|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
68-730 |
3.81e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 87.80 E-value: 3.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 68 KRLQVTNPDLTQVVSLVVEREKQ----------------KSEAKDRKVLEIL----QVKDAKIQEFEQRESVLKQEINDL 127
Cdd:TIGR02168 179 RKLERTRENLDRLEDILNELERQlkslerqaekaerykeLKAELRELELALLvlrlEELREELEELQEELKEAEEELEEL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 128 VKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQ 204
Cdd:TIGR02168 259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILrerLANLERQLEELEAQLEELESKLDELAEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 205 EAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ----ELQNLYKQNST 280
Cdd:TIGR02168 339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIErleaRLERLEDRRER 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 281 HTAQQAELIQQLQVLNMDTQKV-----------LRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQL 349
Cdd:TIGR02168 419 LQQEIEELLKKLEEAELKELQAeleeleeeleeLQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 350 LQKEQENAKLKEKLQESQGAPLPLPQ-----ESDPDYSA----------------------------------------- 383
Cdd:TIGR02168 499 ENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAaieaalggrlqavvvenlnaakkaiaflkqnelgrvtflpl 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 384 --------QVPHRPSLSSLETLMVSQKSEIEY--------------------LQEKLKIANE-KLSENISANKG--FSRK 432
Cdd:TIGR02168 579 dsikgteiQGNDREILKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddLDNALELAKKlRPGYRIVTLDGdlVRPG 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 433 SIMTSAEGKHKEPPVKRSRSLspkssftdsEEL-QKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYR 511
Cdd:TIGR02168 659 GVITGGSAKTNSSILERRREI---------EELeEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 512 AVKEQLKQWEEgsgmTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMI----QKMNLEEELDELKVHISIDKAAI 587
Cdd:TIGR02168 730 ALRKDLARLEA----EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAeaeaEIEELEAQIEQLKEELKALREAL 805
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 588 QELNRCVAERREEQLFRSGEDDEVKRSTPEKngKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLK 667
Cdd:TIGR02168 806 DELRAELTLLNEEAANLRERLESLERRIAAT--ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462625061 668 QQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 730
Cdd:TIGR02168 884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
79-728 |
1.05e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.18 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 79 QVVSLVVEREKQKSEAKD-RKVLEILQVKDAKIQEfeqRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKfkdksq 157
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEElEREIEEERKRRDKLTE---EYAELKEELEDLRAELEEVDKEFAETRDELKDYREK------ 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 158 eikdtKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQ 237
Cdd:TIGR02169 394 -----LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 238 SKYNALSLQLSNKQTELIQKdmditlvRKELQELQnlykqnsthtaQQAELIQQLQVLNMDTQKVLR-NQEDVH--TAES 314
Cdd:TIGR02169 469 QELYDLKEEYDRVEKELSKL-------QRELAEAE-----------AQARASEERVRGGRAVEEVLKaSIQGVHgtVAQL 530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 315 ISYQKLYnelHICFETTKSNEamlrqsvtnLQDQLLQKEQENAKLKEKLQESQGAP---LPLPQESDPDYSAQVPHRPSL 391
Cdd:TIGR02169 531 GSVGERY---ATAIEVAAGNR---------LNNVVVEDDAVAKEAIELLKRRKAGRatfLPLNKMRDERRDLSILSEDGV 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 392 SSLETLMVSQKSEIEYLQeKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPP---VKRSRSLSPKSSFT--DSEELQ 466
Cdd:TIGR02169 599 IGFAVDLVEFDPKYEPAF-KYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKSgamTGGSRAPRGGILFSrsEPAELQ 677
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 467 KLRKAERKIENLEKALQ--LKSQEN------DELRDAHEKRKE---RLQMLQTNYRAVKEQLKQWEEgsgmtEIRKIKRA 535
Cdd:TIGR02169 678 RLRERLEGLKRELSSLQseLRRIENrldelsQELSDASRKIGEiekEIEQLEQEEEKLKERLEELEE-----DLSSLEQE 752
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 536 dpqqlrqedSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAI--QELNRCVAERREEQLFRSGEDDEVKR 613
Cdd:TIGR02169 753 ---------IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqAELSKLEEEVSRIEARLREIEQKLNR 823
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 614 STPEKNGKEMLEQTLQ-KVIELENRLKSFEKRsrkLKEGNKKLMKendfLKSLLKQQQEDTETREKELEQIIKGSKDVEK 692
Cdd:TIGR02169 824 LTLEKEYLEKEIQELQeQRIDLKEQIKSIEKE---IENLNGKKEE----LEEELEELEAALRDLESRLGDLKKERDELEA 896
|
650 660 670
....*....|....*....|....*....|....*..
