|
Name |
Accession |
Description |
Interval |
E-value |
| PUFD_like_1 |
cd14260 |
PCGF Ub-like fold discriminator of BCOR-like 1; The PUFD domain binds the RAWUL (RING finger ... |
1438-1551 |
2.06e-67 |
|
PCGF Ub-like fold discriminator of BCOR-like 1; The PUFD domain binds the RAWUL (RING finger and WD40-associated ubiquitin-like) domain of the polycomb-group RING finger homologs PCGF1 and PCGF3. PUFD was characterized as a domain of the BCL6 corepressor BCOR. It does not appear to bind to PCGF2 and PCGF4. PCGF1 is a component of the Polycomb group (PcG) multi-protein BCOR complex, which is involved in repressing the transcription of BCL6 and CDKN1A. The BCL-6 corepressor-like protein 1 (BCoR-L1) is largely uncharacterized; it contains ankyrin repeats.
Pssm-ID: 271223 Cd Length: 115 Bit Score: 222.42 E-value: 2.06e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1438 EEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAER 1517
Cdd:cd14260 2 EEDDFMFEFSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEIATMPKAEFYRQVLSSQLLTPAER 81
|
90 100 110
....*....|....*....|....*....|....
gi 2462630480 1518 PGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVE 1551
Cdd:cd14260 82 PGGLDDRSPQGSSETVELVRYEPELLRLLGSAVE 115
|
|
| PUFD |
pfam16553 |
BCORL-PCGF1-binding domain; PUFD is the minimal domain at the C-terminus of BCORL (BCL6 ... |
1439-1553 |
9.04e-61 |
|
BCORL-PCGF1-binding domain; PUFD is the minimal domain at the C-terminus of BCORL (BCL6 corepressor) that is needed for binding and giving specificity to some of the PCGF proteins, polycomb-group RING finger homologs. PUFD binds to the RAWUL (RING finger- and WD40-associated ubiquitin-like) domain of the particular PCGF PCGF1, pfam16207. Polycomb group proteins form repressive complexes (PRC) that mediate epigenetic modifications of histones. In humans there are many different PCGF homologs whose functions all vary, but the direct binding partner of PCGF1 is BCOR. BCOR has emerged as an important player in development and health.
Pssm-ID: 465171 Cd Length: 114 Bit Score: 203.38 E-value: 9.04e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1439 EDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERP 1518
Cdd:pfam16553 1 SDVFEFEFSDKPLLPCYNIQVSLSQGPRNWLLLSDVLKRLKMSSRIFRARFPHFEVVTIAEAEFYKQVSLSQLLSPPEDL 80
|
90 100 110
....*....|....*....|....*....|....*
gi 2462630480 1519 GGlddrSPPGSSETVELVRYEPDLLRLLGSEVEFQ 1553
Cdd:pfam16553 81 EA----FNPDSKELVELVEFTPELQTLLGSSVEFL 111
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1266-1375 |
1.33e-27 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 114.67 E-value: 1.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1266 NAGETLLQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVN 1345
Cdd:COG0666 118 KDGETPLHLAAYNGNLEIVKLLLEAGA-DVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAEN 196
|
90 100 110
....*....|....*....|....*....|
gi 2462630480 1346 DNLETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:COG0666 197 GHLEIVKLLLEAGADVNAKDNDGKTALDLA 226
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
1272-1363 |
1.59e-16 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 76.31 E-value: 1.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1272 LQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHgANVNCSAQDGTrPVHDAVVNDNLETI 1351
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGA-DANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNGRT-ALHYAARSGHLEIV 77
|
90
....*....|..
gi 2462630480 1352 WLLLSYGADPTL 1363
Cdd:pfam12796 78 KLLLEKGADINV 89
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
100-538 |
1.38e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 83.06 E-value: 1.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 100 PLPAPIcPPAPGSASVPHSvPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPAL-------------APAPPS 166
Cdd:PHA03247 2571 PRPAPR-PSEPAVTSRARR-PDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPspspaanepdphpPPTVPP 2648
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 167 VPTLISDSNPLSVS-----ASVLVPVPASAPPSGPVPLSAPAP-APLSVPVSAPPlaliQAPVPPSAPTLVLAPVPTPvl 240
Cdd:PHA03247 2649 PERPRDDPAPGRVSrprraRRLGRAAQASSPPQRPRRRAARPTvGSLTSLADPPP----PPPTPEPAPHALVSATPLP-- 2722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 241 apmpastPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAiPTSAPIPASFSLS 320
Cdd:PHA03247 2723 -------PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR-RLTRPAVASLSES 2794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 321 RVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLP--GVLAS 398
Cdd:PHA03247 2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPsrSPAAK 2874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 399 PELRSYPYAFSVARPLTSDSKlvslevnrLPCTSPSGSTTTQPAPDGVPGPLAdtslvTASAKVLPTPQPLLPAPSGSSA 478
Cdd:PHA03247 2875 PAAPARPPVRRLARPAVSRST--------ESFALPPDQPERPPQPQAPPPPQP-----QPQPPPPPQPQPPPPPPPRPQP 2941
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462630480 479 PPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLE--REMASPPECSeMPLDLSSKSNRQKLPLP 538
Cdd:PHA03247 2942 PLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvpRFRVPQPAPS-REAPASSTPPLTGHSLS 3002
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
1269-1360 |
3.63e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 63.92 E-value: 3.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1269 ETLLQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNL 1348
Cdd:PHA03100 160 KLLIDKGVDINAKNRVNYLLSYGV-PINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNK 238
|
90
....*....|..
