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presenilin-associated rhomboid-like protein, mitochondrial isoform X5 [Homo sapiens]
rhomboid family protein( domain architecture ID 10483871)
rhomboid family protein may be an intramembrane serine protease that catalyzes regulated intramembrane proteolysis, resulting in the release of functional polypeptides from their membrane anchors, or an inactive rhomboid protein that lacks the conserved active sites and has no peptidase activity
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
18-159 | 6.90e-25 | |||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. : Pssm-ID: 426384 Cd Length: 147 Bit Score: 94.60 E-value: 6.90e-25
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Name | Accession | Description | Interval | E-value | |||
Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
18-159 | 6.90e-25 | |||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Pssm-ID: 426384 Cd Length: 147 Bit Score: 94.60 E-value: 6.90e-25
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GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
18-160 | 1.26e-20 | |||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 84.91 E-value: 1.26e-20
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Name | Accession | Description | Interval | E-value | |||
Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
18-159 | 6.90e-25 | |||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Pssm-ID: 426384 Cd Length: 147 Bit Score: 94.60 E-value: 6.90e-25
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GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
18-160 | 1.26e-20 | |||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 84.91 E-value: 1.26e-20
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Blast search parameters | ||||
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