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Conserved domains on  [gi|589144540|ref|YP_009003907|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Humphaplotropis culaishanensis (nomen nudum)]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 1.87e-95

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 286.72  E-value: 1.87e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  81 EYPLNWEqqiIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFTkTIIIVSIAI 160
Cdd:MTH00160  81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFII-IIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 161 GALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTFSENSWSINNNVKSPKFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*...
gi 589144540 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160 317 FLSFISLFGLILSSLLFL 334
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 1.87e-95

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 286.72  E-value: 1.87e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  81 EYPLNWEqqiIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFTkTIIIVSIAI 160
Cdd:MTH00160  81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFII-IIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 161 GALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTFSENSWSINNNVKSPKFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*...
gi 589144540 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160 317 FLSFISLFGLILSSLLFL 334
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 3.40e-28

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 110.87  E-value: 3.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   24 SNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII--------------QLEYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   89 QIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLIL-MTWQKIAPMMVL-------SYCIQNSMFTKTIIIVSIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  161 GALGGLNQTSLRQLMAYSSISHLGWMIASI----KISETMWEVYFTVYSLLSLIMVLLFN-----QSKLFFMNQIYTAEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 589144540  232 MNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 4.35e-25

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 105.20  E-value: 4.35e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  77 IIQLEYPLNWEQQIIPSMMISSSLML-----KIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVL---------SY 142
Cdd:COG1007  185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 143 CIQNSMFTKTIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASI------KISETMweVYFTVYSLLSL---IMVL 213
Cdd:COG1007  265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtplGVSAAL--FYLLAYLFMNLgafAVIL 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 214 LFNQSKlffmnqiytAENMNIE-----------IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLT 282
Cdd:COG1007  343 LLSRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNS 413

                        330
                 ....*....|
gi 589144540 283 TITLYYYMRI 292
Cdd:COG1007  414 VISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 1.84e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 94.63  E-value: 1.84e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   17 GTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII----------QLEYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   86 WEQQIIPSM-----MISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIA---PMMVLSYCIQ------NSMFTK 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  152 TIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWE----VYFTVYSLLS------LIMVLLFNQSKLF 221
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSlgafgvLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  222 FMNQIYTAENMNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRIsfsALIMTF 301
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVMYF 430

                         330       340       350
                  ....*....|....*....|....*....|.
gi 589144540  302 SE-NSWSINNNVKSPKFILPTLVTISTLGLI 331
Cdd:TIGR01770 431 DKpERRIPSNPQSKAQSLLLSISALFILFLG 461
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 1.87e-95

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 286.72  E-value: 1.87e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  81 EYPLNWEqqiIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFTkTIIIVSIAI 160
Cdd:MTH00160  81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFII-IIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 161 GALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTFSENSWSINNNVKSPKFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*...
gi 589144540 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160 317 FLSFISLFGLILSSLLFL 334
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-340 2.84e-71

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 225.11  E-value: 2.84e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSIlIIQLEYPLNWE 87
Cdd:MTH00105   7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAI-IINLMYSGQWT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  88 QQIIP----SMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLsYCIQNSMFTKTII---IVSIAI 160
Cdd:MTH00105  86 ITKLTnptaSTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIL-YQISPSINPNLLLtlaILSILI 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 161 GALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMM 240
Cdd:MTH00105 165 GGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLI 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFS-ALIMTFSENSWSINNNVKSPK--F 317
Cdd:MTH00105 245 LLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTNNMKMKWQFENTKpmT 324

                        330       340
                 ....*....|....*....|...
gi 589144540 318 ILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00105 325 LLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-340 6.89e-70

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 221.62  E-value: 6.89e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSIlIIQLEYPLN 85
Cdd:MTH00112   5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSS-TTNAWNTGQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  86 WE----QQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLsYCIQNSMFTKTII---IVSI 158
Cdd:MTH00112  84 WDitqlTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLL-LMTSNSLNPTLLLtlaILST 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 159 AIGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKF 238
Cdd:MTH00112 163 LIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNT 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 239 MMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSAlIMTFSENS------WSINNNV 312
Cdd:MTH00112 243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYIS-TITLPPNTtnmmmkWRTKPKK 321

                        330       340
                 ....*....|....*....|....*...
gi 589144540 313 KSPkfiLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00112 322 NTL---TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 8.53e-67