gi 2462630480 1349 ETIWLLLSYGAD 1360
Cdd:PHA03100 239 EIFKLLLNNGPS 250
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
120-566 |
1.78e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 52.85 E-value: 1.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 120 PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAP-PSGPVP 198
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPsPHPPLQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 199 LSAPAPAPLSVPVSAPPLALIQAPVPP------SAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPStp 272
Cdd:pfam03154 251 PMTQPPPPSQVSPQPLPQPSLHGQMPPmphslqTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTP-- 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 273 tliPAFAPTPVPAPTPAPIFTPAPTPMPAATPaaiPTSAPIPAsfslsrvcFPAAQA---PAMQKVPLSFQPGTVLtpsq 349
Cdd:pfam03154 329 ---PSQSQLQSQQPPREQPLPPAPLSMPHIKP---PPTTPIPQ--------LPNPQShkhPPHLSGPSPFQMNSNL---- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 350 plvyiPPPSCGQPLSvaTLPTTLGVSStlTLPVLPSYLQDRCLPGVLASPelrsypyafsvarPLTSDSKLVSLEVNRLP 429
Cdd:pfam03154 391 -----PPPPALKPLS--SLSTHHPPSA--HPPPLQLMPQSQQLPPPPAQP-------------PVLTQSQSLPPPAASHP 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 430 CTSPSGSTTTQP-------APDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPphpakMPSGTEQQTEGTSVTFSP 502
Cdd:pfam03154 449 PTSGLHQVPSQSpfpqhpfVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSGP-----VPAAVSCPLPPVQIKEEA 523
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 503 LKSPPQLEremaSPPecsempldlssksnrqklPLPNQRKTPPMPVLTPVHTSSKALLSTVLSR 566
Cdd:pfam03154 524 LDEAEEPE----SPP------------------PPPRSPSPEPTVVNTPSHASQSARFYKHLDR 565
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
1302-1330 |
6.26e-06 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 44.12 E-value: 6.26e-06
10 20
....*....|....*....|....*....
gi 2462630480 1302 GYTALHEACSRGWTDILNILLEHGANVNC 1330
Cdd:smart00248 2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
1261-1360 |
9.72e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 43.85 E-value: 9.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1261 LIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHG---ANVNCSAQ--DG 1335
Cdd:cd22192 10 LLQQKRISESPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelVNEPMTSDlyQG 89
|
90 100
....*....|....*....|....*
gi 2462630480 1336 TRPVHDAVVNDNLETIWLLLSYGAD 1360
Cdd:cd22192 90 ETALHIAVVNQNLNLVRELIARGAD 114
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
174-239 |
9.88e-03 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 40.26 E-value: 9.88e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462630480 174 SNPLSVSASVlvPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTlvlAPVPTPV 239
Cdd:TIGR00601 75 SKPKTGTGKV--APPAATPTSAPTPTPSPPASPASGMSAAPASAVEEKSPSEESAT---ATAPESP 135
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PUFD_like_1 |
cd14260 |
PCGF Ub-like fold discriminator of BCOR-like 1; The PUFD domain binds the RAWUL (RING finger ... |
1438-1551 |
2.06e-67 |
|
PCGF Ub-like fold discriminator of BCOR-like 1; The PUFD domain binds the RAWUL (RING finger and WD40-associated ubiquitin-like) domain of the polycomb-group RING finger homologs PCGF1 and PCGF3. PUFD was characterized as a domain of the BCL6 corepressor BCOR. It does not appear to bind to PCGF2 and PCGF4. PCGF1 is a component of the Polycomb group (PcG) multi-protein BCOR complex, which is involved in repressing the transcription of BCL6 and CDKN1A. The BCL-6 corepressor-like protein 1 (BCoR-L1) is largely uncharacterized; it contains ankyrin repeats.
Pssm-ID: 271223 Cd Length: 115 Bit Score: 222.42 E-value: 2.06e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1438 EEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAER 1517
Cdd:cd14260 2 EEDDFMFEFSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEIATMPKAEFYRQVLSSQLLTPAER 81
|
90 100 110
....*....|....*....|....*....|....
gi 2462630480 1518 PGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVE 1551
Cdd:cd14260 82 PGGLDDRSPQGSSETVELVRYEPELLRLLGSAVE 115
|
|
| PUFD |
pfam16553 |
BCORL-PCGF1-binding domain; PUFD is the minimal domain at the C-terminus of BCORL (BCL6 ... |
1439-1553 |
9.04e-61 |
|
BCORL-PCGF1-binding domain; PUFD is the minimal domain at the C-terminus of BCORL (BCL6 corepressor) that is needed for binding and giving specificity to some of the PCGF proteins, polycomb-group RING finger homologs. PUFD binds to the RAWUL (RING finger- and WD40-associated ubiquitin-like) domain of the particular PCGF PCGF1, pfam16207. Polycomb group proteins form repressive complexes (PRC) that mediate epigenetic modifications of histones. In humans there are many different PCGF homologs whose functions all vary, but the direct binding partner of PCGF1 is BCOR. BCOR has emerged as an important player in development and health.