gi 2462625061 693 ENTELQVKISELETEVTSLRRQVAEANA-LRNENEEL 728
Cdd:TIGR02169 897 QLRELERKIEELEAQIEKKRKRLSELKAkLEALEEEL 933
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
91-685 |
6.36e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.35 E-value: 6.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 91 KSEAKDRKVLEIL---QVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQ 167
Cdd:COG1196 219 KEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 168 NKEEQNRLV---IKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALS 244
Cdd:COG1196 299 RLEQDIARLeerRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 245 LQLSNKQTELIQKDMDITLVRKELQELQnlyKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLynel 324
Cdd:COG1196 379 EELEELAEELLEALRAAAELAAQLEELE---EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE---- 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 325 hicfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQE--SQGAPLPLPQESDPDYSAQVPhRPSLSSLETLMVSQK 402
Cdd:COG1196 452 ----AELEEEEEALLELLAELLEEAALLEAALAELLEELAEaaARLLLLLEAEADYEGFLEGVK-AALLLAGLRGLAGAV 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 403 SEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKE-----------PPVKRSRSLSPKSSFTDSEELQKLRKA 471
Cdd:COG1196 527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVAS 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 472 ERKIENL-EKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWN 550
Cdd:COG1196 607 DLREADArYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 551 ELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTlqk 630
Cdd:COG1196 687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE--- 763
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462625061 631 viELENRLKSFEKRSRKLKEGN-------KKLMKENDFLKSllkqQQEDTETREKELEQIIK 685
Cdd:COG1196 764 --ELERELERLEREIEALGPVNllaieeyEELEERYDFLSE----QREDLEEARETLEEAIE 819
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
178-745 |
1.01e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 178 KNLEEENKKLsTRCTDLLNDLEK-----------------LRKQEAHLRKEKYSTDakIKTFEDNLIEARKEVEVSQSKY 240
Cdd:TIGR02168 179 RKLERTRENL-DRLEDILNELERqlkslerqaekaerykeLKAELRELELALLVLR--LEELREELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 241 NALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQnstHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKL 320
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYA---LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 321 ynelhicfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDPDYSAQVPHRPSLSSLETLMVS 400
Cdd:TIGR02168 333 --------DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 401 QKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRslspkssftDSEELQKLRKAERKIENLEK 480
Cdd:TIGR02168 405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE---------LERLEEALEELREELEEAEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 481 ALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGM---------------TEIRKIKRADPQQLRQEDS 545
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlselisvdegyeAAIEAALGGRLQAVVVENL 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 546 DAVWNELAYFKRENQ------------------ELMIQKMNLEEELDELKVHISIDKAA----------------IQELN 591
Cdd:TIGR02168 556 NAAKKAIAFLKQNELgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNAL 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 592 RCVAERREEQLF-------------RSGEDDEVKRSTPE-----KNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNK 653
Cdd:TIGR02168 636 ELAKKLRPGYRIvtldgdlvrpggvITGGSAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELE 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 654 KLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPME 733
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795
|
650
....*....|..
gi 2462625061 734 KSHQSADRAKSE 745
Cdd:TIGR02168 796 EELKALREALDE 807
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
462-720 |
8.04e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 8.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 462 SEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMT----------EIRK 531
Cdd:TIGR02169 226 YELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvkekigeleaEIAS 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 532 IKRA-DPQQLRQEDSDA-----------VWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERRE 599
Cdd:TIGR02169 306 LERSiAEKERELEDAEErlakleaeidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 600 EQLFRSGEDDEVKRSTPEKNGK-----EMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTE 674
Cdd:TIGR02169 386 ELKDYREKLEKLKREINELKREldrlqEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2462625061 675 TREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANA 720
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
463-745 |
5.33e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 5.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 463 EELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEgsgmteirkikradpqqlrq 542
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-------------------- 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 543 edsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQlfrsgeddevkrstpeKNGKE 622
Cdd:COG1196 303 --------DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL----------------EEAEA 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 623 MLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKIS 702
Cdd:COG1196 359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2462625061 703 ELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSE 745
Cdd:COG1196 439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
88-739 |
5.96e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 54.38 E-value: 5.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 88 EKQKSEAKDRKVLEILQVKDAKIQEFEQRESvlKQEINDLVKRKIAVDEENAFLRKEfSDLEKKFKDKSQEIKDTKECVQ 167
Cdd:PTZ00121 1215 EEARKAEDAKKAEAVKKAEEAKKDAEEAKKA--EEERNNEEIRKFEEARMAHFARRQ-AAIKAEEARKADELKKAEEKKK 1291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 168 NKEEQNRLVIKNLEEENKKL--STRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNAlsl 245
Cdd:PTZ00121 1292 ADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA--- 1368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 246 qlSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLynelh 325
Cdd:PTZ00121 1369 --AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----- 1441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 326 icfETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQgaplplpqesdpdysaqvphrpslssletlmvsQKSEI 405
Cdd:PTZ00121 1442 ---EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAE---------------------------------EAKKA 1485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 406 EYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQK---LRKAE--RKIENLEK 480
Cdd:PTZ00121 1486 DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKadeLKKAEelKKAEEKKK 1565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 481 ALQLKSQEND---------ELRDAHEKRKERLQMLQTNYRAVK-EQLKQWEEgsgmteirkiKRADPQQLRQEDSDAVWN 550
Cdd:PTZ00121 1566 AEEAKKAEEDknmalrkaeEAKKAEEARIEEVMKLYEEEKKMKaEEAKKAEE----------AKIKAEELKKAEEEKKKV 1635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 551 ELAYFKRENQELMIQKMNLEEELD-----ELKVHISIDKAAIQELNRCVAERR--EEQLFRSGED----DEVKRSTPE-- 617
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAEELKKAEEENkikaaEEAKKAEEDKKKAEEAKKAEEDEKkaAEALKKEAEEakkaEELKKKEAEek 1715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 618 KNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGnKKLMKENDFLKSLLKQQQEDTETREKELEQIIKgsKDVEKENTEL 697
Cdd:PTZ00121 1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA-KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE--EELDEEDEKR 1792
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 2462625061 698 QVKISELETEVTSLRRQVAEANalrNENEELINPMEKSHQSA 739
Cdd:PTZ00121 1793 RMEVDKKIKDIFDNFANIIEGG---KEGNLVINDSKEMEDSA 1831
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
68-717 |
3.66e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.51 E-value: 3.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 68 KRLQVTNPDLTQVVSLVVEREKQ-KSEAKDRKVLEILQVKDAKIQEFEQRESVLKQeiNDLVKRKIAVDEENAFLRKEFS 146
Cdd:pfam02463 176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY--LKLNEERIDLLQELLRDEQEEI 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 147 DLEKKFKDKSQEIKDTKECVQNKEEQnrlVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNL 226
