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Conserved domains on  [gi|357017938|ref|YP_004934960|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Pielomastax zhengi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-337 2.22e-78

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 242.81  E-value: 2.22e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSS-NSVVNEMSIKYFIVQALASSMLLFAILFIQMK 79
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKkNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEweeTFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKtNSVIILIAILSVLMG 159
Cdd:MTH00160  82 LMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAIIG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 160 AIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMW 239
Cdd:MTH00160 158 AIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLF 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 240 MSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESKWILAMKIRNQPKFVIS 319
Cdd:MTH00160 238 LNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317

                        330
                 ....*....|....*...
gi 357017938 320 MVSLVSNSMLMAAPIFMY 337
Cdd:MTH00160 318 LSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-337 2.22e-78

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 242.81  E-value: 2.22e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSS-NSVVNEMSIKYFIVQALASSMLLFAILFIQMK 79
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKkNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEweeTFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKtNSVIILIAILSVLMG 159
Cdd:MTH00160  82 LMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAIIG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 160 AIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMW 239
Cdd:MTH00160 158 AIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLF 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 240 MSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESKWILAMKIRNQPKFVIS 319
Cdd:MTH00160 238 LNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317

                        330
                 ....*....|....*...
gi 357017938 320 MVSLVSNSMLMAAPIFMY 337
Cdd:MTH00160 318 LSFISLFGLILSSLLFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-280 1.40e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 109.33  E-value: 1.40e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   23 ANSWLAVWVGLEVNLVSFIPL--LYSSNSVVNEMSIKYFIVQALASSMLLFAI--------------LFIQMKSFIEWEE 86
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLigYWGKSPRSSEAGMKYFLLTLLGSSILLFGIslmynytgtlsfdeLSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   87 TFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLL-MTWQKIAPM-------VGLSYCMKTNSVIILIAILSVLM 158
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYglirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  159 GAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV----SETIWEIYFIMYSFLSILVVMMF-----DLNKIFFLNQVFGSNN 229
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 357017938  230 ENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITT 280
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-293 7.79e-27

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 110.21  E-value: 7.79e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   7 IMFLSVLlmGTLLTLSANSWLAVWVGLEvnLVSfIPL-----LYSSNSVVNEMSIKYFIVQALASSMLLFAILFI----- 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLE--LLS-LSLyvlvaFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLygatg 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  77 -----QMKSFIEWEETFITTLLVGSSLLM-----KMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGL----SYCM 142
Cdd:COG1007  182 slnlaGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllVEAF 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 143 KTNS-----VIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIG----GVV--STLSVSETIweIYFIMYSFLSI---L 208
Cdd:COG1007  262 PGLAadwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGylllGLAagTPLGVSAAL--FYLLAYLFMNLgafA 339

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 209 VVMM-----FDLNKIFFLNqvfGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLIT 283
Cdd:COG1007  340 VILLlsrkgGEAEEIEDLA---GLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVIS 416

                        330
                 ....*....|
gi 357017938 284 LYFYLRLAFA 293
Cdd:COG1007  417 AYYYLRVVKA 426
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-324 8.36e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 98.48  E-value: 8.36e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   14 LMGTLLTLSANSWLAVWVGLE-VNLVSFIPLLYSSNSVV-NEMSIKYFIVQALASSMLLFAILFI--------------- 76
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLElQSLCFYVLAGLKRKSRFsTEAGLKYFILGAFSSGLLLFGISLIygftgslnfedlllf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   77 QMKSFIEWEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKT---------NSV 147
Cdd:TIGR01770 192 LSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYilfgfseawQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  148 IILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETI--------WEIYFIMYSFLSILVVMMFDLNK-- 217
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikavlfyIFIYALMSLGAFGVLSLLRSYKDew 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  218 IFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFAslVV 297
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKV--MY 429

                         330       340
                  ....*....|....*....|....*..
gi 357017938  298 LYSESKWILAMKIRNQPKFVISMVSLV 324
Cdd:TIGR01770 430 FDKPERRIPSNPQSKAQSLLLSISALF 456
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-337 2.22e-78

