NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2756245149|ref|XP_066163322|]
View 

pyrophosphate-energized membrane proton pump 3 isoform X2 [Oryza sativa Japonica Group]

Protein Classification

sodium/proton-translocating pyrophosphatase( domain architecture ID 10010753)

sodium/proton-translocating pyrophosphatase such as K(+)-stimulated pyrophosphate-energized sodium pump and K(+)-insensitive pyrophosphate-energized proton pump, which utilize the energy of pyrophosphate hydrolysis as the driving force for sodium/proton movement across the membrane

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PLN02277 PLN02277
H(+) -translocating inorganic pyrophosphatase
70-799 0e+00

H(+) -translocating inorganic pyrophosphatase


:

Pssm-ID: 177916  Cd Length: 730  Bit Score: 1431.12  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  70 CICTLSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVILGIYLFRSTTPQQEASGVGR 149
Cdd:PLN02277    1 TVCIISLLFSLYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYGTISKMAVVLAFVILGIYLFRSLTPQQEAAGLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 150 TTSAYITVASFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFYVW 229
Cdd:PLN02277   81 ATSAYITVASFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMTVLGVAILYATFYVW 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 230 LEVDSPGSMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 309
Cdd:PLN02277  161 LGVDSPGGMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 310 ARGADLFESIAAEIISAMILGGTMAQRCKIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDSGLISPIEDPMAIMQKG 389
Cdd:PLN02277  241 ARGADLFESIAAEIISAMILGGTMAKRCKIEDPSGFILFPLVVHSFDLVVSSIGILSIKGTRDSSVKSPVEDPMAVLQKG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 390 YSITILLAVVTFGVSTRWLLYTEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGV 469
Cdd:PLN02277  321 YSVTIILAVVTFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYAFVWISQYYTDYKYEPVRTLALASTTGHGTNIIAGV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 470 SLGLESTALPVLVISVAIISAFWLGHTSGLVDESGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 549
Cdd:PLN02277  401 SLGLESTALPVLVISVAIISAYWLGNTSGLVDENGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 550 PESVREITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAAFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 629
Cdd:PLN02277  481 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFAGVPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 630 ACSAVGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIFRMLGHATGRPLL 709
Cdd:PLN02277  561 ACAAVGRTAQEVVNEVRRQFAERPGIMDYKEKPDYGRCVAIVASAALREMIKPGALAVISPIVVGLVFRILGYATGQPLL 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 710 GAKVVAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 789
Cdd:PLN02277  641 GAKVVAGMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 720
                         730
                  ....*....|
gi 2756245149 790 ITLVMAPIFL 799
Cdd:PLN02277  721 ITLVMAPMFL 730
 
Name Accession Description Interval E-value
PLN02277 PLN02277
H(+) -translocating inorganic pyrophosphatase
70-799 0e+00

H(+) -translocating inorganic pyrophosphatase


Pssm-ID: 177916  Cd Length: 730  Bit Score: 1431.12  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  70 CICTLSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVILGIYLFRSTTPQQEASGVGR 149
Cdd:PLN02277    1 TVCIISLLFSLYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYGTISKMAVVLAFVILGIYLFRSLTPQQEAAGLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 150 TTSAYITVASFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFYVW 229
Cdd:PLN02277   81 ATSAYITVASFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMTVLGVAILYATFYVW 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 230 LEVDSPGSMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 309
Cdd:PLN02277  161 LGVDSPGGMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 310 ARGADLFESIAAEIISAMILGGTMAQRCKIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDSGLISPIEDPMAIMQKG 389
Cdd:PLN02277  241 ARGADLFESIAAEIISAMILGGTMAKRCKIEDPSGFILFPLVVHSFDLVVSSIGILSIKGTRDSSVKSPVEDPMAVLQKG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 390 YSITILLAVVTFGVSTRWLLYTEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGV 469
Cdd:PLN02277  321 YSVTIILAVVTFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYAFVWISQYYTDYKYEPVRTLALASTTGHGTNIIAGV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 470 SLGLESTALPVLVISVAIISAFWLGHTSGLVDESGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 549
Cdd:PLN02277  401 SLGLESTALPVLVISVAIISAYWLGNTSGLVDENGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 550 PESVREITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAAFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 629
Cdd:PLN02277  481 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFAGVPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 630 ACSAVGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIFRMLGHATGRPLL 709
Cdd:PLN02277  561 ACAAVGRTAQEVVNEVRRQFAERPGIMDYKEKPDYGRCVAIVASAALREMIKPGALAVISPIVVGLVFRILGYATGQPLL 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 710 GAKVVAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 789
Cdd:PLN02277  641 GAKVVAGMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 720
                         730
                  ....*....|
gi 2756245149 790 ITLVMAPIFL 799
Cdd:PLN02277  721 ITLVMAPMFL 730
H_PPase pfam03030
Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved ...
74-794 0e+00

Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved in establishing the H+ electrochemical potential difference between the vacuole lumen and the cell cytosol. Vacuolar-type H(+)-translocating inorganic pyrophosphatases have long been considered to be restricted to plants and to a few species of photo-trophic bacteria. However, in recent investigations, these pyrophosphatases have been found in organizms as disparate as thermophilic Archaea and parasitic protists.


Pssm-ID: 427106  Cd Length: 663  Bit Score: 928.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  74 LSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVILGIYlfrsttpqqeasgvgrttsA 153
Cdd:pfam03030   2 LALLFALYLARWVLKQPAGTEKMQEIAGAIQEGAMAFLKRQYKTLAIFAVVIAVLLFLLL-------------------G 62
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 154 YITVASFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFyvwlevd 233
Cdd:pfam03030  63 LLTAVAFLVGALFSALAGYIGMRVATRANVRTANAARKGLGKALRVAFRGGAVMGLLVVGLGLLGLSLLYLIF------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 234 sPGSMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGA 313
Cdd:pfam03030 136 -GDGLDDETAPEALVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGA 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 314 DLFESIAAEIISAMILGGTMAQrckIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDSGlisPIEDPMAIMQKGYSIT 393
Cdd:pfam03030 215 DLFESYVVTIVAAMVLGALAAS---PELGVKLVLFPLLIAAVGIIASIIGTFFVRTKANPK---GKEDPMKALNRGLWVS 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 394 ILLAVVTFGVSTRWLLYTEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGVSLGL 473
Cdd:pfam03030 289 AILSIVLIFFASYLLLGAGGAGFGWWGLFLAILIGLVAGALIGLITEYYTSTSYRPVREIAEASETGAATNIISGLAVGM 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 474 ESTALPVLVISVAIISAFWLGhtsglvdesgnptgGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESV 553
Cdd:pfam03030 369 ESTALPVLVIAAAILIAYLLA--------------GLYGIALAAVGMLSTAGITLAVDAYGPIADNAGGIAEMSGLPEEV 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 554 REITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAAFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAWACSA 633
Cdd:pfam03030 435 REITDALDAVGNTTKAIGKGFAIGSAALAALALFAAYIEEVGAVLGGPLLVLDLLNPPVLVGLLIGGMLPFLFSALTMQA 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 634 VGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIFrmlghatgrpllGAKV 713
Cdd:pfam03030 515 VGRAAGRMVEEVRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIVVGFLL------------GPEA 582
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 714 VAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLV 793
Cdd:pfam03030 583 LGGLLAGATVSGVLLAIFMANAGGAWDNAKKYIEDGNHGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMSIVSLV 662

                  .
gi 2756245149 794 M 794
Cdd:pfam03030 663 F 663
OVP1 COG3808
Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];
86-799 0e+00

Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];