Cdd:pfam02463 254 ESSKQEIEKEEEKLAQVLKENKEEEK---EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 227 IEARKEVE-----------VSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVL 295
Cdd:pfam02463 331 KKEKEEIEelekelkeleiKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 296 NMDTQKVLRNQEDVHTAES---ISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLP 372
Cdd:pfam02463 411 LELARQLEDLLKEEKKEELeilEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 373 LPQESDPDYSAQVPHRPSLSSLETLMVSQKS----EIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVK 448
Cdd:pfam02463 491 SRQKLEERSQKESKARSGLKVLLALIKDGVGgriiSAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 449 RSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTE 528
Cdd:pfam02463 571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 529 IRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERRE-EQLFRSGE 607
Cdd:pfam02463 651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEElLADRVQEA 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 608 DDEVKRSTPEKNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGS 687
Cdd:pfam02463 731 QDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810
|
650 660 670
....*....|....*....|....*....|
gi 2462625061 688 KDVEKENTELQVKISELETEVTSLRRQVAE 717
Cdd:pfam02463 811 KEEAELLEEEQLLIEQEEKIKEEELEELAL 840
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
107-678 |
1.50e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 107 DAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKkfkdksqeikdTKECVQNKEEQNRLV---IKNLEEE 183
Cdd:PRK03918 192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE-----------LKEEIEELEKELESLegsKRKLEEK 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 184 NKKLSTRCTDLLNDLEKLRKQEAHLR--KEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDI 261
Cdd:PRK03918 261 IRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 262 TLVRKELQELQNLYkqnsthtaqqAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLYNELhicfETTKSNEAMLRQS 341
Cdd:PRK03918 341 EELKKKLKELEKRL----------EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL----EELEKAKEEIEEE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 342 VTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPqesdpdysaqVPHRP-SLSSLETLMVSQKSEIEYLQEKLKIANEKLS 420
Cdd:PRK03918 407 ISKITARIGELKKEIKELKKAIEELKKAKGKCP----------VCGRElTEEHRKELLEEYTAELKRIEKELKEIEEKER 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 421 EnISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIEnlEKALQLKSQENDELRDAHEKR- 499
Cdd:PRK03918 477 K-LRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLK--EKLIKLKGEIKSLKKELEKLEe 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 500 -KERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKV 578
Cdd:PRK03918 554 lKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 579 HISIDKAAIQELnrcvaERREEQLFRSGEDDEVKRSTPEKNGKEM-LEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMK 657
Cdd:PRK03918 634 ELAETEKRLEEL-----RKELEELEKKYSEEEYEELREEYLELSReLAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
|
570 580
....*....|....*....|.
gi 2462625061 658 ENDFLKSLLKQQQEDTETREK 678
Cdd:PRK03918 709 AKKELEKLEKALERVEELREK 729
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
472-1215 |
5.38e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 472 ERKIENLEKALQLKSQENDELRDAHE-KRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWN 550
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEElKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 551 ELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRsgEDDEVKRSTPEKNGKEMLEQTLQK 630
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEL--LKLERRKVDDEEKLKESEKEKKKA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 631 VIELENRLKSFEKRSRKLKEGNKKLMKENDflkslLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTS 710
Cdd:pfam02463 327 EKELKKEKEEIEELEKELKELEIKREAEEE-----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 711 LRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKVKFKAAKKNCSVGRHHTVL----NHS 786
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLketqLVK 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 787 IKVMSNVFENLSKDGWEDVSESSDSEAQTSQTLGTIIVETSQKISPTEDGKDQKESDPTEDSQTQGKEIVQTYLNIDGKT 866
Cdd:pfam02463 482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 867 PKDyfHDKNAKKPTFQKKNCKMQKSSHTAVPTRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTAELSVK 946
Cdd:pfam02463 562 ERQ--KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 947 EYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQvtslspsrsm 1026
Cdd:pfam02463 640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK---------- 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1027 dLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLESNKSFSEM 1106
Cdd:pfam02463 710 -EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1107 LQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVsRISETESAMAEIETAASK 1186
Cdd:pfam02463 789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE-KLAEEELERLEEEITKEE 867
|
730 740
....*....|....*....|....*....
gi 2462625061 1187 QLQELALQSEQVLEGAQKTLLLANEKVEE 1215
Cdd:pfam02463 868 LLQELLLKEEELEEQKLKDELESKEEKEK 896
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
920-1209 |
5.66e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.51 E-value: 5.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 920 LRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLaglrKEKEDLLK--KLESS 997
Cdd:pfam10174 420 LKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL----KEKVSALQpeLTEKE 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 998 SEITSLAEensqvtfpriQVTSLSPS-RSMDLEMKQLQYKLKNATNELTKQSSNVKTLKfELLAKEEHIKEMHEKISRME 1076
Cdd:pfam10174 496 SSLIDLKE----------HASSLASSgLKKDSKLKSLEIAVEQKKEECSKLENQLKKAH-NAEEAVRTNPEINDRIRLLE 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1077 RDITMKR-----------HLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKvSIDSLKQRLNVAVKEKSQY 1145
Cdd:pfam10174 565 QEVARYKeesgkaqaeveRLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIK-HGQQEMKKKGAQLLEEARR 643
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462625061 1146 EQMYQKSK----------EELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLLLA 1209
Cdd:pfam10174 644 REDNLADNsqqlqleelmGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAA 717
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
141-772 |
6.85e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 6.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 141 LRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKL-STRCTDLLNDLEKLRKQEAHLRKE--KYSTDA 217
Cdd:PTZ00121 1072 LKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEeAKKKAEDARKAEEARKAEDARKAEeaRKAEDA 1151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 218 KIKTFEDNLIEARKeVEVSQSKYNALSLQLSNKQTEL-----IQKDMDITLVrKELQELQNLYKQNSTHTAQQAELIQQL 292
Cdd:PTZ00121 1152 KRVEIARKAEDARK-AEEARKAEDAKKAEAARKAEEVrkaeeLRKAEDARKA-EAARKAEEERKAEEARKAEDAKKAEAV 1229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 293 QvlnmDTQKVLRNQEDVHTAESISYqklyNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLP 372
Cdd:PTZ00121 1230 K----KAEEAKKDAEEAKKAEEERN----NEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 373 LPQESDPDYSaqvphrpslssletlmvSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRS 452
Cdd:PTZ00121 1302 KKADEAKKKA-----------------EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 453 LSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHE-KRKERLQMLQTNYRAVKEQLKQWEEGSGMTEirK 531
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAE--E 1442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 532 IKRADPQQLRQEDSDAVWN--ELAYFKRENQELMiQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGED- 608
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEakKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEa 1521
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 609 ---DEVKRSTPEKNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKlmKENDFLKSLLKQQQEDTETREKELEQIIK 685
Cdd:PTZ00121 1522 kkaDEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK--KAEEDKNMALRKAEEAKKAEEARIEEVMK 1599
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 686 GSKDVEKENTELQVKISELETEVTSLRRqvaeANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKV 765
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKK 1675
|
....*..