Pssm-ID: 465171 Cd Length: 114 Bit Score: 203.38 E-value: 9.04e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1439 EDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERP 1518
Cdd:pfam16553 1 SDVFEFEFSDKPLLPCYNIQVSLSQGPRNWLLLSDVLKRLKMSSRIFRARFPHFEVVTIAEAEFYKQVSLSQLLSPPEDL 80
|
90 100 110
....*....|....*....|....*....|....*
gi 2462630480 1519 GGlddrSPPGSSETVELVRYEPDLLRLLGSEVEFQ 1553
Cdd:pfam16553 81 EA----FNPDSKELVELVEFTPELQTLLGSSVEFL 111
|
|
| PUFD_like |
cd14259 |
PCGF Ub-like fold discriminator and related domains; The PUFD domain binds the RAWUL (RING ... |
1440-1551 |
1.87e-42 |
|
PCGF Ub-like fold discriminator and related domains; The PUFD domain binds the RAWUL (RING finger and WD40-associated ubiquitin-like) domain of the polycomb-group RING finger homologs PCGF1 and PCGF3. PUFD was characterized as a domain of the BCL6 corepressor BCOR. It does not appear to bind to PCGF2 and PCGF4. PCGF1 is a component of the Polycomb group (PcG) multi-protein BCOR complex, which is involved in repressing the transcription of BCL6 and CDKN1A. The BCL-6 corepressor (BCOR) is a transcriptional repressor required for germinal center formation and is possibly involved in apoptosis.
Pssm-ID: 271222 Cd Length: 106 Bit Score: 150.54 E-value: 1.87e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1440 DDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPg 1519
Cdd:cd14259 1 DDFEFEFSDEPLPPLYNLRISPNDGPRNWHLLSDVLTRLKLKSRDFLLKQICLELTSIPIEDFLEQASCLQLLCAGEKL- 79
|
90 100 110
....*....|....*....|....*....|..
gi 2462630480 1520 glddrSPPGSSETVELVRYEPDLLRLLGSEVE 1551
Cdd:cd14259 80 -----TNNVSSSKVELVEYNDSLRSLLGIEVE 106
|
|
| PUFD |
cd14261 |
PCGF Ub-like fold discriminator of BCOR; The PUFD domain binds the RAWUL (RING finger and ... |
1440-1551 |
1.51e-36 |
|
PCGF Ub-like fold discriminator of BCOR; The PUFD domain binds the RAWUL (RING finger and WD40-associated ubiquitin-like) domain of the polycomb-group RING finger homologs PCGF1 and PCGF3. PUFD was characterized as a domain of the BCL6 corepressor BCOR. It does not appear to bind to PCGF2 and PCGF4. PCGF1 is a component of the Polycomb group (PcG) multi-protein BCOR complex, which is involved in repressing the transcription of BCL6 and CDKN1A. The BCL-6 corepressor (BCOR) is a transcriptional repressor required for germinal center formation and is possibly involved in apoptosis.
Pssm-ID: 271224 Cd Length: 117 Bit Score: 134.20 E-value: 1.51e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1440 DDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPG 1519
Cdd:cd14261 6 DVFEFEFSDRPLLPCYNIQVSLSQGPRNWLLLSDVLKRLKMSSRIFRCNFPNVEVVTIAEAEFYRQVSLSQLFSCPKDLE 85
|
90 100 110
....*....|....*....|....*....|..
gi 2462630480 1520 GLDdrspPGSSETVELVRYEPDLLRLLGSEVE 1551
Cdd:cd14261 86 AFN----PDSKELLDLVEFTNELQTLLGSSLE 113
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1266-1375 |
1.33e-27 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 114.67 E-value: 1.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1266 NAGETLLQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVN 1345
Cdd:COG0666 118 KDGETPLHLAAYNGNLEIVKLLLEAGA-DVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAEN 196
|
90 100 110
....*....|....*....|....*....|
gi 2462630480 1346 DNLETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:COG0666 197 GHLEIVKLLLEAGADVNAKDNDGKTALDLA 226
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1261-1377 |
2.74e-25 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 107.73 E-value: 2.74e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1261 LIVNKNAGETLLQRAARLGYKDVVLYCLQKDsEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVH 1340
Cdd:COG0666 80 INAKDDGGNTLLHAAARNGDLEIVKLLLEAG-ADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLH 158
|
90 100 110
....*....|....*....|....*....|....*..
gi 2462630480 1341 DAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASS 1377
Cdd:COG0666 159 LAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAE 195
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1256-1375 |
9.16e-20 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 91.55 E-value: 9.16e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1256 PEARRLIVNKNA--------GETLLQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHGAN 1327
Cdd:COG0666 133 LEIVKLLLEAGAdvnaqdndGNTPLHLAAANGNLEIVKLLLEAGA-DVNARDNDGETPLHLAAENGHLEIVKLLLEAGAD 211
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2462630480 1328 VNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:COG0666 212 VNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLA 259
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1261-1375 |
7.13e-17 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 83.08 E-value: 7.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1261 LIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVH 1340
Cdd:COG0666 46 ALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLH 125
|
90 100 110
....*....|....*....|....*....|....*
gi 2462630480 1341 DAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:COG0666 126 LAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA 160
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
1272-1363 |
1.59e-16 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 76.31 E-value: 1.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1272 LQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHgANVNCSAQDGTrPVHDAVVNDNLETI 1351
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGA-DANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNGRT-ALHYAARSGHLEIV 77
|
90
....*....|..
