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Conserved domains on  [gi|2462596094|ref|XP_054205468|]
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cystine/glutamate transporter isoform X2 [Homo sapiens]

Protein Classification

2A0308 family protein( domain architecture ID 11489956)

2A0308 family protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 18-513 0e+00

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


:

Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 677.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  18 KPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIW 97
Cdd:TIGR00911   4 GRVFRSQSNATNYQFSSSGRKKSVSASTVDGGEAVALKKEITLLSGVGIIVGTIIGSGIFVSPKGVLKNAGSVGLALIMW 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  98 TVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPEL 177
Cdd:TIGR00911  84 AVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGPLLAFLRLWIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEW 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 178 AIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQ--NFKDAFSGRDSSITRLPLAFYY 255
Cdd:TIGR00911 164 AIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVQLGKGGVEslNPKNAFEGTETSAGGIVLAFYS 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 256 GMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPI 335
Cdd:TIGR00911 244 GIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPA 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 336 FVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIG 415
Cdd:TIGR00911 324 LVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNA 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 416 LAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMS 495
Cdd:TIGR00911 404 LAVAGLLWLRYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLYSPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLI 483

                         490
                  ....*....|....*...
gi 2462596094 496 EKITRTLQIILEVVPEED 513
Cdd:TIGR00911 484 VSKTVLLQKVLEVVKPQK 501
 
Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 18-513 0e+00

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 677.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  18 KPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIW 97
Cdd:TIGR00911   4 GRVFRSQSNATNYQFSSSGRKKSVSASTVDGGEAVALKKEITLLSGVGIIVGTIIGSGIFVSPKGVLKNAGSVGLALIMW 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  98 TVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPEL 177
Cdd:TIGR00911  84 AVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGPLLAFLRLWIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEW 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 178 AIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQ--NFKDAFSGRDSSITRLPLAFYY 255
Cdd:TIGR00911 164 AIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVQLGKGGVEslNPKNAFEGTETSAGGIVLAFYS 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 256 GMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPI 335
Cdd:TIGR00911 244 GIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPA 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 336 FVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIG 415
Cdd:TIGR00911 324 LVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNA 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 416 LAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMS 495
Cdd:TIGR00911 404 LAVAGLLWLRYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLYSPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLI 483

                         490
                  ....*....|....*...
gi 2462596094 496 EKITRTLQIILEVVPEED 513
Cdd:TIGR00911 484 VSKTVLLQKVLEVVKPQK 501
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
49-481 4.33e-62

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 209.37  E-value: 4.33e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  49 QEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGsvGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYI 128
Cdd:COG0531     4 GESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAG--PAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 129 LEVFGPLPAFVRVWVeLLIIRPAATAVISLAFGRYiLEPFFiqceiPELAIKLITAVGITVVMVLNSMSVSWSARIQIFL 208
Cdd:COG0531    82 RRALGPLLGFLAGWA-LLLSYVLAVAAVAVAFGGY-LSSLF-----PAGGSVLIALVLILLLTLLNLRGVKESAKVNNIL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 209 TFCKLTAILIIIVPGvmqLIKGQTQNFkDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISM 288
Cdd:COG0531   155 TVLKLLVLLLFIVVG---LFAFDPANF-TPFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 289 AIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGN-FSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPE 367
Cdd:COG0531   231 LIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPwGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPK 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 368 ILSMIHVRKHTPLPAVIVLHPLTMIMLFSG--DLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALF 445
Cdd:COG0531   311 VFAKVHPRFGTPVNAILLTGVIALLLLLLGaaSFTALASLASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLPLIPIL 390

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 2462596094 446 SFtcLFMVALSLYSDPFSTGIGFVITLTGVPAYYLF 481
Cdd:COG0531   391 GI--LLCLFLLYLLGPGALLIGLVLLAIGLLLYLLY 424
AA_permease_2 pfam13520
Amino acid permease;
83-475 1.29e-39