gi 2462625061 766 KFKAAKK 772
Cdd:PTZ00121 1676 KAEEAKK 1682
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
529-760 |
8.19e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.98 E-value: 8.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 529 IRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGED 608
Cdd:PRK03918 151 VRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 609 DEVKRSTPEKNGKEMLEQTLQKVIE-LENRLKSFEKRSRKLKEGNKKLMKENDFLKSLlKQQQEDTETREKELEQIIKGS 687
Cdd:PRK03918 231 KELEELKEEIEELEKELESLEGSKRkLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDEL 309
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462625061 688 KDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEEL---INPMEKSHQSADRAKSEMATMKVRSGRYDCKT 760
Cdd:PRK03918 310 REIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELekrLEELEERHELYEEAKAKKEELERLKKRLTGLT 385
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
196-365 |
8.80e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 8.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 196 NDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLY 275
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 276 kqnsthtaqqAELIQQLQVL-NMDTQKVLRNQEDVHTAESIS--YQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQK 352
Cdd:COG4942 107 ----------AELLRALYRLgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
|
170
....*....|...
gi 2462625061 353 EQENAKLKEKLQE 365
Cdd:COG4942 177 EALLAELEEERAA 189
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
466-1241 |
9.64e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.97 E-value: 9.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 466 QKLRKAERKIENLEKALqlksqenDELRDAHEKRKERLQMLQ------TNYRAVKEQLKQWEEGSGMTEIRKIKRadpqq 539
Cdd:TIGR02168 172 ERRKETERKLERTRENL-------DRLEDILNELERQLKSLErqaekaERYKELKAELRELELALLVLRLEELRE----- 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 540 lrqedsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEqlfrsgeddevkrstpekn 619
Cdd:TIGR02168 240 -----------ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE------------------- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 620 gkemLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQV 699
Cdd:TIGR02168 290 ----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 700 KISELET--------------EVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKV 765
Cdd:TIGR02168 366 ELEELESrleeleeqletlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 766 KFKAAKKNCSVGRHHTVLN---------------------------HSIKVMSNVFENLSKDG----------------- 801
Cdd:TIGR02168 446 EEELEELQEELERLEEALEelreeleeaeqaldaaerelaqlqarlDSLERLQENLEGFSEGVkallknqsglsgilgvl 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 802 WEDVSESSDSEAQTSQTLG----TIIVETSQK-------ISPTEDGK---------DQKESDPTEDSQTQGKEIVQTYLN 861
Cdd:TIGR02168 526 SELISVDEGYEAAIEAALGgrlqAVVVENLNAakkaiafLKQNELGRvtflpldsiKGTEIQGNDREILKNIEGFLGVAK 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 862 IDGKTPKDYfhdKNAKKPTFQkkNCKMQKSSHTAVPTRV-NREKYKNITAQ---------------KSSSNIILLRERII 925
Cdd:TIGR02168 606 DLVKFDPKL---RKALSYLLG--GVLVVDDLDNALELAKkLRPGYRIVTLDgdlvrpggvitggsaKTNSSILERRREIE 680
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 926 SLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAE 1005
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1006 ENSQVTFPRIQVTSLSPSRSMDlEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHL 1085
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1086 IEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEksqyeqmYQKSKEELEKKDLKLTL 1165
Cdd:TIGR02168 840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE-------LEELSEELRELESKRSE 912
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462625061 1166 LVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLllanEKVEEFTTFVKALAKELQNDVHVVRRQIREL 1241
Cdd:TIGR02168 913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
447-1293 |
1.27e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.67 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 447 VKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAhEKRKERLQMLQTNYRAvkEQLKQWEEGSGM 526
Cdd:PTZ00121 1066 VGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEA-RKAEEAKKKAEDARKA--EEARKAEDARKA 1142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 527 TEIRKIKRADPQQLRQEDSDAVWNELAYfKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSG 606
Cdd:PTZ00121 1143 EEARKAEDAKRVEIARKAEDARKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAE 1221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 607 ED---------DEVKRSTPEKNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKEndflkslLKQQQEDTETRE 677
Cdd:PTZ00121 1222 DAkkaeavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE-------LKKAEEKKKADE 1294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 678 KELEQIIKGSKDVEKENTELQvKISELETEVTSLRRQvaeANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYD 757
Cdd:PTZ00121 1295 AKKAEEKKKADEAKKKAEEAK-KADEAKKKAEEAKKK---ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 758 CKTTMTKVKFKAAKKNCSVGRHHtvlnhsikvmsnvfENLSKDGWEDVSESSD-SEAQTSQTLGTIIVETSQKISPTEDG 836
Cdd:PTZ00121 1371 KKKEEAKKKADAAKKKAEEKKKA--------------DEAKKKAEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEA 1436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 837 KDQKESDPTEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTAvpTRVNREKYKNITAQKSSSN 916
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA--KKKADEAKKAAEAKKKADE 1514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 917 IILLRERIISLQQQNSvlQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLES 996
Cdd:PTZ00121 1515 AKKAEEAKKADEAKKA--EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA 1592
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 997 ---------SSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKL---KNATNELTKQSSNVKTLKFELLAKEEH 1064
Cdd:PTZ00121 1593 rieevmklyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaeeKKKAEELKKAEEENKIKAAEEAKKAEE 1672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1065 IKEMHEKISRMERDI-----TMKRHLIEDLKFRQ-KVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVA 1138
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEkkaaeALKKEAEEAKKAEElKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1139 VKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETaaSKQLQELALQSEQVLEGAQKTLLLANEKVEEFTT 1218
Cdd:PTZ00121 1753 EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV--DKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDS 1830
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462625061 1219 FVKalakELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1293
Cdd:PTZ00121 1831 AIK----EVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
149-736 |
1.48e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 46.17 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 149 EKKFKDKSQEIKDTKECVQNKEEQnrlvIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIE 228
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKNKEKE----LKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 229 ARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKEL----QELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVLR 304
Cdd:TIGR04523 108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIkkkeKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 305 NQEDVHTAESISYQKL-----YNELHICFETTKSNeamLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDP 379
Cdd:TIGR04523 188 NIDKIKNKLLKLELLLsnlkkKIQKNKSLESQISE---LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 380 DYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSENISANkgfsRKSIMTSAEGKHKEPPVKRSRSlspkssf 459