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 242.81  E-value: 2.22e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSS-NSVVNEMSIKYFIVQALASSMLLFAILFIQMK 79
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKkNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEweeTFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKtNSVIILIAILSVLMG 159
Cdd:MTH00160  82 LMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAIIG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 160 AIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMW 239
Cdd:MTH00160 158 AIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLF 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 240 MSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESKWILAMKIRNQPKFVIS 319
Cdd:MTH00160 238 LNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317

                        330
                 ....*....|....*...
gi 357017938 320 MVSLVSNSMLMAAPIFMY 337
Cdd:MTH00160 318 LSFISLFGLILSSLLFLL 335
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-294 6.00e-63

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 203.52  E-value: 6.00e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSSN-SVVNEMSIKYFIVQALASSMLLFAILfIQMK 79
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHhPRATEAATKYFLTQAAASALILFSST-TNAW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEWEETFIT----TLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLsyCMKTNS----VIILI 151
Cdd:MTH00112  80 NTGQWDITQLTnptsCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLL--LMTSNSlnptLLLTL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 152 AILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNEN 231
Cdd:MTH00112 158 AILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKS 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357017938 232 KFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFAS 294
Cdd:MTH00112 238 PTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYIS 300
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-294 8.40e-62

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 200.84  E-value: 8.40e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLL-YSSNSVVNEMSIKYFIVQALASSMLLFAILfIQMK 79
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILmKKHNPRSTEAATKYFLTQATASMLLMMAII-INLM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEWEETFIT----TLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGL---SYCMKTNsVIILIA 152
Cdd:MTH00105  80 YSGQWTITKLTnptaSTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILyqiSPSINPN-LLLTLA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 153 ILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENK 232
Cdd:MTH00105 159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 357017938 233 FFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFAS 294
Cdd:MTH00105 239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYST 300
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-339 3.12e-58

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 191.68  E-value: 3.12e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLL-YSSNSVVNEMSIKYFIVQALASSMLLFAILFIQMK 79
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILsSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 S---FIEWEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMK--TNSVIILIAIL 154
Cdd:MTH00041  81 SgswSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNllNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 155 SVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFF 234
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 235 KSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESKWILAMKIRNQP 314
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|....*....
gi 357017938 315 KFV----ISMVSLVSNSMLMAAPIFMYFL 339
Cdd:MTH00041 321 ITVygviLSILSSISILGLLLIPLFLSFL 349
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-339 1.37e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 189.75  E-value: 1.37e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSS-NSVVNEMSIKYFIVQALASSMLLFAILfIQMK 79
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKThHPRATEAATKYFLTQASASALILFSST-INAW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEWE----ETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGL---SYCMKTNsVIILIA 152
Cdd:MTH00070  80 FTGEWTimnmQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLiqiSHLLNSN-LLIIMG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 153 ILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENK 232
Cdd:MTH00070 159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNP 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 233 FFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFA-SLVVLYSESKWILAMKIR 311
Cdd:MTH00070 239 TLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAmSLTTSPNTSNSKLYWRFK 318

                        330       340
                 ....*....|....*....|....*...
gi 357017938 312 NQPKFVISMVSLVSNSMLMAAPIFMYFL 339
Cdd:MTH00070 319 NKTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 6-339 8.20e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 182.01  E-value: 8.20e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   6 KIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSSNSVVN-EMSIKYFIVQALASSMLLFAILFIQMKSFIEW 84
Cdd:MTH00144   6 NLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSEsESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  85 EETFITtllvgSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTN---SVIILIAILSVLMGAI 161
Cdd:MTH00144  86 SMSLLL-----LGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYwlaYLLCVISVLSALVGSI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 162 GGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMWMs 241
Cdd:MTH00144 161 GGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISL- 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 242 LLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYseskwilamKIRNQPKFVISMV 321
Cdd:MTH00144 240 LLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSS---------KSKKSNSSKVLNS 310

