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Conserved domains on  [gi|2462622367|ref|XP_054217821|]
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centriolin isoform X22 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-261 2.33e-23

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd21340:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 220  Bit Score: 100.63  E-value: 2.33e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   89 KKLTKQDNLALIKSL-------NlslskdggkKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISK 161
Cdd:cd21340     12 KNITKIDNLSLCKNLkvlylydN---------KITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISV 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  162 IEGIENMCNLQKLNLAGNEIEhipvwLGKKL-----------KSLRVLNLKGNKISSLQDISKLKPLQDLI--------- 221
Cdd:cd21340     83 VEGLENLTNLEELHIENQRLP-----PGEKLtfdprslaalsNSLRVLNISGNNIDSLEPLAPLRNLEQLDasnnqisdl 157

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462622367  222 --------------SLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQ 261
Cdd:cd21340    158 eelldllsswpslrELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQ 211
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1281-2095 3.77e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.77e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1281 RASKRQSEKEMEELHHN---IDDLLQEkksLECEVEELHRTVQKRQQQKDfidgnVESLMTELEIEKSLKHHEDIVDEIE 1357
Cdd:TIGR02168  171 KERRKETERKLERTRENldrLEDILNE---LERQLKSLERQAEKAERYKE-----LKAELRELELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1358 CIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQ 1437
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1438 ADAKDLEQHKIKQEEILKEINKivaakdsDFQCLSKKKEKLTEELQKLQKDIEMAERNedhhlqvLKESEVLLQAKRAEL 1517
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEE-------KLEELKEELESLEAELEELEAELEELESR-------LEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1518 EKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEA-LRLGETEVTEKCNHIREVKSLLEELSFQKGELNV 1596
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1597 QISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQlENHELQGLKLQHDQRVSELEKTQVAVLEEKLELE 1676
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAIEAALGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1677 nlQQI----SQQQKGEIEWQKQ----------LLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTK 1742
Cdd:TIGR02168  548 --QAVvvenLNAAKKAIAFLKQnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1743 RV---LAAAEENSKMEQSNL--------------------EKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKRE 1799
Cdd:TIGR02168  626 LVvddLDNALELAKKLRPGYrivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1800 AVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1879
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1880 QQEMMFQRLQKERESEESKLEtskvtlkeqqhQLEKELTDQKSKLDQVLSKvlaaeervrtlqeeerwCESLEKTLSQTK 1959
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALD-----------ELRAELTLLNEEAANLRER-----------------LESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1960 RQLSEREQQLVEKSGELLALQKEadsmRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKnlLMANQKDLERRQM 2039
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEALALLRSELEE--LSEELRELESKRS 911

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 2040 EISDAMRTLKSEVKD------EIRTSLKNLNQFLPELPAD-LEAILERNENLEGELESLKENL 2095
Cdd:TIGR02168  912 ELRRELEELREKLAQlelrleGLEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARRRL 974
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 403-1058 8.13e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 8.13e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  403 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLE-----LQMEKQKQEIAGKQKEIKDLQIAIDS 477
Cdd:COG1196    178 ERKLEATEENLERLEDILGELERQLEPLERQAEKAERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  478 LDSKdpkHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT--EGQIAANEALKKDLEGVISG 555
Cdd:COG1196    258 LEAE---LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRelEERLEELEEELAELEEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  556 LQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivamdaENMRKELAELESALQEQHEVNASLQQTQGD 635
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE------EELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  636 LSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQD 715
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  716 DNNLLKQQLKDFQNHLNhvvdglvRPEEVAARVDELRRKLKLGTGEMNIHspsdvlgksladlqkqfseilarskWERDE 795
Cdd:COG1196    489 AAARLLLLLEAEADYEG-------FLEGVKAALLLAGLRGLAGAVAVLIG-------------------------VEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  796 AQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFdkrqhEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEA 875
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF-----LPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  876 DEEKERILAQLRELEKKKKLEDAKSQEQVfgldkelkklkkAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQ 955
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAV------------TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  956 EAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEmektgvgtgansqVLEIEKLNETMERQRTEIARLQNVLDL 1035
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE-------------ELEEEALEEQLEAEREELLEELLEEEE 746

                          650       660
                   ....*....|....*....|...
gi 2462622367 1036 TGSDNKGGFENVLEEIAELRREV 1058
Cdd:COG1196    747 LLEEEALEELPEPPDLEELEREL 769
46 super family cl33686
endonuclease subunit; Provisional
 278-515 1.77e-05

endonuclease subunit; Provisional


The actual alignment was detected with superfamily member PHA02562:

Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.01  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  278 DLEKKMIEtEELKSkQTRFLEEIKNQDKLNKSLKEEAMLQ-KQSCEELKSDLNTKNELYAEIDKaPDESPyiGKSRYKRN 356
Cdd:PHA02562   187 DMKIDHIQ-QQIKT-YNKNIEEQRKKNGENIARKQNKYDElVEEAKTIKAEIEELTDELLNLVM-DIEDP--SAALNKLN 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  357 MFATESyiidSAQAVQIKKMEpdeqlrndHMNLRGHT-PLDTQ-LEDKEKKISAAQTRLSELHDEIEKAEQQIlraTEEF 434
Cdd:PHA02562   262 TAAAKI----KSKIEQFQKVI--------KMYEKGGVcPTCTQqISEGPDRITKIKDKLKELQHSLEKLDTAI---DELE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  435 KQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHshmKAQKSGKEQQLDIMNKQYQQLESRLD 514
Cdd:PHA02562   327 EIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDN---AEELAKLQDELDKIVKTKSELVKEKY 403


                   .
gi 2462622367  515 E 515
Cdd:PHA02562   404 H 404
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-261 2.33e-23

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 100.63  E-value: 2.33e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   89 KKLTKQDNLALIKSL-------NlslskdggkKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISK 161
Cdd:cd21340     12 KNITKIDNLSLCKNLkvlylydN---------KITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISV 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  162 IEGIENMCNLQKLNLAGNEIEhipvwLGKKL-----------KSLRVLNLKGNKISSLQDISKLKPLQDLI--------- 221
Cdd:cd21340     83 VEGLENLTNLEELHIENQRLP-----PGEKLtfdprslaalsNSLRVLNISGNNIDSLEPLAPLRNLEQLDasnnqisdl 157

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462622367  222 --------------SLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQ 261
Cdd:cd21340    158 eelldllsswpslrELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQ 211
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1281-2095 3.77e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.77e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1281 RASKRQSEKEMEELHHN---IDDLLQEkksLECEVEELHRTVQKRQQQKDfidgnVESLMTELEIEKSLKHHEDIVDEIE 1357
Cdd:TIGR02168  171 KERRKETERKLERTRENldrLEDILNE---LERQLKSLERQAEKAERYKE-----LKAELRELELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1358 CIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQ 1437
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1438 ADAKDLEQHKIKQEEILKEINKivaakdsDFQCLSKKKEKLTEELQKLQKDIEMAERNedhhlqvLKESEVLLQAKRAEL 1517
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEE-------KLEELKEELESLEAELEELEAELEELESR-------LEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1518 EKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEA-LRLGETEVTEKCNHIREVKSLLEELSFQKGELNV 1596
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1597 QISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQlENHELQGLKLQHDQRVSELEKTQVAVLEEKLELE 1676
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAIEAALGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1677 nlQQI----SQQQKGEIEWQKQ----------LLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTK 1742
Cdd:TIGR02168  548 --QAVvvenLNAAKKAIAFLKQnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1743 RV---LAAAEENSKMEQSNL--------------------EKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKRE 1799
Cdd:TIGR02168  626 LVvddLDNALELAKKLRPGYrivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1800 AVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1879
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1880 QQEMMFQRLQKERESEESKLEtskvtlkeqqhQLEKELTDQKSKLDQVLSKvlaaeervrtlqeeerwCESLEKTLSQTK 1959
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALD-----------ELRAELTLLNEEAANLRER-----------------LESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1960 RQLSEREQQLVEKSGELLALQKEadsmRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKnlLMANQKDLERRQM 2039
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEALALLRSELEE--LSEELRELESKRS 911

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 2040 EISDAMRTLKSEVKD------EIRTSLKNLNQFLPELPAD-LEAILERNENLEGELESLKENL 2095
Cdd:TIGR02168  912 ELRRELEELREKLAQlelrleGLEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARRRL 974
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
96-339 7.72e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 97.70  E-value: 7.72e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   96 NLALIKSLNLSlskdgGKKFKYI-ENLEKCVKLEVLNLSYNLIGKI-EKLDKLLKLRELNLSYNKISKI-EGIENMCNLQ 172
Cdd:COG4886    134 NLTNLKELDLS-----NNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLpEPLGNLTNLE 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  173 KLNLAGNEIEHIPVWLGkKLKSLRVLNLKGNKISSLQDISKLKPLQdliSLILVENPVVTLPHYLQFTifHLRSLeSLEG 252
Cdd:COG4886    209 ELDLSGNQLTDLPEPLA-NLTNLETLDLSNNQLTDLPELGNLTNLE---ELDLSNNQLTDLPPLANLT--NLKTL-DLSN 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  253 QPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKN 332
Cdd:COG4886    282 NQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSL 361


                   ....*..
gi 2462622367  333 ELYAEID 339
Cdd:COG4886    362 LLTLLLT 368
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 403-1058 8.13e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 8.13e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  403 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLE-----LQMEKQKQEIAGKQKEIKDLQIAIDS 477
Cdd:COG1196    178 ERKLEATEENLERLEDILGELERQLEPLERQAEKAERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  478 LDSKdpkHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT--EGQIAANEALKKDLEGVISG 555
Cdd:COG1196    258 LEAE---LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRelEERLEELEEELAELEEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  556 LQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivamdaENMRKELAELESALQEQHEVNASLQQTQGD 635
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE------EELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  636 LSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQD 715
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  716 DNNLLKQQLKDFQNHLNhvvdglvRPEEVAARVDELRRKLKLGTGEMNIHspsdvlgksladlqkqfseilarskWERDE 795
Cdd:COG1196    489 AAARLLLLLEAEADYEG-------FLEGVKAALLLAGLRGLAGAVAVLIG-------------------------VEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  796 AQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFdkrqhEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEA 875
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF-----LPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  876 DEEKERILAQLRELEKKKKLEDAKSQEQVfgldkelkklkkAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQ 955
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAV------------TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  956 EAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEmektgvgtgansqVLEIEKLNETMERQRTEIARLQNVLDL 1035
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE-------------ELEEEALEEQLEAEREELLEELLEEEE 746

                          650       660
                   ....*....|....*....|...
gi 2462622367 1036 TGSDNKGGFENVLEEIAELRREV 1058
Cdd:COG1196    747 LLEEEALEELPEPPDLEELEREL 769
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 395-1054 2.38e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.38e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAI--------QLKKEALDLELQMEKQKQEIAGKQK 466
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLeeleaqleELESKLDELAEELAELEEKLEELKE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  467 EIKDLQIAIDSLDSKDPKhshMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALK 546
Cdd:TIGR02168  352 ELESLEAELEELEAELEE---LESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  547 KDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVN 626
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  627 ASLQQTQGDLSAYEAELEARLNLRDaeanqlKEELEKVTRLTQLEQSALQAELEKERQAL----KNALGKAQFSEE---K 699
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDE------GYEAAIEAALGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLdsiK 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  700 EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVL-------- 771
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLvrpggvit 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  772 -GKSLADLQKQFSEI-LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEAR-----MNFDKRQHEARI 844
Cdd:TIGR02168  663 gGSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqisaLRKDLARLEAEV 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  845 QQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEkkKKLEDAKSQEQVFGLDKELKKLKKAvATSDKL 924
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE--AQIEQLKEELKALREALDELRAELT-LLNEEA 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  925 ATAELTIA--KDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQF-RLEMEKTGV 1001
Cdd:TIGR02168  820 ANLRERLEslERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALaLLRSELEEL 899

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 1002 GTGANSQVLEIEKLNETMERQRTEIARLQNVLDLTgsdnKGGFENVLEEIAEL 1054
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1735-1996 1.49e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.49e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 LNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1894
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1895 EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSG 1974
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260
                   ....*....|....*....|..
gi 2462622367 1975 ELLALQKEADSMRADFSLLRNQ 1996
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEA 499
LRR_9 pfam14580
Leucine-rich repeat;
130-279 1.51e-13

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 70.95  E-value: 1.51e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  130 LNLSYNLIGKIEKLDKLL-KLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSL 208
Cdd:pfam14580   24 LDLRGYKIPIIENLGATLdQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQEL 103

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367  209 QDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDL 279
Cdd:pfam14580  104 GDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQAAEKMFRSKQGKQLAKEI 174
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1274-2042 1.35e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 73.61  E-value: 1.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1274 KREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHH--ED 1351
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDmlED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1352 IVDEIECIEKTLLKRRSELREADRLLAEAEsELSCTKEKTKNAVEkfTDAKRSLLQTESDA-EELERRAQETAVNLVKAD 1430
Cdd:pfam15921  168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFE-EASGKKIYEHDSMS--TMHFRSLGSAISKIlRELDTEISYLKGRIFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1431 QQLRSLQADAKD-----LEQHKIKQEEILKEinkivaaKDSDFQCLSKKKEKLTEELQKLQKDIEMAERnedhhlQVLKE 1505
Cdd:pfam15921  245 DQLEALKSESQNkiellLQQHQDRIEQLISE-------HEVEITGLTEKASSARSQANSIQSQLEIIQE------QARNQ 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1506 SEVLLQakraELEKLKSQVTSQQQEMAVLDRQLGHKKEELhllQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLE 1585
Cdd:pfam15921  312 NSMYMR----QLSDLESTVSQLRSELREAKRMYEDKIEEL---EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLA 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1586 ELSFQKGELNVQiserKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQ 1665
Cdd:pfam15921  385 DLHKREKELSLE----KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESL 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1666 VAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRvl 1745
Cdd:pfam15921  461 EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN-- 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1746 aaAEENSKMEQSNLEKLELN-------VRKLQQELDQLNR--------------DKLSLHNDISAMQQQLQE----KREA 1800
Cdd:pfam15921  539 --EGDHLRNVQTECEALKLQmaekdkvIEILRQQIENMTQlvgqhgrtagamqvEKAQLEKEINDRRLELQEfkilKDKK 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1801 VNSLQEELANVQDhLNLAKQDLLHTTkhqdvllSEQTRLQKDISE----WANRFEDCQKEEETKQQQLQVLQNEIEEnkl 1876
Cdd:pfam15921  617 DAKIRELEARVSD-LELEKVKLVNAG-------SERLRAVKDIKQerdqLLNEVKTSRNELNSLSEDYEVLKRNFRN--- 685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1877 KLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ----------LEKELTDQKSKLDQVLSKVLAAEERVRTLQEEER 1946
Cdd:pfam15921  686 KSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH 765

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1947 WCESLEKTLSQtkrqlsereqqlveksgELLALQKEADSMRADFSLLRNQfltERKKAEKqVASLKEALKiqrsqlEKNL 2026
Cdd:pfam15921  766 FLKEEKNKLSQ-----------------ELSTVATEKNKMAGELEVLRSQ---ERRLKEK-VANMEVALD------KASL 818

                          810
                   ....*....|....*.
gi 2462622367 2027 LMANQKDLERRQMEIS 2042
Cdd:pfam15921  819 QFAECQDIIQRQEQES 834
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 379-1073 4.31e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 68.71  E-value: 4.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  379 DEQLRNDHMNLRGHTpldTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQ--MEK 456
Cdd:pfam12128  229 DIQAIAGIMKIRPEF---TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKekRDE 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  457 QKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQldimnkQYQQLESRLDEILSRIAKETEEIKDLEEQLTE 536
Cdd:pfam12128  306 LNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE------QLPSWQSELENLEERLKALTGKHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  537 GQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKL---------------RDEKETLLQRLTEVEQERDQLEIV 601
Cdd:pfam12128  380 RRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALeselreqleagklefNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  602 AMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEA---ELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAE 678
Cdd:pfam12128  460 PELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKrrdQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  679 LEKERQALKNALGKAQFSEekeqensELHAKLKHLQDDNNLLKQQLKDFQNHLNhvVDGLVRPEEVAARvDELRRKLklg 758
Cdd:pfam12128  540 LRKEAPDWEQSIGKVISPE-------LLHRTDLDPEVWDGSVGGELNLYGVKLD--LKRIDVPEWAASE-EELRERL--- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  759 tgemnihspsDVLGKSL---ADLQKQFSEILARSKWERDEAQVRE---RKLQEEMALQQEKLATGQEEFRQACERALEAR 832
Cdd:pfam12128  607 ----------DKAEEALqsaREKQAAAEEQLVQANGELEKASREEtfaRTALKNARLDLRRLFDEKQSEKDKKNKALAER 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  833 mnfdKRQHEARIQQMENEIHYLQENLKSMEEIQgltDLQLQEADEEKeriLAQLRELEKKKKLEDAKSQEQVFGLDKELK 912
Cdd:pfam12128  677 ----KDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREARTEK---QAYWQVVEGALDAQLALLKAAIAARRSGAK 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  913 KLKKAVATS-----DKLATAELTIAK--DQLKSLHGTVMKINQERAEELQ----EAERFSRKAAQAARDLTRAEAEIELL 981
Cdd:pfam12128  747 AELKALETWykrdlASLGVDPDVIAKlkREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  982 QNLLRQKGEQFRLEMEKTGVGTGANSQVLeiEKLNETMERQRTEIARLQNV-LDLTGSDNKGGFENVLEEIAELRREVSY 1060
Cdd:pfam12128  827 QQQLARLIADTKLRRAKLEMERKASEKQQ--VRLSENLRGLRCEMSKLATLkEDANSEQAQGSIGERLAQLEDLKLKRDY 904

                          730
                   ....*....|...
gi 2462622367 1061 QNDYISSMADPFK 1073
Cdd:pfam12128  905 LSESVKKYVEHFK 917
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
395-1020 8.20e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 67.76  E-value: 8.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKK-----ISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQlkkealdlelqmekqkqEIAGKQKEIK 469
Cdd:PRK02224   192 LKAQIEEKEEKdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVLE-----------------EHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  470 DLQIAIDSLDSKdpkhshmkaqKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIkdleeQLTEGQIAANEALKKDL 549
Cdd:PRK02224   255 TLEAEIEDLRET----------IAETEREREELAEEVRDLRERLEELEEERDDLLAEA-----GLDDADAEAVEARREEL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  550 EGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivaMDAENMRKELAELESALQEQHEVNASL 629
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE---SELEEAREAVEDRREEIEELEEEIEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  630 QQTQGDLSAYEAELEARLNLRDAEANQLKEELekvtrltqleqsalqAELEKERQALKNALGKAQ--------------- 694
Cdd:PRK02224   397 RERFGDAPVDLGNAEDFLEELREERDELRERE---------------AELEATLRTARERVEEAEalleagkcpecgqpv 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  695 -------FSEEKEQENSELHAKLkhlqddnnllkQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSP 767
Cdd:PRK02224   462 egsphveTIEEDRERVEELEAEL-----------EDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRE 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  768 S-DVLGKSLADLQKQFSEILARSKWERDEAQvrerKLQEEMALQQEKLATGQEEfRQACERALEARMNFDKRQheARIQQ 846
Cdd:PRK02224   531 TiEEKRERAEELRERAAELEAEAEEKREAAA----EAEEEAEEAREEVAELNSK-LAELKERIESLERIRTLL--AAIAD 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  847 MENEIHYLQENLKSMEEIQgltdlqlqeaDEEKERiLAQLRelEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKlAT 926
Cdd:PRK02224   604 AEDEIERLREKREALAELN----------DERRER-LAEKR--ERKRELEAEFDEARIEEAREDKERAEEYLEQVEE-KL 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  927 AELTIAKDQLKSLHGTVmKINQERAEELQEaerfsRKAAQAAR--DLTRAEAEIELLQNLLRqkgeQFRLEMEKTGVGTg 1004
Cdd:PRK02224   670 DELREERDDLQAEIGAV-ENELEELEELRE-----RREALENRveALEALYDEAEELESMYG----DLRAELRQRNVET- 738

                          650
                   ....*....|....*.
gi 2462622367 1005 ansqvLEIeKLNETME 1020
Cdd:PRK02224   739 -----LER-MLNETFD 748
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1553-2095 1.87e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.63  E-value: 1.87e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1553 VQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELnvqiSERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTE 1632
Cdd:PRK03918   185 IKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKL----EKEVKELEELKEEIEELEKELESLEGSKRKLEEK 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1633 LKNILDMLQLENHELQGLKlqhdQRVSELEKTQVAVLEEKLELENLQQIsQQQKGEIEWQKQLLERDKREIERMTAESRA 1712
Cdd:PRK03918   261 IRELEERIEELKKEIEELE----EKVKELKELKEKAEEYIKLSEFYEEY-LDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1713 LQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEEnskMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDIS---A 1789
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE---LERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISkitA 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1790 MQQQLQEKREAVNSLQEELANVQDHLNLAKQDLlhTTKHQDVLLSEQTRLQKDISewanrfedcqKEEETKQQQLQVLQN 1869
Cdd:PRK03918   413 RIGELKKEIKELKKAIEELKKAKGKCPVCGREL--TEEHRKELLEEYTAELKRIE----------KELKEIEEKERKLRK 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1870 EIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQhQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCE 1949
Cdd:PRK03918   481 ELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELE-KKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1950 SLEKTLSQTKRQLSEREQQLVEKSGELLalqKEADSMRADFSLLRNQFLtERKKAEKQVASLKEALKIQRSQLEKNLLMA 2029
Cdd:PRK03918   560 ELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYL-ELKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367 2030 NQ--KDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENL 2095
Cdd:PRK03918   636 AEteKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 641-1561 1.90e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 1.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  641 AELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQA---ELEKERQALKNALGKAQFSEEKEQEN-SELHAKLKHLQDD 716
Cdd:TIGR02168  196 NELERQLKSLERQAEKAERYKELKAELRELELALLVLrleELREELEELQEELKEAEEELEELTAElQELEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  717 NNLLKQQLKDFQNHLNhvvdglvrpeEVAARVDELRRKLKlgtgemnihspsdVLGKSLADLQKQFSEILArskwERDEA 796
Cdd:TIGR02168  276 VSELEEEIEELQKELY----------ALANEISRLEQQKQ-------------ILRERLANLERQLEELEA----QLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  797 QVRERKLQEEMALQQEKLATGQEEFrqACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEAD 876
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEEL--ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  877 EEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKklkkavatsdklatAELTIAKDQLKSLHGTVmkinQERAEELQE 956
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL--------------EELEEELEELQEELERL----EEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  957 AERFSRKAAQAAR-DLTRAEAEIELLQNLLRQKGEQFR------LEMEKTGVGTGANSQVLEIEklnetmERQRTEI--- 1026
Cdd:TIGR02168  469 ELEEAEQALDAAErELAQLQARLDSLERLQENLEGFSEgvkallKNQSGLSGILGVLSELISVD------EGYEAAIeaa 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1027 --ARLQNVLDltgsdnkGGFENVLEEIAELRRevsyqndyissmadpfKRRGYWYFMPPPPSSKVSSHSSQA-TKDSGVG 1103
Cdd:TIGR02168  543 lgGRLQAVVV-------ENLNAAKKAIAFLKQ----------------NELGRVTFLPLDSIKGTEIQGNDReILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1104 LKYSASTPVrkprpgqqdgKEGSQPPPASGYWvyspirsgLHKLFPSRDADSGGDSQEESelddqeeppfvpPPGYMMYT 1183
Cdd:TIGR02168  600 FLGVAKDLV----------KFDPKLRKALSYL--------LGGVLVVDDLDNALELAKKL------------RPGYRIVT 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1184 vlPDGSPVpqgmalyapppplpnnsrplTPGTVVYGpppagapmvyGPPPPNFSIpfipmgvlhcnvpehHNLENEVSRL 1263
Cdd:TIGR02168  650 --LDGDLV--------------------RPGGVITG----------GSAKTNSSI---------------LERRREIEEL 682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1264 edimqhlkskkreerwmraskrqsEKEMEELHHNIDDLLQEKKSLECEVEELhrTVQKRQQQKDFIDGNVESLMTELEIE 1343
Cdd:TIGR02168  683 ------------------------EEKIEELEEKIAELEKALAELRKELEEL--EEELEQLRKELEELSRQISALRKDLA 736

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1344 KSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETA 1423
Cdd:TIGR02168  737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN 816

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1424 VNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVaakdsdfqclskkkEKLTEELQKLQKDIEMAERNEDHHLQVL 1503
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI--------------ESLAAEIEELEELIEELESELEALLNER 882

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367 1504 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQE 1561
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940
46 PHA02562
endonuclease subunit; Provisional
 278-515 1.77e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.01  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  278 DLEKKMIEtEELKSkQTRFLEEIKNQDKLNKSLKEEAMLQ-KQSCEELKSDLNTKNELYAEIDKaPDESPyiGKSRYKRN 356
Cdd:PHA02562   187 DMKIDHIQ-QQIKT-YNKNIEEQRKKNGENIARKQNKYDElVEEAKTIKAEIEELTDELLNLVM-DIEDP--SAALNKLN 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  357 MFATESyiidSAQAVQIKKMEpdeqlrndHMNLRGHT-PLDTQ-LEDKEKKISAAQTRLSELHDEIEKAEQQIlraTEEF 434
Cdd:PHA02562   262 TAAAKI----KSKIEQFQKVI--------KMYEKGGVcPTCTQqISEGPDRITKIKDKLKELQHSLEKLDTAI---DELE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  435 KQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHshmKAQKSGKEQQLDIMNKQYQQLESRLD 514
Cdd:PHA02562   327 EIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDN---AEELAKLQDELDKIVKTKSELVKEKY 403


                   .
gi 2462622367  515 E 515
Cdd:PHA02562   404 H 404
PLN03150 PLN03150
hypothetical protein; Provisional
 145-206 1.82e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.27  E-value: 1.82e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  145 KLLKLRELNLSYNKIskiEG-----IENMCNLQKLNLAGNEIE-HIPVWLGKkLKSLRVLNLKGNKIS 206
Cdd:PLN03150   440 KLRHLQSINLSGNSI---RGnippsLGSITSLEVLDLSYNSFNgSIPESLGQ-LTSLRILNLNGNSLS 503
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-261 2.33e-23

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 100.63  E-value: 2.33e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   89 KKLTKQDNLALIKSL-------NlslskdggkKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISK 161
Cdd:cd21340     12 KNITKIDNLSLCKNLkvlylydN---------KITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISV 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  162 IEGIENMCNLQKLNLAGNEIEhipvwLGKKL-----------KSLRVLNLKGNKISSLQDISKLKPLQDLI--------- 221
Cdd:cd21340     83 VEGLENLTNLEELHIENQRLP-----PGEKLtfdprslaalsNSLRVLNISGNNIDSLEPLAPLRNLEQLDasnnqisdl 157

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462622367  222 --------------SLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQ 261
Cdd:cd21340    158 eelldllsswpslrELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQ 211
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1281-2095 3.77e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.77e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1281 RASKRQSEKEMEELHHN---IDDLLQEkksLECEVEELHRTVQKRQQQKDfidgnVESLMTELEIEKSLKHHEDIVDEIE 1357
Cdd:TIGR02168  171 KERRKETERKLERTRENldrLEDILNE---LERQLKSLERQAEKAERYKE-----LKAELRELELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1358 CIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQ 1437
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1438 ADAKDLEQHKIKQEEILKEINKivaakdsDFQCLSKKKEKLTEELQKLQKDIEMAERNedhhlqvLKESEVLLQAKRAEL 1517
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEE-------KLEELKEELESLEAELEELEAELEELESR-------LEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1518 EKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEA-LRLGETEVTEKCNHIREVKSLLEELSFQKGELNV 1596
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1597 QISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQlENHELQGLKLQHDQRVSELEKTQVAVLEEKLELE 1676
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAIEAALGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1677 nlQQI----SQQQKGEIEWQKQ----------LLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTK 1742
Cdd:TIGR02168  548 --QAVvvenLNAAKKAIAFLKQnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1743 RV---LAAAEENSKMEQSNL--------------------EKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKRE 1799
Cdd:TIGR02168  626 LVvddLDNALELAKKLRPGYrivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1800 AVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1879
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1880 QQEMMFQRLQKERESEESKLEtskvtlkeqqhQLEKELTDQKSKLDQVLSKvlaaeervrtlqeeerwCESLEKTLSQTK 1959
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALD-----------ELRAELTLLNEEAANLRER-----------------LESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1960 RQLSEREQQLVEKSGELLALQKEadsmRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKnlLMANQKDLERRQM 2039
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEALALLRSELEE--LSEELRELESKRS 911

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 2040 EISDAMRTLKSEVKD------EIRTSLKNLNQFLPELPAD-LEAILERNENLEGELESLKENL 2095
Cdd:TIGR02168  912 ELRRELEELREKLAQlelrleGLEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARRRL 974
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
96-339 7.72e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 97.70  E-value: 7.72e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   96 NLALIKSLNLSlskdgGKKFKYI-ENLEKCVKLEVLNLSYNLIGKI-EKLDKLLKLRELNLSYNKISKI-EGIENMCNLQ 172
Cdd:COG4886    134 NLTNLKELDLS-----NNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLpEPLGNLTNLE 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  173 KLNLAGNEIEHIPVWLGkKLKSLRVLNLKGNKISSLQDISKLKPLQdliSLILVENPVVTLPHYLQFTifHLRSLeSLEG 252
Cdd:COG4886    209 ELDLSGNQLTDLPEPLA-NLTNLETLDLSNNQLTDLPELGNLTNLE---ELDLSNNQLTDLPPLANLT--NLKTL-DLSN 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  253 QPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKN 332
Cdd:COG4886    282 NQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSL 361


                   ....*..
gi 2462622367  333 ELYAEID 339
Cdd:COG4886    362 LLTLLLT 368
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 403-1058 8.13e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 8.13e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  403 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLE-----LQMEKQKQEIAGKQKEIKDLQIAIDS 477
Cdd:COG1196    178 ERKLEATEENLERLEDILGELERQLEPLERQAEKAERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  478 LDSKdpkHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT--EGQIAANEALKKDLEGVISG 555
Cdd:COG1196    258 LEAE---LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRelEERLEELEEELAELEEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  556 LQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivamdaENMRKELAELESALQEQHEVNASLQQTQGD 635
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE------EELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  636 LSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQD 715
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  716 DNNLLKQQLKDFQNHLNhvvdglvRPEEVAARVDELRRKLKLGTGEMNIHspsdvlgksladlqkqfseilarskWERDE 795
Cdd:COG1196    489 AAARLLLLLEAEADYEG-------FLEGVKAALLLAGLRGLAGAVAVLIG-------------------------VEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  796 AQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFdkrqhEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEA 875
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF-----LPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  876 DEEKERILAQLRELEKKKKLEDAKSQEQVfgldkelkklkkAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQ 955
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAV------------TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  956 EAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEmektgvgtgansqVLEIEKLNETMERQRTEIARLQNVLDL 1035
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE-------------ELEEEALEEQLEAEREELLEELLEEEE 746

                          650       660
                   ....*....|....*....|...
gi 2462622367 1036 TGSDNKGGFENVLEEIAELRREV 1058
Cdd:COG1196    747 LLEEEALEELPEPPDLEELEREL 769
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1256-2016 3.77e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.12  E-value: 3.77e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVES 1335
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1336 LMTELeiekslkhhEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEEL 1415
Cdd:TIGR02168  314 LERQL---------EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1416 ERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKivAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERN 1495
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1496 EDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD------RQLGHKKEELHLLQG---SMVQAKADLQEALR-- 1564
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvKALLKNQSGLSGILGvlsELISVDEGYEAAIEaa 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1565 LGETE---VTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDML- 1640
Cdd:TIGR02168  543 LGGRLqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLl 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1641 -------QLENHELQGLKLQHDQRVSELEKTQVAVLEEKLelenlqqisqqqKGEIEWQKQLLERdKREIERMTAESRAL 1713
Cdd:TIGR02168  623 ggvlvvdDLDNALELAKKLRPGYRIVTLDGDLVRPGGVIT------------GGSAKTNSSILER-RREIEELEEKIEEL 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1714 QSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQ 1793
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1794 LQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEE 1873
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1874 NKLKLVQQEMMFQRLQKERESEESKLEtskvTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEerwCESLEK 1953
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELE----ALLNERASLEEALALLRSELEELSEELRELESKRSELRRE---LEELRE 922

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462622367 1954 TLSQTKRQLSEREQQLVEKSGELLALQK-EADSMRAdfslLRNQFLTERKKAEKQVASLKEALK 2016
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA----LENKIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 395-993 7.89e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.85  E-value: 7.89e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQlkkealDLELQMEKQKQEIAGKQKEIKDLQIA 474
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE------ELEEELAELEEELEELEEELEELEEE 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  475 IDSLdskdpkhshmkaqksgkEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEgvis 554
Cdd:COG1196    346 LEEA-----------------EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE---- 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  555 glqeylgtIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQhevnaslQQTQG 634
Cdd:COG1196    405 --------LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL-------LAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  635 DLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQ 714
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  715 DDNNLLKQQLKDFQNHLNHVVDGLV--RPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWE 792
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRAtfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  793 RDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQL 872
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  873 QEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATA---ELTIAKDQLKSLhGTVmkiNQE 949
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEElerELERLEREIEAL-GPV---NLL 785

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 2462622367  950 RAEELQEA-ERFSRKAAQAArDLTRAEAEIELL-QNLLRQKGEQFR 993
Cdd:COG1196    786 AIEEYEELeERYDFLSEQRE-DLEEARETLEEAiEEIDRETRERFL 830
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-250 2.44e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.99  E-value: 2.44e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   55 QVEIADENNMLLDYQDHKGADSHAGVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSY 134
Cdd:COG4886     43 LSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSG 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  135 NLIGKI-EKLDKLLKLRELNLSYNKISKI-EGIENMCNLQKLNLAGNEIEHIPVWLGkKLKSLRVLNLKGNKISSLQD-I 211
Cdd:COG4886    123 NQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEpL 201

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2462622367  212 SKLKPLQdliSLILVENPVVTLPHylqfTIFHLRSLESL 250
Cdd:COG4886    202 GNLTNLE---ELDLSGNQLTDLPE----PLANLTNLETL 233
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 395-1054 2.38e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.38e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAI--------QLKKEALDLELQMEKQKQEIAGKQK 466
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLeeleaqleELESKLDELAEELAELEEKLEELKE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  467 EIKDLQIAIDSLDSKDPKhshMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALK 546
Cdd:TIGR02168  352 ELESLEAELEELEAELEE---LESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  547 KDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVN 626
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  627 ASLQQTQGDLSAYEAELEARLNLRDaeanqlKEELEKVTRLTQLEQSALQAELEKERQAL----KNALGKAQFSEE---K 699
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDE------GYEAAIEAALGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLdsiK 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  700 EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVL-------- 771
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLvrpggvit 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  772 -GKSLADLQKQFSEI-LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEAR-----MNFDKRQHEARI 844
Cdd:TIGR02168  663 gGSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqisaLRKDLARLEAEV 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  845 QQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEkkKKLEDAKSQEQVFGLDKELKKLKKAvATSDKL 924
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE--AQIEQLKEELKALREALDELRAELT-LLNEEA 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  925 ATAELTIA--KDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQF-RLEMEKTGV 1001
Cdd:TIGR02168  820 ANLRERLEslERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALaLLRSELEEL 899

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 1002 GTGANSQVLEIEKLNETMERQRTEIARLQNVLDLTgsdnKGGFENVLEEIAEL 1054
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 390-888 2.14e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 2.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  390 RGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEAL-DLELQMEKQKQEIAGKQKEI 468
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELaEAEEALLEAEAELAEAEEEL 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  469 KDLQIAIDSLdskdpkhshmkaqksgkEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKD 548
Cdd:COG1196    382 EELAEELLEA-----------------LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  549 LEgvisgLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNAS 628
Cdd:COG1196    445 EE-----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  629 LQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHA 708
Cdd:COG1196    520 RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  709 KLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPsdvlGKSLADLQKQFSEILAR 788
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA----GGSLTGGSRRELLAALL 675

