|
Name |
Accession |
Description |
Interval |
E-value |
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
921-1061 |
9.43e-33 |
|
Clathrin heavy chain repeat homology; :
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 124.31 E-value: 9.43e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 921 LSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSvfsEHRNLQNLLILTAIKADRTRVMEYISR-LDNYDALDIAS 999
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNS---ENPALQTKLIELYAKYDPQKEIERLDNkSNHYDIEKVGK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1000 IAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKD 1061
Cdd:smart00299 78 LCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKALLDKP 139
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
628-766 |
2.09e-32 |
|
Clathrin heavy chain repeat homology; :
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 123.15 E-value: 2.09e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 628 ASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNF-SQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLK 706
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLnSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462585569 707 EAKLTDQLPLIIVCDRFgFVHDLVLYLYR-NNLQRYIEIYVQKVNPSRTPAVIGGLLDVDC 766
Cdd:smart00299 81 KAKLYEEAVELYKKDGN-FKDAIVTLIEHlGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1070-1209 |
1.94e-29 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain. :
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 114.66 E-value: 1.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1070 YIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRE--SYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRC 1147
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRenPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLC 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1148 YEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFR 1209
Cdd:pfam00637 81 EKADLYEEAVILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
483-616 |
1.00e-28 |
|
Clathrin heavy chain repeat homology; :
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 112.75 E-value: 1.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 483 EPLANISQIVDIFMENSLIQQCTSFLLDALKNNrPAEGLLQTWLLEMNLVHAPQVADAILGNkMFTHYDRAHIAQLCEKA 562
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN-SENPALQTKLIELYAKYDPQKEIERLDN-KSNHYDIEKVGKLCEKA 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462585569 563 GLLQQALEHYTDLYDIKRAVVHT--HLLNPEWLVNFFGS-LSVEDSVECLHAMLSAN 616
Cdd:smart00299 83 KLYEEAVELYKKDGNFKDAIVTLieHLGNYEKAIEYFVKqNNPELWAEVLKALLDKP 139
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1216-1358 |
1.80e-28 |
|
Clathrin heavy chain repeat homology; :
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 111.98 E-value: 1.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1216 LHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGVFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAE 1295
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462585569 1296 QAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAwkeGQFKDIITKVANVELCYRALQFYLDYKP 1358
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIEHLGNY---EKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
775-902 |
2.90e-27 |
|
Clathrin heavy chain repeat homology; :
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 108.52 E-value: 2.90e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 775 IMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSP--ECFLRENAYYDSSVVGRYCE 852
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKeiERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 853 KRDPH-LACVAYERGQCDLELIKVCNENS-LFKSEARYLVCRKDPELWAHVL 902
Cdd:smart00299 81 KAKLYeEAVELYKKDGNFKDAIVTLIEHLgNYEKAIEYFVKQNNPELWAEVL 132
|
|
| Clathrin_H_link |
pfam13838 |
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ... |
298-363 |
9.67e-20 |
|
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268. :
Pssm-ID: 463995 Cd Length: 66 Bit Score: 84.18 E-value: 9.67e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462585569 298 NLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGIL 363
Cdd:pfam13838 1 GLPGADDLYFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
|
|
| Clathrin-link |
pfam09268 |
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of ... |
273-296 |
5.88e-08 |
|
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of alpha-alpha superhelix. They are predominantly found in clathrin, where they act as a heavy-chain linker domain. :
Pssm-ID: 462732 Cd Length: 24 Bit Score: 49.75 E-value: 5.88e-08
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
198-234 |
8.53e-06 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller. :
Pssm-ID: 460192 Cd Length: 37 Bit Score: 43.94 E-value: 8.53e-06
10 20 30
....*....|....*....|....*....|....*..
gi 2462585569 198 AAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVG 234
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
19-55 |
7.67e-04 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller. :
Pssm-ID: 460192 Cd Length: 37 Bit Score: 38.17 E-value: 7.67e-04
10 20 30
....*....|....*....|....*....|....*..