                        330
                 ....*....|....*...
gi 357017938 322 SLVSNSMLMAAPIFMYFL 339
Cdd:MTH00144 311 SIISLNLLGGLLFLLLYL 328
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-293 1.68e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 179.23  E-value: 1.68e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLL---YSSNSVvnEMSIKYFIVQALASSMLLFAILfiq 77
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMaqhHHPRAV--EATTKYFLTQATAAAMILFAST--- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  78 MKSFI--EWEETFIT----TLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTNS-VIIL 150
Cdd:MTH00135  76 TNAWLtgQWDIQQMShplpTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPtLLIT 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 151 IAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNE 230
Cdd:MTH00135 156 LGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTK 235

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357017938 231 NKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFA 293
Cdd:MTH00135 236 APALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYA 298
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-339 2.39e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 178.62  E-value: 2.39e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   1 MNNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSSNSVVN-EMSIKYFIVQALASSMLLFAIL----F 75
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKvEATTKYFIIQATASALLLFGGLlnawT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  76 IQMKSFIEWEETFITTLLVgSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLS--YCMKTNSVIILIAI 153
Cdd:MTH00200  81 SGQWGISEMLGPLSETLIL-LALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 154 LSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKF 233
Cdd:MTH00200 160 LSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 234 FKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESKWILAMKIRNQ 313
Cdd:MTH00200 240 LSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKS 319

                        330       340
                 ....*....|....*....|....*.
gi 357017938 314 PKFVISMVSLVSNSMLMAAPIFMYFL 339
Cdd:MTH00200 320 NSNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-320 4.90e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 164.46  E-value: 4.90e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   8 MFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLL-YSSNSVVNEMSIKYFIVQALASSMLLFAIlfiqMKSFIEWEE 86
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLsQNKSITENEGAMKYFLFQEFGSALLLMGG----SLSFSNLYL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  87 TFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTNSVIILIAILSVLMGAIGGLNQ 166
Cdd:MTH00197  78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 167 TSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMWMSLLSLG 246
Cdd:MTH00197 158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 357017938 247 GLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESKWILAMKIRNQPKFVISM 320
Cdd:MTH00197 238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLM 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-295 2.00e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 157.63  E-value: 2.00e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   5 TKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSSN-SVVNEMSIKYFIVQALASSMLLFAIlfiQMKSFIE 83
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKmNQESEAAVKYFLAQALGSGLLLLGM---TMMWSFP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  84 WEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTN--SVIILIAILSVLMGAI 161
Cdd:MTH00011  84 SLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNilPMMTSMAAMSALAGGL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 162 GGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMWMS 241
Cdd:MTH00011 164 GGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIM 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 357017938 242 LLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASL 295
Cdd:MTH00011 244 LLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM 297
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-280 1.40e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 109.33  E-value: 1.40e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   23 ANSWLAVWVGLEVNLVSFIPL--LYSSNSVVNEMSIKYFIVQALASSMLLFAI--------------LFIQMKSFIEWEE 86
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLigYWGKSPRSSEAGMKYFLLTLLGSSILLFGIslmynytgtlsfdeLSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   87 TFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLL-MTWQKIAPM-------VGLSYCMKTNSVIILIAILSVLM 158
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYglirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  159 GAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV----SETIWEIYFIMYSFLSILVVMMF-----DLNKIFFLNQVFGSNN 229
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 357017938  230 ENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITT 280
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-293 7.79e-27

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 110.21  E-value: 7.79e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   7 IMFLSVLlmGTLLTLSANSWLAVWVGLEvnLVSfIPL-----LYSSNSVVNEMSIKYFIVQALASSMLLFAILFI----- 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLE--LLS-LSLyvlvaFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLygatg 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  77 -----QMKSFIEWEETFITTLLVGSSLLM-----KMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGL----SYCM 142
Cdd:COG1007  182 slnlaGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllVEAF 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 143 KTNS-----VIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIG----GVV--STLSVSETIweIYFIMYSFLSI---L 208
Cdd:COG1007  262 PGLAadwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGylllGLAagTPLGVSAAL--FYLLAYLFMNLgafA 339