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  789 SKwERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLT 868
Cdd:COG1196    676 EA-EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          490       500
                   ....*....|....*....|
gi 2462622367  869 DLQLQEADEEKERILAQLRE 888
Cdd:COG1196    755 ELPEPPDLEELERELERLER 774
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 444-756 2.78e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 2.78e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  444 KKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKhshMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKE 523
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ---LRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  524 TEEIKDLEEQLTE--GQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIV 601
Cdd:TIGR02168  753 SKELTELEAEIEEleERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  602 AMDAENMRKELAE-LESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEanqlkEELEKVTRLTQLEQSALQAELE 680
Cdd:TIGR02168  833 IAATERRLEDLEEqIEELSEDIESLAAEIEELEELIEELESELEALLNERASL-----EEALALLRSELEELSEELRELE 907

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367  681 KERQALKNALGKAQFSEEKEQEN-SELHAKLKHLQDdnNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLK 756
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRlEGLEVRIDNLQE--RLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1735-1996 1.49e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.49e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 LNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1894
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1895 EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSG 1974
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260
                   ....*....|....*....|..
gi 2462622367 1975 ELLALQKEADSMRADFSLLRNQ 1996
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEA 499
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1679-2016 4.67e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.67e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1679 QQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSN 1758
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1759 LEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTR 1838
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1839 LQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQemmfQRLQKERESEESKLETSKVTLKEQQHQLEKELT 1918
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE----EEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1919 DQKSKLDQVLSKVLAAEERVRTLQEEErwcESLEKTLSQTKRQLSEREQQLVEKSGELLA---LQKEADSMRADFSLLRN 1995
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAE---ADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveAAYEAALEAALAAALQN 550

                          330       340
                   ....*....|....*....|.
gi 2462622367 1996 QFLTERKKAEKQVASLKEALK 2016
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKA 571
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1509-2093 5.40e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 5.40e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1509 LLQAKRAELEKLKSQVtSQQQEMAVLDRQLGHKKEELHLLQGSMVQAK-ADLQEALRLGETEVTEKCNHIREVKSLLEEL 1587
Cdd:COG1196    194 ILGELERQLEPLERQA-EKAERYRELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1588 SFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQmskhKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1667
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEER----RRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1668 VLEEKLELENLQQISQQQKGEIEwqKQLLERDKREIERMTAESRALQSCVECLSKEKEdLQEKCDIWEKKLAQTKRVLAA 1747
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAE--AELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1748 AEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELA-NVQDHLNLAKQDLLHTT 1826
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAeAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1827 KHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQ--LQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 1904
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAalAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1905 TLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEAD 1984
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1985 SMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLN 2064
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580
                   ....*....|....*....|....*....
gi 2462622367 2065 QFLPELPADLEAILERNENLEGELESLKE 2093
Cdd:COG1196    746 ELLEEEALEELPEPPDLEELERELERLER 774
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1471-2141 7.63e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 7.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1471 LSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKeseVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQG 1550
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKAELRELELALLV---LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1551 SMVQAKADLQEAlrlgETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQvvlrQMSKHK 1630
Cdd:TIGR02168  275 EVSELEEEIEEL----QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA----ELEEKL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1631 TELKNILDMLQLENHELQGLKLQHDQRVSELEKtqvAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAES 1710
Cdd:TIGR02168  347 EELKEELESLEAELEELEAELEELESRLEELEE---QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1711 RALQScvECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENskmeqsnLEKLELNVRKLQQELDQLNRDKLSLHNDISAM 1790
Cdd:TIGR02168  424 EELLK--KLEEAELKELQAELEELEEELEELQEELERLEEA-------LEELREELEEAEQALDAAERELAQLQARLDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1791 QQQLQEKREAVNSLQEELAN------------------------------------VQDHLNLAKQDLLHTTKHQDVLLS 1834
Cdd:TIGR02168  495 ERLQENLEGFSEGVKALLKNqsglsgilgvlselisvdegyeaaieaalggrlqavVVENLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1835 -------EQTRLQKDISEWANRFEDCQ---KEEETKQQQLQVLQN------------EIEENKLKLVQQEMMF------- 1885
Cdd:TIGR02168  575 flpldsiKGTEIQGNDREILKNIEGFLgvaKDLVKFDPKLRKALSyllggvlvvddlDNALELAKKLRPGYRIvtldgdl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1886 ----------------QRLQKERESEEskLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCE 1949
Cdd:TIGR02168  655 vrpggvitggsaktnsSILERRREIEE--LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1950 SLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEknllmA 2029
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD-----E 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2030 NQKDLERRQMEISDAMRTLKSEVKDEIRTSlknlnQFLPELPADLEAILERNENLEGELESLKENLpftmnegpfeEKLN 2109
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATE-----RRLEDLEEQIEELSEDIESLAAEIEELEELI----------EELE 872

                          730       740       750
                   ....*....|....*....|....*....|..
gi 2462622367 2110 FSQVHIMDEHWRGEALREKLRHREDRLKAQLR 2141
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELR 904
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1254-1918 9.50e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 9.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1254 HNLENEVSRLEDIMQHLKSKKREerwMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNV 1333
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDE---LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1334 ESLmtELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAE-SELSCTKEKTKNAVEKFTDAKRSLLQTESDA 1412
Cdd:TIGR02168  389 AQL--ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEEL 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1413 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLS------KKKEK--------- 1477
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSelisvdEGYEAaieaalggr 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1478 ----LTEELQKLQKDIEMAERNEDHHLQVLkeseVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELH-----LL 1548
Cdd:TIGR02168  547 lqavVVENLNAAKKAIAFLKQNELGRVTFL----PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyLL 622

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1549 QGSMV----QAKADLQEALRLGETEVTEKCNHIREVKSlleeLSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLR 1624
Cdd:TIGR02168  623 GGVLVvddlDNALELAKKLRPGYRIVTLDGDLVRPGGV----ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK 698

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1625 QMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIE 1704
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1705 RMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLH 1784
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1785 NDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEwanrfedCQKEEETKQQQL 1864
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE-------LREKLAQLELRL 931

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1865 QVLQNEIEENKLKL-VQQEMMFQrlqkERESEESKLETSKVTLKEQQHQLEKELT 1918
Cdd:TIGR02168  932 EGLEVRIDNLQERLsEEYSLTLE----EAEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1288-2117 1.02e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.42  E-value: 1.02e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1288 EKEMEELHHNIDDLLQEKKSLECEVEELHR--TVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLK 1365
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1366 RRSELREADRLLAEAESELSCTKEKTKNAV-EKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLE 1444
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1445 QhkikqeeilkeinkivaakdsDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQV 1524
Cdd:TIGR02169  343 R---------------------EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1525 TSQQQEMavldRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQ 1604
Cdd:TIGR02169  402 NELKREL----DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1605 LTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVleEKLELENLQQISQQ 1684
Cdd:TIGR02169  478 YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI--EVAAGNRLNNVVVE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1685 QKGEIEWQKQLLERdkREIERMT----AESRALQSCVECLSKEKE-----DLQEKCDIWEKKLAQTKRvlaaaeenSKME 1755
Cdd:TIGR02169  556 DDAVAKEAIELLKR--RKAGRATflplNKMRDERRDLSILSEDGVigfavDLVEFDPKYEPAFKYVFG--------DTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1756 QSNLE---KLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREavnslQEELANVQDHLNLAKQDLlhttkhqDVL 1832
Cdd:TIGR02169  626 VEDIEaarRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSE-----PAELQRLRERLEGLKREL-------SSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1833 LSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQ-- 1910
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEed 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1911 -HQLEKELTDQKSKLDQvlskvlaaeERVRTLQEEERwceSLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAD 1989
Cdd:TIGR02169  774 lHKLEEALNDLEARLSH---------SRIPEIQAELS---KLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1990 FSLLRNQFLTERKKAE---KQVASLKEALKiqRSQLEKNLLMANQKDLERRQMEISDAMRTLKSEvKDEIRTSLKNLNQF 2066
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIEnlnGKKEELEEELE--ELEAALRDLESRLGDLKKERDELEAQLRELERK-IEELEAQIEKKRKR 918

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 2067 LPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMD 2117
Cdd:TIGR02169  919 LSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1284-1873 1.07e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.07e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1284 KRQSEKEMEELHHN---IDDLLQEK----KSLE--CEVEELHRTVQKRQQQKDfidgnveSLMTELEIEKSLKHHEDIVD 1354
Cdd:COG1196    174 KEEAERKLEATEENlerLEDILGELerqlEPLErqAEKAERYRELKEELKELE-------AELLLLKLRELEAELEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1355 EIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLR 1434
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1435 SLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKR 1514
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1515 AELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGEL 1594
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1595 NVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILD----------------MLQLENHE--------LQGL 1650
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaayeaaleaalaaALQNIVVEddevaaaaIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1651 KLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEk 1730
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR- 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1731 cdiWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELAN 1810
Cdd:COG1196    646 ---LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 1811 VQDHLNLAKQDLLHttkhqdvLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEE 1873
Cdd:COG1196    723 EEALEEQLEAEREE-------LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
LRR_9 pfam14580
Leucine-rich repeat;
130-279 1.51e-13

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 70.95  E-value: 1.51e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  130 LNLSYNLIGKIEKLDKLL-KLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSL 208
Cdd:pfam14580   24 LDLRGYKIPIIENLGATLdQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQEL 103

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367  209 QDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDL 279
Cdd:pfam14580  104 GDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQAAEKMFRSKQGKQLAKEI 174
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1412-2011 3.14e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 3.14e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1412 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEM 1491
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1492 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLgetevt 1571
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE------ 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1572 ekcnhIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK 1651
Cdd:COG1196    374 -----LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1652 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRAlqscveclSKEKEDLQEKC 1731
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG--------VKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1732 DIWEKK--LAQTKRVLAAAEENSkMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELA 1809
Cdd:COG1196    521 GLAGAVavLIGVEAAYEAALEAA-LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1810 NVQDHLNLAKQDLLHTTKHQDVLLSEqtrlqkdiSEWANRFEDCQKEEETKQQQLQVLQNEIEEnklkLVQQEMMFQRLQ 1889
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGR--------TLVAARLEAALRRAVTLAGRLREVTLEGEG----GSAGGSLTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1890 KERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEErwceslEKTLSQTKRQLSEREQQL 1969
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEE------EALEEQLEAEREELLEEL 741

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2462622367 1970 VEKSGELLALQKEADSMRADFSLLRnqflTERKKAEKQVASL 2011
Cdd:COG1196    742 LEEEELLEEEALEELPEPPDLEELE----RELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 518-898 5.23e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 5.23e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  518 SRIAKETEEIKDLEEQLTEGQIAANEALKK--DLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQER 595
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKEleELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  596 DQLEIVAMDAENMRKEL-AELESALQEQHEVNASLQQTQGDLSAYEA---ELEARLNLRDAEANQLKEELEKVT-RLTQL 670
Cdd:TIGR02168  757 TELEAEIEELEERLEEAeEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLErRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  671 EQSALQAELEKERQALKNALGKAQFSEEKEQENsELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLvrpEEVAARVDE 750
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIE-ELESELEALLNERASLEEALALLRSELEELSEEL---RELESKRSE 912

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  751 LRRKLKLgtgemnihspsdvlgksladLQKQFSEILARskweRDEAQVRERKLQEEMALQQEKLATGQEEfrqaceraLE 830
Cdd:TIGR02168  913 LRRELEE--------------------LREKLAQLELR----LEGLEVRIDNLQERLSEEYSLTLEEAEA--------LE 960

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  831 ARMNFDKRQHEARIQQMENEIHYLQE-NLKSMEEiqgltdlqLQEADEEKERILAQLRELEK-KKKLEDA 898
Cdd:TIGR02168  961 NKIEDDEEEARRRLKRLENKIKELGPvNLAAIEE--------YEELKERYDFLTAQKEDLTEaKETLEEA 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 270-1068 7.71e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 7.71e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  270 EEVERLERDLEKKMIETEELKSKQTRFLEEIknqdklnkslkEEAMLQKQSCEELKSDLNTK-NELYAEIDKapdespyi 348
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKL-----------EELRLEVSELEEEIEELQKElYALANEISR-------- 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  349 gksrykrnmfatesyiidsaqaVQIKKMEPDEQLRNDHMNLRghtPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQIL 428
Cdd:TIGR02168  300 ----------------------LEQQKQILRERLANLERQLE---ELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  429 RATEEFKQLEEAIQ-LKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSkdpkhshmkaqksgkeqqldimnkQYQ 507
Cdd:TIGR02168  355 SLEAELEELEAELEeLESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEA------------------------RLE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  508 QLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQR 587
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  588 LTEVEQERDQLEIVAMDAENM---RKELAELESALQEQHEVNASLQQtqgdlsAYEAELEARLNL---------RDAEAN 655
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALlknQSGLSGILGVLSELISVDEGYEA------AIEAALGGRLQAvvvenlnaaKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  656 QLKEELEKVTRLtQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKL----------KHLQDDNNLLKQQLK 725
Cdd:TIGR02168  565 LKQNELGRVTFL-PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALsyllggvlvvDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  726 DFqnhLNHVVDG-LVRPE---------------EVAARVDELRRKLKLGTGEMNIhspsdvLGKSLADLQKQFSEILArs 789
Cdd:TIGR02168  644 GY---RIVTLDGdLVRPGgvitggsaktnssilERRREIEELEEKIEELEEKIAE------LEKALAELRKELEELEE-- 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  790 kwERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERAleARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTD 869
Cdd:TIGR02168  713 --ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI--AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  870 LQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLAtAELTIAKDQLKSLHGTVMKINQE 949
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE-EQIEELSEDIESLAAEIEELEEL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  950 RAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFR-LEMEKTGVGTGANSQVLEIEKLNETMERQrteIAR 1028
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSeLRRELEELREKLAQLELRLEGLEVRIDNL---QER 944

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 2462622367 1029 LQNVLDLTGSDNKGGFENVLEEIAELRREVSYQNDYISSM 1068
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
403-995 9.93e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 74.18  E-value: 9.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  403 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAG-----KQKEIKDLQIAIDS 477
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAAlrlwfAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  478 LDskdpkhshmkAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAK-ETEEIKDLEEqltegQIAANEALKKDLEGVISGL 556
Cdd:COG4913    300 LR----------AELARLEAELERLEARLDALREELDELEAQIRGnGGDRLEQLER-----EIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  557 QEYLGTIKGQATQAQNE----CRKLRDEKETLLQRLTEVEQERDQLEIvamDAENMRKELAELESALqeqhevnASLQQT 632
Cdd:COG4913    365 EALLAALGLPLPASAEEfaalRAEAAALLEALEEELEALEEALAEAEA---ALRDLRRELRELEAEI-------ASLERR 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  633 QGDLSAYE----AELEARLNLRDAEAN------QLKEE-------LEKV---TRLTQLeqsalqAELEKERQALK--NAL 690
Cdd:COG4913    435 KSNIPARLlalrDALAEALGLDEAELPfvgeliEVRPEeerwrgaIERVlggFALTLL------VPPEHYAAALRwvNRL 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  691 ---GKAQFSEEKEQENSELHAKLkhlqDDNNLL-KQQLKD--FQNHLNHVvdgLVRPEEVA--ARVDELRR--------- 753
Cdd:COG4913    509 hlrGRLVYERVRTGLPDPERPRL----DPDSLAgKLDFKPhpFRAWLEAE---LGRRFDYVcvDSPEELRRhpraitrag 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  754 --KLKLGTGEMNIHSPSD---VLGKS----LADLQKQfseiLARSKWERDEAQVRERKLQEEMALQQEKlatgqeefRQA 824
Cdd:COG4913    582 qvKGNGTRHEKDDRRRIRsryVLGFDnrakLAALEAE----LAELEEELAEAEERLEALEAELDALQER--------REA 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  825 CERALEARMNF-DKRQHEARIQQMENEihyLQENLKSMEEIQGLTDlQLQEADEEKERILAQLRELEKK-----KKLEDA 898
Cdd:COG4913    650 LQRLAEYSWDEiDVASAEREIAELEAE---LERLDASSDDLAALEE-QLEELEAELEELEEELDELKGEigrleKELEQA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  899 KSQEQvfgldkelkklkkavATSDKLATAELTIAKDQLKSLhgtvmkinQERAEELQEAERFSRKAAQAARDLTRAEAEI 978
Cdd:COG4913    726 EEELD---------------ELQDRLEAAEDLARLELRALL--------EERFAAALGDAVERELRENLEERIDALRARL 782

                          650
                   ....*....|....*..
gi 2462622367  979 ELLQNLLRQKGEQFRLE 995
Cdd:COG4913    783 NRAEEELERAMRAFNRE 799
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1285-1969 1.03e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 1.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1285 RQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKhhEDIVDEIECIEKTLL 1364
Cdd:TIGR02169  290 LRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR--DKLTEEYAELKEELE 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1365 KRRSELREADRLLAEaeselscTKEKTKNAVEKFTDAKRSLlqtesdaEELERRAQETAVNLVKADQQLRSLQADAKDLE 1444
Cdd:TIGR02169  368 DLRAELEEVDKEFAE-------TRDELKDYREKLEKLKREI-------NELKRELDRLQEELQRLSEELADLNAAIAGIE 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1445 QHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQV 1524
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1525 T---SQQQEMAVLDRQLGHKKEELHL---------LQGSMVQAKADLQEALRLGETEVTEKC-----NHIREVKSLLEEL 1587
Cdd:TIGR02169  514 EvlkASIQGVHGTVAQLGSVGERYATaievaagnrLNNVVVEDDAVAKEAIELLKRRKAGRAtflplNKMRDERRDLSIL 593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1588 SfQKGELN-----VQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKtelknildMLQLENHELQ--------GLKLQH 1654
Cdd:TIGR02169  594 S-EDGVIGfavdlVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYR--------MVTLEGELFEksgamtggSRAPRG 664

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1655 DQRVSELEKTQVAVLEEKLELENLQQISQQQkgEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIW 1734
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLEGLKRELSSLQS--ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLslhndisamQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS---------HSRIPEIQAELSKLEEEVSRIEAR 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 LNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERE- 1893
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDe 893

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367 1894 --SEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKtLSQTKRQLSEREQQL 1969
Cdd:TIGR02169  894 leAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRAL 970
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1274-2042 1.35e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 73.61  E-value: 1.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1274 KREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHH--ED 1351
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDmlED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1352 IVDEIECIEKTLLKRRSELREADRLLAEAEsELSCTKEKTKNAVEkfTDAKRSLLQTESDA-EELERRAQETAVNLVKAD 1430
Cdd:pfam15921  168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFE-EASGKKIYEHDSMS--TMHFRSLGSAISKIlRELDTEISYLKGRIFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1431 QQLRSLQADAKD-----LEQHKIKQEEILKEinkivaaKDSDFQCLSKKKEKLTEELQKLQKDIEMAERnedhhlQVLKE 1505
Cdd:pfam15921  245 DQLEALKSESQNkiellLQQHQDRIEQLISE-------HEVEITGLTEKASSARSQANSIQSQLEIIQE------QARNQ 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1506 SEVLLQakraELEKLKSQVTSQQQEMAVLDRQLGHKKEELhllQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLE 1585
Cdd:pfam15921  312 NSMYMR----QLSDLESTVSQLRSELREAKRMYEDKIEEL---EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLA 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1586 ELSFQKGELNVQiserKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQ 1665
Cdd:pfam15921  385 DLHKREKELSLE----KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESL 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1666 VAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRvl 1745
Cdd:pfam15921  461 EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN-- 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1746 aaAEENSKMEQSNLEKLELN-------VRKLQQELDQLNR--------------DKLSLHNDISAMQQQLQE----KREA 1800
Cdd:pfam15921  539 --EGDHLRNVQTECEALKLQmaekdkvIEILRQQIENMTQlvgqhgrtagamqvEKAQLEKEINDRRLELQEfkilKDKK 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1801 VNSLQEELANVQDhLNLAKQDLLHTTkhqdvllSEQTRLQKDISE----WANRFEDCQKEEETKQQQLQVLQNEIEEnkl 1876
Cdd:pfam15921  617 DAKIRELEARVSD-LELEKVKLVNAG-------SERLRAVKDIKQerdqLLNEVKTSRNELNSLSEDYEVLKRNFRN--- 685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1877 KLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ----------LEKELTDQKSKLDQVLSKVLAAEERVRTLQEEER 1946
Cdd:pfam15921  686 KSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH 765

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1947 WCESLEKTLSQtkrqlsereqqlveksgELLALQKEADSMRADFSLLRNQfltERKKAEKqVASLKEALKiqrsqlEKNL 2026
Cdd:pfam15921  766 FLKEEKNKLSQ-----------------ELSTVATEKNKMAGELEVLRSQ---ERRLKEK-VANMEVALD------KASL 818

                          810
                   ....*....|....*.
gi 2462622367 2027 LMANQKDLERRQMEIS 2042
Cdd:pfam15921  819 QFAECQDIIQRQEQES 834
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 245-894 1.99e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  245 RSLESLEGQPVTTQDRQEAFERfsleEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEEL 324
Cdd:TIGR02169  294 EKIGELEAEIASLERSIAEKER----ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  325 KSDLNTKNELYAEI-DKAPDESPYIGKSRYKRNMFATEsyiIDSAQAVQIKKMEPDEQLRNDHMNLRG-HTPLDTQLEDK 402
Cdd:TIGR02169  370 RAELEEVDKEFAETrDELKDYREKLEKLKREINELKRE---LDRLQEELQRLSEELADLNAAIAGIEAkINELEEEKEDK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  403 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDlelQMEKQKQEIAGKQKEIKDLQIAIDS----- 477
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA---EAEAQARASEERVRGGRAVEEVLKAsiqgv 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  478 ------LDSKDPKHS---------------------------HMKAQKSGKEQQLDIMN-KQYQQLESRLDE-------- 515
Cdd:TIGR02169  524 hgtvaqLGSVGERYAtaievaagnrlnnvvveddavakeaieLLKRRKAGRATFLPLNKmRDERRDLSILSEdgvigfav 603

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  516 -----------ILSRIAKETEEIKDLEEQLTEGQIAANEALKKDL---EGVISG-------LQEYLGTIKGQATQAQNEC 574
Cdd:TIGR02169  604 dlvefdpkyepAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELfekSGAMTGgsraprgGILFSRSEPAELQRLRERL 683

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  575 RKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKEL-AELESALQEQHEVNASLQQTQGDLSAYE----------AEL 643
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERLEELEEDLSSLEqeienvkselKEL 763

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  644 EARLNLRDAEANQLKEELEKVTRLTQLEQ----SALQAELEKERQALKNALGKAQFSEEKEQENSE-LHAKLKHLQDDNN 718
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLEARLSHSRipeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEyLEKEIQELQEQRI 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  719 LLKQQLKDFQNHLNhvvDGLVRPEEVAARVDELRRKLK-LGTGEMNIHSPSDVLGKSLADLQKQFSEIlarsKWERDEAQ 797
Cdd:TIGR02169  844 DLKEQIKSIEKEIE---NLNGKKEELEEELEELEAALRdLESRLGDLKKERDELEAQLRELERKIEEL----EAQIEKKR 916

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  798 VRERKLQEEMALQQEKLATGQEEFRQACEralEARMNFDKRQHEARIQQMENEIHYLQE-NLKSMEE----IQGLTDLQL 872
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEE---IPEEELSLEDVQAELQRVEEEIRALEPvNMLAIQEyeevLKRLDELKE 993

                          730       740
                   ....*....|....*....|....
gi 2462622367  873 QEA--DEEKERILAQLRELEKKKK 894
Cdd:TIGR02169  994 KRAklEEERKAILERIEEYEKKKR 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 255-979 2.35e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  255 VTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDL----NT 330
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELeeleSR 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  331 KNELYAEIDKAPDESPYIGKSRYK-RNMFAT-ESYIIDSAQAVQIKKMEPDEQLRNDHMN-----LRGHTPLDTQLEDKE 403
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASlNNEIERlEARLERLEDRRERLQQEIEELLKKLEEAelkelQAELEELEEELEELQ 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  404 KKISAAQTRLSELHDEIEKAEQQILRATEEFKQLE------EAIQLKKEALDLEL-QMEKQKQEIAGKQKEIKDL----- 471
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVkALLKNQSGLSGILGVLSELisvde 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  472 ---------------QIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTE 536
Cdd:TIGR02168  534 gyeaaieaalggrlqAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  537 GQIA----------------ANEALKK-DLEGVISGLQEYLGTIKGQATQAQNEcrklrdEKETLLQRLTEVEQERDQLE 599
Cdd:TIGR02168  614 LRKAlsyllggvlvvddldnALELAKKlRPGYRIVTLDGDLVRPGGVITGGSAK------TNSSILERRREIEELEEKIE 687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  600 IVAMDAENMRKELAELESALQEqhevnasLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALqAEL 679
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEE-------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL-TEL 759

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  680 EKERQALKNALGKAQFS-EEKEQENSELHAKLKHLQDDNNLLKQQLKDFQnhlnhvvdglvrpeevaARVDELRRKL-KL 757
Cdd:TIGR02168  760 EAEIEELEERLEEAEEElAEAEAEIEELEAQIEQLKEELKALREALDELR-----------------AELTLLNEEAaNL 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  758 GTGEMNIHSPSDVLGKSLADLQKQF---SEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQAceralearmN 834
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL---------R 893

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  835 FDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRElEKKKKLEDAKSQEQvfgldkelkkl 914
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALEN----------- 961

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367  915 kkAVATSDKLATAELTIAKDQLKSLhGTVmkiNQERAEELQE-AERFSRKAAQAArDLTRAEAEIE 979
Cdd:TIGR02168  962 --KIEDDEEEARRRLKRLENKIKEL-GPV---NLAAIEEYEElKERYDFLTAQKE-DLTEAKETLE 1020
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 258-756 2.45e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 2.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  258 QDRQEAFERfSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELYAE 337
Cdd:COG1196    284 EEAQAEEYE-LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  338 IDKApdespyigksryKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGhtpLDTQLEDKEKKISAAQTRLSELH 417
Cdd:COG1196    363 AEEA------------LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE---LEEAEEALLERLERLEEELEELE 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  418 DEIEKAEQQILRATEEFKQLEEAI-QLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKE 496
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEaELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  497 Q--QLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEA--------LKKDLEGVISGLQeyLGTIKGQ 566
Cdd:COG1196    508 EgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaieyLKAAKAGRATFLP--LDKIRAR 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  567 ATQAQNECRKLRDEKETLLQRLTEVEQER-----DQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEA 641
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARyyvlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  642 ELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNalgKAQFSEEKEQENSELHAKLKHLQDDNNLLK 721
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA---EEERLEEELEEEALEEQLEAEREELLEELL 742

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 2462622367  722 QQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLK 756
Cdd:COG1196    743 EEEELLEEEALEELPEPPDLEELERELERLEREIE 777
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
83-250 2.79e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.12  E-value: 2.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   83 ITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNkiski 162
Cdd:COG4886     32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN----- 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  163 EGIENMCNLQKLNLAGNEIEHIPVWLGkKLKSLRVLNLKGNKISSLQdiSKLKPLQDLISLILVENPVVTLPHylqfTIF 242
Cdd:COG4886    107 EELSNLTNLESLDLSGNQLTDLPEELA-NLTNLKELDLSNNQLTDLP--EPLGNLTNLKSLDLSNNQLTDLPE----ELG 179


                   ....*...
gi 2462622367  243 HLRSLESL 250
Cdd:COG4886    180 NLTNLKEL 187
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1252-1779 3.08e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 3.08e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1252 EHHNLENEVSRLEDIMQHLKSKKREERwmrASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFidg 1331
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELE---AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR--- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1332 nveslmTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 1411
Cdd:COG1196    307 ------LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1412 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEM 1491
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1492 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV----------QAKADLQE 1561
Cdd:COG1196    461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligvEAAYEAAL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1562 ALRLGETEVTEKCNHIREVKSLLEELSFQKGE------LNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKN 1635
Cdd:COG1196    541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1636 ILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQS 1715
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1716 CVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLEL-----------NVRKLQQELDQLNRD 1779
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEeealeelpeppDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 421-734 6.87e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.24  E-value: 6.87e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  421 EKAEQQILRATEEFKQLEEAI-QLKKEALDLELQMEKQKQEIAgKQKEIKDLQIAI--DSLDSKDPKHSHMKAQKSGKEQ 497
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILnELERQLKSLERQAEKAERYKE-LKAELRELELALlvLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  498 QLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIaaneaLKKDLEGVISGLQEYLGTIKGQATQAQNECRKL 577
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN-----EISRLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  578 RDEKETLLQRLTEVEQERDQLEIvamDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQL 657
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKE---ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  658 KEELE----KVTRLTQLEQSALQAELEKERQALKNALG-KAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLN 732
Cdd:TIGR02168  406 EARLErledRRERLQQEIEELLKKLEEAELKELQAELEeLEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485


                   ..
gi 2462622367  733 HV 734
Cdd:TIGR02168  486 QL 487
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1304-1946 3.39e-11

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 68.92  E-value: 3.39e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1304 EKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEK--------SLKHHEDIVDEIECIEKTLLKRRSELREADR 1375
Cdd:TIGR00606  406 EAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKeilekkqeELKFVIKELQQLEGSSDRILELDQELRKAER 485

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1376 LLAEAE--SELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 1453
Cdd:TIGR00606  486 ELSKAEknSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSL 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1454 LKEINKIVAAKDSdFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLL-------------QAKRAELEKL 1520
Cdd:TIGR00606  566 LGYFPNKKQLEDW-LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLssyedklfdvcgsQDEESDLERL 644

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1521 KSQVTSQQQEMAVLD----------RQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 1590
Cdd:TIGR00606  645 KEEIEKSSKQRAMLAgatavysqfiTQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1591 KGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK-LQHDQRVSElektQVAVL 1669
Cdd:TIGR00606  725 RDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvCLTDVTIME----RFQME 800

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1670 EEKLELENLQQISQQQKGEIEWQKQLLERDKREIERmtaESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAE 1749
Cdd:TIGR00606  801 LKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQH---ELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIG 877

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1750 ENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH- 1828
Cdd:TIGR00606  878 TNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYm 957

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1829 -------QDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK---------LKLVQQEMMFQRLQKER 1892
Cdd:TIGR00606  958 kdienkiQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKiqerwlqdnLTLRKRENELKEVEEEL 1037

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1893 ESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQEEER 1946
Cdd:TIGR00606 1038 KQHLKEMGQMQVLQMKQEHQkLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 379-1073 4.31e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 68.71  E-value: 4.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  379 DEQLRNDHMNLRGHTpldTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQ--MEK 456
Cdd:pfam12128  229 DIQAIAGIMKIRPEF---TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKekRDE 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  457 QKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQldimnkQYQQLESRLDEILSRIAKETEEIKDLEEQLTE 536
Cdd:pfam12128  306 LNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE------QLPSWQSELENLEERLKALTGKHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  537 GQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKL---------------RDEKETLLQRLTEVEQERDQLEIV 601
Cdd:pfam12128  380 RRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALeselreqleagklefNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  602 AMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEA---ELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAE 678
Cdd:pfam12128  460 PELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKrrdQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  679 LEKERQALKNALGKAQFSEekeqensELHAKLKHLQDDNNLLKQQLKDFQNHLNhvVDGLVRPEEVAARvDELRRKLklg 758
Cdd:pfam12128  540 LRKEAPDWEQSIGKVISPE-------LLHRTDLDPEVWDGSVGGELNLYGVKLD--LKRIDVPEWAASE-EELRERL--- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  759 tgemnihspsDVLGKSL---ADLQKQFSEILARSKWERDEAQVRE---RKLQEEMALQQEKLATGQEEFRQACERALEAR 832
Cdd:pfam12128  607 ----------DKAEEALqsaREKQAAAEEQLVQANGELEKASREEtfaRTALKNARLDLRRLFDEKQSEKDKKNKALAER 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  833 mnfdKRQHEARIQQMENEIHYLQENLKSMEEIQgltDLQLQEADEEKeriLAQLRELEKKKKLEDAKSQEQVFGLDKELK 912
Cdd:pfam12128  677 ----KDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREARTEK---QAYWQVVEGALDAQLALLKAAIAARRSGAK 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  913 KLKKAVATS-----DKLATAELTIAK--DQLKSLHGTVMKINQERAEELQ----EAERFSRKAAQAARDLTRAEAEIELL 981
Cdd:pfam12128  747 AELKALETWykrdlASLGVDPDVIAKlkREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  982 QNLLRQKGEQFRLEMEKTGVGTGANSQVLeiEKLNETMERQRTEIARLQNV-LDLTGSDNKGGFENVLEEIAELRREVSY 1060
Cdd:pfam12128  827 QQQLARLIADTKLRRAKLEMERKASEKQQ--VRLSENLRGLRCEMSKLATLkEDANSEQAQGSIGERLAQLEDLKLKRDY 904

                          730
                   ....*....|...
gi 2462622367 1061 QNDYISSMADPFK 1073
Cdd:pfam12128  905 LSESVKKYVEHFK 917
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
96-280 5.57e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 67.27  E-value: 5.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   96 NLALIKSLNLSlskdgGKKFKYI-ENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKL 174
Cdd:COG4886    203 NLTNLEELDLS-----GNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  175 NLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQP 254
Cdd:COG4886    278 DLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLN 357

                          170       180
                   ....*....|....*....|....*.
gi 2462622367  255 VTTQDRQEAFERFSLEEVERLERDLE 280
Cdd:COG4886    358 LLSLLLTLLLTLGLLGLLEATLLTLA 383
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1256-2095 6.06e-11

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 68.15  E-value: 6.06e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHH---NIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGN 1332
Cdd:TIGR00606  212 LKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNrlkEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELK 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1333 VESLM--TELEIEKSLKHHEDIVDEIE----CIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFT--DAKRS 1404
Cdd:TIGR00606  292 MEKVFqgTDEQLNDLYHNHQRTVREKErelvDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRarDSLIQ 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1405 LLQTESDAEELER-----RAQETAVNLVKADQQlRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLT 1479
Cdd:TIGR00606  372 SLATRLELDGFERgpfseRQIKNFHTLVIERQE-DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1480 EELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRaELEKLKSQVTSQQQEMAVLdrqlghkkeelhllqgSMVQAKADL 1559
Cdd:TIGR00606  451 KKQEELKFVIKELQQLEGSSDRILELDQELRKAER-ELSKAEKNSLTETLKKEVK----------------SLQNEKADL 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1560 QEALRlGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDM 1639
Cdd:TIGR00606  514 DRKLR-KLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDR 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1640 LQLENHELQGLKLQHDQRVSELEKTQvAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVEC 1719
Cdd:TIGR00606  593 LAKLNKELASLEQNKNHINNELESKE-EQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQ 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1720 LSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKRE 1799
Cdd:TIGR00606  672 LTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1800 AVNSLQEELANVQDHLnlakqdllhttkhqdvllSEQTRLQKDISEWANRFEDCQKEEETKQQqlqvLQNEIEENKLKLV 1879
Cdd:TIGR00606  752 KLQKVNRDIQRLKNDI------------------EEQETLLGTIMPEEESAKVCLTDVTIMER----FQMELKDVERKIA 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1880 QQEmmfqrlqkereseeSKLETSKVTLKEQQhqLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTK 1959
Cdd:TIGR00606  810 QQA--------------AKLQGSDLDRTVQQ--VNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEK 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1960 RQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEAlkIQRSQLEKNLLMANQKDLERRQM 2039
Cdd:TIGR00606  874 LQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL--ISSKETSNKKAQDKVNDIKEKVK 951

