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Conserved domains on  [gi|304322857|ref|YP_003856699|]
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ATP synthase F0 subunit 6 (mitochondrion) [Mekongiella xizangensis]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009593)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-225 1.84e-78

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 214441  Cd Length: 223  Bit Score: 234.68  E-value: 1.84e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTSLlNLPINWSSTFIGLLLIPTMYWLMPLWILLMWNKRNLNFHNEFKTLIGPKsFNGTTFMFISMLIM 80
Cdd:MTH00157   1 MMTNLFSIFDPSTSF-NLSLNWLSTFLGLLFIPSSFWLIPSRYNILWNKILKTLHKEFKTLLGPK-NKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  81 MMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTLAI 160
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 304322857 161 RLVANMIAGYLLLTLLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSETY 225
Cdd:MTH00157 159 RLAANMIAGHLLLTLLGNTGPSLSSMILSILILIQILLLILESAVAIIQSYVFSVLSTLYSSEVN 223
 
Name Accession Description Interval E-value
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-225 1.84e-78

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 234.68  E-value: 1.84e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTSLlNLPINWSSTFIGLLLIPTMYWLMPLWILLMWNKRNLNFHNEFKTLIGPKsFNGTTFMFISMLIM 80
Cdd:MTH00157   1 MMTNLFSIFDPSTSF-NLSLNWLSTFLGLLFIPSSFWLIPSRYNILWNKILKTLHKEFKTLLGPK-NKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  81 MMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTLAI 160
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 304322857 161 RLVANMIAGYLLLTLLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSETY 225
Cdd:MTH00157 159 RLAANMIAGHLLLTLLGNTGPSLSSMILSILILIQILLLILESAVAIIQSYVFSVLSTLYSSEVN 223
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 5-223 1.86e-31

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 114.61  E-value: 1.86e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857    5 LFSTFDPST-SLLNLPINWSSTFIGLLLIPTMYWLMPLWI----LLMWNKRNLNFHNEFKTLIGPKSFNgTTFMFISMLI 79
Cdd:TIGR01131   1 LFSQFDISPiTLFSLTLLSLILLLSLLIFLISSSLSRWLIpsrwQNLMESIYEFVLSIVKSQIGGKKGK-FFPLIFTLFL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   80 MMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTLA 159
Cdd:TIGR01131  80 FILISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLS 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 304322857  160 IRLVANMIAGYLLLTLL-GNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSE 223
Cdd:TIGR01131 160 VRLFANISAGHLLLTLLsGLLFSLMSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYLND 224
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 73-222 2.19e-29

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 107.10  E-value: 2.19e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  73 MFISMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNT 152
Cdd:cd00310    7 LLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISEL 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 153 IWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSS 222
Cdd:cd00310   87 IRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLLLPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP-synt_A pfam00119
ATP synthase A chain;
54-222 1.95e-16

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 74.83  E-value: 1.95e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   54 FHNEFKTLIGPKSFNGTTFMFISMLIMMMFNNFMGLL---PYIFTKSSDMTLTFSIAMPMWLSFMQFG-WINNTKHMLAH 129
Cdd:pfam00119  41 VDNIVKDNIGKKKGRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGiKKHGLGGYFKK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  130 LVLQGTPTALMSFMVLIETISNTIWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISS---QMLLLTLESAVS 206
Cdd:pfam00119 121 LFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLIFALLSAGFLLGVIPpllGVAWTLFELLVA 200

                         170
                  ....*....|....*.
gi 304322857  207 LIQAYVFSILSTLYSS 222
Cdd:pfam00119 201 FIQAYVFTMLTAVYIS 216
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 69-220 5.89e-14

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 67.79  E-value: 5.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  69 GTTFMFIsmlimmMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFG-WINNTKHMLAHLVLQGTPtALMSFMVLIE 147
Cdd:COG0356   62 LTLFLFI------LVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGiKKKGLGGYLKHLFFPPFP-WLAPLMLPIE 134