Cdd:TIGR04523 265 IKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE----LKSELKNQEKKLEEIQNQISQN------- 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 460 tdseeLQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQ 539
Cdd:TIGR04523 334 -----NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 540 LRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPE-- 617
Cdd:TIGR04523 409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQkq 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 618 ---KNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETRE----------------K 678
Cdd:TIGR04523 489 kelKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDfelkkenlekeideknK 568
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462625061 679 ELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSH 736
Cdd:TIGR04523 569 EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEN 626
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
66-293 |
3.12e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.43 E-value: 3.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 66 LWKRLQVTNPDLTQVVSLVVEREKQKSEAKDRKVLEILQVkDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEF 145
Cdd:TIGR02168 748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL-EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 146 SDLEKKFKDKSQEIKDTKECVQNKEEQ---NRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTF 222
Cdd:TIGR02168 827 ESLERRIAATERRLEDLEEQIEELSEDiesLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462625061 223 EDNLIEARKEVEVSQSKYNALSLQLSN-KQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQ 293
Cdd:TIGR02168 907 ESKRSELRRELEELREKLAQLELRLEGlEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
115-730 |
3.84e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 3.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 115 QRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDL 194
Cdd:TIGR04523 117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 195 LNDLEKLRKQEAHLRKEKySTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNL 274
Cdd:TIGR04523 197 LKLELLLSNLKKKIQKNK-SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 275 YKQNSTHTAQQAELIQQL--QVLNMDTQKVLRNQEDVHTaESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQK 352
Cdd:TIGR04523 276 LEQNNKKIKELEKQLNQLksEISDLNNQKEQDWNKELKS-ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNS 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 353 EQENAKLKEKLQESQGAPLPLPQESDpdysaqvphrpslssletlmvSQKSEIEYLQEKLKIANEKLSENISANKGFSRK 432
Cdd:TIGR04523 355 ESENSEKQRELEEKQNEIEKLKKENQ---------------------SYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 433 SIMTSAEGKHKEPPVKRSRslspkssftdseelQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRA 512
Cdd:TIGR04523 414 IKKLQQEKELLEKEIERLK--------------ETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 513 VKEQLKQWEEgsgmteirkikradpqqlrqedsdavwnELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNR 592
Cdd:TIGR04523 480 IKQNLEQKQK----------------------------ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 593 CVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQED 672
Cdd:TIGR04523 532 EKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462625061 673 TETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 730
Cdd:TIGR04523 612 ISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIK 669
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
166-367 |
4.00e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 4.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 166 VQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQE--AHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNAL 243
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 244 SLQLSNKQTEL--IQKDMDITLVRKELQELQnlykqnsthtAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLY 321
Cdd:COG3206 246 RAQLGSGPDALpeLLQSPVIQQLRAQLAELE----------AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRIL 315
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2462625061 322 NELHICFETTKSNEAMLRQSVTNLQDQLL---QKEQENAKLKEKLQESQ 367
Cdd:COG3206 316 ASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVAR 364
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
463-601 |
4.45e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 4.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 463 EELQKLRKAERKIENLEKALQLKSQENDELRDAHEKR---------KERLQMLQTNYRAVKEQLKQWEEGsgMTEIRKIK 533
Cdd:COG4717 92 ELQEELEELEEELEELEAELEELREELEKLEKLLQLLplyqelealEAELAELPERLEELEERLEELREL--EEELEELE 169
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462625061 534 ------RADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQ 601
Cdd:COG4717 170 aelaelQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE 243
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1029-1228 |
1.23e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.39 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1029 EMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHE-------KISRMERDITMKRHLIEDLKFRQKVNLESNK 1101
Cdd:COG1196 247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRRELEERLEELEEELA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1102 SFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIE 1181
Cdd:COG1196 327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2462625061 1182 TAASKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKALAKELQ 1228
Cdd:COG1196 407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
93-745 |
1.23e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.13 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 93 EAKDRKVLEILQVKDakiqeFEQRESVLKQEINDLVKRKIAVDEenaFLRKEfSDLEKKFKDKSQEIKDTKECVQNKEEQ 172
Cdd:PRK03918 145 ESREKVVRQILGLDD-----YENAYKNLGEVIKEIKRRIERLEK---FIKRT-ENIEELIKEKEKELEEVLREINEISSE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 173 NRLVIKNLEEENKKLStRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNAL-SLQLSNKQ 251
Cdd:PRK03918 216 LPELREELEKLEKEVK-ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkELKEKAEE 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 252 TELIQKDMDitlvrKELQELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVlrnqedvhtaesisyqklyNELHICFETT 331
Cdd:PRK03918 295 YIKLSEFYE-----EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-------------------EELKKKLKEL 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 332 KSNEAMLRQSVTNLQDqLLQKEQENAKLKEKLQESqgaplplpqesdpdysaqvphrpSLSSLETLMVSQKSEIEYLQEK 411
Cdd:PRK03918 351 EKRLEELEERHELYEE-AKAKKEELERLKKRLTGL-----------------------TPEKLEKELEELEKAKEEIEEE 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 412 LKIANEKLSEnISANKGFSRKSIMTSAEGKHKEPPVKRSrslspkssFTDSEELQKLRKAERKIENLEKALQLKSQENDE 491
Cdd:PRK03918 407 ISKITARIGE-LKKEIKELKKAIEELKKAKGKCPVCGRE--------LTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 492 LRdaheKRKERLQMLQTN------YRAVKEQLKQWEEGSGMTEIRKIKRAdpqqlrqedsdavWNELAYFKRENQELMIQ 565
Cdd:PRK03918 478 LR----KELRELEKVLKKeselikLKELAEQLKELEEKLKKYNLEELEKK-------------AEEYEKLKEKLIKLKGE 540
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 566 KMNLEEELDELKVHISiDKAAIQELNRCVAERREEQL-------FRSGEDDEVKRSTPEKNGKEMLEqTLQKVIELENRL 638
Cdd:PRK03918 541 IKSLKKELEKLEELKK-KLAELEKKLDELEEELAELLkeleelgFESVEELEERLKELEPFYNEYLE-LKDAEKELEREE 618
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 639 KSFEKRSRKLKEGNKKLMKENDFLKSLlkqqqedtetrEKELEQiiKGSKDVEKENTELQVKISELETEVTSLRRQVAEA 718
Cdd:PRK03918 619 KELKKLEEELDKAFEELAETEKRLEEL-----------RKELEE--LEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685
|
650 660
....*....|....*....|....*..