gi 2462585569 19 GINPANIGFSTLTMESDKFICIREKVGeQAQVTIIDM 55
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTK-KGQVQIVDV 36
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
921-1061 |
9.43e-33 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 124.31 E-value: 9.43e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 921 LSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSvfsEHRNLQNLLILTAIKADRTRVMEYISR-LDNYDALDIAS 999
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNS---ENPALQTKLIELYAKYDPQKEIERLDNkSNHYDIEKVGK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1000 IAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKD 1061
Cdd:smart00299 78 LCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKALLDKP 139
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
628-766 |
2.09e-32 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 123.15 E-value: 2.09e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 628 ASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNF-SQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLK 706
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLnSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462585569 707 EAKLTDQLPLIIVCDRFgFVHDLVLYLYR-NNLQRYIEIYVQKVNPSRTPAVIGGLLDVDC 766
Cdd:smart00299 81 KAKLYEEAVELYKKDGN-FKDAIVTLIEHlGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
921-1061 |
4.12e-30 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 116.59 E-value: 4.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 921 LSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSvfSEHRNLQNLLILTAIKADR-TRVMEYISRLDNYDALDIAS 999
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDS--RENPALQTALIELYAKYDDpEELEEFLKKNNNYDLEKVAK 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1000 IAVSSALYEEAFTVFHKFDMNASAIqVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKD 1061
Cdd:pfam00637 79 LCEKADLYEEAVILYKKIGNWKEAI-SLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNG 139
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1070-1209 |
1.94e-29 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 114.66 E-value: 1.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1070 YIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRE--SYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRC 1147
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRenPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLC 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1148 YEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFR 1209
Cdd:pfam00637 81 EKADLYEEAVILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1070-1207 |
2.44e-29 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 114.29 E-value: 2.44e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1070 YIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRE-SYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCY 1148
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSEnPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1149 EEGMYEAAKLLYSNVSNFARLASTLV-HLGEYQAAVDNSRKASSTRTWKEVCFACMDGQE 1207
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIeHLGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
483-616 |
1.00e-28 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 112.75 E-value: 1.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 483 EPLANISQIVDIFMENSLIQQCTSFLLDALKNNrPAEGLLQTWLLEMNLVHAPQVADAILGNkMFTHYDRAHIAQLCEKA 562
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN-SENPALQTKLIELYAKYDPQKEIERLDN-KSNHYDIEKVGKLCEKA 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462585569 563 GLLQQALEHYTDLYDIKRAVVHT--HLLNPEWLVNFFGS-LSVEDSVECLHAMLSAN 616
Cdd:smart00299 83 KLYEEAVELYKKDGNFKDAIVTLieHLGNYEKAIEYFVKqNNPELWAEVLKALLDKP 139
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1216-1358 |
1.80e-28 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 111.98 E-value: 1.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1216 LHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGVFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAE 1295
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462585569 1296 QAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAwkeGQFKDIITKVANVELCYRALQFYLDYKP 1358
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIEHLGNY---EKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
775-902 |
2.90e-27 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 108.52 E-value: 2.90e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 775 IMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSP--ECFLRENAYYDSSVVGRYCE 852
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKeiERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 853 KRDPH-LACVAYERGQCDLELIKVCNENS-LFKSEARYLVCRKDPELWAHVL 902
Cdd:smart00299 81 KAKLYeEAVELYKKDGNFKDAIVTLIEHLgNYEKAIEYFVKQNNPELWAEVL 132
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
630-768 |
4.49e-25 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 102.33 E-value: 4.49e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 630 KYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFS--QDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKE 707
Cdd:pfam00637 3 ESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDsrENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 708 AKLTDQLPLIIVCdrFGFVHDLV-LYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSE 768
Cdd:pfam00637 83 ADLYEEAVILYKK--IGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
785-912 |
1.37e-24 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 100.79 E-value: 1.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 785 DELVAEVEKRNRLKLLLPWLESQIQEG-CEEPATHNALAKIYIDSN--NSPECFLRENAYYDSSVVGRYCEKRDPH-LAC 860
Cdd:pfam00637 11 SRVVKLFEKAGLLEELISYLESALKEDsRENPALQTALIELYAKYDdpEELEEFLKKNNNYDLEKVAKLCEKADLYeEAV 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 861 VAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVLEETNPSRRQL 912
Cdd:pfam00637 91 ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
483-620 |
4.69e-23 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 96.56 E-value: 4.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 483 EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAP-QVADAILgnKMFTHYDRAHIAQLCEK 561
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRENPALQTALIELYAKYDDpEELEEFL--KKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 562 AGLLQQALEHYTDLYDIKRAV-VHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQN 620
Cdd:pfam00637 83 ADLYEEAVILYKKIGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin_H_link |
pfam13838 |
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ... |
298-363 |
9.67e-20 |
|
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.
