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Conserved domains on  [gi|159341081|ref|YP_001542640|]
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glycosyltransferase [Acidianus rod-shaped virus 1]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA01633 PHA01633
putative glycosyl transferase group 1
 1-335 0e+00

putative glycosyl transferase group 1


:

Pssm-ID: 107050 [Multi-domain]  Cd Length: 335  Bit Score: 645.50  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081   1 MKTLVLTMNYSSIRNVAEDISETI---GNAVVDITPELYINTTqhfERLIVFVPFIPPMLNNYLLVYNMFKGPKYFYTTA 77
Cdd:PHA01633   1 MKTAILTMNYSSISNVSEDIAEVLrenGEIVTITKNPFYIPKA---EKLIVFIPFHPPSLNPYLYAYYQFKGKKYFYTTC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  78 DGVPSTDIINRHLLRDVTFIPNSNFTAENLSTAGLSVDIPVFHGINFKIVEKAKSLVPKLKQKLDNDFPDTIKFGVVTGM 157
Cdd:PHA01633  78 DGIPNIEIVNKYLLQDVKFIPNSKFSAENLQEVGLQVDLPVFHGINFKIVENAEKLVPQLKQKLDKDFPDTIKFGIVSGL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 158 TKRKNIDLFVQTTKLLNEKFPDPAKRIHFFVISHEDFKKLEVPANVHFVAAFGHQPRENVLAFYGAMDFTFMPTGCEGFG 237
Cdd:PHA01633 158 TKRKNMDLMLQVFNELNTKYPDIAKKIHFFVISHKQFTQLEVPANVHFVAEFGHNSREYIFAFYGAMDFTIVPSGTEGFG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 238 LPLLESMAMGTPVIHQAIPPLTEFTSWQWNYLFRYNTVENYADKDHAQSWKIYRFQPEDAAAAILTAFLSQDREERSMHL 317
Cdd:PHA01633 238 MPVLESMAMGTPVIHQLMPPLDEFTSWQWNLLIKSSKVEEYYDKEHGQKWKIHKFQIEDMANAIILAFELQDREERSMKL 317

                        330
                 ....*....|....*...
gi 159341081 318 MELAKKYDVSFLYKRFLE 335
Cdd:PHA01633 318 KELAKKYDIRNLYTRFLE 335
 
Name Accession Description Interval E-value
PHA01633 PHA01633
putative glycosyl transferase group 1
 1-335 0e+00

putative glycosyl transferase group 1


Pssm-ID: 107050 [Multi-domain]  Cd Length: 335  Bit Score: 645.50  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081   1 MKTLVLTMNYSSIRNVAEDISETI---GNAVVDITPELYINTTqhfERLIVFVPFIPPMLNNYLLVYNMFKGPKYFYTTA 77
Cdd:PHA01633   1 MKTAILTMNYSSISNVSEDIAEVLrenGEIVTITKNPFYIPKA---EKLIVFIPFHPPSLNPYLYAYYQFKGKKYFYTTC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  78 DGVPSTDIINRHLLRDVTFIPNSNFTAENLSTAGLSVDIPVFHGINFKIVEKAKSLVPKLKQKLDNDFPDTIKFGVVTGM 157
Cdd:PHA01633  78 DGIPNIEIVNKYLLQDVKFIPNSKFSAENLQEVGLQVDLPVFHGINFKIVENAEKLVPQLKQKLDKDFPDTIKFGIVSGL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 158 TKRKNIDLFVQTTKLLNEKFPDPAKRIHFFVISHEDFKKLEVPANVHFVAAFGHQPRENVLAFYGAMDFTFMPTGCEGFG 237
Cdd:PHA01633 158 TKRKNMDLMLQVFNELNTKYPDIAKKIHFFVISHKQFTQLEVPANVHFVAEFGHNSREYIFAFYGAMDFTIVPSGTEGFG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 238 LPLLESMAMGTPVIHQAIPPLTEFTSWQWNYLFRYNTVENYADKDHAQSWKIYRFQPEDAAAAILTAFLSQDREERSMHL 317
Cdd:PHA01633 238 MPVLESMAMGTPVIHQLMPPLDEFTSWQWNLLIKSSKVEEYYDKEHGQKWKIHKFQIEDMANAIILAFELQDREERSMKL 317

                        330
                 ....*....|....*...
gi 159341081 318 MELAKKYDVSFLYKRFLE 335
Cdd:PHA01633 318 KELAKKYDIRNLYTRFLE 335
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 96-251 2.52e-17