gi 2462630480 1352 WLLLSYGADPTL 1363
Cdd:pfam12796 78 KLLLEKGADINV 89
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
100-538 |
1.38e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 83.06 E-value: 1.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 100 PLPAPIcPPAPGSASVPHSvPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPAL-------------APAPPS 166
Cdd:PHA03247 2571 PRPAPR-PSEPAVTSRARR-PDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPspspaanepdphpPPTVPP 2648
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 167 VPTLISDSNPLSVS-----ASVLVPVPASAPPSGPVPLSAPAP-APLSVPVSAPPlaliQAPVPPSAPTLVLAPVPTPvl 240
Cdd:PHA03247 2649 PERPRDDPAPGRVSrprraRRLGRAAQASSPPQRPRRRAARPTvGSLTSLADPPP----PPPTPEPAPHALVSATPLP-- 2722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 241 apmpastPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAiPTSAPIPASFSLS 320
Cdd:PHA03247 2723 -------PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR-RLTRPAVASLSES 2794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 321 RVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLP--GVLAS 398
Cdd:PHA03247 2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPsrSPAAK 2874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 399 PELRSYPYAFSVARPLTSDSKlvslevnrLPCTSPSGSTTTQPAPDGVPGPLAdtslvTASAKVLPTPQPLLPAPSGSSA 478
Cdd:PHA03247 2875 PAAPARPPVRRLARPAVSRST--------ESFALPPDQPERPPQPQAPPPPQP-----QPQPPPPPQPQPPPPPPPRPQP 2941
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462630480 479 PPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLE--REMASPPECSeMPLDLSSKSNRQKLPLP 538
Cdd:PHA03247 2942 PLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvpRFRVPQPAPS-REAPASSTPPLTGHSLS 3002
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1266-1372 |
4.60e-12 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 68.44 E-value: 4.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1266 NAGETLLQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVN 1345
Cdd:COG0666 184 NDGETPLHLAAENGHLEIVKLLLEAGA-DVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAA 262
|
90 100
....*....|....*....|....*..
gi 2462630480 1346 DNLETIWLLLSYGADPTLATYSGQTAM 1372
Cdd:COG0666 263 GAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
1263-1329 |
2.97e-10 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 58.20 E-value: 2.97e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462630480 1263 VNKNAGETLLQRAARLGYKDVVLYCLQKdsEDVNHRDNaGYTALHEACSRGWTDILNILLEHGANVN 1329
Cdd:pfam12796 25 LQDKNGRTALHLAAKNGHLEIVKLLLEH--ADVNLKDN-GRTALHYAARSGHLEIVKLLLEKGADIN 88
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
1269-1360 |
3.63e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 63.92 E-value: 3.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1269 ETLLQRAARLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNL 1348
Cdd:PHA03100 160 KLLIDKGVDINAKNRVNYLLSYGV-PINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNK 238
|
90
....*....|..
gi 2462630480 1349 ETIWLLLSYGAD 1360
Cdd:PHA03100 239 EIFKLLLNNGPS 250
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
1306-1377 |
4.74e-09 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 54.74 E-value: 4.74e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462630480 1306 LHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGAdpTLATYSGQTAMKLASS 1377
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAAR 70
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
1256-1375 |
4.92e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 57.37 E-value: 4.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1256 PEARRLIVNKNA--------GETLLQRAA--RLGYKDVVLYCLQKDSeDVNHRDNAGYTALHEA--CSRGWTDILNILLE 1323
Cdd:PHA03100 86 KEIVKLLLEYGAnvnapdnnGITPLLYAIskKSNSYSIVEYLLDNGA-NVNIKNSDGENLLHLYleSNKIDLKILKLLID 164
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1324 HGANVNcsAQD------------------GTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:PHA03100 165 KGVDIN--AKNrvnyllsygvpinikdvyGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIA 232
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
107-337 |
2.21e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 55.65 E-value: 2.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 107 PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSvptlisdsnPLSVSASVLVP 186
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAL---------AAARQASARGP 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 187 VPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAptlvlAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSS 266
Cdd:PRK12323 445 GGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAP-----AAAPAPADDDPPPWEELPPEFASPAPAQPDAAPA 519
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462630480 267 GPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPL 337
Cdd:PRK12323 520 GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLPV 590
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
1257-1385 |
2.50e-07 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 54.19 E-value: 2.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1257 EARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGT 1336
Cdd:COG0666 9 LLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGN 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2462630480 1337 RPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASS----DTMKRFLS 1385
Cdd:COG0666 89 TLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYngnlEIVKLLLE 141
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
83-511 |
3.85e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.33 E-value: 3.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 83 TGVPVEGTLPLVTTNFSPLP-APICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPvqvatsvPAPSPPLAPVPALA 161
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPaAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP-------AAGPPRRLTRPAVA 2789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 162 PAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPlaliqAPVPPSAPTLVLAPVPTPVLA 241
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP-----GPPPPSLPLGGSVAPGGDVRR 2864
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 242 PMPASTPPAapappsvpmptptpssgppstptlipafaptpvpaptpapifTPAPTPMPAATPAAIPTSAPIPASFSLSR 321
Cdd:PHA03247 2865 RPPSRSPAA------------------------------------------KPAAPARPPVRRLARPAVSRSTESFALPP 2902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 322 VCFPAAQAPAMQKVPLSFQPgtvlTPSQPLVYIPPPSCGQPLSVATlPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPEL 401
Cdd:PHA03247 2903 DQPERPPQPQAPPPPQPQPQ----PPPPPQPQPPPPPPPRPQPPLA-PTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRF 2977
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 402 RSYPYAFSVARPLTSDSKLVSLEVNRL------------PCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV-LPTPQP 468
Cdd:PHA03247 2978 RVPQPAPSREAPASSTPPLTGHSLSRVsswasslalheeTDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSdLEALDP 3057
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2462630480 469 LLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLER 511
Cdd:PHA03247 3058 LPPEPHDPFAHEPDPATPEAGARESPSSQFGPPPLSANAALSR 3100
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
1302-1354 |
9.59e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 47.27 E-value: 9.59e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 1302 GYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETI-WLL 1354
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLkLLL 54
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
1294-1371 |
9.72e-07 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 53.10 E-value: 9.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1294 DVNHRDNAGYTALHeACSRGW---TDILNILLEHGANVNCSAQDGTRPVHDAVVNDN--LETIWLLLSYGADPTLATYSG 1368
Cdd:PHA03095 109 DVNAKDKVGRTPLH-VYLSGFninPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNanVELLRLLIDAGADVYAVDDRF 187
|
...