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 213.63  E-value: 8.53e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILI---IQLEYPLNW 86
Cdd:MTH00070   9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  87 EQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLsYCIQNSMFTKTIII---VSIAIGAL 163
Cdd:MTH00070  89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALL-IQISHLLNSNLLIImglLSTLIGGW 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 164 GGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMMFLT 243
Cdd:MTH00070 168 GGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLT 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 244 LLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFsALIMTFSENS------WSINNNvksPKF 317
Cdd:MTH00070 248 LLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSY-AMSLTTSPNTsnsklyWRFKNK---TNN 323

                        330       340
                 ....*....|....*....|...
gi 589144540 318 ILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00070 324 LLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 8-340 3.83e-64

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 206.71  E-value: 3.83e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILI---IQLEYPL 84
Cdd:MTH00041   7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIqawLSGSWSI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  85 NWEQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQ--NSMFTKTIIIVSIAIGA 162
Cdd:MTH00041  87 NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNllNSNILILCGILSVLVGG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 163 LGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMMFL 242
Cdd:MTH00041 167 WGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFIL 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 243 TLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTFSENS-----WSINNNVKSPKF 317
Cdd:MTH00041 247 SILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSislfsWRNSGNITVYGV 326

                        330       340
                 ....*....|....*....|...
gi 589144540 318 ILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00041 327 ILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-339 7.56e-63

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 203.50  E-value: 7.56e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSIL----------II 78
Cdd:MTH00135   8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  79 QLEYPLnweqqiiPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMmVLSYCIQNSMFTKTII--IV 156
Cdd:MTH00135  88 QMSHPL-------PTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLITlgLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 157 SIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEI 236
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 237 KFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFsALIMTFSENswsiNNNVKSPK 316
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSY-AMTLTISPN----TLNGTTPW 314

                        330       340
                 ....*....|....*....|...
gi 589144540 317 FILPTLVTIstlgLISTSTMIST 339
Cdd:MTH00135 315 RLPSTQLTL----PLAISTTATL 333
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-340 6.41e-58

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 190.57  E-value: 6.41e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLF-SILIIQLEYPL 84
Cdd:MTH00200   5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFgGLLNAWTSGQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  85 NWEQQI--IPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLS--YCIQNSMFTKTIIIVSIAI 160
Cdd:MTH00200  85 GISEMLgpLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 161 GALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMM 240
Cdd:MTH00200 165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALiMTFSENSWSINNNVK---SPKF 317
Cdd:MTH00200 245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTL-LTLSPNQINMMSSWRtksNSNL 323

                        330       340
                 ....*....|....*....|...
gi 589144540 318 ILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00200 324 LVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 3-320 6.94e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 187.40  E-value: 6.94e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIqLEY 82
Cdd:MTH00144   2 SSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIM-YNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  83 PLNWEQqiipSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFTKTIIIVSIA--- 159
Cdd:MTH00144  81 SFSWFS----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLsal 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 160 IGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFM 239
Cdd:MTH00144 157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 240 MFLtLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTFSENSWSINNNVKSPKFIL 319
Cdd:MTH00144 237 ISL-LLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISL 315


                 .
gi 589144540 320 P 320
Cdd:MTH00144 316 N 316
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-337 9.99e-56

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 184.49  E-value: 9.99e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQLEYPLnweq 88
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL---- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  89 QIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFTKTIIIVSIAIGALGGLNQ 168
Cdd:MTH00197  78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 169 TSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKFMMFLTLLSLG 248
Cdd:MTH00197 158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 249 GLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTfseNSWSINNNVKSPKFILPTLVTISTL 328
Cdd:MTH00197 238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILS---NWMINFLMKINLLYSGLFILLMMML 314


                 ....*....
gi 589144540 329 GLISTSTMI 337
Cdd:MTH00197 315 PLLMIFTMI 323
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-331 1.06e-52

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 176.51  E-value: 1.06e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00011   2 MSTFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  81 EYPLnweQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYC--IQNSMFTKTIIIVSI 158
Cdd:MTH00011  82 FPSL---LKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 159 AIGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNQIYTAENMNIEIKF 238
Cdd:MTH00011 159 LAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSM 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 239 MMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSAliMTFSENSWSINNNVKSPKFI 318
Cdd:MTH00011 239 SLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNF--MYLSPTFSSLKSAPYEPKTK 316

                        330
                 ....*....|...
gi 589144540 319 LPTLVTISTLGLI 331
Cdd:MTH00011 317 ILISMCTLSLGLI 329
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 3.40e-28