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 148.61  E-value: 1.29e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  83 VLQNTGSVGMSLTIW--TVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 160
Cdd:pfam13520  21 VAPLVASGGPALIVWgwIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAA 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 161 GrYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKL--TAILIIIVPGVMQLIKGQTQNFKDA 238
Cdd:pfam13520 101 S-YLLSALGPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLllPLILIIILGLVTADGGGFNLLSGEW 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 239 FSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVenPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVA 318
Cdd:pfam13520 180 HTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEV--KKRNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLG 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 319 VTFS--ERLLGN--FSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKH-TPLPAVIVLHPLTMIM 393
Cdd:pfam13520 258 QVAAllFQAVGGkwGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFgSPIRAIILTAILSLIL 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 394 LF-----SGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGF 468
Cdd:pfam13520 338 LLlfllsPAAYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRIPGRWPVAIFGILFSLFLIVALFFPPVGPATGSSL 417


                  ....*..
gi 2462596094 469 VITLTGV 475
Cdd:pfam13520 418 NYAIILI 424
frlA PRK11357
amino acid permease;
49-489 7.82e-19

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 88.76  E-value: 7.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  49 QEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYI 128
Cdd:PRK11357    1 MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 129 LEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYIlePFFIqcEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFL 208
Cdd:PRK11357   81 KNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNL--GFLT--PIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 209 TFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISM 288
Cdd:PRK11357  157 TIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSC 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 289 AIVTIGYVLTNVAYFTTINAEELLLSN---AVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHL 365
Cdd:PRK11357  237 LLVLVLYTLLALVISGLMPFDKLANSEtpiSDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLF 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 366 PEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKcPDMHRPFKVPLF--IPA 443
Cdd:PRK11357  317 FKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKR-DDYKPLWRTPAFglMTT 395

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 2462596094 444 LFSFTCLFMVALSLYSDPFSTGI-GFVITLTGVPAYYLfiiWDKKPR 489
Cdd:PRK11357  396 LAIASSLILVASTFVWAPIPGLIcAVIVIATGLPAYAF---WAKRSR 439
 
Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 18-513 0e+00

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 677.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  18 KPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIW 97
Cdd:TIGR00911   4 GRVFRSQSNATNYQFSSSGRKKSVSASTVDGGEAVALKKEITLLSGVGIIVGTIIGSGIFVSPKGVLKNAGSVGLALIMW 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  98 TVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPEL 177
Cdd:TIGR00911  84 AVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGPLLAFLRLWIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEW 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 178 AIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQ--NFKDAFSGRDSSITRLPLAFYY 255
Cdd:TIGR00911 164 AIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVQLGKGGVEslNPKNAFEGTETSAGGIVLAFYS 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 256 GMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPI 335
Cdd:TIGR00911 244 GIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPA 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 336 FVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIG 415
Cdd:TIGR00911 324 LVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNA 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 416 LAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMS 495
Cdd:TIGR00911 404 LAVAGLLWLRYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLYSPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLI 483

                         490
                  ....*....|....*...
gi 2462596094 496 EKITRTLQIILEVVPEED 513
Cdd:TIGR00911 484 VSKTVLLQKVLEVVKPQK 501
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
49-481 4.33e-62

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 209.37  E-value: 4.33e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  49 QEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGsvGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYI 128
Cdd:COG0531     4 GESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAG--PAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 129 LEVFGPLPAFVRVWVeLLIIRPAATAVISLAFGRYiLEPFFiqceiPELAIKLITAVGITVVMVLNSMSVSWSARIQIFL 208
Cdd:COG0531    82 RRALGPLLGFLAGWA-LLLSYVLAVAAVAVAFGGY-LSSLF-----PAGGSVLIALVLILLLTLLNLRGVKESAKVNNIL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 209 TFCKLTAILIIIVPGvmqLIKGQTQNFkDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISM 288
Cdd:COG0531   155 TVLKLLVLLLFIVVG---LFAFDPANF-TPFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 289 AIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGN-FSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPE 367
Cdd:COG0531   231 LIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPwGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPK 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 368 ILSMIHVRKHTPLPAVIVLHPLTMIMLFSG--DLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALF 445
Cdd:COG0531   311 VFAKVHPRFGTPVNAILLTGVIALLLLLLGaaSFTALASLASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLPLIPIL 390