Pssm-ID: 443021  Cd Length: 660  Bit Score: 865.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  86 VLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVIlgiylfrsttpqqeasGVGRTTSAYITVASFLLGAL 165
Cdd:COG3808     1 VLKQPAGTERMQEIAGAIQEGAMAYLKRQYKTLAIFAVVIAVLL----------------ALLLGGGGWLTAIAFLIGAV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 166 CSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFYVWLEvdspgsmkvtDLPL 245
Cdd:COG3808    65 FSALAGYIGMRVATRANVRTANAARKGLNKALKVAFRGGAVMGLLVVGLGLLGLSLLYLIFGGFLE----------TAPE 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 246 LLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 325
Cdd:COG3808   135 VLVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVVTIVA 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 326 AMILGGTMAqrcKIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDsglispiEDPMAIMQKGYSITILLAVVTFGVST 405
Cdd:COG3808   215 AMVLGALAF---GAALGVALVLLPLLIAAVGIIASIIGIFFVRTKEG-------ANPMKALNRGTYVTAVLSAVATYFVT 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 406 RWLLytEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGVSLGLESTALPVLVISV 485
Cdd:COG3808   285 YLLL--PGSGFGWLGLFLAVLIGLVAGALIGLITEYYTSTEYRPVREIAEASETGPATNIISGLAVGMESTALPVLVIAA 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 486 AIISAFWLGhtsglvdeSGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDILDAVGN 565
Cdd:COG3808   363 AILVAYLLA--------GGGFAPGLYGIALAAVGMLSTTGITVAVDAYGPIADNAGGIAEMSGLPPEVREITDALDAVGN 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 566 TTKATTKGFAIGSAALASFLLFSAYMDEVA-AFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAWACSAVGRTAQEVVNE 644
Cdd:COG3808   435 TTKAITKGFAIGSAALAALALFAAYIEEVGiALGEALLLSLDLLNPPVLVGLFIGGMLPFLFSALAMQAVGRAAGAMVEE 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 645 VRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIfrmlghatgrplLGAKVVAAMLMFATVS 724
Cdd:COG3808   515 VRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIAVGFL------------LGPEALGGLLAGAIVS 582
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2756245149 725 GILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPIFL 799
Cdd:COG3808   583 GVLLAIFMANAGGAWDNAKKYIEDGNLGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMNIVSLVIAPLFV 657
V_PPase TIGR01104
vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases ...
66-798 0e+00

vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases from eukaryotes (predominantly plants), archaea and bacteria. It is an integral membrane protein and is suggested to have about 15 membrane spanning domains. Proton translocating inorganic pyrophosphatase, like H(+)-ATPase, acidifies the vacuoles and is pivotal to the vacuolar secondary active transport systems in plants. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273444  Cd Length: 695  Bit Score: 597.93  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  66 LFVFCICTLSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILAlVILGIYLfrsttpqqeas 145
Cdd:TIGR01104   3 ILIPVCAVIGIAYAVLQWVWVSRVKLGTAKMAEIQQAISEGATAFLFTEYKYVAVFMVAFA-VLIFVFL----------- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 146 GVGRTTSAYITVAsFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYAT 225
Cdd:TIGR01104  71 GSREGFSDFSTVA-FLLGAVTSLLAGYLGMKIATYANARTTLEARKGVGKALIVAFRSGAVMGFLLAGLGLLVLYITILV 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 226 FYVWLEVDSPGSMKVtdlpllLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNV 305
Cdd:TIGR01104 150 FKIYYGDDWEGLFEP------ITGYGFGASSMALFGRVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNV 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 306 GDCAARGADLFESIAAEIISAMILGGTMAqrckIEDPSGFILFplvvhSFDLVISSVGILSIRGTRDSGLISPIEDPMAI 385
Cdd:TIGR01104 224 GDIAGMGADLFESYAESSCAALVLASISS----FGLPHDFTAM-----LYPLALSSVGILVCLLTTLFVKIKPVKEIEPA 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 386 MQKGYSITILLAVVTFGVSTRWLLYT--------EQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSS 457
Cdd:TIGR01104 295 LKKQLIISTVLMTVGVAVISWVALPTgftifnfgTQKEVSNWQLFLCVAVGLWAGLLIGFVTEYYTSNAYSPVQDVADSC 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 458 STGHGTNIIAGVSLGLESTALPVLVISVAIISAFWLghtsglvdesgnptGGLFGTAVATMGMLSTAAYVLTMDMFGPIA 537
Cdd:TIGR01104 375 RTGAATNVIFGLALGYKSVIIPIFAIAASIIVSFSF--------------AGMYGIAMAALGMLSTAGTGLAIDAYGPIS 440
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 538 DNAGGIVEMSQQPESVREITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAafaqlpFKEVDIAIPEVFVGGL 617
Cdd:TIGR01104 441 DNAGGIAEMAGLPHRVRERTDALDAVGNTTAAIGKGFAIGSAALVALALFGAFVSRAV------ITTVDVLTPKVFIGLF 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 618 LGSMLIFLFSAWACSAVGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIF 697
Cdd:TIGR01104 515 VGAMLPYWFSSMTMKSVGRAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGLLVMLTPLIVGFLF 594
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 698 rmlghatgrpllGAKVVAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGA-----LGGKGSESHKAAVTGDTVGDPF 772
Cdd:TIGR01104 595 ------------GVETLSGVLAGVLVSGVQIAISASNTGGAWDNAKKYIEAGSeharsLGPKGSEAHKAAVIGDTVGDPL 662
                         730       740
                  ....*....|....*....|....*.
gi 2756245149 773 KDTAGPSIHVLIKMLATITLVMAPIF 798
Cdd:TIGR01104 663 KDTSGPSLNILIKLMAVESLVFAPFF 688
 