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 110.87  E-value: 3.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   24 SNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII--------------QLEYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   89 QIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLIL-MTWQKIAPMMVL-------SYCIQNSMFTKTIIIVSIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  161 GALGGLNQTSLRQLMAYSSISHLGWMIASI----KISETMWEVYFTVYSLLSLIMVLLFN-----QSKLFFMNQIYTAEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 589144540  232 MNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-319 1.01e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 105.50  E-value: 1.01e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMN-ESSIKYFIVQAMASTMLLF----------SILIIQLEYPL 84
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFgcallcgttgGLHLSYINLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  85 NWEQQI------IPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFTKTIIIVSI 158
Cdd:MTH00196  84 NSGQSFssvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 159 AIGALGGLNQTSLRQLMAYSSISHLGWMIASIKI-------SETMWEVYFTVYSLLSLIMVLLFNQSKLFFMNqiYTAEN 231
Cdd:MTH00196 164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfesiqASLVYLFIYIIMSICVFSIILALNVYKNLIIE--FSGLS 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 232 MNIEIKFMMF-LTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRIsfsALIMTFSENSW--SI 308
Cdd:MTH00196 242 RRLPILAITLaLTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI---VKILFFQANSFllIS 318

                        330
                 ....*....|.
gi 589144540 309 NNNVKSPKFIL 319
Cdd:MTH00196 319 TKILKKENKIN 329
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 4.35e-25

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 105.20  E-value: 4.35e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  77 IIQLEYPLNWEQQIIPSMMISSSLML-----KIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVL---------SY 142
Cdd:COG1007  185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 143 CIQNSMFTKTIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASI------KISETMweVYFTVYSLLSL---IMVL 213
Cdd:COG1007  265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtplGVSAAL--FYLLAYLFMNLgafAVIL 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 214 LFNQSKlffmnqiytAENMNIE-----------IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLT 282
Cdd:COG1007  343 LLSRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNS 413

                        330
                 ....*....|
gi 589144540 283 TITLYYYMRI 292
Cdd:COG1007  414 VISAYYYLRV 423
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-292 8.41e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 101.44  E-value: 8.41e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   8 LLFLSSLMmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLF----------SIL 76
Cdd:PRK05777 107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygatgSLS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  77 IIQLEYPLNWEQQIIPSM-----MISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVL---------SY 142
Cdd:PRK05777 186 FAGIAKALADGSGNSLLLlfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGL 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 143 CIQNSMFTKTIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKIS-----ETMWeVYFTVYSLLSL---IMVLL 214
Cdd:PRK05777 266 SEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGtaegySAVL-FYLLAYLFMTLgafGVISL 344

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 215 FNqSKLFFMNQIYTAENMNIE---IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMR 291
Cdd:PRK05777 345 LR-RKGGEAESISDFAGLSKRsplLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423


                 .
gi 589144540 292 I 292
Cdd:PRK05777 424 V 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 6.24e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 95.85  E-value: 6.24e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMN-ESSIKYFIVQAMASTMLLFSILIIqleYPLNWEQQI---- 90
Cdd:MTH00199 108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCALL---YGLTGETSIqgin 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  91 ------IPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIApmmVLSYCIQNSMFTKTII---IVSIAIG 161
Cdd:MTH00199 185 siltgdVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIG---VFSILVQIGPVTNVVLicaVLSIIYG 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 162 ALGGLNQTSLRQLMAYSSISHLGWMI--------ASIKISetmwEVYFTVYSLLSLIMVLLFNQSKLF--FMNQIYTAEN 231
Cdd:MTH00199 262 AIGALNQTKIKRLLAYSGIGHMGFILfgvaigsfESIQAS----LIYMIIYVIMSICSFSIILSLKLTkgLIVEVSGLSR 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 589144540 232 MNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRI 292
Cdd:MTH00199 338 KNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 1.84e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 94.63  E-value: 1.84e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   17 GTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII----------QLEYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   86 WEQQIIPSM-----MISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIA---PMMVLSYCIQ------NSMFTK 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  152 TIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMWE----VYFTVYSLLS------LIMVLLFNQSKLF 221
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSlgafgvLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  222 FMNQIYTAENMNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRIsfsALIMTF 301
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVMYF 430