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 2040 EISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENL 2095
Cdd:TIGR00606  952 NIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI 1007
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
395-1020 8.20e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 67.76  E-value: 8.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKK-----ISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQlkkealdlelqmekqkqEIAGKQKEIK 469
Cdd:PRK02224   192 LKAQIEEKEEKdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVLE-----------------EHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  470 DLQIAIDSLDSKdpkhshmkaqKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIkdleeQLTEGQIAANEALKKDL 549
Cdd:PRK02224   255 TLEAEIEDLRET----------IAETEREREELAEEVRDLRERLEELEEERDDLLAEA-----GLDDADAEAVEARREEL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  550 EGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivaMDAENMRKELAELESALQEQHEVNASL 629
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE---SELEEAREAVEDRREEIEELEEEIEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  630 QQTQGDLSAYEAELEARLNLRDAEANQLKEELekvtrltqleqsalqAELEKERQALKNALGKAQ--------------- 694
Cdd:PRK02224   397 RERFGDAPVDLGNAEDFLEELREERDELRERE---------------AELEATLRTARERVEEAEalleagkcpecgqpv 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  695 -------FSEEKEQENSELHAKLkhlqddnnllkQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSP 767
Cdd:PRK02224   462 egsphveTIEEDRERVEELEAEL-----------EDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRE 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  768 S-DVLGKSLADLQKQFSEILARSKWERDEAQvrerKLQEEMALQQEKLATGQEEfRQACERALEARMNFDKRQheARIQQ 846
Cdd:PRK02224   531 TiEEKRERAEELRERAAELEAEAEEKREAAA----EAEEEAEEAREEVAELNSK-LAELKERIESLERIRTLL--AAIAD 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  847 MENEIHYLQENLKSMEEIQgltdlqlqeaDEEKERiLAQLRelEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKlAT 926
Cdd:PRK02224   604 AEDEIERLREKREALAELN----------DERRER-LAEKR--ERKRELEAEFDEARIEEAREDKERAEEYLEQVEE-KL 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  927 AELTIAKDQLKSLHGTVmKINQERAEELQEaerfsRKAAQAAR--DLTRAEAEIELLQNLLRqkgeQFRLEMEKTGVGTg 1004
Cdd:PRK02224   670 DELREERDDLQAEIGAV-ENELEELEELRE-----RREALENRveALEALYDEAEELESMYG----DLRAELRQRNVET- 738

                          650
                   ....*....|....*.
gi 2462622367 1005 ansqvLEIeKLNETME 1020
Cdd:PRK02224   739 -----LER-MLNETFD 748
PTZ00121 PTZ00121
MAEBL; Provisional
 401-1011 1.46e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.09  E-value: 1.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  401 DKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQME-KQKQEIAGKQKEIKDLQIAIDSLD 479
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEeARKADELKKAEEKKKADEAKKAEE 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  480 SKDPKHSHMKAQKSGKEQQLdimNKQYQQLESRLDEILSRI--AKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQ 557
Cdd:PTZ00121  1301 KKKADEAKKKAEEAKKADEA---KKKAEEAKKKADAAKKKAeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  558 EYLGTIKGQATQAQ--NECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKElAELESALQEQHEVNASLQQTQGD 635
Cdd:PTZ00121  1378 KKADAAKKKAEEKKkaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA-DEAKKKAEEAKKADEAKKKAEEA 1456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  636 LSAYEAELEARLNLRDAEANQLKEELEKVTRLTQ-LEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQ 714
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKkAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA 1536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  715 DDNNLLKQQLKdfqnhlnhvVDGLVRPEEVaaRVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERD 794
Cdd:PTZ00121  1537 DEAKKAEEKKK---------ADELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  795 EAQVRERKLQEEMALQQEKLATGQEEfRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQE 874
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAEEE-KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  875 ADEEKerilaqlRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSlhgtvmkiNQERAEEL 954
Cdd:PTZ00121  1685 EDEKK-------AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE--------DKKKAEEA 1749

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462622367  955 QEAERFSRKAAQAARDLTRAEAEIE-----LLQNLLRQKGEQFRLEMEKTGVGTGANSQVLE 1011
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRkekeaVIEEELDEEDEKRRMEVDKKIKDIFDNFANII 1811
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1553-2095 1.87e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.63  E-value: 1.87e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1553 VQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELnvqiSERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTE 1632
Cdd:PRK03918   185 IKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKL----EKEVKELEELKEEIEELEKELESLEGSKRKLEEK 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1633 LKNILDMLQLENHELQGLKlqhdQRVSELEKTQVAVLEEKLELENLQQIsQQQKGEIEWQKQLLERDKREIERMTAESRA 1712
Cdd:PRK03918   261 IRELEERIEELKKEIEELE----EKVKELKELKEKAEEYIKLSEFYEEY-LDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1713 LQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEEnskMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDIS---A 1789
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE---LERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISkitA 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1790 MQQQLQEKREAVNSLQEELANVQDHLNLAKQDLlhTTKHQDVLLSEQTRLQKDISewanrfedcqKEEETKQQQLQVLQN 1869
Cdd:PRK03918   413 RIGELKKEIKELKKAIEELKKAKGKCPVCGREL--TEEHRKELLEEYTAELKRIE----------KELKEIEEKERKLRK 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1870 EIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQhQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCE 1949
Cdd:PRK03918   481 ELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELE-KKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1950 SLEKTLSQTKRQLSEREQQLVEKSGELLalqKEADSMRADFSLLRNQFLtERKKAEKQVASLKEALKIQRSQLEKNLLMA 2029
Cdd:PRK03918   560 ELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYL-ELKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367 2030 NQ--KDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENL 2095
Cdd:PRK03918   636 AEteKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 279-735 8.49e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.27  E-value: 8.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  279 LEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNElyaEIDKAPDESPYIGKSRYKRNMF 358
Cdd:TIGR04523  199 LELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT---QLNQLKDEQNKIKKQLSEKQKE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  359 ATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLE 438
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  439 -EAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKdpkHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEIL 517
Cdd:TIGR04523  356 sENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK---IQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  518 SRIAKETEEIKDLEEqltegQIAANEALKKDLEGVISGLQEYLGTIKGqatqaqnECRKLRDEKETLLQRLTEVEQERDQ 597
Cdd:TIGR04523  433 ETIIKNNSEIKDLTN-----QDSVKELIIKNLDNTRESLETQLKVLSR-------SINKIKQNLEQKQKELKSKEKELKK 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  598 LEIVAMDAENMRKEL-AELESALQEQHEVNASLQQTQGDLSAYEAE------------LEARLNLRDAEANQLKEELEKV 664
Cdd:TIGR04523  501 LNEEKKELEEKVKDLtKKISSLKEKIEKLESEKKEKESKISDLEDElnkddfelkkenLEKEIDEKNKEIEELKQTQKSL 580

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367  665 TRlTQLEQSALQAELEKERQALKNALgkaqfsEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVV 735
Cdd:TIGR04523  581 KK-KQEEKQELIDQKEKEKKDLIKEI------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 261-1034 8.67e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.37  E-value: 8.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  261 QEAFERFsLEEVERLERDLEKKMIETEELKSKQTRFLEE--IKNQDKLNK-SLKEEAML-----QKQSCEELKSDL-NTK 331
Cdd:pfam15921   73 KEHIERV-LEEYSHQVKDLQRRLNESNELHEKQKFYLRQsvIDLQTKLQEmQMERDAMAdirrrESQSQEDLRNQLqNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  332 NELYA----EIDKAPDESPYIGKSRykRNMFATE-------SYIIDSAQAVQiKKMEPDEQLRNDHMNLRGhtpldtqle 400
Cdd:pfam15921  152 HELEAakclKEDMLEDSNTQIEQLR--KMMLSHEgvlqeirSILVDFEEASG-KKIYEHDSMSTMHFRSLG--------- 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  401 dkekkiSAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALdLELQMEKQKQEIAGKQKEIKDLQiaidslds 480
Cdd:pfam15921  220 ------SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL-LQQHQDRIEQLISEHEVEITGLT-------- 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  481 kdPKHSHMKAQKSGKEQQLDIMNKQ-------YQQLESRLDEILSRIAKETEEIKDLEEQLTegqiaanEALKKDLEGVI 553
Cdd:pfam15921  285 --EKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYEDKI-------EELEKQLVLAN 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  554 SGLQEylgtIKGQATQAQNECRKLRDEKETLLQRLTEVEQE-------------RDQLEIVAMDaeNMRKELaelesalq 620
Cdd:pfam15921  356 SELTE----ARTERDQFSQESGNLDDQLQKLLADLHKREKElslekeqnkrlwdRDTGNSITID--HLRREL-------- 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  621 eqHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT-QLEQSA-LQAELEKERQALKNALGKAQFS-- 696
Cdd:pfam15921  422 --DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTaQLESTKeMLRKVVEELTAKKMTLESSERTvs 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  697 ------EEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVvdglvrpEEVAARVDELRRKLklgtgemnihSPSDV 770
Cdd:pfam15921  500 dltaslQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL-------RNVQTECEALKLQM----------AEKDK 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  771 LGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLatgqEEFrqaceRALEARMNFDKRQHEARIQQMENE 850
Cdd:pfam15921  563 VIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLEL----QEF-----KILKDKKDAKIRELEARVSDLELE 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  851 ----IHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQvfgldkelKKLKKAVATSDKLAT 926
Cdd:pfam15921  634 kvklVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM--------ETTTNKLKMQLKSAQ 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  927 AELTIAKDQLKSLHGT-------VMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLqnllrqKGEQFRLEMEKT 999
Cdd:pfam15921  706 SELEQTRNTLKSMEGSdghamkvAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFL------KEEKNKLSQELS 779

                          810       820       830
                   ....*....|....*....|....*....|....*
gi 2462622367 1000 GVGTGANSQVLEIEKLNETMERQRTEIARLQNVLD 1034
Cdd:pfam15921  780 TVATEKNKMAGELEVLRSQERRLKEKVANMEVALD 814
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1259-2066 9.40e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.22  E-value: 9.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1259 EVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEV------------EELHRTVQKRQQQK 1326
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyllyldylklneERIDLLQELLRDEQ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1327 DFIDGNVESLMTELEI-EKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSL 1405
Cdd:pfam02463  251 EEIESSKQEIEKEEEKlAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1406 LQTESDAEELERRAQE----TAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEE 1481
Cdd:pfam02463  331 KKEKEEIEELEKELKEleikREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1482 LQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQE 1561
Cdd:pfam02463  411 LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1562 ALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRqmskHKTELKNILDMLQ 1641
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEV----SATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1642 LENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLS 1721
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1722 KEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAV 1801
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1802 NSLQEELANVQdhLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 1881
Cdd:pfam02463  727 VQEAQDKINEE--LKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1882 EMMFQR-----LQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLA----AEERVRTLQEEERWCESLE 1952
Cdd:pfam02463  805 ALEEELkeeaeLLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEeitkEELLQELLLKEEELEEQKL 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1953 KTLSQTKRQLSEREQQLVE----KSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLM 2028
Cdd:pfam02463  885 KDELESKEEKEKEEKKELEeesqKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 2462622367 2029 ANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQF 2066
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1735-1968 9.65e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 62.86  E-value: 9.65e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 LN--LAKQDLLHTTKHQDVLLSeqtrlQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEEnklklvqqemmFQRLQKER 1892
Cdd:COG4942    106 LAelLRALYRLGRQPPLALLLS-----PEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-----------LAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 1893 ESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEErwcESLEKTLSQTKRQLSEREQQ 1968
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEA---EELEALIARLEAEAAAAAER 242
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 258-890 9.79e-10

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 64.30  E-value: 9.79e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  258 QDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKsdlnTKNELYAE 337
Cdd:TIGR00606  432 RDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETL----KKEVKSLQ 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  338 IDKApDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDH-------MNLRGHTPLDTQLED----KEKKI 406
Cdd:TIGR00606  508 NEKA-DLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKsrhsdelTSLLGYFPNKKQLEDwlhsKSKEI 586

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  407 SAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHS 486
Cdd:TIGR00606  587 NQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYS 666

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  487 HMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDlEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQ 566
Cdd:TIGR00606  667 QFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPD-KLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKE 745

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  567 ATQAQNECRKLRDEKETLLQRLTEVEQ-------ERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAy 639
Cdd:TIGR00606  746 IPELRNKLQKVNRDIQRLKNDIEEQETllgtimpEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTV- 824

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  640 eAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQA------ELEKERQALKNALGKAQF----SEEKEQENSELHAK 709
Cdd:TIGR00606  825 -QQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHlksktnELKSEKLQIGTNLQRRQQfeeqLVELSTEVQSLIRE 903

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  710 LKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAA-RVDELRRKLKLGTGEMNihSPSDVLGKSLADLQKQFSEILAR 788
Cdd:TIGR00606  904 IKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQdKVNDIKEKVKNIHGYMK--DIENKIQDGKDDYLKQKETELNT 981

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  789 SKWERDEAQVRERKLQEEMALQQEKLATGQEE------------FRQACERALEARMNFDKRQHEARIQQMENEIHYLQE 856
Cdd:TIGR00606  982 VNAQLEECEKHQEKINEDMRLMRQDIDTQKIQerwlqdnltlrkRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEE 1061

                          650       660       670
                   ....*....|....*....|....*....|....
gi 2462622367  857 NLKSMEEIQGLTDLQLQEADEEKERILAQLRELE 890
Cdd:TIGR00606 1062 NIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQ 1095
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
401-693 1.37e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.78  E-value: 1.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  401 DKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEaiqlKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDS 480
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQE----RREALQRLAEYSWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  481 KDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGL--QE 558
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAlgDA 762

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  559 YLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDA--------------------------------E 606
Cdd:COG4913    763 VERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDAdleslpeylalldrleedglpeyeerfkellnE 842

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  607 NMRKELAELESALQEQ--------HEVNASLQQTQ-GDLSAYEAELEARlnlRDAEANQLKEELEKVTRLTQLEQSALQA 677
Cdd:COG4913    843 NSIEFVADLLSKLRRAireikeriDPLNDSLKRIPfGPGRYLRLEARPR---PDPEVREFRQELRAVTSGASLFDEELSE 919

                          330
                   ....*....|....*.
gi 2462622367  678 ELEKERQALKNALGKA 693
Cdd:COG4913    920 ARFAALKRLIERLRSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 398-714 1.54e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 1.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  398 QLEDKEKKISAAQTRLSELHDEIEKAE--QQILRATEEFKQLEeaiqLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAI 475
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAEryQALLKEKREYEGYE----LLKEKEALERQKEAIERQLASLEEELEKLTEEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  476 DSLDskdpKHSHMKAQKSgKEQQLDIMNK---QYQQLESRLDEILSRIAKETEEIKDLEEQL--TEGQIAANEALKKDLE 550
Cdd:TIGR02169  261 SELE----KRLEEIEQLL-EELNKKIKDLgeeEQLRVKEKIGELEAEIASLERSIAEKERELedAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  551 GVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQE----RDQLEIVAMDAENMRKELAELESALQEQHEVN 626
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEfaetRDELKDYREKLEKLKREINELKRELDRLQEEL 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  627 ASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRltQLEQsaLQAELEKERQALKNALGK-AQFSEEKEQENSE 705
Cdd:TIGR02169  416 QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW--KLEQ--LAADLSKYEQELYDLKEEyDRVEKELSKLQRE 491


                   ....*....
gi 2462622367  706 LHAKLKHLQ 714
Cdd:TIGR02169  492 LAEAEAQAR 500
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1363-1729 1.59e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 1.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1363 LLKRRSELREADRLLAEAESELsctkEKTKNAVEkftDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKD 1442
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKI----AELEKALA---ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1443 LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNedhhlqvLKESEVLLQAKRAELEKLKS 1522
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE-------LKALREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1523 QVTSQQQEMAVLDRQLGHKKEELHLLQgsmvQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERK 1602
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLE----EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1603 TQLTlikqeiekeeeNLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELeKTQVAVLEEKLELENLQQIS 1682
Cdd:TIGR02168  894 SELE-----------ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL-QERLSEEYSLTLEEAEALEN 961

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462622367 1683 QQQKGEIEWQKQlLERDKREIERM-------TAESRALQSCVECLSKEKEDLQE 1729
Cdd:TIGR02168  962 KIEDDEEEARRR-LKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQKEDLTE 1014
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1350-1930 1.78e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.12  E-value: 1.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1350 EDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA 1429
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKND 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1430 DQQLRSLQADAKDLEQHKIKQEEILKEIN-------KIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDH---- 1498
Cdd:TIGR04523  116 KEQKNKLEVELNKLEKQKKENKKNIDKFLteikkkeKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKiknk 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1499 ---------HLQVLKESEVLLQAKRAELEK----LKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEA--- 1562
Cdd:TIGR04523  196 llklelllsNLKKKIQKNKSLESQISELKKqnnqLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKqke 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1563 LRLGETEVTEKCNHIREVKSLLEELSFQK-----GELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKN-- 1635
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLKSEISDLNNQKeqdwnKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNse 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1636 -----ILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAES 1710
Cdd:TIGR04523  356 senseKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETI 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1711 RALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAM 1790
Cdd:TIGR04523  436 IKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDL 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1791 QQQLQEKREAVNSLQEELANVQDHLNLAKQDL--LHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQ 1868
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELnkDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1869 NEIEENKLKLVQQEMMFQRLQKERES---EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSK 1930
Cdd:TIGR04523  596 KEKKDLIKEIEEKEKKISSLEKELEKakkENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1251-1845 1.82e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 1.82e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1251 PEHHNLENEVSRLEDIMQHLKSKKR--EERWMRASKRQSEKEMEELHHN--IDDLLQEKKSLECEVEELH---RTVQKRQ 1323
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEelEEQLETLRSKVAQLELQIASLNneIERLEARLERLEDRRERLQqeiEELLKKL 430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1324 QQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTkEKTKNAVEKFTDAKR 1403
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVK 509

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1404 SLLQTESD--------AEELERRAQ-ETAVNLVKAD--QQLRSLQADAKDLEQHKIKQEEI---------------LKEI 1457
Cdd:TIGR02168  510 ALLKNQSGlsgilgvlSELISVDEGyEAAIEAALGGrlQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikgteIQGN 589

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1458 NKIVAAKDSDFQCLSKKKEKLTEELQK--------------LQKDIEMAERNEDHHLQVLKESEVL-------------- 1509
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktn 669

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1510 --LQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEEL 1587
Cdd:TIGR02168  670 ssILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1588 SFQKGELNVQISERKTQLTlikqeiekeeenlqvvlrQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1667
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEE------------------RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1668 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAEsralqscVECLSKEKEDLQEKCDIWEKKLAQTKRVLAA 1747
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED-------IESLAAEIEELEELIEELESELEALLNERAS 884

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1748 AEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELAN-VQDHLNLAKQDLLHTT 1826
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeYSLTLEEAEALENKIE 964

                          650
                   ....*....|....*....
gi 2462622367 1827 KHQDVLLSEQTRLQKDISE 1845
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 396-738 2.30e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 2.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  396 DTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAi 475
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLA- 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  476 dsldskdpkhshmkaqksGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDL--EEQLT-EGQIAANEALKKDLEGV 552
Cdd:TIGR02169  248 ------------------SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRvKEKIGELEAEIASLERS 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  553 ISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivaMDAENMRKELAELESALQeqhEVNASLQQT 632
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT---EEYAELKEELEDLRAELE---EVDKEFAET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  633 QGDLSAYEAELEarlnlrdaEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGK-AQFSEEKEQENSELHA--- 708
Cdd:TIGR02169  384 RDELKDYREKLE--------KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKiNELEEEKEDKALEIKKqew 455

                          330       340       350
                   ....*....|....*....|....*....|
gi 2462622367  709 KLKHLQDDNNLLKQQLKDFQNHLNHVVDGL 738
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEYDRVEKEL 485
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1708-2013 2.77e-09

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 62.61  E-value: 2.77e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1708 AESRALQScVECLSKEKEDLQEKCDIWEKKLAQT-KRVLAAAEENSKME--QSNLEKLELN-----------VRKLQQEL 1773
Cdd:PLN02939   150 ARLQALED-LEKILTEKEALQGKINILEMRLSETdARIKLAAQEKIHVEilEEQLEKLRNEllirgateglcVHSLSKEL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1774 DQLNRDKLSLHNDISAMQQQLQEKREAVNSLqeelanvqdhLNLAKQDLLHTTKHQDvLLSEQTRLQKDISEWANRFEDC 1853
Cdd:PLN02939   229 DVLKEENMLLKDDIQFLKAELIEVAETEERV----------FKLEKERSLLDASLRE-LESKFIVAQEDVSKLSPLQYDC 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1854 QKEE-ETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEE----SKLETSKVTLKEQQHQLEKELTDQKSKldQVL 1928
Cdd:PLN02939   298 WWEKvENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKeanvSKFSSYKVELLQQKLKLLEERLQASDH--EIH 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1929 SKVLAAEERVRTLQeeerwcESLEKTLSQTKRQlsereqqlveksgellALQKEADSMRADF----SLLRNQFLTERKKA 2004
Cdd:PLN02939   376 SYIQLYQESIKEFQ------DTLSKLKEESKKR----------------SLEHPADDMPSEFwsriLLLIDGWLLEKKIS 433


                   ....*....
gi 2462622367 2005 EKQVASLKE 2013
Cdd:PLN02939   434 NNDAKLLRE 442
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 434-692 2.78e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.32  E-value: 2.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  434 FKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLdskdpkhshmkaqksgkEQQLDIMNKQYQQLESRL 513
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL-----------------ERRIAALARRIRALEQEL 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  514 DEILSRIAKETEEIKDLEEQLtegqiaanEALKKDLEGVI-----SGLQEYLGTIKGQATQAQNEcRKLRDEKETLLQRL 588
Cdd:COG4942     79 AALEAELAELEKEIAELRAEL--------EAQKEELAELLralyrLGRQPPLALLLSPEDFLDAV-RRLQYLKYLAPARR 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  589 TEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRL- 667
Cdd:COG4942    150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALi 229

                          250       260
                   ....*....|....*....|....*
gi 2462622367  668 TQLEQSALQAELEKERQALKNALGK 692
Cdd:COG4942    230 ARLEAEAAAAAERTPAAGFAALKGK 254
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
395-894 2.93e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 2.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEA----IQLKKEALDLELQMEKQKQEIAGKQKEIKD 470
Cdd:PRK03918   191 IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeiEELEKELESLEGSKRKLEEKIRELEERIEE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  471 LQIAIDSLDSKDPKHSHMKaqksGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQiaANEALKKDLE 550
Cdd:PRK03918   271 LKKEIEELEEKVKELKELK----EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE--EKEERLEELK 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  551 GVISGLQEYLGTIKGQAtQAQNECRKLRDEKETLLQRLTEVEQERDQLEIvamdaENMRKELAELESALQEQHEVNASLQ 630
Cdd:PRK03918   345 KKLKELEKRLEELEERH-ELYEEAKAKKEELERLKKRLTGLTPEKLEKEL-----EELEKAKEEIEEEISKITARIGELK 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  631 QTQGDLSAYEAEL----------------EARLNLRDAEANQLKEELEKVTRLTQLEQSA------LQAELEKERQALKN 688
Cdd:PRK03918   419 KEIKELKKAIEELkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLrkelreLEKVLKKESELIKL 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  689 ALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEM-NIHSP 767
Cdd:PRK03918   499 KELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELaELLKE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  768 SDVLG-KSLADLQKQFSEI---------LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDK 837
Cdd:PRK03918   579 LEELGfESVEELEERLKELepfyneyleLKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  838 RQHEA---RIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKK 894
Cdd:PRK03918   659 EEYEElreEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 398-595 3.66e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.32  E-value: 3.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  398 QLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAI-QLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAID 476
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIaALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  477 SLdSKDPKHSHMKAQKSGKEQQLDIMNKQ------------YQQLESRLDEILSRIAKETEEIKDLEEQLT------EGQ 538
Cdd:COG4942    101 AQ-KEELAELLRALYRLGRQPPLALLLSPedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEaeraelEAL 179

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367  539 IAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQER 595
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 259-599 3.81e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.81e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  259 DRQEAFERFSLEEVERLERDLEKKmIETEELKSKqtrfLEEIKNQDKLNKSLKEEAMLqkqscEELKSDLNTKNELYAEI 338
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKA-ERYQALLKE----KREYEGYELLKEKEALERQK-----EAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  339 DKAPDEspyigksrykRNMFATESYIIDSAQAVQIKKMEPDEQLRndhmnlrghtpLDTQLEDKEKKISAAQTRLSELHD 418
Cdd:TIGR02169  257 TEEISE----------LEKRLEEIEQLLEELNKKIKDLGEEEQLR-----------VKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  419 EIEKAEQQILRATEEF-KQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSkdpKHSHMKAQKSGKEQ 497
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIdKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK---EFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  498 QLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT--EGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECR 575
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgiEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472

                          330       340
                   ....*....|....*....|....
gi 2462622367  576 KLRDEKETLLQRLTEVEQERDQLE 599
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAE 496
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1352-2140 9.16e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 9.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1352 IVDEIECIEKTLLKRRSELREADRLlAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEEL-ERRAQETAVNLVKAD 1430
Cdd:TIGR02169  158 IIDEIAGVAEFDRKKEKALEELEEV-EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKrEYEGYELLKEKEALE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1431 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEE--------LQKLQKDIEMAERNEDHHLQV 1502
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrvkekIGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1503 LKESE-------VLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCN 1575
Cdd:TIGR02169  317 LEDAEerlakleAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1576 HIREVKSLLEELSF---QKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKl 1652
Cdd:TIGR02169  397 LKREINELKRELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK- 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1653 qhdQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAEsralqscvecLSKEKEDLQEKCD 1732
Cdd:TIGR02169  476 ---EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQ----------LGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1733 IwekklAQTKRVLAAAEENSKMEQSNLEKLE---------LNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS 1803
Cdd:TIGR02169  543 V-----AAGNRLNNVVVEDDAVAKEAIELLKrrkagratfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1804 -------LQEELANVQDHLNLAKQ-----DLLHTT-------KHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQL 1864
Cdd:TIGR02169  618 yvfgdtlVVEDIEAARRLMGKYRMvtlegELFEKSgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1865 QVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKE---QQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 1941
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1942 QEEErwcESLEKTLSQTKRQLSEREQQLVEKsgellalqkeadsmradfsllrnqfltERKKAEKQVASLKEALkiQRSQ 2021
Cdd:TIGR02169  778 EEAL---NDLEARLSHSRIPEIQAELSKLEE---------------------------EVSRIEARLREIEQKL--NRLT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2022 LEKNLLMANQKDLERRQMEISDAMRTLKSEVkDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLpftmne 2101
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEI-ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL------ 898

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 2462622367 2102 GPFEEKLNfsqvhimdehwRGEALREKLRHREDRLKAQL 2140
Cdd:TIGR02169  899 RELERKIE-----------ELEAQIEKKRKRLSELKAKL 926
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 414-835 1.34e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.47  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  414 SELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALD------------LELQMEKQKQEIAGKQKEIKDLQIAIDSLDsk 481
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLErlrrerekaeryQALLKEKREYEGYELLKEKEALERQKEAIE-- 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  482 dpkhshmkAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDL--EEQLT-EGQIAANEALKKDLEGVISGLQE 558
Cdd:TIGR02169  244 --------RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRvKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  559 YLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEivaMDAENMRKELAELESALQEqheVNASLQQTQGDLSA 638
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT---EEYAELKEELEDLRAELEE---VDKEFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  639 YEAELEarlnlrdaeanQLKEELEKVTRltqlEQSALQAELEKerqalknalgkaqfseeKEQENSELHAKLKHLQDDNN 718
Cdd:TIGR02169  390 YREKLE-----------KLKREINELKR----ELDRLQEELQR-----------------LSEELADLNAAIAGIEAKIN 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  719 LLKQQLKDFQNHLNHVVDGLvrpEEVAARVDELRRKLKlgtgemNIHSPSDVLGKSLADLQKQFSEILARSKWERDEaqV 798
Cdd:TIGR02169  438 ELEEEKEDKALEIKKQEWKL---EQLAADLSKYEQELY------DLKEEYDRVEKELSKLQRELAEAEAQARASEER--V 506

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 2462622367  799 RERKLQEEMALQQEKLATGQ--------EEFRQACERALEARMNF 835
Cdd:TIGR02169  507 RGGRAVEEVLKASIQGVHGTvaqlgsvgERYATAIEVAAGNRLNN 551
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 395-646 1.40e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 59.46  E-value: 1.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAI-QLKKEALDLELQMEKQKQEIAgkqKEIKDLQI 473
Cdd:COG3883     21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIdKLQAEIAEAEAEIEERREELG---ERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  474 AIDS-------LDSKDPKhshmkaqksgkeqqlDIMNKQyqqleSRLDEILSRIAKETEEIKDLEEQLTEgQIAANEALK 546
Cdd:COG3883     98 SGGSvsyldvlLGSESFS---------------DFLDRL-----SALSKIADADADLLEELKADKAELEA-KKAELEAKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  547 KDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVN 626
Cdd:COG3883    157 AELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236

                          250       260
                   ....*....|....*....|
gi 2462622367  627 ASLQQTQGDLSAYEAELEAR 646
Cdd:COG3883    237 AAAAAAAASAAGAGAAGAAG 256
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 270-1075 1.45e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.37  E-value: 1.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  270 EEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELYAEIdkapdespYIG 349
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKL--------NEE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  350 KSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHmnlrghtpldtqleDKEKKISAAQTRLSELHDEIEKAEQQILR 429
Cdd:pfam02463  238 RIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKEN--------------KEEEKEKKLQEEELKLLAKEEEELKSELL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  430 ATEEFKQLEEAIQ--LKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQ 507
Cdd:pfam02463  304 KLERRKVDDEEKLkeSEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  508 QLESRLDEILS---RIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETL 584
Cdd:pfam02463  384 ERLSSAAKLKEeelELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  585 LQRLTEVEQERDQLEIVA----MDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEE 660
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKlqeqLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  661 LEKVTRLTQLEQSALQAELEKERQA----LKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVD 736
Cdd:pfam02463  544 AISTAVIVEVSATADEVEERQKLVRalteLPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  737 GLVRPEEVAARVDELRRKLKLGTGEMNIHSpSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLAT 816
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVS-LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIK 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  817 GQEEFRQACER--ALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQ-LRELEKKK 893
Cdd:pfam02463  703 KKEQREKEELKklKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEkELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  894 KLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTR 973
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  974 AEAEIELLQNLLRQKGEQFRLEMEKTGvgtGANSQVLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAE 1053
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELE---SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939

                          810       820
                   ....*....|....*....|..
gi 2462622367 1054 LRREVSYQNDYISSMADPFKRR 1075
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEER 961
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
395-637 1.98e-08

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 59.65  E-value: 1.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAA----QTRLSELHDEIEKAEQQIlratEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKD 470
Cdd:COG3206    162 LEQNLELRREEARKAleflEEQLPELRKELEEAEAAL----EEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  471 LQIAIDSLDSKDPKHSHMKAQKSGkEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLtegqiaanEALKKDLE 550
Cdd:COG3206    238 AEARLAALRAQLGSGPDALPELLQ-SPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQI--------AALRAQLQ 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  551 gviSGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELesaLQEQHEVNASLQ 630
Cdd:COG3206    309 ---QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESL---LQRLEEARLAEA 382


                   ....*..
gi 2462622367  631 QTQGDLS 637
Cdd:COG3206    383 LTVGNVR 389
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
246-726 2.62e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  246 SLESLEGQPVTTQDRQEAFE------RFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAmlqkq 319
Cdd:PRK02224   221 EIERYEEQREQARETRDEADevleehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER----- 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  320 scEELKSDlntknelyAEIDKAPDESpyigksrykrnmfatesyiidsaqavqikkmepdeqlrndhmnlrghtpLDTQL 399
Cdd:PRK02224   296 --DDLLAE--------AGLDDADAEA-------------------------------------------------VEARR 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  400 EDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEE-AIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSL 478
Cdd:PRK02224   317 EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEErAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  479 dskdpkhshmKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQiAANEALK-----KDLEGvi 553
Cdd:PRK02224   397 ----------RERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAE-ALLEAGKcpecgQPVEG-- 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  554 SGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQER---DQLEIVAMDAENMRKELAELESALQEQHEVNASLQ 630
Cdd:PRK02224   464 SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVeaeDRIERLEERREDLEELIAERRETIEEKRERAEELR 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  631 QTQGDLSAyEAElEARlnlrdAEANQLKEELEKV-TRLTQLEQSalQAELEKERQALKNALGKAQFSEEKEQENSELHAK 709
Cdd:PRK02224   544 ERAAELEA-EAE-EKR-----EAAAEAEEEAEEArEEVAELNSK--LAELKERIESLERIRTLLAAIADAEDEIERLREK 614

                          490
                   ....*....|....*..
gi 2462622367  710 LKHLQDDNNLLKQQLKD 726
Cdd:PRK02224   615 REALAELNDERRERLAE 631
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 474-705 5.90e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 57.53  E-value: 5.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  474 AIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQiAANEALKKDLEGVI 553
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE-AEIEERREELGERA 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  554 SGLQE------YLGTIKGQATQAqnecrklrdekeTLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQhevNA 627
Cdd:COG3883     93 RALYRsggsvsYLDVLLGSESFS------------DFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK---LA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  628 SLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSE 705
Cdd:COG3883    158 ELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1744-1985 8.98e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 56.76  E-value: 8.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1744 VLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLL 1823
Cdd:COG3883     10 TPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1824 HTTKHQ----------DVLLSeqtrlQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKlklvqqemmfqRLQKERE 1893
Cdd:COG3883     90 ERARALyrsggsvsylDVLLG-----SESFSDFLDRLSALSKIADADADLLEELKADKAELE-----------AKKAELE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1894 SEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKS 1973
Cdd:COG3883    154 AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233

                          250
                   ....*....|..
gi 2462622367 1974 GELLALQKEADS 1985
Cdd:COG3883    234 AAAAAAAAAAAS 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
496-704 1.30e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 56.95  E-value: 1.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  496 EQQLDIMNKQYQQLESRLDEILSR--IAKETEEIKDLEEQLTE--GQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQ 571
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSEleSQLAEARAELAEAEARLAALRAQLGSGPDALPELL 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  572 NEcrklrDEKETLLQRLTEVEQERDQLEIVAMDA----ENMRKELAELESALQEQhevnasLQQTQGDLSAYEAELEARL 647
Cdd:COG3206    261 QS-----PVIQQLRAQLAELEAELAELSARYTPNhpdvIALRAQIAALRAQLQQE------AQRILASLEAELEALQARE 329

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367  648 NLRDAEANQLKEELEKVTRLtQLEQSALQAELEKERQALKNALGKAQFSEEKEQENS 704
Cdd:COG3206    330 ASLQAQLAQLEARLAELPEL-EAELRRLEREVEVARELYESLLQRLEEARLAEALTV 385
PTZ00121 PTZ00121
MAEBL; Provisional
 383-1057 1.47e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 1.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  383 RNDHMN-LRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLE---------- 451
Cdd:PTZ00121  1062 AKAHVGqDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEearkaedark 1141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  452 -----LQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHmKAQKSGKEQQLDIMNKQYQQLESRLDEILSRI------ 520
Cdd:PTZ00121  1142 aeearKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAAR-KAEEVRKAEELRKAEDARKAEAARKAEEERKAeearka 1220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  521 --AKETEEIKDLEEQLTEGQIA-------ANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEV 591
Cdd:PTZ00121  1221 edAKKAEAVKKAEEAKKDAEEAkkaeeerNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE 1300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  592 EQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARlnlrdAEANQLKEELEKVTRLTQLE 671
Cdd:PTZ00121  1301 KKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA-----ADEAEAAEEKAEAAEKKKEE 1375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  672 QSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQnhlnhvVDGLVRPEEVAARVDEL 751
Cdd:PTZ00121  1376 AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKK------ADEAKKKAEEAKKADEA 1449

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  752 RRKLKLGTGEMNIHSPSDVLGKSlADLQKQFSEilaRSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACE--RAL 829
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKA-DEAKKKAEE---AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEakKAD 1525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  830 EARMNFDKRQHEARIQQMENEihyLQENLKSMEEIQGLTDL-QLQEADEEKERILAQLRELEKKKKLEDAKSQE--QVFG 906
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKK---KADELKKAEELKKAEEKkKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEvmKLYE 1602

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  907 LDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQE--RAEELQEAERFSR-KAAQAAR----DLTRAEaEIE 979
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEkkKAEELKKAEEENKiKAAEEAKkaeeDKKKAE-EAK 1681