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 2462596094 446 SFtcLFMVALSLYSDPFSTGIGFVITLTGVPAYYLF 481
Cdd:COG0531   391 GI--LLCLFLLYLLGPGALLIGLVLLAIGLLLYLLY 424
AA_permease_2 pfam13520
Amino acid permease;
83-475 1.29e-39

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 148.61  E-value: 1.29e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  83 VLQNTGSVGMSLTIW--TVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 160
Cdd:pfam13520  21 VAPLVASGGPALIVWgwIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAA 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 161 GrYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKL--TAILIIIVPGVMQLIKGQTQNFKDA 238
Cdd:pfam13520 101 S-YLLSALGPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLllPLILIIILGLVTADGGGFNLLSGEW 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 239 FSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVenPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVA 318
Cdd:pfam13520 180 HTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEV--KKRNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLG 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 319 VTFS--ERLLGN--FSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKH-TPLPAVIVLHPLTMIM 393
Cdd:pfam13520 258 QVAAllFQAVGGkwGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFgSPIRAIILTAILSLIL 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 394 LF-----SGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGF 468
Cdd:pfam13520 338 LLlfllsPAAYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRIPGRWPVAIFGILFSLFLIVALFFPPVGPATGSSL 417


                  ....*..
gi 2462596094 469 VITLTGV 475
Cdd:pfam13520 418 NYAIILI 424
2A0305 TIGR00908
ethanolamine permease; The three genes used as the seed for this model (from Burkholderia ...
 84-481 7.15e-28

ethanolamine permease; The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129986 [Multi-domain]  Cd Length: 442  Bit Score: 115.71  E-value: 7.15e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  84 LQNTGSVGMSLTIWTVCGVLSLFgALSYAELGTTIKKSGGHYTYILEVFGPLPAF---VRVWVELLIirpaATAVISLAF 160
Cdd:TIGR00908  34 LAQGGWGGFVVATLLVATMYLTF-CFSLAELSTMIPTAGGGYGFARRAFGPWGGFlagTAILIEFAF----APPAIACFI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 161 GRYIlepffiQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFckLTAILIIIVPGVMQLIKGQTQNFKDAFS 240
Cdd:TIGR00908 109 GAYC------ESLFPVGPGWLAALVFYIVFIGINILGVGEAAKLEFVVTA--VAIIALGVFIGAMVPHFDSANLFNGPQT 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 241 GRDSSitrLPLAfYYGMYA---YAGWFYLN-----FVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELL 312
Cdd:TIGR00908 181 GASSF---LPGA-YVGVFAaipFAIWFFLAvegvaMAAEETKNPKRDIPRGLIGAILTLLALAAGILVVGPGAADAKELM 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 313 LSNAVAVTFSERLLGNFSLAVPIFVALSCFG---SMNGGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAVIVLHPL 389
Cdd:TIGR00908 257 GSNNPLPEALESIYGGSTWMSQFVNLVGLFGliaSFHGIIYGYSRQIFALSRAGYLPESLSKVN-RKKAPVLAIVVPGVI 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 390 TMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFI--PAL-FSFTCLFMVAlSLYSDPFSTGI 466
Cdd:TIGR00908 336 GFGLSLTGQTALIILVSVFGAIISYVLSMAAHFTLRIRRPDMERPYRTPGGIltPGVaLVLACVALVT-GFYVDPRVVVG 414

                         410
                  ....*....|....*
gi 2462596094 467 GFVITLTGVPAYYLF 481
Cdd:TIGR00908 415 AVAIFVVLIGYYFLY 429
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 99-427 5.28e-23