                         330       340       350
                  ....*....|....*....|....*....|.
gi 589144540  302 SE-NSWSINNNVKSPKFILPTLVTISTLGLI 331
Cdd:TIGR01770 431 DKpERRIPSNPQSKAQSLLLSISALFILFLG 461
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-292 6.16e-18

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 84.04  E-value: 6.16e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQLEYP-LNWEQ 88
Cdd:COG0651  112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGtLNMAD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  89 ------------QIIPSMMISSSLMLKIGAAPFHFWFPEVMG-ATSWINCLI--LMTwqKIAP--MMVLSYCI---QNSM 148
Cdd:COG0651  192 laarlaeldpglLLAAFALLLVGFGIKAALFPLHFWLPDAYPaAPSPVSALLsgLLT--KVGVyaILRVLTLLfgaDPAL 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 149 FTKTIIIV----SIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKIsetmwevyFTVYSLLSLIMVLL---FNQSKLF 221
Cdd:COG0651  270 FLGTLLLVlgllTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGL--------GTPLGLAGALFHLLnhaLAKALLF 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 222 FM--NQIYTAENMNIE-----------IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYY 288
Cdd:COG0651  342 LAagAIERATGTRDLDklgglgkrmplTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAY 421


                 ....
gi 589144540 289 YMRI 292
Cdd:COG0651  422 FVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-292 1.03e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 84.14  E-value: 1.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPL---------LANNKNMMMNESSIKYFIVQAMASTMLLF------------- 73
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFgcalyfgftgneg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  74 ---SILIIQLEYP-LNWEQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMF 149
Cdd:MTH00198 279 mlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 150 TKTIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIasIKISETMWE---------VYFTVYSLLSLIMVLLFN---- 216
Cdd:MTH00198 359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL--IGVSAGTYEslqaswtyaVTYLVSALASFTVICTLEefgt 436

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 217 --------QSKLFFMNQIYTAENMNI------EIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSA------LMA 276
Cdd:MTH00198 437 rtptsrqrDGSFGNYNLVRRLVDLTIlsrgqpYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSslsiyyLVA 516

                        330
                 ....*....|....*..
gi 589144540 277 MMAVL-TTITLYYYMRI 292
Cdd:MTH00198 517 LFAIIcTCISAFYYIRI 533
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-296 3.07e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 61.27  E-value: 3.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   6 TKLLFLSSLMMGTVLSvssNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILIIQLEY-P 83
Cdd:PRK08376 125 TLILLLELGMLGMAIT---GDLFNFFVFLEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYgT 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  84 LN------------WEQQIIPSMMISSSLMLKIGAAPFHFWFPEVMG-ATSWINCLILMTWQ----KIAPMMVLSYCIQN 146
Cdd:PRK08376 202 LNmaylavkmsenpTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPaAPSSISAMLLVIKQaglyALARVLFSIYGPAI 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 147 SMFTKTIIIV-----SIAIGALGGLNQTSLRQLMAYSSISHLGWMI-------------ASIKISETMWE--VYFTV--- 203
Cdd:PRK08376 282 NLATVGWVIIilgclTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLlglgvglaalgdpAMASYGEIALAggIYHIVnha 361

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 204 --YSLLSLIMVLLFNQSKLFFMNQIY-TAENMNIEIkFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNmsALMAMMAV 280
Cdd:PRK08376 362 lyKALLFLTAGAVIYETGTRNLNELGgLARTMPKTT-IAFLIGAAAIVGLPPFNGFASKWLIYESSALFN--PILGVIAM 438

                        330
                 ....*....|....*..
gi 589144540 281 LTTI-TLYYYMRISFSA 296
Cdd:PRK08376 439 IGSVlTLASFVKVFHTA 455
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-325 3.72e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 57.58  E-value: 3.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  34 LEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSI-LIIQLEYPLNWE--QQIIPSM--------MISSSLML 102
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVgLLYGVTGTLNMAdlAGALAENptvvtafgFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 103 KIGAAPFHFWFPEVM-GATSWINCLILMTWQKIAPMMVlsYCIQNSMF-------------TKTIIIVSIAIGALGGLNQ 168
Cdd:PRK08375 215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYAL--IRIYFTVFggdfrfalglgwlLAVLALLSMLVGSLAALGQ 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 169 TSLRQLMAYSSISHLGWMIASIKISeTMWEVYFTVYSLL-------SLIM-----VLLFNQSKLFFMNQIytAENMniei 236
Cdd:PRK08375 293 DDVKRVLAYSTVSQMGYILLGLALL-TPLALAAGLLHLLhhalmkgALFLaagaiEVTYGTRRLSELSGL--GRRM---- 365