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 209 VVMM-----FDLNKIFFLNqvfGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLIT 283
Cdd:COG1007  340 VILLlsrkgGEAEEIEDLA---GLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVIS 416

                        330
                 ....*....|
gi 357017938 284 LYFYLRLAFA 293
Cdd:COG1007  417 AYYYLRVVKA 426
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-290 3.79e-25

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 105.29  E-value: 3.79e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   8 MFLSVLLM--GTLLTLSANSWLAVWVGLEV-NLVSFIPLLYSSNSVV-NEMSIKYFIVQALASSMLLFAILFI------- 76
Cdd:PRK05777 105 FYLLVLFAllGMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRsLEAAIKYFVLGALASGFLLYGMSLLygatgsl 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  77 ---QMKSFIEWEETFITTLLVG-----SSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGL---------S 139
Cdd:PRK05777 185 sfaGIAKALADGSGNSLLLLFGlvfllVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgG 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 140 YCMKTNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIG----GVV--STLSVSETIweIYFIMYSFLSI----LV 209
Cdd:PRK05777 265 LSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGyllvGLAagTAEGYSAVL--FYLLAYLFMTLgafgVI 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 210 VMM----FDLNKIFFLNqvfGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLY 285
Cdd:PRK05777 343 SLLrrkgGEAESISDFA---GLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAF 419


                 ....*
gi 357017938 286 FYLRL 290
Cdd:PRK05777 420 YYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 12-290 1.61e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 100.48  E-value: 1.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  12 VLLMGTLLTLSANSWLAVWVGLEV-NLVSFIPLLYSSNSVVN-EMSIKYFIVQALASSMLLF------------AILFIQ 77
Cdd:MTH00199 105 IVALGSLLLVSSINWLSIYLAIELqTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFgcallygltgetSIQGIN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  78 MKSFIEWEETFITTllvgsSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTNSVIILIAILSVL 157
Cdd:MTH00199 185 SILTGDVGKILITI-----SLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSII 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 158 MGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV----SETIWEIYFIMYSFLSI---LVVMMFDLNKIFFLnQVFGSNNE 230
Cdd:MTH00199 260 YGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSIcsfSIILSLKLTKGLIV-EVSGLSRK 338

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 231 NKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRL 290
Cdd:MTH00199 339 NPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-324 8.36e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 98.48  E-value: 8.36e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   14 LMGTLLTLSANSWLAVWVGLE-VNLVSFIPLLYSSNSVV-NEMSIKYFIVQALASSMLLFAILFI--------------- 76
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLElQSLCFYVLAGLKRKSRFsTEAGLKYFILGAFSSGLLLFGISLIygftgslnfedlllf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   77 QMKSFIEWEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKT---------NSV 147
Cdd:TIGR01770 192 LSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYilfgfseawQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  148 IILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETI--------WEIYFIMYSFLSILVVMMFDLNK-- 217
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikavlfyIFIYALMSLGAFGVLSLLRSYKDew 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  218 IFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFAslVV 297
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKV--MY 429