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 102.59  E-value: 5.28e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  99 VCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELL--IIRPAATA---------VISLAFGRYILEP 167
Cdd:TIGR00906  70 ISGLAAVLSGFCYAEFGARVPKAGSAYLYSYVTVGELWAFITGWNLILeyVIGTAAVArswsayfdeLLNKQIGQFRRTY 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 168 FFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGvmqLIKGQTQNFKDAFSGRDSSIT 247
Cdd:TIGR00906 150 FKLNYDGLAEYPDFFAVCLILLLAVLLSFGVKESAWVNKIFTAINILVLLFVIIAG---FTKADVANWSITEEKGAGGFM 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 248 rlPLAFYYGM-------YAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVT 320
Cdd:TIGR00906 227 --PYGFTGVLsgaatcfFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDPDAPFPVA 304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 321 FSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLD 400
Cdd:TIGR00906 305 FEYVGWDPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQINSKTKTPINATVVSGAIAALMAFLFDLK 384

                         330       340
                  ....*....|....*....|....*..
gi 2462596094 401 SLLNFLSFARWLFIGLAVAGLIYLRYK 427
Cdd:TIGR00906 385 ALVDLLSIGTLLAYSLVAACVLILRYQ 411
AA_permease pfam00324
Amino acid permease;
87-488 4.90e-19

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 89.69  E-value: 4.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  87 TGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLiirpaaTAVISLAFGRYILE 166
Cdd:pfam00324  25 QAGPAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGWNYWL------SWITVLALELTAAS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 167 PFFIQCE-IPELAIKLITAVGITVVMVLNSM-SVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDS 244
Cdd:pfam00324  99 ILIQFWElVPDIPYLWVWGAVFLVLLTIINLvGVKWYGEAEFWFALIKIIAIIGFIIVGIILLSGGNPNDGAIFRYLGDN 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 245 SITRLPLAFYYG---------MYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSN 315
Cdd:pfam00324 179 GGKNNFPPGFGKgfisvfviaFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLN 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 316 AVAVTFSERLLGNFSLAVPIFVAL-------SCFGSMNGGVFAVSRLFYVASREGHLPEILsMIHVRKHTPLPAVIVlhp 388
Cdd:pfam00324 259 DSASAASPFVIFFKFLGISGLAPLinaviltAALSAANSSLYSGSRMLYSLARDGLAPKFL-KKVDKRGVPLRAILV--- 334

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 389 lTMIMLFSGDLDSLLNFLSFARWL-----FIGLAVAGLIYLRYkcPDMHRPFKVPLFIPALFSFTCLFMVALSLYsdpfs 463
Cdd:pfam00324 335 -SMVISLLALLLASLNPAIVFNFLlaisgLSGLIVWGLISLSH--LRFRKAFKYQGRSIDELPFKAPLGPLGVIL----- 406

                         410       420
                  ....*....|....*....|....*
gi 2462596094 464 tGIGFVITLTGVPAYYLFIIWDKKP 488
Cdd:pfam00324 407 -GLAAIIIILIIQFLYAFLPVPGGP 430
frlA PRK11357
amino acid permease;
49-489 7.82e-19

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 88.76  E-value: 7.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  49 QEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYI 128
Cdd:PRK11357    1 MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 129 LEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYIlePFFIqcEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFL 208
Cdd:PRK11357   81 KNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNL--GFLT--PIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 209 TFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISM 288
Cdd:PRK11357  157 TIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSC 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 289 AIVTIGYVLTNVAYFTTINAEELLLSN---AVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHL 365
Cdd:PRK11357  237 LLVLVLYTLLALVISGLMPFDKLANSEtpiSDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLF 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 366 PEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKcPDMHRPFKVPLF--IPA 443
Cdd:PRK11357  317 FKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKR-DDYKPLWRTPAFglMTT 395

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 2462596094 444 LFSFTCLFMVALSLYSDPFSTGI-GFVITLTGVPAYYLfiiWDKKPR 489
Cdd:PRK11357  396 LAIASSLILVASTFVWAPIPGLIcAVIVIATGLPAYAF---WAKRSR 439
PRK10644 PRK10644
arginine/agmatine antiporter;
84-396 3.07e-08

