKR 537
Cdd:COG5048   265 LPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGesLKPFSCPYslCGKLFSRNDALKRHIL 344

                         330       340       350
                  ....*....|....*....|....*....|....
gi 2217324070 538 IHTGEQPYKW------EKFGKAFNRSSHLTTDKI 565
Cdd:COG5048   345 LHTSISPAKEkllnssSKFSPLLNNEPPQSLQQY 378
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
207-559 3.34e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.24  E-value: 3.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 207 KPYKCEECGKAFIWSSTLTEHKKIHTRKKPYKC--EECGKAFIWSSTLTRHKRMHTGEKPYkcEECGKAFSQSSTLTTHK 284
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 285 IIHTGEKR-YKCLECGKAFKQLSTLTTHKIIHVGEKLYKCEECGKGFNRSSNLTTHKIIHTGEKPykcEECGKAFIWSST 363
Cdd:COG5048   110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 364 LTKHKRIHTREKPYKCEECGKAFIWSSTLTRHKRMHTgEKPYKCEECGKSFSQSSTLTTHKIIHTGEKPYKCEECGKAFN 443
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 444 WSSTLTKHKIIHTEE-------KPYKCEKCGKAFKQSSILTNHKR--IHTGE--KPYKCEE--CGKSFNRSSTFTKHKVI 510
Cdd:COG5048   266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2217324070 511 HTGVKPYKCeecgkafFWSSTLTKHKRIHTGE-----QPYKWEKFGKAFNRSSH 559
Cdd:COG5048   346 HTSISPAKE-------KLLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLSN 392
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 360-480 6.40e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 48.95  E-value: 6.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 360 WSSTLTKHKRIHTREKPYKCEECGKAFIWSSTL---TRHKRMHT-GEKPYKCE--ECGKSFSQSSTLTTHKiihtgekpy 433
Cdd:COG5189   301 IRGGISTGEMIDVRKLPCTNSSSNGKLAHGGERnidTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHM--------- 371

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2217324070 434 KCEECGKAFNWSSTLTKHKIIHTEEKPYKCEKCGKAFKQSSILTNHK 480
Cdd:COG5189   372 LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
392-416 1.47e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.47e-04
                          10        20
                  ....*....|....*....|....*
gi 2217324070 392 LTRHKRMHTGEKPYKCEECGKSFSQ 416
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
252-276 1.70e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.70e-04
                          10        20
                  ....*....|....*....|....*
gi 2217324070 252 LTRHKRMHTGEKPYKCEECGKAFSQ 276
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
476-500 5.46e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 5.46e-04
                          10        20
                  ....*....|....*....|....*
gi 2217324070 476 LTNHKRIHTGEKPYKCEECGKSFNR 500
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 220-340 1.01e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217324070 220 WSSTLTEHKKIHTRKKPYKCEECGKAFIWSSTL---TRHKRMHT-GEKPYKCE--ECGKAFSQSSTLTTHKIiHTgekry 293
Cdd:COG5189   301 IRGGISTGEMIDVRKLPCTNSSSNGKLAHGGERnidTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHML-HG----- 374

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2217324070 294 kclECGKAFKQLSTLTTHKIIHVGEKLYKCEECGKGFNRSSNLTTHK 340
Cdd:COG5189   375 ---HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
195-218 2.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 2.45e-03
                          10        20
                  ....*....|....*....|....
gi 2217324070 195 NLTTHKIIHTGEKPYKCEECGKAF 218
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
335-358 2.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 2.45e-03
                          10        20
                  ....*....|....*....|....
gi 2217324070 335 NLTTHKIIHTGEKPYKCEECGKAF 358
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
364-386 4.56e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.56e-03
                          10        20
                  ....*....|....*....|...
gi 2217324070 364 LTKHKRIHTREKPYKCEECGKAF 386
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
420-443 4.83e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.83e-03
                          10        20
                  ....*....|....*....|....
gi 2217324070 420 LTTHKIIHTGEKPYKCEECGKAFN 443
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
448-472 6.49e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 6.49e-03
                          10        20
                  ....*....|....*....|....*
gi 2217324070 448 LTKHKIIHTEEKPYKCEKCGKAFKQ 472
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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