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 304322857 148 TISNTIWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISsqMLLLTLESAVSLIQAYVFSILSTLY 220
Cdd:COG0356  135 IISELARPLSLSLRLFGNMFAGHIILLLLAGLAPFLLLGVLSLLLP--VAWTAFELLVGFLQAYIFTMLTAVY 205
 
Name Accession Description Interval E-value
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-225 1.84e-78

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 234.68  E-value: 1.84e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTSLlNLPINWSSTFIGLLLIPTMYWLMPLWILLMWNKRNLNFHNEFKTLIGPKsFNGTTFMFISMLIM 80
Cdd:MTH00157   1 MMTNLFSIFDPSTSF-NLSLNWLSTFLGLLFIPSSFWLIPSRYNILWNKILKTLHKEFKTLLGPK-NKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  81 MMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTLAI 160
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 304322857 161 RLVANMIAGYLLLTLLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSETY 225
Cdd:MTH00157 159 RLAANMIAGHLLLTLLGNTGPSLSSMILSILILIQILLLILESAVAIIQSYVFSVLSTLYSSEVN 223
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-225 7.60e-37

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 128.61  E-value: 7.60e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTSLLNLPI--NWSSTFIGLLLIPTMYWLMPLWILLMWNKRNlNFHNEFKTLIGPKSFNGTTFMFISML 78
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMIslSWITLLLFLLLMPSSVWFCPSKLQVFMLMFS-TFLPEMILRSNGSYILGSASIIISLF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  79 IMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTL 158
Cdd:MTH00176  80 ILVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 159 AIRLVANMIAGYLLLT---LLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSETY 225
Cdd:MTH00176 160 AVRLAANLSAGHLLLGllgAAMWGLLPVSPLIGFLLLIVQILYFMFEIAVCMIQAYVFTLLLSLYLDEHP 229
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 5-223 1.86e-31

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 114.61  E-value: 1.86e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857    5 LFSTFDPST-SLLNLPINWSSTFIGLLLIPTMYWLMPLWI----LLMWNKRNLNFHNEFKTLIGPKSFNgTTFMFISMLI 79
Cdd:TIGR01131   1 LFSQFDISPiTLFSLTLLSLILLLSLLIFLISSSLSRWLIpsrwQNLMESIYEFVLSIVKSQIGGKKGK-FFPLIFTLFL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   80 MMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTLA 159
Cdd:TIGR01131  80 FILISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLS 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 304322857  160 IRLVANMIAGYLLLTLL-GNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSE 223
Cdd:TIGR01131 160 VRLFANISAGHLLLTLLsGLLFSLMSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYLND 224
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 73-222 2.19e-29

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 107.10  E-value: 2.19e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  73 MFISMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNT 152
Cdd:cd00310    7 LLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISEL 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 153 IWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSS 222
Cdd:cd00310   87 IRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLLLPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 1-223 5.17e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 105.97  E-value: 5.17e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTSLLNL----PINWSSTFIGLLLIPTMYWLMPLWILLMWNKRNLNFHNEFKTLIGpKSFNGTTFMFIS 76
Cdd:MTH00005   1 MLTDIFSSFDPATNSLFNnlssTAFWAFNFSIILLLSSSFWITPNRLSSIMSPPKSTMHTQLSRTFG-KHLKGFSSLISA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  77 MLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPG 156
Cdd:MTH00005  80 LFTMIILMNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPI 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 157 TLAIRLVANMIAGYLLLTLLGNTGNMISFGL---MTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSE 223
Cdd:MTH00005 160 TLSFRLAANMSAGHIVLSLIGIYAASALFSSissTILLILTQMGYILFEVGICLIQAYIFCLLLSLYSDD 229
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-223 4.19e-27