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  980 LLQNLLRQKGEQFRLEMEKTgvgtganSQVLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAELRRE 1057
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEA-------KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1256-1910 1.49e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 1.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKRE--ERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTV-----QKRQQQKDF 1328
Cdd:pfam15921  236 LKGRIFPVEDQLEALKSESQNkiELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqeQARNQNSMY 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1329 ID--GNVESLMTEL--EIEKSLKHHEDivdEIECIEKTLLKRRSELREA------------------DRLLAE---AESE 1383
Cdd:pfam15921  316 MRqlSDLESTVSQLrsELREAKRMYED---KIEELEKQLVLANSELTEArterdqfsqesgnlddqlQKLLADlhkREKE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1384 LSCTKEKTKNAVEKFTDAKRSL--LQTESDAEELERRAQETAVNLVKAD------QQLRSLQAdakdleqhkikQEEILK 1455
Cdd:pfam15921  393 LSLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAMKSEcqgqmeRQMAAIQG-----------KNESLE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1456 EINKIVAAKDSDFQCLskkkEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLd 1535
Cdd:pfam15921  462 KVSSLTAQLESTKEML----RKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHL- 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1536 rqlghKKEELHLLQgsmVQAKAdlqEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTlikqeieke 1615
Cdd:pfam15921  537 -----KNEGDHLRN---VQTEC---EALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE--------- 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1616 eenlqvvlRQMSKHKTELKnildmlqlenhELQGLKLQHDQRVSELEKtqvavleeklelenlqQISQQQKGEIEWQKQL 1695
Cdd:pfam15921  597 --------KEINDRRLELQ-----------EFKILKDKKDAKIRELEA----------------RVSDLELEKVKLVNAG 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1696 LERdKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLaqtkrvlaaaEENSKMEQSNLEKLELNVRKLQQELDQ 1775
Cdd:pfam15921  642 SER-LRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNF----------RNKSEEMETTTNKLKMQLKSAQSELEQ 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1776 LNRDKLSLHND-------ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN 1848
Cdd:pfam15921  711 TRNTLKSMEGSdghamkvAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAG 790

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462622367 1849 RFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRlqKERESEESKLETSkVTLKEQQ 1910
Cdd:pfam15921  791 ELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQR--QEQESVRLKLQHT-LDVKELQ 849
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
566-995 1.58e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 1.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  566 QATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESA---LQEQHEVNASLQQTQGDLSAYEAE 642
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlplYQELEALEAELAELPERLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  643 LEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNAlgkaqfsEEKEQENSELHAKLKHLQDDNNLLKQ 722
Cdd:COG4717    155 LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL-------EELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  723 QLKDFQNHLnhvvdglvRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQK----------QFSEILARSKWE 792
Cdd:COG4717    228 ELEQLENEL--------EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllaLLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  793 RDEAQVRERKLQEEMALQQEKLATGQEEFRqaCERALEARMNFDKRQHEARIQQMENEIHYLQENLK---SMEEIQGLTD 869
Cdd:COG4717    300 LGKEAEELQALPALEELEEEELEELLAALG--LPPDLSPEELLELLDRIEELQELLREAEELEEELQleeLEQEIAALLA 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  870 LQLQEADEEKERILAQLREL-EKKKKLEDAKSQ-EQVFGLDKELKKLKKAVATSDKLATAELTIA--KDQLKSLHGTVMK 945
Cdd:COG4717    378 EAGVEDEEELRAALEQAEEYqELKEELEELEEQlEELLGELEELLEALDEEELEEELEELEEELEelEEELEELREELAE 457

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367  946 INQ-----ERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLE 995
Cdd:COG4717    458 LEAeleqlEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1255-1809 1.58e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 1.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1255 NLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKrqqqkdfidgnve 1334
Cdd:PRK03918   225 KLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK------------- 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1335 slmtELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESElsctKEKTKNAVEKFTDAKRSLLQTESDAEE 1414
Cdd:PRK03918   292 ----AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEK----EERLEELKKKLKELEKRLEELEERHEL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1415 LER-RAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKdSDFQCLSKKKEKLTEELQKLQKDIEMAE 1493
Cdd:PRK03918   364 YEEaKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARI-GELKKEIKELKKAIEELKKAKGKCPVCG 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1494 R--NEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQgsMVQAKADLQEALRLGETEVT 1571
Cdd:PRK03918   443 RelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE--LAEQLKELEEKLKKYNLEEL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1572 EKCNhiREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEkeeenLQVVLRQMSKHKTELKNILDMLQLENHElqglk 1651
Cdd:PRK03918   521 EKKA--EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAE-----LEKKLDELEEELAELLKELEELGFESVE----- 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1652 lQHDQRVSELEKTQVAVLEEKLElenlqqisqqqKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKC 1731
Cdd:PRK03918   589 -ELEERLKELEPFYNEYLELKDA-----------EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1732 DIWE-----KKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNdISAMQQQLQEKREAVNSLQE 1806
Cdd:PRK03918   657 SEEEyeelrEEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK-LEKALERVEELREKVKKYKA 735


                   ...
gi 2462622367 1807 ELA 1809
Cdd:PRK03918   736 LLK 738
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1692-1934 2.06e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1692 QKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQ 1771
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1772 ELDQLnRDKLSlhNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQdllhttkhqdvLLSEQTRLQKDISEWANRFE 1851
Cdd:COG4942     98 ELEAQ-KEELA--ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKY-----------LAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1852 DCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1931
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ...
gi 2462622367 1932 LAA 1934
Cdd:COG4942    244 PAA 246
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
465-1057 2.16e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 2.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  465 QKEIKDLQIAIDSLDSK----DPKHSHMKAQKSGKEQQLDimnkqyqqlesRLDEILSRIAKETEEIKDLEEQLTEGQ-- 538
Cdd:PRK02224   198 EKEEKDLHERLNGLESElaelDEEIERYEEQREQARETRD-----------EADEVLEEHEERREELETLEAEIEDLRet 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  539 IAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLeivamdaenmRKELAELESA 618
Cdd:PRK02224   267 IAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL----------RDRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  619 LQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKvtrlTQLEQSALQAELEKERQALKNA---LGKAQ- 694
Cdd:PRK02224   337 AQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED----RREEIEELEEEIEELRERFGDApvdLGNAEd 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  695 FSEEKEQENSELHAKLKHLQDDnnllkqqlkdfqnhlnhvvdgLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVlgKS 774
Cdd:PRK02224   413 FLEELREERDELREREAELEAT---------------------LRTARERVEEAEALLEAGKCPECGQPVEGSPHV--ET 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  775 LADLQKQFSEILA-RSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEarmnfdkrQHEARIQQMENEIHY 853
Cdd:PRK02224   470 IEEDRERVEELEAeLEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIA--------ERRETIEEKRERAEE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  854 LQENLKSMEEiqgltdlqlqEADEEKERilAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDklatAELTIAK 933
Cdd:PRK02224   542 LRERAAELEA----------EAEEKREA--AAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL----AAIADAE 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  934 DQLKSLhgtvmkinQERAEELQEAERFSRKAAQAARDLTRA------EAEIELLQNLlRQKGEQFrlemektgvgtgans 1007
Cdd:PRK02224   606 DEIERL--------REKREALAELNDERRERLAEKRERKREleaefdEARIEEARED-KERAEEY--------------- 661

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1008 qvleIEKLNETMERQRTEIARLQNVLdltgsdnkGGFENVLEEIAELRRE 1057
Cdd:PRK02224   662 ----LEQVEEKLDELREERDDLQAEI--------GAVENELEELEELRER 699
LRR_8 pfam13855
Leucine rich repeat;
148-205 2.34e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.45  E-value: 2.34e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367  148 KLRELNLSYNKISKIEG--IENMCNLQKLNLAGNEIEHI-PVWLGKkLKSLRVLNLKGNKI 205
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLsPGAFSG-LPSLRYLDLSGNRL 61
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
501-892 2.61e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  501 IMNKQYQQLESRLDEILSRIAKETEEIKDLEEqlTEGQIAANEALKKDLEGVISGLQEYLgtikgQATQAQNECRKLRDE 580
Cdd:COG4717     68 LNLKELKELEEELKEAEEKEEEYAELQEELEE--LEEELEELEAELEELREELEKLEKLL-----QLLPLYQELEALEAE 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  581 KETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHE-VNASLQQTQGDLSAYEAELEARLNLRDAEANQLKE 659
Cdd:COG4717    141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEqLSLATEEELQDLAEELEELQQRLAELEEELEEAQE 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  660 ELEKVT-RLTQLEQSALQAELEKERQALKNALG-----------------------------------------KAQFSE 697
Cdd:COG4717    221 ELEELEeELEQLENELEAAALEERLKEARLLLLiaaallallglggsllsliltiagvlflvlgllallflllaREKASL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  698 EKEQENSELHAKLKHLQDDNnlLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHspsdvlgkslaD 777
Cdd:COG4717    301 GKEAEELQALPALEELEEEE--LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE-----------E 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  778 LQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQEN 857
Cdd:COG4717    368 LEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEE 447

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 2462622367  858 LKSM-EEIQGL--------TDLQLQEADEEKERILAQLRELEKK 892
Cdd:COG4717    448 LEELrEELAELeaeleqleEDGELAELLQELEELKAELRELAEE 491
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 451-696 2.90e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 55.22  E-value: 2.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  451 ELQMEKQKQEIAGKQKEIKDLQIAIDSLDskdpkhshmkaqksgkeQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDL 530
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQ-----------------AELEELNEEYNELQAELEALQAEIDKLQAEIAEA 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  531 EEQLTEGQIAANEALK------------------KDLEGVISGLqEYLGTIkgqATQAQNECRKLRDEKETLLQRLTEVE 592
Cdd:COG3883     78 EAEIEERREELGERARalyrsggsvsyldvllgsESFSDFLDRL-SALSKI---ADADADLLEELKADKAELEAKKAELE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  593 QERDQLEIVAMDAENMRKelaELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQ 672
Cdd:COG3883    154 AKLAELEALKAELEAAKA---ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230

                          250       260
                   ....*....|....*....|....
gi 2462622367  673 SALQAELEKERQALKNALGKAQFS 696
Cdd:COG3883    231 AAAAAAAAAAAAAASAAGAGAAGA 254
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1292-2096 3.43e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1292 EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDgnveslmteleiekslkhheDIVDEIECIEKTLLKRRSELR 1371
Cdd:pfam02463  152 PERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELII--------------------DLEELKLQELKLKEQAKKALE 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1372 EADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQE 1451
Cdd:pfam02463  212 YYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLL 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1452 EILKEINKIVAAK-DSDFQCLSKKKEKLTEELQKLQKDIEMAernedhhlqvlKESEVLLQAKRAELEKLKSQVTSQQQE 1530
Cdd:pfam02463  292 AKEEEELKSELLKlERRKVDDEEKLKESEKEKKKAEKELKKE-----------KEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1531 MAVLDRQLGHKKEELHLLQGsmvQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ 1610
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKK---LESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEE 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1611 EIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIE 1690
Cdd:pfam02463  438 SIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIK 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1691 WQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQ 1770
Cdd:pfam02463  518 DGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVL 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1771 QELDQLNRDKLSLHndisAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRF 1850
Cdd:pfam02463  598 EIDPILNLAQLDKA----TLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTK 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1851 EDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKldqVLSK 1930
Cdd:pfam02463  674 ELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID---EEEE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1931 VLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVAS 2010
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKI 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2011 LKEALKiqrsQLEKNLLMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELES 2090
Cdd:pfam02463  831 KEEELE----ELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEES 906


                   ....*.
gi 2462622367 2091 LKENLP 2096
Cdd:pfam02463  907 QKLNLL 912
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1471-2093 4.45e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.36  E-value: 4.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1471 LSKKKEKLTEELQKLQKDIEMAERNEDHHLQVL----KESEVLLQAKRAELEKLKSQVTSQQQEMAvLDRQLGHKKEELH 1546
Cdd:TIGR00618  192 LHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLekelKHLREALQQTQQSHAYLTQKREAQEEQLK-KQQLLKQLRARIE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1547 LLQgSMVQAKADLQEALrlgetEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQM 1626
Cdd:TIGR00618  271 ELR-AQEAVLEETQERI-----NRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQR 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1627 SKHKT-------------ELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQK 1693
Cdd:TIGR00618  345 RLLQTlhsqeihirdaheVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQG 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1694 QLLERDKREI---ERMTAESRALQSCVECLSKEKEDLQE---KCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVR 1767
Cdd:TIGR00618  425 QLAHAKKQQElqqRYAELCAAAITCTAQCEKLEKIHLQEsaqSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPC 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1768 KLQQELDQLNRdKLSLHNDISAMQQQLQEKREAVNSLQEELANVQdhlnlakQDLLHTTKHQDVLLSEQTRLQKDISEWA 1847
Cdd:TIGR00618  505 PLCGSCIHPNP-ARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVY-------HQLTSERKQRASLKEQMQEIQQSFSILT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1848 NRFEDCQKEEETKQQQLQVLQNEIEENklklvqqemmfqrlQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQV 1927
Cdd:TIGR00618  577 QCDNRSKEDIPNLQNITVRLQDLTEKL--------------SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1928 LSKVLAAEERVRTLQEEERwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQfLTERKKAEKQ 2007
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVR--EHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREL-ETHIEEYDRE 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2008 VASLKEALKIQRSQLEKNLLMANQ--KDLERRQMEISDAmRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLE 2085
Cdd:TIGR00618  720 FNEIENASSSLGSDLAAREDALNQslKELMHQARTVLKA-RTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDT 798


                   ....*...
gi 2462622367 2086 GELESLKE 2093
Cdd:TIGR00618  799 HLLKTLEA 806
LRR_8 pfam13855
Leucine rich repeat;
126-181 4.75e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 4.75e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  126 KLEVLNLSYNLIGKIEK--LDKLLKLRELNLSYNKISKIEG--IENMCNLQKLNLAGNEI 181
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
398-828 5.33e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 5.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  398 QLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQL-----KKEALDLEL--------QMEKQKQEIAGK 464
Cdd:COG4717     82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlplyqELEALEAELaelperleELEERLEELREL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  465 QKEIKDLQIAIDSLDSKdpKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQiaaNEA 544
Cdd:COG4717    162 EEELEELEAELAELQEE--LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE---NEL 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  545 LKKDLEGVISGLQEYLGTIKGQATQAQnecrkLRDEKETLLQRLTEVEQERdqLEIVAMDAENMRKELAELESALQEQHE 624
Cdd:COG4717    237 EAAALEERLKEARLLLLIAAALLALLG-----LGGSLLSLILTIAGVLFLV--LGLLALLFLLLAREKASLGKEAEELQA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  625 VNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKV-TRLTQLEQSALQAELEKERQALKNALGKAQFSEEKE-QE 702
Cdd:COG4717    310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELqELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElRA 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  703 NSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVrPEEVAARVDELRRKLKLGTGEMnihspsDVLGKSLADLQKQF 782
Cdd:COG4717    390 ALEQAEEYQELKEELEELEEQLEELLGELEELLEALD-EEELEEELEELEEELEELEEEL------EELREELAELEAEL 462

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 2462622367  783 SEILARSKWERDEAQVRERKLQ-EEMALQQEKLATGQEEFRQACERA 828
Cdd:COG4717    463 EQLEEDGELAELLQELEELKAElRELAEEWAALKLALELLEEAREEY 509
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 270-738 5.39e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 5.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  270 EEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELYAEIDKApdespyIG 349
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKN------ID 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  350 KSRYKRNMFATESYIIDSaqavQIKKmepdeqlrndhmnlrgHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILR 429
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKK----KIQK----------------NKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  430 ATEEFKQL-EEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKdpkhshmKAQKSGKE--QQLDIMNKQY 506
Cdd:TIGR04523  251 TQTQLNQLkDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ-------KEQDWNKElkSELKNQEKKL 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  507 QQLESRLDEILSRIAKETEEIKDLEEQLTEGQiAANEALKKDLEGVISGLQeylgTIKGQATQAQNECRKLRDEKETLLQ 586
Cdd:TIGR04523  324 EEIQNQISQNNKIISQLNEQISQLKKELTNSE-SENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  587 RLTEVEQERDQLEIvamDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTR 666
Cdd:TIGR04523  399 KIQNQEKLNQQKDE---QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462622367  667 L---TQLEQSALQAELEKERQALKNALGKAQFSEEK----EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGL 738
Cdd:TIGR04523  476 SinkIKQNLEQKQKELKSKEKELKKLNEEKKELEEKvkdlTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL 554
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
496-869 5.47e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 5.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  496 EQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTE-GQIAANEALKKDLEGVISGLQEyLGTIKGQATQAQNEC 574
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlQRLAEYSWDEIDVASAEREIAE-LEAELERLDASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  575 RKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTqgdlsAYEAELEARL--NLRDA 652
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL-----ELRALLEERFaaALGDA 762

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  653 EANQLKEELEKvtrltqlEQSALQAELEKERQALKNALgkAQFSEEKEQENSELHAKLkhlqDDNNllkqqlkDFQNHLN 732
Cdd:COG4913    763 VERELRENLEE-------RIDALRARLNRAEEELERAM--RAFNREWPAETADLDADL----ESLP-------EYLALLD 822

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  733 HVV-DGLVRPEEvaarvdELRRKLKlgtgEMNIHSPSDVLGK---SLADLQKQFSEI---LARSKWERDEA---QVRERK 802
Cdd:COG4913    823 RLEeDGLPEYEE------RFKELLN----ENSIEFVADLLSKlrrAIREIKERIDPLndsLKRIPFGPGRYlrlEARPRP 892

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462622367  803 LQEEmalqqeklatgqEEFRQACERALEARMNFDKRQHEARIQQMENEIHYL--QENLKSMEEIQGLTD 869
Cdd:COG4913    893 DPEV------------REFRQELRAVTSGASLFDEELSEARFAALKRLIERLrsEEEESDRRWRARVLD 949
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 588-901 6.66e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 6.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  588 LTEVEQERDQLEIVAMDAENMRKELAELESA-----LQEQHEVNASLQQTQGDLSAYEAELEAR------LNLRDAEANQ 656
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYegyelLKEKEALERQKEAIERQLASLEEELEKLteeiseLEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  657 LKEEL-EKVTRLTQLEQSALQAELEKERQALKNALGKAqfsEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLnhvv 735
Cdd:TIGR02169  273 LLEELnKKIKDLGEEEQLRVKEKIGELEAEIASLERSI---AEKERELEDAEERLAKLEAEIDKLLAEIEELEREI---- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  736 dglvrpEEVAARVDELRRKLKlgtgemnihSPSDVLGKSLADLQkQFSEILARSKWERDEAQVRERKLQEEMALQQEKLA 815
Cdd:TIGR02169  346 ------EEERKRRDKLTEEYA---------ELKEELEDLRAELE-EVDKEFAETRDELKDYREKLEKLKREINELKRELD 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  816 TGQEEFRQACERALEARMnfDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEkkKKL 895
Cdd:TIGR02169  410 RLQEELQRLSEELADLNA--AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE--KEL 485


                   ....*.
gi 2462622367  896 EDAKSQ 901
Cdd:TIGR02169  486 SKLQRE 491
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1252-1665 7.44e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.73  E-value: 7.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1252 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDD---LLQEKKSLECEVEELHRTVQK-----RQ 1323
Cdd:pfam05483  368 EQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEdekLLDEKKQFEKIAEELKGKEQElifllQA 447

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1324 QQKDFIDGNVESLMTELEIEKSLKHHEDIVDEiecIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKR 1403
Cdd:pfam05483  448 REKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE---LEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIIN 524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1404 SLLQTESDAEELErRAQETAVNLVKADQQLRSLQADAKDLEQHKI-KQEEILKEINKIVAAKDSDFQCLSKKKEKLTEEL 1482
Cdd:pfam05483  525 CKKQEERMLKQIE-NLEEKEMNLRDELESVREEFIQKGDEVKCKLdKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1483 QKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVL----DRQLGHKKEELHLLQGSMVQAKAD 1558
Cdd:pfam05483  604 ENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAI 683

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1559 LQEALRLgETEVTEKCNH-IREVKSLLEELSFQKGELnvqISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNIL 1637
Cdd:pfam05483  684 ADEAVKL-QKEIDKRCQHkIAEMVALMEKHKHQYDKI---IEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLK 759

                          410       420
                   ....*....|....*....|....*...
gi 2462622367 1638 DMLQLENHELQGLKLQHDQRVSELEKTQ 1665
Cdd:pfam05483  760 KQLEIEKEEKEKLKMEAKENTAILKDKK 787
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1256-1953 8.29e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 8.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKrqqqkdfidgnves 1335
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEK-------------- 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1336 lmteleIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELsctkEKTKNAVEKFTDAKRSLLQTESDAEEL 1415
Cdd:PRK03918   226 ------LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERI----EELKKEIEELEEKVKELKELKEKAEEY 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1416 ERRAQEtavnLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKivaaKDSDFQCLSKKKEKLTEELQKLQKDIEMAERn 1495
Cdd:PRK03918   296 IKLSEF----YEEYLDELREIEKRLSRLEEEINGIEERIKELEE----KEERLEELKKKLKELEKRLEELEERHELYEE- 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1496 edhhlqvlkesevlLQAKRAELEKLKSQVTsqqqemavldrqlGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCN 1575
Cdd:PRK03918   367 --------------AKAKKEELERLKKRLT-------------GLTPEKLEKELEELEKAKEEIEEEISKITARIGELKK 419

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1576 HIREVKSLLEELSFQKGELNVQISErktqltlikqEIEKEEENLqvvlrqMSKHKTELKNILDMLQLENHELQGLKlqhd 1655
Cdd:PRK03918   420 EIKELKKAIEELKKAKGKCPVCGRE----------LTEEHRKEL------LEEYTAELKRIEKELKEIEEKERKLR---- 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1656 QRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKcdiwe 1735
Cdd:PRK03918   480 KELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEEL----- 554

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1736 kklaqtkrvlaaaeenskmeQSNLEKLELNVRKLQQELDQLNRDKLSL-HNDISAMQQQLQEKREAVNSLQEelanvqdh 1814
Cdd:PRK03918   555 --------------------KKKLAELEKKLDELEEELAELLKELEELgFESVEELEERLKELEPFYNEYLE-------- 606

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 LNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQvlQNEIEENKLKLVQQEMMFQRLQKERES 1894
Cdd:PRK03918   607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEE 684

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 1895 EESKLETSKVTLKEQQHQLE--KELTDQKSKLDQVLSKVLAAEERVRTLQEEERwCESLEK 1953
Cdd:PRK03918   685 LEKRREEIKKTLEKLKEELEerEKAKKELEKLEKALERVEELREKVKKYKALLK-ERALSK 744
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 275-590 8.67e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 8.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  275 LERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELYAEIDKapdESPYIGKSRYK 354
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEK---EIERLKETIIK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  355 RNMFATESYIIDSAQAVQIKKMEpdeqlrndhmnlRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEF 434
Cdd:TIGR04523  438 NNSEIKDLTNQDSVKELIIKNLD------------NTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  435 KQLEEAIQ-LKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSkDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRL 513
Cdd:TIGR04523  506 KELEEKVKdLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF-ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQ 584

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  514 DEILSRIAKETEEIKDLEEQLT---------EGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETL 584
Cdd:TIGR04523  585 EEKQELIDQKEKEKKDLIKEIEekekkisslEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEI 664


                   ....*.
gi 2462622367  585 LQRLTE 590
Cdd:TIGR04523  665 IKKIKE 670
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1735-2095 1.02e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 L-NLAKQDLLHTTKHQDV--LLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQR---L 1888
Cdd:TIGR04523  203 LsNLKKKIQKNKSLESQIseLKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQnnkK 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1889 QKERESEESKLETSKVTLKEQQHQ-----LEKELTDQKSKLDQVLSKVLAAEERVRTLQEEerwCESLEKTLSQTKRQLS 1963
Cdd:TIGR04523  283 IKELEKQLNQLKSEISDLNNQKEQdwnkeLKSELKNQEKKLEEIQNQISQNNKIISQLNEQ---ISQLKKELTNSESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1964 EREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEA-LKIQRSQLEKNLLMANQKDLERRQMEIS 2042
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKdEQIKKLQQEKELLEKEIERLKETIIKNN 439

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 2043 DAMRTLKSEvKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENL 2095
Cdd:TIGR04523  440 SEIKDLTNQ-DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491
mukB PRK04863
chromosome partition protein MukB;
401-677 1.26e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.19  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  401 DKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLE--LQMEKQKQEIAGKQKEIKDLQIAIDSL 478
Cdd:PRK04863   834 DPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnlLADETLADRVEEIREQLDEAEEAKRFV 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  479 DSKDPKHSHMKAQKS---GKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIK--------DLEEQLTEGQiAANEALKK 547
Cdd:PRK04863   914 QQHGNALAQLEPIVSvlqSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQrrahfsyeDAAEMLAKNS-DLNEKLRQ 992

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  548 DLEgvisGLQEYLGTIKGQATQAQNECRK-------LRDEKETLLQRLTEVEQERDQLEIVAmdAENMRKELAELESALQ 620
Cdd:PRK04863   993 RLE----QAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLGVPA--DSGAEERARARRDELH 1066

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  621 EQhevnasLQQTQGDLSAyeaeLEARLNLRDAEANQLKEELEKVTR-LTQLEQSALQA 677
Cdd:PRK04863  1067 AR------LSANRSRRNQ----LEKQLTFCEAEMDNLTKKLRKLERdYHEMREQVVNA 1114
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1253-2012 1.30e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 54.03  E-value: 1.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1253 HHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKK----SLECEVEELHRTVQKRQQQKDF 1328
Cdd:pfam01576   35 HQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEersqQLQNEKKKMQQHIQDLEEQLDE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1329 IDGNVESLMTE-LEIEKSLKHHEDIVDEIECIEKTLLKRRSELRE-----ADRLLAEAESELSCTKEKTKNAVeKFTDAK 1402
Cdd:pfam01576  115 EEAARQKLQLEkVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEErisefTSNLAEEEEKAKSLSKLKNKHEA-MISDLE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1403 RSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEEL 1482
Cdd:pfam01576  194 ERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQI 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1483 QKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEA 1562
Cdd:pfam01576  274 SELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQK 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1563 LRLGETEVTEKCNHIREVKSLLEE----LSFQKGELNVQI---SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKN 1635
Cdd:pfam01576  354 HTQALEELTEQLEQAKRNKANLEKakqaLESENAELQAELrtlQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAE 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1636 ILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQS 1715
Cdd:pfam01576  434 KLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKR 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1716 CVEclsKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQ 1795
Cdd:pfam01576  514 NVE---RQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLD 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1796 EKREAVNSLQEelanvqdhlnlaKQdllhttKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 1875
Cdd:pfam01576  591 HQRQLVSNLEK------------KQ------KKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAK 652

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1876 LKLvqqemmfQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVlaaEERVRTLQEEERWCESLEKTL 1955
Cdd:pfam01576  653 EEL-------ERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQL---EELEDELQATEDAKLRLEVNM 722

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 1956 ----SQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLK 2012
Cdd:pfam01576  723 qalkAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELE 783
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1654-2138 1.31e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1654 HDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLqekcdi 1733
Cdd:PRK02224   246 HEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREEL------ 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1734 wEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 1813
Cdd:PRK02224   320 -EDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1814 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDIsewanrfedcqKEEETKqqqLQVLQNEIEENklklvqqemmfQRLQKE-- 1891
Cdd:PRK02224   399 RFGDAPVDLGNAEDFLEELREERDELRERE-----------AELEAT---LRTARERVEEA-----------EALLEAgk 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1892 -----RESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVlaaeERVRTLQEEERWCESLEKTLSQTKRQLSERE 1966
Cdd:PRK02224   454 cpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERL----ERAEDLVEAEDRIERLEERREDLEELIAERR 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1967 QQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEK---QVASL---KEALKIQRSQLEK-----NLLMANQKDLE 2035
Cdd:PRK02224   530 ETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEareEVAELnskLAELKERIESLERirtllAAIADAEDEIE 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2036 RRQMEisdamRTLKSEVKDEIRTSLKNLNQFLPELPAD-----LEAILERNENLEGELESLKENLPFTMNEgpfEEKLNF 2110
Cdd:PRK02224   610 RLREK-----REALAELNDERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREE---RDDLQA 681

                          490       500
                   ....*....|....*....|....*...
gi 2462622367 2111 SQVHIMDEHWRGEALREKLRHREDRLKA 2138
Cdd:PRK02224   682 EIGAVENELEELEELRERREALENRVEA 709
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
245-756 1.37e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  245 RSLESLEGQPVTTQDRQEAFERfSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEeamlqkqsCEEL 324
Cdd:PRK03918   245 KELESLEGSKRKLEEKIRELEE-RIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE--------IEKR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  325 KSDLNTK-NELYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPldtqlEDKE 403
Cdd:PRK03918   316 LSRLEEEiNGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP-----EKLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  404 KKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDL------ELQMEKQKQEIAGKQKEIKDLQIAIDS 477
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrELTEEHRKELLEEYTAELKRIEKELKE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  478 LDSKDPKhshmkaqksgkeqqldiMNKQYQQLESRLDEI--LSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISG 555
Cdd:PRK03918   471 IEEKERK-----------------LRKELRELEKVLKKEseLIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEK 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  556 LQEYLGTIKGQATQAqNECRKLRDEKETLLQRLTEVEQERDQL-----EIVAMDAENMRKELAELESALQEQHEvnaslq 630
Cdd:PRK03918   534 LIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEELAELlkeleELGFESVEELEERLKELEPFYNEYLE------ 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  631 qtqgdLSAYEAELEARLNLRDAEANQLKEELEKVTRLtqleqSALQAELEKERQALKNALGKAQFSE------EKEQENS 704
Cdd:PRK03918   607 -----LKDAEKELEREEKELKKLEEELDKAFEELAET-----EKRLEELRKELEELEKKYSEEEYEElreeylELSRELA 676

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367  705 ELHAKLKHLQDDNNLLKQQLKDFQNHL---NHVVDGLVRPEEVAARVDELRRKLK 756
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEELeerEKAKKELEKLEKALERVEELREKVK 731
PTZ00121 PTZ00121
MAEBL; Provisional
 1289-2050 1.37e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.99  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1289 KEMEEL--HHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESL----MTELEIEKSLKHHEDIVDEIECIEKT 1362
Cdd:PTZ00121  1027 EKIEELteYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYkdfdFDAKEDNRADEATEEAFGKAEEAKKT 1106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1363 LLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSllqTESDAEELERRAQET-AVNLVKADQQLRSLQADAK 1441
Cdd:PTZ00121  1107 ETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA---EDAKRVEIARKAEDArKAEEARKAEDAKKAEAARK 1183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1442 DLEQHKIKQEEILKEINKIVAAKDSDfqclskkKEKLTEELQKLQ--KDIEMAERNEdhhlQVLKESEvllQAKRAELEK 1519
Cdd:PTZ00121  1184 AEEVRKAEELRKAEDARKAEAARKAE-------EERKAEEARKAEdaKKAEAVKKAE----EAKKDAE---EAKKAEEER 1249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1520 LKSQVTSQQQEMAV--LDRQLGHKKEELHllQGSMVQAKADLQEALRLGETEVTEKCNHIR----------EVKSLLEEL 1587
Cdd:PTZ00121  1250 NNEEIRKFEEARMAhfARRQAAIKAEEAR--KADELKKAEEKKKADEAKKAEEKKKADEAKkkaeeakkadEAKKKAEEA 1327

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1588 SFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMS---KHKTELKNILDMLQLENHE------LQGLKLQHDQRV 1658
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaeKKKEEAKKKADAAKKKAEEkkkadeAKKKAEEDKKKA 1407

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1659 SELEKTQVAVLEEKLELENLQQI--SQQQKGEIEWQKQLLERDKREIERMTAES---RALQSCVECLSKEKEDLQEKCDI 1733
Cdd:PTZ00121  1408 DELKKAAAAKKKADEAKKKAEEKkkADEAKKKAEEAKKADEAKKKAEEAKKAEEakkKAEEAKKADEAKKKAEEAKKADE 1487

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1734 WEKKLAQTKRvlaAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQ----EELA 1809
Cdd:PTZ00121  1488 AKKKAEEAKK---KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEElkkaEEKK 1564

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1810 NVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDI----SEWANRFEDCQKEEETKQQQLQVLQneiEENKLKLVQQEMMF 1885
Cdd:PTZ00121  1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMklyeEEKKMKAEEAKKAEEAKIKAEELKK---AEEEKKKVEQLKKK 1641

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1886 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSER 1965
Cdd:PTZ00121  1642 EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEEL 1721

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1966 EQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIqRSQLEKNLLMANQKDLERRQMEISDAM 2045
Cdd:PTZ00121  1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI-RKEKEAVIEEELDEEDEKRRMEVDKKI 1800


                   ....*
gi 2462622367 2046 RTLKS 2050
Cdd:PTZ00121  1801 KDIFD 1805
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1359-1570 1.38e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.48  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1359 IEKTLLKRRSELREADRLLAE--AESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSL 1436
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1437 QADA--KDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEdhhLQVLKESEVLLQAKR 1514
Cdd:COG3206    260 LQSPviQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAE---LEALQAREASLQAQL 336

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 1515 AELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKadLQEALRLGETEV 1570
Cdd:COG3206    337 AQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR--LAEALTVGNVRV 390
mukB PRK04863
chromosome partition protein MukB;
387-753 1.77e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.42  E-value: 1.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  387 MNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEAL--------------DLEL 452
Cdd:PRK04863   283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALrqqekieryqadleELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  453 QMEKQKQEIAGKQKEIKDLQI----AIDSLDSkdpkhshMKAQKSGKEQQLDIMNK---QYQQLESRLDEILSRIAKETE 525
Cdd:PRK04863   363 RLEEQNEVVEEADEQQEENEAraeaAEEEVDE-------LKSQLADYQQALDVQQTraiQYQQAVQALERAKQLCGLPDL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  526 EIKDLEEQLTEGQIAANEALKK--DLEGVISGLQEylgtIKGQATQAQNECRKLRDE--KETLLQRLTEVEQERDQLEIV 601
Cdd:PRK04863   436 TADNAEDWLEEFQAKEQEATEEllSLEQKLSVAQA----AHSQFEQAYQLVRKIAGEvsRSEAWDVARELLRRLREQRHL 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  602 AMDAENMRKELAELESALQEQHEVNASLQQTQGDLSA---YEAELEARLNLRDAEANQLKEELEKVtRLTQLEQSALQAE 678
Cdd:PRK04863   512 AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKnldDEDELEQLQEELEARLESLSESVSEA-RERRMALRQQLEQ 590

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462622367  679 LEKERQALknalgkaqfsEEKEQENSELHAKLKHLQD---DNNLLKQQLKDF-QNHLNHVVDGLVRPEEVAARVDELRR 753
Cdd:PRK04863   591 LQARIQRL----------AARAPAWLAAQDALARLREqsgEEFEDSQDVTEYmQQLLERERELTVERDELAARKQALDE 659
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 641-1561 1.90e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 1.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  641 AELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQA---ELEKERQALKNALGKAQFSEEKEQEN-SELHAKLKHLQDD 716
Cdd:TIGR02168  196 NELERQLKSLERQAEKAERYKELKAELRELELALLVLrleELREELEELQEELKEAEEELEELTAElQELEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  717 NNLLKQQLKDFQNHLNhvvdglvrpeEVAARVDELRRKLKlgtgemnihspsdVLGKSLADLQKQFSEILArskwERDEA 796
Cdd:TIGR02168  276 VSELEEEIEELQKELY----------ALANEISRLEQQKQ-------------ILRERLANLERQLEELEA----QLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  797 QVRERKLQEEMALQQEKLATGQEEFrqACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEAD 876
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEEL--ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  877 EEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKklkkavatsdklatAELTIAKDQLKSLHGTVmkinQERAEELQE 956
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL--------------EELEEELEELQEELERL----EEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  957 AERFSRKAAQAAR-DLTRAEAEIELLQNLLRQKGEQFR------LEMEKTGVGTGANSQVLEIEklnetmERQRTEI--- 1026
Cdd:TIGR02168  469 ELEEAEQALDAAErELAQLQARLDSLERLQENLEGFSEgvkallKNQSGLSGILGVLSELISVD------EGYEAAIeaa 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1027 --ARLQNVLDltgsdnkGGFENVLEEIAELRRevsyqndyissmadpfKRRGYWYFMPPPPSSKVSSHSSQA-TKDSGVG 1103
Cdd:TIGR02168  543 lgGRLQAVVV-------ENLNAAKKAIAFLKQ----------------NELGRVTFLPLDSIKGTEIQGNDReILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1104 LKYSASTPVrkprpgqqdgKEGSQPPPASGYWvyspirsgLHKLFPSRDADSGGDSQEESelddqeeppfvpPPGYMMYT 1183
Cdd:TIGR02168  600 FLGVAKDLV----------KFDPKLRKALSYL--------LGGVLVVDDLDNALELAKKL------------RPGYRIVT 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1184 vlPDGSPVpqgmalyapppplpnnsrplTPGTVVYGpppagapmvyGPPPPNFSIpfipmgvlhcnvpehHNLENEVSRL 1263
Cdd:TIGR02168  650 --LDGDLV--------------------RPGGVITG----------GSAKTNSSI---------------LERRREIEEL 682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1264 edimqhlkskkreerwmraskrqsEKEMEELHHNIDDLLQEKKSLECEVEELhrTVQKRQQQKDFIDGNVESLMTELEIE 1343
Cdd:TIGR02168  683 ------------------------EEKIEELEEKIAELEKALAELRKELEEL--EEELEQLRKELEELSRQISALRKDLA 736