gi 2462630480 1369 QTA 1371
Cdd:PHA03095 188 RSL 190
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
1249-1360 |
1.05e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 53.53 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1249 PTARQIPPEARRLIVNKNA----GETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRG-WTDILNILLE 1323
Cdd:PHA02876 284 PSLSRLVPKLLERGADVNAknikGETPLYLMAKNGYDTENIRTLIMLGADVNAADRLYITPLHQASTLDrNKDIVITLLE 363
|
90 100 110
....*....|....*....|....*....|....*..
gi 2462630480 1324 HGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGAD 1360
Cdd:PHA02876 364 LGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGAD 400
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
99-321 |
1.09e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 53.34 E-value: 1.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 99 SPLPAPICPPAPgSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVpalapappsvptlisdsnPLS 178
Cdd:PRK12323 376 TAAAAPVAQPAP-AAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAL------------------AAA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 179 VSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPsaptlvlAPVPTPVLAPMPASTPPAAPAPPSVP 258
Cdd:PRK12323 437 RQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARA-------APAAAPAPADDDPPPWEELPPEFASP 509
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462630480 259 MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSR 321
Cdd:PRK12323 510 APAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
1320-1399 |
1.17e-06 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 53.36 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1320 ILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASS----DTMKRFLSDHLSDLQGRA 1395
Cdd:PTZ00322 100 ILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEEngfrEVVQLLSRHSQCHFELGA 179
|
....
gi 2462630480 1396 EGDP 1399
Cdd:PTZ00322 180 NAKP 183
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
120-566 |
1.78e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 52.85 E-value: 1.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 120 PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAP-PSGPVP 198
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPsPHPPLQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 199 LSAPAPAPLSVPVSAPPLALIQAPVPP------SAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPStp 272
Cdd:pfam03154 251 PMTQPPPPSQVSPQPLPQPSLHGQMPPmphslqTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTP-- 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 273 tliPAFAPTPVPAPTPAPIFTPAPTPMPAATPaaiPTSAPIPAsfslsrvcFPAAQA---PAMQKVPLSFQPGTVLtpsq 349
Cdd:pfam03154 329 ---PSQSQLQSQQPPREQPLPPAPLSMPHIKP---PPTTPIPQ--------LPNPQShkhPPHLSGPSPFQMNSNL---- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 350 plvyiPPPSCGQPLSvaTLPTTLGVSStlTLPVLPSYLQDRCLPGVLASPelrsypyafsvarPLTSDSKLVSLEVNRLP 429
Cdd:pfam03154 391 -----PPPPALKPLS--SLSTHHPPSA--HPPPLQLMPQSQQLPPPPAQP-------------PVLTQSQSLPPPAASHP 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 430 CTSPSGSTTTQP-------APDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPphpakMPSGTEQQTEGTSVTFSP 502
Cdd:pfam03154 449 PTSGLHQVPSQSpfpqhpfVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSGP-----VPAAVSCPLPPVQIKEEA 523
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 503 LKSPPQLEremaSPPecsempldlssksnrqklPLPNQRKTPPMPVLTPVHTSSKALLSTVLSR 566
Cdd:pfam03154 524 LDEAEEPE----SPP------------------PPPRSPSPEPTVVNTPSHASQSARFYKHLDR 565
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
1294-1372 |
2.24e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 51.89 E-value: 2.24e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462630480 1294 DVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAM 1372
Cdd:PHA02874 116 DVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPL 194
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
1303-1391 |
2.26e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 51.97 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1303 YTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVH-----DAVVNDNLETIWLLLSYGADPTLATYSGQT-----AM 1372
Cdd:PHA03100 36 VLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHylsniKYNLTDVKEIVKLLLEYGANVNAPDNNGITpllyaIS 115
|
90
....*....|....*....
gi 2462630480 1373 KLASSDTMKRFLSDHLSDL 1391
Cdd:PHA03100 116 KKSNSYSIVEYLLDNGANV 134
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
1280-1375 |
2.66e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 51.80 E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1280 YKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWT-DILNILLEHGANVNC-SAQDGTRPVHDAVVNDnlETIWLLLSY 1357
Cdd:PHA02878 212 YNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDyDILKLLLEHGVDVNAkSYILGLTALHSSIKSE--RKLKLLLEY 289
|
90
....*....|....*...