gi 2462625061 719 NALRNENEELINPMEKSHQSADRAKSE 745
Cdd:PRK03918 686 EKRREEIKKTLEKLKEELEEREKAKKE 712
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1058-1293 |
1.75e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1058 LLAKEEHIKEMHEKISRMERDITMKRHLIEDLKfrqkvnlesnKSFSEMLQNLDKKVKTLTEecsnKKVSIDSLKQRLNV 1137
Cdd:TIGR02168 672 ILERRREIEELEEKIEELEEKIAELEKALAELR----------KELEELEEELEQLRKELEE----LSRQISALRKDLAR 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1138 AVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIEtAASKQLQELALQSEQVLEGAQKTLLLANEKVEEft 1217
Cdd:TIGR02168 738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-AEIEELEAQIEQLKEELKALREALDELRAELTL-- 814
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462625061 1218 tfVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAE 1293
Cdd:TIGR02168 815 --LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
973-1240 |
1.81e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.61 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 973 IKKLN-LDLAGLRKEKEDLLKKLESSS--EITSLAEEnsqvtfprIQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSS 1049
Cdd:PRK05771 3 PVRMKkVLIVTLKSYKDEVLEALHELGvvHIEDLKEE--------LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLRE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1050 NVKTLKFELLAK------------EEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLE-----SNKSFSEMLQNLDK 1112
Cdd:PRK05771 75 EKKKVSVKSLEElikdveeelekiEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDlslllGFKYVSVFVGTVPE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1113 KVKTLTEECSNKKVS--IDSLKQRLNVA-VKEKSQYEQMYQ----------------KSKEELEKKDLKLTLLVSRISET 1173
Cdd:PRK05771 155 DKLEELKLESDVENVeyISTDKGYVYVVvVVLKELSDEVEEelkklgferleleeegTPSELIREIKEELEEIEKERESL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1174 ESAMAEIetaaSKQLQELALQSEQVLEG-AQKTLLLANEK-------------VEEFTTFVKALAKELQNDVHVVRRQIR 1239
Cdd:PRK05771 235 LEELKEL----AKKYLEELLALYEYLEIeLERAEALSKFLktdktfaiegwvpEDRVKKLKELIDKATGGSAYVEFVEPD 310
|
.
gi 2462625061 1240 E 1240
Cdd:PRK05771 311 E 311
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
94-257 |
2.10e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 94 AKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQN 173
Cdd:COG1579 3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 174 RLVIKN-----LEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLS 248
Cdd:COG1579 83 GNVRNNkeyeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162
|
....*....
gi 2462625061 249 NKQTELIQK 257
Cdd:COG1579 163 AEREELAAK 171
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
110-296 |
2.13e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.31 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 110 IQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQnrlvIKNLEEENKKLST 189
Cdd:TIGR04523 351 LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ----IKKLQQEKELLEK 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 190 RCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQ 269
Cdd:TIGR04523 427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKK 506
|
170 180
....*....|....*....|....*..