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1344 KSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETA 1423
Cdd:TIGR02168  737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN 816

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1424 VNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVaakdsdfqclskkkEKLTEELQKLQKDIEMAERNEDHHLQVL 1503
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI--------------ESLAAEIEELEELIEELESELEALLNER 882

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367 1504 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQE 1561
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
418-989 1.93e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 1.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  418 DEIEKAEQQILRATEEFKQLEEAIQ--LKKEAlDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHS-------HM 488
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEkfIKRTE-NIEELIKEKEKELEEVLREINEISSELPELREELEKLEkevkeleEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  489 KAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEgqiaaNEALKKDLEGVISgLQEYLGTIKGQAT 568
Cdd:PRK03918   237 KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-----LKELKEKAEEYIK-LSEFYEEYLDELR 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  569 QAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELES---ALQEQHEVNASLQQTQGDLSAYEAE-LE 644
Cdd:PRK03918   311 EIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErheLYEEAKAKKEELERLKKRLTGLTPEkLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  645 ARLNLRDAEANQLKEELEKVT-RLTQLEQSAlqAELEKERQALKNALGK-----AQFSEEKEQE-NSELHAKLKHLQDDN 717
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITaRIGELKKEI--KELKKAIEELKKAKGKcpvcgRELTEEHRKElLEEYTAELKRIEKEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  718 NLLKQQLKDFQNHLNHVVDGLVRPEEVAA--RVDELRRKLKLGTGEMNIHSPSDVlGKSLADLQKQFSEILARSKWERDE 795
Cdd:PRK03918   469 KEIEEKERKLRKELRELEKVLKKESELIKlkELAEQLKELEEKLKKYNLEELEKK-AEEYEKLKEKLIKLKGEIKSLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  796 AQvRERKLQEEMALQQEKLATGQEEfRQACERALEARMNFDKRQHEARIQQME------NEIHYLQENLKSMEEIQGLTD 869
Cdd:PRK03918   548 LE-KLEELKKKLAELEKKLDELEEE-LAELLKELEELGFESVEELEERLKELEpfyneyLELKDAEKELEREEKELKKLE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  870 LQLQEADEEKERILAQLRELEKK-KKLEDAKSQEQVFGLDKELKKLKKAVATsdklATAELTIAKDQLKSLHGTVMKINQ 948
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKElEELEKKYSEEEYEELREEYLELSRELAG----LRAELEELEKRREEIKKTLEKLKE 701

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2462622367  949 ERaEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKG 989
Cdd:PRK03918   702 EL-EEREKAKKELEKLEKALERVEELREKVKKYKALLKERA 741
mukB PRK04863
chromosome partition protein MukB;
578-901 2.02e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.42  E-value: 2.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  578 RDEKETLLQRLTEVEQE----RDQLEIVAMDAENMRKELAEL---ESALQEQHE--------VNASLQQT------QGDL 636
Cdd:PRK04863   278 ANERRVHLEEALELRRElytsRRQLAAEQYRLVEMARELAELneaESDLEQDYQaasdhlnlVQTALRQQekieryQADL 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  637 SAYEAELEARLNLRdAEANQLKEELEKVTRLTQLEQSALQAELEKERQAL-------------KNALGKAQ-------FS 696
Cdd:PRK04863   358 EELEERLEEQNEVV-EEADEQQEENEARAEAAEEEVDELKSQLADYQQALdvqqtraiqyqqaVQALERAKqlcglpdLT 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  697 EEKEQE-NSELHAKLKHLQDDNNLLKQQLKDFQNHLNH----------VVDGLVRPEE----------------VAARVD 749
Cdd:PRK04863   437 ADNAEDwLEEFQAKEQEATEELLSLEQKLSVAQAAHSQfeqayqlvrkIAGEVSRSEAwdvarellrrlreqrhLAEQLQ 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  750 ELRRKLKLGTGEMNIHspsdvlgkslADLQKQFSEILARSKWERDEAQVRERkLQEEmalQQEKLATGQEEFRQACERAL 829
Cdd:PRK04863   517 QLRMRLSELEQRLRQQ----------QRAERLLAEFCKRLGKNLDDEDELEQ-LQEE---LEARLESLSESVSEARERRM 582

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367  830 EARMNFDkrQHEARIQQMEN---EIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLREL-EKKKKLEDAKSQ 901
Cdd:PRK04863   583 ALRQQLE--QLQARIQRLAArapAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELtVERDELAARKQA 656
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1473-2050 2.07e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 2.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1473 KKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVtsqqQEMAVLDRQLGHKKEELHLLQGSM 1552
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV----KELEELKEEIEELEKELESLEGSK 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1553 VQAKADLQEalrlgetevTEKcnHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIekeeeNLQVVLRQMSKHKTE 1632
Cdd:PRK03918   255 RKLEEKIRE---------LEE--RIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYE-----EYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1633 LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMtaesra 1712
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKE------ 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1713 lqscVECLSKEKEDLQEKcdiwEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKL--SLHNDISAM 1790
Cdd:PRK03918   393 ----LEELEKAKEEIEEE----ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELleEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1791 QQQLQEKREAVNSLQEELANVQDHLNLAKQdLLHTTKHQDVLLSEQTRLQK----DISEWANRFEDCQKEEETKQQQLQV 1866
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEKVLKKESE-LIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1867 LQNEIEENKLklvqqemmfqrLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEER 1946
Cdd:PRK03918   544 LKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1947 WCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERK-KAEKQVASLKEALKIQRSQLEKn 2025
Cdd:PRK03918   613 ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYlELSRELAGLRAELEELEKRREE- 691

                          570       580
                   ....*....|....*....|....*
gi 2462622367 2026 lLMANQKDLERRQMEISDAMRTLKS 2050
Cdd:PRK03918   692 -IKKTLEKLKEELEEREKAKKELEK 715
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1256-1856 2.53e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVES 1335
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKED 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1336 LmtELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELScTKEKTKNAVEK-----------FTDAKRS 1404
Cdd:TIGR02169  446 K--ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA-EAEAQARASEErvrggraveevLKASIQG 522

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1405 LLQTESDAEELERRAQ----------------ETAVNLVKADQQLRSLQAD-AKDLEQHKIKQEEILKEINKIVAAKDS- 1466
Cdd:TIGR02169  523 VHGTVAQLGSVGERYAtaievaagnrlnnvvvEDDAVAKEAIELLKRRKAGrATFLPLNKMRDERRDLSILSEDGVIGFa 602

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1467 -DFQCLSKKKEKLTEELQK---LQKDIEMAERNEDHHLQVLKESEVL----------LQAKRAEL--EKLKSQVTSQQQE 1530
Cdd:TIGR02169  603 vDLVEFDPKYEPAFKYVFGdtlVVEDIEAARRLMGKYRMVTLEGELFeksgamtggsRAPRGGILfsRSEPAELQRLRER 682

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1531 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRlgetEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ 1610
Cdd:TIGR02169  683 LEGLKRELSSLQSELRRIENRLDELSQELSDASR----KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1611 EIEKEEENLQVVLRQMSKHKTELKNILDMLQLE-----NHELQGLKLQH---DQRVSELEKTQVAVLEEKLELENLQQIS 1682
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKLEEEVsriEARLREIEQKLNRLTLEKEYLEKEIQEL 838

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1683 QQQKGEIEWQK----QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSN 1758
Cdd:TIGR02169  839 QEQRIDLKEQIksieKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1759 LEKLELNVRKLQQELDQLNRDKLSLHNDISAMQ--QQLQEKREAVnslQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQ 1836
Cdd:TIGR02169  919 LSELKAKLEALEEELSEIEDPKGEDEEIPEEELslEDVQAELQRV---EEEIRALEPVNMLAIQEYEEVLKRLDELKEKR 995

                          650       660
                   ....*....|....*....|
gi 2462622367 1837 TRLQKDISEWANRFEDCQKE 1856
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1378-1567 2.59e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 52.14  E-value: 2.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1378 AEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKE- 1456
Cdd:COG3883     12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEr 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1457 -------------INKIVAAKD-SDF-------QCLSKKKEKLTEELQKLQKDIEMAERNedhhlqvLKESEVLLQAKRA 1515
Cdd:COG3883     92 aralyrsggsvsyLDVLLGSESfSDFldrlsalSKIADADADLLEELKADKAELEAKKAE-------LEAKLAELEALKA 164

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462622367 1516 ELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGE 1567
Cdd:COG3883    165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1288-1813 2.73e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 2.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1288 EKEMEELHHNIDDLLQEKKSLECEVEELH----RTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTL 1363
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEeqreQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1364 LKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLlqtESDAEELERRAQETAVNLVKADQQLRSLQADAKDL 1443
Cdd:PRK02224   278 AEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREEL---EDRDEELRDRLEECRVAAQAHNEEAESLREDADDL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1444 EQHKIKQEEILKEInkivaakDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQ 1523
Cdd:PRK02224   355 EERAEELREEAAEL-------ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRER 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1524 VTSQQQEMAVLDRQLgHKKEELhLLQGSMVQAKADLQEALRLGETEvtEKCNHIREVKSLLEELSFQKGELNVQIsERKT 1603
Cdd:PRK02224   428 EAELEATLRTARERV-EEAEAL-LEAGKCPECGQPVEGSPHVETIE--EDRERVEELEAELEDLEEEVEEVEERL-ERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1604 QLTLIKQEIEKEEENLQVVLRQMSKHKTELKNilDMLQLEnhELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQ 1683
Cdd:PRK02224   503 DLVEAEDRIERLEERREDLEELIAERRETIEE--KRERAE--ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELN 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1684 QQKGEIEWQKQLLERdkreIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLA---QTKRVLAAAEENSKME--QSN 1758
Cdd:PRK02224   579 SKLAELKERIESLER----IRTLLAAIADAEDEIERLREKREALAELNDERRERLAekrERKRELEAEFDEARIEeaRED 654

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 1759 LEKLELNVRKLQQELDQLNRDKLSLHNDISAMQ------QQLQEKREAVNSLQEELANVQD 1813
Cdd:PRK02224   655 KERAEEYLEQVEEKLDELREERDDLQAEIGAVEneleelEELRERREALENRVEALEALYD 715
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
422-1031 3.01e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.61  E-value: 3.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  422 KAEQQILRATEEFKQLEEAiqlKKEALDLELQMEkQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKsgkeqqldi 501
Cdd:COG4913    222 DTFEAADALVEHFDDLERA---HEALEDAREQIE-LLEPIRELAERYAAARERLAELEYLRAALRLWFAQR--------- 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  502 mnkQYQQLESRLDEILSRIAKETEEIKDLEEQLTEgqiaanealkkdLEGVISGLQEYLGTIKGQA-TQAQNECRKLRDE 580
Cdd:COG4913    289 ---RLELLEAELEELRAELARLEAELERLEARLDA------------LREELDELEAQIRGNGGDRlEQLEREIERLERE 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  581 KETLLQRLTEVEQerdQLEIVAMDAENMRKELAELESALQEQhevnaslqqtQGDLSAYEAELEARLNLRDAEANQLKEE 660
Cdd:COG4913    354 LEERERRRARLEA---LLAALGLPLPASAEEFAALRAEAAAL----------LEALEEELEALEEALAEAEAALRDLRRE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  661 LEKVTR-LTQLEQ--SALQAELEKERQALKNALGKAQfseekeqenSELH--AKLKHLQDDNnllkqqlKDFQNHLNHVV 735
Cdd:COG4913    421 LRELEAeIASLERrkSNIPARLLALRDALAEALGLDE---------AELPfvGELIEVRPEE-------ERWRGAIERVL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  736 DG-----LVRPE---EVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADlqkqfsEILARSKWERDEAQVR-ERKLQEE 806
Cdd:COG4913    485 GGfaltlLVPPEhyaAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPD------SLAGKLDFKPHPFRAWlEAELGRR 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  807 MALQQeklATGQEEFRQAcERAL--EARMNFDKRQHEARIQQMENEIHYL-QENLKSMEEIQGltdlQLQEADEEKERIL 883
Cdd:COG4913    559 FDYVC---VDSPEELRRH-PRAItrAGQVKGNGTRHEKDDRRRIRSRYVLgFDNRAKLAALEA----ELAELEEELAEAE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  884 AQLRELEKKKK-LEDAKSQEQVFGLDKELKKLKKAVATsdklATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSR 962
Cdd:COG4913    631 ERLEALEAELDaLQERREALQRLAEYSWDEIDVASAER----EIAELEAELERLDASSDDLAALEEQLEELEAELEELEE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  963 KAAQAARDLTRAEAEIELLQNLLRQK-------------------GEQFRLEMEKTGVGTGANSQVLEIEKLNETMERQR 1023
Cdd:COG4913    707 ELDELKGEIGRLEKELEQAEEELDELqdrleaaedlarlelrallEERFAAALGDAVERELRENLEERIDALRARLNRAE 786


                   ....*...
gi 2462622367 1024 TEIARLQN 1031
Cdd:COG4913    787 EELERAMR 794
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1460-2093 3.17e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 3.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1460 IVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLG 1539
Cdd:TIGR04523   27 IANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLS 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1540 HKKEELHLLQGSMVQAK---ADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEE 1616
Cdd:TIGR04523  107 KINSEIKNDKEQKNKLEvelNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1617 ENLQVVLRQMSKHKTELKNILDMLQLENH---ELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQK 1693
Cdd:TIGR04523  187 KNIDKIKNKLLKLELLLSNLKKKIQKNKSlesQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIK 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1694 QLLERDKREIERMTAESRALQSCVECLSKEKEDL-QEKCDIWEKKLaqtKRVLAAAEENSKMEQSNLEKLELNVRKLQQE 1772
Cdd:TIGR04523  267 KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnNQKEQDWNKEL---KSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1773 LDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEElanvqdhlnlaKQDLLHTTKHqdvLLSEQTRLQKDISEWANRFED 1852
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE-----------NQSYKQEIKN---LESQINDLESKIQNQEKLNQQ 409

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1853 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEE---SKLETSKVTLKEQQHQLEKELTDQKSKLDQVLS 1929
Cdd:TIGR04523  410 KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1930 KVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQL----VEKSGELLALQKEADSMraDFSLLRNQFLTERKKAE 2005
Cdd:TIGR04523  490 ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekKEKESKISDLEDELNKD--DFELKKENLEKEIDEKN 567

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2006 KQVASLKEalkiqrsqleknllmaNQKDLERRQMEISDAMRTLKSEVKDeIRTSLKNLNQFLPELPADLEAILERNENLE 2085
Cdd:TIGR04523  568 KEIEELKQ----------------TQKSLKKKQEEKQELIDQKEKEKKD-LIKEIEEKEKKISSLEKELEKAKKENEKLS 630


                   ....*...
gi 2462622367 2086 GELESLKE 2093
Cdd:TIGR04523  631 SIIKNIKS 638
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 440-709 3.56e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 52.36  E-value: 3.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  440 AIQLKKEALDLELQMEKQKQEIAgkQKEIKD-LQIAIDSLDskDPKHSHMKAQksgkeqqldimnkQYQQ----LESRLD 514
Cdd:PRK10929    20 ATAPDEKQITQELEQAKAAKTPA--QAEIVEaLQSALNWLE--ERKGSLERAK-------------QYQQvidnFPKLSA 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  515 EILSRIAKETEEIKDLEEQLTegqiaaNEALKKDLEGVISGLQEylgtIKGQATQAQNECRKLRDEKETLLQRLTEVeqe 594
Cdd:PRK10929    83 ELRQQLNNERDEPRSVPPNMS------TDALEQEILQVSSQLLE----KSRQAQQEQDRAREISDSLSQLPQQQTEA--- 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  595 rdqleivamdaenmRKELAELESALQEQHEVNASLQQTQgdlsayEAELEARLNLRDAEANQLkeELEKVTRLTQLEQSA 674
Cdd:PRK10929   150 --------------RRQLNEIERRLQTLGTPNTPLAQAQ------LTALQAESAALKALVDEL--ELAQLSANNRQELAR 207

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462622367  675 LQAELEKER--------QALKNALgKAQFSEEKEQ--ENSELHAK 709
Cdd:PRK10929   208 LRSELAKKRsqqldaylQALRNQL-NSQRQREAERalESTELLAE 251
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1451-1960 3.74e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 3.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1451 EEILKEINKIvaakDSDFQCLSKKKEKLTEELQKLQK---DIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQ 1527
Cdd:PRK03918   203 EEVLREINEI----SSELPELREELEKLEKEVKELEElkeEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1528 QQEMAVLdRQLGHKKEELHLLQGSMVQAKADLQEaLRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTl 1607
Cdd:PRK03918   279 EEKVKEL-KELKEKAEEYIKLSEFYEEYLDELRE-IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLE- 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1608 IKQEIEKEEENLQVVLRQMSKHKTELKNI-LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQK 1686
Cdd:PRK03918   356 ELEERHELYEEAKAKKEELERLKKRLTGLtPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1687 GEI---------EWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLqEKCDIWEKKLAQTKRVLAAAEE-NSKMEQ 1756
Cdd:PRK03918   436 GKCpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKELAEQLKElEEKLKK 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1757 SNLEKLELN---VRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREavnsLQEELANVQDHL-NLAKQDLLHTTKHQDVL 1832
Cdd:PRK03918   515 YNLEELEKKaeeYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAE----LEKKLDELEEELaELLKELEELGFESVEEL 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1833 LSEQTRLQKDISEWaNRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKE--------RESEESKLETSKV 1904
Cdd:PRK03918   591 EERLKELEPFYNEY-LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEleelekkySEEEYEELREEYL 669

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 1905 TLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKR 1960
Cdd:PRK03918   670 ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1547-1924 5.44e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 51.43  E-value: 5.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1547 LLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLtlikqeiekeEENLQVVLRQM 1626
Cdd:pfam07888   31 LLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEEL----------RQSREKHEELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1627 SKHKtELKNILDMLQLENHELQGLKLQHDQRVSELEktqvavleekleleNLQQISQQQKGEIEWQkqlLERDKREIERM 1706
Cdd:pfam07888  101 EKYK-ELSASSEELSEEKDALLAQRAAHEARIRELE--------------EDIKTLTQRVLERETE---LERMKERAKKA 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1707 TAESRALQScveclskEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKL---SL 1783
Cdd:pfam07888  163 GAQRKEEEA-------ERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAeneAL 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1784 HNDISAMQQQLQEKREAVNSLQEELANVqdhlnLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQ--KEEETKQ 1861
Cdd:pfam07888  236 LEELRSLQERLNASERKVEGLGEELSSM-----AAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARwaQERETLQ 310

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 1862 QQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKL 1924
Cdd:pfam07888  311 QSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASL 373
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1760-2141 7.93e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.49  E-value: 7.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1760 EKLELNVRKLQQELDQLN-RDKLSLHND-ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTK---HQDVL-- 1832
Cdd:COG3096    279 ERRELSERALELRRELFGaRRQLAEEQYrLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKierYQEDLee 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1833 LSEQTRLQKDISEWAN--------RFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERE-SEESKLEtsk 1903
Cdd:COG3096    359 LTERLEEQEEVVEEAAeqlaeaeaRLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARAlCGLPDLT--- 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1904 vtlkeqQHQLEKELTDQKSKLDQVLSKVLAAEERVR----TLQEEERWCESLEKTLSQTKR-QLSEREQQLVEKSGELLA 1978
Cdd:COG3096    436 ------PENAEDYLAAFRAKEQQATEEVLELEQKLSvadaARRQFEKAYELVCKIAGEVERsQAWQTARELLRRYRSQQA 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1979 LQKEADSMRADFSLLRnQFLTERKKAEKQVASLKEALKIQRSQLEknLLMANQKDLERRQMEISDAMRTLkSEVKDEIRT 2058
Cdd:COG3096    510 LAQRLQQLRAQLAELE-QRLRQQQNAERLLEEFCQRIGQQLDAAE--ELEELLAELEAQLEELEEQAAEA-VEQRSELRQ 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2059 SLKNLNQFLPELPA------DLEAILERNENLEGE-LESLkenlpftmnegpfEEKLNFSQVHIMDEHwRGEALREKLRH 2131
Cdd:COG3096    586 QLEQLRARIKELAArapawlAAQDALERLREQSGEaLADS-------------QEVTAAMQQLLERER-EATVERDELAA 651

                          410
                   ....*....|
gi 2462622367 2132 REDRLKAQLR 2141
Cdd:COG3096    652 RKQALESQIE 661
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1791-2071 9.32e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 9.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1791 QQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVL--LSEQTRLQKDISEWanrfedcQKEEETKQQQLQvlq 1868
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALqrLAEYSWDEIDVASA-------EREIAELEAELE--- 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1869 nEIEENKLKLVQQEMMFQRLQKERESEESKLETskvtLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQE---EE 1945
Cdd:COG4913    679 -RLDASSDDLAALEEQLEELEAELEELEEELDE----LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRallEE 753

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1946 RWCESL-EKTLSQTKRQLSEREQQLVEKsgellaLQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIqRSQLEK 2024
Cdd:COG4913    754 RFAAALgDAVERELRENLEERIDALRAR------LNRAEEELERAMRAFNREWPAETADLDADLESLPEYLAL-LDRLEE 826

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 2025 NLLMANQKDLERRQMEISDAMRT-LKSEVKDEIRT---SLKNLNQFLPELP 2071
Cdd:COG4913    827 DGLPEYEERFKELLNENSIEFVAdLLSKLRRAIREikeRIDPLNDSLKRIP 877
PRK01156 PRK01156
chromosome segregation protein; Provisional
 269-669 1.05e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 51.06  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  269 LEEVERLERDLEKKMIETEELKsKQTRFLEEikNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELyAEIDKAPDESPYI 348
Cdd:PRK01156   331 LSVLQKDYNDYIKKKSRYDDLN-NQILELEG--YEMDYNSYLKSIESLKKKIEEYSKNIERMSAFI-SEILKIQEIDPDA 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  349 GKSRY---KRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHM-NLRGHTPL---DTQLEDKEKKISAAQTRLSELHDEIE 421
Cdd:PRK01156   407 IKKELneiNVKLQDISSKVSSLNQRIRALRENLDELSRNMEMlNGQSVCPVcgtTLGEEKSNHIINHYNEKKSRLEEKIR 486

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  422 KAEQQILRATEEFKQLEEAIQ-LKKEALDlelQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQ-KSGKEQQL 499
Cdd:PRK01156   487 EIEIEVKDIDEKIVDLKKRKEyLESEEIN---KSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRyKSLKLEDL 563

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  500 DIMNKQYQQLESRLDEIlsriaketeEIKDLEEQLTEgqiaaneaLKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRD 579
Cdd:PRK01156   564 DSKRTSWLNALAVISLI---------DIETNRSRSNE--------IKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIEN 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  580 EKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKE 659
Cdd:PRK01156   627 EANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEI 706

                          410
                   ....*....|
gi 2462622367  660 ELEKVTRLTQ 669
Cdd:PRK01156   707 LRTRINELSD 716
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 395-940 1.06e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.99  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAiQLKKEALDLEL------QMEKQKQEIAGKQKEI 468
Cdd:pfam12128  292 LRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDA-DIETAAADQEQlpswqsELENLEERLKALTGKH 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  469 KDLQIAIDSLDSKDPK---------HSHMKAQKSGKEQQLDIMNKQYQQLESRL-DEILSRIAKETEEIKDLEEQLTE-- 536
Cdd:pfam12128  371 QDVTAKYNRRRSKIKEqnnrdiagiKDKLAKIREARDRQLAVAEDDLQALESELrEQLEAGKLEFNEEEYRLKSRLGElk 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  537 ---GQIAANEALKKDLEG---VISGLQEYLGTIKGQATQAQNECRKLRDEKETLL-------QRLTEVEQERDQLEIV-- 601
Cdd:pfam12128  451 lrlNQATATPELLLQLENfdeRIERAREEQEAANAEVERLQSELRQARKRRDQASealrqasRRLEERQSALDELELQlf 530

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  602 ----------------------------------------------------------AMDA-------ENMRKELAELE 616
Cdd:pfam12128  531 pqagtllhflrkeapdweqsigkvispellhrtdldpevwdgsvggelnlygvkldlkRIDVpewaaseEELRERLDKAE 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  617 SALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALgkAQFS 696
Cdd:pfam12128  611 EALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERL--NSLE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  697 EEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVD---GLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGK 773
Cdd:pfam12128  689 AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDaqlALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPD 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  774 SLADLQKQFSEILAR-SKWERDEAQVRE--RKLQEEMALQQEKLATGQEEFRQACER------ALEARMNFDKRQHEARI 844
Cdd:pfam12128  769 VIAKLKREIRTLERKiERIAVRRQEVLRyfDWYQETWLQRRPRLATQLSNIERAISElqqqlaRLIADTKLRRAKLEMER 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  845 QQMENEIHYLQENLKSME-EIQGLTDLQL----QEADEEKERILAQLRELEKKKK--LEDAKSQEQVFGLDKELKKLKKA 917
Cdd:pfam12128  849 KASEKQQVRLSENLRGLRcEMSKLATLKEdansEQAQGSIGERLAQLEDLKLKRDylSESVKKYVEHFKNVIADHSGSGL 928

                          650       660
                   ....*....|....*....|...
gi 2462622367  918 VATSDKLATAELTIAKDQLKSLH 940
Cdd:pfam12128  929 AETWESLREEDHYQNDKGIRLLD 951
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1790-1997 1.09e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1790 MQQQLQEKREAVNS----LQEELANVQDHLNLAKQDLLH-TTKHQDVLLSEQTR-LQKDISEWANRFEDCQKEEETKQQQ 1863
Cdd:COG3206    162 LEQNLELRREEARKalefLEEQLPELRKELEEAEAALEEfRQKNGLVDLSEEAKlLLQQLSELESQLAEARAELAEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1864 LQVLQNEIEENKLKL--VQQEMMFQRLQKERESEESKLETSKVTLKEQqH----QLEKELTDQKSKLDQVLSKVLA-AEE 1936
Cdd:COG3206    242 LAALRAQLGSGPDALpeLLQSPVIQQLRAQLAELEAELAELSARYTPN-HpdviALRAQIAALRAQLQQEAQRILAsLEA 320

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 1937 RVRTLQEEErwcESLEKTLSQTKRQLsereQQLVEKSGELLALQKEADSMRADFSLLRNQF 1997
Cdd:COG3206    321 ELEALQARE---ASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELYESLLQRL 374
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 395-1062 1.30e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQL--EEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQ 472
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  473 ----IAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLtegqiaanealkKD 548
Cdd:TIGR02169  322 erlaKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL------------KD 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  549 LEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAenmRKELAELESalqeqhevnaS 628
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDK---ALEIKKQEW----------K 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  629 LQQTQGDLSAYEAELEarlnlrdaeanQLKEELEKVTRltqlEQSALQ---AELEKERQALKNA-LGKAQFSEEKEQENS 704
Cdd:TIGR02169  457 LEQLAADLSKYEQELY-----------DLKEEYDRVEK----ELSKLQrelAEAEAQARASEERvRGGRAVEEVLKASIQ 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  705 ELHAKLKHL-QDDNNLLKQQLKDFQNHLNHVVdglVRPEEVAARVDELRRKLKLG-------TGEMNIHSPSDVLGKS-- 774
Cdd:TIGR02169  522 GVHGTVAQLgSVGERYATAIEVAAGNRLNNVV---VEDDAVAKEAIELLKRRKAGratflplNKMRDERRDLSILSEDgv 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  775 ------LADLQKQFS---------------------------------EILARS------KWERDEAQVRERKLQEEMAL 809
Cdd:TIGR02169  599 igfavdLVEFDPKYEpafkyvfgdtlvvedieaarrlmgkyrmvtlegELFEKSgamtggSRAPRGGILFSRSEPAELQR 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  810 QQEKLatgqEEFRQACERALEARMNFDKRQHEARIQqmeneihyLQENLKSMEEIQGLTDLQLQEADEEKERILAQLREL 889
Cdd:TIGR02169  679 LRERL----EGLKRELSSLQSELRRIENRLDELSQE--------LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  890 EKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAAR 969
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  970 DLTRAEAEIELLQNLLRQKGEQfRLEMEKtgvgtgansqvlEIEKLNETMERQRTEIARLQN-VLDLTG--SDNKGGFEN 1046
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQ-IKSIEK------------EIENLNGKKEELEEELEELEAaLRDLESrlGDLKKERDE 893

                          730
                   ....*....|....*.
gi 2462622367 1047 VLEEIAELRREVSYQN 1062
Cdd:TIGR02169  894 LEAQLRELERKIEELE 909
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1854-2040 1.39e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1854 QKEEETkQQQLQVLQNEIEENKLKLVQQEMMFQRLQKER-----ESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVL 1928
Cdd:COG3206    168 LRREEA-RKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALR 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1929 SKVLAAEERVRTLQEEERWcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQV 2008
Cdd:COG3206    247 AQLGSGPDALPELLQSPVI-QQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEAL 325

                          170       180       190
                   ....*....|....*....|....*....|..
gi 2462622367 2009 ASLKEALKIQRSQLEKNLLMANQKDLERRQME 2040
Cdd:COG3206    326 QAREASLQAQLAQLEARLAELPELEAELRRLE 357
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1255-2008 1.50e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.36  E-value: 1.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1255 NLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVE 1334
Cdd:pfam02463  301 ELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1335 SLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEE 1414
Cdd:pfam02463  381 LESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1415 LERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAER 1494
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1495 NEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELhllqgsmvqakadlqeaLRLGETEVTEKC 1574
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPL-----------------KSIAVLEIDPIL 603

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1575 NHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIekeeenlqVVLRQMSKHKTELKNILDMLQLENHELQGLKLQH 1654
Cdd:pfam02463  604 NLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA--------KAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL 675

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1655 DQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIW 1734
Cdd:pfam02463  676 LEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKS 755

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELdqlnrdklslhnDISAMQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:pfam02463  756 RLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE------------KLKAQEEELRALEEELKEEAELLEEEQLL 823

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1815 LNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANR-FEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERE 1893
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERlEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELE 903

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1894 SEESKletskvtlKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKS 1973
Cdd:pfam02463  904 EESQK--------LNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKV 975

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2462622367 1974 GELLALQKEADSMRADFSLLRNQFLTERKKAEKQV 2008
Cdd:pfam02463  976 NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRA 1010
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 395-549 1.60e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.38  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEAL-DLELQMEK--QKQEIAGKQKEIKDL 471
Cdd:COG1579     15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIeEVEARIKKyeEQLGNVRNNKEYEAL 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  472 QIAIDSLDSK----DPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKK 547
Cdd:COG1579     95 QKEIESLKRRisdlEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174


                   ..
gi 2462622367  548 DL 549
Cdd:COG1579    175 EL 176
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1281-1494 1.64e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1281 RASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTEL-EIEKSLKHHEDIVDEieci 1359
Cdd:COG4942     33 QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIaELRAELEAQKEELAE---- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1360 ektLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQT-ESDAEELERRAQETAVNLVKADQQLRSLQA 1438
Cdd:COG4942    109 ---LLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEElRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 1439 DAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAER 1494
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 126-167 1.66e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 43.77  E-value: 1.66e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2462622367  126 KLEVLNLSYNLIGKIEKLDKLLKLRELNLSYN-KISKIEGIEN 167
Cdd:pfam12799    2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 420-993 1.72e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.35  E-value: 1.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  420 IEKAEQQILRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIK-------DLQIAIDSLDSKDPKHSHMKAQK 492
Cdd:TIGR00618  224 LEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRaqeavleETQERINRARKAAPLAAHIKAVT 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  493 SGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEylgtIKGQATQAQN 572
Cdd:TIGR00618  304 QIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIRE----ISCQQHTLTQ 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  573 ECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDA 652
Cdd:TIGR00618  380 HIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKI 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  653 EANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAK-------------LKHLQDDNNL 719
Cdd:TIGR00618  460 HLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPArqdidnpgpltrrMQRGEQTYAQ 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  720 LKQQLKDFQNHLNHVVDGLVRPEEVAARVDElrRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVR 799
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKQRASLKEQMQEIQQ--SFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  800 ERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQM---ENEIHYLQENLKSMEEIQGLTDlQLQEAD 876
Cdd:TIGR00618  618 LRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALsirVLPKELLASRQLALQKMQSEKE-QLTYWK 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  877 EEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLhgtvMKINQERAEELQE 956
Cdd:TIGR00618  697 EMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKAR----TEAHFNNNEEVTA 772

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 2462622367  957 AERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFR 993
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIG 809
46 PHA02562
endonuclease subunit; Provisional
 278-515 1.77e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.01  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  278 DLEKKMIEtEELKSkQTRFLEEIKNQDKLNKSLKEEAMLQ-KQSCEELKSDLNTKNELYAEIDKaPDESPyiGKSRYKRN 356
Cdd:PHA02562   187 DMKIDHIQ-QQIKT-YNKNIEEQRKKNGENIARKQNKYDElVEEAKTIKAEIEELTDELLNLVM-DIEDP--SAALNKLN 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  357 MFATESyiidSAQAVQIKKMEpdeqlrndHMNLRGHT-PLDTQ-LEDKEKKISAAQTRLSELHDEIEKAEQQIlraTEEF 434
Cdd:PHA02562   262 TAAAKI----KSKIEQFQKVI--------KMYEKGGVcPTCTQqISEGPDRITKIKDKLKELQHSLEKLDTAI---DELE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  435 KQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHshmKAQKSGKEQQLDIMNKQYQQLESRLD 514
Cdd:PHA02562   327 EIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDN---AEELAKLQDELDKIVKTKSELVKEKY 403


                   .
gi 2462622367  515 E 515
Cdd:PHA02562   404 H 404
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 271-644 1.80e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  271 EVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAmlqkqscEELKSDLNTKNELYAEIDKAPDESPYigk 350
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARI-------EELEEDLHKLEEALNDLEARLSHSRI--- 793

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  351 srykrnmfatesyiidsaQAVQIKKMEPDEQLRNdhmnlrghtpLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRA 430
Cdd:TIGR02169  794 ------------------PEIQAELSKLEEEVSR----------IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  431 TEEFKQLEEAIQlkkealDLELQMEKQKQEIAGKQKEIKDLqiaIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLE 510
Cdd:TIGR02169  846 KEQIKSIEKEIE------NLNGKKEELEEELEELEAALRDL---ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  511 SRLDEILSRIAKETEEIKDLEEQLTEGQ-IAANEALKKDLEGVISGLQE---YLGTIKGQATQAQNECRKLRDEKETLLQ 586
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEeIPEEELSLEDVQAELQRVEEeirALEPVNMLAIQEYEEVLKRLDELKEKRA 996

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  587 RLTEveqERDQLEIVAMDAENMRKelaelESALQEQHEVNASLQQTQGDLSAYEAELE 644
Cdd:TIGR02169  997 KLEE---ERKAILERIEEYEKKKR-----EVFMEAFEAINENFNEIFAELSGGTGELI 1046
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1758-1961 1.88e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1758 NLEKLELNVRKLQQELDQLNRdklslhndISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLhtTKHQDVLLSEQT 1837
Cdd:COG4913    236 DLERAHEALEDAREQIELLEP--------IRELAERYAAARERLAELEYLRAALRLWFAQRRLELL--EAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1838 RLQKDISEWANRFEDCQKE-EETKQQ-------QLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQ 1909
Cdd:COG4913    306 RLEAELERLEARLDALREElDELEAQirgnggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462622367 1910 QHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERwceSLEKTLSQTKRQ 1961
Cdd:COG4913    386 RAEAAALLEALEEELEALEEALAEAEAALRDLRRELR---ELEAEIASLERR 434
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1256-1526 1.95e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.04  E-value: 1.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKREERWMR-------ASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDF 1328
Cdd:PRK02224   211 LESELAELDEEIERYEEQREQARETRdeadevlEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1329 IDGNVESLMTELEIEKSlkHHEDIVDEIEciekTLLKRRSELREAdrlLAEAESELSCTKEKTKNAVEKFTDAKRSLLQT 1408
Cdd:PRK02224   291 LEEERDDLLAEAGLDDA--DAEAVEARRE----ELEDRDEELRDR---LEECRVAAQAHNEEAESLREDADDLEERAEEL 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1409 ESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKD 1488
Cdd:PRK02224   362 REEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARER 441