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 81.82  E-value: 2.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  96 FIPNSNFTAENLSTAGLSVDIPVFH---GINFKivekakSLVPKLKQKLdNDFPDTIKFGVVTGMTKRKNIDLFVQTTKL 172
Cdd:cd03801  144 VIAVSEALRDELRALGGIPPEKIVVipnGVDLE------RFSPPLRRKL-GIPPDRPVLLFVGRLSPRKGVDLLLEALAK 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 173 LNEKFPDpakrIHFFVISHED-------FKKLEVPANVHFVaafGHQPRENVLAFYGAMDFTFMPTGCEGFGLPLLESMA 245
Cdd:cd03801  217 LLRRGPD----VRLVIVGGDGplraeleELELGLGDRVRFL---GFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMA 289


                 ....*.
gi 159341081 246 MGTPVI 251
Cdd:cd03801  290 AGLPVV 295
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 157-281 1.41e-14

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 70.38  E-value: 1.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  157 MTKRKNIDLFVQTTKLLNEKFPDpakrIHFFVISHEDFKK--------LEVPANVHFvaaFGHQPRENVLAFYGAMDFTF 228
Cdd:pfam00534  11 LEPEKGLDLLIKAFALLKEKNPN----LKLVIAGDGEEEKrlkklaekLGLGDNVIF---LGFVSDEDLPELLKIADVFV 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 159341081  229 MPTGCEGFGLPLLESMAMGTPVIHQAIPPLTE-FTSWQWNYLFRYNTVENYADK 281
Cdd:pfam00534  84 LPSRYEGFGIVLLEAMACGLPVIASDVGGPPEvVKDGETGFLVKPNNAEALAEA 137
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 219-281 1.09e-08

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 52.69  E-value: 1.09e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 159341081 219 AFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVIHQAIPPLTEF-TSWQWNYLFRYNTVENYADK 281
Cdd:COG0438   16 ALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEViEDGETGLLVPPGDPEALAEA 79
 
Name Accession Description Interval E-value
PHA01633 PHA01633
putative glycosyl transferase group 1
 1-335 0e+00

putative glycosyl transferase group 1


Pssm-ID: 107050 [Multi-domain]  Cd Length: 335  Bit Score: 645.50  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081   1 MKTLVLTMNYSSIRNVAEDISETI---GNAVVDITPELYINTTqhfERLIVFVPFIPPMLNNYLLVYNMFKGPKYFYTTA 77
Cdd:PHA01633   1 MKTAILTMNYSSISNVSEDIAEVLrenGEIVTITKNPFYIPKA---EKLIVFIPFHPPSLNPYLYAYYQFKGKKYFYTTC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  78 DGVPSTDIINRHLLRDVTFIPNSNFTAENLSTAGLSVDIPVFHGINFKIVEKAKSLVPKLKQKLDNDFPDTIKFGVVTGM 157
Cdd:PHA01633  78 DGIPNIEIVNKYLLQDVKFIPNSKFSAENLQEVGLQVDLPVFHGINFKIVENAEKLVPQLKQKLDKDFPDTIKFGIVSGL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 158 TKRKNIDLFVQTTKLLNEKFPDPAKRIHFFVISHEDFKKLEVPANVHFVAAFGHQPRENVLAFYGAMDFTFMPTGCEGFG 237
Cdd:PHA01633 158 TKRKNMDLMLQVFNELNTKYPDIAKKIHFFVISHKQFTQLEVPANVHFVAEFGHNSREYIFAFYGAMDFTIVPSGTEGFG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 238 LPLLESMAMGTPVIHQAIPPLTEFTSWQWNYLFRYNTVENYADKDHAQSWKIYRFQPEDAAAAILTAFLSQDREERSMHL 317
Cdd:PHA01633 238 MPVLESMAMGTPVIHQLMPPLDEFTSWQWNLLIKSSKVEEYYDKEHGQKWKIHKFQIEDMANAIILAFELQDREERSMKL 317

                        330
                 ....*....|....*...
gi 159341081 318 MELAKKYDVSFLYKRFLE 335
Cdd:PHA01633 318 KELAKKYDIRNLYTRFLE 335
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 96-251 2.52e-17