                         330       340
                  ....*....|....*....|....*..
gi 357017938  298 LYSESKWILAMKIRNQPKFVISMVSLV 324
Cdd:TIGR01770 430 FDKPERRIPSNPQSKAQSLLLSISALF 456
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-290 4.00e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 95.48  E-value: 4.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  13 LLMGTLLTLSANSWLAVWVGLEVNLVS-FIPLLYSSNSVVN-EMSIKYFIVQALASSMLLFA-----------------I 73
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSlFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFGcallcgttgglhlsyinL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  74 LFIQMKSFIEWEeTFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTNSVIILIAI 153
Cdd:MTH00196  82 VLNSGQSFSSVS-VPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 154 LSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV----SETIWEIYFIMYSFLSILVVMMFDL--NKIFFLNQVFGS 227
Cdd:MTH00196 161 FSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSICVFSIILAlnVYKNLIIEFSGL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357017938 228 NNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRL 290
Cdd:MTH00196 241 SRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 8-290 9.73e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.58  E-value: 9.73e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   8 MFLSVLLMGTLLTLSANSWLAVWVGLEVNLV-SFIPLLYSSNSVVNEMSIKYFIVQALASSMLLFAILFIQ-------MK 79
Cdd:COG0651  111 PLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLaSYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYgatgtlnMA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 SFIEWEETFITTLLVGSSLL------MKMGAAPMHFWLPEVMKYMSWSNCLLL---MTwqKIA---------PMVGLSYC 141
Cdd:COG0651  191 DLAARLAELDPGLLLAAFALllvgfgIKAALFPLHFWLPDAYPAAPSPVSALLsglLT--KVGvyailrvltLLFGADPA 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 142 MKTNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIG------GVVSTLSVSETIweIYFIMYSFLSILVVMMFDL 215
Cdd:COG0651  269 LFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGyillglGLGTPLGLAGAL--FHLLNHALAKALLFLAAGA 346

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 216 nkiffLNQVFGSNNENKF---FKSMMWMSL------LSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYF 286
Cdd:COG0651  347 -----IERATGTRDLDKLgglGKRMPLTAAafligaLALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAY 421


                 ....
gi 357017938 287 YLRL 290
Cdd:COG0651  422 FVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 8-290 3.62e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 73.35  E-value: 3.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   8 MFLSVLLMGTLLTLSANsWLAVWVGLEVN-LVSFI---------PLLYSSNSVVNEMSIKYFIVQALASSMLLFA----- 72
Cdd:MTH00198 193 LVLIVGLGGLLLIESAN-WLTIYLALEFQtLALFIlagegsqpgSHFPSPGNTPPESGLKYWILGAMSSGFYLFGcalyf 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  73 -----------ILFIQMKSF-IEWEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSY 140
Cdd:MTH00198 272 gftgnegmlgtILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTS 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 141 CMKTNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIG--------GVVSTLSVSETIWEIYFI--MYSFLSILVV 210
Cdd:MTH00198 352 LVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGfiligvsaGTYESLQASWTYAVTYLVsaLASFTVICTL 431

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 211 MMF---------------DLNKIFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIV----IQTLMEEKMVI 271
Cdd:MTH00198 432 EEFgtrtptsrqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIlvgsIKIAFSSSLSI 511

                        330       340
                 ....*....|....*....|..
gi 357017938 272 --LIGLL-VITTLITLYFYLRL 290
Cdd:MTH00198 512 yyLVALFaIICTCISAFYYIRI 533
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 57-290 2.36e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 61.43  E-value: 2.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  57 KYFIVQALASSMLLFAILFIQMK-----------SFIEWEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLL 125
Cdd:PRK08375 160 KYLIVGLIGSTFLLIGVGLLYGVtgtlnmadlagALAENPTVVTAFGFVLLALALKAAVFPLHTWLPRAYPAAPPVVTAL 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 126 L----------MTWQKIAPMVGLSYCMKTN--SVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVstlsvset 193
Cdd:PRK08375 240 LsglvtkvavyALIRIYFTVFGGDFRFALGlgWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYIL-------- 311

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 194 iweiyfIMYSFLSILVVM---------MFDLNKIFF----LNQVFGSNNENKF---FKSMMWMSL------LSLGGLPPF 251
Cdd:PRK08375 312 ------LGLALLTPLALAagllhllhhALMKGALFLaagaIEVTYGTRRLSELsglGRRMPLTAAafavasLSLIGVPPT 385

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 357017938 252 LGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRL 290
Cdd:PRK08375 386 SGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRI 424
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 146-324 5.01e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 60.37  E-value: 5.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 146 SVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFL-SILVVMMFDLNKIFF---- 220
Cdd:PRK12667 296 PILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINhAIAKSLLFLASGVFIhaag 375