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 237 KFMM---FLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTFSENSWSINNNVk 313
Cdd:PRK08375 366 PLTAaafAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPPGSEAPKQEA- 444

                        330
                 ....*....|..
gi 589144540 314 SPKFILPTLVTI 325
Cdd:PRK08375 445 PLGMLAPSLALA 456
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-295 3.03e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 54.98  E-value: 3.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  55 ESSIKYFIVQAMASTMLLFSILIIQLEY---------PLNWEQQIIPSMMISSSLMLKIGAA---------------PFH 110
Cdd:PRK12667 164 EAAIKYALIGAVGTTLYFLALAFLYATFgtlnmadlsAKIRGLSFPLTGGLAGNPPLALGVAlalalwaftikaaifPNH 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 111 FWFPEV------------------MGATSWINCLILMTWQKIAPMMVLSyciqnsMFTKTIII---VSIAIGALGGLNQT 169
Cdd:PRK12667 244 FWLPDAhpaapspvsamlsglvvnVGAYAIIRFLYTIFGISPSLIDFRA------ALSPILIIlgaVSAIIGALMMVVQK 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 170 SLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLL-SLIMVLLFNQSKLFfmnqIYTAENMNIE-----------IK 237
Cdd:PRK12667 318 DVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINhAIAKSLLFLASGVF----IHAAGTRDIDelaglgrkmpiAS 393

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 589144540 238 FMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFS 295
Cdd:PRK12667 394 FAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK12650 PRK12650
DUF4040 family protein;
94-298 1.18e-07

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 53.51  E-value: 1.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  94 MMISSSLMLKIGAAPFHFWFPEVMGATSWINCLI---LMTWQKIAPMMVLSYCIQNSMFTKTIIIVS----IAIGALGGL 166
Cdd:PRK12650 212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLhaaAVVKAGIYLLLRFSPVFHDVAVWNWLLIIVgmitALMGAVFAV 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 167 NQTSLRQLMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSlimvLLFnQSKLFFMNQIYTAENMNIEIK--------- 237
Cdd:PRK12650 292 QKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAH----ALF-KSSLFMLIGVVDHQAGTRDIRrlgslwrrm 366

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 238 ----FMMFLTLLSLGGLPPFLGFMPKWMVMQSLVEN-----NMSALMAMMAVLTTITLYYYMRISFSALI 298
Cdd:PRK12650 367 pftfVSVTIAALSMAAVPPLFGFVSKEGMLTAFLEApggnaGVVLLLVGAALGAVFTFAYSARLVLGAFV 436
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
152-296 3.57e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 51.49  E-value: 3.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 152 TIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKI---SETMWEVYFTVYS--------LLSLIMVLLFNQSKL 220
Cdd:PRK12663 277 TMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALgtpAGINGAIFYLVHDmvvktalfLIAGSLVRLTGYRSL 356

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 589144540 221 FFMNQIYTAENMNIEIKFMMFLtllSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSA 296
Cdd:PRK12663 357 QYLGGLYRKEPLFGALFLILIF---AIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFLA 429
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
54-292 3.40e-06

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 48.51  E-value: 3.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  54 NESSIKYFIVQAMASTMLLFSIliiQLEYPLNWEQ----QIIPSMMISSSLML-------------KIGAAPFHFWFPEV 116
Cdd:PRK02504 160 NEAALKYLLIGAASSAIFLYGS---SLLYGLSGGStqlsAIALALITSPSLGLalalvfviagiafKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 117 MGATSWINCLILMTWQKIA----PMMVLSYCIQN------SMFTkTIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGW- 185
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSfdeqwkLLFT-ALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFv 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 186 MIASIKISETMWE---VYFTVYSLLSL---IMVLLFN----QSKLFFMNQIYTAENMnieIKFMMFLTLLSLGGLPPFLG 255
Cdd:PRK02504 316 MIGLVAGTEAGYAsmvFYLLAYLFMNLgafACVILFSlrtgTDQISDYAGLYQKDPL---LTLGLSLCLLSLGGIPPLAG 392

