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Conserved domains on  [gi|299829101|ref|YP_003735116|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Hydrolagus lemures]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.01e-64

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.97  E-value: 3.01e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNMMNWSGVDEFSSLSLWRGDMIGASLMYSSGVFLLVLVGWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 299829101 161 LIRGLSRGALRVV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.01e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.97  E-value: 3.01e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNMMNWSGVDEFSSLSLWRGDMIGASLMYSSGVFLLVLVGWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 299829101 161 LIRGLSRGALRVV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-137 8.26e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 48.65  E-value: 8.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   17 VAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPESWWDWSVMANVSVYVL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 299829101   97 GVSVAALYFCGGWNMMNWSGVDEFSSLSLwrgDMIGASLMY 137
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNI---EAIGELLFT 118
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.01e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.97  E-value: 3.01e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNMMNWSGVDEFSSLSLWRGDMIGASLMYSSGVFLLVLVGWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 299829101 161 LIRGLSRGALRVV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.56e-43

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 142.29  E-value: 1.56e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNMMNWSGVDEFSSlSLWRGDMIGASLMYSSGVFLLVLVGWVLLLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEF-SVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 299829101 161 LIRGLSRGALRVV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 2.97e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 123.71  E-value: 2.97e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNM-MNWSGVDEFSSLSLWRGDMIGASLMYSSGVFLLVLVGWVLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMeGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 299829101 160 ELIRGLSRGALRVV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 3.19e-33

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 115.86  E-value: 3.19e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNMMNWSGVDEFSSLSlwrgdMIGASLMYSSGVFLLVLVGWVLLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLD-----LSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 299829101 161 LIRGLSRGALRVV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-140 7.03e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 89.48  E-value: 7.03e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   1 MIYFVILMLMCFIMGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 299829101  81 SWWDWSVMANVSVYVLGVSVAALYFCGGWNMMNWsgVDEFSSLSLW-----------RGDMIGASLMYSSG 140
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEV--VFNFNGLGDWviydtggsgffSEDAMGVAALYSYG 150
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-79 3.39e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 66.47  E-value: 3.39e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 299829101   1 MIYFVILMLMCFimGLVAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHP 79
Cdd:MTH00045   1 MVFYLFLILMLF--GSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-137 8.26e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 48.65  E-value: 8.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299829101   17 VAVASNPAPYFAAFGLVVSAAVGCGLLASHGVSFLSLVLFLIYLGGMLVVFVYSAALTADPHPESWWDWSVMANVSVYVL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 299829101   97 GVSVAALYFCGGWNMMNWSGVDEFSSLSLwrgDMIGASLMY 137
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNI---EAIGELLFT 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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