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 221 ---LNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFaslVV 297
Cdd:PRK12667 376 trdIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWY---SL 452

                        170       180
                 ....*....|....*....|....*..
gi 357017938 298 LYSESKWILAMKIRNQPKFVISMVSLV 324
Cdd:PRK12667 453 FFGKPKSGEEVEHKESPSMSVVILVLA 479
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
144-292 2.47e-09

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 58.42  E-value: 2.47e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 144 TNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLS------VSETIWEIYFIMY--SFLSILVVMMFDL 215
Cdd:PRK12663 271 LHPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLAlgtpagINGAIFYLVHDMVvkTALFLIAGSLVRL 350

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 357017938 216 NKIFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAF 292
Cdd:PRK12663 351 TGYRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFF 427
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
147-289 1.03e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.13  E-value: 1.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 147 VIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV------SETIweIYFIMYSFLSI---LVVMMFDL-- 215
Cdd:PRK02504 278 LFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAgteagyASMV--FYLLAYLFMNLgafACVILFSLrt 355

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 216 --NKIfflNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPK----WIVIQTlmEEKMVILIGLlvITTLITLYFYLR 289
Cdd:PRK02504 356 gtDQI---SDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKiylfWAGWQA--GLYLLVLVGL--VTSVISIYYYIR 428
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 53-292 1.07e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 53.18  E-value: 1.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  53 EMSIKYFIVQALASSMLLFAI--------------LFIQMKSFIEWEETFITTLLVGSsLLMKMGAAPMHFWLPEVM-KY 117
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGIallygqygtlnmayLAVKMSENPTVVAKIALALFIAG-LAMKSGAVPVHMWLPDAYpAA 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 118 MSWSNCLLLMTwqKIAPMVGLS------YCMKTNS-----VIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVS 186
Cdd:PRK08376 251 PSSISAMLLVI--KQAGLYALArvlfsiYGPAINLatvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLL 328

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 187 TLSVSET------------------IWEI--YFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKSMMWMSLLSLG 246
Cdd:PRK08376 329 GLGVGLAalgdpamasygeialaggIYHIvnHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIV 408

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 357017938 247 GLPPFLGFFPKWIVIQTLMEEKmVILIGLLVITTLITLYFYLRLAF 292
Cdd:PRK08376 409 GLPPFNGFASKWLIYESSALFN-PILGVIAMIGSVLTLASFVKVFH 453
ndhB CHL00049
NADH dehydrogenase subunit 2
 9-290 2.22e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 49.23  E-value: 2.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   9 FLSVLLMGTL---LTLSANSWLAVWVGLE-VNLVSFIPLLYSSNSV-VNEMSIKYFIVQALASSMLLF------------ 71
Cdd:CHL00049 113 FLLFVLTATLggmFLCGANDLITIFVALEcLSLCSYLLSGYTKKDVrSNEATMKYLLMGGASSSILVYgfswlyglsgge 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  72 --------AILFIQM-KSFIEWeetfITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCM 142
Cdd:CHL00049 193 ielqeivnGLINTQMyNSPGIS----IALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIF 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 143 KT---------NSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSEtIWEIYFIMYSFLSILVVM-- 211
Cdd:CHL00049 269 DIpfyfssnewHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGD-SNDGYASMITYMLFYIFMnl 347

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 212 -MFDLNKIFFLNQvfGSNN---------ENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTL 281
Cdd:CHL00049 348 gTFACIVLFGLRT--GTDNirdyaglytKDPFLALSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSV 425


                 ....*....
gi 357017938 282 ITLYFYLRL 290
Cdd:CHL00049 426 ISIYYYLKI 434
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 144-290 5.27e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 48.02  E-value: 5.27e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 144 TNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV---SETIWEIYFIMY-----SFLSILVVMMFDL 215
Cdd:PRK07691 274 THYLILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVGVAMmteSGMIGAIYYLIHdmivkAALFLLIGIMIKI 353