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 55.95  E-value: 3.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  84 LQNTGSVGMSLTIWTVCGVLSLfgALSYAELGTTIKKSGGHYTYILEVFGPLPAF---VRVWVELlIIRPAATAVISLAF 160
Cdd:PRK10644   35 LASTGGIAIYGWLVTIIGALGL--SMVYAKMSSLDPSPGGSYAYARRCFGPFLGYqtnVLYWLAC-WIGNIAMVVIGVGY 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 161 GRYilepFFiqceiPELAIKLITAVGITVVM----VLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMqLIKGQTqnFK 236
Cdd:PRK10644  112 LSY----FF-----PILKDPLVLTITCVVVLwifvLLNIVGPKMITRVQAVATVLALIPIVGIAVFGWF-WFRGET--YM 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 237 DAF--SGRdSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLS 314
Cdd:PRK10644  180 AAWnvSGL-GTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYVLSSTAIMGMIPNAALRVS 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 315 NAVAVTFSERLLGNFSLA-VPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAVIVLHPLTMIM 393
Cdd:PRK10644  259 ASPFGDAARMALGDTAGAiVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVN-KAGTPVAGLLIVGVLMTIF 337


                  ...
gi 2462596094 394 LFS 396
Cdd:PRK10644  338 QLS 340
PRK11021 PRK11021
putative transporter; Provisional
 93-386 1.35e-07

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 53.76  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  93 SLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGryilepfFIQC 172
Cdd:PRK11021   34 SLWAWPLLILLIFPIAIVFARLGRHFPHAGGPAHFVGMAFGPRLGRVTGWLFLSVIPVGLPAALQIAAG-------FGQA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 173 EIPE-----LAIKLITavgITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLikgQTQNFKDAFSGRDSSI- 246
Cdd:PRK11021  107 LFGWsswqlLLAELLT---LALLWLLNLRGASSSANLQTVIALLIVALVVAIWWAGDIKP---ADIPFPAPGSIEWSGLf 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 247 TRLPLAF--YYGMYAYAgwfylnFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSER 324
Cdd:PRK11021  181 AALGVMFwcFVGIEAFA------HLASEFKNPERDFPRALMIGLLLAGLVYWACTVVVLHFPAYGDKQAAAASLPGIFVQ 254

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462596094 325 LLGNFSLAV-PIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRkHTPLPAVIVL 386
Cdd:PRK11021  255 LFGGYALWViCVIGYLACFASVNIYTQSFARLVWSQAREGRPPSYLARLSAR-GVPVNALNAV 316
potE PRK10655
putrescine transporter; Provisional
 86-451 7.18e-07

putrescine transporter; Provisional


Pssm-ID: 182622  Cd Length: 438  Bit Score: 51.57  E-value: 7.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  86 NTGSVG-MSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVW---VELLIirpAATAVISLAFG 161
Cdd:PRK10655   32 KLAQVGtISILSWLVTAVGSMALAYAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYtygVSLLI---ANVAIAISAVG 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 162 rYILEpfFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFltfckltAILIIIVPGVMQLIKG----QTQNFKD 237
Cdd:PRK10655  109 -YGTE--LFGATLSPVQICLATIGVLWLCTVANFGGARITGQISSV-------TVWGVIIPVVGLSIIGwfwfSPSLYVA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 238 A--------FSGRDSSITRLPLAFYyGMYAYAGwfylnfVTEEVENPEKTIPLAICISMAIVTIGYVL-TNVAYFTTINA 308
Cdd:PRK10655  179 AwnphhlpfFSAVGSSIAMTLWAFL-GLESACA------NSDAVENPERNVPIAVLGGTLGAAVIYIVsTNVIAGIVPNM 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 309 EeLLLSNA-VAVTFSERL---LGNFSLAVPIfvaLSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIhVRKHTPLPAVI 384
Cdd:PRK10655  252 E-LANSTApFGLAFAQMFnptVGKIVMALMV---MSCCGSLLGWQFTIAQVFKSSADEGYFPKIFSRV-TKVDAPVQGML 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 385 ---VLHPLTMIMLFSGDLDSLLNFLsfarwlfIGLAV-----------AGLIYLRYKC---PDMHRPFKVPLFIPALFSF 447
Cdd:PRK10655  327 iivVIQSLLSLMTISPSLNSQFNVL-------VNLAVvtniipyilsmAALVIIQKVAnvpPSKAKVANFIAFVGALYSF 399