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 81.82  E-value: 2.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  96 FIPNSNFTAENLSTAGLSVDIPVFH---GINFKivekakSLVPKLKQKLdNDFPDTIKFGVVTGMTKRKNIDLFVQTTKL 172
Cdd:cd03801  144 VIAVSEALRDELRALGGIPPEKIVVipnGVDLE------RFSPPLRRKL-GIPPDRPVLLFVGRLSPRKGVDLLLEALAK 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 173 LNEKFPDpakrIHFFVISHED-------FKKLEVPANVHFVaafGHQPRENVLAFYGAMDFTFMPTGCEGFGLPLLESMA 245
Cdd:cd03801  217 LLRRGPD----VRLVIVGGDGplraeleELELGLGDRVRFL---GFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMA 289


                 ....*.
gi 159341081 246 MGTPVI 251
Cdd:cd03801  290 AGLPVV 295
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 157-281 1.41e-14

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 70.38  E-value: 1.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  157 MTKRKNIDLFVQTTKLLNEKFPDpakrIHFFVISHEDFKK--------LEVPANVHFvaaFGHQPRENVLAFYGAMDFTF 228
Cdd:pfam00534  11 LEPEKGLDLLIKAFALLKEKNPN----LKLVIAGDGEEEKrlkklaekLGLGDNVIF---LGFVSDEDLPELLKIADVFV 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 159341081  229 MPTGCEGFGLPLLESMAMGTPVIHQAIPPLTE-FTSWQWNYLFRYNTVENYADK 281
Cdd:pfam00534  84 LPSRYEGFGIVLLEAMACGLPVIASDVGGPPEvVKDGETGFLVKPNNAEALAEA 137
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 99-325 4.35e-14

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 72.40  E-value: 4.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  99 NSNFTAENLST---AGLSVDIPVFHGINFKIVEKAKSLVPKLKQKLDNDFpdtikFGVVTGMTKRKNIDLFVQTTKLLNE 175
Cdd:cd03809  145 VSEATRDDIIKfygVPPEKIVVIPLGVDPSFFPPESAAVLIAKYLLPEPY-----FLYVGTLEPRKNHERLLKAFALLKK 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 176 KFPDpakriHFFVIS----------HEDFKKLEVPANVHFvaaFGHQPRENVLAFYGAMDFTFMPTGCEGFGLPLLESMA 245
Cdd:cd03809  220 QGGD-----LKLVIVggkgwedeelLDLVKKLGLGGRVRF---LGYVSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMA 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 246 MGTPVIHQAIPPLTEFTSwqwnylfryntvenyadkDHAqswkiYRFQPEDA---AAAILTAFLSQD-REERSMHLMELA 321
Cdd:cd03809  292 CGTPVIASNISVLPEVAG------------------DAA-----LYFDPLDPesiADAILRLLEDPSlREELIRKGLERA 348


                 ....
gi 159341081 322 KKYD 325
Cdd:cd03809  349 KKFS 352
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 100-321 6.10e-12

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 65.84  E-value: 6.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 100 SNFTAENLsTAGLSVD------IPvfHGINFKIVEKAKSLVPKLKQKLDNDFPdtiKFGVVTGMTKRKNIDLFVQTTKLL 173
Cdd:cd03819  134 SELVRDHL-IEALGVDperirvIP--NGVDTDRFPPEAEAEERAQLGLPEGKP---VVGYVGRLSPEKGWLLLVDAAAEL 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 174 nekfpDPAKRIHFFVI-----SHEDFKKLEVPANVHFVAAFGHqpRENVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGT 248
Cdd:cd03819  208 -----KDEPDFRLLVAgdgpeRDEIRRLVERLGLRDRVTFTGF--REDVPAALAASDVVVLPSLHEEFGRVALEAMACGT 280

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 159341081 249 PVIHQAIPPLTEftswqwnylfrynTVENyadkdHAQSWKIYRFQPEDAAAAILTAFLS-QDREERSMHLMELA 321
Cdd:cd03819  281 PVVATDVGGARE-------------IVVH-----GRTGLLVPPGDAEALADAIRAAKLLpEAREKLQAAAALTE 336
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
159-281 3.06e-11

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 60.22  E-value: 3.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  159 KRKNIDLFVQTTKLLNEKFPDpakrIHFFVISHEDFKKLE-----VPANVHFVaafGHqpRENVLAFYGAMDFTFMPTGC 233
Cdd:pfam13692  13 NVKGVDYLLEAVPLLRKRDND----VRLVIVGDGPEEELEelaagLEDRVIFT---GF--VEDLAELLAAADVFVLPSLY 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 159341081  234 EGFGLPLLESMAMGTPVIHQAIPPLTEFTSWQWNYLFRYNTVENYADK 281
Cdd:pfam13692  84 EGFGLKLLEAMAAGLPVVATDVGGIPELVDGENGLLVPPGDPEALAEA 131
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 146-251 7.28e-11