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462622367 1489 IEMAER--------------NEDHHLQVLKESEVLLQAKRAELEKLKSQVTS 1526
Cdd:PRK02224   442 VEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEE 493
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1407-1604 2.15e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1407 QTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQ 1486
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1487 KDIE-----MAERNEDHHLQVLKESEVLLQAKRAeLEKLKSQVTSQQQEMAVLDRQLghkkEELHLLQGSMVQAKADLQE 1561
Cdd:COG4942    104 EELAellraLYRLGRQPPLALLLSPEDFLDAVRR-LQYLKYLAPARREQAEELRADL----AELAALRAELEAERAELEA 178

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462622367 1562 ALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQ 1604
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1694-2141 2.69e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 2.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1694 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQsnlekLELNVRKLQQEL 1773
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEA-----LEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1774 DQLNRDklslhndisamQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQdvllseqtrlqkdISEWANRFEDC 1853
Cdd:COG4717    149 EELEER-----------LEELRELEEELEELEAELAELQEELEELLEQLSLATEEE-------------LQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1854 QKEEETKQQQLQVLQNEIE--ENKLKLVQQEMMFQRLQKERESEESKLE-TSKVTLKEQQHQLEKELTDQKSKLDQVLSK 1930
Cdd:COG4717    205 QQRLAELEEELEEAQEELEelEEELEQLENELEAAALEERLKEARLLLLiAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1931 VLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQlveksgELLALQKEADSMRADFSLLRNQFLTERKKAEKQVAS 2010
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELE------ELLAALGLPPDLSPEELLELLDRIEELQELLREAEE 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2011 LKEALKIQRSQLEKNLLM--ANQKDLE--RRQMEISDAMRTLKSEVKdEIRTSLKNLNQFLPELPA--DLEAILERNENL 2084
Cdd:COG4717    359 LEEELQLEELEQEIAALLaeAGVEDEEelRAALEQAEEYQELKEELE-ELEEQLEELLGELEELLEalDEEELEEELEEL 437

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367 2085 EGELESLKENLPFTMNE-GPFEEKLnfsqvhimdEHWRGEALREKLRHREDRLKAQLR 2141
Cdd:COG4717    438 EEELEELEEELEELREElAELEAEL---------EQLEEDGELAELLQELEELKAELR 486
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 148-179 3.05e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 43.00  E-value: 3.05e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462622367  148 KLRELNLSYNKISKIEGIENMCNLQKLNLAGN 179
Cdd:pfam12799    2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGN 33
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1858-2056 3.17e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1858 ETKQQQLQVLQ------NEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVT-LKEQQHQLEKELTDQKSKLDQVLSK 1930
Cdd:COG4913    245 EDAREQIELLEpirelaERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEeLRAELARLEAELERLEARLDALREE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1931 VLAAEERVRTLQEEERwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQ-------FLTERKK 2003
Cdd:COG4913    325 LDELEAQIRGNGGDRL--EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEaaalleaLEEELEA 402

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462622367 2004 AEKQVASLKEALKIQRSQLEKnlLMANQKDLERRQMEISDAMRTLKSEVKDEI 2056
Cdd:COG4913    403 LEEALAEAEAALRDLRRELRE--LEAEIASLERRKSNIPARLLALRDALAEAL 453
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1799-2004 3.75e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1799 EAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKL 1878
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1879 VQQE-----------------------------------MMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSK 1923
Cdd:COG4942    100 EAQKeelaellralyrlgrqpplalllspedfldavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1924 LDQvlskvlaaeervrtlQEEERwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKK 2003
Cdd:COG4942    180 LAE---------------LEEER--AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   .
gi 2462622367 2004 A 2004
Cdd:COG4942    243 T 243
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1728-2137 3.89e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 3.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1728 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAvnslQEE 1807
Cdd:PLN02939    49 KRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKD----GEQ 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1808 LANVQdhlnlaKQDLLHTTKH--QDVLLSEQTRLQKdisewANRFEDCQKEEETKQQQLQVLQNEIEEN--KLKLVQQEM 1883
Cdd:PLN02939   125 LSDFQ------LEDLVGMIQNaeKNILLLNQARLQA-----LEDLEKILTEKEALQGKINILEMRLSETdaRIKLAAQEK 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1884 M-FQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSK----------LDQVLSKVLAAEERVRTLQEEERWCES-- 1950
Cdd:PLN02939   194 IhVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEEnmllkddiqfLKAELIEVAETEERVFKLEKERSLLDAsl 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1951 --LEKTLSQTKR---QLSEREQQ-LVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEAlKIQRSQLEK 2024
Cdd:PLN02939   274 reLESKFIVAQEdvsKLSPLQYDcWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEA-NVSKFSSYK 352

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2025 NLLMANQKDLERRQMEISDAmrtlksevkdEIRTSLKNLNQFLPELPADLEAILErnenlegelESLKENLPFTMNEGPF 2104
Cdd:PLN02939   353 VELLQQKLKLLEERLQASDH----------EIHSYIQLYQESIKEFQDTLSKLKE---------ESKKRSLEHPADDMPS 413

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 2462622367 2105 EeklNFSQVHIMDEHWRGEA---------LREKLRHREDRLK 2137
Cdd:PLN02939   414 E---FWSRILLLIDGWLLEKkisnndaklLREMVWKRDGRIR 452
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1354-1564 4.13e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1354 DEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQL 1433
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1434 RSLQADAKDL--EQHKIKQEEILKEINKIVAAKDS--DFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVL 1509
Cdd:COG4942    100 EAQKEELAELlrALYRLGRQPPLALLLSPEDFLDAvrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1510 LQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQgsmvQAKADLQEALR 1564
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ----QEAEELEALIA 230
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
437-659 4.16e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.86  E-value: 4.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  437 LEEAIQLKKEALD-----LELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDpkhshmkaQKSGKEQQLDIMNKQYQQLES 511
Cdd:COG3206    162 LEQNLELRREEARkalefLEEQLPELRKELEEAEAALEEFRQKNGLVDLSE--------EAKLLLQQLSELESQLAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  512 RLDEILSRIAKETEEIKDLEEQLTE-GQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNecrkLRDEKETLLQRL-T 589
Cdd:COG3206    234 ELAEAEARLAALRAQLGSGPDALPElLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIA----LRAQIAALRAQLqQ 309

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  590 EVEQERDQLEIvamDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKE 659
Cdd:COG3206    310 EAQRILASLEA---ELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
DUF4175 pfam13779
Domain of unknown function (DUF4175);
396-660 4.87e-05

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 48.83  E-value: 4.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  396 DTQLEDKEKKISAAQTRLSEL------HDEIEKAEQQILRATEEF-KQLEEaiQLKKEALDLELQMEKQKQEIAGK--QK 466
Cdd:pfam13779  481 DGDLSDAERRLRAAQERLSEAlergasDEEIAKLMQELREALDDYmQALAE--QAQQNPQDLQQPDDPNAQEMTQQdlQR 558

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  467 EIKDLQIAIDSLDSKDPKH---------SHMKAQKSGKEQQlDIMNKQYQQLESrldeiLSRIAKETEEIKDleEQLTEG 537
Cdd:pfam13779  559 MLDRIEELARSGRRAEAQQmlsqlqqmlENLQAGQPQQQQQ-QGQSEMQQAMDE-----LGDLLREQQQLLD--ETFRQL 630

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  538 QIAANEALKKDLEGVISGLQEYLGTIKGQ------ATQAQNECRKLRDEKETLLQRLTEVEQerdqlEIVAMDAENMRKE 611
Cdd:pfam13779  631 QQQGGQQQGQPGQQGQQGQGQQPGQGGQQpgaqmpPQGGAEALGDLAERQQALRRRLEELQD-----ELKELGGKEPGQA 705

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462622367  612 LAElesALQEQHEVNASLQQTQGDlSAYEAELEARLNLRD---AEANQLKEE 660
Cdd:pfam13779  706 LGD---AGRAMRDAEEALGQGDLA-GAVDAQGRALEALRKgaqQLAEAMQQQ 753
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1889-2093 4.87e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1889 QKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLS---KVLAAEERVRTLQEEERwceSLEKTLSQTKRQLSER 1965
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAlerRIAALARRIRALEQELA---ALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1966 EQQLVEKSGEL------------------LALQKEADSMRADFSLLRnQFLTERKKAEKQVASLKEALKIQRSQLEknll 2027
Cdd:COG4942     96 RAELEAQKEELaellralyrlgrqpplalLLSPEDFLDAVRRLQYLK-YLAPARREQAEELRADLAELAALRAELE---- 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 2028 mANQKDLERRQMEISDAMRTLKSEvKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKE 2093
Cdd:COG4942    171 -AERAELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
PRK11281 PRK11281
mechanosensitive channel MscK;
1692-1946 6.01e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 48.37  E-value: 6.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1692 QKQLLERDKREIErmTAESRALQSCVEclskEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLE-------- 1763
Cdd:PRK11281    42 QAQLDALNKQKLL--EAEDKLVQQDLE----QTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKddndeetr 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1764 -----LNVRKLQQELDQLNRDKLSLHND---------------------ISAMQQQLQEKREAVNSLQEElanvQDHLNL 1817
Cdd:PRK11281   116 etlstLSLRQLESRLAQTLDQLQNAQNDlaeynsqlvslqtqperaqaaLYANSQRLQQIRNLLKGGKVG----GKALRP 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1818 AKQDLLHTtkhQDVLLSEQTRLQKDISEWANRFEDC---QKEEETK-----QQQLQVLQNEIEENKLKLVQQEMMfqrlQ 1889
Cdd:PRK11281   192 SQRVLLQA---EQALLNAQNDLQRKSLEGNTQLQDLlqkQRDYLTAriqrlEHQLQLLQEAINSKRLTLSEKTVQ----E 264

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462622367 1890 KERESEESKLETSKVTLKEQQ--HQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEER 1946
Cdd:PRK11281   265 AQSQDEAARIQANPLVAQELEinLQLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSER 323
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1354-2089 6.46e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 6.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1354 DEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQL 1433
Cdd:pfam01576   12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1434 RSLQADAKDLEQHKIKQEEILKEinkivaaKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAK 1513
Cdd:pfam01576   92 QQLQNEKKKMQQHIQDLEEQLDE-------EEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1514 RAEL----EKLKS-QVTSQQQEMAVLDRQLGHKKEElhllqgsmvQAKADLQEALRLGETEVTEKCNHIREVKSLLEELS 1588
Cdd:pfam01576  165 TSNLaeeeEKAKSlSKLKNKHEAMISDLEERLKKEE---------KGRQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1589 FQkgelNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNildmlQLENHELQGLKLQHDQR--VSELEKTQV 1666
Cdd:pfam01576  236 AQ----LAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQE-----DLESERAARNKAEKQRRdlGEELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1667 AVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQscveclSKEKEDLQEkcdiwekKLAQTKRVLA 1746
Cdd:pfam01576  307 ELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKH------TQALEELTE-------QLEQAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1747 AAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLlhtt 1826
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLL---- 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1827 khqDVLLSEQTRLQKDISEWANRFEDCQK--EEETKQQ---QLQVLQNEIEENKLklvqqemmfqrlqKERESEEsklET 1901
Cdd:pfam01576  450 ---NEAEGKNIKLSKDVSSLESQLQDTQEllQEETRQKlnlSTRLRQLEDERNSL-------------QEQLEEE---EE 510

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1902 SKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQ-----------EEERWCESLEKTLSQTKRQLSE------ 1964
Cdd:pfam01576  511 AKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQrelealtqqleEKAAAYDKLEKTKNRLQQELDDllvdld 590

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1965 REQQLVEKsgeLLALQKEADSMRADFSLLRNQFLTERKKAEKQvASLKEALKIQRSQLEKNLLMAnQKDLERRQMEISDA 2044
Cdd:pfam01576  591 HQRQLVSN---LEKKQKKFDQMLAEEKAISARYAEERDRAEAE-AREKETRALSLARALEEALEA-KEELERTNKQLRAE 665

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 2462622367 2045 MRTLKSEvKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELE 2089
Cdd:pfam01576  666 MEDLVSS-KDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQ 709
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1256-1808 7.30e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 7.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1256 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVES 1335
Cdd:PRK01156   164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1336 LMTELEIEKslKHHEDIvdeiecieKTLLKRRSELREADRLLAEAESELsctKEKTKNAVEKFTDAKRSLLQTESDAEEL 1415
Cdd:PRK01156   244 LSSLEDMKN--RYESEI--------KTAESDLSMELEKNNYYKELEERH---MKIINDPVYKNRNYINDYFKYKNDIENK 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1416 ERRAQETAVNLVKAD---QQLRSLQADAKDLEQHKIKQEEILKEINKIvAAKDSDFQCLSKKKEKLTEELQKLQKDIEMA 1492
Cdd:PRK01156   311 KQILSNIDAEINKYHaiiKKLSVLQKDYNDYIKKKSRYDDLNNQILEL-EGYEMDYNSYLKSIESLKKKIEEYSKNIERM 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1493 ERNEDHHLQVLKESEVLLQAKRAE----LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKAdlqeALRLGET 1568
Cdd:PRK01156   390 SAFISEILKIQEIDPDAIKKELNEinvkLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVC----GTTLGEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1569 EVTEKCNHIREVKSLLEE-LSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDML-QLENHE 1646
Cdd:PRK01156   466 KSNHIINHYNEKKSRLEEkIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKInELKDKH 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1647 LQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQIS----QQQKGEIEWQKQLLERDKREIE---------------RMT 1707
Cdd:PRK01156   546 DKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDietnRSRSNEIKKQLNDLESRLQEIEigfpddksyidksirEIE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1708 AESRALQSCVECLSKEK---EDLQEKCDIWEKKLAQTKRVlaaaEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLH 1784
Cdd:PRK01156   626 NEANNLNNKYNEIQENKiliEKLRGKIDNYKKQIAEIDSI----IPDLKEITSRINDIEDNLKKSRKALDDAKANRARLE 701

                          570       580
                   ....*....|....*....|....
gi 2462622367 1785 NDISAMQQQLQEKREAVNSLQEEL 1808
Cdd:PRK01156   702 STIEILRTRINELSDRINDINETL 725
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
507-694 8.06e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 8.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  507 QQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKK----DLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKE 582
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  583 TLLQRLTEVEQERDQL----EIVAMDAE--NMRKELAELESALQEQHEvnaslqqtqgDLSAYEAELEARLNLRDAEANQ 656
Cdd:COG3206    244 ALRAQLGSGPDALPELlqspVIQQLRAQlaELEAELAELSARYTPNHP----------DVIALRAQIAALRAQLQQEAQR 313

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462622367  657 LKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 694
Cdd:COG3206    314 ILASLEAELEALQAREASLQAQLAQLEARLAELPELEA 351
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 376-708 8.89e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.02  E-value: 8.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  376 MEPDEQLRNDHMNLRgHTPLDTQ---------LEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKE 446
Cdd:COG3096    325 LEQDYQAASDHLNLV-QTALRQQekieryqedLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQ 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  447 ALD------LELQMEKQKQEIAGKQKEIKDLqiaidSLDSKDPKHSHMKAQKS-------GKEQQLDIMNKQYQQLESRL 513
Cdd:COG3096    404 ALDvqqtraIQYQQAVQALEKARALCGLPDL-----TPENAEDYLAAFRAKEQqateevlELEQKLSVADAARRQFEKAY 478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  514 dEILSRIAKETEEikdleeqlTEGQIAANEALK-----KDLEGVISGLQEYLGTIKgQATQAQNECRKLRDEketLLQRL 588
Cdd:COG3096    479 -ELVCKIAGEVER--------SQAWQTARELLRryrsqQALAQRLQQLRAQLAELE-QRLRQQQNAERLLEE---FCQRI 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  589 TEVEQERDQLEIVAMDAEnmrKELAELESALQEQHEVNASLQQTQGDLSAYEAELEAR----LNLRDAeANQLKEEL-EK 663
Cdd:COG3096    546 GQQLDAAEELEELLAELE---AQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapawLAAQDA-LERLREQSgEA 621

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 2462622367  664 VTRLTQLeQSALQAELEKERQALKNALGKAQFSEEKEQENSELHA 708
Cdd:COG3096    622 LADSQEV-TAAMQQLLEREREATVERDELAARKQALESQIERLSQ 665
PRK11281 PRK11281
mechanosensitive channel MscK;
400-724 9.72e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 9.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  400 EDKEKKISAAQTRlsELHDEIEKAEQQILRATEEFkqLEEAIQLKKEALDLelqmekqKQEIAGKQKEIKDLQIAIDSLd 479
Cdd:PRK11281    39 ADVQAQLDALNKQ--KLLEAEDKLVQQDLEQTLAL--LDKIDRQKEETEQL-------KQQLAQAPAKLRQAQAELEAL- 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  480 skdpkhshmkaqksgKEQQLDIMNKQYqqlesrldeilsriakETEEIKDLEEQLTEGQIAANEAlkkdlegvisglQEY 559
Cdd:PRK11281   107 ---------------KDDNDEETRETL----------------STLSLRQLESRLAQTLDQLQNA------------QND 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  560 LGTIKGQATQAQNecrklrdeketllqrltevEQERDQleiVAMDAENMRkeLAELESALQEQHEVNASLQQTQGDLsay 639
Cdd:PRK11281   144 LAEYNSQLVSLQT-------------------QPERAQ---AALYANSQR--LQQIRNLLKGGKVGGKALRPSQRVL--- 196

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  640 eaeLEARLNLRDAEANQLKEELEKVTRLTQLEQS------ALQAELEKERQALKNALG--KAQFSEE--KEQENSELHAK 709
Cdd:PRK11281   197 ---LQAEQALLNAQNDLQRKSLEGNTQLQDLLQKqrdyltARIQRLEHQLQLLQEAINskRLTLSEKtvQEAQSQDEAAR 273

                          330
                   ....*....|....*
gi 2462622367  710 LKHlqddNNLLKQQL 724
Cdd:PRK11281   274 IQA----NPLVAQEL 284
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 507-664 1.01e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.07  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  507 QQLESRLDEILSRIAKETEEIKDLEEQLT--EGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKE-- 582
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAalEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEye 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  583 TLLQRLTEVEQERDQLEivamdaENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELE 662
Cdd:COG1579     93 ALQKEIESLKRRISDLE------DEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166


                   ..
gi 2462622367  663 KV 664
Cdd:COG1579    167 EL 168
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1757-2042 1.04e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.77  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1757 SNLEKLELNVRKLQQELDQLNRDKLSLhnDISAMQQQLQEKREAVNSLQEELANVQDHlnlaKQDLLHTTKHQDVLLSEQ 1836
Cdd:COG5022    787 VDYELKWRLFIKLQPLLSLLGSRKEYR--SYLACIIKLQKTIKREKKLRETEEVEFSL----KAEVLIQKFGRSLKAKKR 860

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1837 TRLQKDisewANRFEDCQKEEETKQQQLQVLQNEIEE-NKLKLVQQEMMFQRLQKERESEESKLETSKVTLKE----QQH 1911
Cdd:COG5022    861 FSLLKK----ETIYLQSAQRVELAERQLQELKIDVKSiSSLKLVNLELESEIIELKKSLSSDLIENLEFKTELiarlKKL 936

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1912 QLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 1991
Cdd:COG5022    937 LNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTK 1016

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462622367 1992 LL--RNQFLTERKKAEKQVASLKEALKIQRSQLE-KNLLMANQKDLERRQMEIS 2042
Cdd:COG5022   1017 QLkeLPVEVAELQSASKIISSESTELSILKPLQKlKGLLLLENNQLQARYKALK 1070
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1653-1873 1.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1653 QHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCD 1732
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1733 IWEKKLAQTKRVLAAAEENSKME----QSNLEKLELNVRKLQqeldQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEEL 1808
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLK----YLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1809 ANVQDHLNLAKQDLLHTTKHQDVLLseqTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEE 1873
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1359-1990 1.32e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1359 IEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQA 1438
Cdd:TIGR00618  188 KKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1439 DAKDLE----------------QHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKL------------QKDIE 1490
Cdd:TIGR00618  268 RIEELRaqeavleetqerinraRKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRaahvkqqssieeQRRLL 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1491 MAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEV 1570
Cdd:TIGR00618  348 QTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1571 TEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ--EIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQ 1648
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSlkEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLC 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1649 GLKL---QHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE 1725
Cdd:TIGR00618  508 GSCIhpnPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1726 DLQEkcdiwekklaQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLnrdklslhnDISAMQQQLQEKREavnslQ 1805
Cdd:TIGR00618  588 NLQN----------ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQ---------DVRLHLQQCSQELA-----L 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1806 EELANVQDHLNLAKQDLLH---TTKHQDVLLSEQTRLQKDISEWANRFEDCQKEE-ETKQQQLQVLQNEIEENKLKLVQQ 1881
Cdd:TIGR00618  644 KLTALHALQLTLTQERVREhalSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMlAQCQTLLRELETHIEEYDREFNEI 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1882 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT-DQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKR 1960
Cdd:TIGR00618  724 ENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTeAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKT 803

                          650       660       670
                   ....*....|....*....|....*....|
gi 2462622367 1961 QLSEREQQLVEKSGELLALQKEADSMRADF 1990
Cdd:TIGR00618  804 LEAEIGQEIPSDEDILNLQCETLVQEEEQF 833
PRK12704 PRK12704
phosphodiesterase; Provisional
 402-541 1.34e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  402 KEKKISAAQtrlSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQ-MEKQKQEIAGKQKEIKDlqiaidslds 480
Cdd:PRK12704    55 KKEALLEAK---EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLElLEKREEELEKKEKELEQ---------- 121

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367  481 kdpkhshmkaqksgKEQQLDIMNKQYQQLESRLDEILSRIAKETEE------IKDLEEQLTEgQIAA 541
Cdd:PRK12704   122 --------------KQQELEKKEEELEELIEEQLQELERISGLTAEeakeilLEKVEEEARH-EAAV 173
LRR_8 pfam13855
Leucine rich repeat;
170-220 1.68e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.36  E-value: 1.68e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462622367  170 NLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSL--QDISKLKPLQDL 220
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLspGAFSGLPSLRYL 54
46 PHA02562
endonuclease subunit; Provisional
 399-602 1.98e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.55  E-value: 1.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  399 LEDKEKKISAAQTRLSELHDE----IEKAEQQILRATEEFKQLEEAIQLKKEAL-DLELQMEKQKQEIAGKQKEIKDLQ- 472
Cdd:PHA02562   204 IEEQRKKNGENIARKQNKYDElveeAKTIKAEIEELTDELLNLVMDIEDPSAALnKLNTAAAKIKSKIEQFQKVIKMYEk 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  473 -----IAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQltEGQIAANEALKK 547
Cdd:PHA02562   284 ggvcpTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTN--KQSLITLVDKAK 361

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367  548 DLEGVISGLQEYLGTIKGqatqaqnECRKLRDEKETLLQRLTEVEQERDQLEIVA 602
Cdd:PHA02562   362 KVKAAIEELQAEFVDNAE-------ELAKLQDELDKIVKTKSELVKEKYHRGIVT 409
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1461-1710 2.00e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1461 VAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGH 1540
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1541 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTlikqeiekeeeNLQ 1620
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-----------ELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1621 VVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQvavleekleLENLQQISQQQKGEIEWQKQL--LER 1698
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKEL---------AELAAELAELQQEAEELEALIarLEA 234

                          250
                   ....*....|..
gi 2462622367 1699 DKREIERMTAES 1710
Cdd:COG4942    235 EAAAAAERTPAA 246
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 395-893 2.22e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAI--------QLKKEALDLELQMEKQKQEIAGKQK 466
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELeklnnkynDLKKQKEELENELNLLEKEKLNIQK 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  467 EIKD-------LQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEE------------- 526
Cdd:TIGR04523  188 NIDKiknkllkLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQlnqlkdeqnkikk 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  527 ---------------IKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEV 591
Cdd:TIGR04523  268 qlsekqkeleqnnkkIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQL 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  592 EQERDQLEivaMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKvtrltqLE 671
Cdd:TIGR04523  348 KKELTNSE---SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKK------LQ 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  672 QSALQAELEKERQALKNALGKAQFSEEKEQeNSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLvrpeevaarvDEL 751
Cdd:TIGR04523  419 QEKELLEKEIERLKETIIKNNSEIKDLTNQ-DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNL----------EQK 487

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  752 RRKLKLGTGEMnihspsdvlgKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFrqaceraLEA 831
Cdd:TIGR04523  488 QKELKSKEKEL----------KKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDEL-------NKD 550

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462622367  832 RMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKK 893
Cdd:TIGR04523  551 DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKI 612
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 76-205 2.34e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 45.94  E-value: 2.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   76 SHAGVRYITEALikkltkQDNLALiKSLNLSLSKDGGKKFKYI-ENLEKCVKLEVLNLSYNLIGK------IEKLDKLLK 148
Cdd:COG5238    277 GAEGAIALAKAL------QGNTTL-TSLDLSVNRIGDEGAIALaEGLQGNKTLHTLNLAYNGIGAqgaialAKALQENTT 349

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367  149 LRELNLSYNKISK------IEGIENMCNLQKLNLAGNEI-EHIPVWLGKKLK--SLRVLNLKGNKI 205
Cdd:COG5238    350 LHSLDLSDNQIGDegaialAKYLEGNTTLRELNLGKNNIgKQGAEALIDALQtnRLHTLILDGNLI 415
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 1697-1927 2.41e-04

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 45.57  E-value: 2.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1697 ERDKReIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRV--LAAAEENSKMEQSNLEKLELNVRKLQQELD 1774
Cdd:pfam15905   91 EQDKR-LQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELTRVneLLKAKFSEDGTQKKMSSLSMELMKLRNKLE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1775 QLNRDKLSLHNDisaMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQ 1854
Cdd:pfam15905  170 AKMKEVMAKQEG---MEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIA 246

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462622367 1855 KEEET---KQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKvtlKEQQHQLEKELTDQKSKLDQV 1927
Cdd:pfam15905  247 QLEELlkeKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREY---EEKEQTLNAELEELKEKLTLE 319
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1471-1983 2.43e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 46.25  E-value: 2.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1471 LSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQG 1550
Cdd:pfam05483  217 LKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1551 SMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHK 1630
Cdd:pfam05483  297 ELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1631 TELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQ---ISQQQKGEIEWQKQLLERDKREIERMT 1707
Cdd:pfam05483  377 DQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQfekIAEELKGKEQELIFLLQAREKEIHDLE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1708 AESRALQSCVECLSKEKEDLqeKCDIWEKKLAQTKRVlaaaeenskmeqSNLEKLELNVRKLQQELDQLNRDKLSLHNDI 1787
Cdd:pfam05483  457 IQLTAIKTSEEHYLKEVEDL--KTELEKEKLKNIELT------------AHCDKLLLENKELTQEASDMTLELKKHQEDI 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1788 SAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLH-----------TTKHQDVLLSEQTRLQKDISEWANRFEDCQKE 1856
Cdd:pfam05483  523 INCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQkgdevkckldkSEENARSIEYEVLKKEKQMKILENKCNNLKKQ 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1857 EETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV----L 1932
Cdd:pfam05483  603 IENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVekakA 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1933 AAEERVRTLQEEERWCE-------------------------------------------SLEKTLSQTKRQLSEREQQL 1969
Cdd:pfam05483  683 IADEAVKLQKEIDKRCQhkiaemvalmekhkhqydkiieerdselglyknkeqeqssakaALEIELSNIKAELLSLKKQL 762

                          570
                   ....*....|....
gi 2462622367 1970 VEKSGELLALQKEA 1983
Cdd:pfam05483  763 EIEKEEKEKLKMEA 776
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 488-692 2.45e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.07  E-value: 2.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  488 MKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLtegqiaanEALK--KDLEGVISGLQ--EYLGTI 563
Cdd:PRK05771    77 KKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEI--------ERLEpwGNFDLDLSLLLgfKYVSVF 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  564 KGQATQAQNECRKLRDEKETLLqrltEVEQERDQLEIVAM----DAENMRKELAELEsaLQEQHEvnaslqQTQGDLSAY 639
Cdd:PRK05771   149 VGTVPEDKLEELKLESDVENVE----YISTDKGYVYVVVVvlkeLSDEVEEELKKLG--FERLEL------EEEGTPSEL 216

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367  640 EAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAEL--EKERQALKNALGK 692
Cdd:PRK05771   217 IREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLeiELERAEALSKFLK 271
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1759-1917 2.70e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.92  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1759 LEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS--EQ 1836
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEY 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1837 TRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKE 1916
Cdd:COG1579     92 EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171


                   .
gi 2462622367 1917 L 1917
Cdd:COG1579    172 I 172
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1284-1536 3.19e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1284 KRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESlmteleiekslkhhEDIVDEIECIEKTL 1363
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEA--------------KLLLQQLSELESQL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1364 LKRRSELREADRLLAEAESELSCTKEKTKNAVEK--FTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQAdak 1441
Cdd:COG3206    229 AEARAELAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRA--- 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1442 dleqhkikqeEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEV---LLQAKRAELE 1518
Cdd:COG3206    306 ----------QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVareLYESLLQRLE 375

                          250
                   ....*....|....*...
gi 2462622367 1519 KLKSQVTSQQQEMAVLDR 1536
Cdd:COG3206    376 EARLAEALTVGNVRVIDP 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1577-1803 3.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1577 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQ 1656
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1657 RVSELEKTQVAVLEEKLELENLQQISQQQKGEI----EWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKcd 1732
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL-- 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462622367 1733 iwEKKLAQTKRVLAAAEENskmEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS 1803
Cdd:COG4942    180 --LAELEEERAALEALKAE---RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 76-181 3.56e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 45.04  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   76 SHAGVRYITEALikklTKQDNLALIKSLNLSLSKDGGKKFKyiENLEKCVKLEVLNLSYNLIGK--IEKLDKLLK----- 148
Cdd:cd00116    178 GDAGIRALAEGL----KANCNLEVLDLNNNGLTDEGASALA--ETLASLKSLEVLNLGDNNLTDagAAALASALLspnis 251

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 2462622367  149 LRELNLSYNKI------SKIEGIENMCNLQKLNLAGNEI 181
Cdd:cd00116    252 LLTLSLSCNDItddgakDLAEVLAEKESLLELDLRGNKF 290
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 486-1490 3.82e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 3.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  486 SHMKAQKSGKEQQLDIMNKQYQQLESRLDEI------LSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEy 559
Cdd:TIGR02168  168 SKYKERRKETERKLERTRENLDRLEDILNELerqlksLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQE- 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  560 lgtikgQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAE----NMRKELAELESALQEQHEVNASLQQTQGD 635
Cdd:TIGR02168  247 ------ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelyALANEISRLEQQKQILRERLANLERQLEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  636 LSAYEAELEARLNLRDAEANQLKEELEKVTRLTQlEQSALQAELEKERQALKNALGKAQfsEEKEQENSELHAKLKHLQD 715
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEELE--EQLETLRSKVAQLELQIAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  716 DNNLLkQQLKDFQNHLNHvvdglvRPEEVAARVDELRRKLklgtgemnihspsdvlgkSLADLQKQfSEILARSKWERDE 795
Cdd:TIGR02168  398 LNNEI-ERLEARLERLED------RRERLQQEIEELLKKL------------------EEAELKEL-QAELEELEEELEE 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  796 AQVRERKLQEEMALQQEKLATGQEEFRQAceRALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDL--QLQ 873
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAA--ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELI 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  874 EADEEKER-ILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKInqerAE 952
Cdd:TIGR02168  530 SVDEGYEAaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV----AK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  953 ELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEK----------TGVGTGANSQVL----EIEKLNET 1018
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggviTGGSAKTNSSILerrrEIEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1019 MERQRTEIARLQNVLDltgsDNKGGFENVLEEIAELRREVSYQNDYISSMADPFKRRgywyfmpPPPSSKVSSHSSQATK 1098
Cdd:TIGR02168  686 IEELEEKIAELEKALA----ELRKELEELEEELEQLRKELEELSRQISALRKDLARL-------EAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1099 DSGVGLKYSAStpvrkprpgqqdgkegsqpppasgywvyspIRSGLHKLFPSRDADSGGDSQEESELDDQEEppfvpppg 1178
Cdd:TIGR02168  755 ELTELEAEIEE------------------------------LEERLEEAEEELAEAEAEIEELEAQIEQLKE-------- 796

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1179 ymmytvlpdgspvpqgmalyapppPLPNNSRPLTpgtvvygpppagapmvygppppnfsipfipmgvlhcnvpehhNLEN 1258
Cdd:TIGR02168  797 ------------------------ELKALREALD------------------------------------------ELRA 810

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1259 EVSRLEDIMQHLKSKKREERWMRASKrqsEKEMEELHHNIDDLLQEKKSLECEVEELhrTVQKRQQQKDFIDGNVESLMT 1338
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAAT---ERRLEDLEEQIEELSEDIESLAAEIEEL--EELIEELESELEALLNERASL 885

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1339 ELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELsctkEKTKNAVEKFTDAKRSLLQTEsdAEELERR 1418
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL----EGLEVRIDNLQERLSEEYSLT--LEEAEAL 959

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462622367 1419 AQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKivaakdsDFQCLSKKKEKLTEELQKLQKDIE 1490
Cdd:TIGR02168  960 ENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKE-------RYDFLTAQKEDLTEAKETLEEAIE 1024
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 496-902 4.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 4.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  496 EQQLDIMNKQYQQLESRLDE--ILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGV-----ISGLQEYLGTIKgQAT 568
Cdd:COG3096    285 ERALELRRELFGARRQLAEEqyRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALrqqekIERYQEDLEELT-ERL 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  569 QAQNECRKLRDEKETLLQ-RLTEVEQERDQLeivamdaenmRKELAELESALQEQHEVNASLQQTQGDLSAYEAELE-AR 646
Cdd:COG3096    364 EEQEEVVEEAAEQLAEAEaRLEAAEEEVDSL----------KSQLADYQQALDVQQTRAIQYQQAVQALEKARALCGlPD 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  647 LNLRDAEANQ--LKEELEKVT-RLTQLEQ-----SALQAELEKERQALKNALGKAQFSE--EKEQENSELHAKLKHLQDD 716
Cdd:COG3096    434 LTPENAEDYLaaFRAKEQQATeEVLELEQklsvaDAARRQFEKAYELVCKIAGEVERSQawQTARELLRRYRSQQALAQR 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  717 NNLLKQQLKdfqnhlnhvvdglvrpeevaarvdELRRKLklgtgemnihspsdvlgKSLADLQKQFSEILARSKWERDEA 796
Cdd:COG3096    514 LQQLRAQLA------------------------ELEQRL-----------------RQQQNAERLLEEFCQRIGQQLDAA 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  797 QVRERKLQEemalQQEKLATGQEEFRQACERALEARMNFDkrQHEARIQQMEN---EIHYLQENLKSMEEIQGLTDLQLQ 873
Cdd:COG3096    553 EELEELLAE----LEAQLEELEEQAAEAVEQRSELRQQLE--QLRARIKELAArapAWLAAQDALERLREQSGEALADSQ 626

                          410       420
                   ....*....|....*....|....*....
gi 2462622367  874 EADEEKERILAQLRELEKKKKLEDAKSQE 902
Cdd:COG3096    627 EVTAAMQQLLEREREATVERDELAARKQA 655
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1842-2024 5.40e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 5.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1842 DISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQK 1921
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1922 ------SKLDQVL---------------SKVLAAEERVRTLQEEERwcESLEKTLSQTKRQLSEREQQLveksGELLALQ 1980
Cdd:COG3883     97 rsggsvSYLDVLLgsesfsdfldrlsalSKIADADADLLEELKADK--AELEAKKAELEAKLAELEALK----AELEAAK 170