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 103.49  E-value: 4.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDpSTSLLNLPINWSSTFIGLLLIPTMYWLM---PLWILLMWNKRNlnFHNEFKTLIGPKSFNGTtFMFISM 77
Cdd:MTH00179   1 MMLSMFDQFE-SPSLLGIPLLALALLLPWLLFPSLTNRWlnnRLSTLQSWFFGS--FTFQLMQPINKKGHKWA-VLFLSL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  78 LIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGT 157
Cdd:MTH00179  77 MLFLLTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 304322857 158 LAIRLVANMIAGYLLL--TLLGNTGNMISFGLMTILISSQMLLLT-LESAVSLIQAYVFSILSTLYSSE 223
Cdd:MTH00179 157 LGVRLTANITAGHLLMhlISSAVFVLMNFMGMVALLTLLVLFLLTlLEVAVAMIQAYVFVLLLSLYLQE 225
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 3-223 4.28e-26

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 100.82  E-value: 4.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   3 TNLFSTFDPSTsLLNLPINWSSTFIGL---LLIPTMYWLmPLWILLMWNkrnlNFHNEFKTLIGPKSFNGT---TFMFIS 76
Cdd:MTH00035   5 NSIFGQFSPDT-ILFIPLTLLSSVIALswlFFINPTNWL-PSRSQSIWL----TFRQEILKLIFQNTNPNTapwAGLLTT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  77 MLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPG 156
Cdd:MTH00035  79 VFILILSINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPI 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 304322857 157 TLAIRLVANMIAGYLLLTLLGNTGNMI--SFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSE 223
Cdd:MTH00035 159 ALGLRLAANLTAGHLLIFLLSTAIWELsnSPLISIITLIIFFLLFILEIGVACIQAYVFTALVHFYLEQ 227
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 1-224 2.80e-25

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 98.78  E-value: 2.80e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTSLLNLP--INWSSTFIGLLLIPTMYWLMPLWILLMWNKRNLNFHNEFKTLIGpKSFNGTTFMFISML 78
Cdd:MTH00173   1 MMVDLFSSFDDHNSSFSSLsfLMWLLSLMSLFFFSSSVWVSSSNLSSVFKLFVLTVSSQVTRSSG-LNLGGFSLLLSSLF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  79 IMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTL 158
Cdd:MTH00173  80 LFLISLNLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 159 AIRLVANMIAGYLLLT----LLGNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLYSSET 224
Cdd:MTH00173 160 TVRLLANISAGHIVLTlignYLSSSLFSSSVVSLLLVLLIQVGYFIFEVAVMLIQAYIFTLLIKLYSDEH 229
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 73-223 1.85e-23

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 93.78  E-value: 1.85e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  73 MFISMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNT 152
Cdd:MTH00132  72 LLTSLMLFLITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLF 151

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 304322857 153 IWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMT--ILISSQMLLLT-LESAVSLIQAYVFSILSTLYSSE 223
Cdd:MTH00132 152 IRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTvaILTATLLFLLTlLEVAVAMIQAYVFVLLLSLYLQE 225
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-220 3.74e-23

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 93.09  E-value: 3.74e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDPSTsLLNLPINWSSTFIGLLLIPTMYWLMP-------LWILLMWNKRNLNFHNefktligpKSFNGTTFM 73
Cdd:MTH00101   1 MNENLFASFITPT-ILGLPIVTLIIMFPSLLFPTPNRLINnrlisiqQWLIQLTSKQMMTIHN--------TKGQTWSLM 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  74 FISMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTI 153
Cdd:MTH00101  72 LMSLILFIGSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFI 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 154 WPGTLAIRLVANMIAGYLLLTLL---GNTGNMISFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLY 220
Cdd:MTH00101 152 QPMALAVRLTANITAGHLLIHLIggaTLALMSISTTTALITFIILILLTILEFAVALIQAYVFTLLVSLY 221
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-223 1.79e-22