                  ....
gi 2462596094 448 TCLF 451
Cdd:PRK10655  400 YALY 403
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 189-385 3.58e-05

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 46.12  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 189 VVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMqLIKGQTQN-----FK-----DAFSGrDSSITRLP---LAFYY 255
Cdd:TIGR00913 128 FIVIINLFGVKGYGEAEFWFSSIKILAIIGFIILSII-LNCGGGPNhgyigFRywhdpGAFAG-GTIGGRFKgvcSVFVT 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 256 GMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTI--NAEELLLSNAVAVTFSERL---LGNFS 330
Cdd:TIGR00913 206 AAFSFGGTELVALTAGEAANPRKSIPRAAKRTFWRILVFYILTLFLIGFLVpyNDPRLLSSSSSSDSAASPFviaIQNHG 285

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 331 LAV-----PIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAVIV 385
Cdd:TIGR00913 286 IKVlphifNAVILISVLSAANSSLYASSRTLYALAHQGLAPKIFAYVD-RRGVPYVAVIV 344
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
 97-383 4.57e-05

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 45.89  E-value: 4.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  97 WTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVE---LLIIRPAATAVISLAFGRYILEPFFIQCE 173
Cdd:TIGR00907  53 WIIAGAGSICIALSLAELSSAYPTSGGQYFWSAKLAPPRQMPFASWMTgwfNLAGQVAGTASTDLSVAQLILGIVSLTTP 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 174 IPELAIKLITAVGI-----TVVMVLNSMSVSWSARIQIF------LTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGR 242
Cdd:TIGR00907 133 GREYIPTRWHIFGImigihLIHALINSLPTKWLPRITSSaaywslLGFLTICITLLACKSPKFNDGKFVFTNFNNSTGGW 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 243 DSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAIcisMAIVTIGYVLT---NVAYFTTINAEELLLSNAVAV 319
Cdd:TIGR00907 213 KPGGFAFLLGLLNPAWSMTGYDGTAHMAEEIENPEVVGPRAI---IGAVAIGIVTGfcfNIVLFFSMGDIDSLISSTTGQ 289

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462596094 320 TFSE---RLLGNF--SLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLP--EILSMIHVRKHTPLPAV 383
Cdd:TIGR00907 290 PIAQifyNALGNKagAIFLLCLILVTSFFCAITCMTANSRMIYAFSRDGGLPfsPLWSRVNPRTQVPLNAV 360
PRK15238 PRK15238
inner membrane transporter YjeM; Provisional
 179-297 1.12e-04

inner membrane transporter YjeM; Provisional


Pssm-ID: 237929 [Multi-domain]  Cd Length: 496  Bit Score: 44.55  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 179 IKLITAVGITVVMVLNsmsvswsariqIFLTfckLTAILIIIVPG--VMQLIKGQ--TQNFKDAFSGrdssitrlPLAFY 254
Cdd:PRK15238  157 IAKVTSIGGIAVMLLN-----------IVLL---LVSIIILILNGghFAQPIGVSsfVTSPNPAYQS--------PIAVL 214

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2462596094 255 ----YGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVL 297
Cdd:PRK15238  215 sfvvFAIFAYGGIEAVGGLVDKTENPEKNFPKGIIIAAIVISIGYSL 261
cadB PRK10435
cadaverine/lysine antiporter;
86-368 2.47e-04

cadaverine/lysine antiporter;