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462622367 1981 KEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEK 2024
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
504-1058 6.09e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 6.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  504 KQYQQLESRLDEILSRIAKETEEIKDLEEQLTEgqiaaneaLKKDLEGVISGLQEyLGTIKGQATQAQNECRKLRDEKET 583
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSELPE--------LREELEKLEKEVKE-LEELKEEIEELEKELESLEGSKRK 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  584 LLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEK 663
Cdd:PRK03918   257 LEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEK 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  664 VTRLTQLEQsaLQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNnlLKQQLKDFQNHLNHVVDGLVRPEE 743
Cdd:PRK03918   337 EERLEELKK--KLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEK--LEKELEELEKAKEEIEEEISKITA 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  744 VAARVDELRRKLKLGTGEM-NIHSPSDVLGKSL-----ADLQKQFSEILARSKWERDEAQVRERKLQE-----EMALQQE 812
Cdd:PRK03918   413 RIGELKKEIKELKKAIEELkKAKGKCPVCGRELteehrKELLEEYTAELKRIEKELKEIEEKERKLRKelrelEKVLKKE 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  813 KLATGQEEFRQACERALEARMNFDKRQHEARIQQMENeihyLQENLKSME-EIQGLTD--LQLQEADEEKERILAQLREL 889
Cdd:PRK03918   493 SELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEK----LKEKLIKLKgEIKSLKKelEKLEELKKKLAELEKKLDEL 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  890 EKKKKLEDAKSQEQVFGLDKELKKLKKAVAT------SDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRK 963
Cdd:PRK03918   569 EEELAELLKELEELGFESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  964 AAQAARDLTRAEAEiELLQNLLRQKGEQFRLEMEKtgvgTGANSQVLEIEKLNETMERQRTEIARLQNVLDLtgsdnkgg 1043
Cdd:PRK03918   649 LEELEKKYSEEEYE-ELREEYLELSRELAGLRAEL----EELEKRREEIKKTLEKLKEELEEREKAKKELEK-------- 715

                          570
                   ....*....|....*
gi 2462622367 1044 FENVLEEIAELRREV 1058
Cdd:PRK03918   716 LEKALERVEELREKV 730
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1247-1888 6.60e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 6.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1247 HCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECE---VEELHRTVQKRQ 1323
Cdd:TIGR00618  279 LEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQrrlLQTLHSQEIHIR 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1324 QQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKR 1403
Cdd:TIGR00618  359 DAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQR 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1404 SLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKiVAAKDSDFQCLSKKKEK------ 1477
Cdd:TIGR00618  439 YAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLA-RLLELQEEPCPLCGSCIhpnpar 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1478 -LTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAK 1556
Cdd:TIGR00618  518 qDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQ 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1557 ADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTEL--- 1633
Cdd:TIGR00618  598 DLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELlas 677

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1634 -KNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESra 1712
Cdd:TIGR00618  678 rQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV-- 755

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1713 lqscveclSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNdisAMQQ 1792
Cdd:TIGR00618  756 --------LKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILN---LQCE 824

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1793 QLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQkdisewanrfedcqkEEETKQQQLQVLQNEIE 1872
Cdd:TIGR00618  825 TLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKII---------------QLSDKLNGINQIKIQFD 889

                          650
                   ....*....|....*.
gi 2462622367 1873 ENKLKLVQQEMMFQRL 1888
Cdd:TIGR00618  890 GDALIKFLHEITLYAN 905
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1270-2075 8.55e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 8.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1270 LKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLEceveelhrtvqkrqqqkdfidgnvESLMTELEiekslkhh 1349
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQ------------------------EQLQAETE-------- 54

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1350 edIVDEIECIEKTLLKRRSELREadrLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA 1429
Cdd:pfam01576   55 --LCAEAEEMRARLAARKQELEE---ILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTT 129

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1430 DQQLRSLQADAKDLEQhkikQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE-MAERNEDHHLQVLKESEV 1508
Cdd:pfam01576  130 EAKIKKLEEDILLLED----QNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEaMISDLEERLKKEEKGRQE 205

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1509 LLQAKR---AELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQ---AKADLQEALRLGETEVTEKCNHIREVKS 1582
Cdd:pfam01576  206 LEKAKRkleGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEetaQKNNALKKIRELEAQISELQEDLESERA 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1583 LLEELSFQKGELNVQISERKTQLtlikqEIEKEEENLQVVLRqmSKHKTELKNILDMLQLE--NHE--LQGLKLQHDQRV 1658
Cdd:pfam01576  286 ARNKAEKQRRDLGEELEALKTEL-----EDTLDTTAAQQELR--SKREQEVTELKKALEEEtrSHEaqLQEMRQKHTQAL 358

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1659 SELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIE----RMTAESRALQSCVECLSKEKEDLQEKCDIW 1734
Cdd:pfam01576  359 EELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEhkrkKLEGQLQELQARLSESERQRAELAEKLSKL 438

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLS-------LHNDISAMQQQLQEKREAVNSLQEE 1807
Cdd:pfam01576  439 QSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNlstrlrqLEDERNSLQEQLEEEEEAKRNVERQ 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1808 LANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQR 1887
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSN 598

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1888 LQKER------------------------ESEESKLETSKVTL-------KEQQHQLEKELTDQKSKLDQVLSKVLAAEE 1936
Cdd:pfam01576  599 LEKKQkkfdqmlaeekaisaryaeerdraEAEAREKETRALSLaraleeaLEAKEELERTNKQLRAEMEDLVSSKDDVGK 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1937 RVRTLQEEERwceSLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSL---LRNQFLTERKKA-EKQVASLK 2012
Cdd:pfam01576  679 NVHELERSKR---ALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERdlqARDEQGEEKRRQlVKQVRELE 755

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 2013 EALKIQRSQleKNLLMANQKDLErrqMEISDAMRTLKSEVK--DEIRTSLKNLNQFLPELPADLE 2075
Cdd:pfam01576  756 AELEDERKQ--RAQAVAAKKKLE---LDLKELEAQIDAANKgrEEAVKQLKKLQAQMKDLQRELE 815
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1652-1961 8.62e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.73  E-value: 8.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1652 LQHDQRVSELEKTQvavLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESrALQSCVECLSKEKEDLQEKC 1731
Cdd:pfam17380  278 VQHQKAVSERQQQE---KFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQA-AIYAEQERMAMERERELERI 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1732 DIWEKKLAQTK-RVLAAAEENSKMEQsnLEKLELNVR----KLQQELDQLNRDKLSLHNDISAMQQQLQEKrEAVNSLQE 1806
Cdd:pfam17380  354 RQEERKRELERiRQEEIAMEISRMRE--LERLQMERQqkneRVRQELEAARKVKILEEERQRKIQQQKVEM-EQIRAEQE 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1807 ELANVQ-DHLNLAKQDLLHTTKHQDVLLSEQT-RLQKDISEWANRFEDCQKEEETKQ----QQLQVLQNEIEENKLKLVQ 1880
Cdd:pfam17380  431 EARQREvRRLEEERAREMERVRLEEQERQQQVeRLRQQEEERKRKKLELEKEKRDRKraeeQRRKILEKELEERKQAMIE 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1881 QEMMFQRLQKERESEESKL-ETSKVTLKEQQHQLEKELTDQKSKLDQVLskvLAAEERVRtLQEEERWCESLEKTLSQTK 1959
Cdd:pfam17380  511 EERKRKLLEKEMEERQKAIyEEERRREAEEERRKQQEMEERRRIQEQMR---KATEERSR-LEAMEREREMMRQIVESEK 586


                   ..
gi 2462622367 1960 RQ 1961
Cdd:pfam17380  587 AR 588
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1422-1607 8.99e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 8.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1422 TAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQ 1501
Cdd:COG3883      7 AAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1502 VLKES--------------EVLLQAK-------RAE-LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADL 1559
Cdd:COG3883     87 ELGERaralyrsggsvsylDVLLGSEsfsdfldRLSaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAEL 166

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462622367 1560 QEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTL 1607
Cdd:COG3883    167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1693-2016 9.26e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 9.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1693 KQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTkrvlaaaeenskMEQSNLEKLELNVRKLQQE 1772
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS------------WDEIDVASAEREIAELEAE 676

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1773 LDQLNRDklslHNDISAMQQQLQEKREAVNSLQEELAnvqdhlnlakqdllhttkhqdvllseqtRLQKDISEWANRFED 1852
Cdd:COG4913    677 LERLDAS----SDDLAALEEQLEELEAELEELEEELD----------------------------ELKGEIGRLEKELEQ 724

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1853 CQKEEETKQQQLQVLQNEIEENKLKLVqQEMMFQRLQKERESEESK-LETSKVTLKEQQHQLEKELTDQKSKLDQV-LSK 1930
Cdd:COG4913    725 AEEELDELQDRLEAAEDLARLELRALL-EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREwPAE 803

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1931 VLAAEERVRTLQEEERWCESLEktlsqtkrqlserEQQLVEKSGELLALQKEAdsMRADFSLLRNQFLTERKKAEKQVAS 2010
Cdd:COG4913    804 TADLDADLESLPEYLALLDRLE-------------EDGLPEYEERFKELLNEN--SIEFVADLLSKLRRAIREIKERIDP 868


                   ....*.
gi 2462622367 2011 LKEALK 2016
Cdd:COG4913    869 LNDSLK 874
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 395-830 1.03e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.43  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  395 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEE-AIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQI 473
Cdd:pfam10174  294 LKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQrAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTE 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  474 AIDSLDSKdpkHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQL--TEGQIAANEALKKDLEG 551
Cdd:pfam10174  374 EKSTLAGE---IRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSsnTDTALTTLEEALSEKER 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  552 VISGLQEylgtikgqatQAQNECRklrdeketllQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQ 631
Cdd:pfam10174  451 IIERLKE----------QREREDR----------ERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLAS 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  632 TQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQ-----AELEKERQALKNALGKAQFSEE------KE 700
Cdd:pfam10174  511 SGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEindriRLLEQEVARYKEESGKAQAEVErllgilRE 590

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  701 QENsELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGlvRPEEVAARVDELRRKLKLGTGEMNIHSpsdvlgksladlQK 780
Cdd:pfam10174  591 VEN-EKNDKDKKIAELESLTLRQMKEQNKKVANIKHG--QQEMKKKGAQLLEEARRREDNLADNSQ------------QL 655

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462622367  781 QFSEILA---RSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALE 830
Cdd:pfam10174  656 QLEELMGaleKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILE 708
46 PHA02562
endonuclease subunit; Provisional
 453-699 1.03e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  453 QMEK-QKQEIAGKQKEIKDLQIAIDSLDSKdpkhshMKAQKSGKEQQldimNKQYQQLESRLDEILSRIAKETEEIKDLE 531
Cdd:PHA02562   167 EMDKlNKDKIRELNQQIQTLDMKIDHIQQQ------IKTYNKNIEEQ----RKKNGENIARKQNKYDELVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  532 EQLTEgQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKE--TLLQ-------RLTEVEQERDQLEIVA 602
Cdd:PHA02562   237 EELTD-ELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVcpTCTQqisegpdRITKIKDKLKELQHSL 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  603 MDAENMRKELAELESALQEQ----HEVNASLQQTQGDLSAYeaelearlnlrDAEANQLKEELEKVTRLTQLEQSALqAE 678
Cdd:PHA02562   316 EKLDTAIDELEEIMDEFNEQskklLELKNKISTNKQSLITL-----------VDKAKKVKAAIEELQAEFVDNAEEL-AK 383

                          250       260
                   ....*....|....*....|.
gi 2462622367  679 LEKERQALKNAlgKAQFSEEK 699
Cdd:PHA02562   384 LQDELDKIVKT--KSELVKEK 402
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1709-1937 1.14e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1709 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLnRDKLSlhNDIS 1788
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEER-REELG--ERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1789 AMQQQlqekrEAVNSLQEELANVQDHlnlakQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQ 1868
Cdd:COG3883     94 ALYRS-----GGSVSYLDVLLGSESF-----SDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462622367 1869 NEIEENKLKLvqqemmfQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEER 1937
Cdd:COG3883    164 AELEAAKAEL-------EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1753-2076 1.14e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 44.27  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1753 KMEQSNLEKLELNVRKLQQ-----------ELDQLNRDKLSLHNDISAMQ----QQLQEKREAVNSLQEELANVQDHLNL 1817
Cdd:PTZ00108   995 KRKEYLLGKLERELARLSNkvrfikhvingELVITNAKKKDLVKELKKLGyvrfKDIIKKKSEKITAEEEEGAEEDDEAD 1074

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1818 AKQDLLHT--TKHQDVLLSEQ-TRLQKDisewanRFEDCQKEEETKQQQLQVLQN-EIEE------NKLKLVQQEMMFQR 1887
Cdd:PTZ00108  1075 DEDDEEELgaAVSYDYLLSMPiWSLTKE------KVEKLNAELEKKEKELEKLKNtTPKDmwledlDKFEEALEEQEEVE 1148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1888 LQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERwceSLEKTLSQTKRQLSEREQ 1967
Cdd:PTZ00108  1149 EKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKR---KLDDKPDNKKSNSSGSDQ 1225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1968 QLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLMANQKDLERRQMEISDAMRT 2047
Cdd:PTZ00108  1226 EDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSP 1305

                          330       340
                   ....*....|....*....|....*....
gi 2462622367 2048 LKSEVKDEIRTSLKNLNQFLPELPADLEA 2076
Cdd:PTZ00108  1306 TKKKVKKRLEGSLAALKKKKKSEKKTARK 1334
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1740-2031 1.16e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1740 QTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAK 1819
Cdd:COG4372     21 KTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQ 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1820 QDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKL 1899
Cdd:COG4372    101 EELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1900 ETSKVTLKEQQHQLEKELTDQKSKLDQ---VLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL 1976
Cdd:COG4372    181 AEQALDELLKEANRNAEKEEELAEAEKlieSLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEI 260

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367 1977 LALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLMANQ 2031
Cdd:COG4372    261 EELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALED 315
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1653-2101 1.20e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1653 QHDQRVseLEKTQVAVLEEKLELENLQQISQQQKGeieWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCD 1732
Cdd:pfam15921   74 EHIERV--LEEYSHQVKDLQRRLNESNELHEKQKF---YLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQ 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1733 IWEKKLAQTKRVLAAAEENSKMEQSNLEKLELN-------VRKLQQELDQLNRDKLSLHNDIS---------AMQQQLQE 1796
Cdd:pfam15921  149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLShegvlqeIRSILVDFEEASGKKIYEHDSMStmhfrslgsAISKILRE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1797 KREAVNSLQEELANVQDHLNLAKQDllHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKL 1876
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSE--SQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1877 KLVQQEMMFQRLQKERESEESKLET----SKVTLKEQQHQLEKELTDQKSKLDQvlskvlAAEERVRTLQEEERWCESLE 1952
Cdd:pfam15921  307 QARNQNSMYMRQLSDLESTVSQLRSelreAKRMYEDKIEELEKQLVLANSELTE------ARTERDQFSQESGNLDDQLQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1953 KTLSQTKRQlsEREQQLVEKSGELLALQKEADSMRADFslLRNQfLTERKKAEKQVASLKEALKIQ-RSQLEKNL--LMA 2029
Cdd:pfam15921  381 KLLADLHKR--EKELSLEKEQNKRLWDRDTGNSITIDH--LRRE-LDDRNMEVQRLEALLKAMKSEcQGQMERQMaaIQG 455

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367 2030 NQKDLER-----RQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNE 2101
Cdd:pfam15921  456 KNESLEKvssltAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQE 532
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1396-2172 1.23e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1396 EKFTDAKRSLLQTESDAEELERRAQETAVNLVK-ADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAK---DSDFQCL 1471
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERlRREREKAERYQALLKEKREYEGYELLKEKEALERQKeaiERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1472 SKKKEKLTEELQKLQKDIEMAERN-EDHHLQVLKESEVLLQAKRAELEKLKSQVTSqqqemavLDRQLGHKKEELHllqg 1550
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLlEELNKKIKDLGEEEQLRVKEKIGELEAEIAS-------LERSIAEKERELE---- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1551 smvqakaDLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHK 1630
Cdd:TIGR02169  319 -------DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1631 TEL---KNILDMLQLENHELQGLKLQHDQRVSELEktqvavleeklelenlqqisQQQKGEIEWQKQLLERDKREIERMT 1707
Cdd:TIGR02169  392 EKLeklKREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIK 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1708 AESRALQSCVECLSKEKE---DLQEKCDIWEKKLAQTKRVLAAAEEnskmEQSNLEKLELNVRKLQQELDQLNRDKLSLH 1784
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQelyDLKEEYDRVEKELSKLQRELAEAEA----QARASEERVRGGRAVEEVLKASIQGVHGTV 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1785 NDISAMQQQLQEKRE--AVNSLQ----EELANVQDHLNLAKQ------DLLHTTKHQDVLLSEQTRLQKDISEWANRFED 1852
Cdd:TIGR02169  528 AQLGSVGERYATAIEvaAGNRLNnvvvEDDAVAKEAIELLKRrkagraTFLPLNKMRDERRDLSILSEDGVIGFAVDLVE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1853 CQKEEETKQQQL---QVLQNEIEENKLKLVQQEMM----------------------FQRLQKERESEESKLETSKVTLK 1907
Cdd:TIGR02169  608 FDPKYEPAFKYVfgdTLVVEDIEAARRLMGKYRMVtlegelfeksgamtggsraprgGILFSRSEPAELQRLRERLEGLK 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1908 EQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEErwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMR 1987
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI---EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1988 ADFSLLrnqflterkkaEKQVASLKEALKiqrsqleknllmanqkDLERR-QMEISDAMRTLKSEVKDEIRTSLKNLNqf 2066
Cdd:TIGR02169  765 ARIEEL-----------EEDLHKLEEALN----------------DLEARlSHSRIPEIQAELSKLEEEVSRIEARLR-- 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2067 lpelpaDLEAILERNENLEGELESLKENLpftmnegpfEEKLNFSQVHIMDEHWRGEALREKLRHREDRLKaqlrhcmSK 2146
Cdd:TIGR02169  816 ------EIEQKLNRLTLEKEYLEKEIQEL---------QEQRIDLKEQIKSIEKEIENLNGKKEELEEELE-------EL 873

                          810       820
                   ....*....|....*....|....*.
gi 2462622367 2147 QAEVlikgkRQTEGTLHSLRRQVDAL 2172
Cdd:TIGR02169  874 EAAL-----RDLESRLGDLKKERDEL 894
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1287-1601 1.24e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1287 SEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDfiDGNVESLMTELE-------IEKSLKHHEDIVDEIECI 1359
Cdd:PRK02224   410 AEDFLEELREERDELREREAELEATLRTARERVEEAEALLE--AGKCPECGQPVEgsphvetIEEDRERVEELEAELEDL 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1360 EKTLLKRRSELREADRLlAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAvnlVKADQQlrslQAD 1439
Cdd:PRK02224   488 EEEVEEVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELE---AEAEEK----REA 559

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1440 AKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSK------KKEKLTEELQKLQ-KDIEMAERNEDH--HLQVLKESEVLL 1510
Cdd:PRK02224   560 AAEAEEEAEEAREEVAELNSKLAELKERIESLERirtllaAIADAEDEIERLReKREALAELNDERreRLAEKRERKREL 639

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1511 QAK--RAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS--MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE 1586
Cdd:PRK02224   640 EAEfdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigAVENELEELEELRERREALENRVEALEALYDEAEE 719

                          330
                   ....*....|....*
gi 2462622367 1587 LSFQKGELNVQISER 1601
Cdd:PRK02224   720 LESMYGDLRAELRQR 734
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1363-2067 1.27e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1363 LLKRRSELREADRLLAEAESELSCTK-EKTKNAVE----KFTDAKRSLLQTESDAE--ELERRAQETAVNLVKADQQL-- 1433
Cdd:pfam12128  155 LGRERVELRSLARQFALCDSESPLRHiDKIAKAMHskegKFRDVKSMIVAILEDDGvvPPKSRLNRQQVEHWIRDIQAia 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1434 ---------RSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDhhlqv 1502
Cdd:pfam12128  235 gimkirpefTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKekRDELNGE----- 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1503 LKESEVLLQAKRAELEKLKSQVTSQQQEmavldrqlGHKKEELHLLQGSMVQAKADLQEALRLGETE----VTEKCNHIR 1578
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLDA--------DIETAAADQEQLPSWQSELENLEERLKALTGkhqdVTAKYNRRR 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1579 EVKS--LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQvvlRQMSKHKTELKNILDMLQLENHELQG------- 1649
Cdd:pfam12128  382 SKIKeqNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELR---EQLEAGKLEFNEEEYRLKSRLGELKLrlnqata 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1650 ---LKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQ--------SCVE 1718
Cdd:pfam12128  459 tpeLLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELElqlfpqagTLLH 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1719 CLSKEKEDlqekcdiWEKKLAqtkRVLAAA-----------EENSKMEQSNLEKLELNVRKLQ-----QELDQLNRDKLS 1782
Cdd:pfam12128  539 FLRKEAPD-------WEQSIG---KVISPEllhrtdldpevWDGSVGGELNLYGVKLDLKRIDvpewaASEEELRERLDK 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1783 LHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEwanrfedcQKEEETKQQ 1862
Cdd:pfam12128  609 AEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNK--------ALAERKDSA 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1863 QLQVLQNEIEENKLKLVQQEMM-----------FQRLQKERESEESK----------LETSKVTLKEQQHQLEKELTDQK 1921
Cdd:pfam12128  681 NERLNSLEAQLKQLDKKHQAWLeeqkeqkrearTEKQAYWQVVEGALdaqlallkaaIAARRSGAKAELKALETWYKRDL 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1922 SKLDQVLSKVLAAEERVRTL-----------QEEERWCESLEKTLSQTKRQLSEreqQLVEKSGELLALQKEADSMRADF 1990
Cdd:pfam12128  761 ASLGVDPDVIAKLKREIRTLerkieriavrrQEVLRYFDWYQETWLQRRPRLAT---QLSNIERAISELQQQLARLIADT 837

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367 1991 SLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLMANQKDLERRQMEISDAMRTLkSEVKDEIRTSLKNLNQFL 2067
Cdd:pfam12128  838 KLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQL-EDLKLKRDYLSESVKKYV 913
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 413-882 1.30e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.01  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  413 LSELHDEIEKAEQQILRATEEFKQLEEAIQlkkealDLELQMEkqkQEIAGKQKeikdLQIAIDSLDSKDPKhshMKAQK 492
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKKKMQQHIQ------DLEEQLD---EEEAARQK----LQLEKVTTEAKIKK---LEEDI 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  493 SGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIK--------------DLEEQLT--EGQIAANEALKKDLEGVISGL 556
Cdd:pfam01576  141 LLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKslsklknkheamisDLEERLKkeEKGRQELEKAKRKLEGESTDL 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  557 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAE-LESALQEQHEVNASLQQTQGD 635
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEdLESERAARNKAEKQRRDLGEE 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  636 LSAYEAELEARLNL----------RDAEANQLKEELEKVTR--------LTQLEQSALQAELEKERQALKNALGKAQFSE 697
Cdd:pfam01576  301 LEALKTELEDTLDTtaaqqelrskREQEVTELKKALEEETRsheaqlqeMRQKHTQALEELTEQLEQAKRNKANLEKAKQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  698 EKEQENSELHAKLKHLQD-------DNNLLKQQLKDFQNHLNhvvDGLVRPEEVAARVDELRRKLKLGTGEMN-IHSPSD 769
Cdd:pfam01576  381 ALESENAELQAELRTLQQakqdsehKRKKLEGQLQELQARLS---ESERQRAELAEKLSKLQSELESVSSLLNeAEGKNI 457

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  770 VLGKSLADLQKQF---SEILARSKWERDEAQVRERKLQEEMALQQEKLATgQEEFRQACERALEArMNFDKRQHEARIQQ 846
Cdd:pfam01576  458 KLSKDVSSLESQLqdtQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEE-EEEAKRNVERQLST-LQAQLSDMKKKLEE 535

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 2462622367  847 MENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERI 882
Cdd:pfam01576  536 DAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKL 571
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1651-2070 1.37e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1651 KLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQscVECLS---KEKEDL 1727
Cdd:COG4913    266 AARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELE--AQIRGnggDRLEQL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1728 QEKCDIWEKKLAQTKRVLAAAEENSKM----EQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS 1803
Cdd:COG4913    344 EREIERLERELEERERRRARLEALLAAlglpLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1804 LQEELANVQ------------------DHLNLAKQDL-----------------------LHT--------TKHQDVLLS 1834
Cdd:COG4913    424 LEAEIASLErrksniparllalrdalaEALGLDEAELpfvgelievrpeeerwrgaiervLGGfaltllvpPEHYAAALR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1835 --EQTRLQK---------------------------------DISEWAN----RFED---CQKEEETKQ----------- 1861
Cdd:COG4913    504 wvNRLHLRGrlvyervrtglpdperprldpdslagkldfkphPFRAWLEaelgRRFDyvcVDSPEELRRhpraitragqv 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1862 --------------------------QQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLET---------SKVTL 1906
Cdd:COG4913    584 kgngtrhekddrrrirsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswDEIDV 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1907 KEQQHQLEkELTDQKSKLDQVLSKVLAAEERVRTLQEEErwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSM 1986
Cdd:COG4913    664 ASAEREIA-ELEAELERLDASSDDLAALEEQLEELEAEL---EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1987 RADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEknllmANQKDLERRQMEISDAMRTLKSE---VKDEIRTSLKNL 2063
Cdd:COG4913    740 EDLARLELRALLEERFAAALGDAVERELRENLEERID-----ALRARLNRAEEELERAMRAFNREwpaETADLDADLESL 814


                   ....*..
gi 2462622367 2064 NQFLPEL 2070
Cdd:COG4913    815 PEYLALL 821
PRK12704 PRK12704
phosphodiesterase; Provisional
 1428-1531 1.41e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1428 KADQQLRSLQADAKD-LEQHKIKQEEILKEinKIVAAKD------SDFQCLSKKKEKlteELQKLQKDIEMAERNEDHHL 1500
Cdd:PRK12704    28 IAEAKIKEAEEEAKRiLEEAKKEAEAIKKE--ALLEAKEeihklrNEFEKELRERRN---ELQKLEKRLLQKEENLDRKL 102

                           90       100       110
                   ....*....|....*....|....*....|.
gi 2462622367 1501 QVLKESEVLLQAKRAELEKLKSQVTSQQQEM 1531
Cdd:PRK12704   103 ELLEKREEELEKKEKELEQKQQELEKKEEEL 133
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1457-1916 1.50e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1457 INKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKEsevlLQAKRAELEKLKSQVTSQQQEMAVLDR 1536
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEE----LEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1537 QLGHKkeelhllqgSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEE 1616
Cdd:COG4717    124 LLQLL---------PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1617 ENLQVVLRQMSKHKTELKNILDMLQ---------LENHELQGLKLQHDQRVSELEKTQVAV----------LEEKLELEN 1677
Cdd:COG4717    195 QDLAEELEELQQRLAELEEELEEAQeeleeleeeLEQLENELEAAALEERLKEARLLLLIAaallallglgGSLLSLILT 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1678 LQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQS 1757
Cdd:COG4717    275 IAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR 354

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1758 NLEKL--ELNVRKLQQELDQL-NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQdvLLS 1834
Cdd:COG4717    355 EAEELeeELQLEELEQEIAALlAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEE 432

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1835 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLvQQEMMFQRLQkERESEESKLETSKVTLKEQQHQLE 1914
Cdd:COG4717    433 ELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ-ELEELKAELR-ELAEEWAALKLALELLEEAREEYR 510


                   ..
gi 2462622367 1915 KE 1916
Cdd:COG4717    511 EE 512
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1371-1925 1.59e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 1.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1371 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLE---QHK 1447
Cdd:pfam05483  229 EEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKmslQRS 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1448 IKQEEILKEinkivaakdsDFQCLSKKKEKLTEElqklqKDIEMAERNEDH--HLQVLKESEVLLQAKRAELEKLKSQVT 1525
Cdd:pfam05483  309 MSTQKALEE----------DLQIATKTICQLTEE-----KEAQMEELNKAKaaHSFVVTEFEATTCSLEELLRTEQQRLE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1526 SQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALR-LGETEVTEKCNhiREVKSLLEELSFQKGELNVQISERKTQ 1604
Cdd:pfam05483  374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKiLAEDEKLLDEK--KQFEKIAEELKGKEQELIFLLQAREKE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1605 LTLIKQEIEKEEENLQVVLRQMSKHKTELknildmlqlENHELQGLKLQHDQRVSELEK---TQVAVLEEKLELENLQQI 1681
Cdd:pfam05483  452 IHDLEIQLTAIKTSEEHYLKEVEDLKTEL---------EKEKLKNIELTAHCDKLLLENkelTQEASDMTLELKKHQEDI 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1682 SQQQKGEIEWQKQLLERDKREiermTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 1761
Cdd:pfam05483  523 INCKKQEERMLKQIENLEEKE----MNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNN 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1762 LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ----DHLNLAKQDLLHTTKHQDVLLSEQT 1837
Cdd:pfam05483  599 LKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKqkfeEIIDNYQKEIEDKKISEEKLLEEVE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1838 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLetsKVTLKEQQHQLEKEL 1917
Cdd:pfam05483  679 KAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSA---KAALEIELSNIKAEL 755


                   ....*...
gi 2462622367 1918 TDQKSKLD 1925
Cdd:pfam05483  756 LSLKKQLE 763
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1289-1863 1.69e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1289 KEMEELHHNIDDLLQEKKSLEcEVEELHRTVQKRQQQKDfidgnveslmtELEIEKSLKHHEDIVDEIECIEKTLLKRRS 1368
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE-PIRELAERYAAARERLA-----------ELEYLRAALRLWFAQRRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1369 ELREADRLLAEAESELsctkektKNAVEKFTDAKRSLLQTESDA-EELERRAQETAVNLVKADQQLRSLQADAKDLEQHK 1447
Cdd:COG4913    303 ELARLEAELERLEARL-------DALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLEALLAALGLPL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1448 IKQEEILKEINKIVAAKdsdfqclskkKEKLTEELQKLQKDIEMAERNEDHHLQVLKEsevlLQAKRAELEKLKSQVTSQ 1527
Cdd:COG4913    376 PASAEEFAALRAEAAAL----------LEALEEELEALEEALAEAEAALRDLRRELRE----LEAEIASLERRKSNIPAR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1528 QQEM-AVLDRQLGHKKEELHLLqGSMVQAKADLQE------------ALRLgetEVTEKcnHIREVKSLLEELsfqKGEL 1594
Cdd:COG4913    442 LLALrDALAEALGLDEAELPFV-GELIEVRPEEERwrgaiervlggfALTL---LVPPE--HYAAALRWVNRL---HLRG 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1595 NVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNIL----------DMLQLENHE----LQGL------KLQH 1654
Cdd:COG4913    513 RLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELgrrfdyvcvdSPEELRRHPraitRAGQvkgngtRHEK 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1655 DQRVSELEKTQVAVLEEKLELENLQQISQQQKgEIEWQKQLLERDKREIERMTAESRALQSCVEcLSKEKEDLQEkcdiW 1734
Cdd:COG4913    593 DDRRRIRSRYVLGFDNRAKLAALEAELAELEE-ELAEAEERLEALEAELDALQERREALQRLAE-YSWDEIDVAS----A 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1735 EKKLAQTKRVLAAAEENSkmeqSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDH 1814
Cdd:COG4913    667 EREIAELEAELERLDASS----DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL 742

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462622367 1815 LNLAKQDLLhTTKHQDVLLSEQTR-----LQKDISEWANRFEDCQKEEETKQQQ 1863
Cdd:COG4913    743 ARLELRALL-EERFAAALGDAVERelrenLEERIDALRARLNRAEEELERAMRA 795
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1332-1596 1.69e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.91  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1332 NVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEaesELSCTKEKTKNAVEKFTDAKRSLLqtesd 1411
Cdd:COG5022    798 KLQPLLSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAE---VLIQKFGRSLKAKKRFSLLKKETI----- 869

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1412 aeelerrAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDfqcLSKKKEKLTEELQKLQKDIEM 1491
Cdd:COG5022    870 -------YLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSD---LIENLEFKTELIARLKKLLNN 939

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1492 AERNEDHHLQVLKESEVL-LQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ---GSMVQAKADLQEALRLGE 1567
Cdd:COG5022    940 IDLEEGPSIEYVKLPELNkLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKkelAELSKQYGALQESTKQLK 1019

                          250       260       270
                   ....*....|....*....|....*....|..
gi 2462622367 1568 ---TEVTEKCNHIREVKSLLEELSFQKGELNV 1596
Cdd:COG5022   1020 elpVEVAELQSASKIISSESTELSILKPLQKL 1051
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1359-1519 1.71e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1359 IEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQ--ETAVNLVKADQQLRSL 1436
Cdd:COG1579     15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyEEQLGNVRNNKEYEAL 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1437 QADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAernedhhLQVLKESEVLLQAKRAE 1516
Cdd:COG1579     95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEE-------LAELEAELEELEAEREE 167


                   ...
gi 2462622367 1517 LEK 1519
Cdd:COG1579    168 LAA 170
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 170-213 1.74e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.00  E-value: 1.74e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2462622367  170 NLQKLNLAGNEIEHIPvwLGKKLKSLRVLNLKGN-KISSLQDISK 213
Cdd:pfam12799    2 NLEVLDLSNNQITDIP--PLAKLPNLETLDLSGNnKITDLSDLAN 44
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 524-732 1.74e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.50  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  524 TEEIKDLEEQLTEGQIAANEALkkdlEGVISGLQEYlgtiKGQATQAQnECRKLRDEKETLLQRL-TEVEQERDQLEIVA 602
Cdd:PRK10929    29 TQELEQAKAAKTPAQAEIVEAL----QSALNWLEER----KGSLERAK-QYQQVIDNFPKLSAELrQQLNNERDEPRSVP 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  603 --MDAENMRKELAELESAL--------QEQ---HEVNASLQQTQGDLSayeaelEARLNLRDAEaNQLKEELEKVTRLTQ 669
Cdd:PRK10929   100 pnMSTDALEQEILQVSSQLleksrqaqQEQdraREISDSLSQLPQQQT------EARRQLNEIE-RRLQTLGTPNTPLAQ 172

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367  670 LEQSALQAELEKeRQALKNALGKAQFSEEKEQENSELHAKLkhLQDDNNLLKQQLKDFQNHLN 732
Cdd:PRK10929   173 AQLTALQAESAA-LKALVDELELAQLSANNRQELARLRSEL--AKKRSQQLDAYLQALRNQLN 232
PLN03150 PLN03150
hypothetical protein; Provisional
 145-206 1.82e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.27  E-value: 1.82e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  145 KLLKLRELNLSYNKIskiEG-----IENMCNLQKLNLAGNEIE-HIPVWLGKkLKSLRVLNLKGNKIS 206
Cdd:PLN03150   440 KLRHLQSINLSGNSI---RGnippsLGSITSLEVLDLSYNSFNgSIPESLGQ-LTSLRILNLNGNSLS 503
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1252-1447 1.85e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1252 EHHNLENEVSRLEDIMQHLKSKKREERWmraskRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDG 1331
Cdd:COG4913    263 RYAAARERLAELEYLRAALRLWFAQRRL-----ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1332 NVEslmteleiekslkhhEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKftdAKRSLLQTESD 1411
Cdd:COG4913    338 DRL---------------EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE---AAALLEALEEE 399

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462622367 1412 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHK 1447
Cdd:COG4913    400 LEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1619-2039 2.07e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1619 LQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENlQQISQQQKGEIEWQKQLLER 1698
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEL-EALEAELAELPERLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1699 DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNR 1778
Cdd:COG4717    155 LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1779 DKLSLhndisAMQQQLQEKR---------------------------EAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV 1831
Cdd:COG4717    235 ELEAA-----ALEERLKEARlllliaaallallglggsllsliltiaGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1832 LLSEQTRLQKDISEWANRFEDCQKEEET-------KQQQLQVLQNEIE--ENKLKLVQQEMMFQRLQKERESEESKLETS 1902
Cdd:COG4717    310 LPALEELEEEELEELLAALGLPPDLSPEellelldRIEELQELLREAEelEEELQLEELEQEIAALLAEAGVEDEEELRA 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1903 KVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTlqeeerwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKE 1982
Cdd:COG4717    390 ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--------EELEEELEELEEELEELEEELEELREELAELEAE 461

