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Conserved domains on  [gi|2462585354|ref|XP_054181836|]
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smoothelin isoform X9 [Homo sapiens]

Protein Classification

Smoothelin domain-containing protein( domain architecture ID 10575943)

Smoothelin domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 655-704 5.50e-18

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


:

Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 78.12  E-value: 5.50e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462585354 655 KAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRK 704
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAIRELRKRK 50
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 127-176 7.95e-14

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


:

Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 66.57  E-value: 7.95e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462585354 127 AEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQE 176
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAIRELRKRK 50
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 46-88 2.15e-09

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


:

Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 53.86  E-value: 2.15e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2462585354  46 EPTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAI 88
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAI 43
 
Name Accession Description Interval E-value
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 655-704 5.50e-18

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 78.12  E-value: 5.50e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462585354 655 KAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRK 704
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAIRELRKRK 50
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 127-176 7.95e-14

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 66.57  E-value: 7.95e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462585354 127 AEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQE 176
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAIRELRKRK 50
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 46-88 2.15e-09

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 53.86  E-value: 2.15e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2462585354  46 EPTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAI 88
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAI 43
 
Name Accession Description Interval E-value
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 655-704 5.50e-18

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 78.12  E-value: 5.50e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462585354 655 KAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRK 704
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAIRELRKRK 50
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 127-176 7.95e-14

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 66.57  E-value: 7.95e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462585354 127 AEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQE 176
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAIRELRKRK 50
Smoothelin pfam12510
Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is ...
 46-88 2.15e-09

Smoothelin cytoskeleton protein; This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.


Pssm-ID: 463614 [Multi-domain]  Cd Length: 50  Bit Score: 53.86  E-value: 2.15e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2462585354  46 EPTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAI 88
Cdd:pfam12510   1 EETSAASKLTAEELEAIEDEEVLDKLLETATDYEERRLIRAAI 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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