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 589144540 256 FMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRI 292
Cdd:PRK02504 393 FFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-305 2.96e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 45.58  E-value: 2.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFS--ILIIQL 80
Cdd:PRK06589 114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPavILIYTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  81 EYPLNWEQQII----PSMMISSSLMLKIGAA---PFHFWFPEVMGATSWINCLI---------LMTWQKIAPMM----VL 140
Cdd:PRK06589 194 TGNLDFVSGGLfsknQSIILLLMFIYGIAKTaifPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfglsYL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 141 SYCIQNSMFTKTIIIVSIAIGALGGLNQTSLRQLMAYSSISHLGWMI--ASIKISETMWEVYFTVYS------LLSLIMV 212
Cdd:PRK06589 274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALlsAFILTPKALGAAILHLVShsfakiCLFYSMG 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 213 LLFNQSKLFFMNQIYTAENMNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENN---MSALMAMMAVLTTITL-YY 288
Cdd:PRK06589 354 SIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNqpwLSIIVMLVVIASSILSaLY 433

                        330
                 ....*....|....*..
gi 589144540 289 YMRISFSALIMTFSENS 305
Cdd:PRK06589 434 LLKILSSIYKPSLSENS 450
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 155-292 3.91e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 45.34  E-value: 3.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 155 IVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKISETMW---EVYF-----TVYSLLSLIMVLLFNQSKLFFMNQI 226
Cdd:PRK12665 281 LLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGlsgAIYYvahhiTVQTTLFLVVGLIERQAGSSSLRRL 360

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 589144540 227 YTAENMNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMS---ALMAMMAVLTTITLYYYMRI 292
Cdd:PRK12665 361 GGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWlawALVAGGVVTSLLTLYAVARV 429
ndhB CHL00049
NADH dehydrogenase subunit 2
 49-292 5.79e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 44.61  E-value: 5.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  49 KNMMMNESSIKYFIVQAMASTMLL--FSILI------IQLEYPLN--WEQQIIPSMMISSSLML-------KIGAAPFHF 111
Cdd:CHL00049 156 KDVRSNEATMKYLLMGGASSSILVygFSWLYglsggeIELQEIVNglINTQMYNSPGISIALIFitvgigfKLSLAPFHQ 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 112 WFPEV-----------MGATSWINCLILMTwqKIAPMMVLSYCIQNSMFTKTIIIVSIAIGALGGLNQTSLRQLMAYSSI 180
Cdd:CHL00049 236 WTPDVyegsptpvvafLSVTSKVAASALAT--RIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSI 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 181 SHLGW-MIASIKISETMWEVYFTVYSLLSLIMVL-LFNQSKLFFM----NQIYTAENMNIEIKFMMF---LTLLSLGGLP 251
Cdd:CHL00049 314 GQIGYvIIGIIVGDSNDGYASMITYMLFYIFMNLgTFACIVLFGLrtgtDNIRDYAGLYTKDPFLALslaLCLLSLGGIP 393

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 589144540 252 PFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRI 292
Cdd:CHL00049 394 PLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 156-292 2.74e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 42.68  E-value: 2.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 156 VSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKIsetMWEVYFT--VYSLLS--LIMVLLFnqskLFFMNQIYTAEN 231
Cdd:PRK08668 281 ISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGL---GTSLGFAggLFHVFNhaLFKGLFF----LIFAAVIYRTGT 353

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 589144540 232 MNIE----------IKFMMFL-TLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRI 292
Cdd:PRK08668 354 TKISemggliekmpFTFAMYLvAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRP 425
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 95-296 4.88e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 41.86  E-value: 4.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  95 MISSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNS----MFTKTIIIVSIAIGALGGLNQTS 170
Cdd:PRK07234 189 LIALGLLVKGGIFVSGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVpgldLIVRIFGVGTALLGVLFALLEKD 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 171 LRQLMAYSSISHLGWMIASIKISetmwevyfTVYSLLSLIMvllfnQSKLFFMNQIYTAENMNIEIKFM------MFLTL 244
Cdd:PRK07234 269 LKRMLAFSTISQLGFILAAPLVG--------GLYALAHGLV-----KSTLFLCAGALPSRNFTELISQMlgigkwIPLTM 335