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 357017938 216 NKIFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRL 290
Cdd:PRK07691 354 TGTTDLKKMGGLIKRYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIKI 428
PRK12650 PRK12650
DUF4040 family protein;
83-296 1.37e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 46.96  E-value: 1.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  83 EWEE----TFITTLLVGSSLLMKMGAAPMHFWLPEVM------------KYMSWSNCLLLMTWQKIapmvgLSYCMKTNS 146
Cdd:PRK12650 199 VWAEkpglTTVVAVLIAVAAFTKSAQFPFHFWLPEAMaaitpvsaflhaAAVVKAGIYLLLRFSPV-----FHDVAVWNW 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 147 VIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVS----------ETIWEIYFIMYSFLSILVV----MM 212
Cdd:PRK12650 274 LLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGtpfaltaavvHTLAHALFKSSLFMLIGVVdhqaGT 353

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 213 FDLNKIFFLnqvfgsNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEK-----MVILIGLLVITTLITLYFY 287
Cdd:PRK12650 354 RDIRRLGSL------WRRMPFTFVSVTIAALSMAAVPPLFGFVSKEGMLTAFLEAPggnagVVLLLVGAALGAVFTFAYS 427


                 ....*....
gi 357017938 288 LRLAFASLV 296
Cdd:PRK12650 428 ARLVLGAFV 436
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 9-288 5.37e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 44.81  E-value: 5.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   9 FLSVLLMGTLLTLSANsWLAVWVGLEVNLVSFIPLL-YSSNSVVNEMSIKYFIVQALASSMLLFAILFIQMKSF------ 81
Cdd:PRK06589 122 FNLTILIGVLIALSSD-LFTMFVCYELLTISTAFLIgHTRNNISLSGGYKYLKILMISALLLFLPAVILIYTKTgnldfv 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  82 ---IEWEETFITTLLVGSSLLMKMGAAPMHFWLPEVMKYMSWSNCLL---------LMTWQKIAPMV-GLSYC---MKTN 145
Cdd:PRK06589 201 sggLFSKNQSIILLLMFIYGIAKTAIFPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfGLSYLqriFAEF 280

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 146 SVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSV----SETIWEIYFIMYSFLSI----LVVMMFDLNK 217
Cdd:PRK06589 281 NWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFIltpkALGAAILHLVSHSFAKIclfySMGSIYSLKK 360

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 357017938 218 IFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMV---ILIGLLVITTLITLYFYL 288
Cdd:PRK06589 361 EDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPwlsIIVMLVVIASSILSALYL 434
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 145-285 2.50e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 42.65  E-value: 2.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 145 NSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSILVvmmfdLNKIFF---- 220
Cdd:PRK12665 273 DTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIYYVAHHITV-----QTTLFLvvgl 347

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 357017938 221 ---------LNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMV---ILIGLLVITTLITLY 285
Cdd:PRK12665 348 ierqagsssLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWlawALVAGGVVTSLLTLY 424
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-289 3.34e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 42.29  E-value: 3.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   2 NNATKIMFLSVLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSSNSVVNEMSIKYFIVQALASSMLLFAILFIQMK-- 79
Cdd:PRK08668  96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIYAKtg 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  80 --SFIEWEETF----------ITTLLVGSSLLMKMGAAPMHFWLPEVMK-------------------YMSWSNCLLLMT 128
Cdd:PRK08668 176 tfDFADISQGLindtstgfalIVFLFLLAFGVAKAGIFPLHVWAPDAYSeapqsfsavlsgqlsklgaYGFLLVLYVLPG 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 129 WQKIAPMVGLSYCMKTNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIMYSFLSIL 208
Cdd:PRK08668 256 TKLFSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHAL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 209 VVMMFDL--------NKIFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITT 280
Cdd:PRK08668 336 FKGLFFLifaaviyrTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGS 415


                 ....*....
gi 357017938 281 LITLYFYLR 289
Cdd:PRK08668 416 IGSFLYVFR 424
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 147-185 6.90e-04