Pssm-ID: 182458  Cd Length: 435  Bit Score: 43.59  E-value: 2.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  86 NTGSVGmSLTIWTvcGVLSLFGALS----YAELGTTIKKSGGHYTYILEVfGPLPAFVRV-------WVELLIIRPAATA 154
Cdd:PRK10435   31 NLASIG-SIAIWG--WIISIIGAMSlayvYARLATKNPQQGGPIAYAGEI-SPAFGFQTGvlyyhanWIGNLAIGITAVS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 155 VISLAFGryilepfFIQCEIPElAIKLITAVGItvVMVLNSMSVSWSARiqifltFCKLTAILIIIvPGVMQLIKGQT-- 232
Cdd:PRK10435  107 YLSTFFP-------VLNDPIPA-GIACIAIVWV--FTFVNMLGGTWVSR------LTTIGLVLVLI-PVVGTAIVGWHwf 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 233 ------QNFKDAfSGRDSS--ITRLPLAfyygMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFT 304
Cdd:PRK10435  170 daatyaANWNTS-DTTDGHaiIKSILLC----LWAFVGVESAAVSTGMVKNPKRTVPLATMLGTGLAGIIYIAATQVISG 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462596094 305 TINAEELLLSNAVAVTFSERLLGNFSLA-VPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEI 368
Cdd:PRK10435  245 MFPASVMAASGAPFAISASTILGNWAAPlVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKV 309
PRK10238 PRK10238
aromatic amino acid transporter AroP;
121-457 6.04e-04

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 42.25  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 121 SGGHYTYilEVFGPLPAFVRVWVELLIIRPAATAVISlAFGRYIlepffiQCEIPELAIKLITAVGITVVMVLNSMSVSW 200
Cdd:PRK10238   77 SFSHFAY--KYWGSFAGFASGWNYWVLYVLVAMAELT-AVGKYI------QFWYPEIPTWVSAAVFFVVINAINLTNVKV 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 201 SARIQIFLTFCKLTAILIIIVPGVMQLIKGQ------TQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVE 274
Cdd:PRK10238  148 FGEMEFWFAIIKVIAVVAMIIFGGWLLFSGNggpqatVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEAD 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 275 NPEKTIPLAICISMAIVTIGY-----VLTNVAYFTTINAEelllSNAVAVTFSE---RLLGNFSLAVPIFVALSCFgsmN 346
Cdd:PRK10238  228 NPEQSIPKATNQVIYRILIFYigslaVLLSLMPWTRVTAD----TSPFVLIFHElgdTFVANALNIVVLTAALSVY---N 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 347 GGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAVIVLHPLTMIMLfsgdldsLLNFLS--FARWLFIGLAVAGLIYL 424
Cdd:PRK10238  301 SCVYCNSRMLFGLAQQGNAPKALASVD-KRGVPVNTILVSALVTALCV-------LINYLApeSAFGLLMALVVSALVIN 372

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 2462596094 425 RYKCPDMHRPFK-------VPLFIPALF----SFTCLFMVALSL 457
Cdd:PRK10238  373 WAMISLAHMKFRrakqeqgVVTRFPALLyplgNWICLLFMAAVL 416
proY PRK10580
putative proline-specific permease; Provisional
 127-439 7.96e-04

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 42.11  E-value: 7.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 127 YILEVFGPLPAFVRVWVELLIIRPAATAVISlAFGRYILEPFfiqceiPELAIKLITAVGITVVMVLNSMSVSWSARIQI 206
Cdd:PRK10580   78 YAQENLGPLAGYITGWTYCFEILIVAIADVT-AFGIYMGVWF------PTVPHWIWVLSVVLIICAVNLMSVKVFGELEF 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 207 FLTFCKLTAILIIIVPGVMQLI-----KGQTQNFKDAFSGR---DSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEK 278
Cdd:PRK10580  151 WFSFFKVATIIIMIVAGIGIIIwgignGGQPTGIHNLWSNGgffSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEK 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 279 TIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSC-FGSMNGGVFAVSRLFY 357
Cdd:PRK10580  231 SIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTAsLSAINSDVFGVGRMLH 310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 358 VASREGHLPEILSMIHvRKHTPLPAVIVlhpLTMIMLFSGDLDSLLN---FLSFAR-------WLFIGLAVAGLIYLRYK 427
Cdd:PRK10580  311 GMAEQGSAPKIFSKTS-RRGIPWVTVLV---MTTALLFAVYLNYIMPenvFLVIASlatfatvWVWIMILLSQIAFRRRL 386

                         330
                  ....*....|..
gi 2462596094 428 CPDMHRPFKVPL 439
Cdd:PRK10580  387 PPEEVKALKFKV 398
PRK11387 PRK11387
S-methylmethionine permease;
109-397 1.03e-03

S-methylmethionine permease;