Pssm-ID: 463995 Cd Length: 66 Bit Score: 84.18 E-value: 9.67e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462585569 298 NLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGIL 363
Cdd:pfam13838 1 GLPGADDLYFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1216-1358 |
2.20e-19 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 85.77 E-value: 2.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1216 LHIVIHADELEELMCYYQDRGYFEELILL-LEAALGLERAHMGVFTELAILYSKF-KPQKMLEHLELFWSrVNIPKVLRA 1293
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYlESALKEDSRENPALQTALIELYAKYdDPEELEEFLKKNNN-YDLEKVAKL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462585569 1294 AEQAHLWAELVFLYDKYEEYDNAVltMMSHPTEAWKEGQfkDIITKVANVELCYRALQFYLDYKP 1358
Cdd:pfam00637 80 CEKADLYEEAVILYKKIGNWKEAI--SLLKKLGDYKDAI--EYAVKSSNPELWEELLEALLDNGR 140
|
|
| Clathrin-link |
pfam09268 |
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of ... |
273-296 |
5.88e-08 |
|
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of alpha-alpha superhelix. They are predominantly found in clathrin, where they act as a heavy-chain linker domain.
Pssm-ID: 462732 Cd Length: 24 Bit Score: 49.75 E-value: 5.88e-08
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
198-234 |
8.53e-06 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 43.94 E-value: 8.53e-06
10 20 30
....*....|....*....|....*....|....*..
gi 2462585569 198 AAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVG 234
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Coatomer_WDAD_beta-like |
cd22947 |
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', ... |
1006-1107 |
5.29e-05 |
|
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', also called beta'-coat protein; beta'-COP; p102, is a component of the coatomer, which is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complexes are hetero-oligomers composed of at least an alpha, beta, beta', gamma, delta, epsilon and zeta subunit. It is a heptameric complex that can polymerize into a cage to deform the membrane into a bud. This model corresponds to the WD-associated (WDAD) region found in coatomer subunits beta and beta' and is composed of a beta-propeller and an alpha-solenoid. The WD40 domain is found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. It typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40. Between the GH and WD lies a conserved core. It forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet. Each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade. The last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure. The residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands allowing them to bind either stably or reversibly.
Pssm-ID: 438572 Cd Length: 475 Bit Score: 47.46 E-value: 5.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1006 LYEEAFTVF----HKFDMnasAIQvliehIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLE 1081
Cdd:cd22947 327 LKELALEVStdpdHKFEL---ALQ-----LGDLDLALEIARESESESKWKQLGDLALSKGDFDLAEECLKKAGDLSGLLL 398
|
90 100
....*....|....*....|....*.
gi 2462585569 1082 VvqsASRSNNWEDLVKFLQMARKKGR 1107
Cdd:cd22947 399 L---YSSTGDKEGLEELAELAEAAGK 421
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
19-55 |
7.67e-04 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 38.17 E-value: 7.67e-04
10 20 30
....*....|....*....|....*....|....*..
gi 2462585569 19 GINPANIGFSTLTMESDKFICIREKVGeQAQVTIIDM 55
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTK-KGQVQIVDV 36
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1032-1189 |
3.84e-03 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 40.87 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1032 GNLDRAYEFAERC-----NEPAVWSQLAQAQLQKDLVKEAINSY-----IRGDDPSSYLEVVQSASRSNNWEDLVKFLQM 1101
Cdd:COG2956 56 GEYDRAIRIHQKLlerdpDRAEALLELAQDYLKAGLLDRAEELLeklleLDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1102 ARK-KGRESYIETELIFALAKTSR----VSELEDFING-PNNAHIQ-QVGDRCYEEGMYEAAKLLY--------SNVSNF 1166
Cdd:COG2956 136 LLKlGPENAHAYCELAELYLEQGDydeaIEALEKALKLdPDCARALlLLAELYLEQGDYEEAIAALeraleqdpDYLPAL 215
|
170 180
....*....|....*....|...