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 41.22  E-value: 6.90e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 357017938 147 VIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVV 185
Cdd:COG1008  277 LLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVL 315
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 12-303 7.14e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 40.62  E-value: 7.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  12 VLLMGTLLTLSANSWLAVWVGLEVNLVSFIPLLYSSNSVVNemsiKYFIVQALASSMLLFAILFIQMksfieweetfitt 91
Cdd:MTH00091   2 FLSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFN----YFVLQESLGLLFLLFSFGYFQF------------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  92 llvgSSLLMKMGAAPMHFWLPEVMKYMSWSNCLLLMTWQKIAPMVGLSYCMKTNSVIILIAILSVLMGAIggLNQTSLRK 171
Cdd:MTH00091  65 ----LILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQM--FLLKSYKN 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 172 MMAYSSIshiggvvstlsvSETIWEIYFIMYSFLSILVVMMFDLNKIFFLNQVFGSNNENKFFKsmmWMSLLSLGGLPPF 251
Cdd:MTH00091 139 LLILSST------------ESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVS---WETLLVFMNLPFS 203

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 357017938 252 LGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYLRLAFASLVVLYSESK 303
Cdd:MTH00091 204 VTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFK 255
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 9-296 1.07e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 40.68  E-value: 1.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938   9 FLSVLLMGTLLTLSANSWLAVWVGLEVNLVS--FIPLLYSSNSVVnEMSIKYFIV------QALASSMLLFAILFIQMKS 80
Cdd:PRK06458 113 MYQLFLFTMLLALTSNNLGLMWVAIEATTLSsaLLVGIYRTRASL-EAAWKYIIIcsvgvaFALFGTILVYANAATVMGD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938  81 ---FIEWEETFITTLLVGSSLL------------MKMGAAPMHFWLPE--------VMKYMS--WSNCLLLMTWQKIAPM 135
Cdd:PRK06458 192 gemAILWTELLKHASLLDPTLMklafvflligfgTKVGLFPMHAWLPDahseapspVSALLSgvLLNVALYAVLRYYILI 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 136 VGLSYCMKTNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIweiyfimYSFLSILVVMMFDL 215
Cdd:PRK06458 272 DAAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPL-------GIFAALLHMLNHSL 344

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 216 NK--IFF-------------LNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVItt 280
Cdd:PRK06458 345 TKsaIFFasgnvlqkygtrdINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLARGPLLIAILLLL-- 422

                        330
                 ....*....|....*.
gi 357017938 281 litlyfYLRLAFASLV 296
Cdd:PRK06458 423 ------LLTLAFAALV 432
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 144-292 1.11e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 40.52  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 144 TNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIGGVVSTLSVSETIWEIYFIM-YS------FLSILVVMMF--- 213
Cdd:COG1009  274 WLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGAYVAALFHLLtHAffkallFLGAGSVIHAtgt 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 214 -DLNKIFFLnqvfgsnnenkfFKSM------MWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMV--ILIGLLVITTLITL 284
Cdd:COG1009  354 rDIRKMGGL------------RKKMpitaitFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLgpLLLAVALLGAFLTA 421


                 ....*...
gi 357017938 285 YFYLRLAF 292
Cdd:COG1009  422 FYSFRLFF 429
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
137-289 2.09e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 39.63  E-value: 2.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 137 GLSYCMKTNSVIILIAILSVLMGAIGGLNQTSLRKMMAYSSISHIG------GVVSTLSVSETIWEI--YFIMYSFLSIL 208
Cdd:PRK06277 258 GLSYFPSAQGVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGyvaaglALGTPLGIVAGIFHAinHVIYKSALFLG 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357017938 209 VVMMFDLNKIFFLNQVFGSNNENKFFKSMMWMSLLSLGGLPPFLGFFPKWIVIQTLMEEKMVILIGLLVITTLITLYFYL 288
Cdd:PRK06277 338 AGIVSYRTKTSNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMM 417


                 .
gi 357017938 289 R 289
Cdd:PRK06277 418 K 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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