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 589144540 245 --LSLGGLPPFLGFMPKWMVMQSLVENNMsALMAMMAVLTTITLYYYMRISFSA 296
Cdd:PRK07234 336 asFSIAGFPLLAGFVSKVLTLKNLLPWQA-IALNLAAVGTAASFWKFIFLPFSA 388
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-257 4.96e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 41.01  E-value: 4.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  14 LMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNessikYFIVQAMASTMLLFSILIIQLeyplnweqqiips 93
Cdd:MTH00091   3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQF------------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  94 mmisSSLMLKIGAAPFHFWFPEVMGATSWINCLILMTWQKIAPMMVLSYCIQNSMFtkTIIIVSIAIGALGGLNQTSLRQ 173
Cdd:MTH00091  65 ----LILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFF--FLLLFGLLICFFQMFLLKSYKN 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 174 LMAYSSISHLGWMIASIKISETMWEVYFTVYSLLSLIMVLLFN-QSKLFFMNQIYTAENMNIEIKFMMFLTLLSLGGLPP 252
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNnVNKLNFVSWETLLVFMNLPFSVTFFVKIFSLSEILK 218


                 ....*
gi 589144540 253 FLGFM 257
Cdd:MTH00091 219 VLGFF 223
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 84-301 2.12e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 39.75  E-value: 2.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540  84 LNWEQQIIPSMMISSSLMLKIGAA-------PFHFWFPEVMGATSWINCLI-----------LMTwqKIAPMMVLSyciq 145
Cdd:COG1009  198 LAAAPTILSSPLLTLILLLLLLGAfgksaqfPLHFWLPDAMEGPTPVSALLhaatmvkagvyLLA--RLSPLFALS---- 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 146 nSMFTKTIIIVSIA---IGALGGLNQTSLRQLMAYSSISHLGWMIASIKISEtmwevyftvyslLSLIMVLLFNQSkLF- 221
Cdd:COG1009  272 -PVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGA------------YVAALFHLLTHA-FFk 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 222 ---FM---NQIYTAENMNIE-----IKFM------MFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTT- 283
Cdd:COG1009  338 allFLgagSVIHATGTRDIRkmgglRKKMpitaitFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLLAVALLGa 417

                        250
                 ....*....|....*....
gi 589144540 284 -ITLYYYMRISFsaliMTF 301
Cdd:COG1009  418 fLTAFYSFRLFF----LVF 432
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
153-328 3.46e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 39.24  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 153 IIIVSIAIGALG---GLNQTSLRQLMAYSSISHLGWMIASIKISETMWEV--------YFTVYSLLSLIMVLLFNQSKLF 221
Cdd:PRK06277 269 LIALSVLAMVFGvvmALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVagifhainHVIYKSALFLGAGIVSYRTKTS 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 222 FMNQIYTAENMNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNMSALMAMMAVLTTITLYYYMRISFSALIMTF 301
Cdd:PRK06277 349 NLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYLIYLKPK 428

                        170       180
                 ....*....|....*....|....*...
gi 589144540 302 SENSWSINNNV-KSPKFILPTLVTISTL 328
Cdd:PRK06277 429 PEELEYKNKKVpKYAVFSLAVLTILCII 456
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 155-284 3.86e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 38.91  E-value: 3.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540 155 IVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASIKIsetmwevyFTVYSLL---------SLIMVLLFnqsklFFMNQ 225
Cdd:COG1008  283 VIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFA--------LNPLGLQgavlqmvshGLITAALF-----LLVGV 349

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 589144540 226 IYT-------------AENMNIEIKFMMFLTLLSLgGLPPFLGFMPKWMVMQSLVENNMsaLMAMMAVLTTI 284
Cdd:COG1008  350 LYDrthtrdiadlgglAKRMPVLAALFLLAALASL-GLPGTSGFVGEFLVLLGAFQVNP--WLAILAALGLI 418
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 8-190 5.99e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 38.38  E-value: 5.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540    8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMmneSSIKYFIVQAMASTMLLFSIL----------- 76
Cdd:TIGR01972 112 LLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIY---AAMKFFLYTLAGSLLMLLAILglyflgggtfd 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144540   77 ---IIQLEYPLNWEQQIIPSMMISssLMLKIGAAPFHFWFPEVMGATSWINCLILM-TWQKIAPMMVLSYCIQ-----NS 147
Cdd:TIGR01972 189 lleLLNLPLPFGVQTWLFLAFFIA--FAVKVPLFPLHTWLPDAHVEAPTAGSVILAgVLLKMGTYGFLRFNLPlfpdaSL 266

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 589144540  148 MFTKTII---IVSIAIGALGGLNQTSLRQLMAYSSISHLGWMIASI 190
Cdd:TIGR01972 267 YFAPVLAalgVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGI 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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