gi 2462625061 270 ELQNlykQNSTHTAQQAELIQQLQVLN 296
Cdd:TIGR04523 507 ELEE---KVKDLTKKISSLKEKIEKLE 530
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
466-600 |
2.17e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 466 QKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEgsgmteirKIKRADPQQLR---Q 542
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEA--------RIKKYEEQLGNvrnN 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462625061 543 EDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREE 600
Cdd:COG1579 89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE 146
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
983-1333 |
2.37e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.36 E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 983 LRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQlqYKLKNATNELTKQSSNVKTLKFELLAKE 1062
Cdd:PRK03918 174 IKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEL--EKLEKEVKELEELKEEIEELEKELESLE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1063 EHIKEMHEKISRMERDITMKRHLIEDLKFRQKvNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEK 1142
Cdd:PRK03918 252 GSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1143 SQYEQMyqksKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQ------ELALQSEQVLEGAQKTLLLANEKVEEF 1216
Cdd:PRK03918 331 KELEEK----EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElerlkkRLTGLTPEKLEKELEELEKAKEEIEEE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1217 TTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACK---TSTHKAQTLAASILNISR--SDLEEILDTEDQVEIEKTKID 1291
Cdd:PRK03918 407 ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRieKELKEIEEKERKLRKELRELE 486
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 2462625061 1292 AENDKEWMLYIQKLLEGQLPFASYLLEAV-LEKINEKKKLVEG 1333
Cdd:PRK03918 487 KVLKKESELIKLKELAEQLKELEEKLKKYnLEELEKKAEEYEK 529
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
615-730 |
2.70e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.22 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 615 TPEKNGKEMLEqTLQK-----VIELENRLKSFekRSRKLKEGNKKLMKENDFLKSLLKQQQEDTET----REKELEQIIK 685
Cdd:PRK05771 13 TLKSYKDEVLE-ALHElgvvhIEDLKEELSNE--RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEkkkvSVKSLEELIK 89
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2462625061 686 GSK----DVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELIN 730
Cdd:PRK05771 90 DVEeeleKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDLSL 138
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
461-726 |
2.71e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 461 DSEELQKLRKAERKIENLEKALQLKSQEN-----DELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRA 535
Cdd:pfam17380 304 EKEEKAREVERRRKLEEAEKARQAEMDRQaaiyaEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERL 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 536 dpQQLRQEDSDAVWNEL-AYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAER-------------REEQ 601
Cdd:pfam17380 384 --QMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERaremervrleeqeRQQQ 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 602 LFRSGEDDEVKRSTP-----EKNGKEMLEQTLQKVIE--LENRLKSF--EKRSRKLKEgnkKLMKENDflKSLLKQQQED 672
Cdd:pfam17380 462 VERLRQQEEERKRKKlelekEKRDRKRAEEQRRKILEkeLEERKQAMieEERKRKLLE---KEMEERQ--KAIYEEERRR 536
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462625061 673 TETREKELEQIIKGSKDVEKE---NTELQVKISELETEvTSLRRQVAEANALRNENE 726
Cdd:pfam17380 537 EAEEERRKQQEMEERRRIQEQmrkATEERSRLEAMERE-REMMRQIVESEKARAEYE 592
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
958-1210 |
2.93e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 958 QQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSseitslaeensqvtfpriqvtslspsrsmDLEMKQLQYKL 1037
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL-----------------------------ERRIAALARRI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1038 KNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDI-TMKRHLIEDLKFRQKVNLESNKSFsEMLQNLDKKVKT 1116
Cdd:COG4942 72 RALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVRRL-QYLKYLAPARRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1117 LTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEK----KDLKLTLLVSRISETESAMAEIETAAsKQLQELA 1192
Cdd:COG4942 151 QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEAlkaeRQKLLARLEKELAELAAELAELQQEA-EELEALI 229
|
250
....*....|....*...
gi 2462625061 1193 LQSEQVLEGAQKTLLLAN 1210
Cdd:COG4942 230 ARLEAEAAAAAERTPAAG 247
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
945-1296 |
2.98e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 2.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 945 VKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAeensqvtfpriQVTSLSPSR 1024
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-----------GYELLKEKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1025 SMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRM--ERDITMKRHlIEDLKFRQKvNLESNKS 1102
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK-IGELEAEIA-SLERSIA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1103 FSEM-LQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEkkdlkltLLVSRISETESAMAEIE 1181
Cdd:TIGR02169 312 EKEReLEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE-------DLRAELEEVDKEFAETR 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1182 TAASKQLQEL-ALQSE-QVLEGAQKTLLLANEKVEEfttfvkALAkELQNDVHVVRRQIRELK-KMKKNRDACKTSTHKA 1258
Cdd:TIGR02169 385 DELKDYREKLeKLKREiNELKRELDRLQEELQRLSE------ELA-DLNAAIAGIEAKINELEeEKEDKALEIKKQEWKL 457
|
330 340 350
....*....|....*....|....*....|....*...
gi 2462625061 1259 QTLAAsILNISRSDLEEILDTEDQVEIEKTKIDAENDK 1296
Cdd:TIGR02169 458 EQLAA-DLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
542-747 |
3.25e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 542 QEDSDAVWNELAYFKRENQELMIQKmnLEEELDELKVHISIDKAAIQELNrcvAERREEQLFRSGEDDEVKRStpekngK 621
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEE--LEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEA------Q 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 622 EMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKI 701
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2462625061 702 SELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMA 747
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1029-1205 |
3.43e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 3.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1029 EMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVN---------LES 1099
Cdd:COG3883 31 ELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSggsvsyldvLLG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1100 NKSFSEMLQNLD------KKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISET 1173
Cdd:COG3883 111 SESFSDFLDRLSalskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAE 190
|
170 180 190
....*....|....*....|....*....|..
gi 2462625061 1174 ESAMAEIETAASKQLQELALQSEQVLEGAQKT 1205
Cdd:COG3883 191 EAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
521-1297 |
3.65e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 3.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 521 EEGSGMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEE----ELDELKVHISIDKAAIQELNRCVAE 596
Cdd:pfam02463 159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKAleyyQLKEKLELEEEYLLYLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 597 RREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNK--------KLMKENDFLKSLLKQ 668
Cdd:pfam02463 239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEeelksellKLERRKVDDEEKLKE 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 669 QQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMAT 748
Cdd:pfam02463 319 SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 749 MKVRSGRYDCK----------TTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSDSEAQTSqt 818
Cdd:pfam02463 399 LKSEEEKEAQLllelarqledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE-- 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 819 lgtIIVETSQKISPTEDGKDQKESDPTEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSshTAVPT 898
Cdd:pfam02463 477 ---TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIS--TAVIV 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 899 RVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTaeLSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNL 978
Cdd:pfam02463 552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS--IAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 979 DLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFpriQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFEL 1058
Cdd:pfam02463 630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSE---VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1059 LAKEEHIKEMHEKISRMERDITMKRHLI--EDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLN 1136
Cdd:pfam02463 707 REKEELKKLKLEAEELLADRVQEAQDKIneELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1137 VAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEI--ETAASKQLQELALQSEQVLEGAQKTLLLANEKVE 1214
Cdd:pfam02463 787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIkeEELEELALELKEEQKLEKLAEEELERLEEEITKE 866
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1215 EFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAEN 1294
Cdd:pfam02463 867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAD 946
|
...