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 91.04  E-value: 1.79e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFDpSTSLLNLPINWSSTFIGLLLIPTM--YWLM-PLWILLMWNkrnlnFHNEFKTLIGPKSFNGT--TFMFI 75
Cdd:MTH00120   1 MNLNFFDQFS-SPELLGIPLILLAMLIPALLIPSPknRLLTnRLTTLQLWL-----IKLITKQLMLPLNKKGHkwALILT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  76 SMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWP 155
Cdd:MTH00120  75 SLMLLLLLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRP 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 304322857 156 GTLAIRLVANMIAGYLL-----LTLLGNTGNMISFGLMTILIssQMLLLTLESAVSLIQAYVFSILSTLYSSE 223
Cdd:MTH00120 155 LALGVRLTANLTAGHLLiqlisTATLNLLPTMPTLSLLTLII--LLLLTILELAVAMIQAYVFVLLLSLYLQE 225
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-223 5.70e-22

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 90.03  E-value: 5.70e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   1 MMTNLFSTFdPSTSLLNLPINWSSTFIGLLLI--PTMYWLMP-LWILLMWNkrnlnFHNEFKTLIGPKSFNGT--TFMFI 75
Cdd:MTH00073   1 MNLSFFDQF-LSPTLLGIPLIMLAMLLPWLLFptPTNKWLNNrLSTLQIWF-----LQNFTKQLMLPLNTPGHkwALILT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  76 SMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWP 155
Cdd:MTH00073  75 SLMVFLITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRP 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 304322857 156 GTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMT--ILISSQMLLLT-LESAVSLIQAYVFSILSTLYSSE 223
Cdd:MTH00073 155 LALGVRLTANLTAGHLLIQLISTATLVLLPLMPTvsILTMIVLFLLTlLEIAVAMIQAYVFVLLLSLYLQE 225
ATP-synt_A pfam00119
ATP synthase A chain;
54-222 1.95e-16

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 74.83  E-value: 1.95e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857   54 FHNEFKTLIGPKSFNGTTFMFISMLIMMMFNNFMGLL---PYIFTKSSDMTLTFSIAMPMWLSFMQFG-WINNTKHMLAH 129
Cdd:pfam00119  41 VDNIVKDNIGKKKGRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGiKKHGLGGYFKK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  130 LVLQGTPTALMSFMVLIETISNTIWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISS---QMLLLTLESAVS 206
Cdd:pfam00119 121 LFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLIFALLSAGFLLGVIPpllGVAWTLFELLVA 200

                         170
                  ....*....|....*.
gi 304322857  207 LIQAYVFSILSTLYSS 222
Cdd:pfam00119 201 FIQAYVFTMLTAVYIS 216
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 69-220 5.89e-14

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 67.79  E-value: 5.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  69 GTTFMFIsmlimmMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFG-WINNTKHMLAHLVLQGTPtALMSFMVLIE 147
Cdd:COG0356   62 LTLFLFI------LVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGiKKKGLGGYLKHLFFPPFP-WLAPLMLPIE 134

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 304322857 148 TISNTIWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISsqMLLLTLESAVSLIQAYVFSILSTLY 220
Cdd:COG0356  135 IISELARPLSLSLRLFGNMFAGHIILLLLAGLAPFLLLGVLSLLLP--VAWTAFELLVGFLQAYIFTMLTAVY 205
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 72-225 1.32e-13

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 67.72  E-value: 1.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  72 FMFISMLimmmfnNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISN 151
Cdd:MTH00175  90 FLFIAIL------NILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLIETLSY 163

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 304322857 152 TIWPGTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISSQMLLLT----LESAVSLIQAYVFSILSTLYSSETY 225
Cdd:MTH00175 164 LIRAISLGVRLAANISAGHLLFAILSGFAFNMLSNGLIILSLFPMLIMIfitlLEMAVAVIQAYVFCLLTTIYLGDTI 241
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 54-224 3.88e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 63.52  E-value: 3.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  54 FHNEFKTLIGPKSFNGTTFMfISMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQ 133
Cdd:MTH00172  56 FHGVVKDNLGNEGLKYFPFI-ISLFFFIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPS 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 134 GTPTALMSFMVLIETISNTIWPGTLAIRLVANMIAGYLLLTLL-----GNTGNMISFGLMTILISSQMLLltLESAVSLI 208
Cdd:MTH00172 135 GAPLGLAPLLVLIETVSYISRAISLGVRLAANLSAGHLLFAILagfgfNMLCASGFLSLFPLLIMVFITL--LEIAVAVI 212