Pssm-ID: 236904  Cd Length: 471  Bit Score: 41.76  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 109 LSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAfgryilePFFIQCEIPELAIKLITAVGIT 188
Cdd:PRK11387   66 QCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLTWTVALGSSLTAA-------GFCMQYWFPQVPVWPWCLLFCA 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 189 VVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPG---VMQLIKGQTQNFKDAFSGRDSS--ITRLPLAFYYGM----YA 259
Cdd:PRK11387  139 LIFGLNVVSTRFFAEGEFWFSLIKVVTILAFIVLGgaaIFGFIPMQDGSPAPGLRNLTAEgwFPHGGLPILMTMvavnFA 218

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 260 YAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 339
Cdd:PRK11387  219 FSGTELIGIAAGETENPAKVIPVAIRTTIARLVIFFVGTVLVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADIFNFVIL 298

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462596094 340 SCFGS-MNGGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAVIVLHPLTMIMLFSG 397
Cdd:PRK11387  299 TAILSaANSGLYASGRMLWSLSNEGTLPACFARLT-KRGIPLTALSVSMLGGLLALFSS 356
PRK10249 PRK10249
phenylalanine transporter; Provisional
 97-422 2.00e-03

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 40.74  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094  97 WTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAfgryilePFFIQCEIPE 176
Cdd:PRK10249   60 YGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAA-------GIYMQYWFPD 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 177 LAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKG---QTQNFKDAFSGRDSSITR---LP 250
Cdd:PRK10249  133 VPTWIWAAAFFIIINAVNLVNVRLYGETEFWFALIKVLAIIGMIGFGLWLLFSGhggEKASIDNLWRYGGFFATGwngLI 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 251 LAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFS 330
Cdd:PRK10249  213 LSLAVIMFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVV 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 331 LAVPIFVAL-SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAvivlhpltmiMLFSGDLDSLLNFLSF- 408
Cdd:PRK10249  293 ASALNFVILvASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTRVS-RRGVPINS----------LMLSGAITSLVVLINYl 361

                         330
                  ....*....|....*...
gi 2462596094 409 ----ARWLFIGLAVAGLI 422
Cdd:PRK10249  362 lpqkAFGLLMALVVATLL 379
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
175-500 5.79e-03

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 39.00  E-value: 5.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 175 PELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVM---QLIKGQT---QNFKDA---FSGRDSS 245
Cdd:COG0833   123 PDVPVWIWSLLFLALIFLLNALSVKAFGESEFWFSLIKVITVIAFIIVGLLmifGIIGGHApgfSNFTTGdgpFPGGFLA 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 246 ITrlpLAFYYGMYAYAGwfylnfvTE-------EVENPEKTIPLAI-CISMAIVtIGYVLTNVAYFTTINAEELLLSNAV 317
Cdd:COG0833   203 IL---GVMMIVGFSFQG-------TEligiaagESENPEKTIPKAIrQVFWRIL-LFYILAIFVIAALIPYTDAGVAESP 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 318 AVTFSERLLGNFSLAVPIFV----ALSCfgsMNGGVFAVSRLFYVASREGHLPEILSMIHvRKHTPLPAVIVlhplTMIM 393
Cdd:COG0833   272 FTLVFERAGIPYAADIMNAViltaVLSA---GNSGLYASTRMLWSLAKEGMAPKIFAKLN-KRGVPLNALLA----TMAV 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596094 394 ----LFSGDLDS------LLN---FLSFARWlfIGLAVAGLIYLR------YKCPDMhrPFKVPLF-IPALFSFTCLFMV 453
Cdd:COG0833   344 gllaLLSSFFGAgtvylwLLSisgLTGFIAW--LGIAISHYRFRRayvaqgGDLEDL--KYKAPLFpFGPIFAFILCLIV 419

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462596094 454 ALSLYSDPFstgiGFVITLTGVP---AYYLFIIWDKKPRWFRIMSEKITR 500
Cdd:COG0833   420 IIGQAFDPE----QRIALYIGIPfflACYLGYKLKKKTKLVPLEEMDLSP 465
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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