gi 2462585569 1167 ARLASTLVHLGEYQAAVDNSRKA 1189
Cdd:COG2956 216 PRLAELYEKLGDPEEALELLRKA 238
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
921-1061 |
9.43e-33 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 124.31 E-value: 9.43e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 921 LSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSvfsEHRNLQNLLILTAIKADRTRVMEYISR-LDNYDALDIAS 999
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNS---ENPALQTKLIELYAKYDPQKEIERLDNkSNHYDIEKVGK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1000 IAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKD 1061
Cdd:smart00299 78 LCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKALLDKP 139
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
628-766 |
2.09e-32 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 123.15 E-value: 2.09e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 628 ASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNF-SQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLK 706
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLnSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462585569 707 EAKLTDQLPLIIVCDRFgFVHDLVLYLYR-NNLQRYIEIYVQKVNPSRTPAVIGGLLDVDC 766
Cdd:smart00299 81 KAKLYEEAVELYKKDGN-FKDAIVTLIEHlGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
921-1061 |
4.12e-30 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 116.59 E-value: 4.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 921 LSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSvfSEHRNLQNLLILTAIKADR-TRVMEYISRLDNYDALDIAS 999
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDS--RENPALQTALIELYAKYDDpEELEEFLKKNNNYDLEKVAK 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1000 IAVSSALYEEAFTVFHKFDMNASAIqVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKD 1061
Cdd:pfam00637 79 LCEKADLYEEAVILYKKIGNWKEAI-SLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNG 139
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1070-1209 |
1.94e-29 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 114.66 E-value: 1.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1070 YIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRE--SYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRC 1147
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRenPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLC 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 1148 YEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFR 1209
Cdd:pfam00637 81 EKADLYEEAVILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1070-1207 |
2.44e-29 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 114.29 E-value: 2.44e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1070 YIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRE-SYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCY 1148
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSEnPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1149 EEGMYEAAKLLYSNVSNFARLASTLV-HLGEYQAAVDNSRKASSTRTWKEVCFACMDGQE 1207
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIeHLGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
483-616 |
1.00e-28 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 112.75 E-value: 1.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 483 EPLANISQIVDIFMENSLIQQCTSFLLDALKNNrPAEGLLQTWLLEMNLVHAPQVADAILGNkMFTHYDRAHIAQLCEKA 562
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN-SENPALQTKLIELYAKYDPQKEIERLDN-KSNHYDIEKVGKLCEKA 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462585569 563 GLLQQALEHYTDLYDIKRAVVHT--HLLNPEWLVNFFGS-LSVEDSVECLHAMLSAN 616
Cdd:smart00299 83 KLYEEAVELYKKDGNFKDAIVTLieHLGNYEKAIEYFVKqNNPELWAEVLKALLDKP 139
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1216-1358 |
1.80e-28 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 111.98 E-value: 1.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1216 LHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGVFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAE 1295
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462585569 1296 QAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAwkeGQFKDIITKVANVELCYRALQFYLDYKP 1358
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIEHLGNY---EKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
775-902 |
2.90e-27 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 108.52 E-value: 2.90e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 775 IMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSP--ECFLRENAYYDSSVVGRYCE 852
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKeiERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 853 KRDPH-LACVAYERGQCDLELIKVCNENS-LFKSEARYLVCRKDPELWAHVL 902
Cdd:smart00299 81 KAKLYeEAVELYKKDGNFKDAIVTLIEHLgNYEKAIEYFVKQNNPELWAEVL 132
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
630-768 |
4.49e-25 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 102.33 E-value: 4.49e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 630 KYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFS--QDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKE 707
Cdd:pfam00637 3 ESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDsrENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 708 AKLTDQLPLIIVCdrFGFVHDLV-LYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSE 768
Cdd:pfam00637 83 ADLYEEAVILYKK--IGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
785-912 |
1.37e-24 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 100.79 E-value: 1.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 785 DELVAEVEKRNRLKLLLPWLESQIQEG-CEEPATHNALAKIYIDSN--NSPECFLRENAYYDSSVVGRYCEKRDPH-LAC 860
Cdd:pfam00637 11 SRVVKLFEKAGLLEELISYLESALKEDsRENPALQTALIELYAKYDdpEELEEFLKKNNNYDLEKVAKLCEKADLYeEAV 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462585569 861 VAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVLEETNPSRRQL 912
Cdd:pfam00637 91 ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
483-620 |
4.69e-23 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 96.56 E-value: 4.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 483 EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAP-QVADAILgnKMFTHYDRAHIAQLCEK 561
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRENPALQTALIELYAKYDDpEELEEFL--KKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 562 AGLLQQALEHYTDLYDIKRAV-VHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQN 620
Cdd:pfam00637 83 ADLYEEAVILYKKIGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin_H_link |
pfam13838 |
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ... |
298-363 |
9.67e-20 |
|
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.