                        170
                 ....*....|....*.
gi 304322857 209 QAYVFSILSTLYSSET 224
Cdd:MTH00172 213 QAYVFCLLTTIYLADT 228
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 70-220 2.02e-10

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 59.37  E-value: 2.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  70 TTFMFIsmlimmMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLsFMQFGWI--NNTKHMLAHLVlQGTPTALMSFMVLIE 147
Cdd:PRK13419 176 TVFFFI------LVCNLLGLVPYGATATGNINVTLTLAVFTFF-ITQYAAIkaHGIKGYLAHLT-GGTHWSLWIIMIPIE 247

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 304322857 148 TISNTIWPGTLAIRLVANMIAGYLLLTLLGNtgnmISFGLMTILISSQM------LLLTLESAVSLIQAYVFSILSTLY 220
Cdd:PRK13419 248 FIGLFTKPFALTVRLFANMTAGHIVILSLIF----ISFILKSYIVAVAVsvpfaiFIYLLELFVAFLQAYIFTMLSALF 322
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 38-224 2.29e-09

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 55.72  E-value: 2.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  38 LMPLWILLMWNKRNLNFHNEFKTLIGPKSFNGTTFMfISMLIMMMFNNFMGLLPYIFTKSSDMTLTFSIAMPMWLSFMQF 117
Cdd:MTH00174  59 LVPNRILVGLELIYSHFYTVLKDNLGNKGGNYLAFV-LSLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLA 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857 118 GWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPGTLAIRLVANMIAGYLLLTLLGNTG-NMISFGLMT---ILIS 193
Cdd:MTH00174 138 GLITFRFNFFSILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAANISSGHLLFSIIASFAwKMINTGILIgsfVPFA 217

                        170       180       190
                 ....*....|....*....|....*....|.
gi 304322857 194 SQMLLLTLESAVSLIQAYVFSILSTLYSSET 224
Cdd:MTH00174 218 ILIFVTILEMAVAIIQAYVFTLLTIVYLRDT 248
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 69-220 6.17e-09

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 54.42  E-value: 6.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  69 GTTFMFIsmlimmMFNNFMGLLP-YIFTKSSDMTLTFSIAMPMWLSFMQFG-WINNTKHMLAHLVLQgtPTALMSFMVLI 146
Cdd:PRK05815  77 FTLFLFI------LLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGiKKKGLGGYLKEFYLQ--PHPLLLPIEII 148

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 304322857 147 ETISNTIwpgTLAIRLVANMIAGYLLLTLLGNTGNMISFGLMTILISSqMLLLTLESAVSLIQAYVFSILSTLY 220
Cdd:PRK05815 149 SEFSRPI---SLSLRLFGNMLAGELILALIALLGGAGLLLALAPLILP-VAWTIFEIFVGTLQAYIFMMLTIVY 218
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 95-220 1.37e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 45.27  E-value: 1.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 304322857  95 TKSSDMTLTFSIAMPMWLSFMQFGWINNTKHMLAHLVLQGTPTALMSFMVLIETISNTIWPG-TLAIRLVANMIAGYLLL 173
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIVSPMAKTfALTVRLLANMTAGHVII 296

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 304322857 174 TLLGNTGNMI-SFGLMTILISSQMLLLTLESAVSLIQAYVFSILSTLY 220
Cdd:PRK13417 297 LALMGFIFQFqSWGIVPVSVIGSGLIYVLEIFVAFLQAYIFVLLTSLF 344
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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