gi 2462625061 1295 DKE 1297
Cdd:pfam02463 947 EKE 949
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
467-750 |
4.46e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 467 KLRKAERKIENLEKALQLKSQENDELRDAHEK-RKERLQMLQtnYRAVKEQLKQWEegsgMTEIRKIKRADPQQLRQEDS 545
Cdd:TIGR02169 171 KKEKALEELEEVEENIERLDLIIDEKRQQLERlRREREKAER--YQALLKEKREYE----GYELLKEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 546 davwnelayfkrenqelmiQKMNLEEELDELKVHISIDKAAIQELNRcVAERREEQLFRSGEDDEVKRSTPEKNGKEMLE 625
Cdd:TIGR02169 245 -------------------QLASLEEELEKLTEEISELEKRLEEIEQ-LLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 626 QTLQKVIELENRLKSFEKRSRKLKEgnkklmkENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELE 705
Cdd:TIGR02169 305 SLERSIAEKERELEDAEERLAKLEA-------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD 377
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2462625061 706 TEVTSLRRQVAEA----NALRNENEELINPMEKSHQSADRAKSEMATMK 750
Cdd:TIGR02169 378 KEFAETRDELKDYreklEKLKREINELKRELDRLQEELQRLSEELADLN 426
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
439-724 |
4.67e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.56 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 439 EGKHKEPPVKRSRSLSPKSSFTDSEelqklrkAERKIENLEKALQLKsQENDELRDAHEKRKERLQMLQTnyravkeqlk 518
Cdd:PRK02224 197 EEKEEKDLHERLNGLESELAELDEE-------IERYEEQREQARETR-DEADEVLEEHEERREELETLEA---------- 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 519 qweegsgmtEIRKIkradpqqlrQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQElnrcVAERR 598
Cdd:PRK02224 259 ---------EIEDL---------RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEA----VEARR 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 599 EEQlfrSGEDDEVKRSTPEKngKEMLEQTLQKVIELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREK 678
Cdd:PRK02224 317 EEL---EDRDEELRDRLEEC--RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE 391
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 679 ELEQIIKG--------------SKDVEKENTELQVKISELETEVTSLRRQVAEANALRNE 724
Cdd:PRK02224 392 EIEELRERfgdapvdlgnaedfLEELREERDELREREAELEATLRTARERVEEAEALLEA 451
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
608-734 |
5.09e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.00 E-value: 5.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 608 DDEVKRSTPEKNGKEMLEQTlqkviELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIikgs 687
Cdd:COG2433 383 EELIEKELPEEEPEAEREKE-----HEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA---- 453
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2462625061 688 KDVEKENTELQVKISELETEVTSLRRQVAEanaLRNENEELINPMEK 734
Cdd:COG2433 454 RSEERREIRKDREISRLDREIERLERELEE---ERERIEELKRKLER 497
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
470-750 |
5.11e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 470 KAERKIENLEKA-LQLKSQ-----ENDELRDAHEKRKERLQmlqTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQE 543
Cdd:PRK04863 349 KIERYQADLEELeERLEEQnevveEADEQQEENEARAEAAE---EEVDELKSQLADYQQALDVQQTRAIQYQQAVQALER 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 544 DSDavWNELAYFKRENQELMI-----QKMNLEEELDELKVHISIDKAAiqelnrcvAERREE--QLFRSGEDdEVKRSTP 616
Cdd:PRK04863 426 AKQ--LCGLPDLTADNAEDWLeefqaKEQEATEELLSLEQKLSVAQAA--------HSQFEQayQLVRKIAG-EVSRSEA 494
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 617 EKNGKEMLEQ------TLQKVIELENRLKSFEKRSRK-------LKEGNKKLMKE---NDFLKSLLKQQQEDTETREKEL 680
Cdd:PRK04863 495 WDVARELLRRlreqrhLAEQLQQLRMRLSELEQRLRQqqraerlLAEFCKRLGKNlddEDELEQLQEELEARLESLSESV 574
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 681 EQIIKGSKDVEKENTELQVKISELETE----------VTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMK 750
Cdd:PRK04863 575 SEARERRMALRQQLEQLQARIQRLAARapawlaaqdaLARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARK 654
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1028-1297 |
6.33e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.08 E-value: 6.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1028 LEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKfrqkvnlesnksfsEML 1107
Cdd:COG1196 225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ--------------AEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1108 QNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQ 1187
Cdd:COG1196 291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 1188 LQELALQSEQVLEGAQKTLLLANEKVEEfttfvkalAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILN 1267
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAEL--------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442
|
250 260 270
....*....|....*....|....*....|
gi 2462625061 1268 ISRSDLEEILDTEDQVEIEKTKIDAENDKE 1297
Cdd:COG1196 443 ALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
90-295 |
7.25e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 7.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 90 QKSEAKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLvkrkiavDEENAFLRKEFSDLEKKFK---DKSQEIKDTKECV 166
Cdd:pfam07888 48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAEL-------KEELRQSREKHEELEEKYKelsASSEELSEEKDAL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 167 QNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLR---KQEAHLRKEKYSTDAKIKTfednliearkEVEVSQSKYNAL 243
Cdd:pfam07888 121 LAQRAAHEARIRELEEDIKTLTQRVLERETELERMKeraKKAGAQRKEEEAERKQLQA----------KLQQTEEELRSL 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2462625061 244 SLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVL 295
Cdd:pfam07888 191 SKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSL 242
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
427-577 |
8.92e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.23 E-value: 8.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462625061 427 KGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKalqlksqENDELRDAHEKRKERLQML 506
Cdd:COG2433 374 RGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEA-------EVEELEAELEEKDERIERL 446
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90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462625061 507 QTNYRAVKEqlkqwEEGSGMTEIRKIKRadpqqlRQEDSDAVWNELAYFKRENQElmiqkmnLEEELDELK 577
Cdd:COG2433 447 ERELSEARS-----EERREIRKDREISR------LDREIERLERELEEERERIEE-------LKRKLERLK 499
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