Pssm-ID: 463995 Cd Length: 66 Bit Score: 84.18 E-value: 9.67e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462585569 298 NLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGIL 363
Cdd:pfam13838 1 GLPGADDLYFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1216-1358 |
2.20e-19 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 85.77 E-value: 2.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1216 LHIVIHADELEELMCYYQDRGYFEELILL-LEAALGLERAHMGVFTELAILYSKF-KPQKMLEHLELFWSrVNIPKVLRA 1293
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYlESALKEDSRENPALQTALIELYAKYdDPEELEEFLKKNNN-YDLEKVAKL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462585569 1294 AEQAHLWAELVFLYDKYEEYDNAVltMMSHPTEAWKEGQfkDIITKVANVELCYRALQFYLDYKP 1358
Cdd:pfam00637 80 CEKADLYEEAVILYKKIGNWKEAI--SLLKKLGDYKDAI--EYAVKSSNPELWEELLEALLDNGR 140
|
|
| Clathrin-link |
pfam09268 |
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of ... |
273-296 |
5.88e-08 |
|
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of alpha-alpha superhelix. They are predominantly found in clathrin, where they act as a heavy-chain linker domain.
Pssm-ID: 462732 Cd Length: 24 Bit Score: 49.75 E-value: 5.88e-08
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
198-234 |
8.53e-06 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 43.94 E-value: 8.53e-06
10 20 30
....*....|....*....|....*....|....*..
gi 2462585569 198 AAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVG 234
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Coatomer_WDAD |
pfam04053 |
Coatomer WD associated region; This region is composed of WD40 repeats. |
1015-1109 |
4.51e-05 |
|
Coatomer WD associated region; This region is composed of WD40 repeats.
Pssm-ID: 427679 Cd Length: 439 Bit Score: 47.61 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1015 HKFDMnasAIQvliehIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPS--SYLevvqsASRSNNW 1092
Cdd:pfam04053 319 TRFDL---ALE-----LGNLDVALEIAKELDDPAKWKRLGDAALSQGNIKLAEEAYQKAKDFDklLLL-----YLSTGNM 385
|
90
....*....|....*..
gi 2462585569 1093 EDLVKFLQMARKKGRES 1109
Cdd:pfam04053 386 EKLKKLAKIAEKRGDYN 402
|
|
| Coatomer_WDAD_beta-like |
cd22947 |
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', ... |
1006-1107 |
5.29e-05 |
|
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', also called beta'-coat protein; beta'-COP; p102, is a component of the coatomer, which is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complexes are hetero-oligomers composed of at least an alpha, beta, beta', gamma, delta, epsilon and zeta subunit. It is a heptameric complex that can polymerize into a cage to deform the membrane into a bud. This model corresponds to the WD-associated (WDAD) region found in coatomer subunits beta and beta' and is composed of a beta-propeller and an alpha-solenoid. The WD40 domain is found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. It typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40. Between the GH and WD lies a conserved core. It forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet. Each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade. The last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure. The residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands allowing them to bind either stably or reversibly.
Pssm-ID: 438572 Cd Length: 475 Bit Score: 47.46 E-value: 5.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1006 LYEEAFTVF----HKFDMnasAIQvliehIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLE 1081
Cdd:cd22947 327 LKELALEVStdpdHKFEL---ALQ-----LGDLDLALEIARESESESKWKQLGDLALSKGDFDLAEECLKKAGDLSGLLL 398
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90 100
....*....|....*....|....*.
gi 2462585569 1082 VvqsASRSNNWEDLVKFLQMARKKGR 1107
Cdd:cd22947 399 L---YSSTGDKEGLEELAELAEAAGK 421
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| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
19-55 |
7.67e-04 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 38.17 E-value: 7.67e-04
10 20 30
....*....|....*....|....*....|....*..
gi 2462585569 19 GINPANIGFSTLTMESDKFICIREKVGeQAQVTIIDM 55
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTK-KGQVQIVDV 36
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| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1032-1189 |
3.84e-03 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 40.87 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1032 GNLDRAYEFAERC-----NEPAVWSQLAQAQLQKDLVKEAINSY-----IRGDDPSSYLEVVQSASRSNNWEDLVKFLQM 1101
Cdd:COG2956 56 GEYDRAIRIHQKLlerdpDRAEALLELAQDYLKAGLLDRAEELLeklleLDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462585569 1102 ARK-KGRESYIETELIFALAKTSR----VSELEDFING-PNNAHIQ-QVGDRCYEEGMYEAAKLLY--------SNVSNF 1166
Cdd:COG2956 136 LLKlGPENAHAYCELAELYLEQGDydeaIEALEKALKLdPDCARALlLLAELYLEQGDYEEAIAALeraleqdpDYLPAL 215
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170 180
....*....|....*....|...
gi 2462585569 1167 ARLASTLVHLGEYQAAVDNSRKA 1189
Cdd:COG2956 216 PRLAELYEKLGDPEEALELLRKA 238
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