gi 2462630480 1358 GADPTLATYSGQTAMKLA 1375
Cdd:PHA02878 290 GADINSLNSYKLTPLSSA 307
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
1270-1322 |
2.88e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.73 E-value: 2.88e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462630480 1270 TLLQRAARLGYKDVVLYCLQKdSEDVNHRDNAGYTALHEACSRGWTDILNILL 1322
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEK-GADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
1288-1340 |
5.14e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.03 E-value: 5.14e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462630480 1288 LQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVH 1340
Cdd:pfam13857 2 LEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALD 54
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
1288-1360 |
5.78e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 50.79 E-value: 5.78e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462630480 1288 LQKDSEDVNHRDNAGYTALHEACSRGW---TDILNILLEHGANVNCSAQDGTRPVHDAVVNDN-LETIWLLLSYGAD 1360
Cdd:PHA03095 33 LLAAGADVNFRGEYGKTPLHLYLHYSSekvKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATtLDVIKLLIKAGAD 109
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
1302-1330 |
6.26e-06 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 44.12 E-value: 6.26e-06
10 20
....*....|....*....|....*....
gi 2462630480 1302 GYTALHEACSRGWTDILNILLEHGANVNC 1330
Cdd:smart00248 2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
189-551 |
1.60e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.94 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 189 ASAPPSGPVPLSAPAPAPLSVPVSAPPlaliQAPVP-PSAPTlVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSG 267
Cdd:PHA03247 2544 ASDDAGDPPPPLPPAAPPAAPDRSVPP----PRPAPrPSEPA-VTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLP 2618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 268 PPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAA--QAPAMQKVPLSFQPGTVL 345
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSppQRPRRRAARPTVGSLTSL 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 346 T--PSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSL 423
Cdd:PHA03247 2699 AdpPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAG 2778
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 424 EVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQ----PLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVT 499
Cdd:PHA03247 2779 PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAAspagPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAP 2858
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462630480 500 FSPLKSPPQLEREMASP-----PECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTP 551
Cdd:PHA03247 2859 GGDVRRRPPSRSPAAKPaaparPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPP 2915
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
1302-1330 |
4.01e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 41.89 E-value: 4.01e-05
10 20 30
....*....|....*....|....*....|
gi 2462630480 1302 GYTALHEACSR-GWTDILNILLEHGANVNC 1330
Cdd:pfam00023 2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNA 31
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
1294-1357 |
4.09e-05 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 48.36 E-value: 4.09e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 1294 DVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSY 1357
Cdd:PTZ00322 107 DPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
1302-1330 |
9.77e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 40.70 E-value: 9.77e-05
10 20
....*....|....*....|....*....
gi 2462630480 1302 GYTALHEACSRGWTDILNILLEHGANVNC 1330
Cdd:pfam13606 2 GNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
1294-1377 |
1.27e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 46.41 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1294 DVNHRD-NAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAM 1372
Cdd:PHA02878 159 DINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPL 238
|
....*
gi 2462630480 1373 KLASS 1377
Cdd:PHA02878 239 HISVG 243
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
1288-1351 |
1.45e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 46.60 E-value: 1.45e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 1288 LQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETI 1351
Cdd:PHA02876 164 LLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTI 227
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
1262-1329 |
3.21e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 45.04 E-value: 3.21e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462630480 1262 IVNKNA-GETLLQRAARLGYKDVVLYCLQKdSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVN 1329
Cdd:PHA03100 185 INIKDVyGFTPLHYAVYNNNPEFVKYLLDL-GANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIK 252
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
1294-1389 |
3.48e-04 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 45.02 E-value: 3.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1294 DVNHRDNAGYTALHEA---CSRGWTDILNiLLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQT 1370
Cdd:PHA03095 214 DPAATDMLGNTPLHSMatgSSCKRSLVLP-LLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNT 292
|
90 100
....*....|....*....|...
gi 2462630480 1371 AMKLA----SSDTMKRFLSDHLS 1389
Cdd:PHA03095 293 PLSLMvrnnNGRAVRAALAKNPS 315
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
1288-1384 |
4.11e-04 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 45.24 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1288 LQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGA--DPTLAT 1365
Cdd:PLN03192 544 LLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILYHFASisDPHAAG 623
|
90
....*....|....*....
gi 2462630480 1366 YSGQTAMKLASSDTMKRFL 1384
Cdd:PLN03192 624 DLLCTAAKRNDLTAMKELL 642
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
1261-1360 |
9.72e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 43.85 E-value: 9.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1261 LIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHG---ANVNCSAQ--DG 1335
Cdd:cd22192 10 LLQQKRISESPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelVNEPMTSDlyQG 89
|
90 100
....*....|....*....|....*
gi 2462630480 1336 TRPVHDAVVNDNLETIWLLLSYGAD 1360
Cdd:cd22192 90 ETALHIAVVNQNLNLVRELIARGAD 114
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
1269-1375 |
1.05e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 43.41 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1269 ETLLQRAARLGYKDVVlYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNL 1348
Cdd:PHA02874 125 KTFLHYAIKKGDLESI-KMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDY 203
|
90 100
....*....|....*....|....*..