Name Accession Description Interval E-value
PLN02277 PLN02277
H(+) -translocating inorganic pyrophosphatase
70-799 0e+00

H(+) -translocating inorganic pyrophosphatase


Pssm-ID: 177916  Cd Length: 730  Bit Score: 1431.12  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  70 CICTLSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVILGIYLFRSTTPQQEASGVGR 149
Cdd:PLN02277    1 TVCIISLLFSLYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYGTISKMAVVLAFVILGIYLFRSLTPQQEAAGLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 150 TTSAYITVASFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFYVW 229
Cdd:PLN02277   81 ATSAYITVASFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMTVLGVAILYATFYVW 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 230 LEVDSPGSMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 309
Cdd:PLN02277  161 LGVDSPGGMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 310 ARGADLFESIAAEIISAMILGGTMAQRCKIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDSGLISPIEDPMAIMQKG 389
Cdd:PLN02277  241 ARGADLFESIAAEIISAMILGGTMAKRCKIEDPSGFILFPLVVHSFDLVVSSIGILSIKGTRDSSVKSPVEDPMAVLQKG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 390 YSITILLAVVTFGVSTRWLLYTEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGV 469
Cdd:PLN02277  321 YSVTIILAVVTFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYAFVWISQYYTDYKYEPVRTLALASTTGHGTNIIAGV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 470 SLGLESTALPVLVISVAIISAFWLGHTSGLVDESGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 549
Cdd:PLN02277  401 SLGLESTALPVLVISVAIISAYWLGNTSGLVDENGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 550 PESVREITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAAFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 629
Cdd:PLN02277  481 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFAGVPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 630 ACSAVGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIFRMLGHATGRPLL 709
Cdd:PLN02277  561 ACAAVGRTAQEVVNEVRRQFAERPGIMDYKEKPDYGRCVAIVASAALREMIKPGALAVISPIVVGLVFRILGYATGQPLL 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 710 GAKVVAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 789
Cdd:PLN02277  641 GAKVVAGMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 720
                         730
                  ....*....|
gi 2756245149 790 ITLVMAPIFL 799
Cdd:PLN02277  721 ITLVMAPMFL 730
H_PPase pfam03030
Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved ...
74-794 0e+00

Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved in establishing the H+ electrochemical potential difference between the vacuole lumen and the cell cytosol. Vacuolar-type H(+)-translocating inorganic pyrophosphatases have long been considered to be restricted to plants and to a few species of photo-trophic bacteria. However, in recent investigations, these pyrophosphatases have been found in organizms as disparate as thermophilic Archaea and parasitic protists.


Pssm-ID: 427106  Cd Length: 663  Bit Score: 928.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  74 LSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVILGIYlfrsttpqqeasgvgrttsA 153
Cdd:pfam03030   2 LALLFALYLARWVLKQPAGTEKMQEIAGAIQEGAMAFLKRQYKTLAIFAVVIAVLLFLLL-------------------G 62
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 154 YITVASFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFyvwlevd 233
Cdd:pfam03030  63 LLTAVAFLVGALFSALAGYIGMRVATRANVRTANAARKGLGKALRVAFRGGAVMGLLVVGLGLLGLSLLYLIF------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 234 sPGSMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGA 313
Cdd:pfam03030 136 -GDGLDDETAPEALVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGA 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 314 DLFESIAAEIISAMILGGTMAQrckIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDSGlisPIEDPMAIMQKGYSIT 393
Cdd:pfam03030 215 DLFESYVVTIVAAMVLGALAAS---PELGVKLVLFPLLIAAVGIIASIIGTFFVRTKANPK---GKEDPMKALNRGLWVS 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 394 ILLAVVTFGVSTRWLLYTEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGVSLGL 473
Cdd:pfam03030 289 AILSIVLIFFASYLLLGAGGAGFGWWGLFLAILIGLVAGALIGLITEYYTSTSYRPVREIAEASETGAATNIISGLAVGM 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 474 ESTALPVLVISVAIISAFWLGhtsglvdesgnptgGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESV 553
Cdd:pfam03030 369 ESTALPVLVIAAAILIAYLLA--------------GLYGIALAAVGMLSTAGITLAVDAYGPIADNAGGIAEMSGLPEEV 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 554 REITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAAFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAWACSA 633
Cdd:pfam03030 435 REITDALDAVGNTTKAIGKGFAIGSAALAALALFAAYIEEVGAVLGGPLLVLDLLNPPVLVGLLIGGMLPFLFSALTMQA 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 634 VGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIFrmlghatgrpllGAKV 713
Cdd:pfam03030 515 VGRAAGRMVEEVRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIVVGFLL------------GPEA 582
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 714 VAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLV 793
Cdd:pfam03030 583 LGGLLAGATVSGVLLAIFMANAGGAWDNAKKYIEDGNHGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMSIVSLV 662