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622367 1983 ADSMRADFSLLRNQFLTERKKAEKQvaslKEALKIQRSQLEKNLLMANQKDLERRQM 2039
Cdd:COG4717    462 LEQLEEDGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREERL 514
mukB PRK04863
chromosome partition protein MukB;
504-896 2.19e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  504 KQYQQLESRLDEILSRIAKETEEIKDLE------EQLTEGQIAAneALKKDLEGVISGLQEYLGTIKGQATQAQNECRKL 577
Cdd:PRK04863   786 KRIEQLRAEREELAERYATLSFDVQKLQrlhqafSRFIGSHLAV--AFEADPEAELRQLNRRRVELERALADHESQEQQQ 863

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  578 RDEKETLLQRLTEVEQERDQLEIvaMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEArlnLRDAEAN-- 655
Cdd:PRK04863   864 RSQLEQAKEGLSALNRLLPRLNL--LADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSV---LQSDPEQfe 938

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  656 QLKEELEKVTrlTQLEQSALQAELEKERQALKNALG--KAQFSEEKEQENSE-LHAKLKHLQDDNNLLKQQLKDFQNHL- 731
Cdd:PRK04863   939 QLKQDYQQAQ--QTQRDAKQQAFALTEVVQRRAHFSyeDAAEMLAKNSDLNEkLRQRLEQAEQERTRAREQLRQAQAQLa 1016

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  732 --NHVVDGLVRPEEVAAR-VDELRRKLKlgtgEMNIHSPSDVLGKSLADlQKQFSEILARSKWERDEAQVRERKLQEEMA 808
Cdd:PRK04863  1017 qyNQVLASLKSSYDAKRQmLQELKQELQ----DLGVPADSGAEERARAR-RDELHARLSANRSRRNQLEKQLTFCEAEMD 1091

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  809 LQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIH-----YLQ-ENLKSMEEIqGLTDLQLQEADEEKERi 882
Cdd:PRK04863  1092 NLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHrrelaYLSaDELRSMSDK-ALGALRLAVADNEHLR- 1169

                          410
                   ....*....|....
gi 2462622367  883 lAQLRELEKKKKLE 896
Cdd:PRK04863  1170 -DVLRLSEDPKRPE 1182
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1863-2027 2.21e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1863 QLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEqqhqLEKELTDQKSKLDQVLSKVLAAEER----- 1937
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELED----LEKEIKRLELEIEEVEARIKKYEEQlgnvr 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1938 ----VRTLQEEErwcESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 2013
Cdd:COG1579     87 nnkeYEALQKEI---ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163

                          170
                   ....*....|....
gi 2462622367 2014 ALKIQRSQLEKNLL 2027
Cdd:COG1579    164 EREELAAKIPPELL 177
mukB PRK04863
chromosome partition protein MukB;
1785-2095 2.27e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1785 NDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEdCQKEEETKQQQL 1864
Cdd:PRK04863   272 ADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLN-LVQTALRQQEKI 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1865 QVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKvtlkEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEE 1944
Cdd:PRK04863   351 ERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAE----EEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERA 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1945 ERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAdfslLRNQFL------------TERKKAEKQVASLK 2012
Cdd:PRK04863   427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQA----AHSQFEqayqlvrkiageVSRSEAWDVARELL 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2013 EALKIQRSQLEK-NLLMANQKDLERRQMEISDAMRTLKSEVKDEIRTslknlnqflPELPADLEAILERnenLEGELESL 2091
Cdd:PRK04863   503 RRLREQRHLAEQlQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKN---------LDDEDELEQLQEE---LEARLESL 570


                   ....
gi 2462622367 2092 KENL 2095
Cdd:PRK04863   571 SESV 574
PTZ00121 PTZ00121
MAEBL; Provisional
 1259-1516 2.29e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1259 EVSRLEDIMQHLKSKKREERWMRASKRQSE--KEMEELH--HNIDDLLQEKKSLECEVEELHRTVQKRQQQKdfidGNVE 1334
Cdd:PTZ00121  1520 EAKKADEAKKAEEAKKADEAKKAEEKKKADelKKAEELKkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE----ARIE 1595

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1335 SLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEE 1414
Cdd:PTZ00121  1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKK 1675

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1415 LERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQK-DIEMAE 1493
Cdd:PTZ00121  1676 KAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEaKKDEEE 1755

                          250       260
                   ....*....|....*....|...
gi 2462622367 1494 RNEDHHLQVLKESEVLLQAKRAE 1516
Cdd:PTZ00121  1756 KKKIAHLKKEEEKKAEEIRKEKE 1778
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1701-1951 2.53e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1701 REIERMTAESRALQSCVECLskekEDLQEKCDIWEKkLAQTKRVLAAAeenskMEQSNLEKLELNVRKLQQELDQLNRDK 1780
Cdd:COG4913    235 DDLERAHEALEDAREQIELL----EPIRELAERYAA-ARERLAELEYL-----RAALRLWFAQRRLELLEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1781 LSLHNDISAMQQQLQEKREAVNSLQEELANVQDhlnlakQDLlhttkhqdvllseqTRLQKDISEWANRFEDCQKEEETK 1860
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEAQIRGNGG------DRL--------------EQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1861 QQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRT 1940
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA 444

                          250
                   ....*....|.
gi 2462622367 1941 LQEEerWCESL 1951
Cdd:COG4913    445 LRDA--LAEAL 453
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 495-892 2.71e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  495 KEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQL---------TEGQIAANEALKKDLEGVISGLQEYLGTIKG 565
Cdd:pfam01576   10 KEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLqaetelcaeAEEMRARLAARKQELEEILHELESRLEEEEE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  566 QATQAQNECRKLRDEKETLLQRLTEVEQERD--QLEIVAMDAE-----------------------NMRKELAELESALQ 620
Cdd:pfam01576   90 RSQQLQNEKKKMQQHIQDLEEQLDEEEAARQklQLEKVTTEAKikkleedillledqnsklskerkLLEERISEFTSNLA 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  621 EQHEVNASLQQTQGDLSAYEAELEARLNlrdaEANQLKEELEKVTRLTQLEQSALQ---AELEKERQALKNALGKaqfse 697
Cdd:pfam01576  170 EEEEKAKSLSKLKNKHEAMISDLEERLK----KEEKGRQELEKAKRKLEGESTDLQeqiAELQAQIAELRAQLAK----- 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  698 eKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKL--KLGTGEMNIHSPSDVLGKSL 775
Cdd:pfam01576  241 -KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLgeELEALKTELEDTLDTTAAQQ 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  776 ADLQKQFSEILARSKWERDEAQVRERKLQEemalQQEKLATGQEEFRQACERALEARMNFDKRQheariQQMENEIHYLQ 855
Cdd:pfam01576  320 ELRSKREQEVTELKKALEEETRSHEAQLQE----MRQKHTQALEELTEQLEQAKRNKANLEKAK-----QALESENAELQ 390

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 2462622367  856 ENLKSMEEIQgltdlqlQEADEEKERILAQLRELEKK 892
Cdd:pfam01576  391 AELRTLQQAK-------QDSEHKRKKLEGQLQELQAR 420
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1387-1822 2.77e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1387 TKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQhKIKQEEILKEINKIVAAKDS 1466
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK-LLQLLPLYQELEALEAELAE 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1467 DFQCLSKKKEKLtEELQKLQKDIEMAERNEDHHLQVLKES-EVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEEL 1545
Cdd:COG4717    144 LPERLEELEERL-EELRELEEELEELEAELAELQEELEELlEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1546 HLLQGSMVQAKADLQealRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQ 1625
Cdd:COG4717    223 EELEEELEQLENELE---AAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1626 MSKHKTELKNILDMLQLENHELQGLKlqHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIer 1705
Cdd:COG4717    300 LGKEAEELQALPALEELEEEELEELL--AALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1706 mtaesralqsCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLE-LNVRKLQQELDQLNRDKLSLH 1784
Cdd:COG4717    376 ----------LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEaLDEEELEEELEELEEELEELE 445

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 2462622367 1785 NDISAMQQQLQEKREAVNSL--QEELANVQDHLNLAKQDL 1822
Cdd:COG4717    446 EELEELREELAELEAELEQLeeDGELAELLQELEELKAEL 485
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1786-1944 3.03e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1786 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQK--EEETKQQQ 1863
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1864 LQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLEtskvTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQE 1943
Cdd:COG1579     91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELA----ELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166


                   .
gi 2462622367 1944 E 1944
Cdd:COG1579    167 E 167
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 428-723 3.08e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 3.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  428 LRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDS-----------LDSKDPKHSHMKAQKSGKE 496
Cdd:pfam05483  202 LRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEkenkmkdltflLEESRDKANQLEEKTKLQD 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  497 QQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEE----------QLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQ 566
Cdd:pfam05483  282 ENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEdlqiatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSL 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  567 ATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEV---NASLQQTQGDLSAYEAEL 643
Cdd:pfam05483  362 EELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLldeKKQFEKIAEELKGKEQEL 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  644 EARLNLRDAEANQLKEELEKVTRLTQL---EQSALQAELEKERqaLKNALGKAQF------SEEKEQENSELHAKLKHLQ 714
Cdd:pfam05483  442 IFLLQAREKEIHDLEIQLTAIKTSEEHylkEVEDLKTELEKEK--LKNIELTAHCdkllleNKELTQEASDMTLELKKHQ 519


                   ....*....
gi 2462622367  715 DDNNLLKQQ 723
Cdd:pfam05483  520 EDIINCKKQ 528
PTZ00121 PTZ00121
MAEBL; Provisional
 1378-2079 3.80e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1378 AEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEI 1457
Cdd:PTZ00121  1060 AEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDA 1139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1458 NKIVAAK---DSDFQCLSKKKE--------------------------KLTEELQKLQ--KDIEMAERNEDhhLQVLKES 1506
Cdd:PTZ00121  1140 RKAEEARkaeDAKRVEIARKAEdarkaeearkaedakkaeaarkaeevRKAEELRKAEdaRKAEAARKAEE--ERKAEEA 1217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1507 EVLLQAKRAELEKLKSQVTSQQQEM----AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 1582
Cdd:PTZ00121  1218 RKAEDAKKAEAVKKAEEAKKDAEEAkkaeEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKK 1297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1583 LLE----ELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 1658
Cdd:PTZ00121  1298 AEEkkkaDEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1659 SELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQScvecLSKEKEDLQEKCDIWEKKL 1738
Cdd:PTZ00121  1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD----EAKKKAEEAKKADEAKKKA 1453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1739 AQTKRVLAA---AEENSKMEQSNLEKLElnvrklQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 1815
Cdd:PTZ00121  1454 EEAKKAEEAkkkAEEAKKADEAKKKAEE------AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA 1527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1816 NLA--KQDLLHTTKHQDVLLSEQTRLQKDI--SEWANRFEDCQKEEETKQQQLQVLQ--NEIEENKLKLVQ---QEMMFQ 1886
Cdd:PTZ00121  1528 KKAeeAKKADEAKKAEEKKKADELKKAEELkkAEEKKKAEEAKKAEEDKNMALRKAEeaKKAEEARIEEVMklyEEEKKM 1607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1887 RLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSERE 1966
Cdd:PTZ00121  1608 KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1967 QQLVEksgellALQKEADSMRaDFSLLRNQFLTERKKAEkQVASLKEALKIQRSQLEKNLLMANQKDLERRQMEisdamr 2046
Cdd:PTZ00121  1688 KKAAE------ALKKEAEEAK-KAEELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDE------ 1753

                          730       740       750
                   ....*....|....*....|....*....|...
gi 2462622367 2047 tlksEVKDEIRTSLKNLNQFLPELPADLEAILE 2079
Cdd:PTZ00121  1754 ----EEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
PRK12704 PRK12704
phosphodiesterase; Provisional
 1734-1896 3.85e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 3.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1734 WEKKLAQTKRVLAAAE-----ENSKMEQSNLEKL-ELNVR----KLQQELDQLNRDKLslhNDISAMQQQLQEKREAVNS 1803
Cdd:PRK12704    24 VRKKIAEAKIKEAEEEakrilEEAKKEAEAIKKEaLLEAKeeihKLRNEFEKELRERR---NELQKLEKRLLQKEENLDR 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1804 LQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEwanRFEDCQK--EEETKQQQLQVLQNEIEENKLKLVQQ 1881
Cdd:PRK12704   101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQ---ELERISGltAEEAKEILLEKVEEEARHEAAVLIKE 177

                          170
                   ....*....|....*
gi 2462622367 1882 EMMFQRLQKERESEE 1896
Cdd:PRK12704   178 IEEEAKEEADKKAKE 192
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1258-1662 4.09e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 4.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1258 NEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLEcEVEELHRTVQKRQQqkdfIDGNVESLM 1337
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE-KLLQLLPLYQELEA----LEAELAELP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1338 TELE-IEKSLKHHEDIVDEIECIEKTLLKRRSELREA-DRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEEL 1415
Cdd:COG4717    146 ERLEeLEERLEELRELEEELEELEAELAELQEELEELlEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1416 ERRAQETAVNLVKADQQLR---------------SLQADAKDLEQHKIKQEEILKEINKIVAAkdsDFQCLSKKKEKLTE 1480
Cdd:COG4717    226 EEELEQLENELEAAALEERlkearlllliaaallALLGLGGSLLSLILTIAGVLFLVLGLLAL---LFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1481 ELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQemavLDRQLGHKKEELhLLQGSMVQAKADLQ 1560
Cdd:COG4717    303 EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQE----LLREAEELEEEL-QLEELEQEIAALLA 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1561 EALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISER--------KTQLTLIKQEIEKEEENLQVVLRQMSKHKTE 1632
Cdd:COG4717    378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELeellealdEEELEEELEELEEELEELEEELEELREELAE 457

                          410       420       430
                   ....*....|....*....|....*....|
gi 2462622367 1633 LKNILDMLQlENHELQGLKLQHDQRVSELE 1662
Cdd:COG4717    458 LEAELEQLE-EDGELAELLQELEELKAELR 486
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 86-216 4.24e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.57  E-value: 4.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367   86 ALIKKLTKQDNLALIKSLNLSLSKDGGKKFkyIENLEKCV-KLEVLNLSYNLI--GKIEKLDKLL----KLRELNLSYNK 158
Cdd:cd00116     99 GVLESLLRSSSLQELKLNNNGLGDRGLRLL--AKGLKDLPpALEKLVLGRNRLegASCEALAKALranrDLKELNLANNG 176

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462622367  159 ISKiEGIENMC-------NLQKLNLAGNEIEHIPV----WLGKKLKSLRVLNLKGNKISSLqDISKLKP 216
Cdd:cd00116    177 IGD-AGIRALAeglkancNLEVLDLNNNGLTDEGAsalaETLASLKSLEVLNLGDNNLTDA-GAAALAS 243
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 400-732 4.33e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 41.98  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  400 EDKEKKISAAQTRLSELHdeiekaeqqilRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLD 479
Cdd:pfam05622   90 EELEKEVLELQHRNEELT-----------SLAEEAQALKDEMDILRESSDKVKKLEATVETYKKKLEDLGDLRRQVKLLE 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  480 SKDPKHSHMKAQ-------KSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLtegqiaanEALKKDLEGV 552
Cdd:pfam05622  159 ERNAEYMQRTLQleeelkkANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKL--------EALQKEKERL 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  553 IS---GLQEYLGTIK-GQATQAQnecrklrdeketLLQRLTEVEQERDQLEIVAmdAENMRKELAEleSALQEQHEVNAS 628
Cdd:pfam05622  231 IIerdTLRETNEELRcAQLQQAE------------LSQADALLSPSSDPGDNLA--AEIMPAEIRE--KLIRLQHENKML 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  629 LQQTQGDLSAYEAELEARLNlrdaEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHA 708
Cdd:pfam05622  295 RLGQEGSYRERLTELQQLLE----DANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLE 370

                          330       340
                   ....*....|....*....|....
gi 2462622367  709 KLKHLQDDNNLLKQQLKDFQNHLN 732
Cdd:pfam05622  371 KLHEAQSELQKKKEQIEELEPKQD 394
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1250-1602 4.83e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 4.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1250 VPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTV---------- 1319
Cdd:PRK03918   285 LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleerhely 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1320 --------QKRQQQKDFIDGNVESLMTELE-IEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSC---- 1386
Cdd:PRK03918   365 eeakakkeELERLKKRLTGLTPEKLEKELEeLEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVcgre 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1387 -TKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKiKQEEILKEINKIVAAKD 1465
Cdd:PRK03918   445 lTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKK 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1466 sdfqclSKKKEKLTEELQKLQKDIEMAERnEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD-RQLGHKKEE 1544
Cdd:PRK03918   524 ------AEEYEKLKEKLIKLKGEIKSLKK-ELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKE 596

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462622367 1545 LHLLQGSMVQAKA------DLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERK 1602
Cdd:PRK03918   597 LEPFYNEYLELKDaekeleREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE 660
PRK12705 PRK12705
hypothetical protein; Provisional
 568-703 4.98e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.00  E-value: 4.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  568 TQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAmDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARL 647
Cdd:PRK12705    40 QEAQKEAEEKLEAALLEAKELLLRERNQQRQEARR-EREELQREEERLVQKEEQLDARAEKLDNLENQLEEREKALSARE 118

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462622367  648 NLRDAEANQLKEELEKVTRLTQLEQ-----SALQAELEKERQALKNA-LGKAQFSEEKEQEN 703
Cdd:PRK12705   119 LELEELEKQLDNELYRVAGLTPEQArklllKLLDAELEEEKAQRVKKiEEEADLEAERKAQN 180
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 262-726 5.18e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 42.24  E-value: 5.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  262 EAFE--RFSLEEVERLERDLEKKMIETEELKSKQtrflEEIKNQDKLNKSLKEEAM------LQKQSC--EELKSdlntK 331
Cdd:pfam15818   11 EALEelRMRREAETQYEEQIGKIIVETQELKWQK----ETLQNQKETLAKQHKEAMavfkkqLQMKMCalEEEKG----K 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  332 NELYAEIdkapdespyigKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLrndHMNLRGHTPLDTQLEDKEKKISAAQT 411
Cdd:pfam15818   83 YQLATEI-----------KEKEIEGLKETLKALQVSKYSLQKKVSEMEQKL---QLHLLAKEDHHKQLNEIEKYYATITG 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  412 RLSELHDEIEKAEQQIlrateefkqlEEAIQLKKEALDLElqmEKQKQEIAGKQKEIKdlQIAIDSLDSKDPKHSHMKAQ 491
Cdd:pfam15818  149 QFGLVKENHGKLEQNV----------QEAIQLNKRLSALN---KKQESEICSLKKELK--KVTSDLIKSKVTCQYKMGEE 213

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  492 KSgkeqQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEE-------------QLTEGQIAANEALKKDLEgvisGLQE 558
Cdd:pfam15818  214 NI----NLTIKEQKFQELQERLNMELELNKKINEEITHIQEekqdiiisfqhmqQLLQQQTQANTEMEAELK----ALKE 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  559 ylgtiKGQATQAQNECR--KLRDEKETLLQRLTEVEQerdQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDL 636
Cdd:pfam15818  286 -----NNQTLERDNELQreKVKENEEKFLNLQNEHEK---ALGTWKKHVEELNGEINEIKNELSSLKETHIKLQEHYNKL 357

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  637 SAYEAELEARLNLRDAEANQLKEELEKvtrlTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDD 716
Cdd:pfam15818  358 CNQKKFEEDKKFQNVPEVNNENSEMST----EKSENLIIQKYNSEQEIREENTKSFCSDTEYRETEKKKGPPVEEIIIED 433

                          490
                   ....*....|
gi 2462622367  717 NNLLKQQLKD 726
Cdd:pfam15818  434 LQVLEKSFKN 443
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
391-622 5.30e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 41.98  E-value: 5.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  391 GHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAiQLKKEALDlELQMEKQKqeIAGKQKEIKD 470
Cdd:COG0497    152 GLEELLEEYREAYRAWRALKKELEELRADEAERARELDLLRFQLEELEAA-ALQPGEEE-ELEEERRR--LSNAEKLREA 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  471 LQIAIDSLDSKDPkhshmkaqksGKEQQLdimnkqyQQLESRLDeilsRIAKETEEIKDLEEQLTEGQIAANEALKkDLE 550
Cdd:COG0497    228 LQEALEALSGGEG----------GALDLL-------GQALRALE----RLAEYDPSLAELAERLESALIELEEAAS-ELR 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  551 GVISGL----------QEYLGTIKGQAtqaqnecRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQ 620
Cdd:COG0497    286 RYLDSLefdperleevEERLALLRRLA-------RKYGVTVEELLAYAEELRAELAELENSDERLEELEAELAEAEAELL 358


                   ..
gi 2462622367  621 EQ 622
Cdd:COG0497    359 EA 360
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 398-710 5.66e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.02  E-value: 5.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  398 QLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKEALDLELQMEKQKQEIAGK-----------QK 466
Cdd:pfam05483  371 RLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKeqelifllqarEK 450

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  467 EIKDLQIAIDSLDSKDPKHShmkaqKSGKEQQLDIMNKQYQQLE--SRLDEILSRIAKETEEIKDLEEQLTEGQIAANEA 544
Cdd:pfam05483  451 EIHDLEIQLTAIKTSEEHYL-----KEVEDLKTELEKEKLKNIEltAHCDKLLLENKELTQEASDMTLELKKHQEDIINC 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  545 LKKD---------LEGVISGLQEYLGTIKGQATQAQNECR-KLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAE 614
Cdd:pfam05483  526 KKQEermlkqienLEEKEMNLRDELESVREEFIQKGDEVKcKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN 605

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  615 LESALQEQHEVNASLQQTQGDLSayeaeleARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 694
Cdd:pfam05483  606 KNKNIEELHQENKALKKKGSAEN-------KQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVE 678

                          330
                   ....*....|....*.
gi 2462622367  695 FSEEKEQENSELHAKL 710
Cdd:pfam05483  679 KAKAIADEAVKLQKEI 694
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1893-2096 5.86e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 5.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1893 ESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEErwcESLEKTLSQTKRQLSEREQQLvek 1972
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEI---DKLQAEIAEAEAEIEERREEL--- 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1973 sGELLALQKEADSMRADFSLLRN-----QFLTERKKAEKQVASLKEALKIQRSQLEKnlLMANQKDLERRQMEISDAMRT 2047
Cdd:COG3883     89 -GERARALYRSGGSVSYLDVLLGsesfsDFLDRLSALSKIADADADLLEELKADKAE--LEAKKAELEAKLAELEALKAE 165

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462622367 2048 LKSEvKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLP 2096
Cdd:COG3883    166 LEAA-KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 513-621 5.95e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  513 LDEILSRIAKET----EEIKDLEEQLTEGQIAAnEALKKDLEgviSGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRL 588
Cdd:COG0542    395 IDEAAARVRMEIdskpEELDELERRLEQLEIEK-EALKKEQD---EASFERLAELRDELAELEEELEALKARWEAEKELI 470

                           90       100       110
                   ....*....|....*....|....*....|...
gi 2462622367  589 TEVEQERDQLEIVAMDAENMRKELAELESALQE 621
Cdd:COG0542    471 EEIQELKEELEQRYGKIPELEKELAELEEELAE 503
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1510-1730 6.27e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1510 LQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEA---LRLGETEVTEKCNHIREVKSLLEE 1586
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALeqeLAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1587 LSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQV 1666
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462622367 1667 AVLEEKLELENLQQISQQQKGEIEwqkQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 1730
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
 485-599 6.44e-03

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 40.27  E-value: 6.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  485 HSHMKAQKSGKEQQLDiMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEgqiaaneaLKKDLEGVISGLQEyLGTIK 564
Cdd:pfam13851   22 RNNLELIKSLKEEIAE-LKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEE--------LRKQLENYEKDKQS-LKNLK 91

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 2462622367  565 GQATQAQNECRKLRDEKETLLQRLTEVEQERDQLE 599
Cdd:pfam13851   92 ARLKVLEKELKDLKWEHEVLEQRFEKVERERDELY 126
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 255-621 7.00e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 7.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  255 VTTQDRQEAFERFsleEVERLERDLEKKMIETE---ELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDlNTK 331
Cdd:pfam17380  284 VSERQQQEKFEKM---EQERLRQEKEEKAREVErrrKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE-ERK 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  332 NELyaeidkapdespyigkSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDhmnLRGHTPLDTQLEDKEKKISAAQT 411
Cdd:pfam17380  360 REL----------------ERIRQEEIAMEISRMRELERLQMERQQKNERVRQE---LEAARKVKILEEERQRKIQQQKV 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  412 RLSELHDEIEKAEQQILRATEEfKQLEEAIQLKKEALDLELQMEKQKQEIAGKQKEikdlqiaidsldsKDPKHSHMKAQ 491
Cdd:pfam17380  421 EMEQIRAEQEEARQREVRRLEE-ERAREMERVRLEEQERQQQVERLRQQEEERKRK-------------KLELEKEKRDR 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  492 KSGKEQQLDImnkqyqqLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEalkkdlegvisglqeylgtiKGQATQAQ 571
Cdd:pfam17380  487 KRAEEQRRKI-------LEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE--------------------EERRREAE 539

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462622367  572 NECRKLR--DEKETLLQRLTEVEQERDQLEIVAMDAENMRkELAELESALQE 621
Cdd:pfam17380  540 EERRKQQemEERRRIQEQMRKATEERSRLEAMEREREMMR-QIVESEKARAE 590
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1432-1667 7.20e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 7.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1432 QLRSLQADAKDLEQHKIKQEEILKEINKivaakdsdfqcLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQ 1511
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAA-----------LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1512 AKRAELEKLKSQVTSQQQEMA----VLDRQLGHKKEELHLLQGSMVQAKAD---LQEALRLGETEVTEKCNHIREVKSLL 1584
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAellrALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1585 EELSFQKGELNVQISERKTQLTlikqEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKT 1664
Cdd:COG4942    167 AELEAERAELEALLAELEEERA----ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ...
gi 2462622367 1665 QVA 1667
Cdd:COG4942    243 TPA 245
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1286-2085 7.36e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.58  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1286 QSEKEMEELHHNIDDLLQEKKSLE-CE--VEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHedivdeiecIEKT 1362
Cdd:TIGR01612  901 EINKSIEEEYQNINTLKKVDEYIKiCEntKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDK---------FDNT 971

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1363 LLKRRSELREADRllaeaESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVkaDQQLRSLQADAKD 1442
Cdd:TIGR01612  972 LIDKINELDKAFK-----DASLNDYEAKNNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDI--EQKIEDANKNIPN 1044

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1443 LEQ------HKIkQEEILKEINK--------IVAAKDSDFQCLSKKKEKL----------------TEELQKLQKDIEMA 1492
Cdd:TIGR01612 1045 IEIaihtsiYNI-IDEIEKEIGKniellnkeILEEAEINITNFNEIKEKLkhynfddfgkeenikyADEINKIKDDIKNL 1123

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1493 ERNEDHHLQVLKESEvllqaKRAE--LEKLKSQVTSQQQemaVLDRQLGHKK-EELHLLQGSMVqakadlqealrlgeTE 1569
Cdd:TIGR01612 1124 DQKIDHHIKALEEIK-----KKSEnyIDEIKAQINDLED---VADKAISNDDpEEIEKKIENIV--------------TK 1181

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1570 VTEKCNHIREVKSLLEELS-FQKGEL------NVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNI------ 1636
Cdd:TIGR01612 1182 IDKKKNIYDEIKKLLNEIAeIEKDKTsleevkGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIkekspe 1261

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1637 ----LDMLQLENHELQGLKL-------------QHDQRVSELEKTQVAVLEEKLELENLQQISQQ-QKGEIEWQKQLLER 1698
Cdd:TIGR01612 1262 ieneMGIEMDIKAEMETFNIshdddkdhhiiskKHDENISDIREKSLKIIEDFSEESDINDIKKElQKNLLDAQKHNSDI 1341

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1699 DK--------------REIERMTAESRALQSCVEclsKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQS------- 1757
Cdd:TIGR01612 1342 NLylneianiynilklNKIKKIIDEVKEYTKEIE---ENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTlddkdid 1418

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1758 ----NLEKL-------ELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQ-----EKREAVNSLQEELANVQDHLNLAKQD 1821
Cdd:TIGR01612 1419 ecikKIKELknhilseESNIDTYFKNADENNENVLLLFKNIEMADNKSQhilkiKKDNATNDHDFNINELKEHIDKSKGC 1498

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1822 LLHTTKH-----QDVLLSEQTRlqKDISEWANRFEDCQ---KEEETKQQQLQVLqNEIEENKLKLVQQEMMFQRLQKERE 1893
Cdd:TIGR01612 1499 KDEADKNakaieKNKELFEQYK--KDVTELLNKYSALAiknKFAKTKKDSEIII-KEIKDAHKKFILEAEKSEQKIKEIK 1575

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1894 SEESKLETSKVtlkeQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTkrQLSEREQQLVEKS 1973
Cdd:TIGR01612 1576 KEKFRIEDDAA----KNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISSF--SIDSQDTELKENG 1649

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1974 GELLALQKEADSMRAdfsllRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLMANQKDLERRQMEISDAMRTLKSEVK 2053
Cdd:TIGR01612 1650 DNLNSLQEFLESLKD-----QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIE 1724

                          890       900       910
                   ....*....|....*....|....*....|..
gi 2462622367 2054 DEIRTSLKNLNQflpelpADLEAIlERNENLE 2085
Cdd:TIGR01612 1725 PTIENLISSFNT------NDLEGI-DPNEKLE 1749
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 612-863 7.92e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  612 LAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKeELEKVTRLTQLEQSALQAELEKERQALKnalg 691
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELA---- 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  692 kaqfseEKEQENSELHAKLKHLQDDnnlLKQQLKD-FQNHLNHVVDGLVRPEEVAARVDELRRklklgtgeMNIHSPSDv 770
Cdd:COG4942     87 ------ELEKEIAELRAELEAQKEE---LAELLRAlYRLGRQPPLALLLSPEDFLDAVRRLQY--------LKYLAPAR- 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  771 lgKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEfrqacERALEARMNFDKRQHEARIQQMENE 850
Cdd:COG4942    149 --REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE-----RQKLLARLEKELAELAAELAELQQE 221

                          250
                   ....*....|...
gi 2462622367  851 IHYLQENLKSMEE 863
Cdd:COG4942    222 AEELEALIARLEA 234
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 1720-1822 8.42e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 40.87  E-value: 8.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1720 LSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSL-HNDISAMQQQLQEKR 1798
Cdd:TIGR04320  252 PPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTaQNNLATAQAALANAE 331

                           90       100
                   ....*....|....*....|....
gi 2462622367 1799 EAVNSLQEELANVQDHLNLAKQDL 1822
Cdd:TIGR04320  332 ARLAKAKEALANLNADLAKKQAAL 355
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 529-728 8.80e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 8.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  529 DLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLeivamdaenm 608
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEER---------- 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  609 RKELAELESALQEQHEVNASLQ---------------QTQGDLSAYEAELEARLNLRDAEANQLKEELEKvtrlTQLEQS 673
Cdd:COG3883     85 REELGERARALYRSGGSVSYLDvllgsesfsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEA----KLAELE 160

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462622367  674 ALQAELEKERQALKNALgkaqfsEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQ 728
Cdd:COG3883    161 ALKAELEAAKAELEAQQ------AEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
46 PHA02562
endonuclease subunit; Provisional
 1772-2024 8.93e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1772 ELDQLNRDKlslhndISAMQQQLQEKREAVNSLQEELANVQDHLNlakqdllhttkhqdvllsEQTRLQKD-ISEWANRF 1850
Cdd:PHA02562   167 EMDKLNKDK------IRELNQQIQTLDMKIDHIQQQIKTYNKNIE------------------EQRKKNGEnIARKQNKY 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1851 EDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLET-SKV-----------TLKEQQHQLEKELT 1918
Cdd:PHA02562   223 DELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQfQKVikmyekggvcpTCTQQISEGPDRIT 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1919 DQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFsllrnqfl 1998
Cdd:PHA02562   303 KIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEF-------- 374

                          250       260
                   ....*....|....*....|....*.
gi 2462622367 1999 TERKKAEKQVASLKEALKIQRSQLEK 2024
Cdd:PHA02562   375 VDNAEELAKLQDELDKIVKTKSELVK 400
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1766-2174 9.10e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1766 VRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1845
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1846 WA--NRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSK 1923
Cdd:COG4717    128 LPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 1924 LDQvlskvlaAEERVRTLQEEerwCESLEKTLSQTKRQLseREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKK 2003
Cdd:COG4717    208 LAE-------LEEELEEAQEE---LEELEEELEQLENEL--EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTI 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2004 AEKQVASLKEALKIQRSQLEKNLLMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNEN 2083
Cdd:COG4717    276 AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367 2084 LEGELESLKENLPFTMNEGPFEEKlNFSQVHIMDEHWRGEALREKLRHREDRLKAQLR-HCMSKQAEVLIKGKRQTEGTL 2162
Cdd:COG4717    356 AEELEEELQLEELEQEIAALLAEA-GVEDEEELRAALEQAEEYQELKEELEELEEQLEeLLGELEELLEALDEEELEEEL 434

                          410
                   ....*....|..
gi 2462622367 2163 HSLRRQVDALGE 2174
Cdd:COG4717    435 EELEEELEELEE 446
PRK12704 PRK12704
phosphodiesterase; Provisional
 422-557 9.60e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 9.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  422 KAEQQILRATEEFKQL-----EEAIQLKKEALdLELQME--KQKQEIagkQKEIKDlqiaidsldsKDPKHSHMKAQKSG 494
Cdd:PRK12704    28 IAEAKIKEAEEEAKRIleeakKEAEAIKKEAL-LEAKEEihKLRNEF---EKELRE----------RRNELQKLEKRLLQ 93

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462622367  495 KEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKdlegvISGLQ 557
Cdd:PRK12704    94 KEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELER-----ISGLT 151
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 536-696 9.69e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 40.48  E-value: 9.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  536 EGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLeivamdaeNMRKELAEL 615
Cdd:pfam00529   64 EAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDL--------ARRRVLAPI 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  616 ESALQEQH-EVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 694
Cdd:pfam00529  136 GGISRESLvTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAKLDLERTEIRAP 215


                   ..
gi 2462622367  695 FS 696
Cdd:pfam00529  216 VD 217
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 394-755 9.82e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 40.97  E-value: 9.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  394 PLDTQLEDKEK-----KISAAQTRLSELHDEIEKAEQQ---ILRATEEFKQLEEaiQLKKEALDLELQMEKQKQEIAGKQ 465
Cdd:PRK04778    83 DIEEQLFEAEElndkfRFRKAKHEINEIESLLDLIEEDieqILEELQELLESEE--KNREEVEQLKDLYRELRKSLLANR 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  466 KEIKDlqiAIDSLdskdpkhshmkaqksgkEQQLDIMNKQYQQLESRLDEilSRIAKETEEIKDLEEQLTegqiaaneAL 545
Cdd:PRK04778   161 FSFGP---ALDEL-----------------EKQLENLEEEFSQFVELTES--GDYVEAREILDQLEEELA--------AL 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  546 KKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEK-----ETLLQRLTEVEQERDQLE--IVAMDAENMRKELAELESA 618
Cdd:PRK04778   211 EQIMEEIPELLKELQTELPDQLQELKAGYRELVEEGyhldhLDIEKEIQDLKEQIDENLalLEELDLDEAEEKNEEIQER 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622367  619 LQE-----QHEVNA--SLQQTQGDLSAYEAELEarlnlrdAEANQLKEELEKVTRLTQLEQSAL--QAELEKERQAL-KN 688
Cdd:PRK04778   291 IDQlydilEREVKArkYVEKNSDTLPDFLEHAK-------EQNKELKEEIDRVKQSYTLNESELesVRQLEKQLESLeKQ 363

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622367  689 ALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNhvvdGLVRPEEVA-ARVDELRRKL 755
Cdd:PRK04778   364 YDEITERIAEQEIAYSELQEELEEILKQLEEIEKEQEKLSEMLQ----GLRKDELEArEKLERYRNKL 427
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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