gi 2462630480 1349 ETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:PHA02874 204 ACIKLLIDHGNHIMNKCKNGFTPLHNA 230
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
99-238 |
1.08e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.55 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 99 SPLPAPICPPAPGSASVPHSVPdafqVPLSVPAPVPHsglvPVQVATSVPAPSPPLAPVPALApappsvptlisdSNPLS 178
Cdd:PRK14951 372 AAAPAEKKTPARPEAAAPAAAP----VAQAAAAPAPA----AAPAAAASAPAAPPAAAPPAPV------------AAPAA 431
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462630480 179 VSASVLVPVPASAPPSGPVPLSAPAPAPLSVPV-SAPPLALIQAPVPPSAPTLVLAPVPTP 238
Cdd:PRK14951 432 AAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVrVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
1268-1360 |
1.27e-03 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 43.32 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1268 GETLLQRAARLGYKDVVLYCLqKDSEDVNHRDNAGYTALHEACSRGWTDILNI--------------------------- 1320
Cdd:PLN03192 558 GRTPLHIAASKGYEDCVLVLL-KHACNVHIRDANGNTALWNAISAKHHKIFRIlyhfasisdphaagdllctaakrndlt 636
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2462630480 1321 ----LLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGAD 1360
Cdd:PLN03192 637 amkeLLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGAD 680
|
|
| PRK05641 |
PRK05641 |
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated |
173-224 |
1.53e-03 |
|
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
Pssm-ID: 235540 [Multi-domain] Cd Length: 153 Bit Score: 40.62 E-value: 1.53e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 2462630480 173 DSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSApplALIQAPVP 224
Cdd:PRK05641 44 DLSAVQEQVPTPAPAPAPAVPSAPTPVAPAAPAPAPASAGE---NVVTAPMP 92
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
1280-1362 |
1.69e-03 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 42.70 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1280 YKDVVLyCLQKDSEDVNHRDNAGYTALH-EACSRGWTDILNILLEHGANVNCSAQDGTRPVHD--AVVNDNLETIWLLLS 1356
Cdd:PHA03095 62 VKDIVR-LLLEAGADVNAPERCGFTPLHlYLYNATTLDVIKLLIKAGADVNAKDKVGRTPLHVylSGFNINPKVIRLLLR 140
|
....*.
gi 2462630480 1357 YGADPT 1362
Cdd:PHA03095 141 KGADVN 146
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
1321-1375 |
2.70e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 37.33 E-value: 2.70e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462630480 1321 LLEHG-ANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLA 1375
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02795 |
PHA02795 |
ankyrin-like protein; Provisional |
1293-1335 |
2.86e-03 |
|
ankyrin-like protein; Provisional
Pssm-ID: 165157 [Multi-domain] Cd Length: 437 Bit Score: 41.90 E-value: 2.86e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462630480 1293 EDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDG 1335
Cdd:PHA02795 212 EDINQLDAGGRTLLYRAIYAGYIDLVSWLLENGANVNAVMSNG 254
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
176-239 |
2.98e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.01 E-value: 2.98e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 176 PLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLAlIQAPVPPSAPTLVLAPVPTPV 239
Cdd:PRK14951 391 AAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAA-APAAAPAAAPAAVALAPAPPA 453
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
176-471 |
3.23e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 176 PLSVSASVLVPVPASAPPSG--PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPvptpvlapmpastppaapa 253
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAaaPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAA------------------- 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 254 ppsvpmptptpssgppstptlipafaptpvpaPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQ 333
Cdd:PRK12323 436 --------------------------------ARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARA 483
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 334 KVPLSFQPGTVLTPsqPLVYIPPpscgqplsvatlpttlgvsstlTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARP 413
Cdd:PRK12323 484 APAAAPAPADDDPP--PWEELPP----------------------EFASPAPAQPDAAPAGWVAESIPDPATADPDDAFE 539
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462630480 414 ltsdsklvSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLP 471
Cdd:PRK12323 540 --------TLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLP 589
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
1316-1377 |
3.59e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 41.57 E-value: 3.59e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 1316 DILNILLEHGANVNCSAQDGTRPVHDAVVN--DNLETIWLLLSYGADPTLATYSGQTAMKLASS 1377
Cdd:PHA03100 87 EIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLLHLYLE 150
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
108-237 |
3.88e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.76 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 108 PAPGSASVPHSVPDAfQVPLSVPAPVPHSGLVPvqvATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASvlVPV 187
Cdd:PRK07003 360 PAVTGGGAPGGGVPA-RVAGAVPAPGARAAAAV---GASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAP--APP 433
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2462630480 188 PASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPT 237
Cdd:PRK07003 434 ATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASD 483
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
183-373 |
3.92e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 41.62 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 183 VLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPlaliqAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP 262
Cdd:PRK14951 357 VLLRLLAFKPAAAAEAAAPAEKKTPARPEAAAP-----AAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAA 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 263 TPssgppstptlipafaptpvpaptpapiftPAPTPMPAATPAAIPTSAPIPAsfslsrvcfpaaqAPAMQKVPLSFQPG 342
Cdd:PRK14951 432 AA-----------------------------PAAAPAAAPAAVALAPAPPAQA-------------APETVAIPVRVAPE 469
|
170 180 190
....*....|....*....|....*....|.