                  .
gi 2756245149 794 M 794
Cdd:pfam03030 663 F 663
OVP1 COG3808
Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];
86-799 0e+00

Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];


Pssm-ID: 443021  Cd Length: 660  Bit Score: 865.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  86 VLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVIlgiylfrsttpqqeasGVGRTTSAYITVASFLLGAL 165
Cdd:COG3808     1 VLKQPAGTERMQEIAGAIQEGAMAYLKRQYKTLAIFAVVIAVLL----------------ALLLGGGGWLTAIAFLIGAV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 166 CSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFYVWLEvdspgsmkvtDLPL 245
Cdd:COG3808    65 FSALAGYIGMRVATRANVRTANAARKGLNKALKVAFRGGAVMGLLVVGLGLLGLSLLYLIFGGFLE----------TAPE 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 246 LLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 325
Cdd:COG3808   135 VLVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVVTIVA 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 326 AMILGGTMAqrcKIEDPSGFILFPLVVHSFDLVISSVGILSIRGTRDsglispiEDPMAIMQKGYSITILLAVVTFGVST 405
Cdd:COG3808   215 AMVLGALAF---GAALGVALVLLPLLIAAVGIIASIIGIFFVRTKEG-------ANPMKALNRGTYVTAVLSAVATYFVT 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 406 RWLLytEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGVSLGLESTALPVLVISV 485
Cdd:COG3808   285 YLLL--PGSGFGWLGLFLAVLIGLVAGALIGLITEYYTSTEYRPVREIAEASETGPATNIISGLAVGMESTALPVLVIAA 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 486 AIISAFWLGhtsglvdeSGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDILDAVGN 565
Cdd:COG3808   363 AILVAYLLA--------GGGFAPGLYGIALAAVGMLSTTGITVAVDAYGPIADNAGGIAEMSGLPPEVREITDALDAVGN 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 566 TTKATTKGFAIGSAALASFLLFSAYMDEVA-AFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAWACSAVGRTAQEVVNE 644
Cdd:COG3808   435 TTKAITKGFAIGSAALAALALFAAYIEEVGiALGEALLLSLDLLNPPVLVGLFIGGMLPFLFSALAMQAVGRAAGAMVEE 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 645 VRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIfrmlghatgrplLGAKVVAAMLMFATVS 724
Cdd:COG3808   515 VRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIAVGFL------------LGPEALGGLLAGAIVS 582
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2756245149 725 GILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPIFL 799
Cdd:COG3808   583 GVLLAIFMANAGGAWDNAKKYIEDGNLGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMNIVSLVIAPLFV 657
hppA PRK00733
membrane-bound proton-translocating pyrophosphatase; Validated
86-798 0e+00