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 62.78  E-value: 7.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 146 PDTIKFGVVTGMTKRKNIDLFVQTTKLLNEKFPDpakrIHFFVISH-EDFKKLE-------VPANVHFVaafGHQPRENV 217
Cdd:cd03798  198 LDAFVILFVGRLIPRKGIDLLLEAFARLAKARPD----VVLLIVGDgPLREALRalaedlgLGDRVTFT---GRLPHEQV 270

                         90       100       110
                 ....*....|....*....|....*....|....
gi 159341081 218 LAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03798  271 PAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVV 304
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 122-251 1.79e-10

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 61.46  E-value: 1.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 122 INFKIVEKAKSLV-------PKLKQKLDNDFP-DTIKFGVVTGMTKRKNIDLFVQTTKLLNEKFPDpakrIHFFVI---- 189
Cdd:cd03808  155 IKKGIIKKKKTVLipgsgvdLDRFQYSPESLPsEKVVFLFVARLLKDKGIDELIEAAKILKKKGPN----VRFLLVgdge 230

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 159341081 190 ----SHEDFKKLEVPANVHFVaafGHqpRENVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03808  231 lenpSEILIEKLGLEGRIEFL---GF--RSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVI 291
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 95-251 2.10e-10

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 61.19  E-value: 2.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  95 TFIPNSNFTAENLSTAGLSVdipvfhginfKIVEKAKSLVPKLKQKLDNDFPDT--IKFGVVTGMTKRKNIDLFVQTTKL 172
Cdd:cd03823  146 AVLAPSRFTANLHEANGLFS----------ARISVIPNAVEPDLAPPPRRRPGTerLRFGYIGRLTEEKGIDLLVEAFKR 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 173 LnekfpdPAKRIHFFVISHEDFKKLEVPANVHFVAAFGHQPRENVLAFYGAMDFTFMPTGC-EGFGLPLLESMAMGTPVI 251
Cdd:cd03823  216 L------PREDIELVIAGHGPLSDERQIEGGRRIAFLGRVPTDDIKDFYEKIDVLVVPSIWpEPFGLVVREAIAAGLPVI 289
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 147-251 2.55e-10

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 60.79  E-value: 2.55e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 147 DTIKFGVVTGMTKRKNIDLFVQTTKLLNEKFPDpakrIHFFVISHEDFKK--------LEVPANVHFvaaFGHqpRENVL 218
Cdd:cd03807  189 DRRVIGIVGRLHPVKDHSDLLRAAALLVETHPD----LRLLLVGRGPERPnlerllleLGLEDRVHL---LGE--RSDVP 259

                         90       100       110
                 ....*....|....*....|....*....|...
gi 159341081 219 AFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03807  260 ALLPAMDIFVLSSRTEGFPNALLEAMACGLPVV 292
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 99-251 4.79e-10

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 60.06  E-value: 4.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  99 NSNFTAENLSTAGLSV--DIPVFHgiNFKIVEKAKslvPKLKQKLDNDFPDTIKFGVVTGMTKRKNIDLFVQTTKLLNEK 176
Cdd:cd03811  142 VSKGIKEDLIRLGPSPpeKIEVIY--NPIDIDRIR---ALAKEPILNEPEDGPVILAVGRLDPQKGHDLLIEAFAKLRKK 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 177 FPDpakrIHFFVI-SHEDFKKLE-------VPANVHFVaafGHQPreNVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGT 248
Cdd:cd03811  217 YPD----VKLVILgDGPLREELEklakelgLAERVIFL---GFQS--NPYPYLKKADLFVLSSRYEGFPNVLLEAMALGT 287


                 ...
gi 159341081 249 PVI 251
Cdd:cd03811  288 PVV 290
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 153-251 1.38e-09

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 57.80  E-value: 1.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 153 VVTGMTKRKNIDLFVQTTKLLNEKFPDpakRIHFFVISHEDFKKLEVPA-------NVHFVaaFGHQPRENVLAFYGAMD 225
Cdd:cd01635  115 SVGRLVPEKGIDLLLEALALLKARLPD---LVLVLVGGGGEREEEEALAaalglleRVVII--GGLVDDEVLELLLAAAD 189