gi 2462630480 343 TVLTPSqplvyiPPPSCGQPLSVATLPTTLG 373
Cdd:PRK14951 470 PAVASA------APAPAAAPAAARLTPTEEG 494
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
82-255 |
5.49e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.37 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 82 GTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPdafqVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALA 161
Cdd:PRK07003 363 TGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTA----VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 162 PAPPSVPTLisdsnPLSVSASVLVPVPASAPPSGPVPLSAPAPAplSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLA 241
Cdd:PRK07003 439 GDDAADGDA-----PVPAKANARASADSRCDERDAQPPADSGSA--SAPASDAPPDAAFEPAPRAAAPSAATPAAVPDAR 511
|
170
....*....|....
gi 2462630480 242 PMPASTPPAAPAPP 255
Cdd:PRK07003 512 APAAASREDAPAAA 525
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
1317-1386 |
7.17e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 40.82 E-value: 7.17e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462630480 1317 ILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASS----DTMKRFLSD 1386
Cdd:PHA02876 160 IAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDskniDTIKAIIDN 233
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
99-231 |
7.21e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 41.00 E-value: 7.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 99 SPLPAPICPPA---PGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSN 175
Cdd:PRK07994 363 APLPEPEVPPQsaaPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSE 442
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462630480 176 PLSVSASV--------LVPVPASAPPSGPVPLSAPA-------PAPLSVPVSAPPLALIQAPVPPSAPTLV 231
Cdd:PRK07994 443 PAAASRARpvnsalerLASVRPAPSALEKAPAKKEAyrwkatnPVEVKKEPVATPKALKKALEHEKTPELA 513
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
99-240 |
7.44e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 40.74 E-value: 7.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 99 SPLPAPICPPAPGSASVPHSVPDAFQ---------VPLSVPAPVPHSGLVPVQV-ATSVPAPSPPLAPVPALAPAPPSVP 168
Cdd:PRK12727 77 TKPAAPVHAPLKLSANANMSQRQRVAsaaedmiaaMALRQPVSVPRQAPAAAPVrAASIPSPAAQALAHAAAVRTAPRQE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 169 TLISdSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLA-------------------LIQAPVPPSAPT 229
Cdd:PRK12727 157 HALS-AVPEQLFADFLTTAPVPRAPVQAPVVAAPAPVPAIAAALAAHAAyaqdddeqldddgfdlddaLPQILPPAALPP 235
|
170
....*....|.
gi 2462630480 230 LVLAPVPTPVL 240
Cdd:PRK12727 236 IVVAPAAPAAL 246
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
180-308 |
7.48e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.85 E-value: 7.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 180 SASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPM 259
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVA 446
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2462630480 260 PTPTPSSGPPSTPTLIPAFAPTPVPaptpapifTPAPTPMPAATPAAIP 308
Cdd:PRK14951 447 LAPAPPAQAAPETVAIPVRVAPEPA--------VASAAPAPAAAPAAAR 487
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
122-253 |
7.80e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.85 E-value: 7.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 122 AFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSvptlisdsnPLSVSASVLVPVPASAPPSGPVPLSA 201
Cdd:PRK14951 363 AFKPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAP---------AAAASAPAAPPAAAPPAPVAAPAAAA 433
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462630480 202 PAPAPLSVPVSAPPlalIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 253
Cdd:PRK14951 434 PAAAPAAAPAAVAL---APAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAA 482
|
|
| PHA02716 |
PHA02716 |
CPXV016; CPX019; EVM010; Provisional |
1284-1372 |
7.87e-03 |
|
CPXV016; CPX019; EVM010; Provisional
Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 41.05 E-value: 7.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1284 VLYCLQKDSEDVNHRDNAGYTALHEACSRGW--TDILNILLEHGANVNCSAQDGTRPVHD-----AVVND---------N 1347
Cdd:PHA02716 299 VVYSFLQPGVKLHYKDSAGRTCLHQYILRHNisTDIIKLLHEYGNDLNEPDNIGNTVLHTylsmlSVVNIldpetdndiR 378
|
90 100
....*....|....*....|....*
gi 2462630480 1348 LETIWLLLSYGADPTLATYSGQTAM 1372
Cdd:PHA02716 379 LDVIQCLISLGADITAVNCLGYTPL 403
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
116-239 |
8.77e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 40.62 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 116 PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSG 195
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2462630480 196 PVPLSAPAPAPLSVPV----SAPPLALIQAPVPPSAPTLVLAPVPTPV 239
Cdd:PRK07994 441 SEPAAASRARPVNSALerlaSVRPAPSALEKAPAKKEAYRWKATNPVE 488
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
1285-1377 |
9.76e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 40.36 E-value: 9.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462630480 1285 LYCLQKDSEDVNHRDnaGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLA 1364
Cdd:PHA02875 87 LLDLGKFADDVFYKD--GMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIE 164
|
90
....*....|...
gi 2462630480 1365 TYSGQTAMKLASS 1377
Cdd:PHA02875 165 DCCGCTPLIIAMA 177
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
174-239 |
9.88e-03 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 40.26 E-value: 9.88e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462630480 174 SNPLSVSASVlvPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTlvlAPVPTPV 239
Cdd:TIGR00601 75 SKPKTGTGKV--APPAATPTSAPTPTPSPPASPASGMSAAPASAVEEKSPSEESAT---ATAPESP 135
|
|
| |