membrane-bound proton-translocating pyrophosphatase; Validated


Pssm-ID: 234827 [Multi-domain]  Cd Length: 666  Bit Score: 830.94  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  86 VLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILALVILGIYLFrsttpqqeasgvgrTTSAYITVASFLLGAL 165
Cdd:PRK00733    1 VLKQPAGTERMQEIAGAIQEGAMAYLKRQYKTIAIFGVVVAVLLFLPAGG--------------LFLGWLTAVAFLVGAV 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 166 CSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYATFyvwlevdsPGSMKVTDLPL 245
Cdd:PRK00733   67 FSALAGYIGMRVATRANVRTAQAARKGLGKALKVAFRGGAVMGLLVVGLGLLGVAGLYLVF--------GLGANPDDAPD 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 246 LLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 325
Cdd:PRK00733  139 ALVGFGFGASLIALFARVGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMGADLFESYAVTIVA 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 326 AMILGGTMAQrckIEDPSGFILFPLVVHSFDLVISSVGILSIRgtrdsglISPIEDPMAIMQKGYSITILLAVVTFGVST 405
Cdd:PRK00733  219 AMVLGAAAAD---AAFGVAGVLFPLLIAAVGIIASIIGIFFVR-------LGKGGNPMKALNRGLIVTAVLSIVLTYFAT 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 406 RWLLYTEQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGVSLGLESTALPVLVISV 485
Cdd:PRK00733  289 YWLLGDGADGFTWLNLFGAVLIGLVVGALIGLITEYYTSTEYRPVKEIAEASRTGPATNIISGLAVGMESTALPVLVIVA 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 486 AIISAFWLghtsglvdesGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDILDAVGN 565
Cdd:PRK00733  369 AILGAYLL----------GMAGAGLYGIALAAVGMLSTAGIIVAVDAYGPITDNAGGIAEMAGLPPEVRKITDALDAVGN 438
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 566 TTKATTKGFAIGSAALASFLLFSAYMDEVA-AFAQLPFKEVDIAIPEVFVGGLLGSMLIFLFSAWACSAVGRTAQEVVNE 644
Cdd:PRK00733  439 TTKAVTKGFAIGSAALAALALFAAYIDELAgLLGGGGILSLDLSNPYVLVGLLIGGMLPFLFSALAMTAVGRAAGAMVEE 518
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 645 VRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIifrmlghatgrpLLGAKVVAAMLMFATVS 724
Cdd:PRK00733  519 VRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIAVGF------------LLGPEALGGLLAGAIVT 586
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2756245149 725 GILMALFLNTAGGAWDNAKKYIETGALGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPIF 798
Cdd:PRK00733  587 GLLLAIFMANAGGAWDNAKKYIEDGNHGGKGSEAHKAAVVGDTVGDPFKDTAGPALNPLIKLMNIVALLIAPLL 660
V_PPase TIGR01104
vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases ...
66-798 0e+00

vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases from eukaryotes (predominantly plants), archaea and bacteria. It is an integral membrane protein and is suggested to have about 15 membrane spanning domains. Proton translocating inorganic pyrophosphatase, like H(+)-ATPase, acidifies the vacuoles and is pivotal to the vacuolar secondary active transport systems in plants. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273444  Cd Length: 695  Bit Score: 597.93  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  66 LFVFCICTLSLFFSLYLTKWVLAKDEGPPEMSEISDAIRDGAEGFFRTQYGTISKMACILAlVILGIYLfrsttpqqeas 145
Cdd:TIGR01104   3 ILIPVCAVIGIAYAVLQWVWVSRVKLGTAKMAEIQQAISEGATAFLFTEYKYVAVFMVAFA-VLIFVFL----------- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 146 GVGRTTSAYITVAsFLLGALCSGIAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSAIVVVGMAVFGVAILYAT 225
Cdd:TIGR01104  71 GSREGFSDFSTVA-FLLGAVTSLLAGYLGMKIATYANARTTLEARKGVGKALIVAFRSGAVMGFLLAGLGLLVLYITILV 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 226 FYVWLEVDSPGSMKVtdlpllLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNV 305
Cdd:TIGR01104 150 FKIYYGDDWEGLFEP------ITGYGFGASSMALFGRVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNV 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 306 GDCAARGADLFESIAAEIISAMILGGTMAqrckIEDPSGFILFplvvhSFDLVISSVGILSIRGTRDSGLISPIEDPMAI 385
Cdd:TIGR01104 224 GDIAGMGADLFESYAESSCAALVLASISS----FGLPHDFTAM-----LYPLALSSVGILVCLLTTLFVKIKPVKEIEPA 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 386 MQKGYSITILLAVVTFGVSTRWLLYT--------EQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSS 457
Cdd:TIGR01104 295 LKKQLIISTVLMTVGVAVISWVALPTgftifnfgTQKEVSNWQLFLCVAVGLWAGLLIGFVTEYYTSNAYSPVQDVADSC 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 458 STGHGTNIIAGVSLGLESTALPVLVISVAIISAFWLghtsglvdesgnptGGLFGTAVATMGMLSTAAYVLTMDMFGPIA 537
Cdd:TIGR01104 375 RTGAATNVIFGLALGYKSVIIPIFAIAASIIVSFSF--------------AGMYGIAMAALGMLSTAGTGLAIDAYGPIS 440
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 538 DNAGGIVEMSQQPESVREITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAafaqlpFKEVDIAIPEVFVGGL 617
Cdd:TIGR01104 441 DNAGGIAEMAGLPHRVRERTDALDAVGNTTAAIGKGFAIGSAALVALALFGAFVSRAV------ITTVDVLTPKVFIGLF 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 618 LGSMLIFLFSAWACSAVGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIF 697
Cdd:TIGR01104 515 VGAMLPYWFSSMTMKSVGRAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGLLVMLTPLIVGFLF 594
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 698 rmlghatgrpllGAKVVAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGA-----LGGKGSESHKAAVTGDTVGDPF 772
Cdd:TIGR01104 595 ------------GVETLSGVLAGVLVSGVQIAISASNTGGAWDNAKKYIEAGSeharsLGPKGSEAHKAAVIGDTVGDPL 662
                         730       740
                  ....*....|....*....|....*.
gi 2756245149 773 KDTAGPSIHVLIKMLATITLVMAPIF 798
Cdd:TIGR01104 663 KDTSGPSLNILIKLMAVESLVFAPFF 688
PLN02255 PLN02255
H(+) -translocating inorganic pyrophosphatase
97-798 1.22e-156