                         90       100
                 ....*....|....*....|....*.
gi 159341081 226 FTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd01635  190 VFVLPSRSEGFGLVLLEAMAAGKPVI 215
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 219-281 1.09e-08

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 52.69  E-value: 1.09e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 159341081 219 AFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVIHQAIPPLTEF-TSWQWNYLFRYNTVENYADK 281
Cdd:COG0438   16 ALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEViEDGETGLLVPPGDPEALAEA 79
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 92-251 2.03e-08

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 55.03  E-value: 2.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  92 RDVTFIPNSNFTAENLSTAGLSVDIPVFH---GIN---FKIVEKAKSlvpKLKQKLDNDFPdTIKFGVVTGMTKRKNIDL 165
Cdd:cd03825  137 KRLTIVAPSRWLADMVRRSPLLKGLPVVVipnGIDteiFAPVDKAKA---RKRLGIPQDKK-VILFGAESVTKPRKGFDE 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 166 FVQTTKLLNEKfpdpaKRIHFFVISHEDFKKLEVPANVHfvaAFGHQPRENVLA-FYGAMDFTFMPTGCEGFGLPLLESM 244
Cdd:cd03825  213 LIEALKLLATK-----DDLLLVVFGKNDPQIVILPFDII---SLGYIDDDEQLVdIYSAADLFVHPSLADNLPNTLLEAM 284


                 ....*..
gi 159341081 245 AMGTPVI 251
Cdd:cd03825  285 ACGTPVV 291
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 57-251 3.50e-08

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 54.21  E-value: 3.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  57 LNNYLLVYNMFKGPKYFYTTADGV--PSTDI----INRHLLRDVTFIPNsnftaenlstaglsvdipvfhGINFKIVEKA 130
Cdd:cd03817  128 KGKLLVKAVVRKLVRRFYNHTDAViaPSEKIkdtlREYGVKGPIEVIPN---------------------GIDLDKFEKP 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 131 KSLVPKLKQKLDNDFPdtiKFGVVTGMTKRKNIDLFVQTTKLLNEKFPdpakrIHFFVISH----EDFKKL----EVPAN 202
Cdd:cd03817  187 LNTEERRKLGLPPDEP---ILLYVGRLAKEKNIDFLLRAFAELKKEPN-----IKLVIVGDgperEELKELarelGLADK 258

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 159341081 203 VHFvaaFGHQPRENVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03817  259 VIF---TGFVPREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVV 304
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 147-251 3.68e-05

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 44.97  E-value: 3.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 147 DTIKFGVVTGMTKRKN----IDLFvqttkllnEKFPDPAKRIHFFVISHEDF--------KKLEVPANVHFVaafGHqpR 214
Cdd:cd03812  190 DKLVLGHVGRFNEQKNhsflIDIF--------EELKKKNPNVKLVLVGEGELkekikekvKELGLEDKVIFL---GF--R 256

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 159341081 215 ENVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03812  257 NDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCL 293
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 28-251 3.99e-05

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 45.03  E-value: 3.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  28 VVDITPELYINTtqhferlivfvpfipPMLNNYLLVYNMFKGPKYFYTTADGV-PSTDIINRHLLRD------VTFIPNs 100
Cdd:cd03794  130 VRDLWPESLIAL---------------GVLKKGSLLKLLKKLERKLYRLADAIiVLSPGLKEYLLRKgvpkekIIVIPN- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 101 nftaenlstaglsvdipvfhGINFKIVEKAKSLVPKLKQKLDNDFpdtiKFGVVTGMTKRKNIDLFVQTTKLLNEKfpdp 180
Cdd:cd03794  194 --------------------WADLEEFKPPPKDELRKKLGLDDKF----VVVYAGNIGKAQGLETLLEAAERLKRR---- 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 181 aKRIHFFVI----SHEDFKKL---EVPANVHFvaaFGHQPRENVLAFYGAMDFTFMP---TGCEGFGLP--LLESMAMGT 248
Cdd:cd03794  246 -PDIRFLFVgdgdEKERLKELakaRGLDNVTF---LGRVPKEEVPELLSAADVGLVPlkdNPANRGSSPskLFEYMAAGK 321


                 ...
gi 159341081 249 PVI 251
Cdd:cd03794  322 PIL 324
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 194-251 5.96e-05

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 44.20  E-value: 5.96e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 159341081 194 FKKLEVPA---NVHFVAAFGHQPRENVLAFYGAMdfTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03802  210 FYYLQEPLpgpRIEFIGEVGHDEKQELLGGARAL--LFPINWDEPFGLVMIEAMACGTPVI 268
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 83-318 1.56e-04

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 43.13  E-value: 1.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  83 TDIINRHLLRDVTFIPNSNFTAENLSTAGLSVDIPVF-HGINFKIVEKAKSLVPKLkqkldNDFPDTIKFGVVTGMTKRK 161
Cdd:cd03821  143 HLIERRNLNNAALVHFTSEQEADELRRFGLEPPIAVIpNGVDIPEFDPGLRDRRKH-----NGLEDRRIILFLGRIHPKK 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 162 NIDLFVQTTKLLNEKFPDpakriHFFVISHEDfkKLEVPANVHFVAAFGHQPR---------ENVLAFYGAMDFTFMPTG 232
Cdd:cd03821  218 GLDLLIRAARKLAEQGRD-----WHLVIAGPD--DGAYPAFLQLQSSLGLGDRvtftgplygEAKWALYASADLFVLPSY 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 233 CEGFGLPLLESMAMGTPVIhqaippLTEFTSWqWNYLfryntvenyadkDHAQSWKIYrfqPEDAA-AAILTAFLSQDRE 311
Cdd:cd03821  291 SENFGNVVAEALACGLPVV------ITDKCGL-SELV------------EAGCGVVVD---PNVSSlAEALAEALRDPAD 348


                 ....*..
gi 159341081 312 ERSMHLM 318
Cdd:cd03821  349 RKRLGEM 355
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 62-251 2.64e-04

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 42.28  E-value: 2.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081  62 LVYNMFKGPKYFYTTADG--VPSTDIIN---RHLLRDVTFIPnsnftaenlstagLSVDIPVFHginfkivekakslvPK 136
Cdd:cd03814  131 LSWLAWAYLRWFHNPFDTtlVPSPSIAReleGHGFERVRLWP-------------RGVDTELFH--------------PS 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 137 LKQKLDND---FPDTIKFGVVTGMTKRKNIDLFVQTTKLLNEKFPdpakrIHFFVI-SHEDFKKLE-VPANVHFVaafGH 211
Cdd:cd03814  184 RRDAALRRrlgPPGRPLLLYVGRLAPEKNLEALLDADLPLAASPP-----VRLVVVgDGPARAELEaRGPDVIFT---GF 255

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 159341081 212 QPRENVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03814  256 LTGEELARAYASADVFVFPSRTETFGLVVLEAMASGLPVV 295
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 195-251 3.89e-04

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 41.95  E-value: 3.89e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 159341081 195 KKLEVPANVHFvaaFGHQPRenVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd04962  246 RELGVEDRVLF---LGKQDD--VEELLSIADLFLLPSEKESFGLAALEAMACGVPVV 297
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 209-251 1.05e-03

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 40.69  E-value: 1.05e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 159341081 209 FGHQPRENVLAFYGAMDFTFMPTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03800  288 PGRVSRDDLPELYRAADVFVVPSLYEPFGLTAIEAMACGTPVV 330
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 157-251 1.76e-03

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 39.91  E-value: 1.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 157 MTKRKNIDLFVQTTKLLNEKFPDPAKRIhffVISHEDFKKLEvpanvHFVAAFGHQ-------PRENVLAFYGAMDFTFM 229
Cdd:cd03820  190 LTYQKGFDLLIEAWALIAKKHPDWKLRI---YGDGPEREELE-----KLIDKLGLEdrvkllgPTKNIAEEYANSSIFVL 261

                         90       100
                 ....*....|....*....|..
gi 159341081 230 PTGCEGFGLPLLESMAMGTPVI 251
Cdd:cd03820  262 SSRYEGFPMVLLEAMAYGLPII 283
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 161-251 4.65e-03

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 38.42  E-value: 4.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 159341081 161 KNIDLFVqttkllnEKFPDPAKRIhfFVISH-EDFKKLEVPA--NVHFVaafGHQPRENVLAFYG-AMDFTFMptGCEGF 236
Cdd:cd03804  212 KRIDLAV-------EAFNELPKRL--VVIGDgPDLDRLRAMAspNVEFL---GYQPDEVLKELLSkARAFVFA--AEEDF 277

                         90
                 ....*....|....*
gi 159341081 237 GLPLLESMAMGTPVI 251
Cdd:cd03804  278 GIVPVEAQACGTPVI 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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