H(+) -translocating inorganic pyrophosphatase


Pssm-ID: 215143  Cd Length: 765  Bit Score: 475.10  E-value: 1.22e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149  97 SEISDAIRDGAEGFFRTQYGTISKMACILALVI---LGIYLFRSTTPQQEASGVGRT-----TSAYITVASFLLGALCSG 168
Cdd:PLN02255   74 AEIQNAISEGATSFLFTEYKYVGIFMVIFAAVIfvfLGSVEGFSTKSQPCTYDKGKLckpalANAAFSTVAFLLGALTSV 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 169 IAGFVGMWVSVRANVRVSSAARRSAREALQIAVRAGgfsAIVVVGMAVFGVAILYAT---FYVWLEVDSPGsmkvtdLPL 245
Cdd:PLN02255  154 VSGFLGMKIATYANARTTLEARKGVGKAFITAFRSG---AVMGFLLAANGLLVLYIAinlFKLYYGDDWEG------LYE 224
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 246 LLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 325
Cdd:PLN02255  225 AITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGKVERNIPEDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAESSCA 304
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 326 AMILGGTmaqrckiedpSGF-ILFPLVVHSFDLVISSVGILSIRGT----RDSGLISPIEDPMAIMQKGYSI-TILLAVV 399
Cdd:PLN02255  305 ALVVASI----------SSFgINHDFTAMCYPLLISSVGIIVCLITtlfaTDFFEIKAVKEIEPALKKQLIIsTVLMTVG 374
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 400 TFGVSTRWLLYT-------EQAPSAWLNFALCGLVGIITAYAFVWISKYYTDYKHEPVRLLALSSSTGHGTNIIAGVSLG 472
Cdd:PLN02255  375 IAVVSWLALPSSftifnfgTQKVVKNWQLFFCVAIGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALG 454
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 473 LESTALPVLVISVAIISAFWLghtsglvdesgnptGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPES 552
Cdd:PLN02255  455 YKSVIIPIFAIAVSIYVSFSL--------------AAMYGIAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHR 520
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 553 VREITDILDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVAafaqlpFKEVDIAIPEVFVGGLLGSMLIFLFSAWACS 632
Cdd:PLN02255  521 IRERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFVSRAG------ISTVDVLTPKVFIGLIVGAMLPYWFSAMTMK 594
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 633 AVGRTAQEVVNEVRRQFIERPGIMDYNEKPDYGRCVAIVASASLREMIRPGALAIISPMAVGIIFrmlghatgrpllGAK 712
Cdd:PLN02255  595 SVGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGALVMLTPLIVGTLF------------GVE 662
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2756245149 713 VVAAMLMFATVSGILMALFLNTAGGAWDNAKKYIETGA------LGGKGSESHKAAVTGDTVGDPFKDTAGPSIHVLIKM 786
Cdd:PLN02255  663 TLSGVLAGALVSGVQIAISASNTGGAWDNAKKYIEAGAseharsLGPKGSDPHKAAVIGDTIGDPLKDTSGPSLNILIKL 742
                         730
                  ....*....|..
gi 2756245149 787 LATITLVMAPIF 798
Cdd:PLN02255  743 MAVESLVFAPFF 754
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH